LOCUS       DARPZJ010000001       160150 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.001, whole genome shotgun sequence.
ACCESSION   DARPZJ010000001 DARPZJ010000000
VERSION     DARPZJ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 160150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 160150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..160150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.001"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            599..1288
                     /locus_tag="SLE23_000001"
     CDS             599..1288
                     /locus_tag="SLE23_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8466939.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1275..2483
                     /locus_tag="SLE23_000002"
     CDS             1275..2483
                     /locus_tag="SLE23_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8466940.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2777..4048
                     /gene="serS"
                     /locus_tag="SLE23_000003"
     CDS             2777..4048
                     /gene="serS"
                     /locus_tag="SLE23_000003"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEI8466941.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4597..6081)
                     /gene="guaB"
                     /locus_tag="SLE23_000004"
     CDS             complement(4597..6081)
                     /gene="guaB"
                     /locus_tag="SLE23_000004"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEI8466942.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6586..7281)
                     /locus_tag="SLE23_000005"
     CDS             complement(6586..7281)
                     /locus_tag="SLE23_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEI8466943.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7371..8471)
                     /gene="ychF"
                     /locus_tag="SLE23_000006"
     CDS             complement(7371..8471)
                     /gene="ychF"
                     /locus_tag="SLE23_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEI8466944.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8480..8671)
                     /locus_tag="SLE23_000007"
     CDS             complement(8480..8671)
                     /locus_tag="SLE23_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HEI8466945.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8692..9582)
                     /locus_tag="SLE23_000008"
     CDS             complement(8692..9582)
                     /locus_tag="SLE23_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEI8466946.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9569..10336)
                     /locus_tag="SLE23_000009"
     CDS             complement(9569..10336)
                     /locus_tag="SLE23_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8466947.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10348..11061)
                     /gene="rsmG"
                     /locus_tag="SLE23_000010"
     CDS             complement(10348..11061)
                     /gene="rsmG"
                     /locus_tag="SLE23_000010"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEI8466948.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11293..13194)
                     /gene="mnmG"
                     /locus_tag="SLE23_000011"
     CDS             complement(11293..13194)
                     /gene="mnmG"
                     /locus_tag="SLE23_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEI8466949.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13211..14608)
                     /gene="mnmE"
                     /locus_tag="SLE23_000012"
     CDS             complement(13211..14608)
                     /gene="mnmE"
                     /locus_tag="SLE23_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEI8466950.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14907..15290
                     /locus_tag="SLE23_000013"
     CDS             14907..15290
                     /locus_tag="SLE23_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466951.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15458..16216)
                     /locus_tag="SLE23_000014"
     CDS             complement(15458..16216)
                     /locus_tag="SLE23_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HEI8466952.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16234..17052)
                     /locus_tag="SLE23_000015"
     CDS             complement(16234..17052)
                     /locus_tag="SLE23_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEI8466953.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17049..17405)
                     /gene="rnpA"
                     /locus_tag="SLE23_000016"
     CDS             complement(17049..17405)
                     /gene="rnpA"
                     /locus_tag="SLE23_000016"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEI8466954.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17523..17657)
                     /gene="rpmH"
                     /locus_tag="SLE23_000017"
     CDS             complement(17523..17657)
                     /gene="rpmH"
                     /locus_tag="SLE23_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEI8466955.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18180..19514
                     /gene="dnaA"
                     /locus_tag="SLE23_000018"
     CDS             18180..19514
                     /gene="dnaA"
                     /locus_tag="SLE23_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEI8466956.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19712..20842
                     /gene="dnaN"
                     /locus_tag="SLE23_000019"
     CDS             19712..20842
                     /gene="dnaN"
                     /locus_tag="SLE23_000019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEI8466957.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21071..21313
                     /gene="yaaA"
                     /locus_tag="SLE23_000020"
     CDS             21071..21313
                     /gene="yaaA"
                     /locus_tag="SLE23_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEI8466958.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21300..22424
                     /gene="recF"
                     /locus_tag="SLE23_000021"
     CDS             21300..22424
                     /gene="recF"
                     /locus_tag="SLE23_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEI8466959.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22421..24367
                     /gene="gyrB"
                     /locus_tag="SLE23_000022"
     CDS             22421..24367
                     /gene="gyrB"
                     /locus_tag="SLE23_000022"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEI8466960.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24387..26858
                     /gene="gyrA"
                     /locus_tag="SLE23_000023"
     CDS             24387..26858
                     /gene="gyrA"
                     /locus_tag="SLE23_000023"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEI8466961.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27094..27393
                     /locus_tag="SLE23_000024"
     CDS             27094..27393
                     /locus_tag="SLE23_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEI8466962.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27443..27955
                     /gene="ssb"
                     /locus_tag="SLE23_000025"
     CDS             27443..27955
                     /gene="ssb"
                     /locus_tag="SLE23_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8466963.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27981..28217
                     /locus_tag="SLE23_000026"
     CDS             27981..28217
                     /locus_tag="SLE23_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEI8466964.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28360..30333
                     /locus_tag="SLE23_000027"
     CDS             28360..30333
                     /locus_tag="SLE23_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEI8466965.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30339..30791
                     /gene="rplI"
                     /locus_tag="SLE23_000028"
     CDS             30339..30791
                     /gene="rplI"
                     /locus_tag="SLE23_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEI8466966.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31065..32432
                     /gene="dnaB"
                     /locus_tag="SLE23_000029"
     CDS             31065..32432
                     /gene="dnaB"
                     /locus_tag="SLE23_000029"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEI8466967.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33212..34504
                     /locus_tag="SLE23_000030"
     CDS             33212..34504
                     /locus_tag="SLE23_000030"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEI8466968.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35240..36103
                     /locus_tag="SLE23_000031"
     CDS             35240..36103
                     /locus_tag="SLE23_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8466969.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36232..37854)
                     /locus_tag="SLE23_000032"
     CDS             complement(36232..37854)
                     /locus_tag="SLE23_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8466970.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38103..38624
                     /locus_tag="SLE23_000033"
     CDS             38103..38624
                     /locus_tag="SLE23_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEI8466971.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38810..40540)
                     /gene="spxB"
                     /locus_tag="SLE23_000034"
     CDS             complement(38810..40540)
                     /gene="spxB"
                     /locus_tag="SLE23_000034"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEI8466972.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40705..41523
                     /locus_tag="SLE23_000035"
     CDS             40705..41523
                     /locus_tag="SLE23_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HEI8466973.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41626..41823)
                     /locus_tag="SLE23_000036"
     CDS             complement(41626..41823)
                     /locus_tag="SLE23_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466974.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41992..42570
                     /locus_tag="SLE23_000037"
     CDS             41992..42570
                     /locus_tag="SLE23_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEI8466975.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42665..42802
                     /locus_tag="SLE23_000038"
     CDS             42665..42802
                     /locus_tag="SLE23_000038"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466976.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43615..44118)
                     /locus_tag="SLE23_000039"
     CDS             complement(43615..44118)
                     /locus_tag="SLE23_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEI8466977.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44477..45502
                     /locus_tag="SLE23_000040"
     CDS             44477..45502
                     /locus_tag="SLE23_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8466978.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45849..46727
                     /locus_tag="SLE23_000041"
     CDS             45849..46727
                     /locus_tag="SLE23_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HEI8466979.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47203..47319
                     /locus_tag="SLE23_000042"
     CDS             47203..47319
                     /locus_tag="SLE23_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEI8466980.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48247..48585
                     /locus_tag="SLE23_000043"
     CDS             48247..48585
                     /locus_tag="SLE23_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466981.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48679..48909
                     /locus_tag="SLE23_000044"
     CDS             48679..48909
                     /locus_tag="SLE23_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466982.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49309..49680
                     /locus_tag="SLE23_000045"
     CDS             49309..49680
                     /locus_tag="SLE23_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HEI8466983.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49954..50646)
                     /locus_tag="SLE23_000046"
     CDS             complement(49954..50646)
                     /locus_tag="SLE23_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8466984.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50649..51434)
                     /locus_tag="SLE23_000047"
     CDS             complement(50649..51434)
                     /locus_tag="SLE23_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8466985.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51671..53071
                     /gene="lacG"
                     /locus_tag="SLE23_000048"
     CDS             51671..53071
                     /gene="lacG"
                     /locus_tag="SLE23_000048"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEI8466986.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53096..53413
                     /locus_tag="SLE23_000049"
     CDS             53096..53413
                     /locus_tag="SLE23_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEI8466987.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53426..55099
                     /locus_tag="SLE23_000050"
     CDS             53426..55099
                     /locus_tag="SLE23_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HEI8466988.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55113..56744
                     /locus_tag="SLE23_000051"
     CDS             55113..56744
                     /locus_tag="SLE23_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HEI8466989.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57616..58806
                     /locus_tag="SLE23_000052"
     CDS             57616..58806
                     /locus_tag="SLE23_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HEI8466990.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58940..61129
                     /locus_tag="SLE23_000053"
     CDS             58940..61129
                     /locus_tag="SLE23_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8466991.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61126..62919
                     /locus_tag="SLE23_000054"
     CDS             61126..62919
                     /locus_tag="SLE23_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEI8466992.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            63119..63433
                     /locus_tag="SLE23_000055"
     CDS             63119..63433
                     /locus_tag="SLE23_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8466993.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            63454..63831
                     /locus_tag="SLE23_000056"
     CDS             63454..63831
                     /locus_tag="SLE23_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8466994.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            63841..64614
                     /locus_tag="SLE23_000057"
     CDS             63841..64614
                     /locus_tag="SLE23_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466995.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            64636..66039
                     /locus_tag="SLE23_000058"
     CDS             64636..66039
                     /locus_tag="SLE23_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8466996.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            66221..67405
                     /locus_tag="SLE23_000059"
     CDS             66221..67405
                     /locus_tag="SLE23_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8466997.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            67402..67692
                     /locus_tag="SLE23_000060"
     CDS             67402..67692
                     /locus_tag="SLE23_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466998.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            67689..67910
                     /locus_tag="SLE23_000061"
     CDS             67689..67910
                     /locus_tag="SLE23_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8466999.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            67952..68731
                     /locus_tag="SLE23_000062"
     CDS             67952..68731
                     /locus_tag="SLE23_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEI8467000.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            68798..69292
                     /locus_tag="SLE23_000063"
     CDS             68798..69292
                     /locus_tag="SLE23_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEI8467001.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            69348..69986
                     /locus_tag="SLE23_000064"
     CDS             69348..69986
                     /locus_tag="SLE23_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467002.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            70058..70453
                     /locus_tag="SLE23_000065"
     CDS             70058..70453
                     /locus_tag="SLE23_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8467003.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            70437..72890
                     /locus_tag="SLE23_000066"
     CDS             70437..72890
                     /locus_tag="SLE23_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8467004.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            72887..74914
                     /locus_tag="SLE23_000067"
     CDS             72887..74914
                     /locus_tag="SLE23_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467005.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            74911..75933
                     /locus_tag="SLE23_000068"
     CDS             74911..75933
                     /locus_tag="SLE23_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEI8467006.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            75950..76879
                     /locus_tag="SLE23_000069"
     CDS             75950..76879
                     /locus_tag="SLE23_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8467007.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            77124..77240
                     /locus_tag="SLE23_000070"
     CDS             77124..77240
                     /locus_tag="SLE23_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEI8467008.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            77256..79175
                     /gene="tet(M)"
                     /locus_tag="SLE23_000071"
     CDS             77256..79175
                     /gene="tet(M)"
                     /locus_tag="SLE23_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEI8467009.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            79273..79461
                     /locus_tag="SLE23_000072"
     CDS             79273..79461
                     /locus_tag="SLE23_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEI8467010.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(79519..79872)
                     /locus_tag="SLE23_000073"
     CDS             complement(79519..79872)
                     /locus_tag="SLE23_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467011.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            80403..80825
                     /locus_tag="SLE23_000074"
     CDS             80403..80825
                     /locus_tag="SLE23_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8467012.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            80822..81052
                     /locus_tag="SLE23_000075"
     CDS             80822..81052
                     /locus_tag="SLE23_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467013.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            81550..81750
                     /locus_tag="SLE23_000076"
     CDS             81550..81750
                     /locus_tag="SLE23_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEI8467014.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            81777..82970
                     /locus_tag="SLE23_000077"
     CDS             81777..82970
                     /locus_tag="SLE23_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8467015.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(83038..84603)
                     /gene="guaA"
                     /locus_tag="SLE23_000078"
     CDS             complement(83038..84603)
                     /gene="guaA"
                     /locus_tag="SLE23_000078"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEI8467016.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(84662..85585)
                     /locus_tag="SLE23_000079"
     CDS             complement(84662..85585)
                     /locus_tag="SLE23_000079"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEI8467017.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            85781..86386
                     /locus_tag="SLE23_000080"
     CDS             85781..86386
                     /locus_tag="SLE23_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8467018.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            86694..87710
                     /locus_tag="SLE23_000081"
     CDS             86694..87710
                     /locus_tag="SLE23_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEI8467019.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            87851..89152
                     /locus_tag="SLE23_000082"
     CDS             87851..89152
                     /locus_tag="SLE23_000082"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEI8467020.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            89198..89860
                     /gene="deoC"
                     /locus_tag="SLE23_000083"
     CDS             89198..89860
                     /gene="deoC"
                     /locus_tag="SLE23_000083"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEI8467021.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            89881..90279
                     /locus_tag="SLE23_000084"
     CDS             89881..90279
                     /locus_tag="SLE23_000084"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEI8467022.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            90345..91427
                     /locus_tag="SLE23_000085"
     CDS             90345..91427
                     /locus_tag="SLE23_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8467023.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            91639..93201
                     /locus_tag="SLE23_000086"
     CDS             91639..93201
                     /locus_tag="SLE23_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467024.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            93194..94327
                     /locus_tag="SLE23_000087"
     CDS             93194..94327
                     /locus_tag="SLE23_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467025.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            94327..95283
                     /locus_tag="SLE23_000088"
     CDS             94327..95283
                     /locus_tag="SLE23_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467026.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            95382..96548
                     /gene="deoB"
                     /locus_tag="SLE23_000089"
     CDS             95382..96548
                     /gene="deoB"
                     /locus_tag="SLE23_000089"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEI8467027.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            96572..97390
                     /locus_tag="SLE23_000090"
     CDS             96572..97390
                     /locus_tag="SLE23_000090"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8467028.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            97407..98114
                     /gene="deoD"
                     /locus_tag="SLE23_000091"
     CDS             97407..98114
                     /gene="deoD"
                     /locus_tag="SLE23_000091"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8467029.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(98412..99098)
                     /gene="gpmA"
                     /locus_tag="SLE23_000092"
     CDS             complement(98412..99098)
                     /gene="gpmA"
                     /locus_tag="SLE23_000092"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEI8467030.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(99270..99851)
                     /locus_tag="SLE23_000093"
     CDS             complement(99270..99851)
                     /locus_tag="SLE23_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8467031.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(99984..100667)
                     /gene="rpiA"
                     /locus_tag="SLE23_000094"
     CDS             complement(99984..100667)
                     /gene="rpiA"
                     /locus_tag="SLE23_000094"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEI8467032.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            100986..101399
                     /gene="rpsL"
                     /locus_tag="SLE23_000095"
     CDS             100986..101399
                     /gene="rpsL"
                     /locus_tag="SLE23_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEI8467033.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            101483..101953
                     /gene="rpsG"
                     /locus_tag="SLE23_000096"
     CDS             101483..101953
                     /gene="rpsG"
                     /locus_tag="SLE23_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEI8467034.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            102047..104134
                     /gene="fusA"
                     /locus_tag="SLE23_000097"
     CDS             102047..104134
                     /gene="fusA"
                     /locus_tag="SLE23_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEI8467035.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            104306..105493
                     /gene="tuf"
                     /locus_tag="SLE23_000098"
     CDS             104306..105493
                     /gene="tuf"
                     /locus_tag="SLE23_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEI8467036.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            105900..106208
                     /gene="rpsJ"
                     /locus_tag="SLE23_000099"
     CDS             105900..106208
                     /gene="rpsJ"
                     /locus_tag="SLE23_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEI8467037.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            106239..106868
                     /gene="rplC"
                     /locus_tag="SLE23_000100"
     CDS             106239..106868
                     /gene="rplC"
                     /locus_tag="SLE23_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEI8467038.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            106896..107519
                     /gene="rplD"
                     /locus_tag="SLE23_000101"
     CDS             106896..107519
                     /gene="rplD"
                     /locus_tag="SLE23_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEI8467039.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            107519..107809
                     /gene="rplW"
                     /locus_tag="SLE23_000102"
     CDS             107519..107809
                     /gene="rplW"
                     /locus_tag="SLE23_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEI8467040.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            107848..108681
                     /gene="rplB"
                     /locus_tag="SLE23_000103"
     CDS             107848..108681
                     /gene="rplB"
                     /locus_tag="SLE23_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEI8467041.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            108724..109002
                     /gene="rpsS"
                     /locus_tag="SLE23_000104"
     CDS             108724..109002
                     /gene="rpsS"
                     /locus_tag="SLE23_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEI8467042.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            109025..109372
                     /gene="rplV"
                     /locus_tag="SLE23_000105"
     CDS             109025..109372
                     /gene="rplV"
                     /locus_tag="SLE23_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEI8467043.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            109386..110042
                     /gene="rpsC"
                     /locus_tag="SLE23_000106"
     CDS             109386..110042
                     /gene="rpsC"
                     /locus_tag="SLE23_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEI8467044.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            110045..110479
                     /gene="rplP"
                     /locus_tag="SLE23_000107"
     CDS             110045..110479
                     /gene="rplP"
                     /locus_tag="SLE23_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEI8467045.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            110469..110657
                     /gene="rpmC"
                     /locus_tag="SLE23_000108"
     CDS             110469..110657
                     /gene="rpmC"
                     /locus_tag="SLE23_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEI8467046.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            110682..110948
                     /gene="rpsQ"
                     /locus_tag="SLE23_000109"
     CDS             110682..110948
                     /gene="rpsQ"
                     /locus_tag="SLE23_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEI8467047.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            111006..111374
                     /gene="rplN"
                     /locus_tag="SLE23_000110"
     CDS             111006..111374
                     /gene="rplN"
                     /locus_tag="SLE23_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEI8467048.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            111411..111719
                     /gene="rplX"
                     /locus_tag="SLE23_000111"
     CDS             111411..111719
                     /gene="rplX"
                     /locus_tag="SLE23_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEI8467049.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            111747..112286
                     /gene="rplE"
                     /locus_tag="SLE23_000112"
     CDS             111747..112286
                     /gene="rplE"
                     /locus_tag="SLE23_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEI8467050.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            112305..112490
                     /locus_tag="SLE23_000113"
     CDS             112305..112490
                     /locus_tag="SLE23_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEI8467051.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            112526..112924
                     /gene="rpsH"
                     /locus_tag="SLE23_000114"
     CDS             112526..112924
                     /gene="rpsH"
                     /locus_tag="SLE23_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEI8467052.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            112956..113492
                     /gene="rplF"
                     /locus_tag="SLE23_000115"
     CDS             112956..113492
                     /gene="rplF"
                     /locus_tag="SLE23_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEI8467053.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            113653..114009
                     /gene="rplR"
                     /locus_tag="SLE23_000116"
     CDS             113653..114009
                     /gene="rplR"
                     /locus_tag="SLE23_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEI8467054.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            114030..114530
                     /gene="rpsE"
                     /locus_tag="SLE23_000117"
     CDS             114030..114530
                     /gene="rpsE"
                     /locus_tag="SLE23_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEI8467055.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            114545..114724
                     /gene="rpmD"
                     /locus_tag="SLE23_000118"
     CDS             114545..114724
                     /gene="rpmD"
                     /locus_tag="SLE23_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEI8467056.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            114768..115208
                     /gene="rplO"
                     /locus_tag="SLE23_000119"
     CDS             114768..115208
                     /gene="rplO"
                     /locus_tag="SLE23_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEI8467057.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            115208..116503
                     /gene="secY"
                     /locus_tag="SLE23_000120"
     CDS             115208..116503
                     /gene="secY"
                     /locus_tag="SLE23_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEI8467058.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            116565..117212
                     /locus_tag="SLE23_000121"
     CDS             116565..117212
                     /locus_tag="SLE23_000121"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEI8467059.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            117403..117621
                     /gene="infA"
                     /locus_tag="SLE23_000122"
     CDS             117403..117621
                     /gene="infA"
                     /locus_tag="SLE23_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEI8467060.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            117654..117770
                     /gene="rpmJ"
                     /locus_tag="SLE23_000123"
     CDS             117654..117770
                     /gene="rpmJ"
                     /locus_tag="SLE23_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEI8467061.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            117788..118153
                     /gene="rpsM"
                     /locus_tag="SLE23_000124"
     CDS             117788..118153
                     /gene="rpsM"
                     /locus_tag="SLE23_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEI8467062.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            118181..118570
                     /gene="rpsK"
                     /locus_tag="SLE23_000125"
     CDS             118181..118570
                     /gene="rpsK"
                     /locus_tag="SLE23_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEI8467063.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            118650..119588
                     /locus_tag="SLE23_000126"
     CDS             118650..119588
                     /locus_tag="SLE23_000126"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEI8467064.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            119616..119996
                     /gene="rplQ"
                     /locus_tag="SLE23_000127"
     CDS             119616..119996
                     /gene="rplQ"
                     /locus_tag="SLE23_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEI8467065.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            120268..121107
                     /locus_tag="SLE23_000128"
     CDS             120268..121107
                     /locus_tag="SLE23_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8467066.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            121083..121952
                     /locus_tag="SLE23_000129"
     CDS             121083..121952
                     /locus_tag="SLE23_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8467067.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            121942..122739
                     /locus_tag="SLE23_000130"
     CDS             121942..122739
                     /locus_tag="SLE23_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEI8467068.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            122942..123688
                     /gene="truA"
                     /locus_tag="SLE23_000131"
     CDS             122942..123688
                     /gene="truA"
                     /locus_tag="SLE23_000131"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEI8467069.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(124021..126690)
                     /locus_tag="SLE23_000132"
     CDS             complement(124021..126690)
                     /locus_tag="SLE23_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEI8467070.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(126928..127116)
                     /locus_tag="SLE23_000133"
     CDS             complement(126928..127116)
                     /locus_tag="SLE23_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEI8467071.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            127386..127748
                     /locus_tag="SLE23_000134"
     CDS             127386..127748
                     /locus_tag="SLE23_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8467072.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            127800..129482
                     /locus_tag="SLE23_000135"
     CDS             127800..129482
                     /locus_tag="SLE23_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEI8467073.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            129599..131635
                     /gene="recG"
                     /locus_tag="SLE23_000136"
     CDS             129599..131635
                     /gene="recG"
                     /locus_tag="SLE23_000136"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEI8467074.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            131684..132685
                     /gene="plsX"
                     /locus_tag="SLE23_000137"
     CDS             131684..132685
                     /gene="plsX"
                     /locus_tag="SLE23_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEI8467075.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            132807..133049
                     /gene="acpP"
                     /locus_tag="SLE23_000138"
     CDS             132807..133049
                     /gene="acpP"
                     /locus_tag="SLE23_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEI8467076.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            133317..134321
                     /locus_tag="SLE23_000139"
     CDS             133317..134321
                     /locus_tag="SLE23_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467077.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            134322..135266
                     /locus_tag="SLE23_000140"
     CDS             134322..135266
                     /locus_tag="SLE23_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467078.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            135266..136228
                     /locus_tag="SLE23_000141"
     CDS             135266..136228
                     /locus_tag="SLE23_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467079.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            136255..137169
                     /locus_tag="SLE23_000142"
     CDS             136255..137169
                     /locus_tag="SLE23_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467080.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            137195..138976
                     /locus_tag="SLE23_000143"
     CDS             137195..138976
                     /locus_tag="SLE23_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8467081.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            139324..140010
                     /locus_tag="SLE23_000144"
     CDS             139324..140010
                     /locus_tag="SLE23_000144"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEI8467082.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            140030..143611
                     /gene="smc"
                     /locus_tag="SLE23_000145"
     CDS             140030..143611
                     /gene="smc"
                     /locus_tag="SLE23_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEI8467083.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            143620..144429
                     /locus_tag="SLE23_000146"
     CDS             143620..144429
                     /locus_tag="SLE23_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8467084.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            144440..145438
                     /gene="ftsY"
                     /locus_tag="SLE23_000147"
     CDS             144440..145438
                     /gene="ftsY"
                     /locus_tag="SLE23_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEI8467085.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            145625..147892
                     /gene="gshAB"
                     /locus_tag="SLE23_000148"
     CDS             145625..147892
                     /gene="gshAB"
                     /locus_tag="SLE23_000148"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HEI8467086.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(147981..148433)
                     /locus_tag="SLE23_000149"
     CDS             complement(147981..148433)
                     /locus_tag="SLE23_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEI8467087.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKSNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            148583..149533
                     /locus_tag="SLE23_000150"
     CDS             148583..149533
                     /locus_tag="SLE23_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEI8467088.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            149526..150485
                     /locus_tag="SLE23_000151"
     CDS             149526..150485
                     /locus_tag="SLE23_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEI8467089.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            150482..151237
                     /locus_tag="SLE23_000152"
     CDS             150482..151237
                     /locus_tag="SLE23_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8467090.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            151260..152213
                     /locus_tag="SLE23_000153"
     CDS             151260..152213
                     /locus_tag="SLE23_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8467091.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(152857..153153)
                     /locus_tag="SLE23_000154"
     CDS             complement(152857..153153)
                     /locus_tag="SLE23_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HEI8467092.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            153508..153864
                     /locus_tag="SLE23_000155"
     CDS             153508..153864
                     /locus_tag="SLE23_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8467093.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            153874..154773
                     /locus_tag="SLE23_000156"
     CDS             153874..154773
                     /locus_tag="SLE23_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HEI8467094.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            155289..156020
                     /locus_tag="SLE23_000157"
     CDS             155289..156020
                     /locus_tag="SLE23_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEI8467095.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            156165..158192
                     /locus_tag="SLE23_000158"
     CDS             156165..158192
                     /locus_tag="SLE23_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEI8467096.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            158300..159397
                     /locus_tag="SLE23_000159"
     CDS             158300..159397
                     /locus_tag="SLE23_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEI8467097.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            159704..>160150
                     /locus_tag="SLE23_000160"
     CDS             159704..>160150
                     /locus_tag="SLE23_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467098.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        51703 a        28629 c        32953 g        46865 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctcttttttt aaaagttttt tcgatttcgt ttttcgaaat
      121 cttccagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac ttttttgaag
      181 tttttttcga tagaatcaag cttcgcaagt ggttcttttt taacgactca gttatcttat
      241 catgtcattt ccaacatgtc aacaacttat tttttattat ttaataagtt attggtgttc
      301 ttttgaacaa ataataatat atcaacatca catgtgaaag tcaataagaa aatgcttatt
      361 tatcaacatt tctagcttac atgatcattg gttagttctg gtcctttttc gttcgtcttt
      421 ataactccga gagacgtaaa atccttttgt tttcagttta atgttcatgt tcttgtctta
      481 ttcacaccaa ctagatgtct caccttctaa aattttcctt aacaaagtgc tgcttttatc
      541 tatttctgct tttttttgct agaataatag taacaatatg actctggagg atttatttat
      601 gaaaattttg attgctgacg atgataaaga aatcgttgaa ttattaagta tctatgttca
      661 caatgagggg tatgaagcag taaaggctta tgatgggaaa gaagcattat ctaaaatcag
      721 aacaatccct gatattgaat tacttatttt agatatcatg atgcctgaga tggatgggat
      781 gcaagtagtg aaagagctac gaaaagaatc ccaaatacca atcattatgc tgacagcaaa
      841 aactactgat atggataaga tcaaaggact ggtcgctggt gcagatgatt atgtgaccaa
      901 gccatttaat ccgttagaag taatggctag agtaaagtct ttattacggc gtacaaaaat
      961 gcagattgcc ccagatcagc ctgatgtatt agaagtaaat gcattaatca tcaataaaga
     1021 ctctcatgaa gttaaaacaa tcgatgggaa agaaatccag ttaacagctt tggaattcgg
     1081 tatcctctac ttgcttgcta gtcatcctaa tcgagtattt agcgcggatg aaatttttga
     1141 gcgtgtttgg aaacaagaaa gtattgtctc tgctaaaact gtcatggttc acgttagtca
     1201 tttaagagat aagattgaag aagcaactgg tggtgaaaaa gtcattcaaa ccgtttgggg
     1261 agtgggctat aaaattgacg caagatagta aacgagcaac tgaaaaacgc cgtcggatca
     1321 atttgacttc aaaagaaatc agcgaattgt tagcggaagg aatcatcacg attatccttt
     1381 tgcttctatt aaatgtttct attctggttg ttatcagttc ggtgatcaac agttcacctt
     1441 ctttgacgaa tgcgatttgg gattcaaaga atatttttgc agaacgattg aacactgatt
     1501 tgttctggaa cggccggaat tttattattc cctttttctt tctattagat attggtgttt
     1561 tgtattggcg cttgattcga agatatcgcc aaatgcaatt gcggcatatc atcagcgaac
     1621 ttcactacat cgcaaacgga aattatgatc atcgtatccc ttttgaactg agtggtgact
     1681 taagccgagt ggtaacaagt atcaatggat tggtggatag taccgtagca gcgattgaag
     1741 acgaacgtaa aatcgaaaaa tcaaaagatg aattgatcac gaatgtcagt catgatatcc
     1801 gtaccccact cacgtccatc attggatacc taggactgat agaagatggc cagtatcact
     1861 cagaagaaga tcttttaaag tatacgcata ctgcttatat caaagcaaag cagatgaaat
     1921 ctttagtgga cgacttattt gaatacacta aggtacgcca gcctgctgtc ccggtgaatt
     1981 tttctgcctt tgacatgatc cagttgatcg aacagttagc agctgatttt gagttggaag
     2041 cttctaaaaa aaatatccaa atacttgttc aatcaaaagt agactccctt atcatggatg
     2101 gcgataccga aaaacttgta cgtgtcttca ataatctttt gacgaatgcg ttgaaatacg
     2161 gaaaaggagc aacgaagatc gtaatcgaag tagaacgtat cggttcagaa gttgttgcaa
     2221 cagtcaaaaa taacggagca atgatcccac aacaggcaat cgataatcta ttcgaccgtt
     2281 tttatcgtgt agaagaatct cgttcacaag caactggagg aactggactt ggtttagcaa
     2341 tcgctcaaag cattgtggct ttgcacggcg gatacattta tgcaaaatca gataagcaat
     2401 ggacttcttt catcatgcac cttccaatca agaaaaatga aaaattacct attgatacac
     2461 aggaagttat tgacgaaagc tgaaatattc gctattctta ttacaattat tagaataaat
     2521 gaaaaacaca gaacccagta cactttattc tttttcagag agctgatggc aggtgtaaat
     2581 cagcaaagga taatttggaa gttccagttc gtttacgtgc cctttcgaaa taagaaaggt
     2641 cggttcaaca gccgttatgt gttcaacaag tgcagctgac gctgaacttg ggtggtaccg
     2701 cgaatttcag actgattcgt cccaagaata atgggatgga tcagtctttt tttattttca
     2761 aaaaggagga aatcatatgt tagatgtaaa aatgatgcga caaaatattg aagaagtaca
     2821 agaaaaattg atgactcggg gcgtaaaaaa agaaacatta gctgaattca tggaactaga
     2881 tgaaaatcgt cgtaagctac tagtcaaaag tgaagaatta aaaaaatatc gaaatgatgt
     2941 ttctgctgag atcgcccaat tgaagcgtgc aaaagaagat gcttctgcta aaatcgctga
     3001 aatgaaagaa gtcggtggca acatcaaagc attggatact gaaattgctg aagtggatga
     3061 aaaattgaaa caaattgcaa ctactttgcc aaaccttccc catgattctg tgccagttgg
     3121 aacagatgaa gaggacaatg tagaaatccg tcgttggagc gaaccacgta catttgcttt
     3181 tgaaccaaaa ccacactggg aaattgcaga aaatcttgat attttagatt ttgaacgtgg
     3241 cgcaaaagta gccggtagcc gttttgtcta ttacaaagga ttaggtgctc gattagaacg
     3301 tgctgtctac aacttcatgc ttgatcagca tatttacgaa cacggctata ctgaaatgat
     3361 cactccttat atcgtcaaca gtaaagcgat gtttggtacg ggacaatttc caaaattcaa
     3421 agaagatgtt ttccaattgg agaatactga tctaacatta atcccaacag ctgaagtacc
     3481 attaactaac tattataatg atgaaatttt agatggtgca gatttaccta tttatttcac
     3541 tgcactaagc cctgcttttc gttctgaagc cggaagtgct ggtcgggata cacgaggact
     3601 gattcgtctt caccaattca ataaagtaga aatggtcaaa ttttcggatg tagagcattc
     3661 ttacgaagaa ttggaaaaaa tgacagctga tgcagaagat atcttgaaaa aattgcattt
     3721 gccttatcgt gtgatggcct tatcaactgg agacatgggc ttttctgcag ctaaaactta
     3781 tgacttagaa gtatggatac ctgcacaaga tacttatcgt gaaatcagtt cttgttctaa
     3841 ctgtgaagat ttccaagcac gccgcgcaat gatccgttat cgcgataatg atggaaaaat
     3901 ccactatact catactctga atggttcagg acttgcagtt ggccgtacag tagctgccat
     3961 tttggaaaac taccaaaatg aagatggttc tgtcacagtt ccagaagcgc tcgttcctta
     4021 tatggggaat ctgaaagtta ttaaataaag aggctgtgaa aaagccgctt agtttcgagt
     4081 attaagaaaa attttgtgaa aatggctttc cacatttttg cataaattgg acttaatacc
     4141 gagaaactgg cttttgaaca ccatttatcg agaggttgtg aaatcagcga attaacctga
     4201 gtattagaga aaaaaatgga aaaatagtcc ctcatatttt accgtttgtt gaactaatac
     4261 cgagggtcag ctgattgaac accgtttagt ggagaggtcg taagcctacc ccccagctcc
     4321 tagttacaag gacaaattca aaaaacagct cttcatattt tatgaatgtt gtacttgtga
     4381 ttcggaggtg gcaagggaac actgtttatt caaaaagagg ctgggacaga agcgtttaac
     4441 tccaagaaat aagaagaaat tcacgaaaat tgcttttcaa atttttgtga atttcttctt
     4501 atttccgaag gagttgcttc tacttccgcc gtttatacgt gtttagagcg tgagacaaaa
     4561 gtgttcttta cttttgtccc acgctcttta atgtttttaa gattcaactg aatagtttgg
     4621 tgcttctttt gtgatttgta catcatgagg gtgtgattct tttaatccac tgccgctcat
     4681 ttggataaat tgcgcttcat cacgtaattg ctgtagattg gctgccccaa cataacccat
     4741 tcctgaacgc aaaccgccga tcatttggaa aataatatct gcaacacttc ctttataagc
     4801 aacccgacct tcgattcctt ctggtactaa tttatttgct tcattgacac taccttggaa
     4861 gtaacggtct tttgaacctt tttccatcgc gcctaatgag cccatacctc ggtatgtttt
     4921 gaatcgacgt ccttggaaga tttcgaattc acctggtgat tcatctgtcc ctgccaacat
     4981 acttcctagc atcactgcat gtccgccggc agctaatgct ttgacgatgt caccagaata
     5041 tttgatccct ccgtctgcaa taatcgcttt gccatattga cgagcaactg atgctgcatc
     5101 ataaatagct gtgagctgag gtacacctac accggctacc acacgtgtcg tacaaatcga
     5161 tcctggtccg ataccaactt ttacgacatc tacacctgca tcatataaag cttttgtcgc
     5221 ttcagccgtc gcaacgtttc ctgcaatcaa tgttgcatct gcaaaagttg aacggatttc
     5281 ttgaattttt cggatcacac ctgcactatg tccatgagct gtatcgatga tgattgcatc
     5341 tgcccctgct tctaataaag cattcgcacg ctcaaatgta tcgcttgtta caccaacggc
     5401 tgctgctaca agcaatcgac catgttcatc ttttgctgca tttggaaatt cgatcacttt
     5461 ctcgatgtct ttgatcgtga tcaatccgct taaacgacct tcgttatcta cgattggtaa
     5521 tttttcgatt ttatgttttt gcaaaatctt ttctgcatct tttagagagg tacctactgg
     5581 ggcagtcact aagttgtctt ttgtcatcac atcagcaatc ggcatgtgat aatctgttac
     5641 aaaacgcatg tcgcggtttg taattatccc taccaatttt ctgttttcaa gtgtttcaac
     5701 gattggcaca ccactgatac gatatttgct catcaattct tctgcgtctg ctacaagatg
     5761 ctgtggcgtt aagaagaacg gatcaatgat tacgccactt tcagaacgtt tgacttttct
     5821 tacttcatcc gcttgctggc tgatcgtcat gtttttatgg atcacaccta gtccgccttg
     5881 tcttgccata gcaatggcca tcttgctgtc ggtaacagta tccatacttg cactgatgat
     5941 tggaatattc aacttaatat ttttagctaa ttgtacgctc atatccactt cgtttggtaa
     6001 cacgtgactt tctgctggta tcaataagac atcatcaaaa gtaaatcctt ttttcgtgaa
     6061 ctttgtttcc cagttggaca tttttagtac cactcctcta atttagttta tctattaaaa
     6121 taattgattt tttcatttaa gtcaatgatc tacttggaat caagttagct ttctcataga
     6181 ataccaatat aaagcgttta catctgtgta tattaaaaga gattgtaaaa aagctgtcct
     6241 gcatcaagta ataagaacag ccaatcaaaa acagcttctc atgtttttga attggttggg
     6301 tttattaccg cagatgcaaa cttttgaaca ccgtttagtg gagaggctgt gaaaaagctg
     6361 cttagtttcg agtagtaaga aaaattttgt gaaaatggct ttccacattt ttgcataaat
     6421 tggacttaat accgagaaac tggcttttga acaccgttta tcgtaaaaag ggactgtgac
     6481 aagacttttg tcacagtccc ttactattat ttaactatgg ataaacaaaa tgaggttctt
     6541 tactacccct agatatctag caaaatagct gatctttttg ctagtttatc ttcttgggac
     6601 ggataaactt ccaataatcc cgtatttttt cttcaagtag taacggattg ctaaagcagt
     6661 tgccccgata atgataacta ctactggatc taatactgga ttgataactg gtggcaatag
     6721 tgttgtcgca gaaaacagta cgacccaaag aagtgtcgtt ccacctagga taagcaatgt
     6781 cttacccatt cctggtttct tgcttcgatc tgctccggga tattcatatt gatagatgta
     6841 tttgtacatc atataaaaga cccagccacc gattgcagaa cctagaacga gtgtagaaaa
     6901 gccataagct ggcgttgttc cacgtgaaaa caatccggta atcgcaatca tgatacttaa
     6961 tagaccaagc aacagcaacg tattatctaa ccacatcaat aaaggggtgg atgaattttt
     7021 tacttctgct ggcttattga tgattgcttc cgttctttca gagactgtcc caaacaattg
     7081 acgggctgtt cttccgcctt tttgttctgc aactaaagta ggcagaatgt catgaagggc
     7141 ttttactttt tcttcttcag acaaattcgc tgcttctaaa gattttttca aatcaaaaat
     7201 gtactgttga tttcttttgg ttaattttgt ttctaaacta ttgttttctt ttacgattgc
     7261 tcgtaattgt tctggttcca ttatctaata gtcctcctta gccgttcctt ttctcaacgg
     7321 tcgtcacaaa agacattcta ccatattcta cagctagttt gatagccctt ttacacatta
     7381 aagcggaata acattacgtc gccgtcttgt acgacataat cttttccttc taatcgaaca
     7441 cgtccagctt cttttgctgc atgcatgttt ccgtaatgat ccaagtcttc aaaagagaca
     7501 gtttctgcac ggataaatcc gcgttcgaaa tctgaatgga tgattcctgc tgcttgtggt
     7561 gctttgattc cttttttgaa tgtccaagca cgtacttctt gttccccagc agtaaagtaa
     7621 gtagctaagc ctaacaaatc ataagcagca cggatcaact gatccaaacc tgattcttcg
     7681 attcctaaag cttctaaaaa ttccgctttg tcttcttcat ctaattctgc gatttcttct
     7741 tctgcacgag cactgaccac gatcacttct gcattttctt ctgcagcaaa gttgcgcact
     7801 tcttgtacat aatgattcgc gtctgcatct gctacgtcat cttctgagac attggctaca
     7861 taaagaattg gttttgtcgt caataaaaat agtgatttaa cgattttttg ttcttcttca
     7921 gtaaattcga tcgttcgggc agattttcct tcttccagta caggtttgat tttatccagt
     7981 acagctagtt ctgccactgc atctttatct ttggttttag caacttttgc tacacgagta
     8041 tagcgtttgt tgatagattc taagtctgct aacactagtt ccaagttgat cgtatcaata
     8101 tcttctagtg gatcaacacg tccttctacg tgagtaatat tatcatcatc aaaacagcga
     8161 acaacgtgac aaatagcgtc tacttggcgg atatggctta agaattgatt tcccaaacct
     8221 tctcctttac ttgcgccttt tacgattcca gcaatatctg taaattcaaa agtcgtcgga
     8281 acagtttttt tcggatgtac aagttctgtt aagcgttgca aacgccagtc aggtacttct
     8341 accatcccta cgttggggtc gatcgtcgca aagggatagt ttgctgcttc tgctcctgct
     8401 tttgtgatcg cattaaacaa agttgatttt cctacgttgg gcaacccaac aattccagca
     8461 gtcaatgcca taaatttatt cactctttct ctgcattttt ttcaattact ttttttaatt
     8521 tcttttcaaa atctcgacgg gtcatcatga cgatatgtcc gcaattcata catctgattt
     8581 tgatatctgc gcccattcga atgacttccc agcgattcgt ctggcaagcg tgaggttttt
     8641 tcatttcaac gatatcgtgc aagtcgtaca taaaaatagc ctcctttttg tttattcttc
     8701 atcaaattga atattcaaga tatcaagaat tcgagtcaaa tctttttgag aaagatattc
     8761 aatctcgatc ttacctttcc catttttttc ttggatagct acacttgtac caaatttatc
     8821 catcaaacga tcttcgcttt ctcggatata atatggtttt tcctttgcta gccttgggat
     8881 ttttttcttt tcttttccat cattttgatt taactcagaa acaagctgtt ccagttggcg
     8941 gacagttaaa ttttcagtta ctgcacgatt ggctaatttc aagatcaatg ttttattttt
     9001 taaacctaac agcgtacggg cttgtcccat agataaacgc tgatcttgta ccatttcctt
     9061 gacaagatcc ggtaaagaaa gcaagcgcaa ataattggcg atataaggtc tgctctttcc
     9121 taaacgacta gctacttctg cttgtgttag tttcaggttt ttcatcagca tctcatatgc
     9181 ttctgcttct tctaacggat tcagatcttc tcgctgcaag ttttccagca ctgctacttg
     9241 catcatcgct tcttcgtcaa agtctctaac gatagcaggg atcgtttctt tttcagctag
     9301 tttggacgct cgaaaacgtc gctcccctgc aataatctca tatcctttta ctgcggaacg
     9361 gcgtacgatg atgggttgaa agacacctga ttgttcaata gaattagcta gttcctgcaa
     9421 agatacttct tcaaatgttt tacggggctg atacggattt ggtcgcagct cattcaatgg
     9481 tagctggaca acggtatcat cttttacatc caccgtctct aagttttcta aatcttgaaa
     9541 cagtgcatcg attcctcggc ctaatccttt acttttcttc acgacttacc acttcctttg
     9601 ccaatgcttg gtagacttca gctcctcgag aacgtggatc gtagtcgatg atcggttttc
     9661 catgactagg tgcttctgat aaacgaatat ttcttggaat gatcgtttcg taaacttttt
     9721 cgcggaagta tttacgtact tcttctacga cttcatttcc cagatttgtt cgtgcatcat
     9781 acattgtcag taagactccc tcgatctcta attctggatt aaagtgtttt tggactaaac
     9841 gaaccgtatt cagtaattgg cttaatcctt ccaatgcgta atactcacac tgaacaggta
     9901 tcaaaatcga atcacttgct gtaaatgaat tgattgtcag atggccaaga gaaggcgggc
     9961 aatcgatcaa aatataatca tactgactgc ttacttctgc taaagatcct tttaatcttg
    10021 attctcttgc catcattgac gtcaattcga tctctgctcc tgctaattgg agagtcgcag
    10081 gcacaatact caaattttcg tgttcagtga tcaaagttgc ctcatcaatt ggcaattcat
    10141 tgactagaac atcatagatg tctcttgtca catcaggttt tctgatcccg acaccactgg
    10201 tagcatttcc ttgtgcatcc atatccacta gcaatacttt tttgccaagg ctagcaagac
    10261 aagcacctag attcaccgtc gtcgttgttt tgccgacgcc acctttttgg ttcgcaacag
    10321 atattatttg tgccatctct tctcctccta tttgattggc tgcttattag gcagtccggg
    10381 ctttcttggg tatttctttg gggttggttt ctttttttga ataacgatga tatgccgttg
    10441 atcagagaca ttcggcaagg taaccgcctc ttctttgagg aatttaccac ctaataaagc
    10501 aatcgcttgt tttgcttctg tcaattcctc ttcacttttt gctgctttca atgcataaaa
    10561 atagccttct tgtttagcca agggcaaaca caattccgct aacacattca aacgagcaac
    10621 cgcacgagca gtgacaaggt caaatgatgc acgaaagtga ggattttgcc caaatgtttc
    10681 tgcccggtca tgatataagg aagcatcgat tcctaataat cgggttaact cagataagaa
    10741 ggttattcgt ttattcagag aatcaacgat cgttatctgc agttctggaa aggcaatttt
    10801 taaaggtatg ctaggaaacc ctgcccccga accaacatcg cataaagata aaggttgcgt
    10861 aaagtctact tcaaatgcta atgtaagtga atcgtaaaaa tgcttcagat atacgtcttt
    10921 ttcatccgta atagctgtaa ggttcatctt ttcgttccat tcgactaatg tccgataata
    10981 aatagcgaat tgattcattt gatgatcggt aagctctatc cctttttctg ccaaggattg
    11041 gcgaaattct tctggtatca taaatattcc tttcattgtg aaacagcaat tgtttcacag
    11101 attctctccc tactttaacg caaaatctct agacatgcaa tccttccata tggattctta
    11161 aaaatttgaa aagtaagaaa agccgataga ctttttcttt ctagtatgac tcataaaata
    11221 tacacagaag agagaactag ctttgagcaa tttctgcaaa aactagttct ctcttctatt
    11281 tattattacg tattacgctg gttcactgac tttcgcaatc ttcccttgtt cgatatagac
    11341 cattaggata cttaggtctg cagggtttac gccactgatt cggctagctt gggcaattgt
    11401 ttctggttgg attttctgca atttttgttt tgcttctgtt gctaatccgt tgattgctgc
    11461 gtagtcgatg ttttctggaa tctttttcgc ttccatgcgt tttaattttt ctactttttc
    11521 catggctttt ttgatgtagc cttcatattt gatttggatt tctacttgtt cgatttcttt
    11581 tcgtgtcaat tcttcatttt ctggaataaa ccgtagaagt tctgcataag taatctcagg
    11641 acgtcttaaa aagtcgcttg ctagtacacc atcttttaat ggtgccgcat taatcgttgc
    11701 taaaaagtct tggacttctt ctgttggttt gattcgtaca ttcatcaaac gtttgatttc
    11761 ttgttcaact gcttcttttt tcttcaaata attcttgtat tgatcttctt ttactaagcc
    11821 tacacggtga cccatttctg ttaatcgcaa atctgcatta tcatgacgta aaagcagacg
    11881 gtattcagca cgtgaagtca gcaaacgata aggttcgttc gttccttttg ttaccaaatc
    11941 atcgatcatg acaccgatgt aaccgtcact tcgtttgatc actaaaggtt cttttccctg
    12001 aactttcaaa gctgcattga taccggcaat cagcccttgt ccagccgctt cttcataacc
    12061 gcttgtacca tttgtttgtc cagctgtata aagattttca acgactttag tttctaatgt
    12121 cggacggagc tggtgtggct ctactacgtc atattcgata gcatatcctg tacgcatcat
    12181 ttctactttt tctaatccag caatagaatg aagcatgttg acttgaacat cctctggtaa
    12241 agaagtagat aaaccttgaa catagacttc ttccgtattt aagccttctg gttccaaaaa
    12301 taattgatga cgtggtttgt ctgcaaaacg cacgatctta tcttcgatgg atggacaata
    12361 gcgagcgcct accccttcaa cgatccctgt aaacattggg gcacgatgta agttgtctcg
    12421 aataatttgg tgagtcgtct cacctgtata ggtcagccag caagattcct gatctagttt
    12481 ataggcacta tctggtgtgc tgaagctaaa atgattcggc tctttgtcac caggctgctc
    12541 ttctgtaaca gaatagtcga tcgtacttga ttttactcga ggcggtgttc ctgttttgaa
    12601 ccgttcgata gcaaagccaa gttcttttag atgattcgct agtccaatag aaggttgaga
    12661 gttattcgga cctgatgaat atttcaattc accgataatg atttctccgc gaagtgctgt
    12721 tccggctgta ataacaactg ctttggcccg gtagctcgct cctgtggacg tcactactcc
    12781 atgacaaaca ccatcttcga cgatcagttc ttcgacgatt ccttgtctta gcgtcaaatt
    12841 tggttctttt tcgatcgtat gtttcatttc tgttgaataa gcatgtttgt ctgcttgtgc
    12901 tcgcaatgct cggacagctg ggccttttcc tgtgttcaac atacgcattt ggatataggt
    12961 tttatcgata ttcttaccca tttctccgcc taacgcatcg atttctcgaa cgacaacgcc
    13021 tttagctggt ccgcctacag aaggattaca tggcatgaat gctaccatgt ccaaatttat
    13081 tgtcagtaat aatgtttttg atcccatacg tgcagcagca agtgcagctt ctgaaccggc
    13141 gtgtcctgcg ccaacaacga tcacgtcata cgcatctgct tcataatgtt ccaatcgttt
    13201 gttcctcctt ttattttcct aaacaaaatt gactgaataa ttgagtgatt agctcatctt
    13261 gtacactgtc gccgacaact tctcctagat agtcccagca acgcgtcata tctatttgaa
    13321 cgagatccac aggcattcct gaatcaatac ctgcaatgac ttcttcaagt gagagggaag
    13381 ctttttctaa caacgcgata tggcgggtat tagaaacata agtagcgtct ctttctcctg
    13441 tttctccgct gaagaataaa tcagaaatag ctgattccaa acgatctagt ccgtcgtttt
    13501 tagctacgga aattgaaaaa actggttcat tttcgatcaa tttcttcaat ttttcttgtt
    13561 ccagctgtgc tggcaaatct gttttattta gaagaatgat ccgtttcaat ccacttgtcg
    13621 cttccaataa ttgttcatct tctgctgtca gtggttcgct ttggtttaga acaagtaaga
    13681 tcaagtctgc ttctgctaat gcttttcggc ttctttcgac cccgatccgt tccaccacat
    13741 cttctgtttc ccgaattcca gctgtatcga ttagcttgag cggtaccccc cgaacattga
    13801 catactcttc gattacatct cgagtcgttc ctgcaatatc cgtaacgatt gctttttctt
    13861 ctcttaacaa atggtttaac aaacttgatt tgccgacatt tggccggccg atgattgccg
    13921 tacttaaccc ttcccgcaga accttccctt gcttggatgt agcaagtagc gcttggattc
    13981 tttgttggat catctgcgct ttttcaagca ataacttcgt agtcaattct tcgacatcat
    14041 catattctgg ataatcaata tttacttcta cttgtgctaa tgtctctaaa atctcttgtc
    14101 tcaatgagcg gatcaaagca gacagattgc cgtctaactg attaagagct agtcccattg
    14161 ctttgtctgt ttttgcccga atcaaatcca tcacagcttc tgcctgtgaa aggtcaacac
    14221 gaccattcaa gaatgctcgt tttgtgaatt cgcctggctc agctaatctt gcaccttctc
    14281 ttaacaatag ctgcaaaatt tgattgacta caacgatccc accgtgacaa ttgatttcta
    14341 ctacatcttc ccgcgtaaat gtctttggtg ctctcatcac ggagaccatg acttcatcga
    14401 caagctgatt gctcttggga tcaacgatat gtccataatg gatcgtatga cttggtactt
    14461 ctgataatcg tttgtttcca gattgataaa ctttatctgc tagttgcaca gcttgatcgc
    14521 cacttaaacg aacgatactg attgcacctt ctccaggtgg ggtagaaatt gccgcaatcg
    14581 tatcaaattc taaagtaatt tcagccattt tttcacttcc tttttcattt tgcgcacaaa
    14641 aaaagtgccc actccaccct ttatgcacaa taaacggtga acttcgcact ttgactgctt
    14701 gttcttgatt aaattctggt catagattat cacacttgct ataaggaatc aagtgtttaa
    14761 aacaattaga tgaagttgag cctgttctgc ttccattacc ttatatttaa ttgtccttgg
    14821 atgtctcttt gcgttctttg gtttattcga agagaagata ctgtataaac aaggctttat
    14881 ctttcttaaa aaaaacggta cactaaatgg tagcgctatc taaactatac acttttgaaa
    14941 ggagaaaata tgtgagcccg ttcagatctg ctgcattgga agaagaaagt gaccctcgga
    15001 tcaacgatgt cgttttatct acagggaata tcaaccagaa atatatcgtc cgcgatatcg
    15061 tttttgttgt ggaatgctta gaagctgatt tgtttgaccc atcttttccc aaagatgacc
    15121 ttttcttaac aacgaagagg aaattaaaga cgaaggtact tgaatatggt gcgaatgcag
    15181 taatcaactg tcattttgag tatcagcaaa aaaaacgcga cggaaagtat tttctggaac
    15241 tttttgctta tggaacagtg atccaattta tccaaacaac gattggttaa atgaaacaga
    15301 caaaaaaagc ggatcaaaac tgaagacagt ttcgatccgc ttttttctat caaagttagt
    15361 gactacttca tcgtatactc tgataagaat gatttctagt aaaatatact tggtttgaaa
    15421 aactttgtca acgtgattta ttcaaaaagt aatggaatca ataatatttt ttagcaggtt
    15481 ctactactaa ataacgataa ggttcctcac cttccgaatg tgtttttaca tgttcatctt
    15541 tgcttaatgc agcatggatt tgtttacgtt caaatgcagg cattggttct aagaaaacag
    15601 gctgccctgt ccgttttact ttttcagccg tgcgatcagc taaacgctga atgatctctt
    15661 ggcgcttttc acggtaattg cctacattga ctactacaga cagcttattt cttgctaaac
    15721 gatggatgaa gacttgtgcc agatattgca atgcattcag tgtttttcca tgtttcccaa
    15781 tcagtatgcc ttgcttttgt gtttctaaat ggaaaacaac catattattt gattctcttt
    15841 ccattttgac aagagctgga gcatcaagct gttttgaaat ttcagtaaga taaactgcca
    15901 attccgttaa agctgcttca tcacctagct cacttacttc ttctgttttt tcttcaagaa
    15961 tcgtttcgtt gactacctcg atctcagctg ttggttcttc ttccaaaatt tcttctacag
    16021 tctgttctac tgtttcagaa actttttcgc tgatacttgg ctggatcgaa agccgtgcat
    16081 tctttcgacc cattcctagg aaaccttttt ttccttcttc cagtatttcg atttcgactt
    16141 ggtctttggc caaacccaaa tcagccagac ctagttggac agcttcgtct attgttgcag
    16201 cttcataaat cggcattagc attacctccc ctattatttc cgttttttct taggattcat
    16261 tgctttctta agagcacgtt ctctttcgcg gattctccgt gcttcttctt cacgctcttt
    16321 tcgaattttg aaagggttgt tgatcagcag cgtttgtaca acttggaagg cattggaaac
    16381 tacccagtat aatgaaagac cgctggctaa attgacaccc atcactaaaa tcattacagg
    16441 catcacgaaa ttcatgatct tcattgatgc attcgattca atttgactca tgctagataa
    16501 atacgtactt gcaaaagtaa agattgctgc taaaatcggc aaaataaatg ttggatccgc
    16561 gttccctaag ttcaaccata agaaatgccc ttgtttcaac tctggtacac gtgaaataga
    16621 ttgccataac gccatcaaga ttggcatttg tactaataaa ggaagacaac cagcatatgg
    16681 attgacgcca ttttctgcat ataaacgctg ctgctcttct cttaacttac tttgtgtttc
    16741 cggatctctt gaactatatt gttgctgcag tgcttttaat ttcggttgta attcttgcgt
    16801 tttacgcatg ctctttgttt ggaaatgcat caacggcaat aggatcacgc ggatgatcag
    16861 tgtaaataaa atgatcccta tccctgcatt accaaatgac aacgccttga tcgcctcagc
    16921 aaagtaataa acaatataac gatcccaaat tcctgtactc tgtgcgctga cttccccagt
    16981 tccgcaaccg gataagacga tgaccaaact aacgataccg gccatcaaaa gtaaacgttt
    17041 gtatttcttc acttactctt ttcctctctg tcgattattt ttgcaagttt taagacgtgg
    17101 actaaattgg agcgaacctc atcataagtc aaccccttca cacttggtct agcaatcaca
    17161 ataaaatcca actccggatc aatttcttct tttatagaat aaactgctgc tcggattttt
    17221 cgtttgactt cattgcggtt taccgcgttg ccgacctttt ttcctacaga taaaccaact
    17281 cgaaaatgag gctgtcccgg tttttccaaa cggtaaacga cgaatttgcg gttagcaaaa
    17341 gaatctcccg tatggaacac ggcttgaaac tctcgttctt tttttactcg atacgctttt
    17401 ctcattagtt ttctttcctt ttctatctct cacttacgct cataatcata ccataattac
    17461 gattgtcctt tcatcatttc cctaaaaaag agtataaaaa aaaccactga aaccccagtg
    17521 gcctaagctg aaagaacttt tcttcctttg cgacgacggc tagctaacac acgacgtcca
    17581 tttttagtac tcatacgttt acggaatccg tgaacttttt gacgtttacg tttatttggt
    17641 tggtatgttc ttttcatata ttccacctcc aaaatgttct tatctatttt ataaacacag
    17701 acatactttg atagtataac gacaaagtag tgattttgtc aatataaaat agaagatcga
    17761 ttgttaaaac ttatccacaa gattattttt ttctatggga atcctatgtg gaaaaagtta
    17821 tgcacaggga ttatccacag ataataaaag gctggtttta cacagaaaac acacgtgtaa
    17881 aaaaagtaat ccacaatcag gcgatttcct gtgtattccg tctcctaact attggtatat
    17941 ctgtattttt tatccacaga cgcaagagga aatctattgg tttttacgag ttttccacct
    18001 gtgcattagt ggtgtggaaa actttttttg acaactgtgt ttttctcttt tttctttttg
    18061 tcgattgtgt ggataattgt aattaaaaaa tttttttctt cggtttctgt ggaaaactat
    18121 tgaaaaaaat gctaaattag tactagttat tcacttttta atgaaggagg aggccttata
    18181 tggtatccct cgatgcttta tggaatgaat taaaagcaac ataccaaaag gatttatcgc
    18241 ctgctagcta taatacatgg atcgaaacag cgaaccctcg aacccttgat caaaaccagc
    18301 tcgttgttga ggttcctagc aagattcata aagaatattg ggaaaaaaac ctggcgacaa
    18361 aaatcgttga agtcggttat atgttatcag gaaatgagat tatccctcgc tttattactg
    18421 gcgaagaagc agagcaagaa gaagttatag aagaaaaaaa tccaaaagtt gtggcaccta
    18481 gtccgctaaa aaaagccatg ctgaacccta aatatacctt tgatacgttt gtcattggta
    18541 aaggaaacca gatggctcat gcagcagcgc tcgttgtagc agaagatcca ggttctattt
    18601 ataacccgct cttcttttat ggaggcgtgg gacttggtaa gactcacttg atgcatgcaa
    18661 ttggtcatca aatgctgcaa agtcagccta atgccaaagt aaaatatgta agcagtgaaa
    18721 cttttgctaa tgatttcatc aattcgatcc aaaacaaaac agcagaagag ttccgtcaag
    18781 aatatcgaaa tgttgattta ctgctagtgg atgacattca attttttgca gaaaaagaag
    18841 ctacgcaaga agagtttttc catactttca atgccttgta caatgaaggg aaacaaatcg
    18901 tactaaccag tgatcggttg ccaaacgaga ttccgaaact gcaagaacgc cttgtttctc
    18961 gctttgcatg ggggctgtct gttgatatta caccgccgga tcttgaaaca agaacagcga
    19021 ttttacgtaa aaaagcggcg gctgaacgtc tagagatccc agatgacaca ctaagctaca
    19081 tcgcaggaca aattgattct aacattcgtg aattagaagg tgcgcttgtt cgagtgcaag
    19141 cttttgctgc gatgaatagt gaagatattt cgactagtct agctgcagac gcactgaaaa
    19201 cgttaaaatc aggaaaagga catcctcaat tgtcaatcct gcagatccaa gaagaagtgg
    19261 caaagtatta tcacatccaa ttgaaagatc tcaaaggaaa gaaacgcgtc aaatctattg
    19321 ttgttcctag acaaatcgct atgtatttgg cacgtgagct cacagataat tctttaccga
    19381 aaatcggagc tgaattcggt ggcaaggatc atacaacggt tatccatgct catgaaaaaa
    19441 tccagcagct gatggattct agtgtcagta tgcaaaatga agtatcagaa atcaaaaact
    19501 ttttactaaa ttaatttgtc gattctatca actgaaaata gcatgtggat aaaagaaaaa
    19561 aacgttcaaa agttatacac actttttcca cagctgtttt ttcgtttctc tcttacgttt
    19621 tttgagtttt ccacagaatc aacatgccct attactttta ttattctttt taactaataa
    19681 taaataaaca aacattcaaa ggagatacat catgaaagtt actttaaacc gagctagctt
    19741 tatgcaggaa ttgcaaactg ttcaacgagc tatttcaagc aaaaccacga tccctatttt
    19801 gacaggtgta aaaatcacac tgacacaaga aggtttgact ttgacgggga gcaacgctga
    19861 tatatcaatt gaaacttttt tgtctgttga aaacgaaaaa gcaaatatgc aaatcgaatc
    19921 tactggttcc attgttttac aagcacgttt ctttagcgaa atcattcgga gacttcctga
    19981 agaaacattt actttagaag ttttagaaaa taaacaagta gcgatcactt ctggaaaagc
    20041 gaattttatc gtaaatggat tagatgcaga taactatcct catcttcctg ttgtcgaaag
    20101 ccataaccag atgaaattac ctgtacacgt attgactaaa ctaatcaacg aaacagtttt
    20161 tgctgtctca caacatgaga gtcgtccaat cttgacaggt gtgcatttca ttttatctga
    20221 taattcttta ttagctgtag ctactgattc tcaccgtcta agtcaacgcg tgattccagt
    20281 agaacaagcg gctgatcatt ttgatattgt tattcctgga aaaagtttga tcgaattatc
    20341 tcgctcatta acaaatgaag aagaaatcgt cgaaatcagc attatggaaa accaagtgtt
    20401 gttcaaaaca gaaacgatgt atttctattc ccgtttgcta gaaggaaact atccagatac
    20461 caatcgtttg attccttcaa gttttaatac agaggttgaa ttttctgttc ctagcttttt
    20521 agcggcgatc gaacgggctt ctttactttc tcatgaaggc cgtaacaaca tcgttcgttt
    20581 atctattcgt ccagatgcgg ttgttttata cggaaattcg ccagaaatcg ggaaagtaga
    20641 agaaagcttg agttatacag caagcagtgg cgatccatta gatatttctt tcaatccgga
    20701 ttatatgaaa gcagcgttgc gtgcatttgg agatatgagc atcaaagtga aatttatctc
    20761 tgctattcgt ccatttacat tggaaccaac ggaagatggc gttcaattta ttcagctgat
    20821 tactcctgta cgtacaaatt aacaatgatt ttcaatgttc ttgaaaattt aattgaaaag
    20881 aaatagaaaa aataaaattt taaacagaag gccctaaaat ctcttttaag gctttctgtt
    20941 tatttttgtt taaatcacct tttttagatt aaatcgtctt atatggaaaa atatatggat
    21001 aaatttgttt tattgcgaaa aaaaaggtat aatagagtat acttttaata atgaaaatga
    21061 gggatgggca ttgaaacaac aagtcattct aaatacggaa ttcatgacgt tgggccaaat
    21121 gttgaaagaa gtcacagtta tcggtagtgg cggacaagca aaatggtatt tggcagaaaa
    21181 cactgtgtta gtcgatggcg aaccagaaaa tcgtcgtgga cgcaaacttt atcccggcat
    21241 gatggttgaa gttccagaag taggaacttt ttttatggta aaaaaaggaa acgacgataa
    21301 tgaggctgaa taagctgtat ttaaaaaatt atcgaaatta cgaagagctg aacatcgaat
    21361 tttccaagaa cctcgtcatc tttttaggag aaaatgcgca aggaaaaacg aatcttttgg
    21421 aaagtatcta cgtattagct atgacgcgaa gtcatcggac aagtagtgag caggaattga
    21481 ttggctggac tgacgatcag gcgatgattc aaggagagat cacaaaaggt tcatccactc
    21541 ttccattaga aatcttatta tctaaaaaag gccgaaaaac caagatcaac catatcgaac
    21601 agaaaaagtt aagtacttac gtgggacaaa tgaatgtcat tttatttgca ccagaagatc
    21661 tttctttagt aaaaggcagc ccgcagacca ggcggaagtt tttagatatg gaattaggcc
    21721 agatcaatcc aatctatctt tatgatcttg tccaatacca agcaattttg aaacaaagaa
    21781 accagtactt gaagcaattg aatgaaaaaa aacaaactga tttgctttat ttggatattt
    21841 tgtccgaaca actagcagcg tttggcagca aagtattgaa agcaagagca cagttcgtca
    21901 agcgattgga gttttgggct aattctttgc atcagcaaat cacccatcaa aaagagcagc
    21961 tggaaatcga gtatctcacc gcagtcgatt ctttagaaac acatacgcaa gagcaaatcc
    22021 aagaacaatt tctcgcactt ttgaaccaaa ataaaaagaa agaccttttt cggggaacaa
    22081 cgacagttgg tcctcatcgt gacgatcttt ccttttttat taatcagaaa aatgtgcaga
    22141 cttatggatc gcaaggacag caaagaacaa ctgcactaag tgtcaaatta gcagaaatcg
    22201 atttgattaa agaagagaca ggggaatatc caatcctttt gttagatgat gtgatgagcg
    22261 agctggatga taatcgtcaa ctccatctgc tagaaacaat cgaaggaaaa gttcaaacgt
    22321 tcttaacaac aacgacactt gaccatgtaa aaaataaaat gactgttgaa cctgagattt
    22381 tttatgttca acaagggaaa ctaaaaggag aagaaactga atgacagaag aaagaagttt
    22441 agtagaacgc gctaaagagt atgatgccag tcagattcaa gtacttgaag gacttgaagc
    22501 cgttcgtaaa cgacctggca tgtatatcgg ttcgactagt tctgagggtc tgcatcacct
    22561 tgtttgggaa attgtcgata attcgatcga tgaagtatta gcaggttttg caacgaaaat
    22621 ccatgtgatt attgaaaaag acaacagtat caccgttatt gacgacggtc gggggatacc
    22681 tgtagatatc caggcaaaaa ctggacgtcc tgcagttgaa acggtcttta ctgttttaca
    22741 tgctggagga aaattcggcg gtggtgggta caaagtttct ggtggacttc acggagtagg
    22801 atcttctgtt gttaacgcgc tttctacaca gcttgatgtc aaagtataca aagaaggaaa
    22861 tgtgtactat caagaatatc gtcgtggagc tgtagtggac gacttaaaga ttatcgaaca
    22921 aacggatcgc catggaacaa cggttcactt tacgccagac cctgaaattt ttacagagac
    22981 aactgagttt gatttttcaa aattggctac ccggatccgt gaacttgctt tcttgaaccg
    23041 cgggatgcgt atatcgattg aagacaaacg agaagaagaa ccagtcatca atgaatacca
    23101 ttatgacggc gggattaaaa gttatgtcga atacttgaat gcaaacaaaa ccgtgatttt
    23161 tccagaacct gtatatttgg aaggtgaaca gcaagatatc gcagttgaag tctctatgca
    23221 atatacagac ggctaccatt ccaatatcat gagttttgcc aacaatatcc atacgtatga
    23281 aggcggaaca catgaatcag gattcaagac tgctttaact cgtgtgataa atgattatgc
    23341 ccgaaaacaa aagctgatga aagaaaatga cgacaacttg accggtgaag acgtgcgaga
    23401 aggattgaca gctgttattt ctatcaagca tcctgaccct caattcgaag gacaaacaaa
    23461 aacaaaattg ggcaattccg aagtacggac agtcactgat cggttattta gcgaacattt
    23521 catgaaattc ttgctggaaa acccaagtgt gggccgtcaa attgttgaaa aaggattact
    23581 agcttccaga gctcgtctag cagcgaaacg tgcgcgtgaa gtaacgagac gtaaaggtgc
    23641 tttagagatt agtaatctgc caggaaaatt agcggactgc tctagcaacg atcctgaaaa
    23701 atgcgaattg ttcatcgtcg aaggagattc ggccggcgga tcagctaagc aaggtcgtaa
    23761 tcgagagttt caagccatct tgcctattcg tgggaaaatc ttgaatgttg aaaaagcaag
    23821 catggacaag atcttggcaa atgaagagat ccggtcttta tttactgcta tgggtacagg
    23881 gtttggagaa gattttgatg tatcgaaagc tcgctaccac aaattagtta tcatgactga
    23941 tgccgatgtc gacggcgcgc atatccgtac attgctgctg actctttttt atcgttacat
    24001 gcgtcctatt gttgaagctg gatacgtcta tattgctcag ccacctttat acggggtaaa
    24061 acaagggaag aatattacgt atgtacaacc aggaaaaaat gcagaagaag agttgaaaca
    24121 agtcgttgct tcacttcctg cctcaccaaa accaagcgtt cagcgttata aaggacttgg
    24181 agaaatggat gatcatcaac tatgggaaac aactatggac ccaagcaatc ggatgatggc
    24241 ccgcgtcagt gtggacgatg ctattgcagc agatcagata tttgaaatgt tgatggggga
    24301 tcgagtagaa ccccgtcgtg cattcatcga ggaaaatgca cactatgtga agaacttaga
    24361 tatttaatca tgaaggagga aaaagaatga gtgaagaaat cagagaaaac atccatgatg
    24421 tcaatctaac cagcgaaatg aaagactcct tcatcgatta tgcgatgagt gttattgtcg
    24481 cacgtgcact tcctgatgtc agagatggtc tgaaacccgt tcatcgccgt attttatacg
    24541 gcatgaacga attaggtgta acaccggata aagcccataa aaaatctgcc agaatcgtcg
    24601 gagatgtcat gggtaaatac catcctcatg gagactatgc gatctatgag tcaatggtac
    24661 ggatggcaca gccattcagc taccgttata tgctagtgga tggtcatgga aactttggtt
    24721 ctgttgacgg tgacggtgcc gccgctatgc gttataccga agcacggatg agcaaaatcg
    24781 ctacagaaat gctgcgtgat atcaataaga acactgttga tttccaaagc aactatgatg
    24841 atacagaaaa agaaccagtt gtactacctg ctcgcttccc gaatctttta gtgaacggaa
    24901 caacggggat cgccgtaggt atggccacga atatcccacc tcataacttg tctgaggtag
    24961 tagcggctat cgatttgctg atggataatc ctgatgtgac gaccaatgaa ttgatggaag
    25021 tattacctgg accagatttt ccaacaggtg gtttggttat gggaaaatca ggaatccgaa
    25081 gagcgtatga aacaggtaag ggttctatta ccgtacgtgc aaaagttgag attactgaga
    25141 tgccaaatgg taaagaacgg atcatcgtga cagaattgcc ttatatggtc aataaagcaa
    25201 aattgatcga acggatttct gaactgcaca gagacaagcg tatcgaaggg atcacagatt
    25261 tgcgggacga atcttcccgt gaaggtatgc ggatcgtcat tgacatccgt cgtgacgcca
    25321 gcgcatctgt tatcttgaat aacttatata aattgacatc cttgcaaaat tcatttggat
    25381 tcaatatgtt ggcgatcgaa aaaggtgtgc cgaaagtttt gagcttgaaa caaattcttg
    25441 aaaactatat cgaacatcag cgcgaagtca tcacaagacg gacagtcttt gaaaaagaaa
    25501 aagcagaagc aagggcacac attttagaag gtttgcgtat tgctttggat catatcgatg
    25561 aaatcattgc gattatccgc gggtctaaat cagatgacga agcaaaagcg acgatgatcg
    25621 aacggttcga tttatccgat cgccagtctc aagctatttt agatatgcgt ttacgccgat
    25681 tgaccggttt ggaacgggaa aaaatcgaaa atgaatacca agaactctta aaactgattg
    25741 aagatttaac tgacattctg gcaagaccag aacgtgttac agaaatcatc aagaatgaat
    25801 tagcagactt gaatcaacga tttggtgata aacgacgcac agaattacta gtcggtgagg
    25861 tcttaagtct ggaagatgaa gatttaatcg aagaagaaga aatcgttatt acattgacaa
    25921 acaatggtta catcaaacgt ttggcaaata atgaattcag agctcaacga aggggtggac
    25981 gtggtgtcca aggaatgggt atccacaatg acgacttcgt caaaaatctg gtttcttgtt
    26041 ctacccatga tacattgtta ttctttacga ataacggaaa agtgtatcgg gcaaaaggat
    26101 acgaaattcc agaatacggg cgcacagcca aaggaatacc aattatcaat ttactaggta
    26161 tcgattcgag tgaaagcatc caggcaatca ttgcggtgac gggagaagca gaagaaggcc
    26221 actatctctt ctttacgacg cgtcaaggta cagtaaaacg tacttctgtc actgcttttg
    26281 ctaacatccg aagtaatggt ctgatcgcaa ttggtttgaa agaagacgat gagctcgtca
    26341 atgtgctact gacagatggt caatctaata tcattattgg aacacataac ggctactctg
    26401 tcactttcaa agaagaagca gtccgcgata tgggacgtac agcttccggg gttagaggaa
    26461 tacgcctgcg tgaggaagat tatgtcgttg gggcagcctt aatgaaggaa gatcaagaag
    26521 tattagtgat cacagaaaaa ggttacggaa aacggacaaa agtatcggaa tatccagtga
    26581 aaggccgcgg aggtaaaggg atcaaaacgg cgaacatcac tgaaaaaaat ggtccactag
    26641 ctggattgac cactgtttct ggagatgaag acatcatgct gattacagat aaaggtgtca
    26701 ttatccgttt caacgtatcg actgtttctc aaactggacg ttcaacatta ggcgtacgtt
    26761 tgatgaagat ggaagctgat acgaaagttg tcacgatggc agcagtcgaa ccagaagctg
    26821 cagaacaaac agttgaagaa caaggatcag aagaatagcc atcaagacta attgtgtaag
    26881 ctagcaagaa tgaccgatta aaaaatctgg ttattcctgc tggctttttt gattagttga
    26941 atttctctta aaatattcga aactgttcat tctgtattgc ttttgaccaa aatagagtgt
    27001 ataatcagag cttgtgagta gtctaattaa ttagataact ctccttgctc ttaggaacct
    27061 aagagccgaa agtccacagg gaggtgaata tcaatggaaa acacgaaata tgaaatcatg
    27121 tacattattc gtccaaacat tgatgaagaa gcaaaaactg ctttaatcga acgtttcgat
    27181 gcaatcttga aagataacgg agcagaagtt atcgaatcaa aagattggga aaaacgccgt
    27241 ttcgcttatg aaatgaacgg ttaccgtgaa ggtatctatc acatcgttaa agtatcttct
    27301 ccatcatcag caaatgctgt caatgaattt gaccgtcttg ctaaaatcaa cgacgatatc
    27361 attcgtcaca tgattgttaa agaagaagct taattgttgt ttcatgtgaa acaatagaaa
    27421 acgatgagag gagatgacta ttttgattaa taatgttgta ttagttggac gtctgacgaa
    27481 agatccagat ttgcgttaca cagcaagtgg tacggcagtc gcaacattta ctttggctgt
    27541 gaatcgtaat tttacaaacc aaagcggcaa tcgcgaggct gattttatca actgtgtgat
    27601 ttggcgcaaa tcagcagaaa ctttagcaaa ctatgctcgt aaaggaacac ttttaggtgt
    27661 tactggacgt atccaaactc gttcttatga taatcagcaa ggacaacgtg tatacgtgac
    27721 agaagtagta gctgacaact tccaattgct ggaaagtcgt tctgcatctg aaaatcgcca
    27781 acaaagcggc ggattccaaa gttctggtca atcagctggc ggatttggcg gaaacaataa
    27841 ctctaatcaa acatctcaat catccaacgg tatgcctgat ttcgaccgtg atacttctga
    27901 cccattcggc tcaagttcaa cgatcgacat ttcagacgat gatttaccat tctaaacgaa
    27961 tttgatagga gggaaataga atggcacaac aaagaagagg cggacgtaaa cgtcgtaaag
    28021 tagactacat tgctgctaac catattgaat atatcgatta taaagatatc gaattactaa
    28081 aaagatttat ttcagaacgc ggtaaaatct tgccacgtcg tgtaactggt acaggcgcta
    28141 aaaaccaacg taaaattact gttgcaatca aacgcgctcg tatcatgggc ttgctacctt
    28201 tcgttagcga agactaataa atcctaggaa ttgaatgact gatccttttg atcagctatt
    28261 caattccttt ttttctgtaa aaataacctc tattcgttta gtcgctcgaa tgacgaaagt
    28321 tatggtaaaa tcaaattagt catatatggg aggaaaatta tggaaaataa aaacaatcat
    28381 ttatccccga aacctctctt ccttatcctg tttatattaa tcgaagtatt ggtagtctta
    28441 attttaccat ttcgttttgt tagcgcttcg gtcattctat tgatgaattt atggggtgtt
    28501 cgctattggt tgaaaatgaa acgttggctt attttaaata aacgtgaaaa aatccagcag
    28561 gcttcgactg tagctgaaac caatctagct tatgtctcag aagtcatgcc tgtaggagtg
    28621 attgcttatc agccatcaag ccaaaaaatc gaatggctca atccattagc attgaaaatc
    28681 aaagatcaaa gtggattaac agaggaagaa ttgctagata ctttttttac tgcaaaagaa
    28741 aaaaagaaaa accaagtcta tctagcagat aaaacatttc agtttgatat ggatacagta
    28801 aagggtgttg tttattttaa tgatattacc caaaaccagt tgttaaaact ccatcagacg
    28861 aacagtcagc cggtgattgg tattttatct attgataact atgcagatgc cattgataaa
    28921 ttggatgaca aagagatttc ttatttgaac tctttcgtca ctacactagt ttctgactgg
    28981 atgaatgaat accatgtctt tttcaaaaga atcaacgcag aacggttttt cttcgtagca
    29041 cagatgatcg atctgaaaaa gatgatggat aaaaaatttg atttgctgga tcgctttcga
    29101 gcagaagctg aaaaacagag ctcgcctatc acccttagta tggggattgc ttatggctca
    29161 agaaccctcg atgaaatcgg tggagaagct cagaataatt tagatgttgc tttagtccgt
    29221 ggaggcgacc aagttgtcgt gaaagaggta aaagaaggag caaaacctgt ttattatggg
    29281 gggaaatctg ctaagaatgt caaacgcacg cgtgttcgtt ctcgagcgat gagtaccgct
    29341 ttgcgtcgga tttttgatga aacaggcgat gtgtttatca tggggcacaa gtttccggat
    29401 atggatgctt taggctctgc ttttggtgtc agttgtctgg cacgcttcaa ccagaaaaaa
    29461 gcttacatcg ttatcaacga gaacgagatc attccagatg tagaacggtg tcttgaagaa
    29521 atccataagc atcctgaatt agaaatgcaa ctaatctctc cagaacgtgc catagagctg
    29581 aaaaaagaag aggacctcct cgtgatggtg gattaccata aaccttctct atcgatctct
    29641 cagggcctat atgagcaatt tgataagatt gtgatcattg atcaccatcg tcgtggggaa
    29701 gagtttccaa gtaaacctct gctgacttat atcgaatctt cagcttcttc agcttcagag
    29761 ctagtttctg agctgatcca ataccaaagc agcaaaacaa atcgcttaga tcgttttgag
    29821 gccacattat tgcttgcagg gatggttgta gatacaaata gtttcaatgt ccgtacaact
    29881 gcacgaactt ttgacgttgc cagctattta aggtcttgtg gagcagacgc atccttagta
    29941 caatatttat tgagctcgga tttagcgaca tacttggaga tcagcaattt gattgctgga
    30001 agcgactatg tgacttctga tattgttgtg gcggcaggga cagacgaaaa agagtataat
    30061 agtgttatag cagcaaaaac agcagataca ttgctttcga tgatcaatat caatgcagct
    30121 ttcgtcatta caaagcggac agacggcttg attgggatca gtgccagaag taccggcacg
    30181 atcaacgtcc aaatcatcat ggaatcctta ggtggcggag gacacttcac aaacgcagct
    30241 actcaactgg aaaatacgac agttgaggaa acaaaacaga agctatttgc tgcaatcaaa
    30301 gaaaatatga atcaaatata tgataaggag taatccaaat gaaagtaatt tttttacaag
    30361 atgtaaaagg aaaaggtaaa aaaggggaca tcaaagaagt tccagcaggt tatgcacaaa
    30421 attatctaat caaaaataac ttggcaaaag aagcaacgaa aagcagtatc agtcagttag
    30481 caggacaaaa gaaagcacaa gaaaaacacg aagctgaaat cttggaagaa gctaaaaagt
    30541 taaaagaatt cttggaaaaa gaagatactg tagtcgaatt gaaggcgaaa gcaggggaag
    30601 acagccgttt gtttggttcg atcccttcaa aacaaattgc tgaagggtta aacaaacaat
    30661 acaaaatcaa attagataaa cgaaaaatcg aattagaaaa tccgatccgt tcactaggct
    30721 acacaaacgt acctgttaag cttcatcatg aggtgacggc tacgatcaaa gttcatgtcg
    30781 tacaagaata acaaatcttg atagcgatgt tcagctggta agtataacca gaaggaaaaa
    30841 agacaaaccg aaatttatct gagaaaacag ctgcagcaat gaaagcaaaa gctgcaaatc
    30901 gatttcagat tgatttcggt ttcttttttg ggaacagcaa aatagcataa agaaaacgag
    30961 tataataaaa gagaactatt tttttattac actttcggta cgaatgatga cttttctctc
    31021 attttcttgt aaaatgaagc aattgaagac aaggagcgat acgtatgaat gaagtgtggc
    31081 aggatcgaat cccaccgcaa aatattgaag ctgaacaagc ggttttaggc tctgtttttc
    31141 ttgacgcaga aacgatcatt gatgccatgg agtacataga gccaaaagac ttttatcgtc
    31201 gtggccatca aattattttt gagacaatga tcgagttaaa tgatcgtaat gaagcgattg
    31261 acgtggttac tgtcaaagac cggctggaac aagccaattt gttagaagat gccggtggtt
    31321 taagttatct ctcagacttg gcattagcag ttccgacagc agcaaatatc gtctactatg
    31381 cgaaaatcgt tgaagaaaaa tcattgctgc gtacattgat ccagacagca acaggaatcg
    31441 ttacgaaagg attcgagcaa ggagaagaag ttcaaacaat tttagatgat gccgaacgca
    31501 gtatcttgga ggtttcggaa aaaagaaatc gaagcggctt tttatctatt gctgaagtac
    31561 tgaactccac gattgaaaat atcgatcgac tagctcaaaa caatgaagaa atcacaggtc
    31621 taccaactgg ctatcaaggt ctggataaaa tgacagcagg tttccagccc gaagaactaa
    31681 tcattcttgc tgcacgtcca gcggtaggta aaacagcgtt tgcattgaat attgctcaaa
    31741 atgtaggaac aaaaacagat cgttctgttg cgatatttag tttggaaatg ggggcagaat
    31801 ctcttgtaaa tcggatgctt tgtgcagaag gttcgattga ggccagccat ttacgtacag
    31861 gtcagctttc ggaagaagaa tggtcgaatc tgatcgttgc gatggggagt ctttctcgag
    31921 caaatatttt tatcgatgat acaccaggga tcaaaatctc tgaaatccgt gcgaaatgtc
    31981 ggaaactagc gcaagaaaaa ggcaatctag gcttgatatt gatcgattat ttgcagttga
    32041 ttgaaggtaa cggtaaagag aaccgtcaac aagaagtatc agatatctct cgccaactga
    32101 aaaaactggc gaaagagctg aaagtacctg tcattgctct ttcacagtta tctcgtggag
    32161 tagaacagcg acaagacaaa cgaccagtgc taagtgatat tcgtgaatcc ggatcaattg
    32221 aacaagatgc ggacatcgta gccttcttgt atcgagatga ttattatgaa agagaaggcg
    32281 gagatgacga tgatggaaac gagccaaaaa atgacaacgt catcgaagtc atcatcgaga
    32341 agaaccgaag cggtgcacga ggaacagttg aactactgtt tatcaaagaa tacaataagt
    32401 tttcgtcgct ttcgccaaga gaagaatttt aaagaagagg ttgtgagcct tgagcaatcc
    32461 cgagagctct cgtaagaaga tgcaaggagt aaccgcagga acgactagag tacttaattt
    32521 aaacagatct ccaaagggat tgtgacaaaa gtcttgtcac agtccctttt tccgaataaa
    32581 cggtgttcaa tcagctgacc cttggtatta gctcagcaaa cgtcaaaata tgaggaacta
    32641 ttttgacgtt tgtttctcta atactcaggt caaaacgctg atcttacgac ctcttttcct
    32701 taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatcatca aacatgagaa
    32761 gcagtttttt gaaattgctc cttgtgactc agagttaaac ggcaggctca caacctcttt
    32821 cttaaacggt gttcaaaagc ttgcatctgc ggtaatacgc ccaatcaaac gaaaaatatg
    32881 agaagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt ttcacaacct
    32941 ctgattcacg gtgttccaaa agtagcttct tcgaaaaata agtcgaaatt tcacaaaaat
    33001 ttgagaagca attttcgtac attccttctt atttcttgaa gctgaccact tctgttacaa
    33061 cctctttttt aataaccatt ctaaaaagat aaagttcgtt ttttaagcgt ttttataaaa
    33121 taaaaataaa aatcattcga ttttatttga aatatgtatc tattattgat acaatggttc
    33181 aggattaaat aatatagaac gaggtgttca catgtcatct gtagtagtag taggtacgca
    33241 atggggcgat gaagggaaag gaaaaatcac agactttctc agtgaaaatg ctgaagtgat
    33301 tgcacggtac caaggtggcg acaatgcagg gcacacaatt aagtttaacg gtgtgactta
    33361 taaactgcat ttgattcctt ctgggatttt ttataaagac aagatcagtg tgatcggaaa
    33421 cggcgttgta gtcaatccta aatcattggt taaagaatta gcttatttac atgaaaaagg
    33481 tgtagaaaca agtaatttgc gtatttctga ccgcgcgcac gtaatcttgc cttatcatat
    33541 caaattggac caattacaag aagatgctaa gggcgaaaat aagattggta caacgattaa
    33601 aggaatcgga cctgcctata tggataaagc agctcgtgta ggtatccgta ttgcagactt
    33661 attagataaa gaaatttttg aagaacgtct tcgtttgaat ctagatgaca aaaaccgtca
    33721 atttgtaaaa atgtttgatt cagaaccact tgattttgac gatatttttg aagaatatta
    33781 tgaatacgga caacaaatca aacaatacgt cacagatact tccgttatct tgaatgatgc
    33841 tttggatgca ggcaaacgcg tgttgtttga aggcgcacaa ggtgtaatgc tggatatcga
    33901 ccagggaact tatccttttg ttacttcttc taacccagta gccggtgggg taacaatcgg
    33961 aagcggtgta gggccttcaa aaatcaataa agttgtcggc gtctgcaaag cctatacgtc
    34021 acgtgtcggt gatggaccat ttccaactga attatttgat gaaacaggag aacaaatccg
    34081 cgaagtagga cgagaatacg gtacgacaac tggtcgtccg cgtcgtgtag gctggtttga
    34141 ttctgtagtt atgcgccatt ctaaacgagt ttcaggtatt accaacctat ctttaaactc
    34201 gatcgatgta ttaagtggat tggaaacagt aaaaatttgt acggcttatg aattagatgg
    34261 cgaactaatc taccactatc cagcaagctt gaaagagttg aaccgctgca aaccaatcta
    34321 tgaagaattg ccaggctggt cagaagacat tacaggatgc aaaacacttg cagaactgcc
    34381 agaaaacgca cgtaactatg tacgtcgtat ctcagagctt gttggtgtac gtatctcaac
    34441 attttctgtc ggacctgata gaacacaaac aaacatctta gaaagcgtct gggcgcaaat
    34501 ctaaggataa aaacgacgac tgaatcagga cgttcttacc agagcgagtc gaagtgttta
    34561 tctatacgat aataataact tgaacactgt ttattcagaa taagggactg tgacaaaaac
    34621 cgtgtcacag tccctttttc cgaacaaacg gtgttcaaaa gcttgcatct acggcactaa
    34681 gcccaatcag atgaaaaata tggagtgcta tttttatctg attgttctta ctgcttgatg
    34741 cagagcagct ttttcacaac ctctccacta aacggtgttc tcctgccaac tcctcggtca
    34801 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    34861 gagctaaacg gcaggctcac aacctcttgg taaacggtgt tcaatcagct gaccctcggt
    34921 attagctcaa aaaacggcaa aatatgagga actatttttt ccgttttttt ctctaatact
    34981 caggtcaaaa cgctgatttc acaacctctg attcacggtg ttccagaagt agcttctacg
    35041 gaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    35101 cttgaagctg accacttctg tcacaacctc ttattttgat tagaacttgc gaaaataaac
    35161 cggttaaagt gtgtctagcg caagagattt gctataatag acgataaggg taaaatgtaa
    35221 cgagaagggg ttgaaaaatg tgtatcaaat tgtaacagat tcttgttgtg atctgccata
    35281 ccatgtatta gcaaaagaaa aagttgattt tttatcaatg aatctccaat tgaatgatca
    35341 agagttagta gatgacctcg gaaagacatt caattatgac cgctacatga atcagctgaa
    35401 aaatggtgcg atgcctacga catcacaaat caatgttggc cgatatttag aatttttccg
    35461 ttcttatgcg gaaaaacaga ttcctgtttt atatgtggct ttttccagtg gattaagcgg
    35521 ctcttacagt agtgcgcttc aagcggttga attgctgaag gaagaatatg aagaccctga
    35581 gatctatgtt tttgatacaa aagctgcaag tattggggaa gggcttttag tattggaagc
    35641 tgtaagattg aaaaaagaag gtaaaagcat cgaagaaacc ctagagtggc tggaaagtaa
    35701 ttatttgaaa gtccattcat gggtaacagt agacgatctg aaatatctag aacgaggcgg
    35761 taggatttcc aaagcaagtg ctactcttgg cagtctattg agtgtaaagc ctattattac
    35821 ggtggataaa gaaggaaggc tgacgaatgt tgacaaagtt cgaggaagaa acaagtcgat
    35881 ccagacaatc gtcaatgaga cggtaaaaac aatcgttgca ccacttgatc aaatcgttta
    35941 tgtggcttac gctggggatc tagagagcgc ggagaaggca aaacggcttt tggaagagca
    36001 gataaagatg aaagatgtga agctttatcc cttaggacca acgatcgcca gtcacacagg
    36061 ctatggctgt atcgcgattt tttcgatggg aatcagtcga taaaagcagt aactcattct
    36121 gtaaaaaagc ccagaaattg attgtaacaa aaacagcgac tcttaaaaga tagatgagca
    36181 tcctatctct tagaggtcgc tgttttttta ttttttaagc taaataggcc attatgccca
    36241 taactcgttc aattgttttt gaatatctgc attttccaaa aattcatcat atgtcgtatc
    36301 agctcgatcg atcacacctt tatccgaaac ggcaatgatg cggtttgcca atgtttggat
    36361 aaattgatgg tcatgtgacg caaataagat tgagccagta aatgccatca agccgtcatt
    36421 caatgctgtg attgattcta agtctaaatg gttcgttgga tcatctaata caagtacgtt
    36481 agctttcgaa agcatcattt ttgaaagcat gcaacggact ttctctccac cagataaaac
    36541 attcactggt ttcaatactt cttcaccaga aaacaacatt cttcctaaga agcttcttaa
    36601 gaaggtgtta tcatcttctt ctttacttgc atattgacgc aaccagtcta aaatcgttag
    36661 atcagtatcg aattctttcg ttgtatcctt tggtaaataa gaattacttg ttgtcacacc
    36721 ccaacgtact gttccagtat ctggcgtaat ttcacccatg ataactttga atagcgttgt
    36781 tgttgttata tcattttctg cgacgaaagc gaccttgtct tctttgctca aattaaaaga
    36841 tatatcatct aaaattttct ttccatcaat cgttacactt acattttcta cctgcaataa
    36901 gtcgtttcca atctcacgtt caggtttgaa tccaacgaat ggataacgtc tagaagaagg
    36961 ttggatatcg tctaaagtaa ttttttcaag cattttttta cgtgaagttg cttgttttga
    37021 ttttgatgca ttcgcactaa agcgggcaat aaattcttgg agttctttga tttgttcttc
    37081 ttttttggca tttgcgtttg cttgaagttt agccgctagt tgactagatt ccaaccaaaa
    37141 atcataattt cctacataaa gtttgatttt accaaaatct agatccgcca tatgtgtaca
    37201 tactttgttc aaaaagtgac ggtcatggga tacaacgatc acagtatttt caaaattgat
    37261 caaaaattct tccagccaat tgatcgattg gatatccaga ccgtttgttg gttcgtctag
    37321 caaaagaaca tcaggtttac caaatagtgt ttgtgctaat aacactttta ccttttgtcc
    37381 accagttaat tcactcattt gctgatggtg caattcttca gggatgttca gaccttgcag
    37441 taaaacagct gcttctggtt cagcttccca tccattaagc tcagcaaatt ctccttctaa
    37501 ttcagctgct cgaataccat cttcgtcagt gaaatcctct ttcatgtaaa tcgcatcttt
    37561 ttctttcagc acttcataca gacgcttgtg tcccatgatg actgtttcaa gtacagtata
    37621 gtcttcatag tcgtaatggt tctgtttcaa tacggccatc cgttcatctg gtcccatagt
    37681 aacggaacct gtggaaggct gcagatcccc tgataacact ttaaggaacg ttgatttacc
    37741 tgcaccattt gcaccaatca agccatagca gtttccgggg gtaaatttaa tattcacatc
    37801 atcaaatagt ttgcggtctg aaaagtgcaa actcacatca tttacagtaa tcaatttttt
    37861 tcctcacttt tatcattatt agttttgaca agtcttatag aattatatag gggaaaggta
    37921 aaagattcaa ggcaatcgaa cattctttgt gtttcacgtg aaacagaatg aaaaaaataa
    37981 aaataaaagc ggagcgaaaa tagctactat aggatttatt agtttgcaac agcataattt
    38041 ttgacgttat ttataagagg gagtactata aaactgtaaa agaaatgaaa gaaggattga
    38101 aaatggatga aaaaagaacc atcgactggg gctcattgat tttgggaatt ttatttgtac
    38161 ttgtctcatt gttatcattt caagaccctg tcggaaattt agttgcaatt gtagtagtct
    38221 ttgcgatttt tgcctttatt aaagggatat ttgaactgtt tgtacggaac agattaaaag
    38281 agctaacagg atataaagga aagatgccct taataatcgg gatcatcgat attctagttg
    38341 gcgtcttttt cttattcaat attggtgcag gagtcgcagc attgcctttt gtttttgcag
    38401 tatggtttat tgctgattca gttttagcgt tatttactgc tgacttggca agaggagtaa
    38461 gtgaaggata ttattggttt acgatcatcg tcaatatttt aggaatttta ttaggaattt
    38521 tcttattgtt taatccaatt tcttctgcgt tgacattaag ctttttagtt ggattctatt
    38581 ttatgttatt tggtatcaca catatcgtct atgcatttag ataagtaaaa tcaaacaaat
    38641 aaaaaagccg gcttccgatt acagttttac tgttgtaatt ggaagccggc ttttttatca
    38701 tggacaaata tgcacgaggt gatttttagg tgtcgagaca aatttatgca aaaatgtgag
    38761 aagctatata cacaaatttt atcttaatac tcgaagcata gcgcagttgt cacaacctct
    38821 tttcatataa ttcattcaat actggcaaat catggacttc atatttttct ttgaatgctt
    38881 ggatttcttc ttcagaatat tttcttggat ctaaatgcag atcttctact ggcaatgggc
    38941 gcttgttatt gatcttcaca tcgattacta caggacgatc tgattttgca gctgcatcaa
    39001 aggcaaatcg aagttgcgag tattctgtga ctgtaaagct atttgccccg agcgcttctc
    39061 caactttacc gaaatctgca tcttctaaaa atacaccaaa tttcttttgt tccgtatctt
    39121 cttgttctgc ttcgatgaaa ccaaaagaat cattcgaaaa gacaacatta ataattggaa
    39181 gctgatattt gacttgtgta atgatatctt gcatgaccat agcaaacccg ccatcaccac
    39241 ttaaggtaaa tacttgtttt tctgggtagc ttagttgtgc ggcaattcct cctggcacac
    39301 cattacccat agttgcgaac catccagatg tcgtatgttt ttgtttaccg ttcatattca
    39361 ataaacgaat agaatggata gtcgtgttac cgacatctgt gacgaaaatc gcatcgtctt
    39421 cagcaatacg attgatttct ttatagacag cctctggacg aatcggttct tcctctcgat
    39481 cttcaaaaga tttcaaccaa tttacccatt tttctttatt ttcttgattt gctaggtacc
    39541 agctatcagc agggcgagca tcccctaact cgacaagtct ttgcaaagct gtgtttgcat
    39601 caccgaggat cgacaaagat gtttcatggc gtcgtccaaa ttttgacgca tcgatatcga
    39661 tttggataaa ttcagcagtt ggattaaaaa atgcacgtcc aaatgggaag tcgctaccga
    39721 caaataagat cagatcggct tctgccaatg cttcatttcc gggtttagta gcgacacgtc
    39781 cagcaaaacc aagaaagttt tcataatcat caggaataat tccttttgct agaacggaag
    39841 cgacaacagg aactgaaaaa tgttctgaga attctttgat ttgcggaaat ccgtttcgcg
    39901 ttccttgacc aacataaaga actggttttt ttgctttttc aagataaggc aaagcagcta
    39961 gcaaatcttt ttcttctggt aatatcacac ttgttttgtg agtgtgagcg gtggagaaag
    40021 gttgttcgtc aatttcttca aaaccaagat caacagggat agtcacgata gccacgcctt
    40081 tatgctcata ggcggcttta atggcttcat ctactacatg cggaagactt tgtggtgtca
    40141 tgactgtacg attgtatacg ctaacatctg cgaaaatagg attttcattt agttcctgga
    40201 aagagttata gttcatggat gtagaagcaa cttgtcctaa gaacgctact agaggcacat
    40261 ggtccatctg tgcatcatac aaaccattga tcaaatgtgt cgcaccaggt cctgcagagc
    40321 cgaagacagc gccgactttc cccgttaatt ttgcatctgc agcggctgcg agtgcgccga
    40381 cttcttcatg acgaacttga atgtagttga tttcggtttt ttcttgatat agcgcatcca
    40441 taattgaatt gaaagatcct ccgggaatgc cgtaaatatg gtcgataccc cagctttcaa
    40501 gaacttttac cattgcgatt cctgcattga tttttgacat ggtgtttcac tcctttagca
    40561 atgatgatac ataaattttt tgtatctaga gtatagaact ttttatcgaa aatcccaact
    40621 aattcgtctt ttcacaaaaa tgtagtcatg tttttgggaa tatgctagag tagtacatag
    40681 atagattcaa gagaggggaa tggcatggtt gaatggctat tgagacttga accttggcag
    40741 caagcacttg ctgggacagc ttttacttat tttatgacag ctcttggtgc cgggttggtt
    40801 tttttcttta aagaaatcaa aaaagaagtg ctaaacttga tgttaggatt tgcttctggt
    40861 gtcatgattg ctgcaagttt ttggtctttg ttagatccgg ctattacaaa agcagaagaa
    40921 aatggagata ttgcttggct agttgtaagt attgggtttg gtttaggcgg tgtgttttta
    40981 tatatggcag ataaaacact gccccatatg cattttggac cacaacatga agcagaagga
    41041 ttgcctaccc atttaaaacg gacgatcttg cttgtttttt ctattacatt gcataacatt
    41101 cctgaaggtt tagccgtggg ggtagcattc ggtgcagcag caactgcgga taatccgaca
    41161 gccgctatat tagccgctgt ttcggtggcg ctaggtattg gtatccaaaa cttcccagaa
    41221 ggagcagctg tatcaatccc gttgcgacaa gaaggtctga gtcgtaaaaa ggcctttgtt
    41281 tacggacaag cttctggaat cgttgaacca attgctggag tgattggagc gctactagta
    41341 acgaaagtgg agctgctgct tccttatgca cttgcttttg ccgcaggagc aatgatttat
    41401 gtcgtggtgg aagaattgat ccctgaagca cagcagacat tgtccagcaa acgtcatttt
    41461 gcagtttttg gcgtcatgag tggatttatc attatgatga ttttggatgt ggcattagga
    41521 taaataaaaa aaatatatat gatatatcaa atagggccgc gaacttatat cgcgacccta
    41581 tttttttagt aagttatatc ataatgaagt gaatggtatc atacattaat aatagttttt
    41641 tctatgtgta tttcctttga tccagcgaac aagccagatg ataagtgcga ttgggattag
    41701 aactttgacc gcaaaccata aaagcccgct taggacactg acaaaaagac tgatgacgaa
    41761 gctagctgca attagcacta aaagaaccat gaagatattt aagaacatat ttttttgacg
    41821 catacaaaac cctcctcttg ttcattcttt actatagaaa aagtataaca gggattgttt
    41881 aaaaacacct ccaactgaag actgattttt acttcatcta cttaaatgat caaacaattg
    41941 ctttttctct ggtttatcat ctaaaataga gcggaaaagg aggagaatat catgcctaaa
    42001 aatcgtcttg aagcatttac agatgctgta atcgcgatta tcatgactat tttagtttta
    42061 gaacttcatg aacctaacgg agacacgtgg gaggcgctcg ctgcattagg ttaccgattt
    42121 tttatctata ttgtcagttt tatcatttta gcgatttatt ggaacaatca tcatcattta
    42181 tttcaagttg tacataagat aaatggacgg gtcttatggg cgaacagttt ctttgttttt
    42241 gcgctttcgc tttttccgtt tgcaacttca tggatcagtg agtacatcaa tagcctggct
    42301 ccagaaatga cttatggttt tgttaccttg accgctaata ttgcgtatta tatcttggca
    42361 aaagaacttg tcaaagcaaa taaaggccac gagaaagcat tgaaggcgat gttgaataat
    42421 tacaagaaat cgtatctatc gattggtttg aatgtgttag gaattgtctt agggtattta
    42481 gtagcgccag tagccgtgct gatcgcaaac atcgtgattc tagctgcttg gatcatccca
    42541 agtcgtacca tcgaatcaca atatcggtaa aatgatccgt gtttaaaatt taagagaaaa
    42601 atatagaaaa aataaataaa cgatcaaata tccgagtgat actagtattc aaagagggat
    42661 gcagatggat caaaaaagaa ttcatgtagg actgattact agttttgtca cgatgcttat
    42721 ttatttggat caaggtcatt tgacttggac agtagttggt gtcgtaggat ttttgacatt
    42781 attcacagca ataaaaaaat aaacatcttt atgtaatctg atgttctatc tatttaagaa
    42841 aagcatgttt acagcagtat gattctgttg taaacgtgtt tttatttgtg gaaaatttaa
    42901 tttttagaaa agtgtatcga aaaatagata gttagttttt ccacagtgga taacttcgta
    42961 agagataaaa ataaaaaatt agtcaaagaa gggcgtatag atttcttttg ataggagata
    43021 tacaacagaa atgaataaat attaacgtgt tttcaaacag tataaaacgg tgtggttttt
    43081 ggaataaaaa aataacatat ctcattttac gcttttgtta ttttatactt aaaaaataac
    43141 gacacagaaa ataccgtgtc tcagatttct ctactacttc taaaaactac tgtttttttc
    43201 ctttgaaatg ccttcaaaaa gtaggatcag gcagaatata ctggcagaat caaggagaag
    43261 ggagcctaaa taaggagaaa aaccatagaa aatataaagt aattacttat aaaacaagct
    43321 ttttatagaa aaataatata cctgagtagg gtataaatta agacggaatt cctttctaga
    43381 ttgagatatt gactaggaag aatgttaaga ttttaagcct ttaagctaaa aaaaaaccct
    43441 ttttgttaaa taaggggaat atagcctgtc agtttcaaac tgcaagtcgt cctgctgcaa
    43501 taatatagta gattagagat gaaaatagat ttttttaaac caatgactga ataaaaagac
    43561 cgtcatagat acacattgga atgtgtctat tacggtcttt ttttacgaac gattttattg
    43621 aagacggaca gttcgggtca aaaataaaaa agctacgatc agaaataaga ataaaatgta
    43681 tcccaaaata atggctagac ggtctaactt atttgtcgat agatgtttgt ttagaagttg
    43741 ataggcccat aaacctatca gtcctcctgt tgtattagtt atcaaatcag tgatgtccgc
    43801 tacgccaata ccgaatagga attgaatcaa ttctgccaag aagcttacaa ggaaaataat
    43861 ccctaatttt ttagaaaaag aaagtctctt gaaattgaca ttcaaaagca ccccaaaagg
    43921 aaaaaagaca atcaagttat aagtggtctc acgtaatacc gtcgtatttt caaaagaaaa
    43981 agtagaaaaa gggacgagat tgacattgct gtaagaataa gtgagaaatt gtggaagatt
    44041 aaatgatagc ttgaataaaa tcaaccataa tagaaagaat aaataaatcc ctaataaaaa
    44101 ttttgataca taccgcatag acatctcctc catttaaaaa gtataccatc gaaaaccgct
    44161 gaaaaatcat aaaaaagtat gaagtttaag gaccaacgta gttatcgtac gaaaattaga
    44221 agcttttttt tgttgggaat ccggtttctt taacaaagct aagatagcga gttgcttgga
    44281 aaagttgcta tcttttttct gtcaaaacga ctcggaatgt tcgttttttg ttctaatttc
    44341 tccaagttgt ttactttttg atactaagtt tatgaaaaat caagaaatag ttgttatact
    44401 aggtaatgct gacaaacggg attggcattt catcttggtt cagctttttt tccaattact
    44461 aggaaggagg gatagattgt tcaagactta ttttcgtttc aataaaatac aagataatcc
    44521 ttttcgtatc atgaatctga tgctacttat ctttattgta ttatggttag gttacataaa
    44581 tcatgatttt ttgatttcaa gtttttcatc attagggatc tttacttttt tctattatca
    44641 aaacataccg atgaaatatt tgctgaaacg tatgtttctg atcggttgcg gactgttggt
    44701 tgctttcgtt ttggggatct tatcgactta tgttttatgg cttgaaccat ttgccgtagc
    44761 tttggttgct ttttccagca gattcgtgtt gcgattattc catatttcta aaccaggtgg
    44821 cttgtttttt gcgatgcttt ctgccatggg aacgagcatg cagctgccaa tcgctcaatt
    44881 accgatcgtc tcactttatt tttttatggg tgtcgttttt gccctgattg cggcagtgat
    44941 tacaaaatta ctggattcac ggcctgagca gacaattgaa aaagcaactt taaaagaaag
    45001 atttcacgaa gagcctttag tgatcattga ttctgttttc tacagcgctg ccttatttct
    45061 ttccgtttat gtcagtcacg gcttgaatct gcataatcct tattggttga ccttgtcatg
    45121 tgcatcgatt ttgctagcag aaaacttgga tgcgatgaag catcgacaag tccaatatct
    45181 gattggatcg atgggtgggt tatgtgtgtc ggcattcttg tcatttgtgc cgtttacgca
    45241 gttgcagacc atttttctga tcacttttct atatggaatc gcacaatttc tagttgctag
    45301 aaattatgca gttgctaata tttttcttaa tccgatggcg ttgatgctat ctacacttat
    45361 tcgtggagca tacttgattt ctttgatcga atatcgtttt ttagggatcg tcataggaag
    45421 tttcatcggt ttaggtgttg cgtgggtaat gacggttggt ttgcaacatt atttaacggt
    45481 tgttcgtcaa aaattagaat agaaggacaa atatatgtgc caaaagaggt tatgacaaga
    45541 tttttgtcac aacctctaat tcaaggtgtt caaaagccag attctcagca ttaagtcaaa
    45601 ttcacacaaa aatgtggaaa ggaactttca aaaaaatttt atatttattc tatcaaaaaa
    45661 ttttatattt attctatcaa aaaattttgt ttatgatggt aactgaataa actttcctga
    45721 gatggtcaat gctttccttg aaagtcttac agatattctt tcttcataga aagtttaagt
    45781 tttatagtta gtgtacaata aaagtatgtt tataccatat ggtgtccgga taatcagtca
    45841 tttaaacaat gaggttcaaa gatatgaaaa ggggaaattt gatgaagaaa ataagcaatg
    45901 aaatccaaat tctggcagaa actttaactc ttcccaaagt cgttatagag caaatgattg
    45961 tacaagcaaa aaacatcctt gatgaggtgt ttgagcaata tagtcatgaa ctaatggatc
    46021 ctaataaagc aaaggcgact gcaaagaaaa tagacaaagt ctatgaagag gaaccttttg
    46081 cagcattagc tatttatcta tatgcagctt ctcaaagttg gaaaaaaatt tatcaaccat
    46141 tgaagattcc aagaactatc tatttggcaa caatgaatgc ttttactaga tttattcatg
    46201 aacatttcca agtaacagga agctatcgct ttgaccgtgg tttttggatt tggcattaca
    46261 ctagtggctt gatctttcgg attggtgaat tggagtacga aatgacatat tttccgaaag
    46321 ggtacacgga tctaagatta gaaggaaagc agtgcctttc tcttcatatt ccttccgatg
    46381 cagatttatc tcagaataag ataagagata gttacgaaag tgccattcgt ttttttgaac
    46441 tttattttcc tgattaccat taccaagtga tgtacacaga tacttggtta ctatcaccca
    46501 atcttactaa atggttgaaa aaagagtcaa aaatctgtct ttttgcagcc gattatcgat
    46561 tattatcagt tgatgaacag gacgatagtg gagtcccttg gatctttgga cgagtagatg
    46621 cccaaataca tgattatcca gaaagtacga gtttacagcg acaagcaaaa gagcaattgc
    46681 ttgcaggcga gcacattggc tctggcttag gtattcttac ttcataagtt tagtacttcg
    46741 aaatagttta aaagagcgtg agacaaaagt aaagaacact tttgtctcac gctctaaaca
    46801 cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt cacaaaaatt
    46861 tgaaaagcaa ttttcgtgaa tttcttctta tttcttggag ttaaacgctt ctgtcccagc
    46921 ctctttttta gtgttctatc gaacacacag tacgttcaat aggtaaacta gctataacaa
    46981 tagatattaa agttaacgga caagagggcc ttttttaggt agctaaaacg taataatgaa
    47041 aatttatttc cagagatagg agtcaatcag ctagtctgat cgactgtttt aacaagttga
    47101 ctttcatttt aacttttgat accatttaaa acacaaatcg taattgtttc gatttgtgtt
    47161 ttttagcatg actacaatca aagaagaaag tgggtcgtcc atatggaaaa aacagatatc
    47221 tcaagtgcat accgccgctt gaaaagccca aatatcaaaa cacgaaaacg tgcgctgaag
    47281 atcatcaaag atgtgaaacg gaatagtggg aaaaggtaag aagaaggaaa cttaattaaa
    47341 aaaatagccg aaaaacgttt ttcggctatt ttcaataatc ggtttttgtg taaggtttcc
    47401 gaaagaactg ctgttgattt tccattttta acatatgata aattggtaga atctttcttt
    47461 tcaaattgat accattccct aattccagtt atatagttaa ctacagaacc acaaagcacg
    47521 tacgtttata aaagtattat ctgtagttat ttttcaattc cctttcaacc tcttattttg
    47581 accagtagta ttgatcactt taccttttaa cacctttgtt cgtttttgaa acatttttag
    47641 tcaagaatgg aaacgtaact acataatcaa aggttttgcg aaatatttca tgaaatattt
    47701 catgtagaag cgagcaatac ggttgcaaat aaccattatc gtttaataag cagttacgaa
    47761 agctcccaat atctctaacg ttcagctcac tccatttctt ttcttcaaaa aaatcagtga
    47821 ttcgtatctc tttctatttg tcgaaaaagt taactttaaa aagtaacgcc gaaaaaatat
    47881 gcaaaaaaat aaaaaagcag ttactattgc tagaataaca tcaaggaata ataagttttg
    47941 gttttcagat aatagtcgat aagttgtgta ttggaatttt agatacagta ataaagtatt
    48001 tttcatgaaa ttttgtgaga atcactatta caagtatctt taataaaatt aatggttaag
    48061 gaggaactta aagtagaatg taaatgaata gttgtagtca gtcgattgtg atactagact
    48121 caaagttgca ggaataagtt tttcaatttg tgattggaag ataaaaaatg aaaaagaagg
    48181 gctttttttt atactttgtt gattgtagtg tttattttcc ctctgtttag ccaagtaaca
    48241 ttttctatga ctcaaccagt ttcaagtgag gaacatgata acctttttcg tgctacagaa
    48301 gagtttaaga aatatcagga aaatattgtt ccggagactc cattagctag tgagccaatt
    48361 actgatattg atggaaacca aataggatgg tatatacagt acgaagttat ggtggtaaat
    48421 aatgactcaa tagtaaaaaa tacagtaggc ttagagctaa caccgattga aaaggtgagt
    48481 tcattgttaa cgtatattta tactgatgaa agtgacgaga ctgagatcat tttaacggat
    48541 tactcaaaaa ttgctactga taaaaagtat atattgtgga tgtagacact agtgaaatac
    48601 tttatgatat agaaattgat gaaaatttac tagatgtagc acaagaaatc gatcatcaaa
    48661 agcaggaagc tattcgatat gctggtagaa aagggaaaag aaaatattta ttacgtgaat
    48721 gtagcaaaag ttagagaaga tgaaaatgag tggaaagaat tcaagagtcg ctactcaatt
    48781 aactcgactc cgacatttac agtttacaga gaaggatcga tagaaaaaac tgttttttgg
    48841 actaaagaaa gtggaatgtc tttagctgaa gtagaagagt ttttggatta tgttagtatg
    48901 caacagtaag ggagttctta ttatgaaaaa ttttgacaca tattatgtta ttgttttttc
    48961 gatatctttg ctgttaatat tactaacttt aatgcagtat aaagagtatc cagagtattt
    49021 tattttaact tttgtatatt tagtaagtag ctacacactt ctatataaat tcagaagttc
    49081 ttctagagtt tctaaagttt gtttcttaat tagcttattg attctataat atttttgatt
    49141 tatataggaa attaaaaata ttatagaatc aacactcaga gaacgggttg gtttttaata
    49201 gatttaataa gtactgataa tgaaatttct cctggttggg aaaacgaagt tggttaccct
    49261 gtagaagaat tttttcaaga ttactttgcg gagtatgccg ataggataat gagagattac
    49321 gtaacagata aaactcaaga agtcatcaat caatcccagt cattaaatga attatctgat
    49381 aaggcgaaag aagaagcagt tgccattatt tcttcaggga ttagtgacta tattgatatg
    49441 agtggtgaaa tcaattatgg cgataaagac aaaattgtac gcatgataaa agcttttatc
    49501 aaaacttttg atgtgaaggc agatcttaag tttaatgata cttacctagt aggaaaatta
    49561 attaatatcc ttgggacaga gaaagatacg gaaacgttta tttcctcttt gtctatgttg
    49621 tttacagata agcatttttc aactcagctt ggtggagagg aactagtgga aatcttttaa
    49681 ccattacgcc cagcattaat aaaagtatat caaaaaagta ctcctgatga tttttaagat
    49741 tggtttgaga aataatgtga aaacactatt tttaatgtta attatagata gagatgaacg
    49801 cgtcatatgg ttaaaagaat gaaaaagtca aagatacact gctatatttc actaaggata
    49861 tagcagtgta tctttcatgt cgtttcactg gcagtttttt ataaaaggag gtgtgcattt
    49921 cagttgcttt tctttggtag ttagttgaat cgtttaagaa ttaacggatg tggcagacag
    49981 gtgctctgtc caaaaaccag taaaatcttt gatggttcca tctttattta gctgtgcctg
    50041 ttcaaatact gttttgtttt taccgaatgg atcaattgca ataattgttc cgatccccgc
    50101 acgtttggca gcaagtaatc ctgagtaagc atcttcgata acaagacaat cagccggagc
    50161 taagctcagt ttgtctgccg ctttaagaaa aatatccggt tgcggtttcc cagggaaaga
    50221 gccgtcgtca tagacaatct tgtcccagtc aaaccagcgg gctaaatcga aaatatcaaa
    50281 ataaaaagca acattctctt tgacagtagc cgtggcaatc gttaatggaa tctgttggtc
    50341 agtcagctgg tcaagagtcg cttcaagccc ttttgtcaac tgaagctcgt tttcattttg
    50401 caagcaaagc atacgataat agctttcttt ttcttctgac aatacggcga tctcagaggc
    50461 ggtcaaatgc tctgaaatga aatgtttcaa aatctccgta ttcgtccgac catgaatatt
    50521 ttttaaaata tcctcgtctg ataaaccatc ttttgtatga tcatgtatca tatgcagcca
    50581 agcagcttca tgcagatgag agtccaaaaa cattgttccg ttgaaatcaa atataatccc
    50641 tttcatagtt acgctcctat agtggtattt tcggttgaat cagcaatttg cagatcgaca
    50701 tattgtgcat agtgctcttg aacctcccgc gagatctggc gatccgtaat gagcagatcg
    50761 aaatcatgca aattataaaa cacataaaaa tcatctcgat tgaatttttt attatcaacg
    50821 agtagatatt tcttacggga attatttaga gcgatctgct gtgcttctcc ttcttcggta
    50881 ctgtaagtag agatcgcttc gttgtgaacg ccatttgaac tgataaatgc ttttgtaaac
    50941 tttagtcttc ttaaattgtc gttggtgatc ggtccgacaa atgcgccggt atttttccgg
    51001 aaatcaccgc caatcagtag aatttctggt ccatctgctt gagcaagaat atcaaaaact
    51061 ggataattat ttgtaatgat ccgaattttc ttgttcagta aatgcgtcgc caatagttcg
    51121 attgttgtac ctggtcctaa gaaaatcgtt tctccctcgt gaatcaagga ggctgctgtg
    51181 gcagcaattt cttttttttc ttgaatctgc agagtggctt tttcagtgtg agaaagttct
    51241 tgatctaaag tgtaggaaag actttgagcc cctccatgga cacgcagcag cttgcccgat
    51301 ttttctaatt catctaaatc tctgcgaacg gtcatatcag aaacatctaa ttgattgatg
    51361 atttcattaa cggtaaggat tcctttttta ttgaccattt ctacgatagt aagcaatctt
    51421 tcttttttca acattgtctt cacctctaat ttaaggataa tctatcatat aaacggacaa
    51481 cagtcaatct aattcgaaca aaagtaaaca tttagggtgg tttttatgtt tgttacaata
    51541 gattttattg ctgttttctg gtttttatga ttatttgtgt ttgtttttgt tgacaaatgt
    51601 tttggatgcg tttacaatgc aatcagttag aaagagcgaa aactgattat agatttgagg
    51661 agagatgtac atgcttaaat taccagaaga ttttattttt ggcggagcca cagcagccta
    51721 tcaggttgaa ggagccacta aggaaggtgg caaaggcgct gttgcttggg atgacttttt
    51781 agaggaacaa gggcgattca gtcccgatcc ggcaagtgat ttttatcatc aatatgcaaa
    51841 ggacattgaa ttgtgtgaac gttttggtgt aaatggtcta agattatcca ttgcttggag
    51901 ccgcattttt cctgatggag ctgggaaacc aaatccagaa ggaatcgctt tttatcatcg
    51961 tgtgttcgaa gaatgtaaga aaagaaacgt aacgccgttt gtgacgttgc atcattttga
    52021 tacccctaaa cgtttgtttg accatggaga ttttttgaat cgagaaacaa tagaagcatt
    52081 tgtttcctat gccatttttt gttttcatga attcaaagaa gtcaaggtgt ggagtacctt
    52141 taatgaaatc tatccagttg caaccaatca atatttgtta ggtgttttcc caccaggaat
    52201 caaatatgat tttacaaaga tcgtcgcctg tcttcataat atgatggttg ctcatgcccg
    52261 tgtagtgaac tatttcaaag aaaacgaact tccgggtgaa attggtgtag ttcactcatt
    52321 agagacgaaa tatgcggcaa cagacgcgcc ggaagataag catgctgcct ttttagacga
    52381 tgcattgtcg atccgtttct tattagatgc tacctattta ggctattatt caactgaaac
    52441 cttgactgct cttgatgaga tatgtgaagc aaatcaggcc agctatcatt ttcctgaaga
    52501 agatttcgtt gaattgaaaa aagcatccac gcgtaatgac tacttaggga tcaatcacta
    52561 ccaatgccat tttgtcaaag cttacgatgg agaaaatgca atccatcata acggtacggg
    52621 tgaaaaaggg acctctgttt ataaagtgaa gggaatcgga gaacgtattt ataaagaagg
    52681 aattcctcga actgattggg actggctgat ttatccagaa ggtctatatg acttgttgct
    52741 gcgaattaaa agcgattacc cacattacaa caaaatctat atcactgaga acgggatggg
    52801 gtataaagat cagtttgaag atggcattat tatggatcag ccgagaatcg actatttgag
    52861 agtctatttg gaatccttaa gcaaggcgat aacagccggg gtaaatgtga aggggtattt
    52921 tttgtggtcg cttatggatc ttttctcatg gacaaatggg tataacaaaa ggtatggctt
    52981 gttttatgtt gattttgaaa cccagaagcg ttacccaaaa gaatcagctt actggtacaa
    53041 gttggtcagt gaaaccaaaa cgattattta ataagtgata atggaggaag aaaagatgaa
    53101 taaagaggaa ttacaaatgc ttggttttga gatcgttgca tattcaggcg acgctcgcag
    53161 tacattattg aaattattga aagaagtaag acaaggaaac tttgaacatg ttgattcggc
    53221 gttgaaagaa gccgacgaaa atttaaccct tgcacataat tcgcaaacaa aaattttagc
    53281 ggaagaagca tctgggaaag agatggagat gggattcatt tttatccatg ggcaggatca
    53341 tttaatgacc actttattgc tgagagatct gattcaagac tttattgtac tgtacagaca
    53401 gaatcaagga taggagaaga acgctatgga tggaatcatt aaacaaatcg aaaaagggaa
    53461 accatttttt gaaaaaatct cacgtaatag ttatttagga gccgttcgtg acggattttt
    53521 aacagcgatg ccagctattt tattttcaag cattttcatt ttgattgctg cggttcctga
    53581 gatttttggt taccaatggc ctgaatctgt ctccacatgg ctatggaaag tctataatta
    53641 ttcgatgggt gttgtagggt tactcgtttc agcaaccact gctcgctgct tggctgattc
    53701 gatgaatcgt cgcttaccga aaaacaaagt aatcaacacc acctctgtga tgctggcctc
    53761 tgtggtaagt ttcctgttgt taagcgtctc tccgattgaa ggtggatttt caacggaata
    53821 tatggggaca aagggactac tggcttcctt tgtcgctgca tttttaacag ttaatttata
    53881 taagttttgt gtgctgaaag atattaccat taaaatgcct aaagaagttc ctggaacgat
    53941 ttcgcaaacc ttccgagata tttttccttt ctctttttca gtatttgcgg ccgttttaat
    54001 tgatttaggc attcgacaaa tcttccaaat ctcatttgca gaagcaatca ttacggtgct
    54061 gcagccgcta tttacagcag ctgacgggta cttaggaatc gctattatct ggggagcgat
    54121 ggcgctgttt tggtttgtcg gtgttcatgg accgtcgatc gtggagccgg caattgcggc
    54181 aattatctat gccaatgtgg aaaccaatct gcaattgttc aattccggtg aacaagcttc
    54241 taaagtactg acggtgggtt tagggaattt tgtaggaact atgggaggaa ctggggcaac
    54301 attggttgtt ccttttatct tcctactctt tgctaagtct aagcagttga aggcagttgg
    54361 gaaagcttcc tttattccag taagtttcgc tgtcaacgaa ccattgctat ttgcggcacc
    54421 catgattttg aacccttatt tttttattcc atttttgtta acacctgttg taaacgtttg
    54481 cctgttcaag ttttttgtcg atgtattggg catgaacagc tttatgtacg ttttgccttg
    54541 ggcaactcca gcaccgatcg gtttggttct aggaacgggc atgggtatct tagcttttgt
    54601 tctagcagcg gttctaatcg tcgttgactt cctgatctat ctaccatttt gcaaagcata
    54661 cgatgctgtc ttagtagaga aagaagcaca aaaagcagag gtgatcgcaa ccgaggaagg
    54721 tgcttctgcc gatgtacgtg aggaagtacc tgtggcagcg agtcaagtta tcagcgatgc
    54781 aaataaagaa atcaatgtgt tggtactttg tgctggcgca gggacaagtg cgatgttagc
    54841 taatgcttta aaaaaaggtg catctgaatc gaaagcaccg atcagtgcaa tggcgggtgc
    54901 ttatggttct cattacgaaa tgctgcagga ttttgatatg gtggtcttag caccgcaagt
    54961 caattcttac tatgatgata tcaaagaaga caccgatcgc ttaggaatca agctggttgc
    55021 gacaaaagga gcagaatata tcggattaac gagagatcct gaaaaagctg ttcagtttat
    55081 tctgaaccaa tttcaataaa ggaggagcca taatgaaaat gggaatttgg ttgcgtaaag
    55141 ctgttttatt tgcagctgtg ttaggggctt tgggggctgt ttcaaaaact gttgaagcat
    55201 ctgccagcga atttattcgc ggagcagata tttcgatcct gtcagatatg gaaaaatctg
    55261 gtgcaaaata ttatgaagac gatatttcaa aagatgcctt agagatttta aaaaataatg
    55321 gtgtcaacta tgttcgactg cgtttgtggc aggatcctta taatagtaat ggagaaagtt
    55381 atggagcagg gacaaatgat ctggaaacga cgattgacct tgcaaaacga gcaaaaaatc
    55441 tgggacttaa ggtgctgctg gattttcact acagtgattt ttgggttgat cctgggaaac
    55501 agaatcttcc taaagcatgg caaggtctga cctttgaaga aatgaatacg gcattgtacg
    55561 actatacaaa gaacgttctg tcggaaatga agcagctgga cgtttatcct gatatggttc
    55621 agatcggcaa tgaactgaat agcggaatgc tctggcctta tggcaagtct tggggagaag
    55681 gcgggggaga atttgatcga ttggctgctt ttttgaagtc tggtatccaa gctgttcgag
    55741 acactcaacc taaaacaact ccagtaatgc tccacttagc tgatggtggc gatacaggag
    55801 catttacttg gtggtttgat gaaatcacga gtcgaggtgt gtcatttgat ttaattggag
    55861 tgtcgtatta tccgtattgg cacggttcaa tgaatgaact tcaaaccaat atgaatgcga
    55921 tcagccaacg gtatggtaaa gaagtgatcg tagttgaaac agcttatggg catacaacag
    55981 cgaatgccga tactatgcca aatgcttttg gtgaagccga agcagctgcg gggggatatg
    56041 aaccaacacc gacaggacaa gcagagtatt tgctggatct tgccgatcgg attcaggcag
    56101 taccgaataa tcgcggggcg ggcttcttct attgggaacc tctttggtac aacggaaatg
    56161 tgagttgggc aacacaagca ggtatgaatt atctcagtgt tcaatccact atgggaaacg
    56221 aatgggacaa ccaagcgatg tttgattttg ctggaaacgc cttgccaagc ttgcgtgcgt
    56281 ttaaacaagc aggggcgcaa ataaatctag ttaaaaatgc aagtttcgaa agcgatggac
    56341 caacgaccag tccttccaat tggcaaacct ggtttcaaca aggaaccgct aagggtacga
    56401 tcaaaacgga agcgggcact ttttttgggg actacaaact aactttttgg caggatcaag
    56461 catacgaggc atcagcttat caaaatgtta gtggcataag caaaggaact tacacattga
    56521 gtgcctatgt aatgtctggg ggagagtttg atactaatca gttatatatc aaaaattatg
    56581 gtggagcgga actaaatact gcggttgtta aaacaagtga atggacaaaa attacaatca
    56641 aagacattcc aattacaaca ggtgtttgtg aaattggggt ttatagcaag gcttcaggaa
    56701 atgcttggac gaacgttgat tttgtttcat tggtgaaaca atagactgcg gatcgtttcg
    56761 attcaagatc ggaggttccc ttcagccaca tcgttagcgt agaaggcagg aatcgaacct
    56821 gcacctcgcc tttgccaaaa ataaccagaa acgatttcca gtcattttta ccaaaacgag
    56881 taaagcacca gacttcatct acactttgta ttatgctaaa gagagttcaa cgatttcgta
    56941 agaagcaatg aaaaaattgc aaaaagttgt gcagataaca taaagtttgt ttaagaaagg
    57001 gtaaccttag aattccgtcg tgaatatgat ttgagcactt agatggatag aaaaaagttc
    57061 tcggaaaaca gttcgttttt cgagaacttc tttttatgat aagaatgaaa caaattaact
    57121 tatattatag tctcttttgg tagggaacca tcttattttt aatgaaaatc aagcatttta
    57181 gctattgaag aatgttgatt tatagggatt ccccctccat attatgttgg ctctttattc
    57241 ccactctgtt ttcaacgtaa agtgtataaa acagaatgcg atactatcaa gggagttaaa
    57301 acaatataca gaacagtaaa acactataaa taaaaataaa agtgcaataa aagtgcaatt
    57361 tttgcaccta atcatactct gtttatatat gaaaactaga ttctgaatcc aatatttggt
    57421 taacgagagg cgttcgaatt tgaacgtctt ttatatatta ctttcaaata aatatgaggt
    57481 agaatactat ctattttctt tttaacccaa ttgttataat ggagagtgta aaatattttg
    57541 tgtaaataga aaaaaggaag tcccttctgt agaatagagt taccacaaca cattcacaga
    57601 agagaggact tccctatgaa cgattttact acagaaattc taaagactct agcgaacaaa
    57661 ggcgatttga atgaattatt ccgtgtccat ttggagaaag cagtcaatac gcttctcaaa
    57721 acggagttaa cggctttcct agattacgaa aagtatgatc gcattggttt taacacgggt
    57781 aattctcgta acggctccta tgaccgtacg gtcaagaccg agtatgggga acttcatctc
    57841 cagattccgc gcgaccgcaa tggtgagttc aagcaacaga ctgttcctgc ttatagacgg
    57901 acgaatgaca cgttagagga gaccgtcatt cacctcttcc gaaaaggtat taccatgtcg
    57961 gaaatcgcag acttgattga gaaaatgtat gggcattact acacgcccca aaccatgtcc
    58021 aatataacaa aatcatttac agaagaggta acggcgttta atgggcggga gcttcatgac
    58081 cgttatgctg ctatttatat ggacgcaacg tatattccgt taaagcggaa aaccgtcgcc
    58141 aaggaagcta ttcatatcgc agttggcatt cgcccggacg gatcaaagga agtattgagc
    58201 tatgcgattg caccgactga atccatcacg atttgggagg aaattttatt ggaccttcaa
    58261 gagcgcggtt tgaaaaatgt cctcctgttc atcacggatg gcttaaaggg gatggtagga
    58321 gcgattagtc ggttctatcc caaagctcgt tttcaacatt gttgtgtaca cgtttcccgt
    58381 aatatcagtc ataaagtgcg tgtcgatgat cgtaaggaag tctgtgatga ttttaaaatg
    58441 gtgtatcaag cctcatctaa agaggtggcg ttggaagcac gtggtacttt tgcggaaaaa
    58501 tggaaaacca gctatccaaa agtggttgaa tcgattcttt cgaacgatca cttgctcact
    58561 ttctatgatt tccccttggc catacgcaag agtatttatt ctacgaactt gattgaatcc
    58621 tttaataaac aaatcaagaa atacagccac cgcaaggaac agttccaaaa tgaagagtcg
    58681 atggaacgtt tcttagtctc gtcttttgat acttacaacc aaaaattcct aggtcgcagt
    58741 cataaaggtt tccaacaggc cgaaggcgag ctcgaacaaa tgctaagcca actgattgag
    58801 aattagaaac aatctgcagt agggaagaat catttacaca aaattattga cgctccctta
    58861 taatgagaac ttttactaac ataatttatg ataaacttac tatataatca tattaattaa
    58921 atagttagga gatctgctta tgtttatatc tactcttcaa attcgaaatt ttagaaatta
    58981 tgaatccgaa atctttcgat tcgataatga gacaaatact attataggtg agaatgattc
    59041 agggaaaacc aatgctctta ctgcattgag aatcttatta gatgatagtt attactatag
    59101 tagtaaaaca ctaaaagaat cagatttttt tcatggaatt caaaatgggt ggcaagggca
    59161 ttggattatt atctctgcga catttgaagg aatcagcgaa gaagaatttg acaatgagat
    59221 ttgtgcttcc atttctttaa attctgaaag tcaaacaatc ttagaagaat tgatttcaaa
    59281 tgcagataaa ggtgtaggta gtatttctct atttattaga cctaacaaag ctattagaaa
    59341 gcaattattt gatatttcca ctgaattaga ctctcatcaa tttaacgaat ttagaaattc
    59401 tattcgtcta tccgactatg aattttacta cacatctaaa tcaaatctaa atttctgtat
    59461 caatgaaaat tatgataaat tggtaggaag actcaatgac aatatagcta gtaatcctga
    59521 agaagacgat gaagctctgt tgggctcaag aattgacatg tcagatattt tcaagcatat
    59581 ttcggttgtt tatgttgacg ctcttcgaga tgttcttaga gaaatgaaaa acaatcgaaa
    59641 cccagtcaaa agaatcatgg aaacaattga atcaaaaata tcatcagata atgttgagtc
    59701 attaaaaaca attatacagc aattaaatga gactattacc agtgttcctg aaattaggaa
    59761 aattggcgaa aatattaatc ggcaactaaa tagcataatt ggttcagtgt attctcctaa
    59821 tcttcttctt tcctcaacta tgtcagatga tatgggttct ttagcaaaat ttctttcaat
    59881 gaagccagaa caaaatatcg acttagactt actagggtta ggacatctaa atatgattta
    59941 tttagctttg aaaatagtcg aatttgaagc gtgtcgttca agagaactac ttaatattat
    60001 gttgattgaa gaaccagaag ctcatattca tcatcatatt caaaaaactc tgttcgaagg
    60061 attaaatctt caaaaaaact atactcagat tctcatgacc acacattctg tacatttagc
    60121 tgaagtgtct gaaatatctc ggatgaatgt attaaaatcg tttaatggca aatctatcgt
    60181 tatgaatcca gcaaataatc tgaactcatt tgctaaagaa aagttaaaaa agaacaatct
    60241 aaatctaata aacgcagtag agagatattt agatgttaaa agaaatggat tgcttttttc
    60301 taaaggtgtt atcttagttg aaggagatgc tgaagaaata cttattcctc aaatagtaaa
    60361 aaaattattt ggtataaact tagacgaact tggaataggt ttgattaatg ttggtagtac
    60421 ttcgtttgaa tatatcgcta gcttgtttga cgatgataga atacagagaa agtgtgctat
    60481 tgtaactgat ttagatgaac aggcaatccc atcagaacat cgattgtata aaagcactgc
    60541 acaagagaaa ggtcaagcaa gaaaagaaaa attatcctcc ctttttaatg aaaacaattg
    60601 ggttaattgt ttttatgcta atacaacatt tgaaattgag tttttagatg tgaataaaga
    60661 aaatattcta acttatgtca gtccaattat agatgacgca ttcaaagata aaaaaacaat
    60721 aactgcttat aaagaagaaa tacaaagtga acaatattta gaaagaaatt tagcgatgtt
    60781 aaaactagcc aatcatgttg gtaaggggtg gtttgcaatt gagttaggtg aaaaaattga
    60841 ctttttaatc aaaattccta agtatattct taatgctatt gcttttgcat gtcaggaaat
    60901 agtagatctc tcaatttata aaaaaattct actccataca atcgacttgt acgaggaaac
    60961 tacagaattg tcagctttat cagctagttt aaaaacaagt gatacagctg atttgaatat
    61021 agcaataatt tctttattag agtactttgg taaagatgag gatgttgtgt atctaatcaa
    61081 tcagatagaa aattacacaa aaatacttta tgctgaggtt tcaaaatgac aaatatcttc
    61141 gaaaaaatcg taaatgattt aaatttagaa caaaaagatg ttgtggaaag tgaagataac
    61201 ctttatgtaa atgcatgtcc tgggagtggg aaaacaaggg tacttacaag gaaaattgct
    61261 taccaagcaa ttaaacacga tggatcacta aaaagaataa ttgctatcac atacactaat
    61321 agagctgctg aagaaattaa ggaacgccta agtttactta gtatagatga tgatattaat
    61381 atttgggtgg ggacaataca tcagttttgt cttgaattta ttatttatcc ttttaaaatg
    61441 aatctctcaa gagtatcaaa aggatttaca attattgatg attatactca aagagcttac
    61501 gtcagccaaa ttaataatat gctgaattta aatctcaaaa cgtatgaact gaacaaaatt
    61561 gatttgtcac tttctcatga ttttaaaatt aatgaagttc agtatactca agtttctgaa
    61621 atgtatcaca ctatgttgga aaaaaataaa gaaattgatt ttgatatgat tttactagta
    61681 gcgtataaaa ttttaactgt aaacagtaac gttgcacgta atattgctag taatataagg
    61741 gcgatttatg tggatgaatt tcaagatact agagaattac aatacaatgt aatagctaaa
    61801 ttacttcaaa acaaccctca aattcagtca atgtttgttg gagatattga ccaagcaatt
    61861 tatggatcat tagatggtat agctaaatca gttgaagaac tagaaatgct aactagtcac
    61921 acttttcaat caaagacgct acatggctgt tacaggtcta atcagagatt agtagacttc
    61981 tactctaatt ttcagagttg tccttacgag attgaaagca gagggaataa taaaaacgac
    62041 cgtggtttta taagttatga ttgcaaagtt actaaggagg atttacccaa cataataaaa
    62101 aatataataa aggaaaagat tgaaagcggc attcatgaaa aagatatttg tgtacttgct
    62161 cctcaacact atcctctgtt ttcactgggt gagtatttaa agaaagaatt accgtattgc
    62221 aattttgatg ctataaatat atcaccaatt aaggtaaata atcatagttt atttttcaag
    62281 ttagcaattt tgtactttac tgaatcaggt gaaaaggttc gaagaagaaa gctaattgca
    62341 aacgatattt taattatatt aaaaaatgaa tttggaatag aagttaaaga ttattttatt
    62401 gacttagatt tattacagct aataaacagt gtgaaaagaa tgtatagtgg agacgacaac
    62461 ggtgttgatt tatacaaatt tgttaccaaa catatatttg ttaatcttaa tattgacgag
    62521 aaaaattacc cgtctatttt taagcactat ctatttttta ttaacgaagt agaagatcgg
    62581 ataaaaaata attcattatc tagtagtgta tctagtttta agaagatgtt taaatctcga
    62641 gatggtatca cacttactac agcacataaa gttaaaggaa atgagtatga tactgttatc
    62701 gctattaatc ttctaaacgg gaaaattcct cattggaatg aaatttttaa tgtttctgat
    62761 aaaggaatta gttcagcgag aaaactacta tacgtaattt gttcaagagc aaaaaataat
    62821 ttatttcttt tctcagaggt gggttatttt acgagtaaag gagacttgct ttatcccact
    62881 caattattag ataaaataga atttgattat aatatttaaa atacctaggt agtcgttgtt
    62941 ttaaatatag taggaatcgg acgctcagta cggagcgtct atttttttac ccaattttga
    63001 aaggaagtga acttatgaaa ataaaaaatc aagaatcaaa aggtcgctct ccccccttta
    63061 aaaccatcac acaaataaga ttcattcaaa cataaaaaca gaaaggatag gtaaaaatat
    63121 ggaacttaaa tatgtcattc ccaatatgga aaaaacattt ggacaattag aatatgctgg
    63181 tgaagggaac attgaacaac gtcgaataaa tggcagacca accattctct ctcgtagtta
    63241 caatttatac tcaacgattc aacgagcaga tgatattgtt gtcattcttc cctccgaagc
    63301 tggcgagaaa cattttgaat ccgacgaaaa agtcaaactc atcaacccac atattaccgc
    63361 agaaggttat aaaattggca atcgaggatt taccaattac attatgcacg cagacgatat
    63421 ggtgaaagca taagaaagga aaggtgaaaa aatatgagat tagcagaagg tattgtgatt
    63481 gaaaaagacc agacatttgg cacattgaaa ttttccgcct tgcgtcgtga ggttcgtatc
    63541 cagaatgaag atggtacggt ttccgaagaa attaaagaac gtacctatga cttaaaatca
    63601 aaaggacaag gacgcatgat acaagtcagt atccccgctt ctgttccttt gaaagaattt
    63661 gactacaacg cagaagtgga attaatcaat cctgtggcag ataccgtagc gacggctact
    63721 tttcgagggg cagacgttga ttggtacgtg aaagcagacg atcttgtatt aaaaggacag
    63781 acaaaacctc atcagaaata taaaaaagaa gcgtccgaaa gtgaaaaata ggtgttgctt
    63841 atgacaaaca caccattgat tttgaaagaa attccgaagg atgaagccat ttcttttatt
    63901 cggcaatacc attattcaaa gatactccct agattgtgta aatactttct agggattttt
    63961 tcagaagaaa aattattagg cgttgtggaa ttaggctggg gtacgcaacc cctacaaacc
    64021 atacgcaaac tctttcccga cagttccctt caaaccacag attatttaga aattggaaag
    64081 atgtgttttc ttccagaaat gaatcaaacc aattattttg gcagtcaagc tctttcagct
    64141 ctaattaagt ggttgaaaga acatacggac tgtcattttt tatatacact ggcagatgga
    64201 attgagggaa aatgtggcta tgtctatcaa gcgtccaact tcttttactg cgggtatttc
    64261 aagacaagtg tctatcgtga taagcagtca tgggaaaaga tacaccctcg aagtgctcgc
    64321 cttttattag aggaaaatgc tcgctttgaa caggtagaga aaaagcattg gctttcccag
    64381 gcattttgcg aatacaaagg gattgagaaa atcaatggac gcatgtttcg ctatctctat
    64441 ccgttgacaa aagaagcgaa aaaactgtta ggacacactc tctatcgacg tcattattat
    64501 ccgaaagaaa aaaatttacg ctttgaaaag cgaatcgctt atcagaaata tgaagccatt
    64561 tctcaaccaa cttttgataa acaggctcgt atctacaata cacaattatt ttgataggtg
    64621 gaaaggagga tttttatgcc attgcttcat gacagaggag agcgaatcaa agccaacgat
    64681 aagcacttgg tctatcattt tgtactaatt tcattgctgg tagtttttct agtcgtccta
    64741 ctcccttttc attggagagc gttacaatcg gtgaactggc aagcagttca gttagataca
    64801 tttttctatc aacttcatac gccatacttt tggagcagta ttctcactgc tctttttgta
    64861 tgcggactta tcagctggct ttattatcac tatcgtatag attctataaa acagttagag
    64921 caccgtcaaa agttagctcg tatgatttta gaaaatcatt ggtatgaagc cgaagaaact
    64981 caatcagagg gattctttaa agatttaccc agcaagaaaa ccaaacaacg aatccgccat
    65041 tttcctaaaa tatattatcg aatgaaagat ggactaatcc atattcatgt agaaatcacc
    65101 ttagggaaat atcaagatca gcttttgcac ctagaaaaca aactagaaac aggattgtat
    65161 tgtgaattag tggaaaaaac gttgaaagat tcttatgtag agtatgtcct actttatgat
    65221 actattggca atcgaattgg cattgaagac gtggtagctc aagatggacg tgtcaaattg
    65281 atggaatcgg tctattggga gttcgattct ctccctcaca tgttaattgc tgggggcact
    65341 ggtagtggaa aatcctattt tattctcaca ttgattgaat ctctcctgca tacaaatgca
    65401 aagctttata ttcttgaccc taaaaatgct gatttggcag acttaggggc ggtcatgaat
    65461 aatgtctatt accgtaaaga agatatgttg gcatgtatca atcaatttta cgaagatatg
    65521 attgatcgca gtgaaaccat gaaacaacac cctaactata aaacaggaga aaattatgct
    65581 tatcttggtt tgtctgccaa ttttcttatt tttgatgaat atgtggcaat gatggatatg
    65641 ctaggtcgtg aaagtaccac cgttattcat aaactcaaac aaattgtaat gttaggacga
    65701 caagcaggct tctttttaat tcttgcctgt caacgtccag acgcaaaata ttttagtgat
    65761 gggattcggg acaactttaa cttccgtgtg gctttgggtc gtatgtctga aatgggcttt
    65821 ggtatgatgt tcggaagcga tacacaaaaa caatttttct taaaacccat caagggaaga
    65881 ggttacgtgg atacaggaaa aagtgtgatt agtgagtttt atacacccct tgtaccaaaa
    65941 aggtacgatt tcttaggaga aataggaaaa gtcattcaaa aaaagcaatc tgagcctgta
    66001 ccgcacgaag tgaaaggtac aggttcagac ttgctttgat tggtgtggcg ttagccacgc
    66061 caatccttta gccccctcta tctaacaggg gggcacaaat acaactgaaa acaggcaatt
    66121 ctcatcaacc aatgttgatg gtacaaagga ttgcggaaaa tatgaaaggt gtaaactcaa
    66181 gggtcatagt ttacatcttt tttagattgg aggtttgcga atggaaaacg aaaaaatttg
    66241 gattaaggaa ttgaaagaaa agcgactggc ttatggcgtt tctcaaaata aactggcggt
    66301 tgcttctcat attaccagac cttacctatc ggatattgaa acaggcaagg cagtccctac
    66361 tcaacaggtg aaagaagatt tactgaacgc tttggaacgc ttcaatcccg ataacccatt
    66421 ggagatgtta ttcgactatg tacggattcg attccctacc aatgatgtgg ctcaaattat
    66481 cggtgaggtt ttacgtttga atatggatta tatgctacac gaagactttg gctattattc
    66541 ttatcccgaa cactatcgtt tcggtgatat tgttgtccta gtctctcatg atgtaagtaa
    66601 aggtgtttta ttagaactga aaggaaaagg ctgtcggcaa tttgaaaact ttctattggc
    66661 tcaacatcgg agctggtatg atttctttca agattgcatg gaacataaag gtattttcaa
    66721 acgcttggat ttagctatca acgataaaac agggattttg aatattccag atttggcaaa
    66781 gaaatgtaaa caggaagaat gcatttccgt ctttcgaagc tttaaaaatt atcgcagtgg
    66841 tgaattggtt caccgtgatg aaaaaccata catgggaaac acactttata ttggctcatt
    66901 aaaaagtgaa gtctatttct gtatatatga gaaagattat gagcaatacg tgaaaaatga
    66961 tgttccctta gaagacgcag aagtaaagaa tcggtttgaa attcggttaa aaaatgaccg
    67021 agccacccaa gccatgaaag atttattggc acatcaacag gcggaaaaaa cagcctttga
    67081 aattatcaat cgctatatcc gctttgcaga taaagacgac actaaacgtc ggagtgattg
    67141 gaaaactaat gaacgttggg aatggtttat cggtaaaaat cgtggagcat tacgcctaac
    67201 cacacagcca gagccttatt cttttgaacg aacattgaac tggttacatc atcaagtcgc
    67261 ccctacatta aaaatcgcaa gcattttaga tgttctcaac ggtacaacca ttatctccac
    67321 catgattcag gaagccaaac tgacagaaaa acatgagaaa ttaattgaac aacaacatct
    67381 agccatggag gatttgatta catgagcctt ttaacaaaag aattaaagaa gttagggttt
    67441 cagtgtggca ttgagtttca agcgtatata caaaatacag ggaaatatac gtctctcatt
    67501 attgagggaa aacggcaagc tggtgatacc atctatacct atgattttta caaggtgaga
    67561 ttttataata attataccaa tcgagtaacc gtctatggag agcatttaac cccttttcaa
    67621 ttattaaggc gtgtaaaaag ctatatctat tatcgagaaa aatatcttaa ggaaaggagg
    67681 acaatcacat gaattttggg cagaatttgt acaactggtt cttggataat gcacagtcat
    67741 tggtattgtt agcgattgtt gtcattggac tgtttttagg ttttaaacga gaattttcaa
    67801 aactcattgg cttcttgatt attgctctaa tcgccgtcgg acttgtgttc aatgcagctg
    67861 gcgtgaaaga tgtgttatta aacttattta accgaatcat tggtgcttaa cagatatttt
    67921 tcatgataaa ataggaagta tatattttgt tatgaaagga tttatgaata tgtttacaaa
    67981 tgatcaattt aaatctcttt taattaaaac attagaaaga aagagctctt caaattatta
    68041 tgaaggaggt aacgagattg tttctaaaat gaaaatatca gaggtaactt tagatgagac
    68101 tgacgatttt acttattata aaggatataa aaagggctgg aatacgcttt gcacatatct
    68161 taaaataaga gttccttttg atgatttaga cttttttgaa agtcataaag atttgattac
    68221 ccagacagca agctccatat atgataaaca aggtgataat gtattagtgg atactatttt
    68281 agtaccactt ccagagaatt acgaagtaat taactttagt cagttgaaaa ttagtgatgt
    68341 ggtttcacaa gctattgaag acgctgagtc ttttatgagt aatggtgaat atcaacgtgc
    68401 ctttgacaga gttcacactg cttttcatgg atatttaatt gaaatactaa aaaaatatga
    68461 aattacagtt cctagagacg aaaatctatc taaattatat agtaggatac aacaattaat
    68521 tgaaaaagaa attcaaccta ctgaacttgc tgatatagtg aagacaacga taaggtcatc
    68581 aaatggaatg attagctctc ttaatgaagc aagaaatagg cattcacttg cacaccctaa
    68641 tacaaatatt attggaaaga gagaagcaaa actaataata ggtatttcaa gtacagttac
    68701 agattatatt agcggatacc ttgataagta gcgtcattaa ctgattgcta ctttttttat
    68761 gactattttt ataaaaagga tgtgataaga attggaaatg aaagtctatg tggcaaattt
    68821 aggacggtat aatgaaggtg aattagtcgg agcatggttt actccaccaa ttgatgagga
    68881 agaaatggca gaaagaatcg gtttaaatga ggactacgaa gaatatgcaa tacatgattt
    68941 tgagcttcct tttgatgtgg acgaatacac gccgattagt gaaatcaacc gtctatgtga
    69001 agccattcaa gaaatcgaag gtacacctat ttataatgaa ctcaaagaaa ttcaaggcat
    69061 gtggtttagt agcttggaag aattactgga aaacaaagag gatattcatt gttatagtga
    69121 ttgtgattcg atggaagatg tcgcccgtta ttacgtggaa gaaacaggac agcttggtga
    69181 agtcccttcc aatttacaaa attatattga ctaccaatct ttgggacgtg atatggaaat
    69241 agagggtaat tacctagtta cctctcatgg ggtatttgaa tattgtcagt aagtttaaca
    69301 atccgtgtta taattaaatt aataaatagc acggagaggt ataaattatg gtaaatgtat
    69361 ttgaaaatct taaactatta aaactagaca tgaaagataa aggctgggtg atagattcct
    69421 tttactttcg ttacaaacag caaaattata ttgtacttgt taagctattt gaaaaagagg
    69481 aaaaagttcc agaatatgct ctgttaaaac tagaattttt aaaggaaaac gatttttcag
    69541 atatgctagc tgtctatgct aattcggtaa aattatatac agacacgaaa acaataagag
    69601 aatattttgg tatcgaatac agtagtaact tgggagatgt tttatttcaa tttagccaaa
    69661 ctcttgctcg atttattccg acagaagtta gtgagaagaa aaatgaagac caaaaagaag
    69721 ccatgtgttt ctcattaagt caaagtgatt cagaagatcc cagaaaaaaa tattgttttt
    69781 cagttagaag aaatccttta aagggaaatg gtgagctggg aaaacgaagt ccttttaatg
    69841 acaataaaac gagattgtat agacccagct tatatgaacg attagggtca gataccaatt
    69901 taagtttcag atattcaatg aatccagatg atgaagaaac tgatgaaggt attattgcaa
    69961 aatggacaaa aaataaaatt gaatagttaa agcattgaaa gagcaatcac ctattttgat
    70021 tgttcttttt ctatttttac ggaaaggacg tgaagacatg aaaaaaataa gaagttacac
    70081 cagtatttgg tcagtagaaa aagtgattta tgcgattaat gatttacaac tccctttccc
    70141 aattaccttt acgcaaatga catggtttat cgtttctttg tttgtcgtca tactctttgg
    70201 cagtttacca ccactttctc tgattgacgg agcactactc aaatacttag ggattcccat
    70261 tgttctcact gggttcatgt gccaaaagac ctttgacgga aagaaaccct atggatttct
    70321 aaagtctatc attacctatg ctctacgccc taaagtaacc tacgctggca aacaaatacg
    70381 attaaaaaaa gaaacaatga atgaatcgat tacgattgta aggagtgaac aactagatgg
    70441 catatccgat taaatatatg gaagataatc tcgtatttaa tcatgatggc gaagtattcg
    70501 cttattatga attaattccc tataattaca gttttttaag ttccgatgaa aaaattcaag
    70561 ttcatgataa tttctgtcaa ttgattgccc aaaatcgtga tggcaagatt catgctctgc
    70621 aactagcaac cgaatcaagt attcgagcca cacaggaaca atcgaaaaaa gaaatcactg
    70681 gacgattaaa agagatagct tacgaaaaaa tagatgaaca gaccgaagcg ttaatttcta
    70741 tgattggtga caatcaagta gactatcgct tttttattgg ttttaaactc tacctcaatg
    70801 aacaggaagt atccgtaaaa aatgttggga aagaaattca aaaagcattt gcggaattct
    70861 ttcatggtgt gaatcacaaa ttaatgggcg attttgtttc tatgcctatg gcggaaatcg
    70921 aacgcttttc taagatggaa cagttgttag aaagtaaatt atccagacgc tttcagattc
    70981 gtaaattgga gaaagatgat tttggttata ttattgaaca tctttacggg caaacaggtg
    71041 tcccttttga tgactacgac taccatttac cgaaacgata cgaagataaa aaagtgttgg
    71101 taaagaaata cgatattctc aaacccactc gctgtttaat cgaagaaaat caacgctatt
    71161 tacggattga acaggaagat accactactt atgtggcgta ttttacaatt aatagtattg
    71221 ttggtgaatt ggatttccct aatagtgaaa ttttttatta ccagcaacag cagtttactt
    71281 tccccgttga taccagtatg aatgttgaaa ttgtcgccaa taaaaaagcc ttatctaccg
    71341 ttcgcaataa aaagaaagaa ctgaaagatt tagatagcca cgcatgggaa agcgacaacg
    71401 aaaccagtac taatgtggtg gacgctttag aatctgtcga tgaattagaa agtaatttag
    71461 accaaaccaa agaatctatg tacaaactaa gctatgtggt acgggtatca gcaaagaatt
    71521 tggacgagct gaaacaacgt tgtgatgaag taaaagattt ttatgatgat ctgtctatca
    71581 aattagtacg accttttggc gatatgctag gcttgcataa tgaatttatt ccctcaagca
    71641 agcgatatat caatgactat attcaatatg tcacgtcgga ttttttggct ggtcttggtt
    71701 tcggtgctac acaaatgatt ggtgaaaatt ctggtattta cgtcggttac aatctcgata
    71761 caggcagaaa tatttatctc caacctagcc ttgcaagtca aggaattaaa ggctctgtaa
    71821 caaatgcatt agcgtccgct tttattggtt cattaggtgg cggaaaatca ttctctaaca
    71881 atatgctggt ctattattca gtactctttg gcggacaggc aaccattgtt gacccaaaag
    71941 ctgaacgtgg tgaatggaaa gaaaccttac ctgatattgc ccatgaaatc aatattgtta
    72001 atctcacgag tgagaacgac aataaagggt tacttgaccc ttatgtgatt ttaaaactcc
    72061 cgaaagattc agaaagcctt gccattgata ttctcacgtt cttaacaggt atttccagcc
    72121 gagatagcga gaagtttcct gtcctgcgta aagctattcg gagtgtaact caaagcaaac
    72181 aacgagggtt gttattggtg attgatgaat tgcgaaaaga agatacgccc atcagcaata
    72241 gtattgctga ccatatcgaa agctttgtcg attatgattt tgcccatctg ttattcagtg
    72301 atggcagtgt cacccaatcc attagcttgg aaaaacaact caatattatt caagtggcag
    72361 atttggtctt acccgattcc aatagctctt ttgaagaata cactaccatg gaattattaa
    72421 gtgtggcaat gctgattgtc attagtacct ttgctttaga ctttatccac tctgaccgtt
    72481 ccatttttaa aattgttgac cttgatgagg cttggagttt tttacaagtg gcacaaggaa
    72541 aagctctatc tatgcgattg gttcgagcag gacgtgccat gaatgcaggg gtctatttcg
    72601 ttactcaaaa cgcggacgat ttactagatg aaaagatgaa gaataatatt ggcttgaaat
    72661 ttgcctttcg ttccactgac ctagtggaaa tcaaaaagac cttagaattt tttggtgtgg
    72721 acaaggaaga tgaaaacaat cagaaacgct tacgtgaatt agaaaatgga caatgtttag
    72781 tttcagacat ctatggtcgt gtaggggtta tgcagtttca cccgattttt gaagagttgc
    72841 ttcatgcctt tgataccaga ccgcctgtgc gaaatgaggt ggaagaatga cacaaaaaca
    72901 aaagaaattt cttcactata gttggataac gctcctttgt gtgggcgtta ttttactttt
    72961 attaggcacg ctgggcaatg cagtacaagc gacaggctta gttgatgaaa ccattgatac
    73021 aagcaatgaa tactccaagt atggtttgaa tcaatatcag cttgattatt atgtggacaa
    73081 tagctggggc tggcttccat ggaattggag tgatggcata ggacaatcgg tgatgtatgg
    73141 attgtatgcc attactaatt ttatttggac aatttctctt tatctatcga acgccacagg
    73201 ttatttggtg aaagaagcct atgccttaga tttcattagt caaacatccc aagcaattgg
    73261 cgaaaacatg cagacgattg caggcattac accgaatggc ttttccagtt cagggtttta
    73321 tgtcggtttc ctccttcttt ttattctcat tgttggaatc tatgttgcct atacaggatt
    73381 ggttaagcga gaaacgacga aagtgatacg agctgtttta aactttgtcg tggtgtttat
    73441 tctatcggct tcctttattg cgtatgcacc cgattatatt gcgaaaatca atgatttttc
    73501 caaagatgtc agtaccgcca gtctgaatat tgggacaaaa attgttcttc ctaacacgga
    73561 tagtcaaggg aaagacagtg tggacatgat acgtgacagc ttattctctg ttcaagtaaa
    73621 gcaaccatgg ctattgcttc aatatggctc cactgatgta gaagcgttag gggaagaacg
    73681 tgtggaaagt ttattgtcta ccagtccaga tacaaacaat ggtgaagata gagaaaatgt
    73741 agtgattgaa gaaattgaag atcatgacaa tacctattta accctaccga agacgatttc
    73801 cagattagga acagtcttct ttttgtttgt attcaatatt ggtatctcga tttttgtttt
    73861 ccttctaaca ggaatcatga ttttttcgca agtgctattt attattttcg ctatgttttt
    73921 gccaatcagt ttcctattaa gtatgttgcc gagttttgat ggcatgggca ggcatgccat
    73981 taccaagtta tttaatgtga ttatgacaag ggctggtatt accttgatta ttaccgttgc
    74041 ctttagtatt tccactatgc tttattcgct gtcagcaagt tctccctttt tcatgattat
    74101 gtttttacaa attgtgacct ttgcagggat ttattttaaa ctgggcgatt taatgagcct
    74161 attcacttta caaagcaacg actctcaaaa catgggcaga caagtgtttc gcagacctcg
    74221 tcaaatgatg aatcgacaaa ccagaagatt tcaacgcagt atgagtaaga tttttcgtgg
    74281 aaaagcaggg tcaacgaagc aaaagacaat gacaacaaag cagaatcaaa ccaataaagc
    74341 taaccatact cgtcaaaatg aacggactac accaaagaaa gaaacagcac tttccaatgt
    74401 gaaaaagcaa caaggcggta tcgggcaacg attaggtgaa aagacagccc atgtattgga
    74461 cacgaaaaat cgtctagtca ataaaagaaa gcaggcaaaa caacagatac aggcgacacc
    74521 aacccatgtc aaatatgccc ttcatcaagg aaaagagaat gtcactcata atgtaacaga
    74581 ctttaaacaa tctatggcag ataccaaagc tcaacgcaaa caacagcgta tgaaccagca
    74641 ggagcaaaaa cgaaagaaca ttgctcaaaa gcgtttggag ctggataaag caaaagaaaa
    74701 aagacgaaaa gaaaacccat catctcctgt tcagaataac cagcagcatg ttcgcaagcg
    74761 tcagcaaacc gtcacgcctg ttttgtcaca aaacactaaa cgtgaaaatc atcagcgacc
    74821 attgaaaaaa gagcaaaaac aaaagacacc accgaagcaa ttcaatcaga ggaagctaaa
    74881 taaaagaacg gataagcgag gacaacaaac atgaagctaa aaataacagt gatttgtagt
    74941 gtggtcttct ctctcttctt ttttctctta ttattcctag tcattttctt tgcagatgat
    75001 acggacagtg gcgaaaacaa caaggattct tctattccac aaggcggtgt gaccgtttca
    75061 ccagaagtgt tggcacaccg tccgttgatt gaaaaatatg gtaaggaata tgggattgaa
    75121 gactatgttt cttatatctt agccattatg caagtggaat cgggcggtac agcagaagat
    75181 gttatgcaaa gttccgaatc tttgggttta ccgcccaaca gtttgagtac cgaagagtcc
    75241 atcaaacaag gggttaaata tttcagtgaa ttattaacca gtgcagaaca acaaggagtg
    75301 gatatagatt ctgttatcca atcttataat tatggcggtg gctttttaaa ttatgtgagg
    75361 agtcatggga aaaaatatac ctatgaatta gccgaacagt tttctaaaga gaagtcgggt
    75421 ggtcaaaaag cagactatcc caatcctata gccatacctg tgaatggtgg ttggcgatat
    75481 aactatggaa atcagtttta tgttcagttg gtttcacaat acctaaccga cacttcccca
    75541 acagaatttg atggtgaaac cgtgcaagtc attatggacg aagccttgaa atacgaaggg
    75601 tttccctatg tctttggagg ggcgtcgcct accacctctt ttgattgtag tggcttaata
    75661 caatgggtgt atgacaaagc tggcatttct ctccctcgtg tcgcccaaga tcagtatgac
    75721 gctacgcaag aaatctctat ggaagaagcc caagcaggcg accttatctt ctttcattca
    75781 acctataatg caggcacata tgtgactcat gtggcgatat atttagaggg aaatcgcttt
    75841 tatcatgcag gcgacccaat cggttatggc gacttaagca gtcgttattg gcaagaccat
    75901 ctgattgggg ctagacgtgt tattcataac taagaaagga atgaatcaaa tgattataaa
    75961 aatcgagcga aaagaaaaga aggagaaacc aaagaaatct aaaaaaccga gcaagcaaag
    76021 aaaagttccg atgattaaag ttggcacgca taagaaatta acctttgttt tatgggtttt
    76081 attgattggt agtgtcggat ttggaatcta taaaaatttt actgccattg acactcatac
    76141 tgtccgtgaa acagaaatca ttaaacagca gattgtcgat accaaccaag tagaaagttt
    76201 tgtgaaatcc tttgcgaaag actacttttc gtggcaacaa tcccaagaag ccattgataa
    76261 acgaaatgaa aaattgaccc attatttgac ggaagaattg caggtattaa atgaagaaat
    76321 gattcgtaag gatattccta ctagttctag tgtgaacgat atacaggtgt ggcaggtttc
    76381 tcaagtgaat gagaacacct ttgaggtact gttttctgtt gaacaagtta ttaccgaaga
    76441 caaagacaag gaaactatat cgtctagctt tcatgtggtt gtccatatag atgaatcaga
    76501 taatatggtt attatcaaaa atccgacaat gagtaagaaa cctcaaaaat cggactacca
    76561 acccaaacag ctagaaagtg accatacagt agatacagaa acgatggacg aaatcactag
    76621 ctttttagaa acgttcttcc agctctatcc taccgccaca gaaaaagaat tgacttacta
    76681 tgtaagtaat catgtgttac ctatgattaa caaggaatat gttttcgagg aattggtgaa
    76741 tcctatcttt accagaaaag ataaccaagt aatcgtgaat gtcgctgtga aatatttaga
    76801 tcaagaaaca aaggcaaccc aaatctcgca atttgagttg atattagaaa aacaagataa
    76861 ttggaagatt gtaaaataac aaatattggt acatgattac agatactttg taatcatgta
    76921 ctctttttga taaaaaattg gagattcctt tacaaatatg ctcttacgtg ctattattta
    76981 agtgactatt taaaaggagt taataaatat gcggcaaggt attcttaaat aaactgtcaa
    77041 tttgatagcg ggaacaaata attagatgtc cttttttagg agggcttagt tttttgtacc
    77101 cagtttaaga atacctttat catgtgattc taaagtatcc agagaatatc tgtatgcttt
    77161 gtatacctat ggttatgcat aaaaatccca gtgataaaag tatttatcac tgggattttt
    77221 atgccctttt gggtttttga atggaggaaa atcacatgaa aattattaat attggagttt
    77281 tagctcatgt tgatgcagga aaaactacct taacagaaag cttattatat aacagtggag
    77341 cgattacaga attaggaagc gtggacaaag gtacaacgag gacggataat acgcttttag
    77401 aacgtcagag aggaattaca attcagacag gaataacctc ttttcagtgg gaaaatacga
    77461 aggtgaacat catagacacg ccaggacata tggatttctt agcagaagta tatcgttcat
    77521 tatcagtttt agatggggca attctactga tttctgcaaa agatggcgta caagcacaaa
    77581 ctcgtatatt atttcatgca cttaggaaaa tggggattcc cacaatcttt tttatcaata
    77641 agattgacca aaatggaatt gatttatcaa cggtttatca ggatattaaa gagaaacttt
    77701 ctgccgaaat tgtaatcaaa cagaaggtag aactgtatcc taatatgtgt gtgacgaact
    77761 ttaccgaatc tgaacaatgg gatacggtaa tagagggaaa cgatgacctt ttagagaaat
    77821 atatgtccgg taaatcatta gaagcattgg aactcgaaca agaggaaagc ataagatttc
    77881 agaattgttc tctgttccct ctttatcatg gaagtgcaaa aagtaatata gggattgata
    77941 accttataga agttattact aataaatttt attcatcaac acatcgaggt ccgtctgaac
    78001 tttgcggaaa tgttttcaaa attgaatata caaaaaaaag acaacgtctt gcatatatac
    78061 gcctttatag tggagtacta catttacgag attcggttag agtatcagaa aaagaaaaaa
    78121 taaaagttac agaaatgtat acttcaataa atggtgaatt atgtaagatt gatagagctt
    78181 attctggaga aattgttatt ttgcaaaatg agtttttgaa gttaaatagt gttcttggag
    78241 atacaaaact attgccacag agaaaaaaga ttgaaaatcc gcaccctcta ctacaaacaa
    78301 ctgttgaacc gagtaaacct gaacagagag aaatgttgct tgatgccctt ttggaaatct
    78361 cagatagtga tccgcttcta cgatattacg tggattctac gacacatgaa attatacttt
    78421 ctttcttagg gaaagtacaa atggaagtga ttagtgcact gttgcaagaa aagtatcatg
    78481 tggagataga actaaaagag cctacagtca tttatatgga gagaccgtta aaaaatgcag
    78541 aatataccat tcacatcgaa gtgccgccaa atcctttctg ggcttccatt ggtttatctg
    78601 tatcaccgct tccgttggga agtggaatgc agtatgagag ctcggtttct cttggatact
    78661 taaatcaatc atttcaaaat gcagttatgg aagggatacg ctatggttgc gaacaaggat
    78721 tatatggttg gaatgtgacg gattgtaaaa tctgttttaa gtacggttta tactatagcc
    78781 ctgttagtac tccagcagat tttcggatgc ttactcctat tgtactggag caagccttta
    78841 gaaaagctgg aacagaattg ttagagccat atcttagttt taaagtttat gcaccacagg
    78901 aatatctttc acgggcatat aacgatgctc ccaaatattg tgcaaatatc gtaaatactc
    78961 aactgaaaaa taatgaggtc attattattg gagaaattcc tgctcgatgt attcaagatt
    79021 atcgcaatga tttaactttt tttacaaatg ggcttagtgt ttgtttagca gagctaaaag
    79081 gatatcaggt taccactggc gaacctgttt gccagacccg tcgtctaaat agtcggatag
    79141 ataaagtaag atatatgttc aataaaataa cttagtgcgt tttatgttgt tatataaata
    79201 tggtttctta ttaaataaga tgaaatattc tttaatatag atttgaatta aagtggaaag
    79261 gaggagattg ttattataaa ctacaagtgg atattgtgtc ctatttgtgg aaataaaaca
    79321 agactacgaa tacgagtgga tactatactt aaaaatttcc ctttatactg ccccaaatgt
    79381 aagaacgaaa ctttaattaa tgttcaaaaa atgaatataa taacaatcaa agagccagac
    79441 gccaagacgc agagccgata atttgagaaa tgaaactctc atcttatcgg ctctttttgt
    79501 ttatctgaat tttactgact agccttcaat atttcttgct tcattgatac cttttgctag
    79561 tgcttccatt aaggatagtt ctttgtctgt aaagctatcc atgtattttt ctacctgtaa
    79621 ccttcgagtg cttttaatca aattatctgt aggtaagaaa aattcatcaa tagatacatg
    79681 gagtaatgat acaagatcat acagcacttg tgtacttggg tgttgtcctt tgttttctat
    79741 atttgttaaa taacgtgggt caatttcaat cattgttccc acttgttcac gagtgagacc
    79801 ccgtttcatt cgagcctctt taatcgctaa accaacggct ctaaaatcgt atttatcttc
    79861 ttttttacgc atactaaatc acctctatac attttactgt tcctatataa ccataaacag
    79921 gtatagaaaa acatgttata tagtttatga gttcctatag aacactgtgg aatttattaa
    79981 tgcgatgaat ccaatttcaa atagaaaggt cgctgatttt atttacctat acaactttat
    80041 aaaatttagt catactccta gaaagtagat aaaattggcg acttaatgga gggaaaagtc
    80101 gccatgagaa agataatctg tcatctagtt ctcttaatta agttcttatc aaaaaaactt
    80161 atccacctgt actggataga tatgaccatc aatgtggttt tgcagattac atagatagaa
    80221 aaatcaaagc atatgaacag agaaaacaat ctgtttatgt gcttttttgg tcacttaata
    80281 aatatctttt aggatttctc ttcatttatg caacaaatcc ccctttcgtg tcggggttta
    80341 gtatgaaggg agataaagaa gcacatgcca ctccctttca cgacagaaag ggggtgaaaa
    80401 gcatgaaacc atcttctttt caagaaacca tagaaaatca gtttgactat atctgcaaac
    80461 aagttattga agatgaacga aaagattact tcaaacatct agacagacta tcagcaaaag
    80521 aagtctcgtt ttctgatata gataactacc ttgtcaactc tttttctact gttgatacgt
    80581 acgtcactga tttccaacta tttaaattat ttggattaag aatcaatgtt gaaagtgatt
    80641 tattaagtga agccctgcgt catctttcag agaaaaaacg gaacattatt ttacttcatt
    80701 actttatgga tatgagtgat gtggagattg cggagttact aaatttgaat cgttcgactg
    80761 tttatcgtca tcgaataagt ggactagcca tgattaaaga attcatgaag gagtgtaaag
    80821 aatgaaaaca gcttatccaa gggttccctt ccccctcatt gtaaaggcga cagatggcga
    80881 cgtggaagca attaatcaga ttgttaaaca ttatcgaggg tatacctcaa aacgttcatt
    80941 acgtcgcatg acagacgaat atggaaattc tcatatggtt attgatgaaa ccctacgtgg
    81001 cagaatggaa acgaaactca tctctaagat tttatcgttc gaaattaaat agtcccattt
    81061 tttcgtggaa gcgtgtcgaa tcgtatccac gcttcccgat ttgggaggtt tgttattcca
    81121 tcaaagcata ttgtgtgttc agtaggtttt gataggctaa caagccaaac gttctttgac
    81181 aaccaaataa aggcaatcga atacgtttcg gtaagaaaag agctgatgaa ctaacacgcc
    81241 atgacctaca aaattagtga gcgattcatg ttagtaattc gaaagtaatc tttagcagga
    81301 ttgctgccat gactttctta tcgtgataat gatactcccg tatagccata gtccgagcgt
    81361 tagaagcgtc acaggcaatg ggtacggcta catgagaacc atgcagaagt gaaattcctg
    81421 tgagctttgc tagagctgtt cgattgctaa gatattcttc tcttgtcagt gtattattat
    81481 aaaactattt gatataatta taggtgaata ttggagtttt cctagcctat aattgggaaa
    81541 ggagtaataa tgataacggt cacaaaaaag gatttagttg agctaggata tggaacttct
    81601 ttttcagcag acatcataaa aaaagcaaaa gaattgatga ttacaaaagg gcatatctac
    81661 tatcaatctc gaaagctaga tagagtccct cgtgaagctg ttgaagaaat tctaggaatt
    81721 cggttttcaa atgaaaacag gtctgagtag tttttgcaca gtaaggagta aaaactatgg
    81781 ttaaagaccc aataaaaaaa gcaaagaatg gaacctatta ttttcgtgca aatctaggtt
    81841 atgattctaa agggaaaaaa attcaaaaat atcgtagtgg attcactact aaaaaagaag
    81901 caagagaaga atattcgaaa ctgctattga tgaaaccaga agaattaagt gagaataagg
    81961 ataaaatgac gtttaaacat tatatctttg aaattttcct tccatggtat aagacacagg
    82021 taaagctcag aacatatgaa aatcgcttac caactattaa gaagcatttc tcttattttg
    82081 ataaaatggc tgtttccgat attgagccta ttgatgtgca aaattggcaa ctaaaattat
    82141 caaagaagtg taagtcttct tatgtaagag ctgttcaagg actattttca gttgctatgg
    82201 atcgagcaat tgtccttggg ataaccacca caaatccatc taagattatt ggcaatgtga
    82261 aaaagcaaaa gtctaaaatt gaattttgga caaaagaaga atttgaaaaa gtaatctctc
    82321 taatttacaa agaagattac tatcaacact ttttatttat ctctctgtgg tttttattta
    82381 tgactggaat gcgaattggt gaagctactg ccattcaatg ggaagatatt gattttgact
    82441 caggagtact aaccatcaac aaaacactct attacaagaa tcaatcgaat tatagatttg
    82501 ttgaaccaaa aacaaaggcg agcgttcgtc atattgtatt agataaatgc acattaactt
    82561 atttatccga atggaaggaa gtacaacaaa atctaattca gacagacttt gtaatgagct
    82621 ataacggtat tcctacccaa aaacatacac tatcatatgc tattgaacgc tatgctaagc
    82681 tggctggtat ccatcgaatc agaatccatg ggttacggca ttctcatgct tccttgttaa
    82741 tcagtatggg agaaaatcca cttatcatta aagatcgtct aggacacgaa gatattgaga
    82801 cgactttagg aacgtatgga catctttatc ctaacagtaa tttcgaggta gctaacaaat
    82861 taaatggagc catttccttt aaagaagcaa aacaaaatta tgatacttca ccaaagaatc
    82921 aatttactgt agactacttg cgaaacaaag aaatgaaaaa agtgcaataa aagtgcagta
    82981 aaaagataag aagagccaga aacccttggt ataagaggat ttctagctct cctacaacta
    83041 ttcccactcc actgttgctg gtggtttaga agtgatgtca tacacgatac ggttgacgtg
    83101 ggctacttcg tttacgatac gtacagagat tttttgcaag acttcccatg ggatacgggc
    83161 aaagtcagcg gtcattccgt cgattgaagt tacagcacgg ataccgactg tgtagtcgta
    83221 agtacgtccg tcacccataa caccgacaga gcggatccct ggaagaacag tgaaatattg
    83281 ccagatatca cggtcaagtc cagcagctgc gatttcttca cgcaagatag catcagattc
    83341 gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga acacgaatac caagaccagg
    83401 accagggaat ggctgacgcc aaacgattga atcaggcatg cctaactgag tccctaattc
    83461 acggacttcg tctttgaata atgtgtttaa tggttcgatc aattcaaatt gcatatcttc
    83521 tggcagtcca cctacattat ggtgagattt gatcgtctgt gctgtttctg taccagattc
    83581 gataacgtca gtatacaacg ttccttgtgc taggaaagag acgccttctt caccagcaag
    83641 ttttgttgct tcgtcatcaa aaacatatac gaattcattc ccaatgattt tacgtttttg
    83701 ttctgggtca gatacacctt tcaacttgtc taagaagcga tctcttgcat cgactttgat
    83761 gatgttcaag ccgaattttc cgcctagact ttccattact tgttccgctt cgcctttgcg
    83821 tagcagaccg tggtcaacaa agatagatgt caattggtca ccgatcgctt tttgtaaaag
    83881 aaccccaacg acactagaat caacgccacc tgaaagacca agcaagactt ttttgtcacc
    83941 aacttgttca cggatttttt ctacttgcat atcgataaag ttatccattg tccagttacc
    84001 ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat tcgattccgt attcggaatg
    84061 acgtacttct gcatggaatt ggataccata aaaattacgt gttgtgtctt ggatagaagc
    84121 aatcggacaa tctttgcttg ttccgactgt ttcaaagcct tcaggaactt tagttaccaa
    84181 gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt tctttaaaca agacagcttg
    84241 atcgcttgtt acttctaaca aggctttccc atattcgcgg tttttagcag gctctacgga
    84301 accgccaagt ttgtacgtga tcaattgcat accatagcaa atccctaata caggaatacc
    84361 taaattgaag atctcaggat cgatcccaaa tgcattctca tcatatacac tgtttggtcc
    84421 gccagaaaga atgattccct ttggattcat cgcttttact tcttctgcag taatgcggtg
    84481 gctcaataat tcggaaaaga ctccaagatc acgaatacgt cttgtgatca attggttata
    84541 ctgactaccg tagtctaata cgataatctt ttcaacgttc gtcatatcgg caacgtttgt
    84601 caaatttatt acccctatcc ctttaaattt tatctcaaaa tagtcaaact attttaaaat
    84661 gctaatattt tcgcatgaaa atcgaatcga tgatatgatt ttcagtttta tggagaatta
    84721 tatcggctct tcctcgtgta ggcaagatat attcctgtaa atttttcaaa ttcacatttt
    84781 tccatacatc ttttgccatt ttaaaggctt cttcacgatc tccgatagca aaacgataat
    84841 aataattctc tggattttgg aaagccgtat ccagtaacgc accaaaacga tccaaatacc
    84901 atttttcgat cagcacggga tcggcatcga catagacaga aaaatcaaaa aagtcgctga
    84961 cgtagatttg ctgattcgca ggtaattgaa gcgtattgat cccctcaacg atcaagatat
    85021 caggctgctg gatcaattcg tacttgtctg gaatgatatc atacacatca tgtgagtaaa
    85081 caggtacttt tatctcttcc tgaccagatt ttacacggtt caagaaatcg atcagcatct
    85141 ccatatcata actttcagga aatcctttac ggtccatgat tccacgctct tttaatatac
    85201 gatttggata aagaaatccg tcagtcgtga tcagctgaac gtttcttcgt ttgaaggtac
    85261 gagacaaaat cgtctgcagc agtctggctg ttgtactttt tccaacggct acacttccgg
    85321 cgatcccgat aataaaaggc ggtacttcta cgtatttatg aagaaataaa cctttactca
    85381 agaacaaaga ttcaaattct ttcatataaa gataaatcag atgagcaaga ggtacataga
    85441 tatctcgaac atcctgcatg gaaatgcggt cattcaaact tttgatatta tctagttcat
    85501 cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg ccattcttct cttgccacac
    85561 ggtagtagtt cattggatca ttcatattag cctcctgcgt tctcccatca atggaactat
    85621 tttaacacaa aataaacgca aaccccacca cttaagagag attgccgatc tttttgtata
    85681 atctttataa tagaaagaaa cggagtctta ttcttgactt gcgcacggat acataaaagg
    85741 atagactgtt gtcatgaaag aaatgagaag gatggaagac atgacaaatc attactattc
    85801 tgaacgccca gatacggcgc acgattttga acaatgggct tttgagttaa aaggcagaac
    85861 ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa acagtggatt atggttcacg
    85921 tgtcctgatt gatgctttcg attgggaaga gttacctgat gaaggaaaga tcttagatgt
    85981 gggatgcggg tatggaccga ttgggttagc tttggcattt gcgacacagc ggtttgttga
    86041 aatggtcgac attaatgaac gagcggtaag tctagcgcaa ggaaacgcaa agcgtaacca
    86101 aatcgaacat gttgatatcc atcaatcgaa tatctatgaa gcagttcatg aagaaaccta
    86161 tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa aaagttgtac atgaaatttt
    86221 gacaggcgca tatcctcggt tgaagaaggg cggtacactg acaattgtga tccagaagaa
    86281 acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca tttggtaatg cagaaatcgt
    86341 cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa gaataactag ctgaaaaata
    86401 gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg gtacgtatca gttctttttt
    86461 tgttgagaag tttttaaaaa caaagaacta ttttttcttc aaaaagaaat agtaggaaca
    86521 gagtcgttgt tttttacgat aaaataaata agatacagaa cttgtataga aggctgccaa
    86581 gtcggtagat aaaggaggtt tttatcaaaa aacatacttt ccttttttct ctattctttt
    86641 cttgggggtt ttggtacact gatagggaat ttagatagaa gggagccaat aggatgaagc
    86701 tgaccatcag agatatcgca gaaatggcag gcgtatcagt aacaactgtc tcacagattt
    86761 tgaataacaa aggaagcaga tttagtgata agacaagaaa aaaagtgttg tcgatcgtga
    86821 atgaacatca ttataagccc gattatttcg cttcaaatgt gatcaatcga cattcaaaga
    86881 ccatcggaat gatcgtccct gatgtcactg atttcttctt ctccaaactg atcgaaggtg
    86941 tagagagcta tttgaatcct ttgggctatg tgatcatgtt atgcaattct cgtcatagcc
    87001 aagaaaatga gatcaagtat ttacaagagc tttcccaccg ctcagtggac ggaatcttgc
    87061 tggccacacc aaatatttta cctgagaaat atgcattaga cagcggtttt tatcaaaaaa
    87121 tgccaatcat tttaatcgat cgcggattga atcgtcggga taacggacgg cttatcgtaa
    87181 aggaatatga gggcgcctat caagctgttt cgctgtttat tgaaaatggc catacgaaga
    87241 tcggcatgct gaaggaaacc actggatact atcaattaga agaacgtttc aacggatatc
    87301 gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa atttgttgaa catggagagt
    87361 tgactgtcca aggtggatat actgcatcaa aaaaattact caaacataaa gatatcacgg
    87421 ctattttttg cgggaatgat gccatggcga tcggatgcta tcaggcgatc gatgaattgg
    87481 gcaaaaaaat cccagaagat atctcagtca taggattcga tggattaaag ctgtcagaat
    87541 acatgattcc gcaattgacg acagtgcagc agccaagttt tgatattgga ttttatgctg
    87601 cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa agttccgaac aaagtgttcg
    87661 aaacaaaatt aattattcgt gagagcgtaa aagtattgac aaagggctaa ctcggcggta
    87721 tattgcttat gtaagcattt acaaaggcta gttagtgctt tttttatttt tagtaaacca
    87781 gtttactaaa gtggtttacc tttcctaaaa ataatgtata ataccgaatg aagacaagga
    87841 ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag agggatggaa acgagctgtc
    87901 gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat ggaaagattc cagattatca
    87961 agtcagtgca ttattgatgg caatttttta tcaagacatg acaaatgaag aaatcacgaa
    88021 cttaacattg gcgattgcta attctggtga tgtcatcgat ttgagttctc ttgaaggaat
    88081 aaaggtagat aagcattcga caggtggcgt tggtgacacg accacattga ttttagcccc
    88141 cctagtagct agtgtcggag tgacagtggc taaaatgtct ggacgcggtc taggttacac
    88201 aggtggtaca ctagacaagc tagaagcaat tcccggattt cagatcgagc tttcggatga
    88261 agaatttgta cgcattgtta atgaaagtaa agtagcggta attggtcaat caggaaactt
    88321 ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc acagcgaccg ttgattctct
    88381 tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg gcaggagcag atgcaatcgt
    88441 tttggatgtg accactggag acggtgcttt catgaagaac atcgaagatg caagacgtct
    88501 ggcaaagacc atgacgagca ttgggaaact ggctaaccga gaaacagtgg cggttatctc
    88561 agatatgtca gaacctcttg gcgaagctat cggaaatagt ctagaagttg tcgaggcaat
    88621 cgaaacatta caaggaaatg gtccagaaga tctagtagaa atgtgctacg ccttaggaag
    88681 ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat gaagcaagaa cgttgcttca
    88741 agaagctctg gaatcaggta aagcgttagc aaaattcaaa gaaatgatcc aaaatcaagg
    88801 gggagaccca gcgatcgtgg aacatccaga acgaattttg actgcacgct acacaatgga
    88861 gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg gcaaatgaat taggaattgc
    88921 tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa gatattgatc acgctgttgg
    88981 attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa ggtgagtcac tattgacgat
    89041 ctatagtaac gacgaagaaa tcacttctgt cattgaatta ttatataaaa atattgaaat
    89101 tggtgaatcg gcaatgaagc caacgttgat tcatgacatc atcacagaat aaaggaaaaa
    89161 agcggacttt accgttttaa agaaaagggg aaaagaaatg gaactaaacc gaatgatcga
    89221 ccatactatt ttgaaagcag acgcatctaa agaagctgtg atgcaaatta tcgaagaagc
    89281 aaaaaaatac catttttatt ctgtctgcat caatccagca tgggttgcgc tagcgaaaga
    89341 acaattacaa ggtgagccag tagccgtatg tacagtaatc gggtttcctc taggagcaaa
    89401 cacacccgag acaaaagcat ttgaaacaac agatgccatc aataacggtg cagatgaagt
    89461 cgatatggtc atcaatatcg gtgctttgaa atcaaaggat gatcaacaag tccaaaaaga
    89521 tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt gtcaaagtta ttattgaaac
    89581 atcgttatta gatagagaag aaatcatccg agcttgcgaa atagcaaaag ctgcaggcgc
    89641 tgattttgtc aaaacatcaa ctggtttctc aacaggcgga gcaaaggtag aggatgtccg
    89701 tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa gcttccggcg gtatccataa
    89761 cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca agaatcggaa caagcgcagg
    89821 agtagcaatc gtatctggtt caactggtga aggctattaa ttttttcaaa ggagaagctc
    89881 atggcagaac tcaaacaaga atggatcaac acagctattg aagcgttaga taaagcctat
    89941 gttccttatt cccattttcc ggtaggcgct tgtctcgtaa cggaatcagg caagatttat
    90001 caaggcatca acattgagaa tgcatcattt ggattaacga attgtgccga gcgcacagct
    90061 tttttcaaag cagtatctga aggagaaaaa acatttacgc atctagtcgt agcggggcac
    90121 acccccgatc ctatctctcc ttgtggtgca tgtcgacaag taatggcaga attctgttcc
    90181 cctgatatgc cggttacgct agtaggagac aatggtgtga cgaaggcaac gaccgttcgt
    90241 gcactgctgc cttatgcatt tactgaaaaa gatctataac tcatgttcat tcagtcagct
    90301 gactgttgaa aaataaaaca attattttag gaggctttac agaaatgaaa aaagcaaaat
    90361 tatttggttt aggtgctgtc gcactagcag cagggttatt tttaggtgca tgcggcaaca
    90421 acggctctac tgattcatcc ggtggcaaaa gctcatcaga cacaacaact gcagcattga
    90481 tcacagacac aggtggtgta gacgaccgtt cattcaacca gtcagcttgg gaaggactag
    90541 aaaaatgggg gaaagatcaa ggactttcac gaggaaatga tggcttccaa tatttccaat
    90601 cttcaaatga atcagattac atcccaaata ttgaccaagc attgaatgct ggattcaaaa
    90661 cgatttttgg tattggttat aaactaaaac cagcgatcca agaacaagca acaaacaata
    90721 caggtacgaa ctttgttatt atcgatgatg tcatcgatgg attagataac gttgtatctg
    90781 caactttcaa agacaacgaa gcttcttatc ttgcaggtgt tgcagcagct tatacgactg
    90841 aaacaaacgt agtcggcttt atcggcggtg taaaaggtga agtaatcgat cgttttgatg
    90901 ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt aggaaaagaa atcaaagtat
    90961 tgaatcaata tgctggtgac ttctctgctc cagataaagg acgttcaatt gctcaaggta
    91021 tgtatgcaca aaacgcagat atcatcttcc atgcttcagg cggtacaggt aacggtgtat
    91081 tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa agtttgggtt atcggtgttg
    91141 accgcgacca atcagacgaa ggcgaataca cattaaacgg cgaaaagaaa aacttcacat
    91201 tgacatctac actgaaagca gttggaacag tagtagaaga tttggcacaa aaatcagcgg
    91261 acggtaaatt ccctggcggc gaacacactg tttatggatt gaaagaagac ggtgttggtc
    91321 taacagaagg acaactttct gacgaagcga aaaaagcagt tgatgaagca aaagaaaaaa
    91381 tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga aaactaaaac catttctata
    91441 gccttgttag acacatgttt gacaaggcta tggtttgatt agaacaagaa ttgttcattt
    91501 atccaagctg ccttgtgaca gtttggataa gggaacaact ccctgaagta atgtttgttt
    91561 caaaagaaga acgctcacta agcgtgaatc ttagtcaatc gttgccctag atagaaatcg
    91621 ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca tagaaatgca gaatattacc
    91681 aaagaatttg gaacattcaa ggcaaatgac aacatcaatt tacaagtaaa ggcaggagaa
    91741 attcatgcgt tgcttggaga aaacggtgct ggcaaatcta cattgatgaa cgtgctttcc
    91801 ggattattag agccgacatc agggaaaatt ttgatgcgtg ggaaagaagt aaagatcaca
    91861 agtccgacca aagccaacca attagggatt gggatggtcc atcagcactt tatgcttgtt
    91921 gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg agcctagtcg cgcagggatg
    91981 cttgaccata aaaaagcacg aaaagagatc caaaaagttt ctgaacagta tggattgtca
    92041 gtcaacccag atgcttacgt tcgtgatatt tcagttggaa tggaacaacg ggtagaaatt
    92101 ttaaaaacac tttaccgagg agcagatgta ctgatttttg atgagccgac agctgtattg
    92161 acccctcaag aaattgatga attaatcgtg atcatgaagg aattagtcaa agaaggcaag
    92221 tcgatcattt tgattacgca taagttagat gaaatcaaag cagtagctga ccgctgtaca
    92281 gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta aagacgtaac ctcacaacaa
    92341 ttagccgata tgatggttgg aagaacggtt tcattcaaaa cgatgaaaaa agaagcgaag
    92401 cctcaagaag tcgttttgtc tattgaaaat ctagtggtga aagaaaatcg tggattagaa
    92461 gccgtgaaaa acttgaactt agaggttcgt gctggcgaag tacttggtat cgctggaatc
    92521 gatggaaacg ggcagtcgga gttgatccaa gctttgactg gtttgcgaaa ggcagaaagc
    92581 ggacatatca agctaaaagg ggaagacatc actaataaaa aaccccgaaa aatcactgaa
    92641 catggtgtag gacacgtgcc agaagaccgt cataaatacg ggttagtcct agatatgaca
    92701 ttatctgaaa atatcgcact acaaacctat catcaaaaac cttacagtaa aaacggcatg
    92761 ctgaattatt cagtaatgaa tgaacatgcc agagaattga tcgaagaata tgatgttcga
    92821 acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg gaaatcagca aaaagcaatt
    92881 atcgctcgtg aagtcgaccg agatcctgat ctgttgattg ttgcaaatcc aactcgtgga
    92941 ctggatgtag gtgcgatcga atttattcat aaacgtctga tcgaacaaag ggacaaatac
    93001 aaagcagtgt tactgatcag tttcgaatta gaagaaattt taaatgtttc ggatcgtatt
    93061 gctgttatcc atgaaggaga aattgtcggt atcgttgatc cgaaagaaac atctgaaaat
    93121 gaattaggtc tattgatggc gggctatacc ttagaagaag cacgaaaaga gttagaaaag
    93181 ggggctggcg cacatgaatg atcgcagcga aaaattccgt aatttattag tgcctgtact
    93241 ttcagttgtt ttaggattga tcttaggcgc gatattgatg gctgcttttg gttttcagcc
    93301 catccaaggt tattcttcta tgctagatgc agcccttggt tcgcaaagag ggataggtga
    93361 aacgttaagg caagcaacgc cgttgatttt tacagcatta ggtttttctg tagctaactc
    93421 agctgggttt ttcaatattg ggctttctgg acaagcactt tgcgggtgga tcgtcagtgt
    93481 ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt ttgcttccgt tatgcgtgat
    93541 cttaggtgcc ttagctggtg cgatggcagc ggctgttcca ggtttacttc gagcattttt
    93601 tggaacaagt gaagtgatcg taacaatcat gatgaactat atcttattat acgtaagcac
    93661 atttgcttta catgaagtga tgcctgaaag ctatcgctca agtttggact cttccaatat
    93721 gatcagtcaa aatgcctcac tgcggttacc atggttaaca caagcttttg gcggctctcg
    93781 cgtaaactca ggattatttt tagcaatcat cgcgcttatt ttcgtttggc tgctgatgaa
    93841 gaaaacgact ttaggatttg aaatccgttc tgttggattg aatccttttg cttctgagta
    93901 tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg gtcatttctg gcgctttggc
    93961 agggcttggc ggtgtggttg aaggattagg aacgtatcaa aacttctttg ttcaaacgac
    94021 ttcgctatct attggatttg acggaatggc tgtttccttg cttggttctg gatcagcaat
    94081 cggtattctt ttatcagcga tcttgttcag tattttgaag atcggtggac ttggcatgca
    94141 gacaggagca ggtgttccgt ttgagatcgt caatgtatcg attgctttga ttatcttctt
    94201 tgtcgggatc aacttcctga ttcgtttcgt catggctaaa gtcttccaag ggaaaaaaca
    94261 agaagagatc gttgcgacaa tagaatcgaa accaacgaat caaaaccatg aagggggcga
    94321 actataatgt cgactatcga attaattgcc ttgatcctta cttctacact ggtttattca
    94381 acaccgctaa ttctaacgtc actaggcgga actttttctg aacgaagcgg gatcgtaaac
    94441 gtagggctag agggaatcat ggtcatgggt gcttttagtt ccatcgtttt caacttgacg
    94501 atgagtccat cacttggttc tatgacacca tggatcgcta ttttagtggg tggcgtcgta
    94561 ggtatcctat tttctctgat tcacgcagta gcaacagtca gtttgcgtgc tgaccatatt
    94621 atcagcggga cagtaattaa tctgatggca cctgctttag gtgttttctt gatcaaagca
    94681 tggtatggta aaggtcaaac tgataacatc acgcagaatc tggggtattt ttctttccca
    94741 ggattagcag atattccggt cattggacca attttcttta aaaatacatt cttacctgct
    94801 tattgtgcta ttttgattgc tgtcctagct tgggtgatca tcttcaagac gaaattcggc
    94861 ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg acacattagg tatcaatgta
    94921 tatgctatgc gttattcagg cgtactgatt tctggcttgt taggcggtat gggcggtgct
    94981 gtttttgctc agtcgatttc cggtaacttt tcagctggta cgatcgttgg acaagggttc
    95041 atctccatgg ctgctatgat ctttggtaag tggaatcctt taggggcaat gggtgcctca
    95101 ttgttctttg gttttgctca aagcttgagt atcattggcg cacaattacc agttatttct
    95161 tcgattccgc cagtattgct gcaaattgct ccatatttgc tgacaatcat tgtgctggtt
    95221 gttttcttag ggaaagcttc tggtccaaaa gcaaacggga agaactatat caaatcaaaa
    95281 taatctttta gcgaataaaa agggtgggtt acgggaagtg tttttcgtct cgcccttttt
    95341 gttttaaagg caataaaaat aaaaagaaag aaggaataat catgtttaaa cgcgtacatc
    95401 tgatcgtcat ggattcagta ggaattggag aagcaccaga tgccgataag ttcggtgatg
    95461 ttggttctga tacattagga cacattgcga aagaagcagg attgaacgtt ccacatttag
    95521 agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt ggaatcagtg aaagatcatc
    95581 aaggctatgc gacgaaatta gaagaagttt ctgtagggaa agatacgatg acaggccact
    95641 gggaaatcat gggattgaat atcaaaactc catttcgtgt gtttcctaat ggattccctg
    95701 atgatctgat caaacaaatc gaagaatttt ctggccgtaa agtcgtatgt aacaaacctt
    95761 atagcggaac agctgttatt gacgattacg gtgaacacca aatgaaaaca ggcgatttaa
    95821 ttgtatatac ttctgccgat cctgtccttc agatcgcggc acatgaagaa atcattcctt
    95881 tagaagaatt atatcggatt tgccaattcg ttcgtgatat aacaaaagat gatccgtata
    95941 tgattggccg aatcattgca cgtccgtacg tgggtgaacc aggagacttc acacgaacaa
    96001 gcaatcgcca tgattatgcg ttgaatccat tcggacacac agtccttgat tctttgaaag
    96061 aagcaggaaa ggacgtgatt gctgttggaa agatcaacga tattttcaac ggacaaggaa
    96121 tcactgaatc tgtccgcacg aaaagcaata tggatggcgt tgaccagctg ctgaaagtta
    96181 tgaaaaacga tttttcagga atcagcttta ccaatttagt agattttgat gcattatacg
    96241 gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga agaatttgac ttacgaattc
    96301 cagaattgct tgaagcgatg gaagaagacg acttgctaat gattacagcc gatcacggaa
    96361 acgatccgac gtttactggt accgatcata cgcgagaata tgtaccgtta ttggtttaca
    96421 gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata ttattcagat atttcagcaa
    96481 cgattgctga gaactttagt gtttcttcga ctgaaaatgg cgaaagcttc ttgaaattat
    96541 taaaataatc tttttaaata ggagaaagca aatgaccaag ttaagcgaga tgttacaaga
    96601 aacgacccag tttatccttg ataaaggagt aaaagaaatt gattttggtt tgattctagg
    96661 ttcaggatta ggtgaattag cagatgaaat cgaagatgct gtaatgattt cttatgatga
    96721 gatcccgttc tttcctgttt cgacagtagt tgggcatgca ggaaagctag tttatgggtc
    96781 tctggcaggc aagaaagtgt tagccatgca agggagattc cactactatg aaggtcattc
    96841 catgcaaaca gtgacctatc cagtacgtgt gatggccgga ctaggggccc attcagtcat
    96901 tgtgactaat gcatgtggtg gtgtcaacga atcatttgta ccaggagatt tgatgctgat
    96961 taccgatcat atcaatttta ctggtgaaaa tcctttgatc ggtccgaatg aagatgcaat
    97021 gggccctaga tttccagata tgagtcaagc ttatacgcct gactatcaag caacagcaaa
    97081 agcagcagca gaaaaactag gtttggatct taaagaaggc gtatatatgg gctattctgg
    97141 accaacttat gaaacgcctg cggagatccg aatgtctcgg acaataggag ccgatgcagt
    97201 agggatgtcg actgttccag aagtcatcgt agcagctcac agcggattaa aagtgttagg
    97261 aatctcttgt attaccaact tagcagcagg tatgcaagcg aatctgagcc atgaagaagt
    97321 tgtagaaaca actcagagag tcaaacaatc ttttaaagca ttggttaaag aaacattgac
    97381 attattgtaa taggaggaac aataaaatga gtgtgcatat tgaagcgaaa gaaggcgaga
    97441 tcgccgataa gattttactt ccgggagatc ctttgcgagc taaatatatt gcggagactt
    97501 ttttggaaga tccagtttgt tacaatcagg tacgcggtat gttaggcttt accggcaaat
    97561 ataaaggaga acgtatttct gttcaaggaa caggaatggg aatgccatca gccaccatct
    97621 atgcccatga attgatccag tcgtatggtg taaagaaatt gattcgagta ggtacatgcg
    97681 gtgcattgtc aaaagacgtc catgttcgtg atttagtact agcacaaggt gcagcgacca
    97741 gttcttcgat gatcgaaaaa aatttccaag cctttcattt tcctccaatc agtgatttca
    97801 atctattact gaaagcatat gagatagcta aagaaaaggg ctatacggtt catgtaggaa
    97861 atgttctttc ggaagattct ttctacaaag atgatttgac agagacgttc caattagctg
    97921 aacttggcgt tttaggagtg gaaatggaag cagcggctct ttattactta ggcgcgaaat
    97981 accatgtgca gacattaagt ttgatgaccg ttagcgacca tttgatcacc ggtgaagaaa
    98041 caacagctgc agaacgtcaa tctacgttca atgaaatgat cgaagtagga ttggaaacag
    98101 cgatagcaga ataagaagga aatgaaaaag ctgccctgca ttaagtaata agaacatcca
    98161 agcaaaaata gctcctcatg tttttgactt ggctggactt attattgcaa atgtaagctt
    98221 ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta actctgagtc acaaggaaca
    98281 atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg agaagttggc
    98341 aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa tcgtgtcaca gtcccttttt
    98401 tatagtgttt tttataggta gtatttttta gcaactgtta agtcatcatt taattcataa
    98461 acaagtggtt gacctgttgg aatttcaaga tccatgatgt cttcgtcaga gataccttcg
    98521 atatgtttag ctagggcgcg taatgagtta ccatgtgcag ctactaaaac agttttgttg
    98581 tctagtaatg ctggagcaat ttcatcttgc cagaatggca aagcgcgttc taatgtcact
    98641 ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca ttgcgtaacg acggtcattt
    98701 gctgcagaac cttcgtcagt ttcttccatt aatggaggaa gagtatcgta agaacgacgc
    98761 cagatgtgca cttgttcgtc gccgtatttt tcagctgttt cttttttgtt caaaccttgt
    98821 aatttaccat agtgacgttc gtttaagcgc catgatttga tttgtggtac ccaaagttga
    98881 tctgaatatt ctaagatcaa gttacatgtt ttgattgcac gagttaaaac agaagtgtaa
    98941 gcaacatcaa attcgattcc agcttctttg attttgcgtc cgccttcttt tgcttcttcg
    99001 attccttctg gtgctagatt tacatcagcc caaccagtaa attggttcaa tgcattccat
    99061 tcactaagac cgtgacgaga aaaaactaat tttggcatgt ttagctctcc ttttaagata
    99121 ggtttatatt tctgaaattt tcagttctgt tttattgtac aattttttgg aagagatttc
    99181 catcgaaaaa ttagataaga ttctatgaga aaacaagtag agaatataaa aaaacgaaca
    99241 gtgcccacgc aactgttcgt ttttaggtat tagatgcata attgctcgat ttctttttca
    99301 ggtaaattga tatatttata acatgttcca actgaaacac cgcattttga agaaataaat
    99361 tggatcgttt cttttttttc ataatagaga cgtcggattt ttttgatcgt ttttgcatcg
    99421 atttttggtc ttccgccgat ttttcctttt ttacgagctt catctaatcc aactaatgta
    99481 cgttctttga tcaatgcgca ctccatgttt gctaggtttt ccattaattg gaaatagatt
    99541 tttcccattt cgcgcgtatc gattccttca tcaagactaa tcaagtgcag cccgcgatct
    99601 ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt tgcctaatcg atgaagttgg
    99661 caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca ctgactccaa atgaacagca
    99721 gtagaatcat tttgttccac ttcatatgtc tcatggaaaa tttcttgaca accaaagtca
    99781 gataattgat caacctgagt tgttaaatca acgtcattta tggttgtgcg tgcataacca
    99841 ataattttca tggtgattcc tttctagcag tgattttcta actggatata acagtaaaaa
    99901 tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa ttttccgctg tcttttttta
    99961 ttggatgatc aagcagtttt tctttattta cgacggattg cgtcaagaat ctcaacgcct
   100021 ttttctgagc cgacaactac tttagaaacc atgtttagga aaagcccatg ttctactacc
   100081 ccaacaagtt catctaaata ggtagctaag ctttctggct gttcgatgac ttctagatgc
   100141 agatcaatga tgtaatgacc accatctgtg gttaagactt ctccgttttc gtctgtacgc
   100201 aagacgggtt ggaatctttt ttcttcaaaa atatgaagta gctgttggga gccataaggg
   100261 atcacttcaa ctgggagtgg gaacttccca agtttatcga ctaatttaga agaatcaacg
   100321 atccaaatcg tttcttttga gtacgtagcg actattttct cgaaaagcaa agcagcgccg
   100381 ccgcctttga tcccttgaaa atcagcactg atttcatcag caccgtctat tgtcaaatcg
   100441 actacgggga cttcatcaat actctttaac ggtattccta atttttccgc ttgttctttt
   100501 gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt cttcacgcat acggcgacca
   100561 atctcttcta ccatataata ggcggttgaa ccggtcccga gacctacgat catcccgtcc
   100621 tttacgaatt tcgcggcttc aatgccagct aattgtttta aattcatctt tgcgtccacc
   100681 tttttttagt ttgagcatcg tgctttcctc actattttag cgtgatttac ggtaaaaaga
   100741 taccattctt ttttattcca ataaagcttt ttcaaaaaaa attgcatctc ttgttgacat
   100801 gttttttcat tcgtgatatt ctaacaaagg tgctttatct acaggtttct gtgaagaaac
   100861 gtgctgactg tttatcaaag catatttgat aaggatgcag acattgcatt tattttttat
   100921 cacaaaaaaa gaaccacctg gatgtgtgga actagacgca aatcgtggga aggaggaaac
   100981 aaggaatgcc tacaattaac caattagtac gtaaacctcg taaatcaaag gtggaaaaat
   101041 ctaattcacc tgctttgaac aaaggatata acagctttaa gaaaactcaa actaacgtaa
   101101 actcacctca aaaacgtggg gtagcaactc gtgtgggtac aatgacacct aaaaaaccga
   101161 actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa cttaattgaa gttactgctt
   101221 atatcccagg gattggtcat aacttacaag aacacagtgt tgtattatta cgcggtggtc
   101281 gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg cggtgcttta gatactgctg
   101341 gtgttaacga ccgtaaacaa agccgttcta aatacggaac taaaaaacct aaagcttaat
   101401 tttaattatt aaacaaatga aacttgcttc tactatatag aagtaattac tatgaacaat
   101461 atttcggaag gaggagttac ggatgccacg taaaggtcct gttgcaaaac gtgatgtttt
   101521 accagatcct atttataact caaaattagt aactcgcttg atcaaccgtg taatggttga
   101581 cggaaaacgc gggattgcag ctaacattat ctataatgcc tttgacttga tcaaagaatc
   101641 tacaggtaac gatccattag aagtgtttga acaagcaatg aaaaacgttc aacctgttct
   101701 tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa gtaccagttg aagttcgccc
   101761 tgaacgccgc gttactctag gtcttcgttg ggtagtaaac tacgctcgct tgcgcggtga
   101821 acacacaatg gaagaacgct tagcaaaaga aatcatggat gctgcaaaca acacaggtgc
   101881 ttctgttaaa aaacgtgaag acactcataa aatggctgat gccaaccgtg cgtttgctca
   101941 ctatcgctgg taagattctc tctgtttggt cggcttttat aagtcgacct cagatagtgt
   102001 ccttattttt agcaactaga tagtaaagag aggagaaaca aggagaatga ccagagaatt
   102061 ttctttacaa aacactcgta atatcggtat catggcccac atcgatgctg gtaaaacgac
   102121 tgctactgaa cgtatcttgt actatactgg taaaatccat aaaattggtg aaactcatga
   102181 aggagcttca caaatggact ggatggaaca agaacaagaa cgtggtatta cgatcacttc
   102241 tgctgctact acagcacaat ggaagggtca ccgaatcaac atcatcgaca caccaggaca
   102301 cgtagacttc acagttgaag ttgaacgttc attgcgtgta cttgatggtg ctgtaactgt
   102361 tcttgatgca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc aagcaacaac
   102421 ttatggtgta cctcgtatcg tatttgcaaa caaaatggac aagatcggtg ctgacttctt
   102481 atattcagta tcaactttac atgaccgttt gcaagcaaac gctcacccaa tccaattacc
   102541 aattggtgcg gaagacgact tcacaggaat tatcgacctt gtaacaatga aggctgaaat
   102601 gtatacaaac gatcttggaa cagagatcga agaaacagaa attcctgaag aataccgcga
   102661 attagctgaa gaatggcgcg aaaaattggt tgaagctgta gctgaaactg atgaagaact
   102721 tactttgaaa tacttagaag gtgaagaaat cactgaagct gagttaaaag aaggtatccg
   102781 ccgcgcaaca gttaacgtag aattctaccc agtactatgt ggttcagcat ttaagaacaa
   102841 aggggttcaa ttactattgg acgctgttct tgattacttg ccatcaccgt tagatatccc
   102901 agctatcaaa gggattgacc ctaaaactga tgaagaagta gaacgtcctg cagacgacag
   102961 cgctcctttc tcagctttag catttaaagt tatgactgac ccattcgtag gtcgtttaac
   103021 tttcttccgt gtgtactctg gtgttttaca atcaggttca tacgtacaaa acgcaacaaa
   103081 aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat gccaactctc gttcagaaat
   103141 ctctgaagtt tacgctggag atatcgctgc tgctgttggt ttgaaagaca caactactgg
   103201 ggacacacta tgtgatgaaa agagtctagt tattcttgaa tccatggaat tcccagaacc
   103261 agttatccaa gtcgctattg aacctaaatc aaaagctgac caagataaaa tgggtgtggc
   103321 tttacaaaaa ctatctgaag aagatcctac tttccgtgct gaaacaaacg tggaaacagg
   103381 cgaaacaatc atcgctggta tgggtgaact tcacttagat atcatcgttg accgtatgcg
   103441 tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa gtatcttacc gtgaaacttt
   103501 ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag tctggtggta aaggtcaata
   103561 cggtcacgta tggattgaat ttacaccaaa tgaagaaggt gctggtttcg aatttgaaaa
   103621 tgcgatcgtc ggtggggttg ttcctcgtga atacattcca gctgttgaaa ctggtttgaa
   103681 agatgctatg gaaaatggtg tcttagctgg ctatccatta gtagatatca aagctaaact
   103741 ttacgatggt tcataccatg atgtcgattc aaatgaaact gccttccgtg ttgctgcttc
   103801 tatggcatta cgtgcagcag ctaagaaagc taatccagta atccttgaac caatcatggc
   103861 tgtagaagtt gttatccctg aagattattt aggtgatgtt atgggtcacg taactgctcg
   103921 tcgtggacgt gttgaaggta tggaagctcg cgctggcggc caacaagttg ttcgtgcgat
   103981 ggttccactt gctgaaatgt ttggttatgc tacaactctt cgttctgcta ctcaaggtcg
   104041 tggtacattt acaatgacat ttgaccacta cgaagatgta ccaaaatcag tacaagaaga
   104101 aatcattaag aaaaacggcg gaaaagctga ataatttctt aaaaccggat agtcctgcaa
   104161 agagattatc caaagagact atatttttaa tatagtttcg tgtaaaataa ttatcgatga
   104221 tatgggcatg tggtgtacct tgtgtacatc atatacctat cagacaaata aaaaatatat
   104281 tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa tttgaccgtt ctaaaccaca
   104341 cgttaacatt ggtactatcg gacacgttga ccatggtaaa actacattaa cagctgcaat
   104401 cacaactgta ctatctaaga aaaacggcgg ccaagctatg gcttacgatc aaatcgatgg
   104461 tgctccagaa gaacgcgaac gcggaatcac aatctcaaca gctcacgttg agtatgaaac
   104521 agatacacgc cactacgctc acgttgactg cccaggacac gcggattacg ttaaaaacat
   104581 gatcactggt gctgctcaaa tggacggagc tatcttggta gtttctgctg ctgacggccc
   104641 aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa gttggtgttc cttacatcgt
   104701 tgtattcttg aacaaagtag acatggttga tgacgaagaa ttactagaat tagttgaaat
   104761 ggaagttcgt gacctattaa cagaatacga attccctggt gacgatgttc ctgtagttgc
   104821 tggatcagct ttgaaagctc tagaaggcga cgcttcatac gaagaaaaaa ttcttgaatt
   104881 aatggctgca gttgacgaat acatcccaac tccagaacgt gacaacgaca aaccattcat
   104941 gatgccagtt gaagacgtgt tctcaattac tggacgtggt actgttgcta caggtcgtgt
   105001 tgaacgtgga caagttcgcg ttggtgacga agttgaagtt gttggtattg ctgaagaaac
   105061 ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa ttgttagact acgctgaagc
   105121 tggagacaac attggtgctt tactacgtgg tgttgcacgt gaagacatcc aacgtggaca
   105181 agttttagct aaaccaggta caatcacacc tcatacaaaa ttctctgcag aagtatacgt
   105241 gttgacaaaa gaagaaggtg gacgtcatac tccattcttc actaactacc gtccacaatt
   105301 ctacttccgt acaactgacg taacaggtgt tgttgaatta ccagaaggaa ctgaaatggt
   105361 tatgcctggc gacaacgtaa caatggaagt tgaattaatc cacccaatcg ctatcgaaaa
   105421 cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt ggtgccggtg tcgttacaga
   105481 aatcaaagct taattcactt aagttttaaa gtaaagcaac atttattcgg acgtaatcgc
   105541 tcggaacgaa ggtcttagga tctttgttcc gagctttttt atttattgca ggatcaggaa
   105601 aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt attttctaaa
   105661 tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg tgagtttata
   105721 tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta atcagaatga
   105781 tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca cgaacgagcg
   105841 tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga gggaacaaga
   105901 tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt ttagatcaat
   105961 cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct ggtccaattc
   106021 cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa tacaaagatt
   106081 cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg aacccaacac
   106141 caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac atcgaaatca
   106201 aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga atcttaggga
   106261 aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca gtaactgttg
   106321 tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat ggctacgaag
   106381 ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct gcgaaaggtc
   106441 atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa aatgttgagc
   106501 taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca ggagacatta
   106561 ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa cgccacggac
   106621 aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg tcaatgggtc
   106681 cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg ggtggcaacc
   106741 gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat gttatcttga
   106801 tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac tatcaaatca gctgtgaaag
   106861 ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca ttattcaaac
   106921 aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga attgaaccta
   106981 atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga caaggaacac
   107041 acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg cgtcaaaaag
   107101 gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga ggtggcgtag
   107161 tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt cgtcgtttag
   107221 caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca atcgaaggct
   107281 tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac ttatctatcg
   107341 actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta tcagcacgta
   107401 acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac gttgtatcaa
   107461 atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg cttgcataat
   107521 gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc ttgccatgga
   107581 tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag taaaacaagc
   107641 ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg tacgtgcgaa
   107701 attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag cgatcgttac
   107761 attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag cactaataga
   107821 taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc tacctcaaat
   107881 ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac acctgaaaaa
   107941 tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg catcactgta
   108001 cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa acgtaacaaa
   108061 gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc agctaacatc
   108121 gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa aggactagaa
   108181 gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa tgctcttcca
   108241 ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc tggtaaaggt
   108301 ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga aggcaaatac
   108361 gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg ccgtgctaca
   108421 atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc tggacgctct
   108481 cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa tgatcaccca
   108541 cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc tccttggggt
   108601 caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa acttattgtt
   108661 cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga gaggaggttc
   108721 accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat gaaaaaagtt
   108781 gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg ccgttcaaca
   108841 gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa acatgtacca
   108901 gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc tacaagaact
   108961 tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg gaggataaat
   109021 ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc gcacttcacc
   109081 tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag atgcaatttc
   109141 aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat tgatgtcagc
   109201 agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag taagcgaagc
   109261 ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag gatcagcttc
   109321 tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat aaggagggat
   109381 aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc cgcgactggg
   109441 atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat ttaagaatcc
   109501 gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa atcgaacgcg
   109561 caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt attggtaaag
   109621 gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt aaaagaatcc
   109681 atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta ggtgaaggaa
   109741 tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa gccatccaac
   109801 gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt ctaaacggag
   109861 cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat actttacgtg
   109921 cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta ggagttaaag
   109981 tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa ggagggaaat
   110041 aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa aaatgcgcgg
   110101 ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag ctgttgattc
   110161 acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc gttacatgaa
   110221 acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg ccaaagcaat
   110281 tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac cagtaaaacg
   110341 tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg aagcgttacg
   110401 tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg aaatgggtgg
   110461 tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg cttgatcaag
   110521 aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca ggtcaattag
   110581 aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa actgtgttgc
   110641 gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa ggaagaaatc
   110701 aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca attaccgttg
   110761 ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat tctaagaaat
   110821 acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga attatggaaa
   110881 ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa gaagcagtta
   110941 ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa aggaggatac
   111001 acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc gcacgtgaaa
   111061 ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc ggtgatgtga
   111121 tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt gacgtcgtta
   111181 aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca tatattaaat
   111241 ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga acacgtatct
   111301 ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt tcactagcac
   111361 cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt atgtttgtta
   111421 aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa ggcgttgtac
   111481 tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc gttaaaaaac
   111541 accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa gcgccaattc
   111601 atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt ggctacaaag
   111661 aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta gataaataaa
   111721 agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat cttaaagaag
   111781 taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca cctaaagttg
   111841 aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa aacttagata
   111901 aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca aaagctaaaa
   111961 aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa gttacattgc
   112021 gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta ccacgtgtac
   112081 gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat actttaggta
   112141 ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa gtacgtggta
   112201 tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag ttgttgacac
   112261 aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct aaaaaatcaa
   112321 tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact cgttgcgaac
   112381 gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt tgcttccgcg
   112441 aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa aaagtaaatt
   112501 cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag attttctaac
   112561 tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg catcaaaaat
   112621 taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg ttgaatacat
   112681 cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa acggcgaacg
   112741 tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg tcaaagctga
   112801 cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt ctgaaggtgt
   112861 tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg cttacgtatg
   112921 gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga aataaagtcg
   112981 ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca gttaaaggac
   113041 caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc gaaggaaacg
   113101 aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat ggaacaactc
   113161 gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa gcgttagaac
   113221 taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg aacgttggtt
   113281 actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta ccagctaaca
   113341 cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct gcaaacattc
   113401 gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt ggcgaatatg
   113461 tacgccgtaa agaaggtaaa actggtaaat aatcgtttag aaaaattgca tagaagccag
   113521 cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt ttacttgtgc
   113581 cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa taaaaataaa
   113641 gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa gagacatcgt
   113701 cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt ttttcgttct
   113761 aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct agcaagtgcc
   113821 tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca agctgtcggt
   113881 aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt tgaccgtggt
   113941 ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga aaatggacta
   114001 gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa catttggaat
   114061 tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt ggacgtcgtc
   114121 tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtaggg tttggtacag
   114181 gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg aagaaaaact
   114241 tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt gcttttagtg
   114301 gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct ggtggaccag
   114361 ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct ttaggctcaa
   114421 atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg aaacgtgcag
   114481 aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa ggaggacaac
   114541 aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc ctcaaaacca
   114601 acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg ttaagccttc
   114661 taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg ttgaagaaat
   114721 ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg aaacttcatg
   114781 aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt ggtacttcat
   114841 ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt tcaggcggcg
   114901 gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta ccaaaacgag
   114961 gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta ttgaaccgct
   115021 ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc gtgaaaaacg
   115081 aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta actgtgaaag
   115141 cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga tcaatcgagg
   115201 tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta gatcgaaaat
   115261 cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta ctgtaccagg
   115321 cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca tgttgaactt
   115381 ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt caccatacat
   115441 tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat ttgttgaatg
   115501 gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat atctgacatt
   115561 agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat acgctcaatt
   115621 aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga ttctaacagc
   115681 cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta tcggaaatgg
   115741 cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta tcagagaaat
   115801 ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg ctatttttgt
   115861 ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt tccaacaagc
   115921 tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta caagcagcta
   115981 tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta gttcgtttat
   116041 tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg aaaactggta
   116101 caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga tttatacgat
   116161 tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg agaaattagc
   116221 ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta aggggactga
   116281 agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct tccttggttt
   116341 agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat caatcggatt
   116401 aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga aacagttaga
   116461 aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg tgttgaggtt
   116521 tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac ctcattttaa
   116581 tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat gcttatggta
   116641 ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa acagctcttg
   116701 gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa gtaacaaatg
   116761 gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta ttagatggct
   116821 ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat ttgaataaaa
   116881 aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa cgtctagccg
   116941 gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac cctacaaaag
   117001 ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa gatgataaac
   117061 ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca atcttggctt
   117121 attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc gatgctgtat
   117181 ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg acttgcatta
   117241 tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc gacttctaga
   117301 gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt tccgccattt
   117361 tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa agaagatatg
   117421 attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa agttgaacta
   117481 gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca ttacatccgt
   117541 atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa ccgtggccgt
   117601 attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt atcatgaaag
   117661 taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt aaaggacgcg
   117721 ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa ttggaggtgc
   117781 tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg tagtagtttc
   117841 acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag ctgatgctgg
   117901 tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg ctatccgtgc
   117961 agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact tgaacatcaa
   118021 acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat tgcctgttcg
   118081 tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg ctatcgctgg
   118141 caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa aaaaagtgaa
   118201 tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc attctacatt
   118261 caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt ggtcatcagc
   118321 tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc aaatggcagc
   118381 agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag taacagttaa
   118441 aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag gtttagaagt
   118501 gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc caaaacgccg
   118561 tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg aacaagacac
   118621 ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca agaatcgcaa
   118681 aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa agagggtatg
   118741 ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca ggtgctgcca
   118801 tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa ggtgttagag
   118861 aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg tatggccaag
   118921 aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct ggcgatatta
   118981 tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt gtctctgaag
   119041 gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt caagcagatg
   119101 aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc tacacacctg
   119161 ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa gattttgata
   119221 aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca atgagtttgt
   119281 ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat gaagcaaaaa
   119341 atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg gaaatgacga
   119401 tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca ggaatcaata
   119461 ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt aacttaggac
   119521 gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt ttacgtaaag
   119581 aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa ctaggacgca
   119641 catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta atcaacgaac
   119701 gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa aaaatgatca
   119761 ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc gtacgtaatg
   119821 aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct ttacaaaaac
   119881 tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca cgcattttga
   119941 agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt gtctaaaatc
   120001 acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt ggaagatatt
   120061 tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag taagcactca
   120121 tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt tgaaggcata
   120181 aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata gtgttagtag
   120241 gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga aaagataaat
   120301 tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt tacaattgat
   120361 aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac acttgccaaa
   120421 acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa tcaaatattg
   120481 gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca aaatccagac
   120541 aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga aaatcaaggg
   120601 attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt tagaatggct
   120661 gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg tgttgccatt
   120721 gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac cagtatgcta
   120781 gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga agaaagtcaa
   120841 ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa tcggatacta
   120901 gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt ttctgctggt
   120961 cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa gagcgcactg
   121021 aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat ggtggattgg
   121081 ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca ccatttgaac
   121141 aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact gcattagtag
   121201 ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt gttaagccaa
   121261 caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat aataagaatt
   121321 taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca cagctattcg
   121381 aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc agcgaagaag
   121441 aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa agctatttgg
   121501 aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc gctggtgtgc
   121561 ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt gatccccagg
   121621 gcagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag atcactattg
   121681 tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc tatgtgttgg
   121741 aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac attgaatggc
   121801 taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa ttaatggcta
   121861 aagggatgaa ctttgctacc ttgcctttga cagctgaaga attagcagac gctatcgtcc
   121921 attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta tatgcctgga
   121981 gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt ttattttatc
   122041 ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt tttcacatta
   122101 ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat tcgcccattg
   122161 atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg cggagaaact
   122221 tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg cctctttatt
   122281 ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac tacaccgcct
   122341 ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt acggttccca
   122401 gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac attgatggac
   122461 gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg tgaaggaaac
   122521 ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt cagcagcttc
   122581 aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg tggggaagga
   122641 agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat cattgctttt
   122701 gtattattaa ctgtgctact gatcttttta agaggataaa cgttcagtgg gccgctatct
   122761 attcttttct tgctgatctg tttgcaagaa aggatgcaag cagtgtatga caagaaatat
   122821 tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa gaaagaacga
   122881 aaaaatttta tagaaaaatc attattccag ataacctttt aggaacaaag gagagaaaaa
   122941 catggtacgt tacaaagcaa tcattgcgta cgacggaaca aattttaatg gattccaaaa
   123001 acagccaaat gggcgtactg ttcaagaaga agtagaaaaa acattacaaa aaatggcaaa
   123061 tggaaaagaa atcacggtct ttggttcggg aaggacagat gccggagtac atgcgatcgg
   123121 gcaagtaatc cattttgatt atccagagga gcgtccgtta gaacgaatgc gtttcgcgct
   123181 agatacccag tcaccagagg atattgctgt aagacaagta gaaattgttt cagaagactt
   123241 ccacgcaaga tatttggtca aagaaaagac gtatcaattt cgagtggata tagggaaacc
   123301 acgcagtcct tttcgacgcc attatgcaag ttattttcct tacccacttg atttggaaaa
   123361 aattcagcgg gcgcttcctg atttattagg gactcacgat ttcacctctt tttgtgcatc
   123421 aggaagctcg atagaggata aaatacgtac gatctacgag gctaagatgg aggtaaatga
   123481 aacaaaagac gaattgttgt ttacatttag gggaaatggc ttcttgtata agatgatacg
   123541 gatcttagta ggaacgcttt tgaaaattgg caatggccga ttgcctgaag atagtatccc
   123601 agatattatt gcgaaaaaag atcgtaatgc agcaggacct acagcacacc ctgaaggact
   123661 ttatttgtat gaagtgaaat atgaataaga ggttatgata gaagtggtca gcttcaagaa
   123721 ataagaaggt atttacgaaa attacttctc aaaattttgc aaaatttcgg cttattttcg
   123781 aagaagctac ttctggaaca ccgtttaaga aagaggtcgt gagcctgtca tttaactctg
   123841 agtcacaaag agcaatttca aaaaacagct tctcatcttt gatgaatatc gtgacttgtg
   123901 gacgaggcgt tgataagtga atcatctttt tgttacctat tttttctgta accaaaaaac
   123961 gatggaacgt tgttttgatt gcccttggtg cggacagtct gaacaggttc catcgtttct
   124021 ttattttcta cgtcttcttc tgtgtgtgtt tcgtggttgt tcttctattg ctggatcaat
   124081 cgtgccataa aaggggcgat tgcggtcaag gtaccagaca taaagaataa acaatgcaat
   124141 acataggaca aaaaggattg cacctatcgt aaatccttca ggcaagtaac tgaaagtgac
   124201 agtatgttta cctgctggaa cttttatcat caagaatgcg tctttgaaat tgctgacctt
   124261 gactggtttc ccatcaattt tagctttcca tcctttgtca taaggaatag ttgtcaccaa
   124321 catggaatct tcagcggtat ttacagtccc agaagctttt ctgccagtgg cttccatttc
   124381 gacacctttt tctttgatct gattcattgc ggcttgatag gctacaacat ctagaccaac
   124441 gactttaggc tccatgaaac ttatttcttt cgtcccataa aaacttgcag taaatgtcac
   124501 tgttgtctct tgaggataat agccaagatc atagtattga ccagaaatgt tgatttgcgt
   124561 ttttcgcgat gtaccattga cagtgatcgt cgcactagaa ctttctaatt gcgcaaaatt
   124621 ggttgggaac aaacttaagt aagcttgtgt atttgcaggc acatggactt cccaagtgag
   124681 ctcttttggc tggttatctg ctgtttctga gtaagtgacg ccagtcgttg tctttgtgat
   124741 cgtcgtattc aactgattct tcaaagtagg tgtatagaat gtaaaatact gttcatttag
   124801 accagacaat gtattgatca agtttgtctg actggtcaaa ttatctgtca ctggctgctc
   124861 aacatcatta acggacaacg gtgcagtaaa tgctagtggc aatgcattga cattctgata
   124921 cagtgtatag tcgccgcttt gaccagcttg gcggaagcca tatttactga acgtgctttc
   124981 gtttttagaa atgttatatt tgattcctgt aaacccatcc atcagcaaag tattattgtt
   125041 ataacggata ttcaaatttg tccctcttga acggaaacct aatttatcca ggtaagagga
   125101 agaattacga tttcttatag aagaaaacaa actgatacca ctgtaaccat agttgatcga
   125161 atcgtttgca gatactggat ccagattttc caagcggtaa aacgagtcgg aatctttttt
   125221 tgtttcattt acaagagctt tcaagtcagg ataaggatca gtatataaac tgcgggaagc
   125281 ataattccaa tcatcaagaa tgccatggat catactgttc gtattgacca gtgcttcagc
   125341 agacatgatc aataataaca atatactcag atgattgaat gaaagttttt tatgctgata
   125401 aaatcccaca gcaaaagcat aaatccctaa gaaaaccact gtcaatacaa aggaagtcat
   125461 cgtcacatag gtgtagcttc cttcaggttt gatgccccat gccaccgcaa agagagcagc
   125521 tacgaccaaa atgattccta acaacagccc acgatcgtct tgttctatct tttcccatcc
   125581 ttttcctgca agcaggagca ctaagaaaga gaacagatag gcataacgga ataaaaacat
   125641 attcggtgca tgcataccat gccagaacaa attcaatgga acaagataaa aacttgcgat
   125701 aagtatggcg aaaagactgc cgtacaaaaa tttatttttc aacggtactt tccgactggc
   125761 aaaataaaac agacagagga ctaatggtag cagacctgcg taaacgaacg gaatcgatcc
   125821 gtattttgtc gtgtcataaa caccaatcat atttttcatg attagatcca gataagaagt
   125881 cgcttctgtt ttcaacgtag tgatctgact cagtgcctcg ccatttgacc gaagatccag
   125941 cactgctggc aatacaatga tcattgaagc gccgcctgcc agtaaagaag tgataccata
   126001 aggaacaatc gtttttttat attctgacca gtttgtcaat agacgggcga taaaatataa
   126061 gaaagaaaat acgccaatca taaaacccat ataaaaactg gataaaaaca agagtaaata
   126121 actgataaat aaaagtttcg gccgtttaag atccataaca cgatgaatcc ccaaaatcac
   126181 taatggaaga taaacaaatg catccagcca catgatgatc tccgaatgtg cagtgataaa
   126241 tgagatcaat gcgtaactga cgctaagtgc aacatgcccc cagcgaggaa tcttgaacgt
   126301 acgtgcaaga aaccaaaaag ccaatccggc acagccgacc ttaagcaaag tcagaacata
   126361 cagtgcatct ggcatcatct ggtttggaaa aaagaacacc agtggcgtga agatcccgcc
   126421 tagatagtaa gaaattaaag ataaataatt caatcctaga gaagcattcc atgtataaaa
   126481 aatactttgc tttccaagaa gaacatttcg gaagctggca tgaaaattag aaaactgtga
   126541 aaaggcatca cttgccaaaa tacttctgct gcttccagga tagattccga tacttagata
   126601 aacaagtgct aaaatcaaaa acggaatcag gaaactagct gctgcgtagc gtccgttttc
   126661 tctaaagaat gactttaaat tttttttcat atttattttc caccaaattt ctatgaagtt
   126721 gtattcagtt tatcatatcc ttgtttttct ctgcttaaaa agagtctagt tttcacaaaa
   126781 aaataaaatt tagaataaat aacttcataa tttgttcgta taacaaaaat aaacgcaaaa
   126841 aaagggtagg aatcaaaagt cccaccctta aaaattttta ttaaataaaa aaccgttcac
   126901 tatctgaacg gtccaagtat cattcaatta aacgcgttca acttttcctg atttcaaagc
   126961 acgagttgac acccaaactt ttttaggttt tccgtcgacc ataacgcgaa ctttttgtaa
   127021 gttaggttta acagtacgtt ttgttgagtt catagcgtgt gaacggttgt ttccactttt
   127081 tgtcttgcga cctgtaaagt aacaaacttt tgccatggta atttcctcct ttgccttgat
   127141 ttggagcaat agaataattc agctcatacc agactaacat atcatataga atgggaattt
   127201 gcaagtacat tttcatagat acaattgaca attgagaaga ataattgtaa attaaacaag
   127261 gttatacctg aaattttgca aggtttttga gtactttggg taactgcctt ttatttcaag
   127321 ttgcgctatg ataaaatatg atagaagaaa aatgggagtt ttttacccgt taaggaggct
   127381 cattcatggc tgtaaaaatt caaacgtcag ctggaaccat tgaaattacc aatgatgtaa
   127441 ttgcaacagt tgttggtggc gccgcgacag atgtgttcgg tgttgtagga atggccagca
   127501 aaaatcaaat taaagataat attactgaga ttttgcgtaa agaaaattac tcaagaggag
   127561 tagttgtccg ccaagaagat aatggtattg ctgtagatgt ttatacgatt atcagctatg
   127621 gtacgaaaat ctctgaagtt tcccgcaacg tccaagaaaa agtgaaatac aatctagagg
   127681 cattattagg cgtaactgcc aattcagtta atgtctttgt acaaggtgtt cgtgtactgc
   127741 cagactaggc aggagactgg ctggtaactc agcagtcgat ctgaaggagg attatctagg
   127801 tgagtgtaac agaaataagt gcaagccagt tccaggaaat ggtccaggca ggtgcgaatc
   127861 gtctgcaagt aaatgcagaa tacgtcaatt cattaaatgt attccctgtg ccagatggcg
   127921 atacgggaac aaatatgaat ctatctatga ctagtggagc taaggcagta gtagattcaa
   127981 cctcagaaaa agtaggagaa ttagcagcaa tgctttcaaa aggattgctg atgggtgcgc
   128041 gcggaaattc cggcgttatt ttgtctcaat tgtttcgtgg attttctaag caaattccag
   128101 atgttgtctc attaaatgct tctgatcttg ctgcagcctt cactcatgga gttgaaactg
   128161 cgtataaagc agtaatgaaa ccagtagaag gaacgatttt gacagtagct agagaagcag
   128221 cgaaagctgg agaaaagaaa gcaaaaagta ctgatgatgt cgttgaagta atgacagctg
   128281 ttgtaaaagg agcaaagcgt gctttagcta aaactccaga cttgcttcca gtcctaaaag
   128341 aagtcggtgt cgtagacagt ggagggcaag gactgctgtt tgtttatgag ggctttttaa
   128401 gtgcattgaa tggagaattc caagcggatg aaacatatga accttctcca gcagaaatgg
   128461 atgatatggt caatgcagaa catcatcgca gtgtccaagg tcaaatggcg acagaagata
   128521 tccattttgg ttactgtaca gaaatcatgg taaaaatcgg agaaggacct acagtcgata
   128581 gtacattcga ttacgaagaa ttccgtaact atttagatgg tataggagat tctttacttg
   128641 tggtcaatga tgacgagatc atcaaagtcc acgtgcatac agaaaaccca ggagaagtct
   128701 tgaattatgg acaaaaattc ggttcattag tcaaaatcaa agtcgacaac atgcgcttgc
   128761 agcatgagac gattttggaa cacgatgaag aagtgaacga gtttgcgaaa aaagaaatac
   128821 cacgtatccc gtatggtatc gtagcgatcg ctgctggtaa aggcgtccaa gagctgtttg
   128881 aaagtttagg cgctaattat gttatcagtg gtggacaaac aatgaatcca agtacggaag
   128941 acattgttaa agcgattcaa gaagtaaacg cagataaagt gattgtcttg ccaaacaata
   129001 agaacatctt catggcagct gatcaagcag cagaagtagc agatatccca gtagcagttg
   129061 ttccttcaag aacgatttcc caaggattga cagctatgct ttcattcaat gatcaagctt
   129121 ctttagaaga aaacaaagaa acgatgacag aaatgttgtc tagcgttgtg agcggtcaag
   129181 tcactcacgc gatcagagat acctcaattg acggtgtaga gatcaaagaa ggagactttt
   129241 tgggcatgat cgatggaaaa atcctgatct ctaacccaga tatcacagca acagcgttaa
   129301 gtacactaga acaaatgatc aatgaggaca cagagatcgt aacgatcttg gcaggtgatg
   129361 aaggaacagt tgaacaagca aatgaatttg ctgagaaact aacagaaaaa catcctgatt
   129421 tggaaatcga gatccaccaa ggagatcagc ctgtctatcc ttatctattt tctgctgaat
   129481 aatttctgtg tcagaatatc tttctaacac agtattcatt cataaaaggc cttcggttag
   129541 tgatcaggta tgatcgctga ccaagtcctt tttttgttaa aggagggagg aaaaatttat
   129601 gcgttcttta gatgatccaa tcactatgct ggcaggagtc ggagaaaaaa gagcagctag
   129661 tcttgccagc ttgggcatcc aaacgattga agacttactg acttattatc cttttcgcta
   129721 cgaagatatt caggaaagaa atctaaacga gatccaggat caagaaaagg ttactttgaa
   129781 aggaatcgta gtctcgcctc ctgtgatgaa tcgatttggt tataaaaaaa gccgattgca
   129841 atttcgtatg atgcaagaac atgatgtgtt caacgtttct ttttttaatc aaccttatct
   129901 aaaagaaaaa gtcattttat cggaggaaat cgccgtatac ggtaaatggg atgcaaagcg
   129961 taaagccttg aacgggatga agattttagg ttctcaaaca atggatgact tttcgccgat
   130021 atatcacgtc aacaaatcaa ttcgtcaaac gacattagtt gatctaatca aaaaagggtt
   130081 tcaagaatac ggcacattga ttgaagaaaa tctgccaaac aaccttgtgg agaaatatcg
   130141 actgcttgac cgagcttctg ctgtaagaag tatgcatttt ccaaaagacc acgaagaaaa
   130201 ccatcaagcc aaacgacgtg tcgtttttga agagttcttt ttatttcaaa tgcgtcttca
   130261 aggattgaaa aaagcagaaa aagcagaaac gaatggtttg gagatccttt atgatgtcca
   130321 aaaattgaaa caatttactc aaaagctacc ttttgaactg acaaatgcac aaaaacgtgt
   130381 aacgaatgaa atctgtcggg atcttcgcag tccgcagcat atgcagcgac ttttgcaggg
   130441 agatgtaggt agcggaaaaa cagtggttgc cgcgattgcg ttatacgcta ccgttacagc
   130501 aggtttccaa ggtgcgttga tggtgcctac agaaatcttg gcacaacaac atatggaaag
   130561 cttgcaacag ctgtttgatc ccaatgaagt aaccatcgca ttgattacgg ggtcaacgaa
   130621 agcaaaagaa cgacgtgagc tccttgaaaa actagagcaa ggggaaatta acgtcgtgat
   130681 cggcacacat gcattgatcc aagatggagt cgaatttcag aatttaggtc tagttattac
   130741 ggatgagcag caccgttttg gcgtgaacca gcggaaagta cttcgtgaaa aaggctggcg
   130801 accagatgtc ttatttatga cagcgactcc gattcctaga acattagcta ttacagcata
   130861 tggtgagatg gatgtatcta tcattgatga acttccagct ggacgtatcc cgatcgaaac
   130921 acgctgggta agaacacctc aattggacag tgtactggat tggacgaaaa aagaactggc
   130981 aagaggacat caaatgtatg tcatctgtcc gctgattgaa gaatcagaag cattagatgt
   131041 aaaaaatgca gtggaaatct atgaaaaact tcgtgaacta tttgcaccaa aatatgaagt
   131101 tggcttgtta catggtaaaa tgaagaatca ggaaaaagaa gtaatcatgg aagccttcaa
   131161 agacaaccag atgcagatat tagtttcgac tactgtaatt gaagtagggg taaacgtgcc
   131221 gaacgcgacc gtcatgctga tcatggatgc ggatcgattt ggattggcac agctgcacca
   131281 acttcgtgga cgtgttggac gcggaagtga tgcttcctac tgtatcttag ttgctaatcc
   131341 taaaaatgaa ctaggtgtgg aacggatgaa aatcatgaca gagaccacca atggttttgt
   131401 actaagcgaa aaagatctgg aattacgtgg tcctggtgaa gtatttggct tccgtcaatc
   131461 tggtctgcct caatttgcga ttgctgactt ggtgacggat ggaaatgttt tggaggtagc
   131521 cagagaagag gctgcagccc tttggcaaat aaaggattgg cagatgcttc ctgagtatca
   131581 gcctttagcg caaagcctcc aaatagaaaa tcaggataat cgttatttcg attagcagac
   131641 tgtgctatac tttatactga tgacggaaaa aggagtggaa acaatgaaaa ttgccgtaga
   131701 tgcaatgggc ggagatcacg cacctcaagc aattgtagaa ggcgtggctt tagcgcagca
   131761 agattttcca gaagtagaat tcttacttta cggaaaagaa gcagaaatca agaaatactt
   131821 aacaaatgaa aaaaacatca cgattatcca tacagacgaa aaaatcaata gtgatgatga
   131881 gccagtaaaa gcaattcgac gaaaaaagac tgcatcaatg gtccttgctg cacaagcagt
   131941 gaaaaacggt gaagcagatg ctgtattttc agcagggaat acaggcgcgc tactagcagc
   132001 agggttgttc atcgtaggac gtatcaaaaa tatcgaacgc cctggcttga tgtctacctt
   132061 gccagtagta gggaaagaag gtgccggttt cgatatgctg gatcttggcg ctaacgcaga
   132121 aaacaaacca gaacatttgt tgcaatacgg tattttaggt tctttttatg cacgtaaagt
   132181 ccgaggtatc ggacgtcctc gtgtcgcact cttaaacaac ggaacagaag caacaaaagg
   132241 tagtgaagtg acgaaaaaag cctatgaact ccttcagaat gaaacaagct tgaattttat
   132301 tggaaacgta gaagctcgtg agctactcaa tggtgtggct gatgtagtgg tcacagatgg
   132361 atttacaggc aacgctgttt tgaaatctat tgaaggaaca gcaatgaata tgatgaatct
   132421 attaaaatct gctattctaa atgaagggat caaaggaaaa atgggcgcta tgcttttaaa
   132481 agacggctta cgttctttga aagcagaaat ggattattcc aaacatggcg gtgccgtttt
   132541 gtttggcttg aaagcaccag tcattaaaac tcatggagca acaggccccg atgctgttcg
   132601 ctatacgatc cgccaaatcc acacaatgct tgagacagat gtagttggac aattagtcga
   132661 acaatttgaa aaaagcgaag aatagtattt ggatatctga agcgatccgt tccattgaaa
   132721 aaaaggtgga cattcctgaa aaatgccagt aaaattagcc atggtgtagg taattgacaa
   132781 gtgtatgatt cttggaggtg aaaaagttga ctcgcgaaga agtatttaac aaagtagcga
   132841 aaattatttc aaatcatttt gagatagata ccgataaagt gacggatgaa ttgaacatca
   132901 aagatgattt aaaagctgat tcaattagta ttatggaatt cgttttagag cttgaagatg
   132961 aattcggtac ggaaatttca gatgaagacg ctgaacaaat tgaaacagtc ggtggcgcag
   133021 tagattatat cagcagccat cttaaataat ttcaaataaa agcaaagaag gataaaaagc
   133081 tgcatgcagc tttttatcct tcttttttta atctttttga cacgtaaaag tcatttttct
   133141 gataattctg gcgataaaca gaaattatgt tgcaaagtaa agcggttttc tatataatta
   133201 ttaataattc attacacaaa gataagaata acctttgtta taaaacgatt tattctgtgt
   133261 aatgtccttt tttattaaga aaaacttcca tttaggaagc agagaggggt attcgattgt
   133321 ccgataacca attattagaa gttcagaacc tacatacagg attccgactc aaagatgact
   133381 attacgatgc agtagatgac gtttcattta ctttagacaa aaacgagatt ttagcaatcg
   133441 ttggggaatc tgggtgcggg aaaagtacct tggctactac gattatggga ttacttgatc
   133501 ctaataacac aaaaattaca ggtgagattt tatataacga tctgaattta atcgacctga
   133561 acgaaacgct ctataataaa atccgcggaa atgatatcgg aatgattttc caagatccgt
   133621 tgtctgcatt aaatcctctc atgagaatcg aagaccagat caaagaagga ctttcctatc
   133681 acacaaagat gaatgcagaa cagcgtcaag ctcgtgcact agaattgcta gaacaagtag
   133741 ggattcctaa tcctgcgaga gttggacgcc aatatcccca tgaactatca ggcggtatga
   133801 gacaacgtgt catcatcgca atcgcaatcg cctgcaaacc tccaatcgtc attgcagatg
   133861 aaccgacgac agccctagat gtaaccatcc aagcacagat tcttgattta ctgaaagacc
   133921 ttcaggaaga aacaaaaaca gggatcatct tgatcactca tgacttagga gtcgtagcag
   133981 aaatggctga tcgagtggca gtgatgtatg gcggacagtt cgttgaagta gcaggtgtaa
   134041 aagaactgtt tgatcatcct aagcatcctt atacacgctc tttactgaac tctataccac
   134101 aagaaggaaa tcatgatgca gaactccatg tgatcgaagg tgtcgttcct tctctgaaaa
   134161 acatgcctcg taaaggttgt cggtttgcac cacgtattcc atggatacca gcaagcgatc
   134221 atgaagaaga gcctatcctt catgaagtcg caccgaacca cttggtacgt tgctcctgct
   134281 ataagcattt ccactttaga gacgaaaaag gagaggtgta gatgacagaa ttaatcacaa
   134341 tcaaagacct gaaagttcat taccctattc gcagtggatt cttcaatcga gtaacggatc
   134401 atgtatatgc tgtagatggt gtggatttta ttatcgaaaa aggaaagaca tatggtttag
   134461 tgggagagtc tggctctgga aaatctacta cgggaaaagc cgttgtggga ttagaaaagg
   134521 taacagccgg acaaatcatg tatgaaggaa aagatgtaac gaagcgaagc aaccgcaaaa
   134581 aaatgggtta taacaaggat gtgcagatga tcttccaaga ttcaatgtcc agtttgaatc
   134641 ctaaaaagcg agtgttggat atcattgctg aacccatccg aaattttgaa cggttaagcg
   134701 atcaagaaga aaagaaaaag gtaaaaggac tgctagatat cgttgggatg ccggaagatg
   134761 cgctatataa atatcctcat gaattttcag gcggacaacg tcaacgtcta ggagtagccc
   134821 gtgctgttgc taccaatcca aaactgatcg tagccgatga acctgtatct gctctggatc
   134881 tatctgttca agcgcaagta ttgaatttca tgaaacgaat ccagcaagaa tacggcctca
   134941 gctatttatt catttcacat gatttaggtg tagtaaaaca catgtgcgac aatatcgcaa
   135001 ttatgtacaa aggtcgattt gtagaaatcg gtacaagaga agacatttat aatgacccgc
   135061 gacatatcta tacgaaacgt ctgctttcag ctattccgca aatcgatgta gaaaataggg
   135121 aaagccacaa agaaaatcga cgaagagtag aacaagagta tatccaaaac caaaaagaat
   135181 actatgatgc gactggtcga gtctacgatt tgcgtacgat cacaactaca cacaaagtgg
   135241 cgttgaaaga tggaggtgca agctaatgtg gaaaacgatt ctgcgacgtg ttttattgat
   135301 gatcccgcaa gttattattt taagtgttct gatcttctta ttagcccaag cgatgccggg
   135361 ggatccattt accggtttga tcaatccaaa tcaggatccg gcagtgatcg aacagatgcg
   135421 acaagcagct ggcttgaatg acccatggta tgtccagtac ttccgttgga tcggaaatgc
   135481 tttgcaaggc gattttggtc aaagtttctt atacaaacgc tctgttgctg acttgatcgg
   135541 cgaacggatc atcaacactt tatatctatc gatcttgaca gttgtcctta cttatttgat
   135601 tgctgtgcct ctggggatgc ttgctggccg gtatcaaaat tcaatcttgg ataagattgt
   135661 cgtaatctac aacttcttta gttttgctgt tcctttattt atcttcggct tgatcatgct
   135721 atttgttttt ggttatcgtt taggctggtt cccaacaagt ggatcacaaa cactaggttt
   135781 gcaaggtgga tttatcactc aatggataga ccgtttgaaa tatattctgt taccatcaat
   135841 tacccaagca tttttggcga ctgccgtcac aatccaatat ctgcgaagtg aagtaatcga
   135901 ttcgaaatcg ctcgattttg tcagaacagc ccgttccaaa ggggtaccga cgaataaagt
   135961 attcagtcga catattttcc gaaatgcagc gttgccgatg gcttctcaaa tggggtatga
   136021 aatcacttcg ttgattgctg gttctgtagt tatcgaaaag atttttggtt atccgggagt
   136081 cggaaaacta tttattgatt ccatcggcca acgggactat accgtgatca catccttagt
   136141 attgatttta ggaatcgcga cgctagtggg gacattactt tcagatatca tcatgagtat
   136201 cgttgacccg cgtattcgga ttcaataaaa ccaatcagaa aggagaatgg atcgatgagt
   136261 gaaaaaaaca atacagcagt tcaagaaagt attcctccta tggggatacg aatgattgct
   136321 cgagaattta aaaaagataa aattgctatt ttttcattag gtttgctagt ggttttatta
   136381 ttagtgatct ttatcggtgc gatgctgacc gatcaagaca aagtgatgta tgttagtatc
   136441 ttcgacaaat acgctgcacc aggaacagtt tcgacacaag gacaaaagtt cattctggga
   136501 gcagatgaag gcggacgtga tgtattagga caattgatca taggtgctag aaactctgtt
   136561 acgatcggat ttgcgatcac gatccttact tcgatcatcg gggttggatt agggatcatc
   136621 tctggctact acggagggat cattgacaac atcttgatgc ggatcgttga ttttatcatg
   136681 attctaccga tcatgctgat cattatcgtc ttcgtatcga ttatttccag atacaatgtc
   136741 tggtccttta tattcatcat gagtgcattt tattgggtag ctaaagcccg attattccga
   136801 agcaagacat tatctgaagc aagaagagat tatgtcagtg cctcaaaaac aatgggaacc
   136861 aatgatttta aaatcatgtt ccgcgaaatc atgccgaatc taagttcatt aatcattact
   136921 aatttgacga tgaactttgc ggcaaacatc ggtatcgaga caactttgac tttcttaggt
   136981 ttcggcttgc cggcaaatgt acctagttta ggtacattga tcggttatgc aagtaacgga
   137041 gaagtcttag tgaatcggca atggatctgg ttacccgcat caatccttat tttagttttg
   137101 atgttgagta tcaattatgt tggacaagca ttcaagcgtt ctgcagatgc gcgccaacgg
   137161 ttaggctagt atagaagcga agggggaaat aggaatgaag aaaacgattt ttggatttgc
   137221 agcgctgatg tctgctgtcg ttcttgcagc atgcgggggc ggaggtacag atacctctgg
   137281 aaacaactct ggaggcaacg gcaataacaa agaggaatta acttttccaa ttgcaacaaa
   137341 aaataatgat gatgcaatcg aagacggcga attagaagct gcggtcgcaa cggacagtca
   137401 gtttaaagga ttgttccagt gggagtttta ccaagattca tatgatgcag cttttatggc
   137461 tccttctcat gaaccgctat ttgcaaacga tgacgatttc agaatcacag acgacggagc
   137521 tgcaacgctt gatctagatg aagatacgaa aaaagcgaca atcaaagtaa aagacaacgt
   137581 caaatggtca gatggtgaag atgtaacggc ggacgatgtg attttccctt acgaaatcat
   137641 tgggaataaa gattacactg gtatccgtta tgacgacact ttccgtaaca tcgtaggtat
   137701 ggaagaatat catgatggaa gtgccgacac aatctccgga atcaaaaaaa tagacgacaa
   137761 aacagttgaa atcgaatata aagaagtaaa cccaagcatg cttcaatcgg gtggtggtat
   137821 ctggtcatat gcagcaccaa aacatacgtt agaaggtgta gcaatcaaag atatggaatc
   137881 aagcgatcaa gtacgtaaaa atccagtgac ttttggccct tattacatga gtaatatcgt
   137941 tgcaggagaa tcagtagaat acttgccaaa cgagcactac tggaatggta cgcctaaatt
   138001 gaaaaagatc acgatgaaat ctgtaccgat ggcaagtgca actgaagcat tgaactctaa
   138061 attatatgat atgattttcc aaatgccaac agatacttac gatacctata aagaaattgc
   138121 tggctataca aacttaggcc gtgaacaaac ttcttatact tatctaggat tcaagttagg
   138181 taaatggaat gcagatacaa agagtgtgga atacaatcca gattcaaaaa tggctgataa
   138241 atcattacgt caagcaatgg gctatgcatt agataataat gcagtaggtg aacgtttcta
   138301 tgcaggtttg agaagcaatg cgacttcatt gattcctcca gtattccagt cataccatga
   138361 tgatgagatg aaaggattca cacaagatct agacaaagcg aaaaaactat tagatgatgc
   138421 tggctacaaa gatgtggatg acgatggttt aagagaagac aaagatggaa ataaactaac
   138481 aatcaacttt gcttcgatgt ccggtgggga aacagcgcaa ccattggcag attactatat
   138541 ccaacaatgg aaagaaattg gtttggatgt ccaatacaca acaggtcgtc tgatcgaatt
   138601 caattctttc tatgataaat tagaaaacga tgatcctgaa attgatgttt accaagctgc
   138661 ttggaataca ggaactgatc caaatccaag tggactatgg ggaccaaatg ctgcgttcaa
   138721 ctacactcgt tatgaatcag aagaaaatac aaaattgatc aacgatatca gttcaagcaa
   138781 agcatttgat gaagagtacc aaaaagaagc atatcaaaaa tggcaacaat atgcatttga
   138841 agaagcattt gcgattccaa cgttgttccg taatgaagta ttgccagtca acgaccgtgt
   138901 caaagactgg gattggtctt atgatgtacc aaacccatgg gcaaatgttt ctgttacagc
   138961 agattcacgt tcataatcac taaaaatgac cgaaaaaggg cgatgtcctt tttcggtttt
   139021 ttgatatttt tctgtttatt tctctaatat tcaggtcaag gcgctgattt catgacttct
   139081 ccaataaacg gtgttcaaag tccagtttct cggtattaag tcaaatttat gcaaaaatat
   139141 ggaaagccat tttcacaaaa ttttttcttc atactcgaaa ctaaacgaat ttttcacaac
   139201 ttctcgtcaa tcactaggat tattaaagct ttacttacct tttgaccgaa ccatttcaaa
   139261 tttgacaaaa aaccagtata ataaggaagt atcgaaaaaa tatccataaa aggaatgtgg
   139321 aaaatggaca accagctgac aaaagaacta aaagaaaact ataacatcgt ttttcacgat
   139381 ctaaatttgc ttgaacaagc ttttacccat tcatcctatg tgaatgagca tcgcaatctg
   139441 caattatcgg ataatgagcg acttgaattt ttaggagatg ccgttttaga actgatggtt
   139501 tctcagtatt tattccgttt atatcctcat ttgccagaag gaaaattgac aaaaacacga
   139561 gctgcgatcg ttcgcgaaga cagcttgtcg aaatttgcca aagaatgtca ctttgatcaa
   139621 tatgttttgt tgggcaaggg agaagagaat tcaggaggac gtacgcgacc agcattgctt
   139681 tgcgacctat tcgaagcttt tttaggcgcg ttatatcttg accagggatt cgacacgacc
   139741 catgcattca tcgaaaaagt gatttttcct aaagtcaaag caggtgcttt ttcacatgag
   139801 atggatcata aaacaaaact acaagaagtc ttgcaaaaat caggtgatgt atcaatcgaa
   139861 taccgattga tcaatgaaga aggtccagct catgaacgag tattttggat cgaagtttat
   139921 gtagatgatc aattgattgg cactggacaa gggaaatcga aaaaattagc agaacaagct
   139981 gcggcggaaa atgcattggc agcactgtaa aagtaagtga gggaaagctt tgtatttgaa
   140041 acgaattgaa atagccggtt ttaaatcatt tgcagacaag acagtcattg attttgaaaa
   140101 tagcgtcaca gcagtggttg gaccaaatgg cagcggaaaa agcaatatta cagaggctat
   140161 ccgctgggta ttaggagaac aatctgctaa aagtctgcga ggcggaaaaa tgccggatat
   140221 catctttgcc ggttccgata cccgtaagca gctgaatatt gcagaagtca cagtgatttt
   140281 agacaatagt gatcattatc tgccattgga gtacaatgag atcagtgtaa cccgccgtta
   140341 tcgacggact ggggaaagcg agtttttcat caataaacaa agctgcagat taaaagatat
   140401 ccaagaattg ttcttagatt ctggattagg aaaagaatcg ttctcaatca tttctcaagg
   140461 aaaagtagaa gcgattttca gtagtaaacc ggaagaccgt cgtgggatct ttgaagaagc
   140521 agctggtgtc ttgaaataca agcagcggaa aaagaaagca gaacagaagc tttttgaaac
   140581 agaagacaac ctcagccgcg tccaagacat catccacgaa ttggaagaac agttaactcc
   140641 tttggccgcc cagagtgagg cagcaaagga gtttttacgg ctaaaagaaa cactgactca
   140701 aaccgatgtc tctttgatgg ttgctgaaat caagacagca aaaaaagatt gggacaacaa
   140761 acaagcacag cttgcgaaat tcaatctaga attaggcaaa ctatctgagt cgatccaaga
   140821 acaagaatcc attttggcga agcagcgtaa agaaaatgcg caagccgatc gtctgatcga
   140881 aaaaaatcag caagtattat tagatctttc ggaaaaactg aagcagacag aaggacaaaa
   140941 agatgttttg caggagcgga caaagcatac acaaaaaagc tcgcaagaat atcaaacttc
   141001 attagcagaa gcacaaaaaa aggttaaaca ttttgaaaag cttcaagaaa gcttgatgaa
   141061 agcagcagca gaaaaagaaa cagagatcca aaaagctgaa gcaaatctca taaaaacaca
   141121 gcaagaatta gaaaaatacc aaaaatcaac gaaagaatta ttggcagaat taagagatca
   141181 atatgttgat ttgatgcaag aacaagcagc tgtaggaaac gaactgaagt atctagaacg
   141241 tcaatatata caagaaacag caaaaagcaa gcagacgtta gccaagcaat cggaagtaga
   141301 agcatcagta gaccgattga tcttacaaaa agaagaattg acacaaaagc aggcgcagct
   141361 aaaatcatct ttaactgaaa caaaagagaa gttagaaatg atccaacaaa acgggaaaaa
   141421 gttccaagaa gcattagcaa aagaacagcc taaaatgtat caattaatga atcaagtcca
   141481 gcagctacgt gctcgtaaga aaagccttca agaaatccaa gaaaactatt ttggttttta
   141541 ccaaggggtt cgattggtct tgcagcataa acagcagctt tcgggtattg tcggagcagt
   141601 ggctgaactg atcgatgttc ctgcagattt cacgttagct atcgaaacag ctttaggtgg
   141661 ggcagcccag catgtcatcg ttgaaaatga aaaagatgct cggcaagcca tcacgtattt
   141721 gaaacagcaa agaggaggaa gagcaacatt ccttccactg acgacaatca aaccaagaca
   141781 attaccggct catatattga cacaagcagc agctgtagaa gggtttatag ggattgccag
   141841 tgaacaagtc agttatcccg atcaaatcca aactgtggtt caaaacctgc taggaacgat
   141901 ccttttagcc aaagacttaa ctagtgccaa tgcaatcgcg caaacgatcc gctatcaata
   141961 tcgagtggtt tccttagaag gtgatgtgat gaatgccgga ggatccatga caggtggagc
   142021 gaataaacga ggaaaccaag gcagtttgtt tgtacaaaat caagaattga aacagttgac
   142081 tagtgaattt gaagaagcag ataaacaact ccaagcacaa gaaaaaaaag ttcaggagct
   142141 gcaacaagaa acagctcgtt tagccgaaga acaagaagtt ttgcgtacac gaggcgaaca
   142201 attacgtttt gaagaacaag aagcgacaaa tcagctacaa aacatcataa atgaacttga
   142261 acgttttgaa aaagaaaagc aaatctcaac ttttgagaca cgtgaactgc agcagtttat
   142321 cgaagattac gaaaagcaaa cgaacgaatt gaaagacaaa caaacagatc ttgaatcgca
   142381 acgacaaaaa atcgacgaag aaatcaaatc gttaagtcaa gaaagcgacc agatggaagc
   142441 cagaagagca caagtacaaa gtcaaaaagc acaagaacaa gcagatcttg ctgtcttgaa
   142501 agagcagttt aatcatctgc agatccagct ccgcggtgcc cgagtccaaa aagcagaggc
   142561 aaccgaacgt caagaagcga tagaaaagca gttggcgaca ttgacagcag acttttctga
   142621 tcatgaagtc acagaagaaa gtttggaaaa acaaattaac gaattatctg ctcagcgaga
   142681 aacattaaaa gccgagttgg caaaagccaa agagcagcga gatagaaggc aaaaggagat
   142741 cgataagctt gaagcagtct tggcagagcg taatcgtgag caaaaagcac gactgtcgga
   142801 acaatccaaa ttagaagtcc aaaaagaccg agctgaaatg attttagata atcatttgac
   142861 ctatctgcag tcagaatatc agctgacatt tgagaaagct tcccaagact atcaagaaac
   142921 aaccgatatc gaagacagta gaacaaaggt ttcatcctta aaagaacaga ttgaaaaact
   142981 gggaccagta aacttaaatt caatcgaaca atacgaacaa gtcagtgaaa gacatacatt
   143041 cttagcaaca cagcgagatg atctgttagc agcgaaaaac caattgtttg aaacgatgga
   143101 tgagatggat gatgaagtgc ggacaagatt caaagaagta tttgaagcta tccgtcaaga
   143161 attcaaaatt gtctttccaa atatgtttgg cggcggtaaa gctgaattag tactgacgga
   143221 accaactgat ttgctgaaaa caggtattga gattgaagta caacctcctg gcaaaaaact
   143281 gcaaagtcta agtttgcttt ctggaggaga acgagcactt acagccatcg cgttgctctt
   143341 ttccattatc cgtgtctgtc ctgttccgtt ttgtatctta gatgaggtag aagcagcgtt
   143401 agatgaagcc aacgtgaaac gttttggtcg ttacttgagc gatttccaag atgacacaca
   143461 atttatcgta gtcacacacc gcaaaggaac gatggtcgca gcagatgtac tgtacggagt
   143521 gacgatgcag gaatccggtg tatcaaaaat cgtttctgta cggatggaag atatcaatga
   143581 agaggcgaaa atcaacgaaa cgaaagtgta ggaacgaaaa tgatcaaatt agtagcaatc
   143641 gatttggacg gtacattatt aaatgaacaa aagctgattt cagatgagaa taaacaagca
   143701 ttagcacaag caaaacagca aggggtcaag atcgttctat gtacaggacg ccccttagct
   143761 gcgatggcgc attatctgca agaattagga ctggtagatg aaggtgacta cagcatcact
   143821 ttcaacggcg gtttggtaca aaaaaatgat actggtgaaa tcatggaaaa gaaagtgatg
   143881 gaagtatcag atatccaacg cttatacaaa ctggctcagc aattggatct gccactagat
   143941 gttttgtctg acaatgtggt tttacagctg cctagtgccc caaggaagca atccttgtac
   144001 aatgtgttga ataagctgct gcaattccaa ccagcggata taagcgatat tacagatgaa
   144061 tttgtgctta ataaggcagt aatcgcttat gaccaagaag aattagatcc taaaatcaaa
   144121 gaaataccag cagaattcca tgaaatgtat gagatcatca aaacaagaag tatgcttttg
   144181 gaatttatgc caaaaggtgt tacaaaagct tatggtattt ctttattggc aaaagatctt
   144241 ggtttgaaac aagaagaaat catggcgatc ggtgatgagg aaaatgattt accgatgatc
   144301 caatatgctg gactaggcgt agcgatggag aatgctgtgc ctttcgtcaa agaagcagca
   144361 gatttcgtga cagccagcaa tgaagaaaat ggcgtagcca aagtgatcca aaaatttgta
   144421 ttagagtagg gggagtcaaa tgggattttt tgataaaatc aagcgtgctt ttactggcga
   144481 agagaaaaca gaagaagttg aagtacagga gaagtacgac aagggtttag aaaagacgcg
   144541 taaaacattt ggtgaacgga tgaatgagtt gtttgccaat tttcgaacag tcgatgaaga
   144601 cttttttgaa gaattagaag aaacacttat cggtgcagat gtaggttttg aaacagcgat
   144661 acgaattacc gaagcattac gtcaagaagt gaaactcaga aatgcgaaaa aatcggcaga
   144721 agtccaaaat gcgatcatcg agaaacttgt ggatctctat gaagcggaag gaatcaatga
   144781 agtaaatgaa ctaaatatcc aagaagacgg actaacagtt attttgtttg tcggtgttaa
   144841 tggtgtaggg aaaacaacaa gtattggtaa acttgcccat cagttcaaaa acgaaggtaa
   144901 aaaagtattg atggcagcag cagatacctt ccgcgctgga gcaatcgacc agttagttgt
   144961 ctggggcgaa cgcgctggtg ttgaagttgt tcgtggcaat gcaggaggcg atccagcagc
   145021 tgtcgtattc gatgctttgg aaagagcaaa gacagagcag gcagatgttt tactagttga
   145081 tactgcaggc cgactgcaaa ataaagtgaa cttgatgaac gaattagaaa aaataaaacg
   145141 agtaatccag cgggaattac cagaagcacc ccaagaaaca cttcttgtat tagatgcaac
   145201 cactggtcaa aacgcgatgg ttcaagcaaa acaattcaaa gaaacaacag atgtgaccgg
   145261 tcttgttttg acaaaattag atggtacagc aaagggcggt atcgtacttg ctatccgtaa
   145321 tgaattgcat ttaccagtga aattggtcgg tcttggtgaa ggaatcgatg acttggagcc
   145381 gtttgatcca aatgattttg tcgttggatt gttcaaagga ttactaaaag aagaataacc
   145441 catgtctaaa aagcaggagc tgtgacaaaa gttgcagctc cttgtttgaa tgattgtttt
   145501 taacatagct gtgtttttga tgccttcatt tttatactta tttgtaagcg gttctcaaac
   145561 aatttcgttc tttttcttag actttttgat tataattaga ttcatatgaa ttggaggtca
   145621 cttaatgatg aattttaagc aattattatt gcatgtcaat gcgcgccctt ttatcgacca
   145681 agctcgattt ggtatagaac gggaaggaca gcgggttgat cttgcaggaa atctagcaaa
   145741 aaccgatcat ccagcaatct ttggcgatcg atcctatcac ccctatatcc aaacagattt
   145801 tagcgaaaca caaacagaga tgatcacccc tgttaccgat tctattcccg aattatttca
   145861 gtatctcgct gctgtttatg atgtgactgc tcgttctata ccgaaagaag agatgatctg
   145921 gccattaagt atgccacctg ccttaccgga aaaagacgaa gagatcatta ttgcaaaatt
   145981 aaaaaatttc gaagatgtct tgtatcgacg ttatttagca aaagaatacg ggaagcgaaa
   146041 acagatggta agcggtattc atttcaattt tgaatttggc gatgagttgc taagaacatt
   146101 gttcagccat caggaagaat ttcaagattt ttccgaattc aaaacagaac tttatttgaa
   146161 aacagcgaga aactttatgc gctatcgctg gatgatcact tatttattcg gtgcttcacc
   146221 aatgagtgag aagaactact ttttagatga atcacatccg caagaacctg ttcgcagtat
   146281 tcgcaacagt gcgctgggct atacgaatca tccaaatgtg aaagtttcct atgcttctat
   146341 gaaacagtat ttagcagata tcgagcgaat gatcgaagaa gggaaacttt cggaggagaa
   146401 agaattttat acaccgcttc gtttccgagg cggaaagaaa gtcgcagatt tagcaacaac
   146461 aggtgttcgt tatattgaat tgcggaatat cgatttgaat ccttatgcaa gattgggtat
   146521 caatccagag caagttcggt tcttacaatt attcctgatg tacatgttat ggacagaaga
   146581 aaaagaagac tgtgaccaat gggtagcaga aggtacgact cgaaataaca aagtagcact
   146641 agaacaacca tcagatcaaa cagaatttca tcaagaaggt agagaaattc ttgaaggaat
   146701 gaagcaaatg ctggttgaat tggattggtt ggattctctt tatttagtag aggaagcatt
   146761 gactcaaatg gatcatcctg aacaaacgtt agcagcgaaa ctctatcaag aagcacagct
   146821 atcgagtcag caagaagttg ctgtggcatt gggacatcaa tattataaag aaagccatga
   146881 acgtccctat cagttggccg gttttcgcga aatggaactt tctactcaga tatttatgtt
   146941 cgatgccatc caaaaaggtg tccaagtcaa agtattagat gagtcggatc aatttttgcg
   147001 tctgcaattc caagaccatg tagaatatgt gaaaaatgca aacatgacaa gtaaggacag
   147061 ctatatcgtc ccacttatca tggaaaacaa aacagtaacg aaaaaagtct taaaagaagc
   147121 tgggttccgg gtaccaggag gcgcagaatt ttcatccatg gaagaagcgg taaaagctta
   147181 tccgagattt gccgagcagg catttgtgat caaacctaaa tcaaccaatt acgggttagg
   147241 tatcacgatt ttcaaggaag gagctagtct ggaagattat caagcaggtt tagccattgc
   147301 ttttcgtgaa gacagttcgg ttttagtaga agaatttatg ccgggaacgg aatatcgttt
   147361 ctttgtgatc gacggagaag tccaagccat catgttgcga gtccctgcta atgttattgg
   147421 tgacagtatc cgaacagtga aagaacttgt tgaagaaaaa aatagtgacc ctttgcgtgg
   147481 aacgaatcat cgtgcacctt tagaattgat ccaattaggt gaattagaac aattgatgtt
   147541 gaaagaacaa gggttgacga tcgaatcagt tccccaagcc aatcaaattg tttatctaag
   147601 ggagaactca aatatcagta caggtggtga ttcgatcgat atgactgatg aattttctga
   147661 agcttacaaa aaaatcgccg tttctgcggt agaagcacta ggagctaaga ttagtggtat
   147721 cgatttgatt ataccagata aagaaatcga tcctacaact gataaaaaag catatgggat
   147781 catcgaagca aatttcaatc cagccatgca tatgcatgtt tatccttttg caggaaaagg
   147841 cagaagattg acgatgaatg tattgaaatt gttatatcct gaagtatttt aaaagaaaaa
   147901 gcttttgaca gattgtccta tttgatgtca atctgatcaa aagctttttt tgcatgtaaa
   147961 aatttatgtg ttttttcgtt ttaaaataaa cgatcccaga agcttttttt cttttttggt
   148021 ttttcttttt cagctggcga agagttttct tctgggtatt ttttttcgat atcaatcaca
   148081 ggttcattta ctgcttcttt tgctgttaag agcaatccga attcctcagg atttgcagtg
   148141 acgtaatcgt tgactacagt gaaacggcta ttgcttttcg ttgctagctg gatatattgg
   148201 ttttggacag aaaggggtag agccccattc aagagtatgg aagcatctgg atgttttttg
   148261 agttctttta aaaagttttc tttgtttttt ggttggatca tttcagcaac agtcatacta
   148321 agatagcagc gttccctgaa tgtccctaaa tatttatgct gttcttcagg gttcactaaa
   148381 ggtgtaccat aaagtccctt atccaaatgg ctttttacat catcttgtgc cataaaaaat
   148441 accctccttc ttctctttgt ctttcttacg attatagcat attcccaata atacctaaaa
   148501 catatgaaaa agcggttgct tttgttcaac gattcactta aaataagaat gaaaatcatt
   148561 ctcaattaga aaggtggatt ggatgcgcta cggacgacta gtagcattat tagttatttt
   148621 aagtagtatt tcattgttca tcggagtatc gaatgtacaa ttgtcagaac tgctccagtt
   148681 agatgggcaa agcttacaaa tcttgctagt gactcgtttg ccacgaacga tttgtttgat
   148741 ccttgtggga gcgaccagta gtatttgtgg gttgatcatg caacatttga cccaaaataa
   148801 atttgtttca ccaacgactg cgggcacgat ggatagtgcg cgtttaggta ttttagtggc
   148861 tatgattttc ctacctggtg catccttgat tgtccgatcc ttgacagcat tttgctttgc
   148921 ttttgcagga acattgcttt ttttatccct tacgcgattg ttcctccaga aaaatcaatt
   148981 gatgcttccg ttgattggag tcatgttagg gaatatcatt ggttcagttg ctactttttt
   149041 tgcttatcaa ttccagttgg tacaaaatat gacttcatgg cttcaaggga attttgcgac
   149101 tgtgatacga ggaaattatg agttattgta tgctgttgtt ccattgttgc tcttggtttg
   149161 gctatttgct taccgattta cgatcattgg tctgggcgaa tcgtttgcag taaatctggg
   149221 aatagattac cagaagatgc agtttttagg cattggctta gtatcattgg ctagtgcagt
   149281 catgttgatc atggtaggaa gcattccttt tatcggagtg atcattccga atcttgtctc
   149341 tagaatatat ggagatcaag tgcacaaaac aattggcgta actgctttag caggtagttt
   149401 gttcttagta ttttgcgatc ttgtcgctcg cgtgttgatt tttccttatg aaataccagt
   149461 cagtgtgatc gttggaatca tcggtggggc tatcttcctt tatcttctga taaggggacg
   149521 acgatatgct taaaaaaaag ccatctattt ttattggtat gcttgttctt gttttatttg
   149581 ttacaggaat gtacttgacg atccatacat atggaaactg gcattttgca tgtgcattga
   149641 ggagtaagaa aatttttgca tttatccttg tctcgctagc tgtcagcagt gccacaatca
   149701 gctttcagac aattacgcat aaccagtttt tgactccttc agtattggga cttgagtcgt
   149761 tatatgtcct tgtccaaacg gtccttttct tctttatcgg aggagtgacg atgcttcagc
   149821 agacaggtac agtttttttc ttattgaacg ttgggctgat ggtcgggctg agtctattgt
   149881 tatttttctt tcttttgaaa aaaatgagag cgaatctttt tttattactg atgtcaggga
   149941 tgattttagg tacgcttttt ggtagtgtca gtaccttttt acaagtcatc atggatccga
   150001 atgaatatga tttgcttcaa ggcagattat ttgcaagctt tggcaatatc cagagtcagt
   150061 atcttttgcc tgcttctttg atcattatcg gctgctggta cctgttattt cgatatcgac
   150121 atgtgctaga cgttttccat ctcggaaatg aacaagcagt aaacctcggg atagacacag
   150181 atcgttttga atttttgatt ttatgttgtg tcagtctttt gacagggaca tcaacggctc
   150241 ttgtgggtcc agttactttt ttagggttta ttgtcgcaaa tatcagttat cgtgtctttt
   150301 ctacttatcg tcatggtcag ctatttatcg gaagctttct ggtagctatg ctgtttctga
   150361 caggaggaca gctcgcagta gagcagattt tcggctggaa tacaacagtg agtgtcgtcg
   150421 ttgaatttgt cggaggaatt tattttgtca caaaattgat tcgcgaaagg aagagtatcc
   150481 tatgattgat ttacaaaagg tcaataaact gtaccatgga aaatcagtgg ttaaagatgt
   150541 acagttaacg attcctgaaa agaaattgac tgcttttatc ggtccaaatg gtgctggaaa
   150601 gtcaacggtg ttgtcgatga tcagtcgttt gataccaaaa gatacaggtg aaatctattt
   150661 agaccataac gaagtaaagg cttggaaatc caatgaatta gccaaaaaat tatcgatcct
   150721 acgacaatcg aatgaaataa atgtccaaat caccgtgaaa gaattagtag aatttggacg
   150781 atttccttat acgaaaggaa aattgacgac aaaagacgag gaaatcgttc aggaatcact
   150841 ggaacacctt gggttagaag aaatagcgga tcaatcgatt gacactcttt caggcggtca
   150901 actccaacgt gcgtatattg caatggtgct agcgcaagac acggattata ttttactgga
   150961 tgaacctttg aacaatctag atatgaattt tgcggttcaa atcatgcaga ttttaaaaaa
   151021 tttagtacaa gaaatcggga aaacaattgt tattgttctt catgatatca actttgctgc
   151081 aagttatgca gacgaaattg ttgcaatgaa agatggacag ttatttacgc aaggaacgac
   151141 ccaagaaatg ataaaaaaag atgtattgga tgaattatac gaaatggaca tacggatttg
   151201 tgagattgaa ggccgcagat tctgtcttta tttctaaaac taacattagg agagaagaga
   151261 tgaaaaaatt agtagtaggt atcttgattc tagcatcatt tggtttagca gcatgtggaa
   151321 atagcaacaa caccagtcag gcagacacaa aaaaaagcag cacacaaact gaaactacat
   151381 tgacgataac agatagtaat ggagaccaaa tcgaggtgcc aaataatcca gaaaaagtcg
   151441 tcgtattcga caatggttct ttagatacga tggatgctct tggtgttgga gataaggtag
   151501 ttggagcagc tacaagcagc cttcctgagt atctttcatc ctataaaaaa gtagaatcag
   151561 caggtggaat aaaagaacca gacttagaaa aaattaatca gcttcagcca gatctaatca
   151621 tcatttctgg ccgacaaaga gattttcaaa aagatctaag tcaaattgct ccgaccattt
   151681 tcctttcttt agatgcgaaa aatccatggg aatctttcca gcaaaatgtc actgctttag
   151741 gggagatctt tggtaagcaa gaagaagcta aaactcaatt agaggaatta tctagtgcaa
   151801 tcgatcagac gaaaaagaaa gcagaagcta ctgacaaaaa agcactagtc acacttgtga
   151861 atgaagggca attatcagcc tacggatctg gttctagatt cggtttcatc catgatttat
   151921 ttggctttga acaagcagat gatcaaatcg aagcatccac tcacggtcaa agtgtttctt
   151981 atgaatatgt gctggaaaaa aatccggata tcttatttgt agtagacaga acaaaagcta
   152041 ttggtggaga cgacagcaaa gatgatattt ctgccaatga actggtagca caaacgaatg
   152101 ctggtaaaaa tcagcagatc atctcccttg aaccagatgt ctggtattta agcgggggcg
   152161 gtttagaatc aatgaaactg atgatcgaag atgtgaatca agcatttaaa tagcataaat
   152221 aacagaggat taaactctca tactatgtaa caataatgtt tcttacattc ttaaatagca
   152281 agagcctatc ctcaaagaag ttatcaaaaa ccatccgtaa aatcgtattg atgattttac
   152341 ggatggtttt tatttatttg agaaatcttt tttcaacgtg aattcattat ctacatcata
   152401 cgggttgatt ctagaatggg gagtggcaaa aaatagtgtg atccattttt tcagcatcaa
   152461 gatcgcctcc tttgatttga atcaaaggta caaagcgaaa cttagataaa acttaaattt
   152521 agatattttt attttgtacc gatctcttct ttaaacgatg ttccatctgc tgcttctcgg
   152581 caataagtcc actagactag aaaatatgag aagctatttt ctgtccagcg ttcttattac
   152641 tcaaagcaaa tcgcagttgt cacaatctct tctaaacgat gttccatctg ctgcttctcg
   152701 gcaataagcc cactagacta gaaaatatga gaagctattt tctgtccagc gttcttatta
   152761 ctcaaagcaa atcgcagttg tcacaatctc ttctaaacaa tgttcaatca gctgaccttc
   152821 ggtattagct caaagcactg atttcacaac ctctatttag gcatgtgtct cagcaagcgg
   152881 ttgatagttg atgatctgca tttttcgata aaaatcggcg ggaagcttac tccaccgttt
   152941 taataattga tagaaataac tctcttctgc tttgatttta tactcgctta atatcaatcc
   153001 aaaactattc gttttttttg aagctaattt tttataaata tccaatgctt tggttttatc
   153061 ttcattgaca aagagtgttt ttacttcaat ataagaaccc tcgatatttt gtgtttcttc
   153121 gataaaatag atgtttttta tatattcctt catagtgatt cctccaaaga agtcttttat
   153181 ttgataagtt tactctaccg aagagttgtt aataatccgt gaacaaaaag taattctttt
   153241 tccaatagtt gttaaaggtt ttttattttt tatagtattt tttgttattt aagaaaggaa
   153301 taaggttaaa caaataacag gttgcttttt gggtcttttt ccgttcaaga aactgaacga
   153361 agaaaaggga aagttgtctc ttttgtgata agagaaatca taataaacga atgacttact
   153421 ttccaataaa ttgagaacag tcagaaccag acaaattagt tgcatctgat gaataaagtg
   153481 attattctat gacatgaggt gatacagatg aaattagaag tgacaaaaga agcacaagaa
   153541 gtattgaaga ataaattaga agcagacgat caacttttat tagatatcga aaacggtgac
   153601 ggtccatttg cagaaagcca agtcagttgc caattggata cggcatttcg attgatcatt
   153661 gtcaaaaaag atacacaaac agatctaagt ctttattctg tagtggctga tacaccagtt
   153721 ggaccaatca aaatcaaaga cagtgcaata ctttacatgg atgatccatc cacacttgct
   153781 ttagaaccaa cttataatag tttacaatta aaaggaccaa gcggcttgag aaaaggcaac
   153841 ttgcaagttg ttcgaaaaga ctagagggat aaaatgggaa aattggcgat catcagcgac
   153901 ctacatgtgg acatcaataa attcggcgaa tcagagctga tgcagctttg gcaagttttg
   153961 caaaagcaca agatcactcg gcttcatcta gccggagata cggctaataa agtagaccgt
   154021 tgcctagctg ttgtcgaatt tttcgtcaat aaaggattat ctacgacatt tcatttcggc
   154081 aatcacgagt tggcagatgt gcccaatgaa cagatgatgg accattttcc agacccacat
   154141 tttttaaatg aacggtatat tgctttaaat gagcagaccg ttcttttagg gatgaatggc
   154201 tggtacgact atcagttttc cgaattgaaa gattacgagg caatcgtacg aatgaagcgt
   154261 ttgtattggt atgatcggtt catccagcgt gggaaaacag atctcgaggt caatgcagaa
   154321 atgcttgcag ctgcaaaaaa tttgctagac cagctggaag caaaaaaact tgaggtgatt
   154381 ttatccactc atttcgttcc taaacgggca tttatcatgt atcaatctgc tccttatgag
   154441 cgttggaaca aattaaatgc atttttagga tcagaatcat tcggagaatt acttgaccgt
   154501 tattcaaata tcaaacaagt agtttttggc catacgcatc gtcgctttga agataaatcc
   154561 atcggtcaca cgatttacag ctgcagacct tttggttatt attatgaatg gcagctgacc
   154621 cgagattttg tcttgaaaga acagttgcta gacagctatg atcctatgaa attacgtgtc
   154681 ctcttgcgtg cccatcaccc agcttttcag gcctatcaaa cacaacattt gcaagaggaa
   154741 tttgaacaag cgatgacaat cgttccgtat tgagacagca ttagtaatgt gtaaaagaaa
   154801 ataccttgta aaacataagg ataagtaaga gcagtagatc catttatcgt ggatatgctg
   154861 ctttttttgc ggaaaataat cagcgaatgt ttatttgatc ggatgatttg taactcgcag
   154921 agtactagat gcaagcgtgt attctttttt tgaacgataa tcacaaaaaa aatataatat
   154981 acatttttta tttaattata attaatattg attgaagtct aggcagtcaa gtcacatttt
   155041 gatagatagg agggggactt acgaattatt ttaaaggcta tgacagctgt atttctagat
   155101 tgtgtttgca tcaagttgca ataaaaacta gaaatcaaat cgggctgata atcatttata
   155161 actaatcgat acataggacc aaatataggt ctatgttctt ttatttcata agtatcgtaa
   155221 aacagaattt tgctatggat taatccaatc gactgatatg tttagtaaat aaagaaagag
   155281 gaatgtcaat gatgaaaaaa gaaatcgtat taacagcagc aatgatgtta ttcagcatgg
   155341 tagcaagtac gacttttgtt tctgcaactg aagtataccc aaaggaatat aacacagaag
   155401 gaacgattac atttgaagca ggagatgagg gtgtaactcc tcctgttgat ccagagaatc
   155461 ctgatcccaa taaacctgtc gatccatcag atcctccaag ccctggaaca ggaggggcat
   155521 tatcgattga ttatggatca aaattcaaat ttgggactca aaaaatttct actgcggata
   155581 aaacgtatta tgcagctgct gatgtgatga acgatgggtc tagaaaaccg acatatgtcc
   155641 aagtgacaga taggagaagt accttatctg ggtggaaatt aagtgtctct caaccagaac
   155701 agtttaaaac tgccagtggg gatgaactag ttggagcaca gctgaaattt acgaaagggc
   155761 aggctgtttc tttggttgat ccaacatata cgccgcaaac ggtgaattct gaattaacgt
   155821 tgacaccggg aggaaacaat acgttagcaa ttaatgctaa atcaggaaca ggtgtgggga
   155881 cttgggtcta tcgatttggt gcaaatgaaa atgaaaatca agatgcggta cagctttcgg
   155941 tacccggtaa atctgtcaag ttagcgcaac aatattccac taaattagtt tggacattag
   156001 aagatacacc taacaactag tttactgaaa agaactgtta aaaataaata cgtagtcata
   156061 ttgtcttgcg aggtaatcga gcaaaaattg tcaaaggcta ggctaaattt gtttggatac
   156121 gaatagttca tctaggaatt taacgatcag gaggaaaaga tatattgaaa aagaggagga
   156181 tcgtgctcat tttaagcagt ctcttagtga ctaatatctt tccgatcata gggtactctt
   156241 tggaattgaa tcagttggag catggaaata gaagagacga agaaagcaaa ctcacttcga
   156301 cattcgacag tttaatagaa tccaaccaga cacaagaaag cagtgaggat ttaagtattt
   156361 cgagtagtgg agagaccact gacaacgtag aagctgaggg ttcggacaaa caaggactag
   156421 aagatgcacc aatttctgcg gttgagctgc ctgacgatcc caatattatt tctatcgata
   156481 aaatttttca aacacctatc ggtactagca cgtccatatt ggaaaatggg aagttactgc
   156541 agttgaaccc agcagaaagg tctcaaagag gagctatttg gtcaaataag aagattagtt
   156601 tactctcgga ttttacattt aaatcttatt tatacttagg aaatcaacga gatagagcgg
   156661 gagatggcat gacctttaca ttgactggcg atcctagaat ggctagtaat cccagtcaag
   156721 ttattggatc gccaggtatg ggaattggct catattctac tcgttctggc caaccttaca
   156781 ttgcgaatgc gctctcgatt gagtttgata cgtataaaaa tagtggttct tctgatcgaa
   156841 tggatcgaga gataactgct gataatagag ggcatggaca tgtcgctttt gtcacgccta
   156901 aaccaaataa taataattat tctggagagc atactggcgt gacggtagct cctacatttc
   156961 tttctaatgg cacatggcgc ttgttaataa ttaaatggga cgcggagcaa agaagtctta
   157021 cttatgattt ggaaggtgtc ggtcgctctt ctcggattat acctgatctc attaggcagt
   157081 ttggttctac agaagtaaat tgggggttta cttcttcaac aggtactttt tttcaagaaa
   157141 atgctgtcgc tgtcacgcga cttccatcga atgtcacatc aacagctgat gtaaaagtca
   157201 acgatagtga ttatggggcc atcgctgaag ctggaggaaa cgataagata actatcagaa
   157261 atacattgaa ggtcgagggg gattttcttg aatataagaa aatgcagact agtatcgacc
   157321 tcccacaaga attaactatt cccgagcata tcttgatcaa tggaaatcaa attgatgcca
   157381 aagatatctt gataaccgga aatcgagtca cgctaaatct gacagattat tttattgctg
   157441 gagatacgtt aataatcgaa ttggagacaa ctttgcagga agtaattcct gaaaaagtac
   157501 tcactatgca ttttgaatac cttgaaaacg ggaatttgat tgagcaatcg aatgaaataa
   157561 acctaaagat cgcaaagctg aaggagatag atatccatgt ttattataaa gataaagaca
   157621 gtcagattga tattgctgaa atgaaaacaa tcactgggaa aataggagag aagtataaag
   157681 aaactcctat tgatattgaa gggtatgttt ttgactcgga ttcagcgaat acagaaggca
   157741 tcttctccga aaatacagag gatatctatt tttattacag aaaaggcaaa ctttatctct
   157801 caactgctcc tcaatatgtc aattttggaa aacataaaat atccagtaga ccattaagtg
   157861 aattcggaca gttttcaggt gggttgaaaa ttatagatga acgggctttt ggaagttgga
   157921 aattacaatt gaaacaagag aaagttctta caaatggaga ttttgagctt ccagaagctc
   157981 tttcctttgt tacctctgaa aatacaacgg ttatagggac atccgctgtt acgattttcg
   158041 aaagtgatca aaagggtgaa agcgatttgt cctctctttt agattctaca gctcatcgtg
   158101 gaatcagaat agatattcct gtagaaaacc aaagaatcgg aacctttgag gggaaactat
   158161 cttggatact tgcagatgtc ccaggaaatt aacaggaaga gaagaatata acaaaattat
   158221 tgagtttcaa gaagggcaca ggtaccatag gctcttgtgt cccacagaga caagattttg
   158281 ttatagtctt ctcttacata tgattaaagg agcgattttc ttgagaccaa aacaacaatt
   158341 atttataaca ctcctagtta ttttaggggc actttttaac aatatatcag tgtcagctag
   158401 tgcatttaat ttttcagtga cgccgataac ttcagagaat caaatcgaca agagaaaaac
   158461 ttacttcgat cttcaacttg atccggatca ggaagtagaa gtaaaagcgg aattgagaaa
   158521 tgatacagaa aaagaagtga aaatcgatat ttctgtgaat agcgcaacca ccaattcaaa
   158581 tgtgatggtt gaatacggaa aaaacgagat tgaaaaagac atgagcctga tctttgatct
   158641 ggtagattat gtgagctatc cacagatagt gacgctaaaa cctaaaagtg tccaaaccgt
   158701 tgcttttcat gtcaggatgc cgaatgagcg atttgatggt gtattggctg gtgggatcac
   158761 attccaagaa atccagacgg aaaaggacca aacagaaact aaggatcaaa gcttatcgat
   158821 tgagaatgaa tacacctata ttattgcttt gttgatgcaa cagacactga acgaagttgc
   158881 tccgaacctt actcttcatg aagttaaacc agatcaaatc aatgcaagaa atgtcatctt
   158941 agcaaacgtt caaaatgatc aaaaaaccta tatcaatcaa gtagttattg aaacaaaaat
   159001 tacaaaaaaa ggacattctg aagttttata tcaagaggaa aaagaaggat tgcagattgc
   159061 gccgaataca aatttttctt ttccaactgc tttaaatggt caaccgctaa ccccaggtga
   159121 atatcacctt acaatgactg ttttaggaaa tgaaaatgaa aatggaaaat tttcgagaaa
   159181 aaaaggaaat actacgatca actataccaa tcaatgggta tttgaaaaag attttacaat
   159241 agacggaaaa gtagccaagg aattgaacac gacggatgtt acgattaaaa aagacaataa
   159301 ttggatttat atcttagtag cttcactttt cttattgttt attttattat gcatactttt
   159361 gtttgttttg agaaaaaaag aagagaaaga aaagtaaggt taagataaca aatagtaaat
   159421 ttttattatt gtaggatggt tgggctcttt ttataacaat ataaaatata ccattttatt
   159481 aataaaaatg catactagta aatgatataa ttctaataac aggtttgatc gcgagaaagg
   159541 ccaaataaaa cgctctccaa aatgttaaaa aaaagacagg acgatgtata ttatacaaac
   159601 aagaatcgct gacaacagtg actcggatcc aggaaatcag ttttatcccc agctagttgg
   159661 tgaatgcatg gaaagtaata tacgtagaaa gagctgatga ctaatgaatt atgagttttt
   159721 tttaagcaaa gaagatcaca gaagttattc attacttaaa tatttagaag caagctcaaa
   159781 tttatcagag tcaatatcga atgttcaaga agagttgtcg ctatcgacat ttctcttgaa
   159841 aaaaacgatc gataagctga aacatgattt acaaaagttc gatctagaga aaaatttgcg
   159901 agtaaccgtc agtgaattgg atatatgtct ggaaattaat ggaaaatgtt ctagcaaagc
   159961 tctgttatct cgttatataa cggattcttt atctatgaaa atggtattgg ctttctttca
   160021 ggaaaaatat atctcagtag aaaattttgc taaacagcat cacgtgagtt attctgtggc
   160081 ttataaagta ttacaaagac taaaaagaaa tctaaaaaaa tatcaaattt tttttgaaaa
   160141 gagaaagttg
//
LOCUS       DARPZJ010000002       102862 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.002, whole genome shotgun sequence.
ACCESSION   DARPZJ010000002 DARPZJ010000000
VERSION     DARPZJ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 102862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.002"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..1235)
                     /locus_tag="SLE23_000161"
     CDS             complement(<1..1235)
                     /locus_tag="SLE23_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEI8467099.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQK"
     gene            complement(1228..2820)
                     /locus_tag="SLE23_000162"
     CDS             complement(1228..2820)
                     /locus_tag="SLE23_000162"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEI8467100.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(3329..4054)
                     /locus_tag="SLE23_000163"
     CDS             complement(3329..4054)
                     /locus_tag="SLE23_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467101.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(4208..4534)
                     /locus_tag="SLE23_000164"
     CDS             complement(4208..4534)
                     /locus_tag="SLE23_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467102.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(4571..4936)
                     /locus_tag="SLE23_000165"
     CDS             complement(4571..4936)
                     /locus_tag="SLE23_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEI8467103.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(4973..5188)
                     /locus_tag="SLE23_000166"
     CDS             complement(4973..5188)
                     /locus_tag="SLE23_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467104.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            5317..5652
                     /locus_tag="SLE23_000167"
     CDS             5317..5652
                     /locus_tag="SLE23_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467105.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(5728..7725)
                     /locus_tag="SLE23_000168"
     CDS             complement(5728..7725)
                     /locus_tag="SLE23_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467106.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(7823..8098)
                     /locus_tag="SLE23_000169"
     CDS             complement(7823..8098)
                     /locus_tag="SLE23_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467107.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            8330..9064
                     /locus_tag="SLE23_000170"
     CDS             8330..9064
                     /locus_tag="SLE23_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467108.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            9103..10245
                     /locus_tag="SLE23_000171"
     CDS             9103..10245
                     /locus_tag="SLE23_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8467109.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(10340..11731)
                     /gene="sufB"
                     /locus_tag="SLE23_000172"
     CDS             complement(10340..11731)
                     /gene="sufB"
                     /locus_tag="SLE23_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEI8467110.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(11736..12206)
                     /locus_tag="SLE23_000173"
     CDS             complement(11736..12206)
                     /locus_tag="SLE23_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEI8467111.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(12193..13428)
                     /locus_tag="SLE23_000174"
     CDS             complement(12193..13428)
                     /locus_tag="SLE23_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEI8467112.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(13425..14711)
                     /gene="sufD"
                     /locus_tag="SLE23_000175"
     CDS             complement(13425..14711)
                     /gene="sufD"
                     /locus_tag="SLE23_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEI8467113.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(14724..15497)
                     /gene="sufC"
                     /locus_tag="SLE23_000176"
     CDS             complement(14724..15497)
                     /gene="sufC"
                     /locus_tag="SLE23_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEI8467114.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(15694..16542)
                     /locus_tag="SLE23_000177"
     CDS             complement(15694..16542)
                     /locus_tag="SLE23_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEI8467115.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(16566..17252)
                     /locus_tag="SLE23_000178"
     CDS             complement(16566..17252)
                     /locus_tag="SLE23_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467116.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(17245..18279)
                     /locus_tag="SLE23_000179"
     CDS             complement(17245..18279)
                     /locus_tag="SLE23_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8467117.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(18342..18598)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18674..19012)
                     /locus_tag="SLE23_000180"
     CDS             complement(18674..19012)
                     /locus_tag="SLE23_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEI8467118.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(19014..19370)
                     /locus_tag="SLE23_000181"
     CDS             complement(19014..19370)
                     /locus_tag="SLE23_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEI8467119.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(19376..20563)
                     /locus_tag="SLE23_000182"
     CDS             complement(19376..20563)
                     /locus_tag="SLE23_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEI8467120.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(20754..21599)
                     /locus_tag="SLE23_000183"
     CDS             complement(20754..21599)
                     /locus_tag="SLE23_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8467121.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            21833..22798
                     /locus_tag="SLE23_000184"
     CDS             21833..22798
                     /locus_tag="SLE23_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEI8467122.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            23175..24218
                     /locus_tag="SLE23_000185"
     CDS             23175..24218
                     /locus_tag="SLE23_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HEI8467123.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(24280..24744)
                     /locus_tag="SLE23_000186"
     CDS             complement(24280..24744)
                     /locus_tag="SLE23_000186"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEI8467124.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            24990..25937
                     /locus_tag="SLE23_000187"
     CDS             24990..25937
                     /locus_tag="SLE23_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8467125.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(26148..28220)
                     /locus_tag="SLE23_000188"
     CDS             complement(26148..28220)
                     /locus_tag="SLE23_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEI8467126.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(28153..28530)
                     /locus_tag="SLE23_000189"
     CDS             complement(28153..28530)
                     /locus_tag="SLE23_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEI8467127.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(28659..29237)
                     /locus_tag="SLE23_000190"
     CDS             complement(28659..29237)
                     /locus_tag="SLE23_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8467128.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            29369..30661
                     /locus_tag="SLE23_000191"
     CDS             29369..30661
                     /locus_tag="SLE23_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEI8467129.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(30721..31839)
                     /locus_tag="SLE23_000192"
     CDS             complement(30721..31839)
                     /locus_tag="SLE23_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEI8467130.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(31853..33274)
                     /gene="arcD"
                     /locus_tag="SLE23_000193"
     CDS             complement(31853..33274)
                     /gene="arcD"
                     /locus_tag="SLE23_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HEI8467131.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(33520..34641)
                     /gene="mnmA"
                     /locus_tag="SLE23_000194"
     CDS             complement(33520..34641)
                     /gene="mnmA"
                     /locus_tag="SLE23_000194"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEI8467132.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            35045..35644
                     /locus_tag="SLE23_000195"
     CDS             35045..35644
                     /locus_tag="SLE23_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEI8467133.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(35782..37068)
                     /gene="efmA"
                     /locus_tag="SLE23_000196"
     CDS             complement(35782..37068)
                     /gene="efmA"
                     /locus_tag="SLE23_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HEI8467134.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(37339..37683)
                     /locus_tag="SLE23_000197"
     CDS             complement(37339..37683)
                     /locus_tag="SLE23_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEI8467135.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(37820..38965)
                     /locus_tag="SLE23_000198"
     CDS             complement(37820..38965)
                     /locus_tag="SLE23_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEI8467136.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(39145..40119)
                     /locus_tag="SLE23_000199"
     CDS             complement(39145..40119)
                     /locus_tag="SLE23_000199"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEI8467137.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(40199..41074)
                     /locus_tag="SLE23_000200"
     CDS             complement(40199..41074)
                     /locus_tag="SLE23_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HEI8467138.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            41204..43111
                     /locus_tag="SLE23_000201"
     CDS             41204..43111
                     /locus_tag="SLE23_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HEI8467139.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(43652..46930)
                     /locus_tag="SLE23_000202"
     CDS             complement(43652..46930)
                     /locus_tag="SLE23_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HEI8467140.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(47201..47746)
                     /locus_tag="SLE23_000203"
     CDS             complement(47201..47746)
                     /locus_tag="SLE23_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8467141.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(47758..48450)
                     /locus_tag="SLE23_000204"
     CDS             complement(47758..48450)
                     /locus_tag="SLE23_000204"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEI8467142.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(48469..48753)
                     /locus_tag="SLE23_000205"
     CDS             complement(48469..48753)
                     /locus_tag="SLE23_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467143.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(48766..49329)
                     /locus_tag="SLE23_000206"
     CDS             complement(48766..49329)
                     /locus_tag="SLE23_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEI8467144.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            49557..50219
                     /locus_tag="SLE23_000207"
     CDS             49557..50219
                     /locus_tag="SLE23_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HEI8467145.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            50343..51539
                     /locus_tag="SLE23_000208"
     CDS             50343..51539
                     /locus_tag="SLE23_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEI8467146.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(51640..53016)
                     /locus_tag="SLE23_000209"
     CDS             complement(51640..53016)
                     /locus_tag="SLE23_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467147.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(53053..53919)
                     /locus_tag="SLE23_000210"
     CDS             complement(53053..53919)
                     /locus_tag="SLE23_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HEI8467148.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(54008..55033)
                     /locus_tag="SLE23_000211"
     CDS             complement(54008..55033)
                     /locus_tag="SLE23_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8467149.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(55051..55725)
                     /locus_tag="SLE23_000212"
     CDS             complement(55051..55725)
                     /locus_tag="SLE23_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8467150.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(55909..56802)
                     /locus_tag="SLE23_000213"
     CDS             complement(55909..56802)
                     /locus_tag="SLE23_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8467151.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(56876..58573)
                     /locus_tag="SLE23_000214"
     CDS             complement(56876..58573)
                     /locus_tag="SLE23_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8467152.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(58566..59879)
                     /locus_tag="SLE23_000215"
     CDS             complement(58566..59879)
                     /locus_tag="SLE23_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEI8467153.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(59879..63397)
                     /locus_tag="SLE23_000216"
     CDS             complement(59879..63397)
                     /locus_tag="SLE23_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEI8467154.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(63690..64148)
                     /locus_tag="SLE23_000217"
     CDS             complement(63690..64148)
                     /locus_tag="SLE23_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8467155.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(64446..64964)
                     /locus_tag="SLE23_000218"
     CDS             complement(64446..64964)
                     /locus_tag="SLE23_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEI8467156.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(64966..65583)
                     /locus_tag="SLE23_000219"
     CDS             complement(64966..65583)
                     /locus_tag="SLE23_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEI8467157.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(65580..66434)
                     /locus_tag="SLE23_000220"
     CDS             complement(65580..66434)
                     /locus_tag="SLE23_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8467158.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(66431..67342)
                     /locus_tag="SLE23_000221"
     CDS             complement(66431..67342)
                     /locus_tag="SLE23_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8467159.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(67383..68717)
                     /locus_tag="SLE23_000222"
     CDS             complement(67383..68717)
                     /locus_tag="SLE23_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8467160.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            68925..69755
                     /locus_tag="SLE23_000223"
     CDS             68925..69755
                     /locus_tag="SLE23_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HEI8467161.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(69999..70317)
                     /locus_tag="SLE23_000224"
                     /pseudo
     CDS             complement(69999..70317)
                     /locus_tag="SLE23_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(70439..70633)
                     /locus_tag="SLE23_000225"
     CDS             complement(70439..70633)
                     /locus_tag="SLE23_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467162.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(71138..71323)
                     /locus_tag="SLE23_000226"
     CDS             complement(71138..71323)
                     /locus_tag="SLE23_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467163.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(72173..72514)
                     /locus_tag="SLE23_000227"
     CDS             complement(72173..72514)
                     /locus_tag="SLE23_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEI8467164.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(72514..72744)
                     /locus_tag="SLE23_000228"
     CDS             complement(72514..72744)
                     /locus_tag="SLE23_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8467165.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            73030..73368
                     /locus_tag="SLE23_000229"
     CDS             73030..73368
                     /locus_tag="SLE23_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467166.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(73573..73812)
                     /locus_tag="SLE23_000230"
     CDS             complement(73573..73812)
                     /locus_tag="SLE23_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEI8467167.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(73788..74135)
                     /locus_tag="SLE23_000231"
     CDS             complement(73788..74135)
                     /locus_tag="SLE23_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEI8467168.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(74867..75448)
                     /locus_tag="SLE23_000232"
     CDS             complement(74867..75448)
                     /locus_tag="SLE23_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8467169.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(75631..76257)
                     /locus_tag="SLE23_000233"
     CDS             complement(75631..76257)
                     /locus_tag="SLE23_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8467170.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(76279..77610)
                     /locus_tag="SLE23_000234"
     CDS             complement(76279..77610)
                     /locus_tag="SLE23_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEI8467171.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(77765..78166)
                     /locus_tag="SLE23_000235"
     CDS             complement(77765..78166)
                     /locus_tag="SLE23_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEI8467172.1"
                     /translation="MKKAYETAMINHGGRNGEVEEPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVFEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(78252..78458)
                     /locus_tag="SLE23_000236"
     CDS             complement(78252..78458)
                     /locus_tag="SLE23_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467173.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(78553..80055)
                     /locus_tag="SLE23_000237"
     CDS             complement(78553..80055)
                     /locus_tag="SLE23_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HEI8467174.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(80073..80528)
                     /gene="argR"
                     /locus_tag="SLE23_000238"
     CDS             complement(80073..80528)
                     /gene="argR"
                     /locus_tag="SLE23_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEI8467175.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(80626..81243)
                     /locus_tag="SLE23_000239"
     CDS             complement(80626..81243)
                     /locus_tag="SLE23_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HEI8467176.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            81464..82837
                     /locus_tag="SLE23_000240"
     CDS             81464..82837
                     /locus_tag="SLE23_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8467177.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            82912..84024
                     /locus_tag="SLE23_000241"
     CDS             82912..84024
                     /locus_tag="SLE23_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEI8467178.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(84096..85733)
                     /locus_tag="SLE23_000242"
     CDS             complement(84096..85733)
                     /locus_tag="SLE23_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HEI8467179.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(85901..86509)
                     /locus_tag="SLE23_000243"
     CDS             complement(85901..86509)
                     /locus_tag="SLE23_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8467180.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(86894..88045)
                     /gene="queG"
                     /locus_tag="SLE23_000244"
     CDS             complement(86894..88045)
                     /gene="queG"
                     /locus_tag="SLE23_000244"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEI8467181.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(88064..88816)
                     /locus_tag="SLE23_000245"
     CDS             complement(88064..88816)
                     /locus_tag="SLE23_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467182.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(88957..89907)
                     /locus_tag="SLE23_000246"
     CDS             complement(88957..89907)
                     /locus_tag="SLE23_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEI8467183.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(89908..90747)
                     /locus_tag="SLE23_000247"
     CDS             complement(89908..90747)
                     /locus_tag="SLE23_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEI8467184.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(90744..91490)
                     /locus_tag="SLE23_000248"
     CDS             complement(90744..91490)
                     /locus_tag="SLE23_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEI8467185.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            91728..93098
                     /locus_tag="SLE23_000249"
     CDS             91728..93098
                     /locus_tag="SLE23_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467186.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(93153..94049)
                     /locus_tag="SLE23_000250"
     CDS             complement(93153..94049)
                     /locus_tag="SLE23_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8467187.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(94163..94333)
                     /locus_tag="SLE23_000251"
     CDS             complement(94163..94333)
                     /locus_tag="SLE23_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467188.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(94330..95007)
                     /locus_tag="SLE23_000252"
     CDS             complement(94330..95007)
                     /locus_tag="SLE23_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEI8467189.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(95098..96003)
                     /locus_tag="SLE23_000253"
     CDS             complement(95098..96003)
                     /locus_tag="SLE23_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEI8467190.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            96178..97632
                     /locus_tag="SLE23_000254"
     CDS             96178..97632
                     /locus_tag="SLE23_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8467191.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            97648..98679
                     /locus_tag="SLE23_000255"
     CDS             97648..98679
                     /locus_tag="SLE23_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEI8467192.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            98686..99873
                     /locus_tag="SLE23_000256"
     CDS             98686..99873
                     /locus_tag="SLE23_000256"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEI8467193.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            100029..101411
                     /locus_tag="SLE23_000257"
     CDS             100029..101411
                     /locus_tag="SLE23_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEI8467194.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            101383..101769
                     /locus_tag="SLE23_000258"
     CDS             101383..101769
                     /locus_tag="SLE23_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467195.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(101969..102637)
                     /locus_tag="SLE23_000259"
     CDS             complement(101969..102637)
                     /locus_tag="SLE23_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEI8467196.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        29497 a        21461 c        18163 g        33741 t
ORIGIN      
        1 atcttttgta agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
       61 gcgatcgtgt cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc
      121 ctagtaaaag gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt
      181 ccttcagtgt tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg
      241 aactcattat ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc
      301 gtcataccaa gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg
      361 aattcatttg gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca
      421 tcaaactgtt ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag
      481 tctaaatctt tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt
      541 tcccaatctt ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg
      601 aacatttttt gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga
      661 agagcgatag tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat
      721 attggaaatt gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct
      781 gaacctggat tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata
      841 aaatattctg aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat
      901 acacccggtt ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc
      961 atgataaaat cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta
     1021 attttatatc ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa
     1081 ttgctattag atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact
     1141 ccatcttttt tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct
     1201 gggaaacgaa tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg
     1261 taaccacgct tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt
     1321 ttctagcact tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc
     1381 aattggttct tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt
     1441 ttctttgatt tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc
     1501 ataggtttcg aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt
     1561 gacaaattct cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa
     1621 tacaatcacc gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac
     1681 agcataaata ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg
     1741 gaataaaact ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa
     1801 accatgaaga agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt
     1861 aaaccgagaa tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt
     1921 cattactact gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc
     1981 cccattgcgg agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc
     2041 tagattgtat gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt
     2101 taagtagtta cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact
     2161 aaagaatcgt cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat
     2221 atgaggcgtg taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag
     2281 aaattcataa gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa
     2341 tttcttaatg acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt
     2401 tgattggaga tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg
     2461 cacaaaggct ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa
     2521 gacgttgaaa agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat
     2581 cagatcttct tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct
     2641 taccgtatca tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg
     2701 gtcggataaa tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc
     2761 cattttgcta cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa
     2821 aaagatacac tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc
     2881 ccttttagaa aaagcaaaaa aaaaagaaag aaacttattc ttgctaataa actacgcgaa
     2941 aggagtctaa cgttgtttga tataacttag actgatcgtt aacttatttt ttatatttct
     3001 acatagttat ctttagaacc atttcagata catatgaaac aattacatat gattttttca
     3061 taaaaaaaca gtactgtcta gtagtataaa atatacaaat ttcttaaaaa ttttttcact
     3121 aaaatcacta cctgaaacag tctaaaacac ttatatatca acgtttaatg aaactatctc
     3181 cgtttcattt cagatacaaa taaatatagt cgggctccaa atccgaaaaa aaataccccc
     3241 agtagcttat cctaagctac tggagatgta taagtacggt catataacaa cggggtaggg
     3301 taaataaatg aaaaagatgg aagaatcatt attcaataac ttttttaaat acttcgttgt
     3361 aatcagttac ctgtccgttc ttaaatacca cagaataatc ttttttccca ttttcaagta
     3421 accgaagtgg aatatcttta ccaactttct ctgtcactgc attactgata cctgttagat
     3481 tagctaataa atctgataaa gattgagcat ctgtagaaat ctctgtatca gtatttatcg
     3541 tgattccttt atcttcattt acaagtttcc aagtaggtgg tatagctgtg tatgtttcta
     3601 caaatgaatt aagtttttca ttaagtgact tctcttttat atttccatct aaaaactctg
     3661 tatatatggc ttgagctata ctaaaacaaa gctggccttg ttctaataat tttacatcat
     3721 tagttagtaa agctgtgttc acgttatcaa tcgcttcaag aagagtatct ttggtgtccc
     3781 taacagcttt aggtgtgcct tctggaattt ccctacttga tacctcgtcc attttatctt
     3841 ccataaaccc cttaaaatca tatctttctc ccaaatccat agaagttttt gagaaagctt
     3901 tcatttctga gtctatttct tcaataatat ttaacatgtc tgatacatat tgtttaggct
     3961 gattcgtttt taatctatat gtggtaaata tctcaattcc tccaattatc aataaaattg
     4021 ccaaacaaat ccataataat tttttctttt tcatttttcc tcctatacac tgctgttata
     4081 acagtgacta atgtaaagat tttcccagca atcatcagac tattatttac agggaatcaa
     4141 aaaaactcct tagtaagctt acacctttag gagttcctgt ttgaacggta tgcataatac
     4201 atttaaatca atttaacatt aacacctcag tatatggtat ctctacatat acacggtctt
     4261 tttttggata gtactcgaca tttatattga tagcacttcc attgtctaac gtagctttag
     4321 cccggtacgt gttatcacca ttatcatgag tgatcgtcac atcatcacat gtccgattta
     4381 agttatactg ttcttgtaaa atctgagtta ccaatggtac agatgacttc tctagtccag
     4441 atgaacccgt cattcttgaa aaaattatac ctataatagc caatacaacg atacctataa
     4501 tgacaaactt cttattcata tttactttat tcaacttttt atctcctatc tccaaaatga
     4561 ttttctctca tcagtaactc attgacatcc ccaatagtac accaaagatg gctccagcta
     4621 cccctgctat catcaaaatc gtacccattt gttcatcttt ctctcgatat aagtaaccca
     4681 taataacagc aacagcacca aataccacag gaataaatgc taatgatact accatagaaa
     4741 tccaaccaat aatcaaatac agcttccctg tctcttgtcc atgtacgatt tgttccttca
     4801 tttcattaat tgtctgctca gtacttttct ttactgtgtc tgttccggtt gtctcatctg
     4861 tttcttgtaa tgctccgcaa aactggcaat acttactttc atttgttatt tctttaccac
     4921 attttctaca atacatgtct tctcctccta aaatcattca attgcttatt agctaactgt
     4981 ttactttatt aaatacatca gaaaacagct catttattgg tacacttaat atctcagaaa
     5041 gcattttcat ttgatagggt ttaggaatcg ttctccctgt ttgccacgaa cttacacatt
     5101 gctgtgtaac attcattttt ttggctaact cagtttggga aagtcctttt tcttttctgt
     5161 atcggctgag attacttact tttttcatga ttctcccctc ctgttttatt atatacaaca
     5221 atatgatgta tttcaactca taaaatatat aaatacttca aatgtcatta caaatacaac
     5281 aacttgttgt actctactga gaaggggggt gtattaatga aacagaagca atatgcaaag
     5341 gtcattagag aaaagcgaaa agcactcggg tggacacaaa aagaattagc taaaaaaatc
     5401 ttctctacac aacaggcagt agcaagatgg gaaaattctg taacagaacc taacctcgat
     5461 agcttaacag ctctttctag agccctagga acccctgtaa gccattttct agacaatgtt
     5521 gacatagatt atgaggaaga gtttttggct ctctatcgct ctcttagtac tgaagatgca
     5581 attcgaacaa ttgactatat gaagctatta aaaaggcaag aaaatgaacg caatcagcta
     5641 ttgaaagatt gaaaaataaa taacccaccg aactttaacg gtgggtgtat tgagatgaaa
     5701 taagattaag agctatggat aacctgtcta gtttaatata attgggtctc ttctattcct
     5761 tactctccgt ccatcatctc ttgttacact tgtaaattga taaataggaa ctaattcaac
     5821 tcctgataat atcaattctt ttattacttc atctatccct gcccctttcg ctagatatac
     5881 taaaaaacta ctgcttgctt tcacattgta tagtttctta atatccttag aagctcgttc
     5941 aagagtgaat ccttgtttaa caaagtagcc tctgttttct attaaagcat ttttcacgct
     6001 gttatccctg acatttcgta ggcgttcaca aacagtgtta ataagttctt tttctgtcat
     6061 tagatatgtc ccttgccacg ataagccctg taaaacttca tgtgcttcat ctaaaatcaa
     6121 ttgtttttcc ttgctaagtt ctgatcggga attttgagga aatactcttt tagcctcttt
     6181 ttcgttaaaa catatcttaa cccattcata agaaaaatat tgatatgtaa aatgaaattt
     6241 ttccagaagt ggaaggatat cttcattcaa tttttgaatc acagaagttg cattaaaaac
     6301 gtctaatcga tagacattgc ttctcttatg tttaaagttt cctaacgctt tctcttcctt
     6361 taacctattt aggtattcga gcatcttcaa aggaacatct tcatcatcta atttttttat
     6421 caatcctata aaagtcataa gtgatagtaa cttattacat ttatctatgt cataagtttt
     6481 accatagtaa gaactcattt ttttagctaa ttgttccccc gacaaaatac aagtcacact
     6541 ttccttacta tcatcaaaaa aattaacatc agaaagcaag acatcataga cacgtcgcat
     6601 ttcctctaga taattcctta ttgtcctgaa aagtttgtct ttcattgatt caagagtgtc
     6661 aaaaagtact tttgattcct ctttcaattt tcgaaaatgt gtaggataca agtctaggtt
     6721 ctctaatagc caattaaatg tttctacccg actgtctttc tttaaaatta gcatcacaac
     6781 tccaataaaa ttttcactga tatcacaatt actggaatga caataaaaaa tggaatgccc
     6841 agttttactg gtaaaaatac tagcagaggg attatgatcg ttgtgaaaca gacatcttaa
     6901 gtttttactt gacttaagta atttattcat atcaatggtt aacaatcttt cataaatctc
     6961 attaaaagac atgtcggagg aatcaaacag gcagtcttta aaccactgtt tcatttcttc
     7021 tttgtcgtca ttttttatca acttaacaaa atcggtttca ttgactagtt catactctct
     7081 ccctgaatca ctttgacaat ttttagaaca tgtcatggta aaatcaatcg gaagctcagt
     7141 aatatctaac atgttgtctt cattaattat tatcactgca tctgacttat atcctccaaa
     7201 aaacattcta ttcgaagcat ttacattgtc atcacacccg gggatgttct ttttcaagta
     7261 ttcgtaaaca gcaaccattt taccatagtc agtaattgct tcttttaata gaaagacaat
     7321 cttgtatttt tctagatttt cagagtaccg aatacttttt tgtatcgcaa acgcagaatt
     7381 atgaactaaa ttgatagata aaaccttttc tatgcttaag tatctactat catctttact
     7441 caaatctact accttcccct tctcatcttt aacagtgtta tcgacatcca gaataattac
     7501 tctggtttcc acaaaactct ccttgtcatt gcctttattc tttgtcttgc ttggaataaa
     7561 tgattgtgat gaatttagta tctctacaaa ctcatctctt gtaacttctc tatagttatc
     7621 taaacaccta tctcttacat cagttttttc tttttttgta actggcttct ctaataattt
     7681 ttcttgatct acataaattg gaatattaat cattgatgtt tccatttgtg tttcctcctt
     7741 ataaaattct gttaaagact aaaacataca gataataaaa acaaactctt tattactata
     7801 tgttttagtc ttatttgttt actcaacctt tataccgttc catgaaacta tcaatatcag
     7861 attttttaaa tctaatgacc gtatcaattt ttataacagg taacccgtat tgagaaacat
     7921 attttctaat cgttcctact gatacaccta gatattcact tgcctgctga tagtccatat
     7981 actctagagt gactccagaa ataatgtctt ctagcatagg ctttagcact gtaattatct
     8041 ctttcacttg ttgttcaact tgtatagaaa caatgctatc aatgatttgt agagacatat
     8101 ttccccctcc tttcgtgatt gcttgaacaa attttctaag aattatcttc gtattttttg
     8161 ctcaaaataa aagtattttg ttattaaccg attaatcaaa caaaaaatga ttaccagttc
     8221 atcgacatac acataatacc tcgataaaaa aggggtgtca acagctttgt aaaatttatt
     8281 tacaacaccc cttttttgag gtatactaat tttaggaggt gtggtcaata tgataaaacg
     8341 tccaccaata aattatttag aacgaaaaaa gatactcgga acaaaaataa aagctataag
     8401 aaagagtaaa aaattaacac aaccagcatt tggtcttatg attaacaacg gtcaattaat
     8461 tgacaaaaaa actatctacg aatgggagaa gggaacctat ttaccaatac cagagcgatt
     8521 atcccgaatt gctgatttgg gaaatatgag tatagaggag ttagtttgtg gcaatgtaga
     8581 agaatatatt ttgggaatta ttctttatag agatagcatt gtactagatg gtataacatt
     8641 tccagataaa aacctgttcc agcatcttcg tcaacagttc ccaccagtac actctaattt
     8701 agatacatgg ctggatagat attccaaatt agaaccagag atgcaagaat ttattgctaa
     8761 caagacttgt aataaagtta aaaatgaaaa aattagtctt ttcaatatct taaaaataga
     8821 agaattattc atcaatgcta ttgtagaaga atttgacaat aacattcttt tcctcactag
     8881 cagtatagaa gaactactag aaagaatggt agatgaatgg ctacctattc aattgaaaga
     8941 catgtcttat cccgaagaag ctgtgagaga aattactgat aatataaaca agctagaaca
     9001 aacgatttca tcaattggga aaaaatacac taagaaaaaa atgaagggag gtgataccat
     9061 ctagtggtaa gtactccttg taaactaaga ggagatgatt taatggcaaa aatatcaaag
     9121 tacaaaaaga aaaacggtca agtggcgtgg atgtataaag gacacattgc caccgatcca
     9181 cgaactggtg aaaaaataaa tactacgaga agaggtttta gtagcaaaca agaagctcaa
     9241 aaagattatg acgagtacag acatcaaata ttatacggtg ttaaaaagaa agcacctgat
     9301 atgacatttg aagacctgta taatgaatgg ataactcatc agcgtaccag tgttaaagct
     9361 tcaacaatcg caatctcagt aagatacgca aataatcaaa tacttccagc atttggtaag
     9421 cttaaactat cgaatatctc tgtcccatat tgtcaaaaag tggtagatga atggcacagt
     9481 aaatatgaaa gttacgatta tatgagaaaa cagactgcac aaattttacg ctacggggtt
     9541 gcaatgcaat atattgacaa taatcctatg gaaaaaacac ttcttccacg aaaaaaagag
     9601 tatgagaaaa atcgtaaatt ttactcaaaa gaggagctta ataatttact ggatgctttt
     9661 aaagattttg gtaacatgaa acaatacgcc ttcttcagat tattggcata cacaggtatg
     9721 agaaagagtg aagtactcgc tttacagtgg aaagacatag acacgtttaa taaagaacta
     9781 catgtcaata aaactcttgc tgtagatgaa tttggtaaag ttataattca atctccgaaa
     9841 acaagagctt ctagacgagt tatctcttta gatactgaga ctctttctat cctcaacaac
     9901 tggaaattac agcaaaaaga agagtattta aaacttggat acaatactag ctctaaagag
     9961 caacatgttt ttacaacagt taaaaacact ctatacattc caaacactgt taatgattgg
    10021 ttaagatata ttttgaaaaa atataacttg cctcgtatta cacctcatgg gtttagacat
    10081 acacatgcta gtttattatt agaagcagga gaatctgtca aggtagttca acaacgatta
    10141 gggcatgaaa atagtaaagt gacattagac atctatgcac atattacaaa taatgcacct
    10201 aagaaaacag gtcaagactt tgctgatatg atggctcatc agtaaaagag ctggtcaaaa
    10261 tctggtcatt tctagtatac aggcaaaaca aaaaagctag aacccttata tatcaagggt
    10321 tctagctcct ataacaggtt tacccaacac tgccttccat ctcataactg atcaatcgat
    10381 tgagttcgac tgcatattcc attggaagtt ctttggtgaa tggttcaaca aagcccatga
    10441 cgatcatttc agttgcttca gattcggtca ggcctcggct catcagatag tagagttgtt
    10501 cttctgagat ttttgagact ttggcttcgt gttctaaaga gacttggctg ttgtggatct
    10561 cattgaatgg gatcgtatcg gatttcgacc attcgtccat gatgatcgtg tcacattcga
    10621 tatgagagat cgaacccgca ctgtttttgg caaaggttac ttgtcctcga tagtttactt
    10681 ctccgccgtc ttttgaaatt gatttagaga cgatagagct agatgtattt ggtgcattgt
    10741 ggatcatttt tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg atggagagca
    10801 tggtgcctcg tgcacctttt ccatctaagt aaacacttgg gtatttcatc gttgtttttg
    10861 cacctaggtt tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt gctcgtttgg
    10921 ttactaagtt gtacacattg tctgaccagt tttggatcgt tgtgtaacgg caatacgcat
    10981 cttttcttgt aaagatttct acgatggcgg catgcaggct gttacttgaa taagtaggtg
    11041 ccgtacaacc ttcgacatag tggatgcttg ctccttcgtc aacaatgatc agcgtacgtt
    11101 cgaattgccc cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga acatcgactt
    11161 tgacgccttt tggcacgtaa ataaaggtcc cacctgacca tacggctgaa ttcagcgctg
    11221 ctaatttgtt gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat aattcagggt
    11281 attctttcaa agcagagtca gtgtcagtaa agacgattcc taacttttcg aattcatctt
    11341 tcatattatg gtacacgact tctgattcat attgtgcgga agcaccggct agataagctc
    11401 gttcagcttc tggtatacca atcttttcaa atgtatcttt gattttttct ggtacgtctt
    11461 cccagtcacg agcgggtttg tcacttggtt tttggtaata tttgatggca tcgaaatcga
    11521 tgtctgaaag gtcggggccc catgtttgca ttggcatttt gttaaatgtt tctagagatt
    11581 tcagacggaa ttcaagcatc cattctggtt cgcctttgat tcttgacatc tcacggatca
    11641 cttcttctgt caagccttct cctgtactga aaaccggttc gacatcatcg tgaaacccga
    11701 atttatattc ttctaattct ggtacgccca tgttctcact cctcttcctt gtggtaatga
    11761 tggaaagctg cggtaccatc gttttccatt gcttttccta gtgctttcca ggcaagtgtc
    11821 gcacatttga tccgagcggg aaatttagct acaccaccaa gcatagcagc atcgcctaat
    11881 tggtcgggat ctttgacttc ttttccttgg acaagctgta gaaagtctac agttaaatgt
    11941 tctgcttctt ctattgattt tccgatgacg gcgtctgtca tcatcgaggc acttgccgta
    12001 ctgatggagc agccactgcc gtcaaaggcg atatttttga tgattccgtc ttttacatcg
    12061 acttgcaatt cgatcacatc tccacatgtg gggttgttca attcgatctt gcttgtcgag
    12121 tcagtcaagc ttccacgatg atgcggatgg gaagaatgat ccaagatcac ttgacggtat
    12181 aaattgtcta atttagatag tcccatgttg gaaaaactcc tttgttgcca tgattgcttc
    12241 aactaaacgg tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc gagcagtcgc
    12301 tgatacttca aggtacttca atagcggttg cgcacaatga tgacctgctc tgacggctac
    12361 cccttccatg tctaaagctg tcgcgacatc atggggatgt aacccatcca aattgaatgc
    12421 aacgactcct gtccgaaaat tcgggtcttg tggaccataa acagtcaatc catcaattgc
    12481 ttgtaatttt ggcaacacat aagcggctag ttcttcttca tatcgatgga tattgtccat
    12541 accgagtttt tgcaaataat cgattgcatg gcctaatgcg atagcgccgg cgatatttgg
    12601 tgtccctgct tcgaatttcc aaggtagttc tttccatgta ctgtcgtata attcgacaaa
    12661 atcgatcatt tcgccaccaa attcaacagg ttccatttct tctaaccatt ttcgtttacc
    12721 atataaaaca ccaatacctg ttggtccgca cattttgtgt ccgctgaaag caaagaaatc
    12781 acagtctagt gcttggacat caatggccat gtgcggggca gattgagcac catctactac
    12841 gatgaccccg ccgttttcat ggacaagttc agctaattct tgaacaggat tgaagacacc
    12901 taagacattg gatacatgag caatggagac gattttggtt ttgtccgtaa tctttttcgc
    12961 tgcatcctcc atatccagga agccttcttc tgttagttcg atatatttca agacagcacc
    13021 tgttcgtttt gccaactgct gccacgggat aacattagaa tgatgttcca tgtaagagag
    13081 cactatctcg tctcctgctt tgatatagcg gtcgccgaag gttctggcta cccaattcaa
    13141 gcttgtcgtc gtaccacgag taaacagcac ttctgctgtt tcttttgcat ggatgaacgc
    13201 ccgtactttt tctcttgctt gttcataatc atgggtcgcg cgttctgcta acgtatggac
    13261 accgcgatga acattggcgt tatcgtgttc gtaatagtac gctaatgcct ggagtacttg
    13321 ttttggcttt tgggtcgtcg ctgcattatc cagataaact aaaggttcat cattgacgtc
    13381 ttgaaataag ataggaaaat cattgcgtag ctttttagca tcgatcatcc attcaacttc
    13441 ccttcgatta cttcgactaa ttctttccga acttgttcta cagggattgc tgttaagaca
    13501 gaaccgagga atcctcgaat cactaagcgc tctgcttctt ctttatgcaa tcctctactc
    13561 atcagatagt acatttcttc tggatcaact cgtcctacac tggcagcatg tccagcagtt
    13621 acttcgtttt catcgatcaa aagaatagga ttcgcatcac cacgtgcttt atcagaaagc
    13681 atcaagacac gactttcttg ttgggcatct gcaccttttg cccctttcaa gatgtggccg
    13741 ataccattaa aggtcaatgt tcctttttct cggatcactc cgtgttgcaa aatatgcccg
    13801 atcgtatgag gggctttatt ggttactcgt gtatcgattc cttggatttg tctgcccgag
    13861 ctgattgcca cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc tgagtcaaag
    13921 tcagcgatca catgaccgtc attcatgaca ccaattgccc agtcgacaga agcatctcgt
    13981 aaaatgtgcc cacggcgatt catataagaa gtaatatttt ctcctaattg atctacggct
    14041 gaatatttga tttttgaacc agctttagcg atgacttcca cgatgatatt acctgatgat
    14101 tttgctactt gttctttggt tgtctggaaa cgttccagat aagaaaattc actatgttca
    14161 tctgccacga tcaacacatg cttgaagaag tgctcatcgg atgcgccatc ttgaatgaat
    14221 aaggactcga gtggttcatc gatcacgaca tttttaggca catacaggaa aataccgctg
    14281 ttcataaaag ctacatggag tgcagtcaat tggtcttcgt tcatgtttac tgcttttttc
    14341 atataatatt cttggactag ttctggatat tcgatcattg cagtgaacaa gtcggtaaaa
    14401 atgactcctt tttctgctaa ttccacaggc agttgttcaa aaatcgtcca tgaaccttgt
    14461 tggacaagca caggattgtc tttcattgca tcaaatgccg gaatcgtgcc tgtttcactg
    14521 atggtttgtg tttctttcac atcaaataac gaccagcgat ggaatttcac ccgatcgata
    14581 tgcggcaatg gcagttcatc tgctttcgct agtgcgtctt gacggaaggt tctcatccaa
    14641 tcaggttcgc ctttacttaa agaaaaatca tttaccgcgt caagataatc gagccagttt
    14701 ttttctttca ttcttgctcc cccttacgct tcttcttctt tatagtcgat tcctaattct
    14761 ttactgatac cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc attccctgtc
    14821 atgactactc ggccttccat catgatgtga acgacatcag gtgtgatata gttcaataat
    14881 cgttgatagt gggtgatgat caatgcaccg aaattgtctc cgcgcatttc atttactcct
    14941 ttagcaacga ctttcaaagc atcgatatcc agacctgaat cgatttcgtc taaaattgca
    15001 aatgtaggtt ctaacatcaa caattgcagg atctcattcc gtttcttttc tccgccagaa
    15061 aaaccttcgt tcagataacg ttcagccatt tcttctggca tatttagtaa agccattttt
    15121 tcatctaact ttttcaaaaa tgccataaca gaaattttgt cgttttcatc acgtttcgca
    15181 ttgatcgctg cacgcatgaa ttccgcattc gtgatacctg gtatctcact tggatattgc
    15241 atagctaaaa ataagccaag tcgcgcacgt tcatctactt ccaagtctaa aacatttttc
    15301 ccgtcaaaca aaatttcgcc ttctgttact tcatagtttg gattgcccat gatagcggca
    15361 gataaggtag attttcctgt gccgttaggt cccatgatgg catggatttc tccggttttc
    15421 attgttaggt ttacgccttt aaggatttct ttttcctcga tcgacacatg tagatttttt
    15481 atttctaaga cagacatgca ttataccccc aaattctctt tcgttctcac tcattttaga
    15541 ctaattgaga atgaagcgca atgaccttcc ttactaaaat caaatatctt ttatttatta
    15601 ttaaacaatt ttgatttcta aattagaata ggtataaaaa agatgagaaa taagccatta
    15661 cagacttatt tctcatcttt tttgttccat accttatttt gcatcagcct ttactggttt
    15721 aacagagccg ccccatttgt ctgtgatcca ttcttggact tctttgcggt gaagcacttc
    15781 aatcagtttt ttgattttgt cactgtcttc atcaccttta cgagtcgcaa taatattcac
    15841 gtaaggagag ttgtcctttt caagcaatac ggcatcttct aatggattca accctgcgcc
    15901 gtaagcgaag tttgcgttga ttgcaactag gtcaccttca tcattttggt acgtagaagc
    15961 taaaagtgat gggtcgatcg tatggttgaa cttcaagttc ttagggtttt cttcaatatc
    16021 atcgaatgtt gctgtttcca gatctactcc atctttgact ttgactaagc cagcatcttg
    16081 tagaattgtg atgatgcgtc cccagtctga ttcagaattt gaagtaatga ttgttgcacc
    16141 atcttttaat tcggaaacat ctttgacttt tttagagtac aagcccattg gttcgatgtg
    16201 gacagcaccg gcattgacaa agtcatatcc tttttctttg atttctttgt tcaaataagg
    16261 aatatgctgg aagtaattgg catcaatgtc gccttcttcc aaagattggt tcggtaatac
    16321 atagtcatcg aatttgacga tttcaagatc gattccttca tctttcaata atggtttcac
    16381 atgttccaaa atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg tcgtgtcgtc
    16441 tgctttattt gctgaatctt tgctgtcgct gttgttaccg catgctgcta atcctacagt
    16501 cagcaaaagc gctgctgcaa atccaaaaat tttctttttc atatcctaca tccccctata
    16561 tcctattatc ttttgtctgt tttcttagtt aagaaatcac cgattccttg aacgataaat
    16621 acgattagta aaataattaa agtcgcaacg aatgtcactg ttagattacc acgctggtag
    16681 ccttcctgcc aagcaagacc tccaagtcca cctgcgccga tcgcgccggc catcgcagta
    16741 aatccgatca tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg aatactttca
    16801 ggtatcaaga ccttccagat gatttcccag taacttgctc ccattgcatc tgctgcttcc
    16861 agtacaccag ggctgacttc acgaaaagca atctctacta gacgggcata aaatggtgct
    16921 gcggataaaa caagagctgg aatggctgct tgcgcaccta gcatagtgcc tacgattgct
    16981 ttagtaaatg gaatgatcaa aaccatcagg atcataaatg gcgttgaccg gaaaatatta
    17041 ctgatgatcg atacgattcc ataaatgatt cgagcatacg gtttgttttt gcgtccaata
    17101 gagtaaagga tcaatcccaa aactaatccg atgatcgtca ctaagaccat tgagattaat
    17161 gtcatatata gtgtatcaag gatagcctga ttcatcgttt ccgggttgat ttgtttaaaa
    17221 tctagatatg tttctgaaaa gcttttatcc acgatggatc acctcaattc ctactccttg
    17281 ttctttgatg aacacttctg cttgatctaa ttctttggtt tcaccagtca tcaagacagt
    17341 caatgaacca aaggaacctt ctttcacttg tttgatcttt ccatacacaa cgttgacatc
    17401 gatgttatag cgtcgaatcg cttgggaaat gactggctcg ttggcatttc tttcgctaaa
    17461 ggtcaaagtt gccaaacggc cgcttggatt ttctttgatg agttcagcta atagttctgt
    17521 cgaatcagct tctggttcga tgtcttgttg tacaaagcgt ttggttactt cttttttcgg
    17581 ttgtctgaag acagtcaata cgtctccttc ttctacgact ttccccaact ccatcacagc
    17641 gactttgttg cagattttgc ggatcacatt catttcatgt gtgatcaaga cgatggtcaa
    17701 attcaatttc ttattgatcg ctaacaataa gtctaatact tcttctgttg tttgcgggtc
    17761 caatgcgcta gtagcctcat cacaaagcag gatctcagga tcatttgcca atgctcgtgc
    17821 gataccgacg cgttgtttct gtccgccgga aagttgtgaa ggatatgctt gtccgcgtcc
    17881 ttctaacccg actaaacgca acagttcttc tgcccgttct ttacgtttgc tctttggtac
    17941 gccagctaat tccagcggca gctggatatt ttcaagtaca gttcttgacc ataacaggtt
    18001 gaaatgctgg aagatcatac cgattttctt tcggaatgta cgtaattctt tgttttttaa
    18061 ttttgtaata tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct caagtccatt
    18121 caggagacgg actaatgtac tttttcctgc gccagaatag ccgacgattc cataaatatc
    18181 ccctttttca acgtttagtg aaacgtcatt gacggcttgg atgtttccgt ttttcccatt
    18241 gaatgtcttt ttgacattcg ttagttggat taatgacatg ccattcacat ctttctctta
    18301 tgatttttca aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac gaaagcttga
    18361 acttccgtgt taccaccttg atttaccgtt acttcgcaat aacagcctct tccagtactt
    18421 ggacttagct tctttccgta tactgtcgcg ctgtaacggg cactcccgta gtaagtttgc
    18481 ttacgctcgc ttactctgct ctaagaccat cttccatctc attttcgtta cccattttca
    18541 gcaaacaggg ctctcttcaa acgtccgtga catgtactct tcttttcaaa gctttctcgt
    18601 ttcatatagg attgcttatg attatagcaa ctggaagaat cagtgtcaac ttttttcaag
    18661 tgattttctg attttataat tcgtcaaatt cttttggatc aacatctttg aaacttaaga
    18721 tccacgcatt catttcatct gaatcattca agatattgat atcttcaccg attttatcat
    18781 taacagaaga aactgtaccc gttagcgggc tggcaaattc attgaccgct ttttccgctt
    18841 caacttcgat cagaggttca tcttttttta gcgattgtcc tgcttttggc agattggcaa
    18901 acgtgatgtc tccaagttct tcttgcgctt catttgtcaa accaacacag tattcttttc
    18961 cattaaataa gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc attttatatc
    19021 agttctcctt cataaatttt ttcattgaat ccaattgcaa caagctggtc ctctcgtaag
    19081 atcagtggtc gcttgatcag cataccatct gtcgataaga cttggctcgc ttttgaagcc
    19141 gtaaactcgc ctacttgatc tttcagtcca agttcccgat atttcatccc gcttgtgttg
    19201 aacaggcgac ggattggtac ttgactcgtt tctagccaag tctcaatcgt tgaggccttc
    19261 ggtacttctt tgatcatatc aacggtttga taactaacgc catgctggtc taaccacgct
    19321 ttggcttttt tgcatgttga acatttcggg taccagtaaa aggtgtacaa ttttcttacc
    19381 tccttgaaga tcttgcaggt gcttcatttt ggtatctcat cgataatatc aacccgatac
    19441 cgatcatgtt ccctaaaatc gaggatcctc cctgactaat gaaaggcaat gggatccctg
    19501 ttaaaggaag taatccgata tttgctccaa tattctcaaa gacatggaac agcagcatca
    19561 tgatcaaacc gcttgcgata taggcgtaaa attcattatt cgtatcgaaa cacacccgaa
    19621 tcatacgata gattaaaata aaatacaaga aaatgacgaa tgcaccaccg ataaagccga
    19681 agttttcacc gataacggta aaaatcatat cggactcacg aacaggcaca tagatattgc
    19741 ttacgttgaa tcctttacca aacaagccac cggtaccaat tgccaaaagt ccttgggccg
    19801 gctgataact cattcctgac gtatcatgga aagggtccag ccatgaatca atacgtgcaa
    19861 actgataaga tttgaatcca actttataaa gcaagtctct tccgccttca gtcgtaacca
    19921 agaagatcgt tcctgctcca acgactactg ccaagattac tacaggtgcg atgatgcgcc
    19981 aagagattcc agacatcagg aaaatcccgc caaagatcgc aagaaagaca agcatcgttc
    20041 caaagtcatc ttgggccatg atcaatgcta aaaccggtat tgtcacgatc aagagcttcc
    20101 caatcagcca aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta tgtttagtta
    20161 cgatcagtgc catcatcaag atgtacgcaa tcttcatcaa ctctgctggc tggaaagtaa
    20221 acgcaccgaa tcgaaaccag tttttagacc ctgttgaagc agctaaattc tgatcataga
    20281 atttgagcaa gagtcccatt accactaacc ccaaaccata aaggtaagga gtcagtttcc
    20341 agatccattt ggaattcaaa tgcatgatga caacgattgc tgccgctcca actaaatacc
    20401 agacaacttg catccctacg cctttcaaga ctgctggatt gttcggatca tggctaagtg
    20461 ctacatataa tgagagcaga ccaatcaaac ataacagaaa gactggtaaa atcacgccat
    20521 aatcaatacg attatcgttc gaagctttta attttttttc catgtttcat cccttttctt
    20581 aaaaaccata ctgctgatta ttatagcggt ccagttagat aatggaaagt ctttccatag
    20641 acatttggga aaaattaact ttccgtttgt gcagttgctt gagcaaatgc agtacaaaag
    20701 cctactgctt atctttagtg tatcatagaa ctttttttga tacatgcaat tatctaccag
    20761 ctgagattct cctcgctgtg agaagtttct gtgctttcat tgtatcgaag gatctcttcg
    20821 gcaatctcta gcagctgatc agaaaccaga ttggttcgtt ggatgaaata aaaatatcga
    20881 tggaaattca acggagtcat tggcacattt tctggaacag agcgcttaga caaaatcgag
    20941 cgaccgattc cttccttcag caacgcaaca attacatcgt tacttttcac gatcatcttc
    21001 ttatcttgga tattcatctc ttcaaaataa cgctgcgtgt aatgaaaaac accagagttt
    21061 gcttctctta caagccacaa tttgcttttt gggtccccag cgatgactag ctggtcttcc
    21121 atcaaagagt atctttgtac gccggaagtc tctaatggct tttcgataaa accaaaatcg
    21181 gattcatgtt tcgctacttg ttctaatgat tcatgagaat tcgtgatttc gatctcaaaa
    21241 tgcactttag gaaacctttt gatcagatgt ttcatcaact gaggcaaaag atagacagca
    21301 aaggtgtggg aagcaacgat ccgacatact tcttcttcat tttgttcatt gagcaatttt
    21361 tgctgagttt cttcccattc ttctaacaaa accagtgtcc gttcatataa taagtcggct
    21421 tgcttagttg gaagcatctc ttttcttccg ttacgttgaa aaagatcgat attcaattcc
    21481 cgctccaact gtttgatttg attcgagact gctggttgag ataaaaacag tacttctgct
    21541 gctctggaaa aatttcttgt ttcatatact gctcgaaaag tcgttaataa cttaaacatg
    21601 gcaccacttc cataactttt tatgataatt actataaaaa ctatttgatt taaatataca
    21661 aaaaaccatc tataatagaa atgtacaaca aaacagttgc tgatccaact agtaacttag
    21721 atgaagacaa tcagctgtct gcttgctcgt aatcatacat tcctattcat tttacaatgt
    21781 attcgttcat cttggtacta aaatctatta aataaaaagg agaatattat atatgaagaa
    21841 ctttttgaaa attattccga tcccgatctg cgggttgatc cttgggttag cttcccttgg
    21901 aaatctgttt aaagactatc accatgttgc tttaggcaat ctaactggcg gtatctctat
    21961 gattcttatg atattcattt ttgttaaatt gtttatctta ttcgaacaca cgaaacaaac
    22021 gttgcatgat ccaatcatcg cctccgtttc accaactttt acgatgtcac tcatggttat
    22081 ttgtacttat tttgtttcat atgaaagtat tgcaccaatt gtcaaattca tttggctgtg
    22141 cgctgttatc ttccaagtga tccttgtctt ttatttcaat tatcaccatg ttatcaaagc
    22201 tgatctttca attgaagcaa tttatccaag ctggtttatc atttacgttg gatttggggt
    22261 catcactgta actgccggga acttcttccc acttattgga aaaattttct tttggatttc
    22321 attgatctgc tatgcgttct tattgccgat catcatcaaa cgtgtctttt tcgtaagaaa
    22381 tatggctcat ccgacacgtc cgctgattac gatcgttgca gcacctggtt ctctttgcct
    22441 aacaggttat cttaaaaact ttgctgaacc taatttttat cttgtcgtag cattgttcgc
    22501 tttatctcaa gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt tcaagcttcg
    22561 tttttatcca agctatgcag cctttacatt cccgcttgtt atctctgcaa cagctatatt
    22621 tactactgtt cattacttca acagtttagg tatctatagt agcgtattgg atttcttaaa
    22681 agttgcggaa tgtctgtttg caagtgtagt tgtcttctac gttcttgctc attacgtacg
    22741 tttcttaatt aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa tcgcttaata
    22801 atcgattcaa taggttgtga aaaagctgtt ctgcatcaag taataagaac ggccaaacaa
    22861 aaacagctgt tcatgttttt gtactggttg ggcttattac cgcagatgca agcttttgaa
    22921 caccgtttac caagaggtcg taaaagaagt ggtcagcttc aagaaataag aaggaattta
    22981 cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa gctacttctg
    23041 gaacaccgtt tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt
    23101 ttgtcaaaat actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga
    23161 aaggaaccga tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg
    23221 tccgcgaaat cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc
    23281 ttgctattta tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat
    23341 taggaaatac tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca
    23401 aactattaga attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc
    23461 aaattggtgt aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg
    23521 cttacttgat tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag
    23581 gaaacgctgt ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag
    23641 aggaagaaaa aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga
    23701 ctctcccttt tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt
    23761 tgggtggtac actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt
    23821 ctgttgtcga attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg
    23881 tctatctgtt tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg
    23941 atacgcagaa aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt
    24001 gtttggtcaa cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca
    24061 gcagctggtt tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat
    24121 tcatgaaaga aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag
    24181 tgatggcttt actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg
    24241 tgattctcgc atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc
    24301 taacaacaac aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt
    24361 cagttttcca ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt
    24421 tcgatttgcc tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc
    24481 tttatacgtt cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg
    24541 aaaaggcgta cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa
    24601 atattcttca aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc
    24661 tgaaattggc tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa
    24721 gccgataggt gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc
    24781 ctttttctct atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa
    24841 accgaggaaa catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac
    24901 gtaaaatcaa attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat
    24961 ataaacatac gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta
    25021 atgaagaaaa aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg
    25081 agttcgaata tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga
    25141 agctagcctc agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag
    25201 aagcggctct gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg
    25261 ttgatctgca agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg
    25321 atatcgattg tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt
    25381 tctttgcgaa aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg
    25441 gcgctcgtga tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag
    25501 aatacaaccg attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt
    25561 cttatgaaaa ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca
    25621 actactcgat tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta
    25681 tcggcgcttt gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat
    25741 tgttgtttgg tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg
    25801 gtggaatcca attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag
    25861 aaacgaaaca gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat
    25921 tgaagcctca ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac
    25981 tgtgacaaaa gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt
    26041 cttcggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct
    26101 tatttcttga agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt
    26161 gctgctttta gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt
    26221 ttcagcaagc gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc
    26281 aatttttctg tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg
    26341 atttccattt tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt
    26401 ctgcggtagt tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc
    26461 tcgcgcagat tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat
    26521 tcttgtttgc ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc
    26581 aagaaggttc ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt
    26641 tctgtcaaat ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta
    26701 ggagatactt gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg
    26761 ataatctctg cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag
    26821 cttgcttctg acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga
    26881 ttgattctca ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc
    26941 catcctgctt ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc
    27001 gtaacttttg tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca
    27061 atcatttgat agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca
    27121 gttggcaaaa gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg
    27181 acgatggctc cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc
    27241 aatcgttctt tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga
    27301 taagtaacga tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca
    27361 gaatagccat agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc
    27421 gcagattccg tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc
    27481 aattgaacaa gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc
    27541 attttggctt gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac
    27601 tgctcgattt tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct
    27661 gctgataaat tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc
    27721 cagtccgctt ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt
    27781 cttagttgct tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc
    27841 ttcactggtt tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct
    27901 cttccggcat ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg
    27961 attgctttta attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc
    28021 attggcaacg tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc
    28081 aatcctaata aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt
    28141 ttgtgctttt gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc
    28201 gctagaatta gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt
    28261 tttcaacaac gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg
    28321 ctcatctccg tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata
    28381 attttgatgg atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc
    28441 gaatgtttct tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt
    28501 gtccccgaac atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga
    28561 ctcatcttag tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta
    28621 atgaacatct taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag
    28681 ttattgatca tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat
    28741 cctaaaaaac gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga
    28801 actttttctt ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt
    28861 tcatggattc catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca
    28921 tacactgctt gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct
    28981 tcctgaccac tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt
    29041 ttcgctgtta gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga
    29101 gccttgatat ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct
    29161 tctgctagtt ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt
    29221 tccatgtttc ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag
    29281 agaaaaaaga gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga
    29341 tgaaaatttt cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag
    29401 gaaaagagaa acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg
    29461 tatcggattt agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta
    29521 tagtacgtca caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac
    29581 tacgcttatc tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct
    29641 gttgcgtgct tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt
    29701 gtatcaatta gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc
    29761 cactgccctt gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt
    29821 agcaactggt tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc
    29881 agcgtttggc tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt
    29941 gttgagtctg tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc
    30001 tgccaaacag attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac
    30061 aacgatgatc atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg
    30121 ccaattgctg catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc
    30181 tgggattgcc actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag
    30241 tgaaagaata cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt
    30301 cgtcacgaat gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg
    30361 tctgctccct gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg
    30421 gatcttcagt tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg
    30481 ctccagtgtt tccagtgcat ttggttatcg tggcgtcttt ctttcgactt ctcttcttgt
    30541 tttggtcaac ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc
    30601 agaagaaaaa gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata
    30661 agcgtaaatg aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt
    30721 ttaggcctgt tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt
    30781 tttacaacag taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa
    30841 tagtactcct gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc
    30901 taatttaatg aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt
    30961 ggctacccat tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa
    31021 tattttttct ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca
    31081 aatcatcgtg tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt
    31141 ccagccaata cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc
    31201 tttttcatag acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac
    31261 ttcatctatc aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt
    31321 tttccgatct agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt
    31381 ttcaggtttg actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt
    31441 caaatgaaca aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata
    31501 agtaggaagc atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag
    31561 attagcacca gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag
    31621 agaagcgact tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc
    31681 gtttttgcgt ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc
    31741 taatgtcaat gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt
    31801 atttagccat tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct
    31861 tgatccagcc tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa
    31921 tcattacttt ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga
    31981 agcaaaaacc aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa
    32041 tgatgcccat caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc
    32101 cttcttttaa agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg
    32161 ccgctgtaca taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata
    32221 agaatagatt agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat
    32281 tcgtttttcc ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg
    32341 ctgggagcat cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga
    32401 tcagcgctgc tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg
    32461 aaatagttgc taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat
    32521 agataaacaa taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct
    32581 tcgcgcggtt ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca
    32641 tcaaacaacc tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat
    32701 tatcagatac gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata
    32761 caaatattaa aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga
    32821 cgctcgctcc ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg
    32881 caaataaaat agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg
    32941 cgctcatcag catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc
    33001 aaccactgat gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac
    33061 catctagatc tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac
    33121 caatcccaac gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat
    33181 cacttgtgat cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc
    33241 cccatttgct aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg
    33301 aacaaatcac ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc
    33361 aactttattc atattattgg atattatgaa ctttttacac aagtatttca agtataaaat
    33421 gaataaaaat taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc
    33481 ttttgttagc catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt
    33541 tgtttcttga tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa
    33601 tacaactgct tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg
    33661 attatcatcc aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc
    33721 tgtacacttg aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc
    33781 caagcttgtg gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt
    33841 cgctagatct tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc
    33901 tagtccttga cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc
    33961 accatcaaga gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt
    34021 gaagttcttt tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag
    34081 gcctgcgcgt tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat
    34141 cgtttttgaa agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt
    34201 gtctactcca cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg
    34261 tccagtagct acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt
    34321 gatttctttg ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag
    34381 gaaatattca aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat
    34441 cccgatttga gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc
    34501 gttttcgtcc gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc
    34561 ctttaacaaa agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg
    34621 tgttttgctg ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac
    34681 gagttgaagg tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca
    34741 tcccttaatt atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat
    34801 gatagtcaac caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc
    34861 ataaaaaggg ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt
    34921 ttcaaaattg cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag
    34981 atgttatgag ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag
    35041 atacatgaat tactttatca gtgatatgca ctttttccat gaacacttat taggaaaaaa
    35101 cgactttgct ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag
    35161 ctggaatgca gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca
    35221 tccgcaatat gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac
    35281 aatccacttg atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa
    35341 tgatcctagg cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt
    35401 taaattcgac catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga
    35461 cactatccgc aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt
    35521 caatgtaggc gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac
    35581 tccgttatct gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc
    35641 gtgaaaaaac tgccctatat caagtattaa acaaataaag ataattactc atatttttca
    35701 tttgagtagg cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt
    35761 ctgtcacaac tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt
    35821 tttctgtaat tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca
    35881 taataaaatc ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa
    35941 tggtcctgca aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc
    36001 taagacacga cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt
    36061 attgaaatat ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc
    36121 ttgactatcg tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc
    36181 tataataata ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc
    36241 taagagcatt ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc
    36301 aaagtaatct agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac
    36361 aaatgcacca ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc
    36421 aaattttgca tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg
    36481 gatcttcaca aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat
    36541 aaggtaattg acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa
    36601 attcgctgat tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac
    36661 gattgtcggc ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat
    36721 aaacaaagac acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc
    36781 taaaataagc gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc
    36841 ccagcgatcc actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag
    36901 taaagtagca aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat
    36961 cgcatattgg acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa
    37021 ataatttctc ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct
    37081 tttctttttc attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa
    37141 aaaatacctt tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa
    37201 taaatcagca aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac
    37261 taatttgcgt cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg
    37321 tctttttata tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc
    37381 catcagaaaa taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac
    37441 tgctttcaat ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac
    37501 agtgattttt aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa
    37561 ttgataattg cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc
    37621 atcaggatgc aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc
    37681 catgattttc acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt
    37741 actaggtttt tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat
    37801 ataagaatga cttcactagt tattttttga cagcacgaac taattgatca aggaaatact
    37861 ggatgtcgtc ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg
    37921 gtgtatcttc tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac
    37981 aagctgaacc agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat
    38041 ttgcttcgcc aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat
    38101 ttacttgata agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt
    38161 tatatttgtt gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca
    38221 taccccagat ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc
    38281 ctaaaagcaa tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg
    38341 gcccattgat tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga
    38401 tcgtttggtt tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta
    38461 aaagttcacc gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca
    38521 cagagaccaa gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc
    38581 ctttttcatc tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg
    38641 tattaagaac agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac
    38701 gcgagaacgc tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga
    38761 tgatctcgtg aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt
    38821 tttcatgcgc gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca
    38881 tgattgccgt catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca
    38941 gataaatagt tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata
    39001 aaatagcgaa caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag
    39061 aaaaaaggag ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac
    39121 aacttctttc cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg
    39181 actcatcggt gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt
    39241 aacgattgtt aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca
    39301 aatatctttg attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg
    39361 tgacgcacag gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc
    39421 aagcgttgct cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc
    39481 accgatcaca taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt
    39541 gctgttcaaa tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac
    39601 aactacgatg tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat
    39661 cgtaaataaa ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc
    39721 taaagtcagt actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt
    39781 gatcggttca tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac
    39841 gacattgatc gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat
    39901 atagtaatca ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat
    39961 actttcttcg atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc
    40021 taattctgtt ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact
    40081 aaaaatcttc aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct
    40141 ctattcttcg atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt
    40201 aaggaagtga aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc
    40261 agttgtcgtg tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg
    40321 tcacccaatg attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt
    40381 tgccttcacg tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac
    40441 gctcatgatt gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa
    40501 tcgtaggaag tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat
    40561 cagccgtatt tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat
    40621 aataggcaag gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc
    40681 atttcttata cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct
    40741 ttcctgacct tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag
    40801 ataactcgat tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat
    40861 aagtatattt tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac
    40921 tttgatcttc aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct
    40981 gagtgctggc taatttttta atttttttat ctactttgaa atataaaggt ttatccacta
    41041 cttgattcag ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa
    41101 atcagtttga ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt
    41161 gtaagataat gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt
    41221 gaaacaagat ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc
    41281 agataaacca gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat
    41341 gggagaaaca gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca
    41401 tttccttgca tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca
    41461 accgcttcaa cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa
    41521 gcaatttcca gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc
    41581 agatatgaag aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc
    41641 agataagacg tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt
    41701 tgatatggct gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat
    41761 cacggaacaa gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga
    41821 aaacgcagat tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac
    41881 agataaactg gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt
    41941 gatcgtaact gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt
    42001 tccgttattc aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc
    42061 agaagaattc cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc
    42121 aatgcctcag aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg
    42181 cgattactac ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt
    42241 gaaaaaaatg atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc
    42301 aacaaaagaa aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga
    42361 taagatccca gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt
    42421 gctttcaaat actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa
    42481 caaaccagtg gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca
    42541 tccatttcgg aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct
    42601 agaacaatca agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc
    42661 ccatgcattt gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg
    42721 gacagaagaa gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga
    42781 tggtctgcct tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc
    42841 tgatgcaggc ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat
    42901 cgaggaattc tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca
    42961 acaactttta ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc
    43021 aaaaaacctt gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct
    43081 agcgccagaa aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa
    43141 gaaataagaa ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt
    43201 ttcgaagaag ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt
    43261 caagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta
    43321 ctaccgagaa actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga
    43381 cctgagtatt agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct
    43441 aataccgagg gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct
    43501 gcatcaagta ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga
    43561 tagaaggaag tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa
    43621 ttgttttaca tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa
    43681 caactacacc gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc
    43741 ccgtttttgg gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat
    43801 gagaaggttt tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg
    43861 gtttgtcatt tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg
    43921 taacagattc tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga
    43981 cttctagcgt atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt
    44041 gagcacttga ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa
    44101 agacaggcgt tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt
    44161 caatgatatt tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat
    44221 tattttgttc atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt
    44281 ccgaagacgg tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca
    44341 ctctttcctt ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga
    44401 tacttccatt ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag
    44461 actcgatcca atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt
    44521 cattccaata gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga
    44581 tctgctctct catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt
    44641 ctgtgtttcc tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg
    44701 tactgctatt gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt
    44761 cgaaagacaa actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga
    44821 atccattacc gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg
    44881 agtttttgat gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac
    44941 cgtcatctgc attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca
    45001 gtttggccgc aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac
    45061 agttcttgac taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga
    45121 tttggattcc tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc
    45181 cagaaatctg taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac
    45241 cccagtagtg actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac
    45301 gcttgttttc tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa
    45361 cgccttttgg aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg
    45421 tctgcccagc atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc
    45481 cgtttcctgc atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt
    45541 agtccactgt atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg
    45601 gcggatagtt tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt
    45661 ttgtctgata atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca
    45721 cctctcctgt tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca
    45781 tagtatgatc ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca
    45841 agcgagtagg tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga
    45901 ttccttctac cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt
    45961 catctgaagc gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg
    46021 tttcaggatc gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca
    46081 gtttagtaat cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat
    46141 aagaacctgt ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg
    46201 agacactccc aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc
    46261 gtgtccccaa tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc
    46321 tatccgagtc ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa
    46381 atgcctgccc aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt
    46441 cttgggcatt cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga
    46501 tgtctttggg gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt
    46561 ttccgccgtt attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc
    46621 tactagcact tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag
    46681 attgcttttt tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg
    46741 tatccatatc ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca
    46801 cgtgtgcatt ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa
    46861 ttaaaaccgg ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt
    46921 tttttaacaa gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct
    46981 aatttatttt tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa
    47041 aaatataact taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt
    47101 ttaaaataac gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta
    47161 ttattttgtg ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta
    47221 gtgtggactc aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg
    47281 catctttgaa aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca
    47341 cacagatatc tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac
    47401 ggatgtctag atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat
    47461 tttcctcttg ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac
    47521 ccgttcctat cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg
    47581 gatcatgcgc atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat
    47641 gagcagtcag ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct
    47701 ctgcaacaaa atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta
    47761 tacgagatgt ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat
    47821 aaattcgtca aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat
    47881 caaaaatggg atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca
    47941 agctaatgct tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa
    48001 tgtatcacct gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt
    48061 aaccatttca ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg
    48121 tcctgggttg tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat
    48181 aacgatgtca cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac
    48241 catgttcacg ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc
    48301 tataccggaa cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc
    48361 gcctgcgcgt tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc
    48421 ttccattgcg ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc
    48481 gattgctaaa aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa
    48541 agagttccat ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt
    48601 ctttttgctt tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt
    48661 ttctgctttt cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag
    48721 ttcgcttcgc gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt
    48781 caatagttcc cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt
    48841 catcgcttgt tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc
    48901 ttgtgctaaa ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc
    48961 atttgcaaaa cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata
    49021 gccagtttct tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg
    49081 atcgattttt ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt
    49141 gacaagaagc agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa
    49201 taccagttct ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc
    49261 aataattttt ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt
    49321 gttcagcata tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa
    49381 tttttctcaa aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat
    49441 agaaaatcct tctttagtcc gatactcttt atagtagtcc gtatgctaaa ataagtatgt
    49501 aatcgaataa cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga
    49561 taaaacgaaa ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca
    49621 atagtttttc ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac
    49681 tctttggttc gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac
    49741 ttgaaactca ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa
    49801 caatgaatca aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca
    49861 aacttaaagc aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag
    49921 aattggtgaa agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc
    49981 cgaatctagt tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca
    50041 aacagaccta tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa
    50101 tcgcacaaga ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat
    50161 ctgttgcgaa acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac
    50221 tcttttgttc ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact
    50281 ttttctaaag tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt
    50341 ttatggatca taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag
    50401 atttattgaa caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg
    50461 agattgatca gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg
    50521 aacgccaaga acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg
    50581 tcatcagcta cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga
    50641 atcatgtgca agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc
    50701 gtctccaaga agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg
    50761 tcttcgggaa ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg
    50821 cacaaattga caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata
    50881 atctgatgtt agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt
    50941 atatcgctgc tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga
    51001 tgaaaagagc agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc
    51061 aattcctaga tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga
    51121 tccagcaagc accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga
    51181 tccaagcatc tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga
    51241 ccttgcttcg tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg
    51301 acttattgaa gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa
    51361 atgaacgtgg aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa
    51421 caatccaaga gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag
    51481 tagagcttgg acacatggaa gaagatctga aacaaaaact gttggattta acccaataga
    51541 tcacctttcg cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg
    51601 gcgtttttct tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct
    51661 gtgtccatag ccatagccaa aataaatgat cagtccaata accattacga taccgaacac
    51721 gatccatgtc acagtttgca gacgaagcat caatacaata caagtcaaga tggagacgat
    51781 tggcaatagc ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt
    51841 tctcaacttc agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt
    51901 tagttccgct aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc
    51961 ggcataagtc gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg
    52021 aagtaagcca tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat
    52081 cgttaccgtc agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg
    52141 tcctacatac ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac
    52201 gattcctgtc aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc
    52261 aatgattcct cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac
    52321 ggcatcaaat cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa
    52381 accaaaaggc atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat
    52441 aaacaacgcg atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt
    52501 cttggcttca agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc
    52561 aatgtatgta ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc
    52621 taaacttttc aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc
    52681 tagtaaaaat tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac
    52741 aacatacaga taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa
    52801 acttagtcca gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg
    52861 accagcattt tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc
    52921 accaattcca agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg
    52981 attgagattg atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt
    53041 ggaaaacagc gattaaactg ttttcatata ccctaaaagg ataccaccta aaatgactaa
    53101 aaggcaacca acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa
    53161 aatcccacct aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa
    53221 accaagtgat ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca
    53281 gatcatgttt ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc
    53341 gcctaagatc attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca
    53401 gttgacgatg atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc
    53461 cttaccaaaa tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc
    53521 agtcaaatac gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt
    53581 cgtttgtgtc cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa
    53641 accagtagac aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc
    53701 attttgtcca acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt
    53761 gattacagga ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat
    53821 tcctagtgtt tgttgattgg catcgccacc aattttacca cttactaaac caatactacc
    53881 ccatgccaac atagggacta atgctattaa aatttccata accaatctcc ttttatttca
    53941 catgataaga aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa
    54001 cgattttcta acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg
    54061 tcccttttcc ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt
    54121 ttgctaaata aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag
    54181 taaatccctt atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt
    54241 taactgaaag gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat
    54301 ccggcgtata tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag
    54361 catcggtcaa aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa
    54421 aataatttgc ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga
    54481 tgaggtagtc ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt
    54541 catcgatttt tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact
    54601 cgatcgaacg aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg
    54661 agtcaatata atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt
    54721 gttcacggat cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac
    54781 cactcaaata attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc
    54841 ttctcttgct caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag
    54901 ctaaataagc aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga
    54961 tcgtcaatgc aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt
    55021 taaaaaaatt catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt
    55081 tgtttcgata tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt
    55141 gactgtcaat gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt
    55201 ttcccgactt aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt
    55261 tttgctcaaa tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt
    55321 aatgccattg tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag
    55381 taatgcattg atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc
    55441 tgcccccatg ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat
    55501 gatcggtact ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg
    55561 aagattaata tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg
    55621 attgaaatcg gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa
    55681 ttgtcgaatg atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat
    55741 ctttcttctt gctactacaa tatcaaagaa gcccttgtga aacaagttgg cttacctgga
    55801 aaatgtcatt ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc
    55861 tcttccaagc agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt
    55921 tttctttcgt tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag
    55981 cactagcaat atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg
    56041 ttctatcttt gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg
    56101 gtgagtgttc acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct
    56161 aattgctaat gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc
    56221 gagcatccga ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc
    56281 cgtaaagagt tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc
    56341 tcctccagtt ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc
    56401 attcgtttca tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat
    56461 catatgttgt tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa
    56521 aggatctttg acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt
    56581 cttttcatgc actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt
    56641 ttgataattc tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg
    56701 atatgtaaaa actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag
    56761 actgatttgg gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt
    56821 taaaaaaact gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata
    56881 cttcagactt cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc
    56941 cgattagtaa gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca
    57001 tattcggtac tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat
    57061 agcttccata agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac
    57121 cttctggcgc catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa
    57181 agtatccatt tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc
    57241 tatctgctcc tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt
    57301 cagaacggtc ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg
    57361 catcatattt ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt
    57421 cttcataatc aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat
    57481 catccgcttc tagttctgtg gaaaccttca aattatatgt gatcgttaaa tctcctccac
    57541 gtgcatctgc taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa
    57601 tcgtcacgac aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa
    57661 tcgtctcgcc ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg
    57721 tatctgtgat tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga
    57781 aataaggaat aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat
    57841 aagaaatcgt ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt
    57901 cctctacatt catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat
    57961 ctgtattgta tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca
    58021 tcatcactgg catcataaca accattggag acgcgattct ggaaatatga gctggcgaat
    58081 aagtttctaa gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga
    58141 cggtagagaa taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc
    58201 gatattttaa aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag
    58261 aattaagacc gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata
    58321 cttccgttac gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg
    58381 tagaaaccaa tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta
    58441 atgtaatcgt cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt
    58501 tcccgaaaat ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca
    58561 tttttttatt catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat
    58621 aaaagaattc ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac
    58681 cattttcctg attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt
    58741 tcttttacgg tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact
    58801 ttcccggatt ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct
    58861 tttgcatcca cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc
    58921 tcgtaacctt ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt
    58981 tgtcctgtcg taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc
    59041 aaaggatcat tgtctgctgg tttgatccat tgatttttca agtcattagc aggagccata
    59101 tctaaataat atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat
    59161 ggttttcctt tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt
    59221 agataaccga catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc
    59281 gggtgataaa ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc
    59341 aatccaactt ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg
    59401 tttttcttag gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc
    59461 ccagttgtta ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata
    59521 ttgtttctgt tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca
    59581 gctttttttt catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt
    59641 ggcaccgtct gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca
    59701 tcattttcat ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc
    59761 aacacgaatt ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg
    59821 actgctgcaa gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt
    59881 accttgctcc ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg
    59941 ccatgaagaa tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca
    60001 acggattttc aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa
    60061 gttcatattc taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg
    60121 aaatctcaac ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt
    60181 caggttcttc tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt
    60241 caggtgactt cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata
    60301 gggaagaatc gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac
    60361 tattttgttt ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa
    60421 ttttcaaaag ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac
    60481 catcgatgat ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt
    60541 caatgataaa cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat
    60601 acccatttgg tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt
    60661 ggtcgtaatt taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga
    60721 tcccaggcaa acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca
    60781 gcgggaagga agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc
    60841 cttcatggtc taattttcta actcggatct cccgataatc aaacgtattg taagcagtga
    60901 atgctaccca taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt
    60961 cacctgtttg cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg
    61021 tgtcattttc atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt
    61081 ctgcatagtt ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg
    61141 gatgaataac tttctcacca tccacgatta catatttccc gtcttcatct actgaataga
    61201 acgtgagtct ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg
    61261 gatatccgat ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga
    61321 ttggcatatt actgccttca attagtttat tgatattcat gtggattggc ttgaattcat
    61381 ttcgcatttc cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt
    61441 gtacaacaga aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg
    61501 gtccgccgac tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct
    61561 catcttcgtt ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat
    61621 aacgtggtgg tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat
    61681 ctcctaaaat cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg
    61741 tttcgattgg ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc
    61801 cagccaacgg ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt
    61861 cgtaacgaat ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat
    61921 cctccaggtt ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc
    61981 ccgcatcaag ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg
    62041 gagaaaattt ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt
    62101 ctggtggggc ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc
    62161 cgttttctcc tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg
    62221 gtgagacatt aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg
    62281 tagaagagat atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc
    62341 gcggtgttac gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag
    62401 catctagtcg ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac
    62461 ttggcgggtt ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg
    62521 cagatgactt ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac
    62581 caacccagtg agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat
    62641 ttacttcatc ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg
    62701 cattagaagt attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag
    62761 caatcttatc ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac
    62821 ttgactgaat cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt
    62881 tttctggatt tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa
    62941 gccctagtgt aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc
    63001 ccgtcaaacg attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt
    63061 tattgatagc tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg
    63121 ggtcagagag cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag
    63181 tttgactatt ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa
    63241 cgatatcgat tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt
    63301 aaagggttgt tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt
    63361 ctacccattt tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt
    63421 catttcccca aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg
    63481 atccattatt agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac
    63541 tatcatcgat caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat
    63601 tgctttgtgt ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcatctatt
    63661 ctttcatcaa ccaccacttg aagaggtagt tacccttcgt tcacatcggg gatcttttct
    63721 gtttcaaaaa tcaatgtgcc ggtttctgct tcttttgaat aaacttttcc gacataccat
    63781 tcttgaccat cgatcgtctc gacttttagg tcttctccat cttcatcata ggaggataga
    63841 cctgttccac gaacgttttt tacggtacca atcccggcgg ctgccgcatc gattgctaaa
    63901 cgtattctac cttcattggc actttccttt ttttcaaaag ccagatgcca ttcaagggtt
    63961 tcttcttttt caatatactt cccttcaatt tttgcatagt cctcatctaa gaatacctca
    64021 tcctcctttg tttctgttga ctcagcagct acatccaggg tcgtcatatg atagactgac
    64081 tggaaatatg gtccaaatag caaactgaca gttactaact gcaaaagctt caattttaac
    64141 cctttcacat ccttatactc ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa
    64201 acaatgccca tctaattata atttaattta attttaattt taaatcaaat gatatccttt
    64261 ttagttaaaa aacaccaatt atacaacatt tattattaaa attaaattat aaaattttat
    64321 aacgttctca tttaacaaaa cttaagttat taagacaaat gaataaacaa ctacgctttc
    64381 ctcgaaacaa aaaaataaag cacaaatgcg catttacgca ctcatgcttt attcgtacaa
    64441 ttaattcaga taacggcagc gcataggatg ccaataacac ttcctaaaat agctcctcct
    64501 aaaatgtcag taggataatg taaaagtaaa aaaatcctcg aataagcgat caaacaagca
    64561 aataaaaagg ctaatattcc tgcaactgga cttaattcga acaacgcagc tactgataaa
    64621 aaggctagcg ctgtatgtcc tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg
    64681 acaagccgac gatttttttc ataaggtctt ttccgtcttg tcgttttttt gataaaaagc
    64741 aaaccaacaa aaaaatagat caaactgccg ataagaatgg ctagaccata ttctctagta
    64801 tcaggtatca agactaaaac agcagcaagg agcaaccaaa taaaaccacc attagagata
    64861 ttactgataa atttcaaaaa attgattttt cgactatccg ttttccgttg cttggcgaac
    64921 ttgttgataa tactatcatc gattttagca atcaaacgca acatgttatt cctccttttt
    64981 aagaaccttt tcttgcgtac gatggataaa aagcaggact tgaaaataaa acaagaaact
    65041 gaaacctaat aaagcaaaat agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa
    65101 cgtgcctgcc aaatagaaaa gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt
    65161 aatccaagaa gcttcttttt gttccagttg aagcaagatt ttgtaactaa agagaagcgc
    65221 gcttaataga agcaaaaaca acgtagtata catcaatgta tagccaattc ccccacccca
    65281 atagcggaaa atctgataat cgatcaatag aagaagaaaa taaacacttg ctaaactatc
    65341 ttgctttcca taaaaagaga agttctcacg aaactttttc cagaatagtg aaccgagctt
    65401 tttctcttca ttttttttgt aatgataaat catatacaga actgttcgac ttgcagttcc
    65461 taatgtgaaa acaggcaaga cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg
    65521 aatccattca atgatttcta agaaataatc attggctttt ttaccaatcg atcgattcat
    65581 catccttttg aacctcctgt caaatccatc ccttcaatga aataacgttg tgcaaaaaag
    65641 aacagcaaaa tcgtcgggat caagacaagt gttgctcctg ccatcagata attccattgt
    65701 gtcgttgctt ggttctgaaa aacttgcaag ccaatctgta acgtgtattt ttcttgatct
    65761 tggatatata acagaggacc taagaaatca ttccaagctg cgttgaagga attgatcgca
    65821 atggtaatca aggcaggttt cgtcaatgga agcatcaaat gactccaaat atacaaatga
    65881 ttcgctccgt cgatttcagc agcttcgatc aattcattat tgatcgataa gtaaaattga
    65941 cgcatcagaa atatattgaa cgcattgccg aagaacgatg gaacgatcag gggcaaataa
    66001 gtacctaccc agccgatctt ggagaataat acatattgag ggatcatcgt tacaaacccc
    66061 gggatcatca tcgtagaaag aaccaaagca aacatcagct ttttcccagg aaaatcaagc
    66121 ttcgcaaatc cataagcaat aaaagaattt gaaaggacat taccgatcac tactagcaca
    66181 gtgatgaata atgtatttct tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga
    66241 tagttttccc atacgatttt ttctgggaaa aaggtcggag gataacgaac gatttcttcc
    66301 attggtttca atgaagtaaa caccatccaa agcaatggaa tgatcaaaat gattcctatt
    66361 actgtcatga ggacataact tagtattttt tttgtttgcc gattcacact ggtctttttg
    66421 aaataatcca tcatttgccg tcacctccag aataatagac ccacttaggt gcaagcttca
    66481 aattgacaaa cgtcagaacc aacacgatca gaaacaggat cattgacata gccatcgcat
    66541 aacccatatc aaaagctacg aacgccttgt tccacatatg cagattataa aaaagcaaag
    66601 aatttgcagg tccgcctgtt ccatttttcg tcatgacata agcttcttga aaaatttgga
    66661 aagaaccgat cgtagaggtg atcacatcgt aaaaaataat aggagtgatt aatggcaaag
    66721 taatactttt gaactttccc caaacgcctg ctccatcgat ttctgctgat tcatataaag
    66781 atctaggaac attttgtaat gtagctaagt aaagtagcat tgctcctcca gaactccata
    66841 ttttcatcaa aatcaacgca ggtttcgtcc attgtggatc aaacagccaa gctggtccag
    66901 ggatatggaa ccagcccaga aatgtgttga tcaatcctgc agatggagaa agcagctgca
    66961 tccataagat gtagactgct actcctgata agactgccgg taaatagaaa gctgtacgga
    67021 atacactgat tcctttgatt ttttgattga gtactgtggc taaaaacaca ctgaaaatcg
    67081 tcgtcagcgg tacattgaag atgacgaaat aaacggtgtt gtataacgat ttccaaaata
    67141 aatcatcgtg aacgaacatt cttttgaaat ttgctagacc aatgaaattc atcttggatg
    67201 tcaaattata atcggtgaaa ctaccaataa ctgaaaaaag cataggccct agcataaata
    67261 ccaagaaccc gataataaaa ggcgagataa ataaataggc ccatcttgct tcttttttct
    67321 ttcggataga taaacgcttc aaattttctt gcctcctctg tacctagaca gtcaaaaatg
    67381 gattattgat tttgcttgac taagttttct actgcttttt gtgcatctgc caatccttct
    67441 tttggtgatt ttgttcctaa aagaatctgg tcaatctgtt cattcactaa tgtcgtgtaa
    67501 tccggagcat ctaaaggaac tggtgtgatc accgtatttt taaagttttc gtccgccatt
    67561 tgatagatca tttttccttt atccgttagg ttgtcattat tcactaaatt ctcattggct
    67621 gtcttgctcg ccatgatatc aaaacttttt tcgccgaatt tttcttgtac ttctggagaa
    67681 gaaagatatt tgatgaattc ataagaggcc tcaggatctt ttgctccgta tggtacttcc
    67741 aagacgaatc cgccacccca cgaccaatgg cctgaacctt cttctttttc tgggagctgc
    67801 atcacgccaa aatcaaaatc atccggtgca ttttccatca aactagagta ataattgata
    67861 ttttgggcac gcatggctac taatccggaa ataaatggat cagatacacc agacccaaat
    67921 tcggcttcta atttattgat cgtatttttc ccataataat cttgccagtc ttggatccac
    67981 tccaaggctt ccactttatt tttagtatca atcttgactt tttcatcttt gtcaaaccaa
    68041 ctagtcccgt tatctgcgtt tagcgcccat acatcagccc ctaaattcca taatggataa
    68101 aaaccgatgc gtgtaaattc ttttccttct tttttatcta gtttacgtgc tgtttcttct
    68161 aattcatccc aagttgtcgg tagatcttgt tcactgattc cagcttcttt aaataacttt
    68221 ttattataaa aaatgacttg tgtatctgta ttgaatggga tcgcataagg atcaccttca
    68281 tattctactg tatcccaaag ctgcggataa aaatccttag aagtgtcttt ttctacatat
    68341 ttggagagat tagttgcttg ctgtgcttct gctctttggg caacggaatt tatgtcctgt
    68401 acaataacat cgggtgcatt tccagctgtt attgcagata aagatttagt ccagatgtca
    68461 ccccatggct gatacttata atttacatgg atctcgtttt gtgattgatt gaaatcctca
    68521 atgatttctt cgatagcttc ttttcgtgca ccggatcccc aaaaggacca gaaatcaata
    68581 ttttttcttc catcacttgt tttttcagaa gaatttgctg cacttgaact ggcatcgctt
    68641 gcattacttg atccgcatcc tcctaataaa aacaatgctg aacttgccag caaccctgta
    68701 aacaataatt ttttcatatt ttacctccaa attttaatgt aaccgatgcc ggttttaata
    68761 taacgatatc attttgttct gaaaataaca atttataagg tatgattcta aaaaaattat
    68821 taatgatacc aatactttat ataattcgcg agcgctttct ttgaattttt taatctttcg
    68881 tagcagaatg agaatgtatt aaaaatagat taggaggaat tttgatgttt agacaccaga
    68941 aagaattgca gtttgaagca aaaccagatc gtccgaatcc attaatcgcg aaatatctgc
    69001 aggagctgat cggcggccaa tatggcgaga tgagtgtagc tatgcagtac ctgttccaag
    69061 gctggagctg ccgaggagaa gaaaaatata aagatatgct gatggacatt gcaacagaag
    69121 aaatcggcca cgtggaaatg ttggcgacaa tggttgctcg tttattagag ggtgcgcctg
    69181 ttgaagatca agaagcagcg atgcaaaaag atccaacaat cggtgccatt atctctggaa
    69241 tgaatccaca gcacgcgatc gtagctggct taggacctcg tcctgctgac agcgtgggca
    69301 atccatggag cggtgcctat atcattgcga gtggcaactt gttagcagac tttagagcta
    69361 atttaaatgc cgaatcacaa ggaagacttc aagtagcacg tatttacgaa atgatcgatg
    69421 atcgtggcgt aaaagatatg ctgtctgttc tccttgcaag agatagctat catcaaaatc
    69481 tatgggaatg tgcagtgaaa gaattagaag aaaaagaagg ttcaatctta gtcccaagta
    69541 ctttcccgcg tgacaaagaa cgaaaagaca ttgcttatga cttctataac ttctcagagg
    69601 gagaccaaag tagtgaaggt tcttgggcta gtggcaaagc actggatggc gaaggcgaat
    69661 atcaatggtt gaaagaacct aagatcgaag gcgctgcacc aaaattagaa ccagtaacac
    69721 caaaaatgta tgggacacct ccattcaaga aataaatatc tacccgtaga aacacccgtt
    69781 ttttgttcca cacgctttgt gagcaaaact gactaaagtc attaatcata accacccttc
    69841 aaaagggtgg ttttctctag agctataagc tcaaatcacc ggccagcgcc taaagacgct
    69901 ggctttcata ttttatgttc aagccatatt gcctttgcca gttttgccca cctcttaaaa
    69961 ggtttatgta ctactcctta gcccttaaaa ggatcgtctt actctcgtac actcagctta
    70021 tctaacgcac tatcatgttt ttcttgttct tgaatgtact ttttgatggt cgcttcattt
    70081 tgtcctactt ttgtcacata gtatccttcc acccaaaagt gtcgataccc aaatttatat
    70141 tttagatttg cacaatctct tgatgatctc ctgaatattg gctcgatatt gattataaat
    70201 tatttttctt ctatactttg gtgtgaatac aatgtggtat ttacacatct actttgtacg
    70261 ggctaaacta tttcccttta ttgctccacc cgcatagcaa gtggttttgt atttcaatcg
    70321 ctcggcgcgc tcaattaggt ctaaagacaa taaatctaaa aacccgctgc ttcactgaca
    70381 gaaacaacgg gttttcagaa aaaaatgaaa tgaaaaagat ctcttacggc aatctatttt
    70441 atttttttga ttttttataa atggaaaatg cttcaagaag tccaagaaat aaagccgtat
    70501 aaaaacaaga acctatgaaa tctttattta ttagatattc aacagaaatc ccgataacac
    70561 tagccaacaa tatatttatc agaagtgtaa aataaggatg ctttttatag aatagaacta
    70621 gtgttgtttt catagactct cctttcttca tatttccaat taatcacaaa ttcacggcat
    70681 tactagaaaa attaaagggg cgcagaagtg gaaaaatact cttcgacttt ccctacaaac
    70741 caggccatct tgtgtttaat aactatacca aatctaaggt acctctaaat ctaaattcca
    70801 tttgtggcgg tgacctccaa tttttaactc ttctatctcc catccagtat acataacctt
    70861 gatacttcga ccacttatat atcgaacaca caaataccta tccattgcag gagtactacc
    70921 taacttagtt gctacttgca tctaaataac agctgaaaag ataggactta ctcttagtaa
    70981 agtatctgaa ctattaattt ttaaactatc atttttatcc tcaactacat gcacatctgt
    71041 tgcaacttca ctttctgtct catccagata aatgattaag gaatcgggaa ttgcaatatc
    71101 ttcagctgac gctggaatag ttgagctaaa ttagtcatca tatctttatt ataaaataac
    71161 caacagcaaa aaatacaatg aaaaacaaac ttggaactaa tgtatcatta ataaatgttg
    71221 aaaaattcag caactcatta ctgtatgatt ttagcagccc aaccaacata taccctataa
    71281 aagctaataa gatggttagg aatcctttag aatttttact cattcataga cacttcctta
    71341 aataactttt attatagaag gtattgtaaa taataatatt gacaaaaagt gactcaaaat
    71401 aaaaaaaaac ttacattata ctggaatgaa ctgtattgat agtgtaccta aaagctctac
    71461 tgacataaga tcgtgtaatc ggtaaagtaa ttttattaat tatacgggat gtaatcaatt
    71521 agagaataaa ctaatcataa aaggtacttt tacattcata attgtcgctt tgagattcta
    71581 ctttggttca ctatctgacc caattgcaca ttttcgatca ttacaagtat tggtgtcgtt
    71641 agaacaacta aataaaaact agcggtagat ttttcagaat ctatgctaat ttctgtatgg
    71701 atgttccagt gatggcaaat ttctcttttc attgtttttc ttgtcgcatg atatgccttt
    71761 ttgtgttatt cagttaaact atagaaattc tttcctagac agatcttgat cccaaatttt
    71821 acgtttttga gcatcgatat agtttaaaat gacattactc atatctaaag agtttagatt
    71881 ttttaggact aaaactgtca gttgttcttt ttcttctttc tgttaaagta ttgtcgcgac
    71941 ttttcgtata cgttaagata tgtcgtgaaa aaacaagttt tgtgacacaa aaaaacgaat
    72001 gacttgagga aatcacctca atcattcgtt taaaatgcta tatattcttt agtttaagat
    72061 acggaaatta atgccatcga ccacactagt agaatgaacg acatttactt ggcctttttt
    72121 taatttcgtt atgtttagca tataaaaata ttatagagtt tacttacaat gcttaaaaca
    72181 tatactgtat aatctgatca attttagcca tgtcttgcaa tggtaagttt tctatttttt
    72241 tgagttttcg ttccttaaaa tcaagagatt ttaattgtgt aataattact tgtcctttta
    72301 tatctagctc ttcaggtaat gagtaacgtg tcggtaaatt ctttatagtg gaagtaattg
    72361 gacatatgac cgaaaacatt gttttacggt taaattcata acgagagacg actagtcctg
    72421 gtcgtctttt ttgaatttct tttcctacgg agggatcaaa atcaatccat acaatatcac
    72481 cttttttagg aatataaatt ctttcttctg acactataaa atttctctcc cttcaggagt
    72541 taaatcttcc cattcgtctt tctcataata ctcggcctct tccccaccac taaatggatc
    72601 ttcaattttt ggaactaacg taattgttcc atcatcagaa tacacaacga tatattcttg
    72661 gttttctgaa ggtttctttc cgttatcaga aggtaaagtt accactacag aacttccttg
    72721 taatctagat tttgtaacaa gcattatcat cactccctta ataaaagtat actatataac
    72781 actaagtaac gcaaaattcc cctttgtaaa ctatctagaa aattgttttg tttaaagtat
    72841 atcttattgg atataaatag aaataaattg tagccagttc atttttcttt aactaaaaaa
    72901 ataatccaag aaacattgaa cctatggatc caaaagctac ccaaatacta tagctaaccc
    72961 cccgctacct tcaattttgc agataaaacg ctttgggaga aaatttcaaa gacaacaggc
    73021 catcctatca tgcccgatta taaacaaaaa gctggctatt ccttttgctc tgacaaattt
    73081 caattgggaa agttcacgaa actagcaggt gaagaagttt caactgttcg gatcaaagaa
    73141 tgcccgcttc aaatagaaac attggttcaa cgaatttcaa ctagacaaga ctttgctatt
    73201 gtagaacgtg agatcgtagc tatttttgta gaagaaggga ttttacatga tccaactcat
    73261 atcaatgtgg ataaatggca acctcttatc tataaattca gagaatatac aactgccaac
    73321 cagtcgttaa ctttgaattt tagattccaa gaattcaaag agtcataatg ataaacatcg
    73381 ttaggtataa ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag ctatacatta
    73441 gaaaggtcga ctgtgaccct atagatgcag tatatgcagc ttatgagcat ttcttctgtt
    73501 ctctttgttt ttgggatctg tgctgaagtc tttttcgttt tttgccgctc tttctttgaa
    73561 aaatcgatta tgttatacct tctccattac taattcaggc atctgctgag taatgatttt
    73621 tcgcgcaaaa gaaatatctg ttacccaagg ttcgatttgt tcttcagtca agacaagcgg
    73681 cattcggtca tggattggtg cgactgtgcg gttaggttca gtagtcatta tgattgattc
    73741 tgccattttt tcatcctgat ggctacgata aaaaccgcca atatacacta ttttttcctt
    73801 atttgaaaac ataaatttgt ctttttcttc attccactca ttgggaaaac acaacgattt
    73861 tgcaaaaatg gttgatgaaa ggtctttttt tcttctactg tctctgcacg ggcattaatc
    73921 atcaattgtc cttttttaaa tccggtaaat ccccacttca tgatttccgg agtgaggatg
    73981 ttttcttcct cttttcttaa cgtcacaaca agatttgacg gaaaaacttc tccagctgct
    74041 aattctgctg cctgcttcgg ttgtttcgtc tgggcttctc gataataatt ctgaaggagc
    74101 tctgactcta gatcaaaaaa ataacgacca cacatcctaa tccctcccaa tctttttttc
    74161 tatcatacac tgcaacaaga agttcgcacc aacaaaacac tttcaatttt tgtagaacta
    74221 aaaaagttgt gacaagtgac aaactctcca gtgaatggta ttctcctgcc aactcctcgg
    74281 tcacaagtca caatattcaa caaacatgag aagctgcttt ttgaaattgt tccttgtgac
    74341 tcggagtgaa acggcaggct tacgacctct gggtaaacgg tgttcaaaag ccagtttctc
    74401 ggtattaagc caaatttatg caaaaatgta gaaagctatt ttcacaaaat ttttcttaat
    74461 actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat
    74521 ctgcggtaat aagcccaacc aaacgaaaaa tatgagcagc tatttttatt tggctgttct
    74581 tattacttga tgcagggcag ctttttcaca acctctccac taaacgatgt tcaatcagct
    74641 aaccttcggt attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc
    74701 tctaatactc aggtcaaagc gctgatttca caacctctaa tacacggtgt tccagaagta
    74761 gcttcttcga aaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc
    74821 cttcttattt cttgaagctg accacttctg tcacaacctc taattattaa agaacctttt
    74881 gcgaagttaa caatctttct ttgaccaatt gaaaattctg cctaagtagt gatagatcct
    74941 gtgtgacttt caacaataag atacttccct ggatttcagc aatcaacgct ttggcttgac
    75001 ggtctgcttc ttcatcggac agtttttctt cagaaagtgc caggatattt tgtttcgtat
    75061 acttgaccca ttgattgact aattctagta gcaacagacg gtattcttca tccactgtac
    75121 tcaactcaat aatcaaatta cctacaggac agccatgata agtgatctgt gtctcatgat
    75181 cagcgaaaat ccagtccaac atttcttcta atgcttcttc tggctgtttt ccagcattta
    75241 agatgtcttc gaacaattct gtctgccata cgtccatatg cgcatggatc accgctagac
    75301 aaacttcttt ttttgaagaa aagtaataat aaaattgacc ttttcctgta tcagaagctg
    75361 ctagaatatc tcggattgac gtttcatgat agcctttttt ataaataaga tctttggtcg
    75421 cttccaagat cttttccttt gttttcaatg atattctcct ttttcatttc tcatagtcct
    75481 atattataca gtaaattcat cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa
    75541 ttatctgaca cagccctcac tataaaactg ttctcatata gctagatgtt cattgattca
    75601 agaactgcga ggacaaaagc aattcctatc ttatgatagt tgctctaata cttcctctgt
    75661 tgtcatcact tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg
    75721 gccaggagca ccaattgcat ctgtcgctac cacaacattg aatccactct ctaccaattc
    75781 acgcatatgg gaatcgctac acaagtttcc gttcattcca ccaagaatta ctgtgtcgat
    75841 tccatttttt ctcaattgga gcgccaaatc attgctttct ggtccaaaga ttttatgagg
    75901 agagctgatg atcgtatttt catccaaata aggtttcaat tcttcgataa aatcggctcc
    75961 tgaaccttct tccactgatt catattgact ttttctagca aacatctgct gctcaagcat
    76021 catatgttct cctgcaccgc caaattgcca tttatggtca tgtgggtaaa aataatgagg
    76081 agaaataaag agtttgtatc ctttttcttt tgcttgtttt accatttcaa tcatattttc
    76141 gatcgtattg tatttttcta agatatcttt tgtcaaacca aagccaccgc ctgctggttt
    76201 caagaactcg acttgcgggt cagtgagaac tactgctgta tttttattat tgaacatggt
    76261 ggattctcca ttcgttattt attttaatac atcatttaga gcttcactca ttgtcggatg
    76321 agaatagatt tgatctctca ataacgtata aggaagtttt ccattcatag ctagcgaaat
    76381 caagttgatg acttcatgag aatcttccgc atagatactt gcccctagaa tcaagtcagt
    76441 ttcagggtcg actaaaactt tgaatacacc tttaggatct tctaatactt gtgctttagg
    76501 gacaccgctt gtcatatact tgaataattt gtaattgacg ccttgtgctt tggcttgttt
    76561 ttctgttaaa cctacattgg ataaagtcgg agtgataaat acactgtaag gcacagcttt
    76621 ccggttattc gttgttcgtt tattctcgcc cttcaactga tccataatga ttcgataatc
    76681 atctagagag atataagtga actgcaatcc gcctttgacg tctccaatcg cccaaatgtt
    76741 gtctgcatct gtacgaaggt attcatccac agcgattgct ccgcgatctg ttagtttaac
    76801 atctgtattt tctaatccaa gtgatgctgt acttggtttt cttccagttg cagccaaaac
    76861 ttttgacgct tggattgtta cttcttggcc atcttctgta aaggtgacgg cagctgttga
    76921 ttcttggtct gctacttgat ctacagatac acctagatgg aattcgattc ccgcatttgt
    76981 catgtcttct aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa attcagaatg
    77041 ggcatcaaga acgacaactt tagatccgta ttcattgaac attgatgcaa attccaagcc
    77101 aatatatcca gccccgatga tcactaattt ttccggtaat tgttcctgat ccatcgcttg
    77161 cgtagaatca atcaagtagc gacttgtatt caatcctttg attggtaaaa tgattggttc
    77221 agaaccagta ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac cattattcgt
    77281 cacttcgatt tgatggttag aaagaaaacg tgctgtaccg tccatcactg tcccagttgc
    77341 ctcatcgctg atcatatgat aatttttggc gcgaagcatg cccgtcaatt tttctttccg
    77401 agcaacagcc tctgtaaagt cgattcctct ttctccattg aaaatcaatg atttagaagg
    77461 aatacagccg atgttgatac atgttccgcc atacatacgt gttgactttt caacgactaa
    77521 aaccgattca ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc
    77581 gatcacaata ttttgatatt tttccatcat ttttccctcg cttctttttt acctaccgat
    77641 tggtacaaaa atatgataac cgataattgt ctattctcca aatcatctgc tttatttgtc
    77701 aaaaaaaacc agacaaaaag cggtcctttc acgtttttag tctggttcga tttcctttat
    77761 tcttctaaac aatcgttact tctacatcga tatttcctct agttgctttg gagtaagggc
    77821 agaattcatg cgcatcttct gcaatttttt gggcttcttc ttcgctgatg ccatcgatat
    77881 gcacttcgaa tactacaccg atctgatagc cgccatcatc taaattataa agagagacac
    77941 gtgcttttac tgtggactct gctgtcattc ctgcttcttt gatcatatgt tgtaccgccc
    78001 cattgaaaca agaagcataa cctgctgcaa ataattgttc tggatttgtt ccttctgcat
    78061 ggattcctgg aggagtgatt ttcatatgca tcgagccatt tggttcctcg acttctccat
    78121 tgcgcccgcc atggttgatc attgctgttt cgtatgcttt tttcattgta ctgctccttt
    78181 cgattgacca tttgctactt ggctataatt atagtgtatg acaagtaagg cgctttctac
    78241 aaaaattctg cttattcgaa taccagaatg ccgtcttcta ctatttttcc aaaaaacaaa
    78301 aaaatactac tcgtgaacaa cagcgtcata tttgttccaa aataaatagc aatcttttct
    78361 acataatctt ttatatgatt gattttaaga tacatatata ccagaaagtt gaccccataa
    78421 accaatactg ttaaaaaaat aaccatattc gttaccattt tttcctcctt ttgctggtct
    78481 ccctaccagc actcgattta accataccac tttttttgcc gtccaagcaa ctagcctttc
    78541 aaaaagactg gtttattctg ctgttaatga ttcaagatca gaaaaatgtc cgaataattt
    78601 tgctaatttt actaacgcca acttgttctt tccgaattca tcattttcta tctgtaatac
    78661 tagtaacggc tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt atggctcttc
    78721 tagatcatat cgaatacctt cttcattttc cgggtcgaag ttcatccctt tttcttcttc
    78781 caacagtcgc ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt catcgctgaa
    78841 caattttaat cggatttctt gtacttctac gggctgtttc aactctttga tttgttcatc
    78901 taatgtgata ccttttcttt ttaattctgg caaaagcatc aggatctttg cgatgacata
    78961 tgcaccatca tccagaaaat agttttcctt gaatgcagcg tgtccgcttg tttcgatggc
    79021 tagctgtgta tctttcccaa gacggttaag ttctaatgct ttattgatta catttcgata
    79081 gccggaaata taacgaactt ggatgcctcc tttttcttca atgaatcttt gtagatgaga
    79141 agaagtaggg gaattcgtca cgattcttgt tcctggatgc tcttttaata cgattgtact
    79201 taatactgcg atcaaattat ttcgattgat cactgttcca gaagcactga caactgcaga
    79261 acgatccaca tctgtatcga aaatgatccc aagatctgct tcatttgcta aaacagcctg
    79321 cttgatactt tccatcgctt ctttattatc aggatttggg atatgattag gaaatcggcc
    79381 atctggttcc aaaaattggg aacctgttga atccgcacct aagctattca atactttttc
    79441 agcaaagaat ccaccagcac catttccggc atcaacaatg attttccaac catttagtgg
    79501 tttgctttct agtgttccaa tccccttttt aatttttgtg actaaatctt gcgcataagg
    79561 tgtcaaaagg tctgcttttt ctacgcttcc agtttgttcg ctttttattt tttgctgctg
    79621 tgataggata aaagcaatat cttctttttc tgctcctcct tctgaggtaa agaattttat
    79681 tccattataa taatagggaa gatggctagc agtcagcata accgcagcat cgcacgagaa
    79741 ctgttcaaat tgagtggaca taaacatagc aggcgtagta gctaattcga aatcgatgac
    79801 atgtatccct tgttctttca gactttggat caacgcctct ttcagtgctg gtccgcttat
    79861 cctactgtca tgaccaatcc caatcgtcca ttttttattt ggatcggttg atttcttctt
    79921 tttctttatc cagtttgcta gtccccagcc gatctttttt accatgtctg tcgtcaagtt
    79981 tacttcatat ccttcaactg gtaatgcgat tcctcgaata tccgatccat tttgcagcgc
    80041 tttcatatct ttcatataaa agtcctcctc atttattccc tcattttttc cagcttttct
    80101 gcaaatcgct gtgcttcttc ttctgagcgg caaataataa tgaatgtatc tacaccggcc
    80161 atcgttccga caacttcagg gtaagccact tcatctagcc aattcgttac cacatcggca
    80221 ccatttcgtt cagtcaatac gataaccatg aactgaacag actggatacg caaaacctcg
    80281 cgtctaattg ctgtacgcaa acgttcttca tttaaagaaa cagatggctg gttaaataat
    80341 gtatagcgta ctattttgtt ttcattttga ctttttacta acttcatttc tcgaatgtct
    80401 cgagaaatcg ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc aagcagctct
    80461 tcctgtgtcc caataggttg ttctgtaatg atctggcgga tcagtgcttg tcgctgtttc
    80521 tttttcatat tagacacctc tcaatgttga ttatagcaaa agataagtaa tatttcttca
    80581 tattttggta ttttttactt ttattttttg ttttcattca ggttgctaac ctttttctat
    80641 tttaacacgc aaaatcgtct tcattttttc aggtgctgat tttcttggat cgctgatgta
    80701 aatctctttg tgttctttag aagctctttc atagccttct tttgcgatga atgcttctaa
    80761 tttctcaaac gttgctggtt cttcggcata gggcccgacg tgtaagattt gggcacaaag
    80821 accttcttcc atctttttga atactacttg ttctttcaag tcttccggaa gtttgctaga
    80881 acgctgaatg gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc ggatcatcaa
    80941 ttgataagaa aaatgttctt ttttcatcac tggttcatgc aaatactttt cttgcagtcc
    81001 ccattgtcct tccagtggat agacagtata catctgataa tcaggaatca gccaattttt
    81061 tttaggcgac atgcgtattg catagctgac tgcatataga caggctactc ttcgtttaaa
    81121 gtcttcctga ttcgggtcgc cgatccctct gatgctaaag aatgattttt taggaacctc
    81181 tagtatttgc gggctttttt tcatactata gctcttgtct ttacgccatt caattttttc
    81241 catttttctt cctccgcgaa attccattta gttatttatt atcatacctc tttttgagtg
    81301 acttggctaa tcgtgttgac actatttttc agtttgtgct agaataagtg aagtaaataa
    81361 atcgtacaga taacacgttt cggcgtgtcg agagagaggc ggtttctatt tttataatag
    81421 aaatcactct ctttttttac gaaatttttt agaggtgatg taaatgacaa aacaaaaaca
    81481 gctgctttta gtacctgcag taattgcaac agggatgatg tcttttgcgg gcgtattgat
    81541 cgagacggcc atgaatgtaa ctttcccaac tcttatcaga cagtttgatt taacgactgc
    81601 acaagtccaa tgggtaacaa cgatttatct tttgatgatt tcgatcattg ttccgctgtc
    81661 tacttatttg aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa atctgctttt
    81721 cttggcaggt ataatgatcg atttcttctc tcctaccttc atggtcctat tgtttggtcg
    81781 attgctccaa ggtgcagcga caggtatcgc tcttccgttg atgttccata ttatcttgac
    81841 atttgccccc ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga caacggccat
    81901 tgctccagca attggcccca cttatggagg cattatgact tcacatttta catggaatca
    81961 tatcttcctg tttcttgtgc ccgttttgat tctttctttg attatcggct ggtttgctat
    82021 tcccgagatg gcagtacaaa aaagtggtta tttggattgg ataagcgttt taggaatttg
    82081 tcttttgttt agtggaagtc taacattttt gagtacgttg ggaacagttt ccagctggat
    82141 tgctttaatc atcggcggta ttggctggtt ccttttttac tatcgaagta aaaaagtgga
    82201 gcatccactg atccgactgt ctattctttc aaataaaaca ttccgcttgt ttttgattgg
    82261 cttcttagtt tatcagtttt tattacttgg tgtatctttt gtcttgccga atttccttca
    82321 gatcgttcaa ggaagtagtc cttttgtcgc tggattagcg atgcttcccg gcgcagcggt
    82381 tggtgctttg ctttctcctt tttccgggaa aatgctggat caatatggtc cgaagaagcc
    82441 aatttttgct gggctgattc tttctttgat tggttggcta gcattattcc tactcatagg
    82501 acacgcttca gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg gtatcggatt
    82561 atcttacagc aatatgatga ccaccggaat gaatgcactg aatgaagaac tacaaggaga
    82621 cgggaacgca atgttcaata ccttgcagca gttttctggc gctgtggcta cttcattagt
    82681 agcggtcatt atcaattacg tccagcatca tacttcccat aactatgaag tgtctactac
    82741 attaggatca aaagcagcat taggcgtctt gttgctgttg cttctcgtaa gctttgctcg
    82801 attcgcctat tatctgttct ttgctaaaaa agcgtagatt ccatatacgg caggtgttgc
    82861 atctgccgtt tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt tatggaaaaa
    82921 attgccatta tcggtggcgg gatcattggt atgaccctag ccagttactt agatacatca
    82981 aaattcaatg ttgctttatt tgatgaaggg acaggacagg caactaaagc tagcgctggg
    83041 attatctccc cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct ggctaaagac
    83101 ggcgctgctt ttttccctaa acttataaaa gatttccaac ttgatcaaac gatttacgca
    83161 caatcaggga cacttttgct tcgacctgaa aaagatttag ctgaattggc tgttcttgcc
    83221 gagaaacgaa aagaagaagc gccagaaatt ggaaacatcg aatggctttc acctgaacag
    83281 acatctcaag cacttccgtt attgaaacca gcagtttcac tgcgtatcag tggtggtggt
    83341 cgtctggatg gaaaagcata tttagaacat cttggtcagc gtttagcaca aaaacaaatg
    83401 gagcagatcc aggcaaaagt cactttgcat aagaagagcg attcttggct catcaaggga
    83461 ccgtttggag aatacacagc tgatcgtgta attttgacac ctggcccggc acttaagcct
    83521 ttattacaag aattaggcta tgctgcagat atacgtccgc aaaaagggca gctcttagca
    83581 tttcagacat cttataagat gagtcaagac tggcctgttg ctatgcttga cggagaagct
    83641 gatttcattc ctttcatgga tggaaagatc cttttaggtg ctacccatga aaacgatcaa
    83701 ggctgggatt tggctcctac tagcgaagct tataagggat tgactaagag tacagaacag
    83761 ttcttgactg atccagatca gataaaaaac tggccatacg agttccgtgt aggtacccgt
    83821 gcttatacgt cagatttttc cccatttttc ggcgtactgc cagatgatcc aagcttactg
    83881 gctgctagcg gtctaggctc ttctggcttg accacaggtc cttatatcgg ctatctatta
    83941 gccaacttct taaatactgg tcattggcct acggaagatt atcaaaagga catctccacc
    84001 tatattacga aaaatccatc atagaaaaac agctttttca agtaaggatc ccgagcgata
    84061 ttgcgcatgg attacttctt gaaaaagctg ttattttagt tcaatttctg aatcaaattc
    84121 tccaaacttt cttttgcttc atctggcaag agatcttttc ctatctgagc ttcaatgaat
    84181 cgtaaacgaa tatcaagtcg ttgtttcacc agatttttat aggacgtatc ctcaaaagaa
    84241 acaggaaaat ctggtatagg taaatagtgg atgtcttcaa atggaccaaa cgacttgaat
    84301 tctgccgttt gttgcacgat tctttcaacg attgacaatg tcgtttcagg tttgattttt
    84361 ttatcatcga aatatccagt attcaggaca tagcaggctg tttgctgttt caaaaacaac
    84421 tctcgaaaag cttgatagtc ttccctaaga ggatagacac ggaaaggatt agcaaatggt
    84481 tcaatgacta gctcatctag ctgtcttttt gtagtgatat tttccgcgtc tgatcgtttt
    84541 gttgctaatg ttgcaccaaa agacgctgct aaaactgggt cattgatctt gataattggc
    84601 ggaagcgaat catctttcat gatccaaaaa acagcatcga tcttttcgct aagatgatcg
    84661 actcggtcgg gtgtcgcata acgtgatttg actgtccgcc catttccgtt tcgtatatct
    84721 cctgttacta ggactttttc tcctttactt gtacatgtca cgcccacatt ctgacaagta
    84781 aggaaagaag aaatggccgg atcatcagac ggatagtctt gtgttttatc aaagtaagaa
    84841 ggttccaagg cagtagcaaa accatttttt cgagaaataa cgaaagcatc gtcatgcaag
    84901 atcgaaacag agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt tccagaaccg
    84961 gacaacccaa atacagccat cgtataggtc tggtcattac tagcatattg tttcatccca
    85021 ccgtggcagg caataaagcc attgcgattt cccaatgccc aagcaagcgt caaagtcgct
    85081 ttttttaatt ctccaaagta acgtaatcct agcacaaccg ctgtattatg gagagcatca
    85141 aacaaaatga gtccatttgg aaatgtttca tgtgtccatt cgggatcaca aaagatataa
    85201 agatctccct catcaaagga aacagacttt tgataagtct ctaagatctt cgaattcgct
    85261 ggctgaaaat tcagcaaata agaatacaaa ttgttctcaa atccttctgg aatcagcaaa
    85321 tgactttgca cagaaaattc ttcagatagg ccaacgatta cttttgtatg gtaaaactgg
    85381 cgcttgcgac tttgatacac agcttctctt aaaattttct cgtatttgct ttgttccttg
    85441 tctaagtcct caaagatccg ccgagcactt gctgttcttc ccacaatgct tccatcattg
    85501 aatactagtg tcctaacatc agctggtaaa tctagttctt cagcatgtga gattgttaaa
    85561 tctgtgatga tcgttcctgg actccctttt gctagttgat aagctgtctt cctatcaaaa
    85621 acttcatgaa cattattacc gtaaaatgtc gtttctacaa tcgatcgaat actggataac
    85681 agtggatttc cacttgtgat ttcgtttaat tcgagactct cttttgtact catggctcct
    85741 cctcattccc taaacaaaaa aacgttttct ttattataca ttattcgagt ttttatttgt
    85801 actgctgcgc tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg agaacttgaa
    85861 taaacaagtt tctcggtttc atcattttcc ttttatcggc ttagtaccag ccgtttgcta
    85921 accagaatgt tttagcagca tcccatgaac cataacgaga tgttacatat tgttctgcta
    85981 cacgttcttg attggcagct gaatagtcgc cgtttaagta tgaagcatct aattgataac
    86041 ggccgatgta acgtccgtta gtagctgtgt atgaaccgcc tgattctttt tgtgcgatcc
    86101 attcttttgc agagcttgaa gttggcgctg ttgcagcagc tggggcagca ggagctactt
    86161 caactgtttc aacaggtgca acgtatgtat gttcttgcgt tgctgtttca gttgtagatg
    86221 ctgtattttc tgttgttttg ttttctgttg ttgctgaaga atcatttgaa gttgggattg
    86281 ttaattgttc accaacataa atgcggttga tgtttgcgat cgaatttttt tcagcaattg
    86341 catcgatcat tgagttgtct cctgcaaatt tttgtgagat cttagataat gaatcacctg
    86401 attttactgt ataaacttca tcagcgtgag catttgtagt tcctacaaac attgcagtag
    86461 caccagcagc aaaagttgta cctaaaacaa ttttcttaaa tgaattcata ttaaactcct
    86521 ttttttctcc gttttttatt ctttcgacgc tattaacttt atcatttaga aatatttcat
    86581 aggtaaaaga aacatgacat ttaatgacaa aataacgaat tatttaatat ttgtaacatt
    86641 taaacaaata tttttttgat acaaaaccat aaaagccttg ttgtataagc aaagtaatcg
    86701 tttttctatg ttttttttat ttttgaatga aaaacgcaga ttctgtaaca ttcactgcaa
    86761 taatccataa aaaaaagcaa aaaaattttt gatttttatc aaattctctt aaaaaaatgt
    86821 aaaaaataca aaaaaaccag taattgttac aacaattact ggacaaaaac tttgaataat
    86881 gttaactatt tttttatttt aactttctcc gcaataattt ctgggcatgt tccaattcgt
    86941 ttataacgac ttcttctgtt tctttagcta atatttcatc taatacatca agccattttt
    87001 ccggttcttt tgttcctaga cgtccaatag cccaagctgc tgttcctctg atgacagggc
    87061 ggacatctgt taaacattct gaaatctcag gcaatgccgt tcgatcacct agattagcta
    87121 aagcaatcaa tgcgtttctc tgcaaaggtt tcttcccacg ccatgaacca gctaaatgcc
    87181 caaattgctg tttgaagtct ttattagaca tcgaaagcat tggctttaat tttggatata
    87241 tttcgtctac ttttggttcc atctcttcat gaaaatgaaa atcttttcct tgattgtaag
    87301 ggcagactaa ctggcagata tcacatccat aaatgacatt tcgcattttt ttacgatatt
    87361 cttccggcat catccctttt gtctgagttt gataagacaa acatcgctgg gcattcattc
    87421 ttccgtcacc aagcaatgct tttgtcggac aagcagtcac gcagcgcata cagtcaccgc
    87481 aaccaaattc tcctggttta tcaggctcaa atacaatatt agtaacgatc tcaccaagat
    87541 agacaaatga accgaactct tcagtgatca acaatccgtt tcgtccaata aatcctaaac
    87601 cagctcgctg tgctacagcg acatcgatca gttctccagt atctacttgc ggagctagac
    87661 gccattcctc ttctttttgc catttttctg ctcttgtttg gatgaattcg atcaatcggt
    87721 tcaaacggtc tctgagtata tcatggtaat cgatccccca agaagcacga gcaaactgcc
    87781 cgcgtttttc atccctaggc acttcttcat ggatcctagt aggatacgca agtgcaatgg
    87841 aaatgatcga tttcggctga tcaaatgtca tttctggata aagacgctca tcgatatttg
    87901 gatgttcaaa gccagaagta tggccagctg ctttttgttc ttccaacgat tcttttaatg
    87961 aatcaaaagg ttccgccgtg gtgaacccga ttttgtcaat tcctaatcgt ttgctttctt
    88021 gtatgatttc ttcttttaat gtcatggtct tcctcgcttg ctgttaacgg ctgtataacc
    88081 cataatatag tttttctttt ttcagctgga caaactggat ctgctgatcg gcattcttct
    88141 tttcttccat ccattttttt cttgcagcaa atacttccca ataatttgtt gaaattaatt
    88201 ttcttttgtt atctaatgca ttaaaaaaat tcaatgaaac tggttttgta cttaacagtt
    88261 catggagcct tacctcttcc catggcgaaa actcagacag atcgcgggaa tacaatactt
    88321 cttcatagag atttttttgc tgtgtgtacg tgaatgtttg cgggattttc ccaggcctag
    88381 caatttctac tagacgatta taaaacatat tcattaattt gctgttggca ataaattgac
    88441 ttttataata ggccgactgg atctttttga ttactccttc tgctttgatg actgaaaata
    88501 atgcaggcca tgctttgacg gttatttcgt cgttttgttt aactaatacg ccaggtgtga
    88561 agccgactgg agaaaggaac acaaaataac cgataccggt attttcatct aaaggctgaa
    88621 attcatcaaa caaccatttg cctatgtaca gctcttcatc tggttctgtt gtctcatttt
    88681 gatttgctat gaataattta gctaattctg cttcaagaaa ttgaaggtct tgatccttgt
    88741 cggtattttc ctgctggctg atcaatcgaa agacttcttc tttaatcgta tatttatctt
    88801 tacgtgtaaa attcatagcc acaccttcct tccttactct aactataacg gaatttcttc
    88861 aaaaaaggta tctgtacgac gaaaaacagc ataatttttt ttcatatctc ttataaaaaa
    88921 tgcaaggtct gctcctcaag ctagaccttg cacttttcag ctttcttttg tttgtgacaa
    88981 accttcatgg atcgtttcaa tattccattt catcatctga tagtaagaat ctccttgttc
    89041 tccttctttt gctatggaat cagtgaacag tttatcatag attttcaaac ccgtttcttt
    89101 tgctacccgt tccatgcttc ttgagtctac actggtttcc acgaataaaa ccggtacttc
    89161 ttttgctctt atctgatcaa tgatcgcttt catttgatca ggcgtacctt gactttctgt
    89221 attgatctcc catatataag ctgctggcaa atcatatgct cgtgaaaaat acttgaatgc
    89281 cccttcactt gttactaata attttttgtt ctcttcgata gaagcaaaac tttccttcgc
    89341 ttgtgtatct aattctttta gtttttccac atatgcttct gcattttttt tatagagtgt
    89401 cgcattttct gcatcttttt cagagaatat acgtgcgatt tcctccacat attttattcc
    89461 gttagatagg tctagccaag catggggatc tgcttttgta tgttcttcac cgctagttaa
    89521 ataaagaggt tctacatttt tgctaactgc aaaataatct tttccttctt cttttttagc
    89581 cgtttccatc aagttatcga accagctgtt acctgtttca agattcaaac cgttgtataa
    89641 aataacatct gcatcgcttg cctttttgat gtcttctggt agtacttcat attcatgcgg
    89701 atctgttccg actggtacga tactgtggat atctatttga tctgttccga cctcttttgc
    89761 catgtccgcc aagatcgaat tggtagccac gactgacaac ttttctttac ttccttcatc
    89821 cgcttggtca gaagcctgct ttccgcaacc ggctaatacc aagaaactaa ctgccaagat
    89881 taaaaagagt gatttttttg ttttcatcta tctgcttcct ttctgaaata aaattccttt
    89941 tgttggagaa aataaaaaag caaggataaa aaatgcggta catgctaaca cgatcgtagc
    90001 tcctgatggc caattgtaac tataactgaa aaacacaccg acaactgcac ttagcatacc
    90061 gattcctgca gctgtaatga tcattttcag taaatggttc gttagcaagt aagccgtggc
    90121 ggctggtgtg atcaacatgg caatcaccaa gattgttcct actgtctgta aactgactac
    90181 agccactaat gtcaaaaaga acatcaaaag ataatggatc agcgatgtgt tcagcccata
    90241 agcttttgcc attgtcggat cgaatgatgt gatcttcaat tctttataaa agaaaaagac
    90301 aaatatcaag acgattccac taacgagtgc tgtcagcaac aaatcgcttt ccctaacagc
    90361 taagacattc ccaaataaaa tatgatacaa atctgtcgca ctctgggcat atgaaatcaa
    90421 gataatccct aatgcaaaaa aggagctaaa gacaattcca atcgctgtat catttttcaa
    90481 tcggctccgc tgagtcacga aaccaatcac tgctgctgtt agcatcccaa aagcagtggc
    90541 tccaaagatg taactaaaac caaacatata agaaatggct acacctggaa gaactgcgtg
    90601 agagatagcg tctcccatca aagacatccc tcgtaaaata ataaaagaac cgatgactcc
    90661 agaagcaagt cctacaagca tggaagtgac caaagcgtat tgcaggaatt gataattcat
    90721 taatccatca ataaaggatt ggatcatttt ttctctcctc cttttactaa atgtctgatg
    90781 atctcaccat aggccaattg aaggttcttc gatgtaaaga cttcttgtac tggaccggaa
    90841 gcgatcagct gtttatttaa aagaataacc tcatcgaaat attcttctac tttatgaaga
    90901 tcatgatgga cgatcaaaat cgtttttcct gaattcttca attcctgcaa gatgtcaaag
    90961 atctttcgtt cacttaacgc atcaatccct acgaatggtt catctaaaaa gatccattct
    91021 gctccttggg ctagagctct tgcaataaaa actctctgaa gctgtccacc cgatagttcg
    91081 ctgatctgtc ttttggcata ttcttccatc cctacttttt tcaaagcttg tcttgcacgt
    91141 tctttttctt ttttcccagg tctttgtcca attcgtaaag atggatatgt tcctaaaagt
    91201 acaacgccta atacatcaat tggaaaggaa agatccaatt cacttcgctg ttccacgtag
    91261 gctatttttt tacggactga gtttaccgac tgtccagaaa aggtgacttt accagtagta
    91321 gctggtatca actctagcaa agatttcata aatgttgatt ttcctgcacc gtttggtccg
    91381 ataataccgg taattttttg tggatttatc gtcaagttga tagttttcaa aacagttttc
    91441 ccttgataag cggctgaaag gtcttgaatt acaatggccg tacgttccaa atcttacact
    91501 cctttttagg tttacctaac tttttattta aatatagttt aactaaaatg gaaagcattt
    91561 tcaagtagaa tgatgaaaaa gtttttttcg aattttcctc gcattttatg aaaattttct
    91621 gtagaatcac atcaagagtt caataaggct aacctaataa tgaaaaacat gtgttgaaac
    91681 gtttgattat tttttcttgt tgactcaaca acgaaaggag tttttgtatg gaagaagaaa
    91741 agttaactcg aagtcttagt gcccgtcata tccaaatgat cgcactaggt ggaacgatcg
    91801 gtgtcggtct gtttatgggt gcctcctcaa ccatacgttg gacagggccc tcagtgatgg
    91861 gagcctatgc gattgcagga ttctttttgt atttgattat gcgtgcttta ggcgaaatgc
    91921 tttacgttga tccttcgact ggttcttttg caaattacgc gagcgagtac atccatcctg
    91981 tggctggcta cttgaccgct tggagtaata tttttcaata tattgtcgta ggaataagtg
    92041 aagtgattgc tgtaggatct tatatgaatt attggtggcc tgatttgccg gcaattattc
    92101 ccggaatcat tgtcgtcttg tttcttatgc tggcaaatct tatttctgtc aaggcgtttg
    92161 gcgaattaga attttggttt tcgatcatca aagtcataac gatcattttg atgatcattg
    92221 caggtcttgg ggtaatctta tttggatttg gtaatcatgg tcaggcagta gggatttcaa
    92281 atctttggaa aaatggtgga ttcttcactg gaggcgtcaa aggatttttc tttgcattat
    92341 cgatcgttgt tgcttcctat caaggaatcg aactgatcgg aatgactgct ggtgaagcag
    92401 agaatcctaa aaagacgatc attgaagctg tccagtccac tatcggtcga atcttgattt
    92461 tttatattgg tgctattttt atcattgtga gtatctatcc gtggaatcaa ttgagtgaga
    92521 ttggttcacc ttttgtacaa actttttcta aagtcggcat tacatttgct gcaggactga
    92581 ttaattttgt cgtgattaca gcggcattat caggttgcaa ttcagggatt ttcagcgcaa
    92641 gtcgtatggt ctatacactt gccataaatg gaaagatgtc taaaaaattt ctgaaactat
    92701 ctcgtcacgg tgcgcctttt tatcctgtcg tagcaatctc aggtggaatc ttaattggtc
    92761 tgatcttaaa ttatcttcta ccaatgttca tcaaccagtc agaaaatatt ttcgttttcg
    92821 tatacagctc aagtattttg cctggtatgg ttccttgggt agtgattttg atcagcgaga
    92881 ttcgcttcaa aaagaagcac gcagataaaa tgcatgatca tccttttaaa atgccactat
    92941 ctccttatac gaattatgtg acacttgctt ttttagctat cgtattgatt ttcatgttta
    93001 tcaatcctga aacgagaatc tcattgatta ttggactcgt tttcttgctt tacatgacga
    93061 tccattactt tgtacgcgaa aaaagaaccg gaaaataaaa aaagaacgaa gcttcacctt
    93121 agtggaagct tcgttctttt ttattgcttt tatcaattca attttagcgt ctcaccggga
    93181 gtcaggaaat aattctccat gctcatccca ttcagcgaca agatcgtttc tactggtacg
    93241 ccagttcgtt cggctatttg atttggacct tctccttcca aaactacggt tgtcgcagcc
    93301 tgtgaagtcg cgctgttggt attagtttca gaggaatctg ttgtgtcttg tgttgttcga
    93361 gcttgcattt cagaagcttc taccgactct gctgtctcag aatcagaaga tgttgtgtct
    93421 tgtgtgcttg ttgactctgc ttgaagagag gcgctagtct gcaaataaat atcggaaatc
    93481 ttagcgacat gattcgtata attagccgat aattgattga tcaaagtatc taagtctaca
    93541 ccgtctttat tttctgctgc ctgatacgct gcacgtaatt ttctgatccc ttcgtcggag
    93601 attgcttgaa gctcacgtgc tttttggtta gcaactgctg ataaaccagc tattccctct
    93661 tgatttccct gaatttctgt ctggtattct tcaatcaatg caggcgtctt ttcttcgatc
    93721 tttttcgaat aatcatttac gattgcttga agttgctctg gcaaaccatt tgctgttttt
    93781 tcttcagaag tttgtgtctc ttttgtttta gttgatgact cacttgtttg tttcgtctct
    93841 gttttctttg tcgttgtttc cgttatggtc gtacttttcg cttctgacga attttttcca
    93901 tgaaaatata gacccgcaac tcctcctgct atgatcaaaa acacggcaac tgctgcccca
    93961 atcatgatca tccgcttacg agctgcctgt ttttgctgtc ttcttcgggt catccgaaca
    94021 ttttctcccc actcattttc atcatacatt tttttcacca ccaattttta tgtataatag
    94081 cgttatcaaa cgcttcatat tcttattgta gcaaataatt gtcgctgtgc acatttttat
    94141 ctttgttatt tataagaaaa tttcaccagt tgagatgatt ccaagattgt ccgtcgattt
    94201 ctccttgcag ctgcattgtt cgttcgtcta tctcagccat cagtttcttt atttcatata
    94261 agagcgcacg gtcttgatat tctgattttt cgcttaattc atctaattgt tggatcagcc
    94321 aatcatttgt cataatgaag ttcctttcat ttcttgcagt gtaaaggtca agtcttcgat
    94381 ctgctctttt gcctcagtca gtgcttctac gatatatgct tgtttttcag attcttcttc
    94441 ctgcattttc tgattttcct gtactctttg aataaaccag tcaatccgct gagtcagcga
    94501 tggtttgcct tccaatgaga gatactgctg ataagcaatt agcttctccc aacgtttttc
    94561 ctgggataaa tacataaatt gtgctaaaac gaatggcgga agataggtca tatggaattt
    94621 atttgcgatt cgctgatacg gcctcaaaaa ttcggaaatc gtatattctt cttttcctcc
    94681 agcttggtat tctttttccg ccacacctgt tgtcaatacg attcctagtt ctttcccttt
    94741 taatacatgt gctgctcgtt ccaagacatt atcttgccaa atttttaaat gagcaggaga
    94801 actataccag taaaacggaa actggaaaat gatccgatca tgctgggcca agagctgtag
    94861 ttcagtctct atatctattt ttccgtctgg ataacttgat tccaaatgat gccaagtagc
    94921 tggtaaacca gcagaagctt ctttgaaaaa ttgctgattt aaagattctt cgatcgttgg
    94981 atggctaatg atgataagtg tacgcatccc ttttcctcct ttttagtctt cgctttacag
    95041 tgtagcataa ccgccacaag tttcttttgc cgatgcttgt cattttaacc agactaatca
    95101 ggttgtccaa gaaactgtgg tttgtttttc caactgtttt ttcaaggtat ccaaagcaat
    95161 attcttaaaa tttttgtttt tcatacgttt acgatagttc gtagccgttt ctccggtact
    95221 ctttttgaac attcggctaa atacgactag actattgaac cctacttgat aggcaatact
    95281 ttccacggat tcatccgtca gagaaagaag aaacgcccct cgattgatcc gtaccccgat
    95341 caaatattcc ttgatactgg tacccatatg atttttgaat actcgcgaca aatggctccg
    95401 attgaccgct aaatgctggg cgatttcctc aacagacaat ttttcagcat aatgtgcctc
    95461 gatgtatttg actgtttcaa cagctaaaga ggaatgaacc ttttgtacac caccgctgac
    95521 ctttccgcca tcttttaaaa ggactgataa aaaacggtag gttaatgctg ttaactgtaa
    95581 ttcattttcc aaggtttctt ccgtatcttt catgcattct aaaataatgt cgatatattt
    95641 ttgtatgtca gaagagacca tcgtgtattg gtcttctctg aaaagcgact gccgaatgat
    95701 ttcttctgca gcactcccac caaatgaaag ccagcaatac atccacggat cttctccatc
    95761 tgataagtaa aacgtcgagt ctcctggacg aatcaagaac agatcacctt ttttcaattg
    95821 gaattgttga tttttcacat gataagatcc tttgccttcc atcacgacat gcaggatgta
    95881 atcattgcga atagcaggac caaaagaatg aaacggcatc gttttagaga aaccacaaaa
    95941 atcaaaatac aattcttttt ctacttgttg atgttccttt tttaaaaaaa tcgattgctc
    96001 cacgtctatc cctccttact cctttagtat aatgcaacaa aaagttaaat aaaagtcaca
    96061 gaaatatatt aaaaaggaag cgatttcttg ttaagtttaa gtcattaaaa gatctttgtt
    96121 attcgttgta accggtttac ttagtattat atattgaaca ggagaggaat acagattatg
    96181 aaaagcaaaa tgatccaacg tgtgtcctac gctttaggcg cttttggaca cgacacattc
    96241 tatgttacat taagcactta ttttatggta ttcgtgacaa gccagatgtt cgcaggaaca
    96301 gataaggcaa cgaatgcaaa aatgattgct acagttacaa gcttagttgt aggtatccgc
    96361 ttagttgaaa ttatttttga tcctttgatt ggtggcatca tcgataatac tcgtacaaaa
    96421 tacggtaaat tcaaaccatg gttagttatc ggcggcgttg ttagttccgt actcttggta
    96481 gcaatcttta ccaatttctt tggcttagct actcataata cgactttatt tatcatatta
    96541 tttgcaatcg ttttcatctt attggatagt ttttattcat ttaaggatat cgctttttgg
    96601 tcaatgattc cagctttgag tacggaaaca aaggaacgtg aaaaatttgc tacgtttgct
    96661 cgtttcggct cttctctagg tgcaaatggt actactctag tcgttgtccc tatcgttact
    96721 ttctttacct atcttgttac tcataaacat attgaaggcg cttcaggctg gttctggttc
    96781 ggtgtgattg ctgctgttat ttcaggcggt actgcgatta tcactgcctt gggcacaaaa
    96841 gaagtcgata ctgcgatccg tcagcaaaat gaaaaagctg ggatcaaaga tgtgttcaaa
    96901 gcagttgctc aaaatgatca gttgatgtgg cttgcccttg cttatatcgc ttatgcgatt
    96961 gccaatgcag caacaactgc cgtattattc tacttcttca aatatgtact tggccaacca
    97021 actgaatttt ggatcgttgg tctagttgct gccttacttg gtttagtagc tgttccacta
    97081 ttcccaatgc ttacacgcgt catctctcgt cgctacgttt accttggagg gatcgcaatg
    97141 atgatttctt cttacttttt ctttacgatc gcaggttcaa gtttgccaat cgttatcatc
    97201 gggctagtat tgttctactt ccctcaacaa ttgattttct tatccgcttt gatgacgatc
    97261 acagactctg ttgaatatgg tcaatggaaa aatggtatcc gtaacgaagc tgttactcta
    97321 tcaattcgcc ctttactaga taaaatcgct ggtgctttgt ctaacgggat cgtagggttt
    97381 gtcgctatcg cttctgggat gactggtaat gctactgctg ctgatatcac tgctcatggc
    97441 gtaacgactt tcaaagctta tgcattctat gctcctgctg ctttgatgat tttctccgct
    97501 attatttttg cttggaagat tacattgaca gagaaaaaac atgcacaaat cgttgagaaa
    97561 ttggaaaaca aattggctcc agctgataca atggaagatg aacttcacga tgcagtagat
    97621 ccttcccatt aagaaaggat cttgaaaatg aagattacag aaaaagattt tggccaaggt
    97681 tatcacttga taaccttgga gaacaaaaac aagctagcac tttctatctc tgatttaggt
    97741 gctagaatcg tcagtttaaa atcaaatgat cgagaattag ttttgggatt tgacaccgct
    97801 gaagaatata tcgaaaaaga tccgtatatc ggtgcttcta tcggtcgcac cgcagggaga
    97861 atcgaaaatg gccacttttc tctcaatgga aaaacttacc aattagccac agatccaaaa
    97921 actggacata atctgcatgg tggtgctcct ggatttgaat taaaaaaatg gtcttatgtc
    97981 attttgaatg gcgaaaatga agcttctgtc atttttacta ctacaagtcc cgacggagaa
    98041 catggttttc caggtacaat ggatgtggaa atccgctata ctttgacaaa agataatatc
    98101 tggcgagtga cctctcgcgg caccagtgac caagatactt tattcaatcc gacaaatcat
    98161 gtttacttca acttgacggg agatgcttct cagtcaatcg atcaacatga gctttggctc
    98221 aatagcgaag cttatgctcc tttgcgaaca gatagtattc ctataggggt aaaagaaaat
    98281 gctgcaggaa gtgctttcga ttttcaaata cctaaaaaat tagcgtccgt ttttgctagt
    98341 gatttggatc aaaaaaatct tgttgacgga atcgatcatc catttttctt aaaagaaacc
    98401 ggcttgggta aagaagccgc tcgcttgact agccccgata aaagaatcca agtagatatt
    98461 gctacagatg cttctagtgt ggttattttc actgcaaatt tcggcacaga aacaccagaa
    98521 atgcgcaacc gaaaactggc acatcacggt ggcatcacat ttgagactca aacagctcca
    98581 ggtgcagagc gcttctcagc atttggttcg attcatttaa aagccggatc agtatttgaa
    98641 acagtgacag aattcaaaat caaaacaaga aaggaataac tcatcatgga aatcaaaaga
    98701 agcttaaaca caaaatttgc cgaaacattc ggacctaaaa aaactacaca atacttctca
    98761 ccaggacgca tcaatttgat tggtgaacac acagattaca atggaggcca tgtcttcccc
    98821 gcttccatca cttatggaac gcaaggtgta gcagcacctc gagacgataa taaaatatta
    98881 gtttattcca caaactttga cgatatcggt gtcattagtt ttactttaga tgagctagaa
    98941 tatgataaaa aagcaaactg ggcaaattac gtaaaaggaa tggtccttaa attaaaagaa
    99001 gctggacact caatcgatca tgggtttgag ttattagtgg aaggaacaat ccctaatggt
    99061 gcaggacttt ccagtagcgc ttcattagaa ttattagtag gtgttgtatt agaagatctg
    99121 tttgatttaa aaacagatcg cttggaacta gtccaaacag gtaaaaaagt agaaaatgaa
    99181 ttcatcggtg tcaattcagg tatcatggat cagtttgcca tcggcttcgg tgagctagat
    99241 catgcaatct tattagatac aaatacgctg aaatacgaaa tggttccagt gaaactagat
    99301 ggttatgcaa tcgtcatcat gaatacgaat aagcggcggg aattggcaga ttcaaaatac
    99361 aatgaacgcc gtagcgaatg cgaagaagcc ttggcacgtt tgcaaaaaac tttgcctatc
    99421 tcttctttag gagacttaga tgaagaagaa tttgaatcaa ctattgacca aatcggcgat
    99481 gatacattga tacgcagagc tcgccatgcc gtttctgaaa atcagcggac tttgaaggca
    99541 aaagctgaat tagaagctgg gaacttagaa gcatttggtc aactgttaaa tgattctcac
    99601 cactctcttc gctatgatta tgaagtaact gggatcgaat tagatacact agtagatgct
    99661 gctcaaaaac aagaaggtgt cttaggtgca cgaatgacag gagctggatt tggtggctgt
    99721 gcgattgctc ttgtcaaaga agaaaatata cctgccttca aaaacaatgt ctatgatgaa
    99781 tacatgaaag ttgtcggcta tgctccggaa ttttatgttg cacacattgg aaatgggaca
    99841 acaaagatcg atccagaagc tgttcatgtt tgataaaaaa atcaacgatc tcagctaaaa
    99901 acaaatagat aaaaataacc tctcagcaat ttccaaatgt gagccttttg ctcgtatttg
    99961 aaaattgctg ttttttattg acacggaaag agaacgtgtg ttctaattgt gttgaagagg
   100021 tgattgttat gtgggcgaat caaaatccgg tatttgttta tgaaaaagaa ccttcaagag
   100081 atattttatg tattgactgc aaatcttttt acgcctccgt agagtgcgtt gaaaaggatc
   100141 ttgatcccct tacaactaaa ttagtagtca tgtcctatcc gtccgattcg acagaaacac
   100201 ggggtagcgg attaatcttg gcttccagtc ctgcagcaaa aaaagcttac ggcatcacca
   100261 atatcagccg tgccagagat cttcccttcc cctatccaag tgatttatat attgttgccc
   100321 caaggatggc ctattatatg gaaaagaaca gagaaatcaa ttctatctat aaaaaatatg
   100381 cagacgaagc gaaccatcat gtctattccg tcgatgaaag cttccttgat gtaacaaata
   100441 gcatggcact ctttggtaaa acaaatgcgt acgacatggc taaactgatc cataaagatg
   100501 tgtttgagca gaccggaatc tacacgacta taggaattgg cgataacccg ctacttgcta
   100561 aactagcctt agacaatggc tcaaaagacg gaaagcaaat gtttgctgaa tggcgttatg
   100621 aagatgtacc agaaaagtta tggaaaatct cagatatcac tgacttttgg ggaatcggca
   100681 aacgaacagc aaaacgtctg aaacaaatgg gtatacattc tgtttatgat ttagctcacg
   100741 cggattatta tcacttgaaa agcaagctag gggtcatcgg tactcagctt tatgcccatg
   100801 cttggggcat cgatcgaagt tttttgggac aagaatatac accaaaatca aaaagtatcg
   100861 gaaatagtca aatcctagat agagattata caagacgaga agaaatcgag atcgttatca
   100921 aagaaatggc cgaccaagtc ggcactcgct tgagacgatc tgcagcaaaa acacaagtag
   100981 tcagcttatg ggtaggatac tctttaggct atcttgatcc aaatggcaag accgggtttc
   101041 accagcaaat gaaaatcgaa gcgacaaatg ctagcagaga tctagcagat gctttattga
   101101 ccattttcca ccagcattac cactaccagg atattcggcg tgtaggcgtg aactgttccg
   101161 acctcgtata cgcgacaggt ttacagctta acctttttga agatcctgaa aagcagataa
   101221 atgaagcgaa agttgatttt gttgtcgata cgattagaaa aaaatacggc tttcaatcaa
   101281 tcatccatgc gcatagtctc ttgcaaggag gacgcgccat cgcacgtagt tctctcgttg
   101341 gcgggcatgc aggtggtatg agtggattag aaggtggaaa agatgagacg gacagcaaaa
   101401 aaattcattg actataacga gtatcgagat cggccatttg gattaaaatg ggggactgct
   101461 tttgcgatgg aagaactagt caacggtatc aaaaaaaatg aagaagaagc acgcaaacag
   101521 cctcttccta aacaacaaat gacattgcaa gaaatcgata gtatactgac agaagccttt
   101581 ttatctcgta aagcagtaat cattcagctc aatttaaaag atgaatttgg aagactcttg
   101641 gatgaggtcg aagggcactt cattggtgaa gcctatgaag attactttat gattgaccat
   101701 cagccgatat tgtgggaaga cgtacggtat attgagttaa aggaaacaaa aaaatggttt
   101761 gtgacatgag aggttgtgac agaagtgatc aacttcaaaa aataagaaag gatttttcga
   101821 aaattgcttc ttaaattttt gtggaatttt ggcttatttt tcgaagaagc aacttctgga
   101881 acaacgtata ttagatatca gaggttgtga aaaagtcgct tagttttgag taacaagcca
   101941 aggcgctgat ttcacaacct ctgtctatct atccatctat tcggtaagat tcatgcatga
   102001 cgtcttcttt atttagtatg tagagccctt tttcttctga ccattcaaca taaatcagct
   102061 gttttacatc tgcatagcct tctttcttca agttctccat aagccatgct tcagtcaatt
   102121 gattggactg aagcacttta tgctgaattt gcccttcatc tacaagcagg atcgataaag
   102181 ctttgtcttc atctgatttt ttcaatacac tcatttgacc ggcattctct aggataacat
   102241 gtttggcatt ttcaagaaaa aagcattctt gctgtcttaa gattgctcgc aactgctcca
   102301 tctcgatatg gttatttgtc aactctgtca tgttgatgac gccgtctttg attagaacag
   102361 atggctcgcc tttgacccaa cgattgacct tttcattttt ttggacgata cgttcgatac
   102421 cataaatcat tactgcccaa agcgcaatgg caaataggac atgccctaca tggacattgt
   102481 catcataggt tgattcttct aagatcccac ctaaaacaag cgtatagact aaatcaaacg
   102541 gtgtgatttc tgacatggat ttcttcccaa gcaaacgtac cactaataat aaaccgatca
   102601 acccgaacac cagtttcatt gtaattgaaa aaatcatttt ttctccccct aactatctgt
   102661 taattaaatt atatatgctt tctcacgaac acgcatggaa tatacaagga agaaatgtat
   102721 ccttttacta aaaaaaggac tgtgacactg tagtgacccc caaaagttag acttttttgg
   102781 agtggagaaa tccactcctt ttttttatgc tctaaaatga tatttttaca caaccgttac
   102841 ggttgtttta cgaaattgga cg
//
LOCUS       DARPZJ010000003        93454 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.003, whole genome shotgun sequence.
ACCESSION   DARPZJ010000003 DARPZJ010000000
VERSION     DARPZJ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 93454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.003"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            83..970
                     /locus_tag="SLE23_000260"
     CDS             83..970
                     /locus_tag="SLE23_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEI8467197.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="SLE23_000261"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="SLE23_000261"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEI8467198.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="SLE23_000262"
     CDS             2272..2718
                     /locus_tag="SLE23_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEI8467199.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="SLE23_000263"
     CDS             2991..4343
                     /locus_tag="SLE23_000263"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HEI8467200.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="SLE23_000264"
     CDS             4514..4801
                     /locus_tag="SLE23_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467201.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5027..5470
                     /locus_tag="SLE23_000265"
     CDS             5027..5470
                     /locus_tag="SLE23_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8467202.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5476..6660)
                     /locus_tag="SLE23_000266"
     CDS             complement(5476..6660)
                     /locus_tag="SLE23_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8467203.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGCAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6928..7626
                     /locus_tag="SLE23_000267"
     CDS             6928..7626
                     /locus_tag="SLE23_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEI8467204.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7633..8310
                     /gene="nth"
                     /locus_tag="SLE23_000268"
     CDS             7633..8310
                     /gene="nth"
                     /locus_tag="SLE23_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEI8467205.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8436..8969)
                     /locus_tag="SLE23_000269"
     CDS             complement(8436..8969)
                     /locus_tag="SLE23_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467206.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9266..11647)
                     /locus_tag="SLE23_000270"
     CDS             complement(9266..11647)
                     /locus_tag="SLE23_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEI8467207.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11637..12284)
                     /gene="recU"
                     /locus_tag="SLE23_000271"
     CDS             complement(11637..12284)
                     /gene="recU"
                     /locus_tag="SLE23_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEI8467208.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12348..12887
                     /locus_tag="SLE23_000272"
     CDS             12348..12887
                     /locus_tag="SLE23_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEI8467209.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12977..13396
                     /gene="gpsB"
                     /locus_tag="SLE23_000273"
     CDS             12977..13396
                     /gene="gpsB"
                     /locus_tag="SLE23_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEI8467210.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13418..13785
                     /gene="rnpB"
                     /locus_tag="SLE23_000274"
     ncRNA           13418..13785
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="SLE23_000274"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13994..15160
                     /locus_tag="SLE23_000275"
     CDS             13994..15160
                     /locus_tag="SLE23_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEI8467211.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15206..16702
                     /locus_tag="SLE23_000276"
     CDS             15206..16702
                     /locus_tag="SLE23_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HEI8467212.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16783..17466
                     /locus_tag="SLE23_000277"
     CDS             16783..17466
                     /locus_tag="SLE23_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8467213.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18111..19301
                     /locus_tag="SLE23_000278"
     CDS             18111..19301
                     /locus_tag="SLE23_000278"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HEI8467214.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19403..20356
                     /locus_tag="SLE23_000279"
     CDS             19403..20356
                     /locus_tag="SLE23_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HEI8467215.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20425..21774
                     /locus_tag="SLE23_000280"
     CDS             20425..21774
                     /locus_tag="SLE23_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467216.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21957..22280)
                     /locus_tag="SLE23_000281"
     CDS             complement(21957..22280)
                     /locus_tag="SLE23_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467217.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22409..23572
                     /locus_tag="SLE23_000282"
     CDS             22409..23572
                     /locus_tag="SLE23_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEI8467218.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23642..24991
                     /locus_tag="SLE23_000283"
     CDS             23642..24991
                     /locus_tag="SLE23_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEI8467219.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25036..25467)
                     /locus_tag="SLE23_000284"
     CDS             complement(25036..25467)
                     /locus_tag="SLE23_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467220.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25855..28497
                     /gene="alaS"
                     /locus_tag="SLE23_000285"
     CDS             25855..28497
                     /gene="alaS"
                     /locus_tag="SLE23_000285"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEI8467221.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28697..29293
                     /locus_tag="SLE23_000286"
     CDS             28697..29293
                     /locus_tag="SLE23_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8467222.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29415..30563
                     /locus_tag="SLE23_000287"
     CDS             29415..30563
                     /locus_tag="SLE23_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEI8467223.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30601..31014)
                     /locus_tag="SLE23_000288"
     CDS             complement(30601..31014)
                     /locus_tag="SLE23_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HEI8467224.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31093..31524
                     /locus_tag="SLE23_000289"
     CDS             31093..31524
                     /locus_tag="SLE23_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEI8467225.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31623..31856)
                     /locus_tag="SLE23_000290"
     CDS             complement(31623..31856)
                     /locus_tag="SLE23_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HEI8467226.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32039..33709
                     /locus_tag="SLE23_000291"
     CDS             32039..33709
                     /locus_tag="SLE23_000291"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEI8467227.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33856..34242
                     /locus_tag="SLE23_000292"
     CDS             33856..34242
                     /locus_tag="SLE23_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467228.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34229..34927
                     /locus_tag="SLE23_000293"
     CDS             34229..34927
                     /locus_tag="SLE23_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8467229.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34932..35396
                     /locus_tag="SLE23_000294"
     CDS             34932..35396
                     /locus_tag="SLE23_000294"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEI8467230.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35393..36304
                     /locus_tag="SLE23_000295"
     CDS             35393..36304
                     /locus_tag="SLE23_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEI8467231.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36539..37078
                     /gene="pyrR"
                     /locus_tag="SLE23_000296"
     CDS             36539..37078
                     /gene="pyrR"
                     /locus_tag="SLE23_000296"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEI8467232.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37092..38375
                     /locus_tag="SLE23_000297"
     CDS             37092..38375
                     /locus_tag="SLE23_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEI8467233.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38388..39314
                     /locus_tag="SLE23_000298"
     CDS             38388..39314
                     /locus_tag="SLE23_000298"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEI8467234.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39333..40613
                     /locus_tag="SLE23_000299"
     CDS             39333..40613
                     /locus_tag="SLE23_000299"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEI8467235.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40618..41694
                     /gene="carA"
                     /locus_tag="SLE23_000300"
     CDS             40618..41694
                     /gene="carA"
                     /locus_tag="SLE23_000300"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEI8467236.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41699..44884
                     /gene="carB"
                     /locus_tag="SLE23_000301"
     CDS             41699..44884
                     /gene="carB"
                     /locus_tag="SLE23_000301"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEI8467237.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44938..45714
                     /locus_tag="SLE23_000302"
     CDS             44938..45714
                     /locus_tag="SLE23_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEI8467238.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45711..46643
                     /locus_tag="SLE23_000303"
     CDS             45711..46643
                     /locus_tag="SLE23_000303"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEI8467239.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46640..47356
                     /gene="pyrF"
                     /locus_tag="SLE23_000304"
     CDS             46640..47356
                     /gene="pyrF"
                     /locus_tag="SLE23_000304"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEI8467240.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47363..47992
                     /locus_tag="SLE23_000305"
     CDS             47363..47992
                     /locus_tag="SLE23_000305"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEI8467241.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47980..48294
                     /locus_tag="SLE23_000306"
     CDS             47980..48294
                     /locus_tag="SLE23_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467242.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48332..48973
                     /locus_tag="SLE23_000307"
     CDS             48332..48973
                     /locus_tag="SLE23_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8467243.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49016..49708
                     /locus_tag="SLE23_000308"
     CDS             49016..49708
                     /locus_tag="SLE23_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HEI8467244.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49705..50607
                     /locus_tag="SLE23_000309"
     CDS             49705..50607
                     /locus_tag="SLE23_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8467245.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="SLE23_000310"
     CDS             complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="SLE23_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HEI8467246.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52661..53284
                     /locus_tag="SLE23_000311"
     CDS             52661..53284
                     /locus_tag="SLE23_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467247.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53734..54783
                     /locus_tag="SLE23_000312"
     CDS             53734..54783
                     /locus_tag="SLE23_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8467248.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54780..55661
                     /locus_tag="SLE23_000313"
     CDS             54780..55661
                     /locus_tag="SLE23_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467249.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55664..56434
                     /locus_tag="SLE23_000314"
     CDS             55664..56434
                     /locus_tag="SLE23_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8467250.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56713..57567
                     /gene="aroE"
                     /locus_tag="SLE23_000315"
     CDS             56713..57567
                     /gene="aroE"
                     /locus_tag="SLE23_000315"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEI8467251.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57745..58908
                     /locus_tag="SLE23_000316"
     CDS             57745..58908
                     /locus_tag="SLE23_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8467252.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59025..59435
                     /locus_tag="SLE23_000317"
     CDS             59025..59435
                     /locus_tag="SLE23_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8467253.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59609..61837
                     /gene="topB"
                     /locus_tag="SLE23_000318"
     CDS             59609..61837
                     /gene="topB"
                     /locus_tag="SLE23_000318"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEI8467254.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGNLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62008..62292
                     /locus_tag="SLE23_000319"
     CDS             62008..62292
                     /locus_tag="SLE23_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467255.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62452..62688
                     /locus_tag="SLE23_000320"
     CDS             62452..62688
                     /locus_tag="SLE23_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8467256.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62685..63083
                     /locus_tag="SLE23_000321"
     CDS             62685..63083
                     /locus_tag="SLE23_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEI8467257.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(63750..64694)
                     /locus_tag="SLE23_000322"
     CDS             complement(63750..64694)
                     /locus_tag="SLE23_000322"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEI8467258.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64990..65934)
                     /locus_tag="SLE23_000323"
     CDS             complement(64990..65934)
                     /locus_tag="SLE23_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467259.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66155..67369
                     /locus_tag="SLE23_000324"
     CDS             66155..67369
                     /locus_tag="SLE23_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8467260.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67391..69406
                     /locus_tag="SLE23_000325"
     CDS             67391..69406
                     /locus_tag="SLE23_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HEI8467261.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69489..70862)
                     /locus_tag="SLE23_000326"
     CDS             complement(69489..70862)
                     /locus_tag="SLE23_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEI8467262.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70888..71172)
                     /locus_tag="SLE23_000327"
     CDS             complement(70888..71172)
                     /locus_tag="SLE23_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8467263.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71174..73189)
                     /locus_tag="SLE23_000328"
     CDS             complement(71174..73189)
                     /locus_tag="SLE23_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8467264.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73368..73673)
                     /locus_tag="SLE23_000329"
     CDS             complement(73368..73673)
                     /locus_tag="SLE23_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HEI8467265.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73762..74793)
                     /locus_tag="SLE23_000330"
     CDS             complement(73762..74793)
                     /locus_tag="SLE23_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8467266.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75000..75875
                     /locus_tag="SLE23_000331"
     CDS             75000..75875
                     /locus_tag="SLE23_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8467267.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76027..76869)
                     /locus_tag="SLE23_000332"
     CDS             complement(76027..76869)
                     /locus_tag="SLE23_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8467268.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76961..78838)
                     /locus_tag="SLE23_000333"
     CDS             complement(76961..78838)
                     /locus_tag="SLE23_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8467269.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78835..80256)
                     /locus_tag="SLE23_000334"
     CDS             complement(78835..80256)
                     /locus_tag="SLE23_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8467270.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80259..83648)
                     /locus_tag="SLE23_000335"
     CDS             complement(80259..83648)
                     /locus_tag="SLE23_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEI8467271.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            83905..85297
                     /locus_tag="SLE23_000336"
                     /pseudo
     CDS             83905..85297
                     /locus_tag="SLE23_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(85370..86017)
                     /locus_tag="SLE23_000337"
     CDS             complement(85370..86017)
                     /locus_tag="SLE23_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEI8467272.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(86025..86711)
                     /locus_tag="SLE23_000338"
     CDS             complement(86025..86711)
                     /locus_tag="SLE23_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467273.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(86717..87790)
                     /locus_tag="SLE23_000339"
     CDS             complement(86717..87790)
                     /locus_tag="SLE23_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467274.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            88012..88686
                     /locus_tag="SLE23_000340"
     CDS             88012..88686
                     /locus_tag="SLE23_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8467275.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            88691..90031
                     /locus_tag="SLE23_000341"
     CDS             88691..90031
                     /locus_tag="SLE23_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8467276.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(90180..91166)
                     /locus_tag="SLE23_000342"
     CDS             complement(90180..91166)
                     /locus_tag="SLE23_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HEI8467277.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            91890..92921
                     /locus_tag="SLE23_000343"
     CDS             91890..92921
                     /locus_tag="SLE23_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8467278.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            93030..>93454
                     /locus_tag="SLE23_000344"
     CDS             93030..>93454
                     /locus_tag="SLE23_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEI8467279.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        29896 a        16576 c        18962 g        28020 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa
     4981 taggaaacaa aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca
     5041 actgctaata gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga
     5101 aatggaaaaa gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg
     5161 gaaaatccct gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc
     5221 catcagtaag ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga
     5281 agagaataaa aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag
     5341 acacgagcaa ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc
     5401 aaaagaagaa tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag
     5461 tagcaaatga agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa
     5521 tccgaatacc gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc
     5581 gatgacgcgc gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt
     5641 atctgagaca gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa
     5701 accataacag ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt
     5761 gatgaataga taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga
     5821 aaattttttg agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat
     5881 caaagagaag cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg
     5941 agaaaagata gattgaagag agccagctgc caaccaaaca gcacaacctg ctgtcaataa
     6001 aggaataacg gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga
     6061 gaaacttaaa tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc
     6121 ataaacggca tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa
     6181 ctcagctaat agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc
     6241 catccatcca aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata
     6301 taaggtggag atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca
     6361 tatcgaattt cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat
     6421 aaggatcgga tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa
     6481 ggcagctaga gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga
     6541 gtgagaataa ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc
     6601 agtgaataag acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat
     6661 gtaaaaactc ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt
     6721 gtttccttgt caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag
     6781 tgaagatacg catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg
     6841 accgatcagt gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt
     6901 atactgtgat tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga
     6961 caaacagtca tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa
     7021 gaatttttat ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat
     7081 ttgcagatga ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat
     7141 cgtctcgtaa caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca
     7201 gatcgatata atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa
     7261 aaaaaatacg aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa
     7321 caagaatttg gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa
     7381 gaagaccatt atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag
     7441 gcttatagtt ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt
     7501 acaaaacaac aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa
     7561 gtagaacagt cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag
     7621 gagtagcgga atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga
     7681 atgtttcccg aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca
     7741 gtgatcttaa gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt
     7801 gcctcttttc cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa
     7861 ataaaaacga ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag
     7921 ctgattgaac gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct
     7981 ggtgtaggca gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc
     8041 gcagtagata cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct
     8101 acggtcatgg aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag
     8161 acacatcata cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc
     8221 gaggtatgtc ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa
     8281 aaggcgctaa aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta
     8341 tgaattatct tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt
     8401 aaatgtacat actcagtagc taggatggta acttattaca atttattgcg ataaaaataa
     8461 aagttgttat ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct
     8521 ataaaataag tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt
     8581 gtaataaaaa tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg
     8641 gatttgggcg gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa
     8701 aaagtgagaa tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt
     8761 aaaagtacag aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat
     8821 aataaacaaa atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa
     8881 aaaagatggt gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag
     8941 ccttctttca aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg
     9001 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
     9061 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
     9121 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
     9181 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
     9241 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
     9301 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
     9361 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
     9421 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
     9481 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
     9541 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
     9601 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
     9661 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
     9721 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
     9781 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
     9841 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
     9901 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     9961 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
    10021 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
    10081 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
    10141 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
    10201 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
    10261 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
    10321 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
    10381 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
    10441 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
    10501 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
    10561 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
    10621 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
    10681 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
    10741 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
    10801 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
    10861 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
    10921 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
    10981 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
    11041 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
    11101 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
    11161 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
    11221 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
    11281 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
    11341 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
    11401 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
    11461 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
    11521 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
    11581 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
    11641 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
    11701 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
    11761 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
    11821 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
    11881 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
    11941 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
    12001 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
    12061 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
    12121 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
    12181 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
    12241 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
    12301 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
    12361 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
    12421 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
    12481 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
    12541 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
    12601 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
    12661 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
    12721 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
    12781 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
    12841 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
    12901 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
    12961 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
    13021 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
    13081 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
    13141 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
    13201 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
    13261 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
    13321 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
    13381 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
    13441 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
    13501 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
    13561 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
    13621 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
    13681 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
    13741 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
    13801 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
    13861 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
    13921 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
    13981 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
    14041 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
    14101 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
    14161 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
    14221 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
    14281 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
    14341 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
    14401 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
    14461 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
    14521 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
    14581 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
    14641 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
    14701 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
    14761 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
    14821 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
    14881 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
    14941 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
    15001 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
    15061 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg
    15121 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
    15181 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
    15241 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
    15301 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
    15361 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
    15421 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
    15481 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
    15541 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
    15601 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
    15661 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
    15721 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
    15781 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
    15841 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
    15901 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
    15961 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
    16021 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
    16081 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
    16141 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
    16201 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
    16261 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
    16321 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
    16381 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
    16441 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
    16501 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
    16561 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
    16621 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
    16681 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
    16741 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
    16801 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
    16861 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
    16921 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
    16981 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
    17041 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
    17101 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
    17161 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
    17221 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
    17281 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
    17341 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
    17401 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
    17461 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
    17521 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
    17581 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
    17641 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
    17701 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
    17761 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
    17821 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
    17881 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
    17941 tatataagtc atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct
    18001 cataatcagt gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg
    18061 atatatgttt ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca
    18121 aagaactaac aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca
    18181 atacgatcga catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga
    18241 tgatcaatct agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag
    18301 catgtattga agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg
    18361 gttcgctgaa aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag
    18421 cagcaatcgc ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga
    18481 caaaagaaga tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc
    18541 gcttatccgg agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa
    18601 aagcaaagga agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg
    18661 ttttctccat ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat
    18721 atggactgat cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag
    18781 gaaccgtcaa gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga
    18841 aagctatagg tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga
    18901 aagctagaag tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg
    18961 cattggcttc gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa
    19021 atgctaatta ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa
    19081 cacctattac tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc
    19141 tgatcgaaca tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag
    19201 gcaggatcag aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag
    19261 cagtttatca aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt
    19321 ctatttaaaa ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta
    19381 aaaaagatca gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat
    19441 tggttcagag ttgatcacac ggctacgtca agaactaggc agtgaaaatg tcattgcgac
    19501 agatatacgc atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat
    19561 ggattacgaa aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt
    19621 ggctgctctt ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt
    19681 gactgggctg gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc
    19741 aagttcaatc ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct
    19801 tcagcgtcct acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta
    19861 ttattatgtg aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta
    19921 tgcaaccttg ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat
    19981 caaagaagga aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat
    20041 gccagatgcg atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca
    20101 tcgaaatgcc ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat
    20161 tcaaaaaatc ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat
    20221 agcagaatct tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc
    20281 gccgaaatac gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt
    20341 ggtagagacg gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg
    20401 ctatggtatg aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta
    20461 aaaatagaaa atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg
    20521 ggcacagtga tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga
    20581 tccgccagtt tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga
    20641 ctaacaggag ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc
    20701 gaacggattt acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat
    20761 tttccagcaa atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt
    20821 ggtctttccc agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg
    20881 atcaattttt taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag
    20941 cttattcctt tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc
    21001 caactgtttc cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc
    21061 ttgctagcaa cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa
    21121 ttgaaaaagc cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg
    21181 atcgtttatt tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca
    21241 ggaaacagca atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga
    21301 ctggtcacag ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact
    21361 ggaatgcgtc tcccttatgt tatggcaaaa gaaaacaacc tgccttttag caagctcttt
    21421 gctaaacttc atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc
    21481 gctattggca tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc
    21541 atttggattt tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct
    21601 gatttgtttc gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt
    21661 ggagggactt ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg
    21721 atagtattga cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa
    21781 cattcgaatt ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg
    21841 agtacgtgga agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt
    21901 ctacgatgaa atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac
    21961 tttgatttgc gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag
    22021 caaccagaaa tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac
    22081 aaagcatgtg gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg
    22141 aagactagca tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt
    22201 ctttttctta cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa
    22261 acaaagtaca tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa
    22321 gaaatgagaa ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga
    22381 gagatacaaa gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc
    22441 gctgattgtt tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata
    22501 tcgaaagtat ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta
    22561 tttattgtgt gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca
    22621 aatgacaggg ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa
    22681 cacggtattg gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt
    22741 tttggaacca gcttttaatg ttttattact cataccattt ggcatttatt taagatatta
    22801 tttccggctt tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga
    22861 attgacgcag ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt
    22921 gaatgattta gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt
    22981 tacatttatg cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac
    23041 tgtctcattg actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat
    23101 taatttggta gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca
    23161 tatctggtgg cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa
    23221 tggatggaca cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg
    23281 aatttcttta aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt
    23341 aagctggttg gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca
    23401 gatgagtgca gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa
    23461 tatcttgcta tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac
    23521 atatactgtt agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa
    23581 aaacgctttg tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg
    23641 aatgaataat tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa
    23701 gggcttcaaa cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa
    23761 aaatatcatt gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt
    23821 gtttgaaaaa atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag
    23881 ggaactagct gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga
    23941 gatccgtgtc tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca
    24001 tcaccaacag ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga
    24061 acaagcgctg aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt
    24121 ggatatgggt tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca
    24181 gtttttagtt ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat
    24241 ggaaaatcca atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa
    24301 ttggctgatt tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat
    24361 tggtcatcct tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc
    24421 cgattacttg aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag
    24481 agagagaaaa cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac
    24541 tgatttagct gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat
    24601 tccagaagat ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa
    24661 aggaacggcc attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa
    24721 attgggcgtc tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga
    24781 tcgtaataga cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg
    24841 tcttgtgaag aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc
    24901 aattgcagaa aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc
    24961 tcgtaaaaat aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt
    25021 cacaatctct tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc
    25081 aataaaaggt tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat
    25141 ttcagctact acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc
    25201 aagcaactga ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg
    25261 cttgaagcaa gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc
    25321 aagaaataga taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg
    25381 aatcccttgt tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca
    25441 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    25501 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    25561 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaaataa gtacgaaaag
    25621 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    25681 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    25741 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    25801 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    25861 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat
    25921 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    25981 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    26041 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    26101 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    26161 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    26221 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    26281 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    26341 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    26401 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    26461 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    26521 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    26581 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    26641 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    26701 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    26761 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    26821 gaacaagcat tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat
    26881 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    26941 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    27001 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    27061 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    27121 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    27181 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    27241 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    27301 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    27361 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    27421 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    27481 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    27541 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    27601 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    27661 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    27721 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    27781 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    27841 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    27901 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    27961 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    28021 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    28081 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    28141 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    28201 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    28261 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    28321 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    28381 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    28441 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    28501 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    28561 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    28621 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    28681 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    28741 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    28801 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    28861 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    28921 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    28981 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    29041 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    29101 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    29161 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    29221 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    29281 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    29341 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    29401 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    29461 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    29521 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    29581 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    29641 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    29701 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    29761 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    29821 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    29881 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    29941 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    30001 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    30061 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    30121 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    30181 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    30241 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    30301 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    30361 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    30421 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    30481 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    30541 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    30601 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    30661 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    30721 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    30781 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    30841 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    30901 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    30961 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    31021 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    31081 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    31141 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    31201 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    31261 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    31321 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    31381 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    31441 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    31501 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    31561 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    31621 atctattcat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    31681 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    31741 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    31801 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    31861 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    31921 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    31981 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    32041 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    32101 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    32161 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    32221 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    32281 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    32341 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    32401 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    32461 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    32521 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    32581 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    32641 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    32701 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    32761 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    32821 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    32881 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    32941 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    33001 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    33061 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    33121 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    33181 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    33241 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    33301 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    33361 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    33421 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    33481 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    33541 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    33601 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    33661 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    33721 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    33781 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    33841 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    33901 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    33961 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    34021 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    34081 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    34141 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    34201 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    34261 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    34321 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    34381 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    34441 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    34501 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    34561 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    34621 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    34681 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    34741 ccaaaacgga aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt
    34801 tgaagcgatg tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa
    34861 tcccgatggt aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa
    34921 ggattgattt tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc
    34981 agttggtcaa atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac
    35041 caggtatttt gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag
    35101 ggaagatgtg gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga
    35161 tgattaaaaa tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag
    35221 ctggtgcgat tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc
    35281 agacagattt tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag
    35341 tgatttgtat gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga
    35401 acttaaaacg acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt
    35461 caccgattac agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa
    35521 tggacagcca gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat
    35581 ccccgaacca gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga
    35641 agatgaagat gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg
    35701 tcatacgcat ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat
    35761 caacggcgtt attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct
    35821 aatggttgcc aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac
    35881 ctctttgcgc aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat
    35941 caatgcgcca atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg
    36001 gaagtcggct gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga
    36061 attaaaacta gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta
    36121 tccgttagct ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt
    36181 tctccatgcg caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga
    36241 agcacctctt ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt
    36301 ttaatttaga taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt
    36361 taagtttagt cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa
    36421 gtagattgct cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca
    36481 ttcctcctgt cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat
    36541 gcaagcaaaa gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta
    36601 tgagattatc gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg
    36661 aggaatctac attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat
    36721 tcctgtagga gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga
    36781 accggaactt cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat
    36841 tgatgatgtt ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt
    36901 tggcagacca agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc
    36961 aatccgtgca gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt
    37021 agagatgcaa gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag
    37081 gagagagaaa catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc
    37141 acgatcgccc aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt
    37201 tcggagcaac cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca
    37261 gttcaggact aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact
    37321 taggaagcag cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc
    37381 cagcgattgc acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca
    37441 tcaaaaagat cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag
    37501 tcatcatggt tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc
    37561 agggcacgta tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt
    37621 tcttcaacat gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta
    37681 gcggatacat cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg
    37741 cctggtttgc tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc
    37801 ttggagcaat cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc
    37861 atcttatggt attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata
    37921 agacgttgac aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg
    37981 taacaagtta cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg
    38041 tgatcggtgg agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt
    38101 tgattttaag tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa
    38161 ttgccgcaag tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa
    38221 atctgttgat tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag
    38281 gcacatttac attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta
    38341 tcttaccaga aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat
    38401 cagaacgtat cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta
    38461 tgggcttgat ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc
    38521 gccagtactt tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg
    38581 atgtagcgga gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg
    38641 tccaaaaagg ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg
    38701 tagcggttat ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa
    38761 tccagtgttc gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc
    38821 ttgatttgat gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg
    38881 taggtgatat cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag
    38941 gcgcacaagt attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg
    39001 gacattatat gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg
    39061 tgcaacacga acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac
    39121 atgggttaac agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag
    39181 caccagttaa ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga
    39241 tcgttcagca aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa
    39301 atggaaaagc gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga
    39361 tcaatacacg aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca
    39421 aagcaatcgg tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac
    39481 aattgatcac acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat
    39541 acaaggagac gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat
    39601 gcgcgatgcc gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg
    39661 acatcattag aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc
    39721 tgcgaagtga gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca
    39781 caaatgacgg tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg
    39841 caaaaaacaa taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg
    39901 ttatgcacgc tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg
    39961 agtcttctca aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg
    40021 tttgccatgt ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa
    40081 tccacgtaac agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg
    40141 aagatttcgg cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt
    40201 tgatcgaagg cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg
    40261 gattagaaga aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa
    40321 cagcgtttca actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag
    40381 tgatcaattg gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa
    40441 cggttggtgc ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata
    40501 aagaagactt tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg
    40561 aaacacaaat gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg
    40621 gaacgtttgc ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat
    40681 gctagtgtct tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc
    40741 actgatcaaa gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat
    40801 ggggtaaata gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa
    40861 gaacatgcac gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa
    40921 caaaaaggaa ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt
    40981 gaagtcggaa cgatgaaagc tagtatagtt gatgctggag attccttcga acatgcattt
    41041 gatcagctga aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa
    41101 ccttatccaa gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat
    41161 agtattttac gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca
    41221 gatgccgaga cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt
    41281 gatccaaaag atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg
    41341 atttttggta tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat
    41401 aaaatgaaat tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga
    41461 attgatttta cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa
    41521 aaactcatcg taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga
    41581 gattatcccg ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca
    41641 ctacatttat ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat
    41701 gccgaaacgt acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg
    41761 tcaagccgca gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg
    41821 atatgaagtg gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc
    41881 agatcaagta tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga
    41941 gcgtccagat gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga
    42001 gctggcagca tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc
    42061 tgcgatcgat caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca
    42121 gccaatcccc gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa
    42181 aatcggctat cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat
    42241 gtgtgaaaat gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc
    42301 tacccaatgt ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat
    42361 gagagattcg gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg
    42421 tatccataca ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata
    42481 tcaaatgctt cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg
    42541 taatgtccaa ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc
    42601 gcgtgtttct cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct
    42661 agctgctaaa atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac
    42721 gacttttgca gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc
    42781 gtttgataag tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga
    42841 agtgatggct atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga
    42901 aatcggtaca caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat
    42961 ccaaaaagtg gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag
    43021 agggtacacc atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa
    43081 actgttgcat atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat
    43141 attgaaaaca gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat
    43201 aaacgaagaa gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat
    43261 ggttgacact tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga
    43321 atatgaaaat gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc
    43381 tatccgtatc ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat
    43441 ccagcaggca ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga
    43501 cttttctatt tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt
    43561 gatcgagcta gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa
    43621 cttagccgaa cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt
    43681 ggatcgtgcg gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca
    43741 acctttaggg gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg
    43801 ttatccagtt cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga
    43861 aaaccagcga gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc
    43921 agtactagtg gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg
    43981 tgaaacagta ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg
    44041 ggattcaatg gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga
    44101 agattacacg atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt
    44161 tgtcatccat gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt
    44221 tccattctta agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt
    44281 gggagagaaa ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt
    44341 tcatgttaaa gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg
    44401 gcctgaaatg aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt
    44461 gtacaaggca ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac
    44521 gattgcggac gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg
    44581 ctatagtctg ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt
    44641 tgaaacagta gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag
    44701 agatggtaaa acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa
    44761 agacggtttc atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt
    44821 agacacagca gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat
    44881 ttaacggcga gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg
    44941 aaacaagaaa tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg
    45001 acattgaaag gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc
    45061 gtgccgcgtg cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa
    45121 acaaatactt gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact
    45181 ctttctgccg gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc
    45241 aatcttcata caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta
    45301 tatgagttat caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt
    45361 gccacacatg aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc
    45421 gctactgacg atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg
    45481 aagacggaac ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa
    45541 cagctgtttt cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg
    45601 ataggggctt gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt
    45661 gtgaaagttt gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga
    45721 atcctttagc ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg
    45781 gctgtttcgg ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga
    45841 tcatggtcaa ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg
    45901 aaacaccatc tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta
    45961 tgcataaact tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg
    46021 ctggtgcttg tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg
    46081 tgaaagcaat cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg
    46141 gaacagattc tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc
    46201 ctgtctatgt caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg
    46261 aagctggagg ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc
    46321 ttaagacaag aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca
    46381 agcctgtcgc tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg
    46441 ggatgggcgg cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg
    46501 ctgtagctat agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag
    46561 agctccctgt gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag
    46621 tgagagagga acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt
    46681 ttcaactagg caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt
    46741 tgtgaaaatc ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa
    46801 agaggctggt cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga
    46861 aaaagcaatg cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgg
    46921 cggtattcgt atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg
    46981 aaaacgtccg ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca
    47041 tgccgatcaa ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc
    47101 caaaaaagca ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga
    47161 aatggcagga gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc
    47221 aggagatcag acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat
    47281 cgttataggt cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca
    47341 aacagaatgg agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga
    47401 aattgaagca gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag
    47461 cccaatttac tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc
    47521 aaaaggatta gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac
    47581 tgcaacagca ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt
    47641 ctatattcga agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt
    47701 tgaaggtcag aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga
    47761 agcagctgaa gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac
    47821 gtatgagttg ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt
    47881 gaccaattat tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga
    47941 attaactctg ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt
    48001 gatgaagata gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc
    48061 caaaaactga ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat
    48121 cagtttttga tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata
    48181 atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt
    48241 tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg
    48301 gaaaaagaaa tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt
    48361 gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt
    48421 tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc
    48481 gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac
    48541 agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg
    48601 gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc
    48661 tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg
    48721 agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat
    48781 caaaaataac ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa
    48841 aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt
    48901 gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa
    48961 agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga
    49021 tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg
    49081 gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga
    49141 aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa
    49201 ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa
    49261 gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa
    49321 cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct
    49381 agttgtgggt gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa
    49441 tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc
    49501 ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc
    49561 aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt
    49621 cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat
    49681 ttattatttc gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta
    49741 gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt
    49801 tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat
    49861 cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg
    49921 gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg
    49981 atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc
    50041 aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa
    50101 gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt
    50161 atcagaagat atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg
    50221 catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa
    50281 ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat
    50341 gaagacctta tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact
    50401 ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga
    50461 gggattcgcg agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat
    50521 atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt
    50581 actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac
    50641 cgttgatcaa aaaagagggg ttgtgacaga attttgtcac aactcctctt tttgtagcaa
    50701 acaatttata actaattgct gttgtgggaa agtacgcaaa tatgattcta gaaacactca
    50761 ttgattacct gttttgtttc atagctgtaa ttttttcttc ttctggtgtc acgataatcg
    50821 tcttttggtt ttcataaata acataaccag gcttggcgcc atttggtttt cggatatgct
    50881 ttacctgtac aagatcaacc ggcacttggg cagagtatcg gtattttgaa aaataggcag
    50941 ctaactcggc agcttctgta attgtttcat ctgagggctt gtcactttta atgatgacgt
    51001 gcgaaccggg tatatttttt gcatgaagcc aatagtcggt ttttttagct gtcttcattg
    51061 tcagctggtc attttgaaga ttgtttttac caacaagaat gagcgttccg tcagaagaaa
    51121 agtattgatc aggctgagat ggtttcttac gtttttgttt ttttaagttc ttctttttca
    51181 ggtatccttc tgaagtcaat tcttctttaa ttgcttcgat atccattggg ccggcaattt
    51241 ccagttgaga taagacagat tcaagatatt ggatttcatc tttggcttct tggatttgtt
    51301 cgccaatcag cttaacagcg ttcttcagct tttggtatcg atggaaatat ttctgtgcat
    51361 tttgatttgg tgtcaatgcc ggatctagtg ctattttgat tggccgatct tcttcataat
    51421 aattaggtaa aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa gtagtaagta
    51481 gttcgccatt tctacggtaa ttctcagcgt tttcggattc tttgagtgtt tgttcacgtt
    51541 ttttcaattt atttttattt cgttttagtt cattttcgat ttttcgaatc agttctccgc
    51601 cttgttgttt tgcccgatct ttctctgctt tttcgtgata atagctatct aataattgac
    51661 tgagtgttgg ataagctgtt acagcagatg cctgttcgga caatacctga taagcaatcg
    51721 gtgtgaaaaa atctttattt tccgtttcgt aaaaagtagg aataggctga tggctgatgg
    51781 ctgagaaaaa ttcgtcccat acaaccatct tttcattagg acgttccagt aatcttttgg
    51841 tcagctcttg agcgatatcg aaaccgattc cctgaaactg acgttggatt gcttttggat
    51901 ctagttcagt ttgggaaagc cgctgaaaga ttttttcttt ctcggagcta aatgggttca
    51961 agacctcttg ttttggcgga gcaacatatt ctacaccagg aagcaaagaa cgataagtgt
    52021 tttgagagct tccaatgtgt ttgatcgcat ccagtatttt tccagtttct cgattaacta
    52081 agacgatcgt actatgacgt cccattaatt caacgatcaa tatgatattt tgtagatcac
    52141 ccaactcgtt tcgtttagca aagtggaaat ggatcactcg atcattttcg atttgttcga
    52201 tgtcttctaa aatagcgcca tccaaatatt ttcgaagcat catcacgaag ttaggcggat
    52261 tatcaggatt ctgataatcg atttgggtaa tctgtacacg agcataactt gggtgcgcag
    52321 ataataataa tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt tcattttcat
    52381 aaggctgatg gattttcgag atccggccag atagtaacgt ttcacgcaat tcgttgacca
    52441 tcgcgtgggt aaatacacca tcaaaggaca tggttcattc ctcatttctt ttcataagta
    52501 tattcattat aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa agcaaaagtc
    52561 tagaaaaatc ttggactaat tacataaaaa acagtgtttc tatcgttgaa atccaaattt
    52621 ttaggtataa taaaaaatag gagaaaaagt agaaaagaag gtgtttgtta tttgggaagt
    52681 agttaaatcg agagtacaag aaatgaatga acatttctca gtgtcattcg cagaaaatcc
    52741 aagtaagtat tttcgacgtc ttgtttttct gctcatctta tcattgctgt taacagttgc
    52801 aatgttttta ttgccggaaa aaatccgaga agagcaagta aatagtctcg tttattcgtc
    52861 cataccaacc agcaaattga aaccttttga ttacagcaaa gctgatcaga aaatcaaaca
    52921 aagccgggcg atatcggtga tgttcagcaa accgaacggg aaaacctatc aggacatgct
    52981 tgatgttttt aatgatcctg agcttatgga agaattgaat cgaccgatct tttattatcc
    53041 gatcgtttat gatgtacatg aactggaaca aaaatataac atacgaacgg atgaagtgac
    53101 atttattttc tttgatggag gaaaagaagc aaatcggata actgcgggta agggaggaat
    53161 aactgatttt gataaggagt tgatccctga actgaatcga cttccgttag ccaatatcaa
    53221 acaattagaa gaagaattgg atagaacggg agtaacttcc caaaattccg agattgctaa
    53281 ttgagacatt ggcgcgatga aacggtgggt ctatatagcg ctatttttaa ttatcagaac
    53341 aagtgatgtt tgatcttcaa aataacaaat aaaaaattaa aaaatatagt tgacgaaatt
    53401 caaaaattcg atttgactta aatcaattct taaggaaagg gtgacctgta atgaacttat
    53461 caaaacgtat ttcagcagaa aacaaaaaaa attggcgcag ctggcgtaga taagttgtat
    53521 taatggtgag actttcccat agatacaact ttttagagtg catttctaaa gcttgtatct
    53581 atgctagaca tgaacattga ctgccgcata gattagaatc tatgcggttt tttgtgtaaa
    53641 gacaatgacc gctttggcca ttgtcttttt ttgtagactg gatacttgcc tgattataat
    53701 aaataaaaag attgactttg caggaggaaa aaaatgaaaa acaaacgatt aataacagtt
    53761 gtagtaatta ttttagttta tttagcaggt gcatttattt atggaaaagc ctcaggcgaa
    53821 aaagaaagta cttcgacgaa ccagacaaaa aaaacaacag ttgttggggt attgcaatac
    53881 gtgagccatc cggcattaga tgagatttat cgaggaatca aagatggtct gaaagaagaa
    53941 ggattaaaag aaggagaaaa tcttgagatc aaatttcaaa atggacaagc cgatcagagc
    54001 aagctagcca caatgagtca acagctagta caatctgatc cagatgcctt gattggaatc
    54061 gcaacacctg ccgctcaatc attagcaaac acgacttcat cgatcccagt tgtgttaggt
    54121 gctgtaacgg atcctgtggg ggctggatta gtcgcttctt tagagaaacc tggtggtaat
    54181 gtaacaggtg tttctgatca gccgcctgtt acttcacaaa tcaagcttgc ttctgatttg
    54241 ttgccaaatg caaaaaaagt cggaatcttg tatgcttctt cagaggataa ttcaaaatac
    54301 caagtagcac aagcagaaga agctgcaaaa aaagaagggt tagaatcagt aaaatatgcg
    54361 gtgccttcca ctaatgagat tgcacaaacg gttcaagtga tgagccgaca agtcgatttt
    54421 atctatgttc cattagataa taccattgcc aatgcgatgc aaacagtggt aaaagaagca
    54481 aacaaagcaa atatccccgt cattccatct gtggatacaa tggtggaaca aggtggacta
    54541 gcaacaatcg ggatcaatca atatcaatta gggcttcaaa gcggtaagat ggcggcagaa
    54601 cttgcgagtg gaaaagaaaa accggaaacg acgcctgttt atacatttga tcaaggggat
    54661 acagtgatca atcaatctca agctgatcgc ttaggaatca ttgttcccca atcgatgaag
    54721 gaaaaagcca aaatcattac agatgactcg cagcaagaaa catctaagga ggatgacaaa
    54781 tgatcgtatc agctatttca caaggcatgc tttgggcaat attaggatta gggattttca
    54841 tgacttatcg gatcttagac tttcctgata tgacgacaga agggtccttc ccattaggtg
    54901 ctgctgtctg tgtgacagct attactcatg gggtagcgcc gattgtagct acattattag
    54961 gcgtaggtgc tggcatgata gcaggactcg ttacggggtt actttataca aaaggaaaga
    55021 taccggttat tttagcaggg attttagtga tgtcaggatt gaactcagtt attttgtttg
    55081 tgatgcgaac accaaatctt tctttattga atcatccgat tctacaagac agcttccatc
    55141 gctttgggtt acctgattac tttgacacag tccttcttgg cttcatctct ttgggcatct
    55201 tgattgctgt actgctattc ttcttcaata cagatttggg tcaaggctat attgcgacag
    55261 gagacaacga aacgatggct cggtcgttag ggataaaaac cgatcgtatg aaaattttag
    55321 gtttaacttt gtcgaacggt gtcattgcat tatccggtgc gctgattgcc cagaacgacg
    55381 gatatgcaga tgtaaataaa gggattggcg taatcgtcat cggtcttgct tccatcatca
    55441 tcggtgaagt gatcttccaa gaattgacgc tagcagaaag attgattgct attgttgtcg
    55501 gcagtatcat ttatcagcta ttgattttag tagtaatcaa actagggttt gacacgactt
    55561 atctgaagtt gttctccgct atcatcttag ctatttgtct gatgatcccg caattgaaga
    55621 aagcactgaa cttaaaaacg ggttttgaga aggaggcata gtaatgactg atatattgac
    55681 aatcaaaaat ggcagaaaag tcgtaaacaa tggaatgaat gaagagaaag tactattgga
    55741 tgaaattaac cttacaatca gagaagggga cttcatcact gtccttggcg ggaatggtgc
    55801 tggaaaaagc acactgttca atacgatcgc tggtacgctt caactcagtc aaggatcgat
    55861 ctcttttaaa gatcagctga tcacaaaaga ttcagaagaa aaaagagcac gattcctttc
    55921 tcgagttttc caagacccca agatgggaac ggctcctcgg atgacagtag cagaaaattt
    55981 gctacttgca caaaaaagag gtcaaaaacg gaaattccgt ttacgtaact tgaaaaatca
    56041 aaaagaagat tttttcagac tatgtcaaga agtcggtaat ggcctagagc aacacttgga
    56101 tactccagcg ggtgaattat ctggtggtca acgccaagca ttaagcttgc tgatggcgac
    56161 gatcacagct cctgagttac tattattaga tgaacatact gcagctttag atcctaaaac
    56221 agctaaagca ttaatgcgat taacaaatca gcggatcaat gaacaaaaat tgacttgtct
    56281 catgatcacg catcgaatgg aagacgcctt gaaatacgga aatcgtctga tcgtactcca
    56341 aaaagggaaa atcgttcaag atatttctga aaaagaaaag caacatttga caatgggcga
    56401 ccttttgcag ttctttgaag aagtagtgga ttgatttcga cagaaaaatt cctttcagta
    56461 gaaggacttg aaaactcatt gacatcttcc tttgattcat cctatactta aaacaataaa
    56521 caattaaaca tatttgggtg ttttgtagga tcacgtagtc aatgatttta acaattaaat
    56581 agaatattct ttgctctgac aagtaaacga tgagaaaaga atttgctact ttgccaccta
    56641 gacgtttcgt actttttcgt atcaaacgct aagtggcttt ttttattgaa gtaagaacaa
    56701 aggaggaata agatgatttc tggacaaacc aaattagctg ggctctttgc tgatccggct
    56761 tctcacagtt tatccccatt gatgcacaat actgcttttg aagcaaacaa catcgatgcg
    56821 gtgtatttag ctttccaagt aaatccaatg aatttgaagc aagcagtcga aagtattcga
    56881 acttttgata tgttaggtgt aaatctttcg atgccgaata aaacagcggt tattccttat
    56941 ctggatgagg taagccagga agcgcaattg atcggagcag tgaatacgat cgtgcacgaa
    57001 aagggtcgtt tgattggcta taatactgat ggtgcgggct tcatgcaatc cgtgcaagaa
    57061 gctgggattt cgatcaaaaa gaaaaaaatg actctactgg gagctggagg tgcagcaaag
    57121 gcagtcactg ttcaagcagc gttagacggc gctgaggaaa tcgtagttta taaacgaaac
    57181 aaccaaacat tcgctcaagt aaaagaaaca ttcgaacaac tcagctatcg aacttcttgt
    57241 aagataaaag ttcgtgactt tgccgatacg catcaattaa gaaaagactt gaaagaaagc
    57301 tgtcttctag tcaatgcaac agatatcggg atgggaaaga aaatcaatca gtcaccgctc
    57361 ttagatataa gcatgatgca tgagaatcta gcggtttttg atttgattta tgcacctaga
    57421 gaaacacgtt tattaaaaga agcaaaaaaa gtaggagcaa aaggatacaa tggacttggc
    57481 atgttgatct accaaggagc aatcgcgttt gaattatgga caaaggaaaa gatgccgatc
    57541 catgtgattg aaaagctgtt tgattaaaaa aggataatag ataaagatct tttattctcg
    57601 cataaacggt ctcaagaaaa gtaatccttt atgtatcgaa gcatttattt cgttattttt
    57661 tattaaatta tcaaaaaatg ataggctttt gtcgattggt tatcgtatcc tttatttatc
    57721 agtaagaaac gaggaggaac cacaatgagt cggatggatc gctataagga catccataag
    57781 aaggcgaaac ctctgaagcg ggatacgggg agtatttttg ctagaagaga acgaaaacga
    57841 acgcgtatgg aaaatgagga agatgctacc cgtatttatg aaagagagca gcattcattt
    57901 gaacatttga accaatacga gcaacagata tacagagatg caccaagagc agaagaacaa
    57961 caaaaaaata aaaaattttt caatcggcaa aagaagaaca aaccgttaaa acctcgaaga
    58021 aagcgatcgt ggaaaaaaat cattctatcg attttgcttg ttttgatcct ttattcaggt
    58081 atctcatttt ttattggtaa atatgtagct gaacatgaca caagcttaga ggcagcgact
    58141 tcagaaacct ttcatgggca aaaagcgacg aatggtgcgc ataatatttt gatccttgga
    58201 agtgatacac gcggagaaga tgccgggcga gccgatacga tcatggtctt acagttggat
    58261 ggtccttccc ataagccgaa actgatttct tttatgcgtg acagcttcgt tacgatccca
    58321 ggggtaggac aaaataagat caattcagct tatgcatacg gaggagccga tctagtgcgt
    58381 caaactttag tagaaaattt tggaatcgat tgtcaatact atgcgaaagt cgatttcaaa
    58441 tcgtttgaaa aagtgatcga tgccttattc atgaacggag tgaagatcga tgcagaaaaa
    58501 gatctgaatc tggatggtgt agatattaaa aaagggggcc agaagatgga tggacatgtt
    58561 cttttgcagt acgcacgttt ccgaatggat gaacaaggag actttggccg tgtcagacgc
    58621 caacagcaag taatgaacgc tattttcagc caattgaaga atccattgaa tctgatccgt
    58681 gcaccttatg cagctggtaa agctttagga tatacatcca cagatgtcac tgcttggttc
    58741 ttgacgaaaa acctcttttc gattgcacga ggagctggtg gcattgatcg aataagtgtg
    58801 ccagtagacg gttcgtggaa ttatgggcaa agtgattatg ctggcagtat tcttgaaatt
    58861 gataatcaaa tgaatcaatc tgctattaca gattttttga ataaatgatc ataaaaaaga
    58921 tcaagaagaa gctgcgcaag gcttttgtca tgaatcaatc aaacgattca ctcgtaaaaa
    58981 acgctttctt atggtagatt taaccaagag aggagctgtt tacattggat atctatctga
    59041 acttcaaaaa tgagtcgcgt gaagccatcg ctttttatga aaaagttttt cagactgaag
    59101 catcaggtat caccacatac ggtgaaatgc ctggaataga acaaatgaac ttgccagaag
    59161 aagcaaaaaa tctaatcacg aatgcacggc tgaacattta tgatacatta gttatgtttg
    59221 cagatacgcc agaaggaatt ggtcctgaat tagttgtggg aaataatgtt tctttagtca
    59281 tccagacaag aaatgaagaa gaaacgaagc gcctatttga aagcttagct gagggtggta
    59341 agattgagat gccactggat gctgttccgt gggctcagtt gtatgggatg gtaactgatc
    59401 gatttggcat caactggcag attaaccaag agtgacagct aaagatgaat attttctgga
    59461 aacatcaagc agcaaacgga tcatcgtttg tttgcttgat gtttttgtgt ctatttcgac
    59521 tatacggtat ctttttttta ttgccagatg cgaaaatatg ttccataata gagaagtccg
    59581 caaaaaatta agtaacggag gtcagaagat gaagacggtg atactagctg aaaaaccttc
    59641 acaagcaaaa gcctatgccg aaaccttcca acagcaaaag cggcatgaag ggtattatga
    59701 aatcagcgat ccattgtttg ctggtgaagt aaccatcact tatggttttg gaaatttggt
    59761 agatatggtt gctccaggag cttatgaaga gcgttgggca aaatggtctt tagaaaattt
    59821 gcctattttc ccagaaacct tccgttacga agttccaatg gacaaacgtg cacaattttc
    59881 gatcgtaaaa cgagaattgc agtcagccga taccatcatt attgcaacag atggtgatcg
    59941 agaaggtgaa gccatcgcgt ggtcgattat tcgacaagca aacgcatttt ctaaggaaaa
    60001 gaactattta cgtttatgga tcaattctct tgaaaaagaa gcaatctatg aaggttttaa
    60061 gaatctccaa cctggaaaga actattttcc aaaatataaa gaagcgcaag caaggcagaa
    60121 cgctgattgg ctgattggaa tgaatggaag tccattatat agcttgctac ttcaacgaaa
    60181 agggattgat ggcagttttt ctcttggtcg tgtacaaaca ccgacactct atatgattta
    60241 tcagctgcaa gaagaaatca aacacttcaa aaaagaaacg tactttgaag gagaaggttt
    60301 aattacgaca aacaaagggc agttttctgg aaaaatcgta ccaaaaaaag catttaaaac
    60361 ccaagaagag ttaacgaagg aaatagaaaa acttggagcg catttaggta agcaaaacgg
    60421 acggattctt gaagttacga aaaaggaaaa gaggttgcat agtccacgtt tattttcgct
    60481 atctagtttg cagacaaaga tgaatcagct aatgaaagca agtgccaaag ctacacttga
    60541 tgctgctcaa ggattgtacg aaagcaagtt tctaagctat ccaagaacgg attcctttta
    60601 cattacagaa aatgagcatc agtatctggt taaacatctg caaaattata aaaaattttt
    60661 aggaatagaa gaagtacaga caactgagat caaagcaaag aaacgatatg tcgatgcgaa
    60721 aaaagttcaa gaacatcatg caattattcc gacaaagacg attccgactc ctgcacgctt
    60781 tgcgaagctt tccaaattac agcaagcaat ctatttgcaa gttttgcgca ctactgtggc
    60841 tatgtttgct gcagattata tctacgaaga gacgaccgta atgacgggcg tacagcaatt
    60901 aaagctaaaa agcatcggaa agatcccatt acagcaaggt tggcaggaaa tcttacgcat
    60961 caagtcaaaa aagaaagaag ctcagactct tcctcctatc gtagaaaatg aagaagcaga
    61021 agtagaactg aaaagtatgg agaaagaaac acaacctcca aaaccctata ccgaaggaac
    61081 gttgatcaca gcaatgaaaa ctgcgggaaa aacgctggat aatgatgaag cgcaagaaat
    61141 tctcaaagaa gtagaaggaa tagggacaga agctacacga gccaatatca ttgaaaatct
    61201 taagcagaag cattacatcg aagtcaataa aaacgaaata actgttacgc caaaaggaat
    61261 cactctttgt aaggcagtag ccaatgaacc attactgacg agcgcagaaa tgactgcgcg
    61321 ctgggaaggg tacttgagaa aaattggtaa acaagagggg acaccatctg tttttttaga
    61381 gaatatcaaa aaattcatcc tacatttatt ggcagaagtt cctaatcaaa tcgacaaggt
    61441 agacttttca gatgagatta gcgggacacg tcagataaaa gcgatggaga agaaaaacga
    61501 tcaattagga agatgtccaa aatgtaaaaa gggaatagtc atgctttatc ctaaaatcgc
    61561 tacatgcttg aatccggaat gcgacttcaa attgtggcca acagtagcta aaaagaagct
    61621 gactaaaacg aatctcagag atttgctttc aaaaggaaag acaagtaaag ttgtcaaagg
    61681 ttttactggt aaaaaaggga aattcgatgc agttttagta ttaaaagaag atatgacaat
    61741 cggtttttct tttccatgga tcgaaaacag tggaacaaaa gcagttgatg gaaacaaaga
    61801 aacatcaaga aaaaataatg aaaacgaagt agagtaaatg aaaacaatga aatagcggaa
    61861 tatttattcc gaaaagtgag aatataaata ccaataaaac taaaaaatat cagtgaatca
    61921 agcaaaaacg ttggggtagg ctgattttat atagatagca aggagttttt ttatttgaaa
    61981 aaagtgcatt catttttaaa ttatcttatg ggagcaatca cgattgtggc tgtgtaccaa
    62041 gcatttctaa agtatcctga ttacgggacg aagttgttgt cattgacgca caatcaaaca
    62101 gcatattcac caacgttgat tttatcgact ttgactgcag gagctaaaag cgctacttat
    62161 ttttttcata aaacgacaag catgctaaag cgaaagaaac agcgaaaaca attgttggtg
    62221 gtggtagcgg ctatgatcat tatttatttt ctaccagtta ttacacaagt atttcatcaa
    62281 tattttggtt aagaatacga gagtttgtga caaaagtcat gtcacaaact tttttctttg
    62341 tcattttttc gtaagaaaaa gcaaaataaa agtatataca ttgattaaaa gtatatactt
    62401 ggatataatg tacttactat agaatgagaa tggtatagag ggtggcgaaa tatgaaaaaa
    62461 atgaaaaagt ataaaattag aaaatctggc aatagcgatg taacaactat cccaccagaa
    62521 gtaaaagaat tcatgggtgt gcagacaggt gacgcaatca gttatgtttt tcaatctgat
    62581 ggttctgtac gaatgatcaa agcacaagaa gaacctgata ttgattcatt agttgattcg
    62641 atcatgaatc aatatgaaga cgcgttaaaa gatttggttg atttatgagg tatctttcga
    62701 ctaaagaaat tatcaaaatc aacgcgaaag ttattttacg tcactcgcca ggcgaaatga
    62761 tcggtgtaaa agatgcaaat gcattagata tggccgtcaa acagccttca caagcagtat
    62821 tcaatcaaga actctatcct gaaatctatg aaaaagcggc gattttagca attaatttag
    62881 ctaaaaaaca tccttttcat aatggcaata aacgaactgc tcttgttgcc atgttgttgt
    62941 ttcttcaatt gaataattgt ccagttgctt tttctcgtca agaagctgtt gattttatca
    63001 taatgattac cactagttca ttggatttcg attcactaaa gtccaagata accagttatt
    63061 tacgacaaac cgcaataaaa tgaacgaatt aaaaacttta tttctcaatt agatcagcat
    63121 gtcattaagg aatatgctga tttttttatg tttaatcata caaaatagtt ttttcataaa
    63181 aatatggaaa atatggatta attttgaaat aattgattta aaaggaatac aaaagagtga
    63241 atagtaggaa atagtggttt agaactagtg ggctgatttt ttatatattt tagtttacat
    63301 aatatatatt atacaaagta gatttaaaaa atgataaacc tctctcgaac ggttttttat
    63361 caaaaatcgt catttttcca tcaaaatctg cttatgcaaa attataaaaa aattttgcag
    63421 tttttcttac tttttttgtc gtttaattga atgataaaaa ccagtttctt tattcagtta
    63481 atcaaatatg aacgaattag atatgaatca ttgtatttgc cgttgcggaa ggatttttta
    63541 attaaccaca gataaacatt gataacgatt cgcttattgt aatcaacaga ttaaatttca
    63601 tatgttcata tgtacggata cattttcgga ccgattaatt ttaaccattc tgtttatttg
    63661 cttacctatt agatatcaat aaaaaactgc ttaacagcta tttcagctgt taagcagttt
    63721 taggattttt agttcatatt cattgtttct tataatacag tgttcaatac ttctcttaaa
    63781 gcacttgttg atttgctgaa cattgctttt tcttcttcgt tgattgataa ttcaacaact
    63841 tcacgaacac cattttcgtc aacgattgat ggcacacctg taaagatatc tttttcgtcg
    63901 tattcaccag ttaaataagc agatacaggc aatacagctt gttcgttatt caagatagct
    63961 tttacgatac gtgcagtact cataccaata ccataataag ttgctttttt acgatcaatg
    64021 atctcataag cagcattacg gactttatca gcaatcacat ctaattcatc ttgggcaata
    64081 cgatggtctt tttctacaat ttcaaacact ggtttaccac cgacagttgt atgtgaccat
    64141 gcagcaactt ctgaatcacc atgttcacct aagatatagc cgtggacgct gcgtgggtca
    64201 acttttaatt tcaatgcgat ttctttacgg aaacgagttg tatccaatgt tgttccagta
    64261 ccgataacac gtgatgttgg cagaccagat tcgttccaag cgatatatgt caaaatatct
    64321 actgggtttg aagcaacaac gataataccg tcgaatcctg atcccatgat ttcttttacg
    64381 atttggcgca tgattgacgc atttgtttta actaaatcta aacgagattg accaggtttt
    64441 tggttgatac cagctgtgat aacaacgata tcagcatctt tacattcttc atagccacct
    64501 gaccatacag ccacattttc atcgccccaa gccataccat ctaaaaggtc caatgcttcc
    64561 ccttctgctt tttcttgatt cacatcgatc aatactaatt cattagagat tccttggttg
    64621 atcattgcat aagcgatact tgttccaaca aaacctgtac cgacgattac tactttacga
    64681 cttgtttttt tcatgaataa acagctcctt ttcataacta tttgttactt tcatgaaaag
    64741 tatagtcttg tttattcatt ttatcaacat gttaattata atagttgtta ttataatttt
    64801 tgatggaaac gaattcctga atacgcataa cagataaatg acaaatgttt acacctatat
    64861 cccctgataa tacaaccaaa agtttagaac tgaaaataaa tccaaaaaaa ttcgctgcaa
    64921 cgatataata agacagcaat cgcacctaaa acaattttcc ttcatatgct ttagtgaaag
    64981 attttcttct taatgtttat ttctccattc attgggagta catgttgaat acttcttgaa
    65041 taatttgaat aaagaagtcg tttgtttata tccgatacga ttagcgattt cttccaacga
    65101 aaaactcgtt tcttgaatca gttccaacgc aaagtcgaat tttttcttta gaaccagttc
    65161 ttgaaaggaa gcatcaaaat acattttcaa tttattacta agatagaccg gattgtagcc
    65221 aaaatgagct gctgtttctt ttaacgtaca agaagtaaaa tgcttatcga tataatctaa
    65281 tactctaagc atctcatttt ctgcgcatcc atctgctgat gaaaagcttt gttgttctaa
    65341 taaatgagtc aattcgatca gtaatagtga tgtatagaga tttaacgaac ggatcttatg
    65401 actgtatgta tcaaaataaa tcaacagcat attttcaatc aaatgcgtca aacgacttgt
    65461 ttttccgccg cgaaaatgaa tgaattgtgt atgttcccct ttttcttttg atgcatttat
    65521 caaaaaagaa gaaagtagat tatttgtgct tgccaaatga ttcaatatct ctgtagataa
    65581 ggtttcttct tttaataaga tgttgattaa aatatcctct tgccctgtgt attcgattct
    65641 ttgagtagct tctttatcaa tgatcaccac gtcactttct tccatctcta tcctttctcc
    65701 attaataatt tgtaaacatg taccgctata catataattg atttcaacaa aatcatgtgt
    65761 atgctcggga acttccgcat atcgacggtg tttactgata tgaatatttc cctgttgaaa
    65821 tagatcccct cggtggattt ttggcggtgt ctgaagatgg taagctaagt ttaaatcatt
    65881 gatattcatt ccttgttcac gctgcagagt ttcgattgat tcttcgttac gcaaaaaaaa
    65941 tgtctaattc agctagttcc aattgactcc ctcctttttg taagcggttt ctttcgctta
    66001 ttagttcacg ctgtactgct attatatgca aagctatttt tggtttcata aagactttct
    66061 atggttggga catgaacttc ctgtgattcc gctattgaga gaataaccac ttcatactat
    66121 atttttgata agcgcttaca aaaatgaaag gaacatgctt atgaataaaa agatgatgaa
    66181 attttctctg ctgtcagtct ctcttatttt gacttctgct ggtgcagtca cgtctgcaat
    66241 tcccagtatg tcagctactt atgccacgcg ttctttatct gctgttgaat tattaacgac
    66301 tgctccctct tttatggtca ctatttttgt tttgattagt agttttattg ctaggaaaat
    66361 cggacaaaaa caaactgtga tcatcggatt agtgattgca tcgatttgtg gtatcctccc
    66421 cctcttctca caaagttaca gtattgtctt agcttcaaga gctggactag gtattggctt
    66481 tggattgatc aattctttgg cagtcagcat gattgctgcc ttttatcacg gagatgaacg
    66541 agcctctatg attggttttc aaagtgcatt tcaaggattt ggtgcagctt taatgacatt
    66601 tgttgcagga cagctagtac agttcggttg gcaatatacc tttttagtct acgccatcag
    66661 cttacctatt cttgtcttgt ttgttttgtt tgttcctaca cctgaaacaa ctgaacttca
    66721 atcgcatggc acagccccaa caagacaagt aatcaaaacg aatcctaaaa tgattagtta
    66781 tggtattttt ctcttgctgg tcatcgtggt atataatgct gtatcgatta aattagccac
    66841 agtcctgacg acttattctc taggaaacga aactaatgca gcgaatatct taacaatcat
    66901 gcaattggca agtatggctg ccggagtttg ttttggctgg cttcagacaa aagcacatcg
    66961 ctatatgctt acactttctt tactactgat gggaatcggc tttgtattga ttgccactgt
    67021 gataaacctg tatgtgattg ggtttggtgc gatcctaaca ggaatttctt tttcgttatt
    67081 cattccttac ttattcaacc aagtaagtat ccaagcgccc aagtacgcgg agagtttcaa
    67141 tacttcaatc ttattggttg gcgctaattt aggtactttc attgcaccat atggtttgct
    67201 ctttctctct tttgcttctc ttgggagtaa aacacttgct gttttcgtca atggcagtat
    67261 cttgctgttg attagcgcgc ttattagcct tctagtagta cacaggacga atagaaagac
    67321 agtgataaga gtagatgaag aaataaaaga acaattgaca acaaaataaa tttgatggag
    67381 gtcgtgtaaa atgacaaatg aaaaacataa agatagatgg ctttggtatc ctggagactt
    67441 tgagatccgc catggactgc tacaaaattt ccaacgggaa gaacgaggtt ttgactggcc
    67501 agcgtactgg tacatggatg attgccatcg gaacgtcaag tttaagagat attactttct
    67561 tgatcaacct tccatgttta aagtgacgat ccaaggagtt gggtatgtag aaattaatgg
    67621 acaaaaacat ccatgtggaa aatggctgac ttgtccagct ggtaaagcaa aaattcgtat
    67681 ctttgtagga catacatcag ggctaccagc gatgtttatc gagggagacg aagtaaaatc
    67741 agatattggc tggacagcaa gtaattttat tgaagaatat ccagctggct ggagtccgct
    67801 ttatgtcgat atcgcaaaag atccaaatca aatctattat caaaaagaat gcgtccatcc
    67861 agtcactgaa acggagattg gcggaggaat cttattcgat tttgggcgag cagtgaatgg
    67921 ctgtgtagaa ctaatatctc tggatgacca tatcgaatct atcactctat gttatggaga
    67981 gtccgatgta gaagctatgg atatcgatta ttgctactat aagcaaatag gaatgacaag
    68041 aaaaatgaaa gctcgtaaac gcgcttttcg ctatttgttt ataccagagg tttctactgg
    68101 aatggttcaa cttcaagttt ttcatgaatt tttatctctt tcgaaacaag ctgctttttc
    68161 aagcgattct tctttactga atcagatctg gtcagtatca gaagaagcct tcaagttatg
    68221 tagtgatttg ttttttatcg acggtatcaa acgagatcgc tggatttggt ctggagatgc
    68281 gtatcaatca ttcatgatca atcaatatct tttttttgac gaggaaatca ataaacgaac
    68341 gatattagca ttaagaggac aaaatgaaat caagcagcat atgaatacta tcgttgacta
    68401 ttcgatcttg tggttgattg gtatcgaaaa ccactatatg atgacgaaag actatgaatt
    68461 tttacgcatc gtctacccta agatgcaatc attaatgaga tacttgatgg agcaaacgaa
    68521 tgaattaggg tttatttatg ggagagcaaa agattggata tttattgatt ggtctgaaat
    68581 ggataaagaa ggaacgcttg ctgcagaaca agtcttatta ctgaaagcct atcattccat
    68641 gatcacttgc ggagatatct tagctgaaac atatggagag aacgaaaatt atcatactca
    68701 tctctatcaa gaaaaatatc aactattgaa acaaaaccta tttgactact tttgggatga
    68761 agaacttggc gcttttatcg attgctatga atctgggaga agaaatgtga cgcgtcatgc
    68821 gaatattttc gctgttttat tcgattttgc taacaaagac caacagcaat cgatcttaaa
    68881 gaatgtctta ttgaatgaca ctatcacaca gattactact ccatatttca aattctatga
    68941 acaagatgct ttatgcaaac tcggacagac gaatatcgtc taccaaacga ttcttgatta
    69001 ttggggaggg atgttatctc atgatgcggt aactttctgg gaagaatacg accctactca
    69061 aacaggaaat gaaaagtaca gtatgtatgg agatccttat ggaaaaagct tatgccatgc
    69121 atggggagca agcccaatct atcttttagg acgctatttt atcggtttgt atccaacaaa
    69181 gccaggttat gaagaattta tgatacaacc taatctagat tcatttgaaa cactgaattg
    69241 tacgctacct atcaaagatg gaaagatttc gcttgaaaaa acaaaagata agatcgtgat
    69301 tacttctgat agaacaggcg gaacagtgaa aatgaatggt aaaagttatc ctcttctagc
    69361 aaaacagcca cttgtcttaa caagctattc aaaaataaat gcataaaaca aaaaactgct
    69421 tgcgacatat cagaagactt taaatcttct tctgatattg tccaagcaat ttttattttg
    69481 aagtttgctt aattctgttc tttagaaaca atgtttgttc tttttccggc aaaaagaaag
    69541 ctagataata cgacaagtaa aaagaaagcg atgattccaa ctgtcaaggc tatttgaccg
    69601 tattctccta gtttcccaag tacaagtcct ggtactagat aatcagtatc ggcaaatgta
    69661 gaagaagcga ttttaagatc tcctaatact ggaaggataa ataatggcag ccaactaatc
    69721 aataagctat tgaaagcaga acctaatacc gcccctcttc taccgccagt cgagttgccg
    69781 aagacaccag aagcagctcc gcagaagaaa tgtcctacta ccccaggaat gataactgta
    69841 gtttgcaagc ctatcatagc aaacatggat agtgttccta caaagaagct aacaaaaaag
    69901 ccaattaata cagcattagg tgcatatgga aaaacgatag gaacatctaa tgctggttta
    69961 gaatcgggta cgagtttttt agcaatccct tggaatgctg gaacgatttc tgccaacacc
    70021 attcgaaccc cttgaaggac gataacaaac ccagctgtga atgttccagc ttggatcagt
    70081 gcaaagatta cagcgttgtc tccattgctt agttctcttt caacaaatcc aggaccagct
    70141 aacaaagcaa gtgcgacata tacgatcgac atcaagagca tgatcgatac agtagaatct
    70201 cgcaaaaagc tgaaactttt aggaatcttt atgtcctctg tagaacggtc tttgtttcca
    70261 aaaaactttc cgatccatcc actagaagca taaccgatat ttccggtatg ccctaacgca
    70321 acttgattgt ttccagtgat gttcttcata aacggttgac aaagagcagg cgtaatagtt
    70381 aatagtgttc cttcgaagac cccgcctaat aagatcatcc acaaatttgc agtaaacccc
    70441 gcgcttacta aaatgactgc tgttagacaa gaaacataaa gcattgcttg acctgtaaga
    70501 aaaatgaatt tatatcttgt gaatctagca agtaaaatat tcacgatcat ccctactagc
    70561 atgatcaaag cagtaggtgt accgtattgt tgcaaagcaa tcgccactac tgcttcattg
    70621 ctaggaacta ctccttgagt atgcagagct gtttggaaca tcgaagcaaa aggggttagt
    70681 gaattactga ttaaaccagc accgccgatc agtactagga atccgacaaa tgttttgata
    70741 gttccttgga tcacttctga aaatttcttc ttctgaagaa cgagaccaag cagtgcaatc
    70801 aaagaaacga ggatggaggg ctgactgacg attgacacaa acaaattcaa caatttatcc
    70861 attgatagtt cctcccttga atcattttta ttcttttgac aagatcttcg ttactttttc
    70921 ttttacttct tcgctgtcaa tgatcgattg caaaggtacg agcttttcat caggtataga
    70981 agttagcgta tctttcaaag aatgctcaat gaagaaataa tcagccatat cgctagatac
    71041 acttccaaca tccgtatgac ttacttcaaa ctcgtccaca tctgctccaa gatctgcaag
    71101 tgcttgtttg atgttcatct ctaccataaa acttgttcct aatccacttt gacatactgc
    71161 aaaaattttc atatcattcg tctccttttc ttatgatcgc taatatttct tcttttgttg
    71221 atgcgtgtaa taaatcttga agattttgtt tattagaaag tagctttgtt aaatttgcca
    71281 aagcccgaag atgtgcctca ttatcgatag cagctaaaca gatgaacaaa ctaatgggat
    71341 gggctggatt atcaagcaga tccacaggtt gttgaagttt cagcaaagac atccctactt
    71401 cgtttacgcc atcttctgga cgagcatgag gtaatgcgat gtgatcgcca atatggataa
    71461 acgcaccata ctgctccacg cgctcgatca tagctttgat ataactttct tctattttat
    71521 tttctgataa tagcggctgt gcggcaaatg tgattgcttc ttgccagttt tttggttgat
    71581 ccgataattg gatcatttct tctgttaata attcagatag cataggacgt tgatcctcct
    71641 tcttttctaa aagtttgttc attttacgat ttaatacttg atagagcttt tcttcgtcta
    71701 cgccttcttt taattcgata taaggcagta gcgccgacaa caattcttgg gcagaaggca
    71761 ttgaaaatcc tggtatcagc caatctcttt gtacttgatt gatcagctga tttttttcca
    71821 agtcagtcat gattggatgc agaacataga gagacttttt cttatcagta agtgtgagag
    71881 gtacagtaga aaaaataata tcgtaagaag tttcgtcaac ctcgtgtaag cggtcagctg
    71941 aattagtctc tgtaaaaaag atcatcggga ataattgctg aagttcactt tttaagatca
    72001 atgaagagct aatgccactt ggacagacga tcacggctct tatttttcta tttctttctt
    72061 ctgcgtccgc ttttctgatc tctccgccaa atagtatagt gaaaaaacca atctcttctt
    72121 cagggatgct cttccctatt cgtctttcta acggaagtaa tgcttttctt gtcatttcgt
    72181 agatggaagc atattgatgc ttaatttgat cgatcatcac attaggtaaa taaaaagaat
    72241 aggaaatacg aaaataggca gggaccaagt gataaaagac attcatcaat aattcacgaa
    72301 acgaagcaaa ttctacggcc atcaggaatt ccatgcgatg gatgacttct gaagaacatt
    72361 ccagcaaaaa atcaagtgca ggctcctgga catctccttc aacgatcgat gctaagcaaa
    72421 gagagaaaaa tataatctcc gaattttgat gttcggaata gccaaggcca gtcaatactt
    72481 gtcgactaat gtcagtgact gcaagagaag ccaacagttc agcatctttt accagttcca
    72541 tggatgtttt tccaattcga atggttgtca aactcaaata ataagctaat tcatccattc
    72601 gatttggtgc gaatcgaaga tctgatagtg aaatcgtttt atctagcaaa tctctaactt
    72661 tggcgtaata atcaatggaa agggttgcgg ttaaatacgt gagcccaaat cttccagcaa
    72721 gtgactgcat caaacgagca gtgcgatttt ttgcttctct tcttaatatt gcttctgacc
    72781 ctagcagcct aaaaccagtt ttcctagtat acgacagctg acaatcttcc acttctaatt
    72841 catttcttat ctttttgata tctgacagga ctgtcccttt agaaacctga agaaaatctt
    72901 gaaaatgaaa aacagaaaca gacgttgcag tcgaataaac catcaaataa agaagatctc
    72961 ttcgctcttg ttcggtatac acagcttcaa atcgagtaat atccaaaaat ttttctgccc
    73021 agtcgattgc tcggaatttc tttatacgga tacgggtatc atccacatat tcggcaaaag
    73081 gagttaattg tttgatcgcc tcgcttgtat ttacttcgat gatctctgct gctttttcta
    73141 gactgatttc tcttggtgtt ttcaggagat aactaatttt gtagttcaca gcgctgttca
    73201 cctcctactt atattctagt atggtagcgc ttttaaatcg aggggtgttt ggtacaactt
    73261 acagttggat tttttttacg actgtaccga acgatttcta tcgaatggat acagaaaaaa
    73321 agcaggtgac caaatgtctc ctacttttat gaattgattt cgtccgatca atgatgatca
    73381 tgtttatttt ttgaggtcag ttcttcaaat ttttctttga catcttcaac cgctttttcg
    73441 atatcttttt caaagtgatt gggctcatta ggctttgttt cctcttctac agaatttgaa
    73501 ccagataaag ctgtttcttt attttctgtt tcaccagagt ttgtgccagc taatgattct
    73561 tctttgtctt ctgtttcacc agaattagtt cctgctaaag ccacttcttc ttctgtttta
    73621 ggggccattg aacctcttaa tcgtttgtgt ttttcaccgt cataatttgt catgttggtt
    73681 cctcctagta gttctatact ttttcatcgt acaataagac agtttatgcg tcaaaaaaca
    73741 aacccgattc ttacaaatat gtcatatttt tccttctgat tcttgaatgc ttttgattcc
    73801 ttcttccaaa attttcattt gtaagattgt ttcttcatct ttgatgactt tttctgcgcc
    73861 attaactaat gtctcgtaaa tcccttcgta gacacggctg taatcaccaa cctcggaaat
    73921 tactttttct tcatgataac tcccttgttc atctatatag gtcaatacac cataatgttc
    73981 gggcaaatcg ataccaaagt cttcatgatc aggcatgtaa aacattttca gatgttcttc
    74041 ttgtcgatct tttgtttgtt tcacgaacat cccttttttt ccgtaaacga cgaaacttgg
    74101 acgttctttg atgcggaaat aactggattt tatcgaaatt ttcatatttc catagaaaaa
    74161 atccagatcg aagtaatcat tcattcgtcc tttccctaaa agttgacgta catcatagct
    74221 gatatcatct ggttcgccga aataagaaag aacttgatct actgtatgac aagcatgtcc
    74281 atataaatag ctgttcgcag tagaaaattc atgcgtattt tctggtactt ccggtctgaa
    74341 ataatcataa tgcatttcta cttctaaaat atcccctaat tttccgcttt cgattacttt
    74401 ttggactgtc aagaagtcag aatcgaaccg tctgttttgg taacattgga taaatagacc
    74461 tttttctttt gctaatgcaa ataactcttc tgcttccttt gacgtttctg caaaaggttt
    74521 ctctactagt acattcttac catgttcgag tgccattttt ccatattcat aatgaaattg
    74581 actaggtgta gtgatgacaa ctaattggat ctcaggatca tcccaaagat cagacagctg
    74641 atcagtatat tcgatgtctt cgaatgtttt ccacactggt tcagatgggg aaaaaatttt
    74701 tttgatattg attttgttcg taagttttct tgaaaaaggc aaatgatagc gatttgtact
    74761 ctttccattg ccaagataag cgattgtaag catgagtggt gcctcctttt attgatgttt
    74821 tcagtatatc ctagaaaagc gcagaaagta tttataatag ctattctggt aaaaaagttc
    74881 agaaaaacac ttgttatcat tcggtttggt gaaattaatg ttcaaagtaa ggataaaaat
    74941 caaaaagata gtagcggaac caagtgttta tcagtaagat agaatttgga ggtcagatca
    75001 tgcttattga agaaaaacta acaaaacaag agttgtttac cacgacagag aaacggattg
    75061 tcgattacat ccgtaggaat atcgaagctg cagtctacat gacgattgaa gaattagcaa
    75121 aagctacgta tacttcccat tcagctatca ttcgtttatg caaaaaaatg ggattcagcg
    75181 gatttaaaga attccgtttc gagctggggc gggaagttca tcaattgatt gctcagttca
    75241 atcaaacgat tgatcctaat tttccttttt caagtgaaga tagcactcag caaattgcaa
    75301 agaaaatggc ggatttatcg atccagtcaa taaaaaaagc acaattgcag attgaacatg
    75361 aagatttaga tcaaatcggt aaagtattga acaaggcaca gcgaatcttt ctttttgcaa
    75421 aaggtgattc tcaaatcacg gcaaggaaat tccagaataa aatggtcaag ttgaataagt
    75481 ttttgatcat ggctgaagaa tacagtgatt cttcttggaa tgcagccaat ttgactagcg
    75541 aggattgcgc catttttatt agctacagcg gtcgcatcca tcattatgaa cgaataatga
    75601 cctatttgaa gcatgtagag gcccctacct tgctgattac cggaaatcag cattcagaaa
    75661 tggccaaaca ggctgatatg tgtcttgtta tatcgcagga ggaatatgat tttgctaaag
    75721 tagcgacttt ctcctctcaa attgccttcg attacgtatt aaatacgtta ttctcagtga
    75781 tatattctca aaattttgaa gagaatatcc gcaacttgaa aaacaaacaa gaattgatgc
    75841 aaaaaggcct tcttaaagaa tatcggaaaa cttaagaaaa gatcctcatt tagtaataag
    75901 aaagatagtg tttgataggc tctctttgat atcatcataa aaacaggctg aagttttctt
    75961 tttcaaacct cagcctgttt gtttacggaa cgattcgaat agatatatta tagaaatgag
    76021 gaatagctaa cttctgtttc ttattttgaa cgattgacga aaaagatata taagaaggag
    76081 gaaaatcagt atacatgcag ctaacaatcc atacaggaaa aatcgtttgt tctcggatac
    76141 tttctgtact tctttttgaa cttcttttgc atgataagga acccggtgcc ctctgacaag
    76201 taagcgatga ctgttgacca tataaggtgt acaagttagg agtgtcacga aatcctgccc
    76261 tttttcgatt ctcagatctt ttgtatcagt cggttctacc gtcttgatct gatcgacttg
    76321 ataagcgagt gtccgtccat tgatttcgat atagaaagaa tcacctaaag tcagtttcgg
    76381 taagtctgtg aacaactttg cttgaggcag tcctcgatgg ctggaaataa cggcatgtgt
    76441 attttctccc cccgtaggat aagacgttcc ttccaataat gaggcacctt tttctagcag
    76501 cacagtattc gtttcatcaa aaattggcaa atggacattg atctcaggga tcgtcaaaat
    76561 accgatcgta tgtttctcaa aataggttct atcctttttc gcaggttctt ttttcttagt
    76621 aaagggatct gcacctggat ttccaccttc ttttgctaat tgctggtttt tctttgtcat
    76681 gttttcttgg attttagcca tgacttcttc attttctttg accgcttgtt gctgataatg
    76741 agagatgatc tgctgatcca gataattatt cagcgcgtcg ctaacaaatg gataagctag
    76801 tatccctatt cctgagagaa gcaagaaaag catcagcaga tctagaagtt tccttttctt
    76861 tggtttcatt tgtgttctcc ttgtgatgac tgtttgataa taaaagaaaa aggagcattt
    76921 gcgtaatccg ctgctccttt ttccaattct tgcaaaaaga ctaaatctga ctgtgcttgc
    76981 gtctagcaaa gtacagtcca gcaatcagta gaaggactac tcctgcaccg atatacacat
    77041 agattccctt accgcctgtt gaaggaagtg tacctttgtg tttatttggt attttttcag
    77101 gagaaatcaa ctgtcctgct gttacataag attgttcatc gatagtaaat gctacacggt
    77161 ttgttaatgg aacatatttt tctggcgctt tcgtttcttc cagatagtac gtgccatatt
    77221 ttagacctgt cacatcgatt aaaccgttac ttgtggttgt aaaaaccgtt gctgattctt
    77281 tcgccgatac ccagctgacg gcttttgtgg atgggtcgat cgataaatat ttcgctgtgt
    77341 cactatcttg atcacgaacg acgaattctg ctccagcaag tgtttggtct gatgtaacgt
    77401 caccatctac tttaacaaat cgtttgcccc cagtaacgac atcgactgac ggtggtgttt
    77461 gatcatttgt atgcccgtta tcgacatttg cttggttaga aaatcctttg gttggatctg
    77521 ctttttcgtt caaatgcata tagtaaacga atttcaatgt accgccagga gttaatgaag
    77581 gaatataatt cggatcaact gaaaccgtga atccgtctgt ttgctcagtg acagaataat
    77641 ttactgggtc gatttcttta tttccatcat ataaggcata agcatacgtt cctgaagaat
    77701 cattatcaaa tgttaaagca gcgtcatgag tatcgataag tttgaatgtt gtgtacttgt
    77761 tttgcgttcc ttctttatca gcgataccta atgggatatt gacagaaatc tcatattgaa
    77821 ttttttcacc gattgcgaca tcttttccat tcaattgagg tgttgtttta tcaactttag
    77881 acgtatcatt tttgatggtc ttttctactg gtgtttggct atttgccagg atctcaaaag
    77941 gcgtgattgt ttgcttttca atcatttccg cattatcagg agcttttact tcttctaaat
    78001 tatattttcc aacttctaaa tgattaacga tcaactggcc tttttcaata gatgcctcgg
    78061 caaagtcatt gttgccgatg tcataagaat gaccagtaat gaaatgtttg gctttggttt
    78121 gatcagttgt ccaagtgtac aatccatctg tgacactttg gatgtatttt ttgacgcttg
    78181 gtgttccttc ttctttagaa ataataaatt ctgctccatt tagtgcttcg ttttcggcag
    78241 taccgatttt tgtaactttc aacgttccat cattaccgac tgtattttta gggtagagat
    78301 ggatagtatc tagttcttct gtcccgtatt tataagagcc atctgcttgt ttgatcatct
    78361 catatacagg gaaagctaaa accatgtttg cggcagctga cactccgtct tttggttctt
    78421 ctttgatcgt gtagactgca tctttcccat tttgtttttt aggtaaagat aaagtgacat
    78481 ttccatcagc atctgtcgtt cctgaagcaa ctggtgtacc aggagtcaaa gactggactg
    78541 cttgttttgc tgcatccacg gacgctcctt tatctcgttg cgcataaaat tcttgagtga
    78601 cgttataaac tgaaaatgaa atatcggcta atccttggta ttgatcgaat tcgctcattt
    78661 ctttcccgct gttttggatt aaaggatcgg gtaaatcagt cattttcttt ttatgaagga
    78721 tgacttgagc tgctgtctcc tctgcaaaca ctttttttgc gccgaagctg tttgtgagta
    78781 atggtaaaat aaggaaaagg actcctaaca taacgtttat ttttttatga tttttcattt
    78841 tttcactcct gttctttttt tgataaacaa ccagattgca aagcttgcga ataccatacc
    78901 aacaacgcct aaaagtgtat ttttcgtttc gtttgttttt ggaagaaatg gacggctatt
    78961 ttctttttta ttgactactt tcaatatact gtccgcctct ttatcctcag aaagaaaagt
    79021 tgaaatggta aacggaattt ctgtttcact taaaatataa ccagaaggtg cttcgatctc
    79081 ttttaatcga taacttcctg ttttcaaccc ggaaattgaa aaagcgccat ttttatcgga
    79141 aatcaggtga agcgcatctg attcgttctt tgtccacttg tatccgttgg ctgtttgctg
    79201 gaggtaattt cctgctttgt ttttaataag gaatactgcg ccagctaatc gtttatctgg
    79261 tttatttgtc tcgattttga caaattgctt actccctgta tatacagaga ctttctttgt
    79321 actgacacca aaaccaaaat ccagtgttcc gttgttgttg atttccttgt tcgcctgtgc
    79381 tgtactgctt agctgcatct gataagaaat ggtcagtttt tttccagcat atttttccaa
    79441 cgaagggatc gaaaataaaa catcaaatcc gtgaggtttc ttgtgtatga caaagccttc
    79501 tgtcagcttt tctccattcg atgaaatcgt taaactatta ggtaaaaacg ttaatgcttc
    79561 atccgcacta tctgacaatt cgaacttttg atagtcaagg atatttacag gaattgtcgt
    79621 atgcaaggaa taagtgattt tttcaccaat cgtaaaatca tttctaggct cttctaatac
    79681 cttctcaaaa ggtggatcag ggtagtcgtt ttcttcattt ttaggataca aatggatagt
    79741 tgaaagtttt tgattgtttt gtccatgtac aggaagaaca actaccatat tctctgcctt
    79801 ttctttgacg acttctggta ctttggattc aatgaaaaga tacgctttat ctcttttttc
    79861 ttgatcttta gcggccagag aaaaagaagc gataccatct tcgttgttaa gagttgtagt
    79921 tgttgcttct gcggtaaaca taccggaaga cgcaccgttt tttgcgatct ctgcttgtgc
    79981 ttcttctacc gttttgccct tttcccgtag atggtaaaaa gaatctgtga catcataaac
    80041 ttggaatgtg acaccattta atcctcgata cgtttgtaat aaagcttttt cttgtccgtc
    80101 atttggatga tttttcggca gttgcccgtt tgggaaaagc aatttgtgta aagtaatctg
    80161 aaccatttct gtttctgttt ctgttgctac ctgagtaaaa gctggtttaa atagtaacaa
    80221 gaagagacac atactaagcc aaccaagttt tttcatattt agctgccccc tctttctttt
    80281 ttcaaaaaaa gataccaaat agaaaacgca caaccaatca tccctactag atagattcct
    80341 aaacggccaa ttcctcccgt ttcaggtaat ggtacttttg cctgattcgt gatgtctaaa
    80401 gaaatctggt tgtttttggc tcctggtgac agaacagatt catgatcttg tccatccact
    80461 tgaattgacc catcttcgtg tataactata gtaactggct cttttagacc ttggtatcct
    80521 tctggtgtaa aagtttcggt cagcgtataa gttccaggtt ttaaattttc gaatagaaag
    80581 gtatctgttt cttgtccatc ttttggcgat tctaagtcca tttctggtcc ctgcagtctg
    80641 aattttgctc cttttaatgt ctgtccgttg tcttcttttt tgtgtaccgt tagatcaaac
    80701 gcttttagtc gattttgatg agtgagcgtc catacattat ttgtcatctc ggtatttttt
    80761 cccgtgtaaa tgatttttcc atatttatcg atttggaatt cataatttcc cggcgaagta
    80821 tcatatccgg caggaccagc tgtttcaacg actcgatatt taccaggtgt gagtgaatca
    80881 aaactggcaa gacctttttc attcgttgtt tggctgtcaa ttggctgata agtaccattt
    80941 gcttcttttt tctgtaggga aaatgctgct cctttaagat ttatctcttt gtccgtccct
    81001 tgcatcgcat acttacgtac tgctacagga acttcaacaa aaggattttc aatagtcaac
    81061 tggatcgtat catcggaagt agtgactgtt tttccatcaa tggttaccgt accatcagaa
    81121 gcgatcttga tttcccaagt agtctttttg cttaatccat gcccttctgg agcttttgtt
    81181 tctgtcagcg tataggtcat ttctttttgc aatttgacat tttctggaag agaataggtt
    81241 ccgtcgccat gatctgttag taaagtatca atagaatctc ctgttaattt gaaaacagcg
    81301 ccaataagat ccttttcacc tgtagaggaa tttttcgtta ttttcaagtt taacggtgtg
    81361 aattgtttag tatttttcca tgtcattgca tctatttgtt gagaatcgta tcctggtaca
    81421 ggtaattctt tgattgtttg gtaactgaat gcttgacctt gattattgta ttgaggtagt
    81481 gataatatct cttgataact ttctccgcta tttgcagata atttgtcaat gtctgcacgt
    81541 tcccacgtat ttgttgtatc tttagctggt ttaatgattc gaatatatcc gtttttccaa
    81601 gctgcagcat ttgtcgtatg ttcccgttga atctcaaaag taacttgatc tggacgatca
    81661 gctagattgt tgtcaaattc ttcccataac tttttgatgt gaagactgac tccgggagct
    81721 ttagcagatg gtataccgaa ttcagctaat tcattggtat caatgtttgg ctggaaagtt
    81781 gtcctgccgt tcatttgata ccagaaattt ggatggaagt cctcattttc tgtttggatt
    81841 ctcacttggt aatggatttg gatttcttgg tcttttccta aatagatctg attgctcttg
    81901 atggtatttc cttctatgga aatagatgga gtgaccgttg taggacttgt ccccacactc
    81961 ttgactgaaa gtgtaccagg ctgataaatg aatggttctg cgattggatc atttatttgt
    82021 ccattgctta cagttgctga gatctgtaca gcttttttgg ctaggtattc agagatatct
    82081 gttgcatgat cagctgattc atagtaaaga tcgccttttt catctgatga aaccatttgt
    82141 cgcatacgag actctacttc tgcttttgag agaccagctg ccggatcgct ttgaagttgg
    82201 atgccaagac catgtatttc gattcctcgt tctttgagtg ccatcgcttc tccgatggtt
    82261 gcgataaacg tactgtcgat tcttctggat agattgtttt ggtcaggtgc atcatagatt
    82321 cttgagatta gagaagtatt tcccggccga tcttgcgtat tagaaaactg agttccgtaa
    82381 taattgctgc ttgattgtgc gtgtacccgc tgtactttat aggaaaatgt tggtacacca
    82441 tccgtcagca aaacgatcac ttttttatgt ccatttggaa cggatagcat gcttcctgca
    82501 tctcttagtg ctttttgtgt aaaagtacca ccatttgtcc gtgaaggtgt aatggatttt
    82561 acttgatttt tcactgaatc aaatgaaccc atctgtactg caccgttact gtagctatat
    82621 ccttcgcttg agtagccgac atatcccata ttgattttgt ctgtgatacc gctatctgct
    82681 aaagtatcga caaaacgatc gacaccaatc tttacttcac cgatccgatt attgtcgttc
    82741 atacttcctg accagtctac gaccaatacg agatcaagag gcgtgatatc tttttgtaca
    82801 tttccacgag cattcaaata aacatcaaac aatccgggtg tacttgtttc ctttgcatac
    82861 tttcgtatcg catagtctgc ttgattaccg gttcctccat attcgatata cgaatgggtc
    82921 cgatcattag gatctccatt ccaagaattt ataccatccc attgatttgt tccgttttta
    82981 ttgccttgat gatcaagaac atttgtattt cctgtaggtt gccaactggc tttaggataa
    83041 gtgccctgat catctgttgt atattctgta ggaatcgttt gattagatgg cacactcaca
    83101 gctggcaagg ataatgtagg caatgtaaat gggctgacag aattttcgtt ttcttttgat
    83161 gattcttctt ctatttcgtc tggctttggt actgacacat ctgtatcttt cttattttct
    83221 gtctcatcaa taatgtcata ttctttatta tcgacgatca gcttgtttgc ctggctgtgg
    83281 taaagtgctg gatcgattgg aaaactcaga tcgatagttt gtttagtgtt tgatgagatt
    83341 tccaacgtaa ttttcccgct atttacctga taagcatagc catctccttc ttttctttcc
    83401 acatcactta agtaattttc gactagacca atttcttttt ctatcttttc agcactggtg
    83461 ttattcgcat ttagcttgat gttcagtgct ttttttccag actgatccga aatgacttca
    83521 gctgaaattg tttctaaaac tgttggatca tctgtagtgt ctgctattgc agataatggc
    83581 acaaagtttg ataaactcaa tattatcagc atgaaaataa ctttcagttt cttccctgtg
    83641 gtcgtcattt ttcccctcct ttttcttttt ttctgttttg acgtgaatag tgaaaattat
    83701 taaaataaac aggcgttaca taattttatt tattttaata tgataattat tatacgaagg
    83761 gcgctaaagg gaatcacacc aattttcata ccaattggtt tcatttatga agttgattcc
    83821 ttcgattaat gagcgtttca ttgaaagaaa agggttgagg gagaaaaaca tatgatcagg
    83881 ttgttggaac gaaactatag aaagatggaa aaaatcattc gaattctgtc catttctgac
    83941 aagtggatga ctaaaaaaga acttgccaaa cgaattggta gttcagaatc tacatttgta
    84001 aggtataatc gaagagatca aaatccgctg gggaacggat gtaacgattc aatcttcaca
    84061 aaaattgggg tatcgtcttg aacatttgaa tgtaccagct tatttaaatg ttctgatgga
    84121 aatgtcgcaa agttctacaa acagtcgttt attaaatgag attattgtca atccgggtaa
    84181 aacgattgag tattattgtg aaaaaatttc catcagccgg tcttctttta cacgtaagtt
    84241 gaaacaatgc aatcaaattt tagaaagcta tttattaaaa gtgatcgttg accaaggttt
    84301 tcagttaact agccttaaaa gtgagctcca gttgcgtatc tttgttacct ttttcttttt
    84361 aagttactac ggaagacgca cgttgccatt tccaatcgaa aaaaagaaga tcaaagaaat
    84421 tatggtcaag aataattgtc agatgaattt gtttcaggaa gaaagcccat atgagcaatc
    84481 tttctttatt atgtattttg ttgtgcatct catgagagaa tcccaaggaa ctccatttga
    84541 atggaaagct ggagactctt atgtacagtt gataaatatc gataaaaaag acttcttaat
    84601 cttgaaaaat ctcttaggaa aattgaagta cagcagctat ataaaagtag tgaactattt
    84661 tgtcaatacg attttttcag aattttcgga gaaagaaaaa aatgaaatca gtgagcagat
    84721 acgaaaaaat atgtcctact gttcgttttc atccgctgat tgcaaagaaa aaaacgaaga
    84781 atatgttgtt caattattaa cgcaaattta ttttttctcc cgtattttcc catacgatac
    84841 gactcatttg acgatccgtg caacttactt tgcacagcag atgcaacacc gccagatacg
    84901 tctatatgct ggatttcgtg cagaacttca attttattcc actctactga atcagaatct
    84961 gatttattat ttatctagct atatcttttg gatgcttatc ggtaatcctg aaattcacca
    85021 ttatacttct gataaaaaaa tactgattat cagcgactta agtcttcgac atagtcaata
    85081 tattgaagaa tatatcagtg atattcttgc tgtgcataaa attcactctg agacaactgc
    85141 tattactgaa gatcagctgt cgaaatacaa tcttctcgag tatgatctga tcgttacgaa
    85201 tcaacccatt ttgaatgccc atgttcctca tatattgatt gatgatagtg tgtcattcgc
    85261 aaatgaagaa gaactcatcc gcttattcga gttatgaata atcaaaaaac agctatgtat
    85321 aaaccaccct gataaaaatt tcaggacaaa tacacatagc tgtttctttt tattgtattc
    85381 cttcagcaat ccaacgagat ttatagcgaa agtcttttaa caactcttct tttgtccaat
    85441 tatttgcaat gagatccgtc aaagtgttca ttacgagggt catggaaaag tataggaaac
    85501 taactgcttc ttccgacgat tgaatggaga aatgattgat tcttaataat tccagccatt
    85561 tttcgttcat tggagaatca gccgatagtt ctctacgttt ggttgtctgc tgatcatttc
    85621 gctgggttaa caagtataac ctttgccaat agatactttc gtgatctaag tcgcagcacc
    85681 actctaaata tttttcgatc cccaaaaaga aatgttgttt gttttcgcta atgaatttta
    85741 agatatcttg atggactatg tgagaactgc ttttgatcgt atacaaataa gcatcttcca
    85801 aatcttgaaa atatttataa aaagcaccgc gcgacatccc catcttgtca acgatttctg
    85861 agactttgac ttggctgatg tgctgtgagc aaaatatctc cagtaatagg tcatcgattc
    85921 tctgtttctt tgcgttcgat aaattgaaaa aagtttcttt tggcatccac atctctcctt
    85981 tatctctgat tatacgtgga tagcccttca ttgtcatgaa ggattcattc cttctttttc
    86041 tcttcttctg tcaagtaccc atcttccatt cgataaacgc gatcactcca ttgaatcata
    86101 cggacatcat gagtaaccat aatagtcgct ttttgtttct catgagcttc tttaactagt
    86161 aatttgacga cttcatatgc atgatctgta tccaaactag ctgttggttc gtctgctaag
    86221 atcaagcttg gctcattata taaagcgcga gcaattgcca ctctctgtct ttctccacca
    86281 gaaaggtctt taggataact atttttaagt gactggatat ctaaagattg cagcaaggaa
    86341 tcgatttttg ttgaatcttc tttttttgaa gtaacttggt caactagttc aaattgttcc
    86401 tttaccgtta aaaaaggaat caaattagag ctttggagaa taaatcctat ttctttaaag
    86461 cgtaaatctg ctcgtttttt ttctggaagc tcagttagtg agtgaccgtt gatcactatt
    86521 tctccggaag tcggtgtttg caatcctcct gaaatggtaa ggaaagtact tttacctgaa
    86581 ccagaaggac caatgatgct gacgaattct ccttccttta cataaaaatc aattgctttc
    86641 aaagctgaga cctttgtatg accagaacca aatgttttgg taactttttt catcgttaat
    86701 atttttttca tttttattaa cctcctattg ctgtaattgg gtctactttg gttatcgtac
    86761 gtatcgaaaa caatccgcct agcattgcga caatgatcaa aatcccacta tatagcaacc
    86821 attgtgacca aaaaacagca aaaggcatcg cgcttggtaa aatcagacta gtcaaataag
    86881 caaacaaaag agcaagcaga acgcctacca ccccaacaat aaaggactgt gctactaaag
    86941 atttagcgat gaagaaattt ttgatccctt gtgctttcat tactccaaaa atagcagtct
    87001 tctgaagtgt catcacgtac atgaaaatac cgaccacggc agcaaccact aagaacaaaa
    87061 agtatatcat cgcatttaag gtcatatttt gggcagaata gccaggaata ctttcaatga
    87121 atgtcccaat agttaataac tgtagaccct tcgatgcttt ttctttcgaa attttagctg
    87181 aatcctttat tacgatccca ttgatcggct gttcttcttc agaagcaaac ggctgttgtc
    87241 catacttcaa agcagtccac gtatctaggg acgcatagat gacgggagaa actgtgtaat
    87301 aagtttcagg aaagataccg acaatcgtca aaggatcgtc gtaactgcca attttgatcg
    87361 tatctccaat tttatagcct gaatcagcca gattttgaga gatgatgatt tcattctttg
    87421 ttttaaattc atgccctttc gtgagttttg gtaataaaaa tgcttctttc gttgtgccga
    87481 aaactgtaac attttctttg ttttttcctt tgattgctcc gctgtacaat ccgattggtg
    87541 ctttctctcc tccttcaatg tatttcagat ctcctcttgt taattgtgaa gctgcaaata
    87601 cttgatttgc atcctccgac aaaacaatct cttgtgcgtc ccaatcatcg attgcttttt
    87661 taaactcttc tgaaagtcca ttcgctagtc ctgacaacat gaatacgaca tacgcaatca
    87721 agaacataat accgacgatc aagccatatc gtaatttaga atagcgaatt tctttgatag
    87781 ctagaaacat ttgtttttcc tccctatgat agattgatag tgacaaaatg tcacttgttg
    87841 aatagtgtaa ctctaaagtg acaatttgtc acttgtgttg tttttttctt atcaataaat
    87901 tgtctaagac atctttcgat aaaaccttaa catgagtcat aaaaaattta tttaagcctt
    87961 atttatgctt tccatgataa actaaagtga ccaaatcaat gaggtgggaa aatgattaaa
    88021 ctattagtag tagaagacga taaagtatta tccaataata taaaagaaat actcgctgca
    88081 atcggcgaga taacacaagt ttatgatggt agtgaaggac tgttcgagtt ggaaagtgga
    88141 gtttatgatc ttgcaatctt ggatttgatg atgccggaaa tgaatggata tgaagtgtta
    88201 gcaaaaatac ggaaagaaaa aatacagact ccagtattga ttttgactgc aaaagatagt
    88261 ttggaagata agattgaagg atttgaacga ggtgcagatg attatctaac aaaacctttc
    88321 tatcgagaag aactgatcat gcgcgtgaaa gcattattga aacgctcgct aggtctcttt
    88381 gatgaaaatg ttctgaagta taaggatatc agttgtgatt taaaaagcaa tgaagtcttg
    88441 tataaagaac aagttttgcc catacaagga aaagagtttg aattgctcgt ttatttttta
    88501 caaaataagg gaatcatttt gacaaaagag cagatatttg accggatctg gggatttgat
    88561 tctgatacga cgattacagt tattgaagtt tatatgagca acttacgaaa acatctgcga
    88621 agtactggat tggataaaga aatcaaaacc ttacgtaatg tcggttatat actgcaaagg
    88681 gtgtgatgca atgaatggag atattacacg aaagcaacgt agtcgctttt ttgcgacaaa
    88741 tgtagcagca tttgctttta tcttttttct tttgggattc attactttac agatattaaa
    88801 ccaatctgca tacagagaaa cagatctgtc attagagaaa ataaattttg attctcgaac
    88861 agtacaatta gagatacaaa gatatcagca aggcgatccc tttttaaacc cgactcaaac
    88921 ggaacaaaac agaacaaaca tggaacagcc attaatggaa ccatcaaatg accgttttaa
    88981 cactcaagtg atcttgtggt ctaaaaatgg tgagatattg aataaagcag ctattggtgg
    89041 gcgtttcaac caaatcaaag aattaaaaat ggatacgaaa aatctgaata ccatccaaaa
    89101 tattgaatta aatgaagaca gtggctcatc tgccctctct ttccgttcga ttacgaaaaa
    89161 agcggagacg aatcaagatg gcgttgccta catccaaatt ttagaaaata caaatcaaat
    89221 caagaattca ttagcgactt ttcgcacgat tatgattttg tgtatgattg ttttttggat
    89281 tctctctatt ggtatcagtt attacttgtc tagtctaagc atgcgcccta ttattctttc
    89341 ttggagaaga caaaaagaat ttgttgagaa tgcttctcat gaattgcgca caccgttaac
    89401 gattattcaa aatagtttgg aacatctttt taccaagcct aatcatacta ttattgaaga
    89461 atccgaaagc atcgctcaag cattgtcaga gacgaggcgc ctcactggat tgacttcgga
    89521 tttgctgaca atcgctcgga atgattctga tcagcagctg ctttcaaagc aaatgatcaa
    89581 tacacaagaa tatatcgaac aacttgttaa accatttcaa gagatggcca tcatagatgg
    89641 aaaagagttt attctccata acgatgcaac attagaagta ccaattgatg aaaaaaaaat
    89701 ccatcaagtt ttggttattt tgctggataa tgcattaaaa tatacgaatc cagaagataa
    89761 gatcattttg gattcatctg ttaaccataa agaatggctg attcacgtaa agaatactgg
    89821 cccttctatc agtgaagaag atcaagcaag gatttttgat cgattttatc gggaagatca
    89881 atctcgggcg aaagagactg gcggatacgg gcttggcttg gcaattgcaa aacaggtaat
    89941 cgaacagcat catggacaga tttctgtatc caattatctt ccacaaggag tcgattttaa
    90001 agtccaattg ccgttgaagc ctaaaaaata atgcttatcc ctaaaaaagg gctgtgacaa
    90061 aaatcttgtc acagcccttt tttgttgcga ataaacggtg ttccagaagt agcttcttcg
    90121 gaaataagcc gaaatttctt taagctgacc acttctgtca caacctcttt agcttacgct
    90181 tacgattttt tattgcggtc ttcaatgtgt acatcaccgc ttgtgtcaat atccaattct
    90241 tctcggctaa catcttctgt cactttttca acatcttcat gttcttcttt atgaatccca
    90301 acttcttcac gaataactgt atgtttgctt acatctactt gctcttcttt gattgggata
    90361 gtaatcgtgt catcttccaa tttttcgtct gttccctgtg aagattgatc tgttactggt
    90421 ttgcgttcga tgacgatttc ttcacgtttg accggtactt ctaccgtttc agtatcgttg
    90481 accacatgtt tgtggatgtc gacttctcca gttgtcacat catgtgtatt tacatctaat
    90541 ttttcttctt ttagttgaat tgtatcatca tctagatttg gtttgcgatc gatgtcttca
    90601 gtcttgcttg tacccattgt atcagtctcg ccaggtacgt ccatcggatc agttcctggt
    90661 gtcatattca atggatccgt tgtattttga aagcctgtcg tgccacctac gtccattgga
    90721 tctgttccag tgccagtttc taatccagtc cccattgtgc ttgctgggct aacagtatct
    90781 tgtgtatcca ttgtatcttc tgttgtttct ggctgacgat agccttttac tgtgatgaca
    90841 aattttccat cagaaatatc tcctctatat tgatataaag gatcattttc tggtgtagcc
    90901 gtctcagaat cataggtatc aaaagaaaaa gtatctttta ttttttccca taaagaacgg
    90961 tcttcttcac catccatccg attttcatct gtttcaacat ctataccaga caatccgtca
    91021 aatcctagtc tagatgctgc ttcatcagta gtataaataa cgatatcatc tcgttcatac
    91081 ccttcgttac gcaaccgttc aattactgat aatgcttctt ccctcgtact atagcttccg
    91141 atgaccgtta aatttttctc ttccatgtaa attcctccta gcaaatagat ttatgattgg
    91201 tatattgtta cttataaatt tattctatag gagacgattg ttttctacaa atatttagat
    91261 tggaatttga ttaaaacaat ttaattgaaa tttgaaaaca tttatgttaa tgaaagtcat
    91321 attctaataa aatgtcattt gtttctatat gaatttttat gaaaaatttc atataatttc
    91381 cactcgttgt gatggtttaa tttatccaat ccatcaataa gcaaacaact tatataaaaa
    91441 aggattaatt ctcaatataa ttgctcctac catagaataa atcttcatgt aaagtaatga
    91501 agtaccaact atttctaata cttctttaag aattatccca acaatatcgt tagacaaacc
    91561 attattgaat aaatggagag ccaatcgatt ctgaaaaaat gttttctaat ttttcggaaa
    91621 taaaagaaag agcctcctgc cattagaacg aaccaaatcc atttcattgc tcatgaagta
    91681 accacatagc taaaaagagg ataaatcaat taaaagatca aaagaatgac tgcactaata
    91741 aaataactaa aaatgtatct tcttacttca tatcttttag ctagtactta gttaaaaatt
    91801 tgcttcctaa gatcaagaca aactgtctat cttcatttga tgaaatgcgg taaaatatag
    91861 aaaatgaaca ctattggagg gaatttgtaa tggacagcaa aactagaaaa caactgcaag
    91921 aaaagttaaa gcaacgtaca cacttgctcc cttccgtctt tcaacagttt ttagaagaaa
    91981 atcgttcttc cctttcatta ggcagtcgct atgaatacgc aaaagatttt catctgttta
    92041 ctgattattt gagaaaagta ttttctgaag aagtggatga tcagctgatt atccatttag
    92101 aaaaacaaga ttatcagaat ttcttagcta aaatctatcg acatactcgt tcgttccaaa
    92161 ctacagcgaa ccaagaaacg gagcaattgt ttgaaaatag ctattacggg atttcaagga
    92221 agcaatattc attaaatcat tttttacgat ttttgtatca aaaaggactg attgaagaag
    92281 agatttctct tttgggtaca agtttaccgg aaacaaccaa agcagctccg cgatatatcg
    92341 atgcagaact tttcaaagat tttgagcatt tgtttatccc gattgaaggc tttcaaacaa
    92401 gcagagaagc tagctttgaa gaaaagaata gaccgaggaa ccttgcaatt actgccattc
    92461 ttctgtattg cggattaaag atccatgaag tagtagaact taaacgtaaa gatgtatctt
    92521 tgaccaagca gattcttaat ctgaatagaa aagaaaacag actgaataaa gtaccaatac
    92581 caaaagaagc gatgccattt ctggagaact attttaagtt aacagcacaa aatacggacg
    92641 aaaattcttt tgtttttcgt tcctcacatg atcagcaaat ttctcctcgg actattcgcc
    92701 aaattttgag caaaattaca gtatataaaa acgtatcgcc agaactatgc agaaaaacat
    92761 atcgttatta tgcagaacta tatttagatg atgctgacgc ggtaaattat ttatgtggta
    92821 atcgatacct ctcatcccat tcttttcaag atatctggga aaagatggtt gatttttctt
    92881 atcacgaatt agcggcattc gttcgggttt cttccatata aaacaaatgt atgatctttt
    92941 tttcacaata aactatgtta ttatataaag gattatgtta cgattatctt gaatttgtat
    93001 attacttaac aaaagataat ggagtgtgaa tgatggagac cataacgtat tcccctttga
    93061 acttatttac gaattttcaa gaagctgcag ctaacttttc cgagaccccg attatctttg
    93121 atgagccact ttcagctttc ccagaattag gacttgaaac aacttacaaa aaatgctgcg
    93181 aaagtgtgtt gaaacgggct tatcaattgg ctcatcttgg agtgaaatcc ggagacaaag
    93241 ttattattta taagagttcc gcttttgaca cataccttct agctgtttct gtgtcttacc
    93301 ttggtgcagt gcctgtcatg acttcttatc atctaccaac aacaacaatg gaagtattta
    93361 tcgatcgttt agaagaccct ttcattttat ttgatgatga gacaaaaaag cgagtgagag
    93421 aaatttcaaa tggaacaaaa tcaaaacaga ttcc
//
LOCUS       DARPZJ010000004        90308 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.004, whole genome shotgun sequence.
ACCESSION   DARPZJ010000004 DARPZJ010000000
VERSION     DARPZJ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 90308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.004"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            9..587
                     /locus_tag="SLE23_000345"
     CDS             9..587
                     /locus_tag="SLE23_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467280.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(827..910)
                     /locus_tag="SLE23_000346"
     tRNA            complement(827..910)
                     /locus_tag="SLE23_000346"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(874..876),aa:Leu,seq:gag)
     gene            965..1144
                     /locus_tag="SLE23_000347"
     CDS             965..1144
                     /locus_tag="SLE23_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467281.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            1293..2510
                     /locus_tag="SLE23_000348"
     CDS             1293..2510
                     /locus_tag="SLE23_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8467282.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2694..3530
                     /locus_tag="SLE23_000349"
     CDS             2694..3530
                     /locus_tag="SLE23_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467283.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3606..4754
                     /gene="nagA"
                     /locus_tag="SLE23_000350"
     CDS             3606..4754
                     /gene="nagA"
                     /locus_tag="SLE23_000350"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEI8467284.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4975..6033
                     /locus_tag="SLE23_000351"
     CDS             4975..6033
                     /locus_tag="SLE23_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HEI8467285.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6037..7071
                     /locus_tag="SLE23_000352"
     CDS             6037..7071
                     /locus_tag="SLE23_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HEI8467286.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(7173..7889)
                     /locus_tag="SLE23_000353"
     CDS             complement(7173..7889)
                     /locus_tag="SLE23_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEI8467287.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7858..8643)
                     /locus_tag="SLE23_000354"
     CDS             complement(7858..8643)
                     /locus_tag="SLE23_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HEI8467288.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8634..9383)
                     /locus_tag="SLE23_000355"
     CDS             complement(8634..9383)
                     /locus_tag="SLE23_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEI8467289.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9681..10205
                     /locus_tag="SLE23_000356"
     CDS             9681..10205
                     /locus_tag="SLE23_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HEI8467290.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10221..11720
                     /locus_tag="SLE23_000357"
     CDS             10221..11720
                     /locus_tag="SLE23_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HEI8467291.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11808..12410)
                     /locus_tag="SLE23_000358"
     CDS             complement(11808..12410)
                     /locus_tag="SLE23_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8467292.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12514..13470
                     /locus_tag="SLE23_000359"
     CDS             12514..13470
                     /locus_tag="SLE23_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEI8467293.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13775..14731)
                     /locus_tag="SLE23_000360"
     CDS             complement(13775..14731)
                     /locus_tag="SLE23_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8467294.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14905..15465
                     /locus_tag="SLE23_000361"
     CDS             14905..15465
                     /locus_tag="SLE23_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467295.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15458..16282
                     /locus_tag="SLE23_000362"
     CDS             15458..16282
                     /locus_tag="SLE23_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEI8467296.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16292..16909
                     /locus_tag="SLE23_000363"
     CDS             16292..16909
                     /locus_tag="SLE23_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEI8467297.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16927..17610
                     /locus_tag="SLE23_000364"
     CDS             16927..17610
                     /locus_tag="SLE23_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEI8467298.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18293..19576
                     /locus_tag="SLE23_000365"
     CDS             18293..19576
                     /locus_tag="SLE23_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8467299.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19592..20479
                     /locus_tag="SLE23_000366"
     CDS             19592..20479
                     /locus_tag="SLE23_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8467300.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20496..21332
                     /locus_tag="SLE23_000367"
     CDS             20496..21332
                     /locus_tag="SLE23_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8467301.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21335..21958
                     /locus_tag="SLE23_000368"
     CDS             21335..21958
                     /locus_tag="SLE23_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467302.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21955..23247
                     /locus_tag="SLE23_000369"
     CDS             21955..23247
                     /locus_tag="SLE23_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8467303.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23606..23703
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23819..24400
                     /locus_tag="SLE23_000370"
     CDS             23819..24400
                     /locus_tag="SLE23_000370"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEI8467304.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24403..25710
                     /locus_tag="SLE23_000371"
     CDS             24403..25710
                     /locus_tag="SLE23_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEI8467305.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26126..26614
                     /gene="purE"
                     /locus_tag="SLE23_000372"
     CDS             26126..26614
                     /gene="purE"
                     /locus_tag="SLE23_000372"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEI8467306.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26607..27731
                     /gene="purK"
                     /locus_tag="SLE23_000373"
     CDS             26607..27731
                     /gene="purK"
                     /locus_tag="SLE23_000373"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEI8467307.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27744..29039
                     /gene="purB"
                     /locus_tag="SLE23_000374"
     CDS             27744..29039
                     /gene="purB"
                     /locus_tag="SLE23_000374"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEI8467308.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29219..29596)
                     /locus_tag="SLE23_000375"
     CDS             complement(29219..29596)
                     /locus_tag="SLE23_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467309.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29852..30580
                     /locus_tag="SLE23_000376"
     CDS             29852..30580
                     /locus_tag="SLE23_000376"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEI8467310.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30580..30834
                     /gene="purS"
                     /locus_tag="SLE23_000377"
     CDS             30580..30834
                     /gene="purS"
                     /locus_tag="SLE23_000377"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HEI8467311.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30836..31507
                     /gene="purQ"
                     /locus_tag="SLE23_000378"
     CDS             30836..31507
                     /gene="purQ"
                     /locus_tag="SLE23_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HEI8467312.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31508..33730
                     /gene="purL"
                     /locus_tag="SLE23_000379"
     CDS             31508..33730
                     /gene="purL"
                     /locus_tag="SLE23_000379"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HEI8467313.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33715..35154
                     /locus_tag="SLE23_000380"
     CDS             33715..35154
                     /locus_tag="SLE23_000380"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEI8467314.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35177..36229
                     /locus_tag="SLE23_000381"
     CDS             35177..36229
                     /locus_tag="SLE23_000381"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEI8467315.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36226..36804
                     /gene="purN"
                     /locus_tag="SLE23_000382"
     CDS             36226..36804
                     /gene="purN"
                     /locus_tag="SLE23_000382"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEI8467316.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36801..38336
                     /gene="purH"
                     /locus_tag="SLE23_000383"
     CDS             36801..38336
                     /gene="purH"
                     /locus_tag="SLE23_000383"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEI8467317.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38352..39626
                     /gene="purD"
                     /locus_tag="SLE23_000384"
     CDS             38352..39626
                     /gene="purD"
                     /locus_tag="SLE23_000384"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEI8467318.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39748..40662
                     /locus_tag="SLE23_000385"
     CDS             39748..40662
                     /locus_tag="SLE23_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8467319.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40795..42360)
                     /locus_tag="SLE23_000386"
     CDS             complement(40795..42360)
                     /locus_tag="SLE23_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEI8467320.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42353..43804)
                     /locus_tag="SLE23_000387"
     CDS             complement(42353..43804)
                     /locus_tag="SLE23_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8467321.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43818..44834)
                     /locus_tag="SLE23_000388"
     CDS             complement(43818..44834)
                     /locus_tag="SLE23_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8467322.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45054..46142
                     /locus_tag="SLE23_000389"
     CDS             45054..46142
                     /locus_tag="SLE23_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEI8467323.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46196..47722
                     /locus_tag="SLE23_000390"
     CDS             46196..47722
                     /locus_tag="SLE23_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEI8467324.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47724..48929
                     /locus_tag="SLE23_000391"
     CDS             47724..48929
                     /locus_tag="SLE23_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8467325.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49186..50163
                     /gene="guaC"
                     /locus_tag="SLE23_000392"
     CDS             49186..50163
                     /gene="guaC"
                     /locus_tag="SLE23_000392"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEI8467326.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50427..51851
                     /locus_tag="SLE23_000393"
     CDS             50427..51851
                     /locus_tag="SLE23_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEI8467327.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52312..53421
                     /gene="pdhA"
                     /locus_tag="SLE23_000394"
     CDS             52312..53421
                     /gene="pdhA"
                     /locus_tag="SLE23_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HEI8467328.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53424..54401
                     /locus_tag="SLE23_000395"
     CDS             53424..54401
                     /locus_tag="SLE23_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEI8467329.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54426..56069
                     /locus_tag="SLE23_000396"
     CDS             54426..56069
                     /locus_tag="SLE23_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HEI8467330.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56077..57483
                     /gene="lpdA"
                     /locus_tag="SLE23_000397"
     CDS             56077..57483
                     /gene="lpdA"
                     /locus_tag="SLE23_000397"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEI8467331.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57645..57920
                     /locus_tag="SLE23_000398"
     CDS             57645..57920
                     /locus_tag="SLE23_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEI8467332.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57926..58693
                     /locus_tag="SLE23_000399"
     CDS             57926..58693
                     /locus_tag="SLE23_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEI8467333.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58861..60690
                     /gene="typA"
                     /locus_tag="SLE23_000400"
     CDS             58861..60690
                     /gene="typA"
                     /locus_tag="SLE23_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEI8467334.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            60951..62723
                     /gene="recQ"
                     /locus_tag="SLE23_000401"
     CDS             60951..62723
                     /gene="recQ"
                     /locus_tag="SLE23_000401"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HEI8467335.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGRNKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            62837..63139
                     /locus_tag="SLE23_000402"
     CDS             62837..63139
                     /locus_tag="SLE23_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HEI8467336.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63142..64305
                     /locus_tag="SLE23_000403"
     CDS             63142..64305
                     /locus_tag="SLE23_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEI8467337.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64331..67759
                     /locus_tag="SLE23_000404"
     CDS             64331..67759
                     /locus_tag="SLE23_000404"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HEI8467338.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            67780..68904
                     /locus_tag="SLE23_000405"
     CDS             67780..68904
                     /locus_tag="SLE23_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467339.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            68894..69331
                     /locus_tag="SLE23_000406"
     CDS             68894..69331
                     /locus_tag="SLE23_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEI8467340.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69315..69653
                     /locus_tag="SLE23_000407"
     CDS             69315..69653
                     /locus_tag="SLE23_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEI8467341.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            69772..70332
                     /gene="rsmD"
                     /locus_tag="SLE23_000408"
     CDS             69772..70332
                     /gene="rsmD"
                     /locus_tag="SLE23_000408"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEI8467342.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70329..70820
                     /gene="coaD"
                     /locus_tag="SLE23_000409"
     CDS             70329..70820
                     /gene="coaD"
                     /locus_tag="SLE23_000409"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEI8467343.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            70810..71853
                     /locus_tag="SLE23_000410"
     CDS             70810..71853
                     /locus_tag="SLE23_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEI8467344.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72012..72740
                     /locus_tag="SLE23_000411"
     CDS             72012..72740
                     /locus_tag="SLE23_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEI8467345.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            72856..73101
                     /locus_tag="SLE23_000412"
     CDS             72856..73101
                     /locus_tag="SLE23_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEI8467346.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73098..73316
                     /locus_tag="SLE23_000413"
     CDS             73098..73316
                     /locus_tag="SLE23_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEI8467347.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73452..73991
                     /locus_tag="SLE23_000414"
     CDS             73452..73991
                     /locus_tag="SLE23_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HEI8467348.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            73984..76257
                     /locus_tag="SLE23_000415"
     CDS             73984..76257
                     /locus_tag="SLE23_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEI8467349.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            76295..77341
                     /gene="holA"
                     /locus_tag="SLE23_000416"
     CDS             76295..77341
                     /gene="holA"
                     /locus_tag="SLE23_000416"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEI8467350.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77430..77684)
                     /locus_tag="SLE23_000417"
     CDS             complement(77430..77684)
                     /locus_tag="SLE23_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEI8467351.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78084..78353)
                     /locus_tag="SLE23_000418"
     CDS             complement(78084..78353)
                     /locus_tag="SLE23_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467352.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(78823..79278)
                     /locus_tag="SLE23_000419"
     CDS             complement(78823..79278)
                     /locus_tag="SLE23_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HEI8467353.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(79416..81344)
                     /locus_tag="SLE23_000420"
     CDS             complement(79416..81344)
                     /locus_tag="SLE23_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEI8467354.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(81541..82374)
                     /locus_tag="SLE23_000421"
     CDS             complement(81541..82374)
                     /locus_tag="SLE23_000421"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEI8467355.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(82566..83270)
                     /locus_tag="SLE23_000422"
     CDS             complement(82566..83270)
                     /locus_tag="SLE23_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8467356.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(83293..83919)
                     /locus_tag="SLE23_000423"
     CDS             complement(83293..83919)
                     /locus_tag="SLE23_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEI8467357.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            84245..86620
                     /locus_tag="SLE23_000424"
     CDS             84245..86620
                     /locus_tag="SLE23_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HEI8467358.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(86644..87135)
                     /locus_tag="SLE23_000425"
     CDS             complement(86644..87135)
                     /locus_tag="SLE23_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HEI8467359.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            87322..88242
                     /locus_tag="SLE23_000426"
     CDS             87322..88242
                     /locus_tag="SLE23_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8467360.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            88396..88740
                     /locus_tag="SLE23_000427"
     CDS             88396..88740
                     /locus_tag="SLE23_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEI8467361.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(88930..89430)
                     /locus_tag="SLE23_000428"
     CDS             complement(88930..89430)
                     /locus_tag="SLE23_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467362.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            89958..90041
                     /locus_tag="SLE23_000429"
     tRNA            89958..90041
                     /locus_tag="SLE23_000429"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:89992..89994,aa:Leu,seq:cag)
BASE COUNT        29333 a        15562 c        19328 g        26085 t
ORIGIN      
        1 ttttagacat gaatatctta tttttattgc tatttttctt aattttcctt ctaacatata
       61 ggaaatgtca aaactattat gtgcgtatat tgactgcatt accgtttttc ttaaacctga
      121 ttatttattt tggtaataca atgggtcaaa gctttactta cgtcaatgga aataaaaggg
      181 caatgatttg gagtagtagt aacctgaata atctctttac agagttagga acgaaactgt
      241 cactttttta tccaggtact tggatagcta ctttagtagt cttggcatta ttactatgtt
      301 taattgttgg aatttattta agttttgaca ataagaaaac ttctattttt ttagttattt
      361 tgatgataat gggattttgt tcaaggttaa ttatgggatt ttctcccaca gtatgggctt
      421 ccggaatgcg gacgtactat atactttatg ttgttatcgc catcttagta ctaatggcag
      481 ttaaagagct aatgaaaagc atgagtgtac aaaaaaatga atttatgcaa tttggattaa
      541 ccgtgcttgg tatttgtacc tttataataa cggtgataaa cagataatat acaaaaaatc
      601 cctcgcttta gtattaggtg agggatttta ctcgtttttc gattaattgt tttaacactt
      661 gcaagtttct acgagtagct tgtttccgac cttcatatac tcacctcagg ctgtttacat
      721 gattgtacgt tctttttgta aaggatacag tgatatgtat ataatggcat aaagaaacgt
      781 tcaaacaaaa aaactcgtga agcaaaatta acttcacgag ttgtagtgca gatgatggga
      841 ctcgaaccca cacgagctaa cgctcacatg accctcaatc atgcttgtct gccaattcca
      901 acacatctgc gtaataataa cacactaatg atagcgaggt tttacatagt tgtcaagctc
      961 aaaaatggga ggacttatta agatggagaa atatgacgga gaattttcag gactgggaat
     1021 gatcttaggt gtattgattg gacttgcatt cggacgtttt ttgcttggtt ttatgctagg
     1081 aatcatttgt ggaatcgcaa tggattgggc agcgaatcta tggaatgact atcatgacaa
     1141 ttaagttctc aacgcttgtt tgtgtttttt taatacttac gtttttccta aataagtggc
     1201 aaaattttct aggatggagt atgatattga aatagtaaat aacaaaaaat ttggaaagtt
     1261 ctaacttttt gaaatgaggg attggctaag tgatgagaga atttgaaaaa tccaacaaat
     1321 tagaaggtgt cagttacgat gttcgcggtc ccgttctaga agaagcggag cggatgcaag
     1381 aagagggcat tagtatttta aaattgaaca cgggaaatcc cgcacctttt ggatttgaag
     1441 caccaaacga agtcattcgt gatttgatca tgaatgcccg tgactcagaa ggctactcag
     1501 attccaaggg gatcttttct gctagaaaag caattgagca atattgccaa ctgaaacatt
     1561 ttccgaatgt gacgatcaat gatatctaca ccggcaacgg agtgagcgaa ttgatcacga
     1621 tgtgtatgca ggggttgctg gacaatggag atgaagtact ggttccaatg ccggactatc
     1681 cgttgtggac ggcttctatt gcattagctg gaggcacacc tgttcattat atttgcgatg
     1741 aagaggcaga atggtatcct gatattgatg atatcaaatc aaaaataacg agtcggacaa
     1801 aagctattgt tatcattaat cctaataatc ctactggggc actttatcca aaagaattat
     1861 tagaagaaat cgttgaagta gctcgacaaa ataacctgat tatttattcc gacgaaatct
     1921 atgatcgctt agtgatggat ggtctagaac atattccgat tgctacatta gcgcctgatt
     1981 tgttcgttgt tacgctgaac ggtctatcca aatctcatcg tgtagcagga tttcgagtag
     2041 gctggatggt cctaagtgga gataagtcac acgtcaaagg ctatatagaa gggctgaata
     2101 tgttgtcctc catgcgtttg tgttccaatg tattgtctca gcaaattatc caaaccgcgc
     2161 taggcggtta tcaaagtgtc gatgagctgc tcctgccagg cggaaggatc tatgaacaaa
     2221 gagaatatat ctataatgca atcaatgata ttcctggtct ttcagccgta aaaccaaaag
     2281 ctgcttttta tatattccca aaaattgata caaagcgatt caatattttg gatgatgaaa
     2341 aattcgtttt ggacttttta catgaacatc atattctact tgtacatggt ggtggattta
     2401 attggaacca gccagatcat tttcgaatcg tttatcttcc taaaatggat gatttgaaac
     2461 aaacagctaa gaaaatgaga gaattcctag caacctatcg ccaaaaatga ttttaaaaac
     2521 caaatttttc agtaggaggg ccacagacaa acacactgag gctctctttc tagtggagtt
     2581 ttcttaaata actaaagtat attatttagt tgcaagtctt ttcttgaagt ttgcgacttc
     2641 ctaaagtaaa atacgaatag aatgcgaata cgcatatttt ggggaggata cttatggaaa
     2701 cgttaatcga gtcctttgga acgatcatta aagagattcg aaaagaacaa aaaatgacgc
     2761 aaaaaatgct ttcgcatgat atttgttcac aaagtgtatt aagtcggatc gaaaataatg
     2821 aggaactgcc gaatgtattg gtgatgatgc agatttgtca acggctaggg gtaacgattg
     2881 atcatgtgat gaatctctct cgaaaaacta ctcggacaaa cgataaatta tttgaactgt
     2941 tggatagttg tttccaaaaa cgtgattatc ggaagttaga acaagtacta aaatcttctg
     3001 atatttctga aaatctgtat caagcaactg actttcaacg ctattattat tatctcggtg
     3061 tttgcgaatt cacgttgcgt caaaatatct ctcagtccct ttattatttg aaagaagcat
     3121 taagctactc tagccaaaaa gaaagaatcc atgtttctga cacagaaata caactgatta
     3181 gttgtatcgg aaaaatatat ggtgtggcag gaaaaacggc tgaagcacgc tactatttga
     3241 gtcgaagcat ccaactgctg catcaatcag ctgatgaacg atcaaaaagt gaattttcgc
     3301 aaatttttta taattatgga aatttcttat tccatcaaaa tgaaatcgac gaagcgttag
     3361 aacaggtgaa tcaaggaatc tattgggctc aagagaagaa tagctactat tacctcaatg
     3421 atttatttgt gcttaaaagc ttaatataca agcgtaaaga agaaccagaa agagcagcat
     3481 tctatgaagg cttagcacaa gctgtgaaac aaatttcaaa aaatttgtaa atggtgtaga
     3541 ccattcttga cttcttctct aaataagagt actttagagg tagaaaaaca aagggagaga
     3601 atagaatgag aacttttatc tatgctgaca aattcttttt agcgtcaggt gtcaaacatg
     3661 caggctatct tgaaattacc gatggacttt ttggtgaata caccaaagaa ctacctgagg
     3721 gagaagtcaa catcattgac caaagcggca aatggattgc tcctggtttg gtagatacac
     3781 atattcacgg ctatatgaat catgatgtaa tggataatga tgcagaaggc atcaaagtga
     3841 tgtctgaagg tctgttatct tgtggagtga cttcattttt accaacaaca ttgacgtcaa
     3901 gcaaagaacg tttaaaagat gtagctgaga caatcggcaa aatgtatcag gaagcaccag
     3961 gagctaaaat caaaggaatc tattttgaag gtcctttctt cacagaagaa cacaaagggg
     4021 cacaaaaccc aagttatttc ggggatcctg atttggatac tttccatgaa tggcaagaag
     4081 cttcaggtgg tttaatcaaa aaaattgctt tagcaccgga acgtcaaggt gtagaagagt
     4141 ttgtcaaaca agtgactgaa gaaggagtag ttgtttctct aggacacagt aatgctacac
     4201 tagaagaagc gcaaaaagct gttgaagcag gcgcaagtgt atttgtccat gctttcaatg
     4261 gtatgcgtgg attgaatcat cgcgaaccag gtatggtggg tgcgttatta tctttagaac
     4321 atgtcttttc tgaattgatt tgtgatggcc atcatgtaca tccaaatgct gcgggaatcc
     4381 taatggaaaa agcaggacat gatcatgtcg cattaattac agactgtatg atggccggtg
     4441 ggatgcctga tggaaattac aatttaggcg aatttccagt agtagtaaaa gaaggaacag
     4501 cacgtctaga atctggcaac ttagctggaa gtatattgaa attgaaagaa gcaattaaaa
     4561 atgttgtaga ctggggatta gcaacaccag aacaagcagt catgatggct agtctgattc
     4621 cagcaatcag ctgtaaaatc gatgatacat gtggaaaaat cgctcaagga cgcgatgcag
     4681 actttatcgt attgaaccct gatatgacat tggaagcaac ttatctagat ggcgtggaac
     4741 gtttccacgc ataatataat ttaagttaac cttaaaacta aacttcttaa gtttggtttt
     4801 aaggtttttt ttgtgttcta gtaaaaatca ctttacataa gtttcaaaag tttctttaat
     4861 ttcctattgt tcaataagta acaatgtaaa gataaaatta aaaatgttaa tacgtattag
     4921 caaaataaaa gcttttttta ttgtgaataa atgaacataa ttaggaggag aaagatgaac
     4981 ttatttgaca tttttcgatc gactttgaca gatatgtcga ttgtcagtgc aatcacttca
     5041 acagttttta ttatattatt agggtttgtt tgtagaaaaa aggggatttt ttctgaatct
     5101 gttggaaaaa ttctatcgaa agtcgtctta acagtggctt tgccagcact ggcatttcga
     5161 gctttcatgc aagatatcaa tacagaatta ctgatgcaag gaatcaatgt cttgatttgg
     5221 ggattagtta tttatattat tcttattcta gtttcaaaac cttttttctt aagctataaa
     5281 ggggataagc aaacaacgtt gcgtgtcctg acgatctttg gttctacgac ctttttcgga
     5341 acgcctatcg tcagtgcgat ttatggtcct gtcggcgtga tgtattcctc aattttcaat
     5401 attggctacc gaatcttttt gtattcttat ggatacataa aaatgagtgg cttgaagatg
     5461 gaagctaaaa atatcaaagc gatgttcgtc aatccaatca ttatcgctac ttttgccggc
     5521 cttttcattt ggctgttcca agggtatctg ccacaagtgt cagttacagg tgcagaagga
     5581 gagataagcc aagtagcgtt tttgcgaatt gaccagactg caccgtggct atttcagccg
     5641 atggattatt tagctggttt aagttcacca ttggcgtggc tagcaatcgg cgcaacatta
     5701 ggtgaagtaa gcttcaaaaa agctgcatct gaaaaaactt catggtatta cagtctagtc
     5761 aaagtggtat ttgtacctgc attgaatatc gtgattctag cagttttgac ggcaacgaat
     5821 attctaccag tcaattttga agcactggca acaatcgtta tcatgatggc tacaccagct
     5881 gcaacagtgg cagcagccta tgctatcagt tttgataggg aggcactttt agcctccaat
     5941 gcatccttac tgtcaactat ttttgctgtg gtactgacac ctgtatggat cgttgtatta
     6001 caaatgattc atggcatagg tttattttca taagaaatgg aggaagaaag tatgagaatc
     6061 gcatgttacg gtgttcgtcc gaacgagata gatttttttg aaaaattgaa tatttaccat
     6121 tatgatctca gtctttatga agaactgttg acacatgaca atatcgtgtc agcaaaggac
     6181 catgatgctg tattgttgag gggaaattgt atagcagatg agaccaatct tgcaaaaatg
     6241 caggaatatg ggattcgtta tgtttttaca cggactgtgg gagtcaatca tatcgatcta
     6301 caagcggcag ctgattttgg tatgacagta gcccgtgtac catcgtattc gccaaatgcg
     6361 atagcagagt tatctttgac ttttgccatg atgcttttga gaaatactgc gtatacgacg
     6421 atccgaacat ctttcaaaga ttttcgagtg gatgagcaaa tgtttagtcg tgaaatcaga
     6481 aattgcacag tagggatcat aggaacaggc aggatagggt tgacggaagc tgttttgttt
     6541 aagggactag gagccaaagt gatcggctac gatattcatc agacagaagc tgctaaaaaa
     6601 gtattgacgt tccactcgct tgaagagtta ttagccaaaa gcgatattgt cagtattcat
     6661 gtacctcata tcccaggtga aaacgatcaa atgatcaatg aaggattttt agctcaaatg
     6721 aaaaaaggta gcatcttgat taatacagcc cgtggagagc ttcaagataa tgaagctatt
     6781 ttaagagctt tgaaaagcaa tcatttagct ggttttgcaa ccgatgtttt tgcaaatgaa
     6841 acagaggttt ttttccgatc cttcaagcca tgggagacga ttccagaccc tgctatccag
     6901 caattagtag aaatgtaccc tagagttctt gtaaccccgc atgtaggttc aaatacagat
     6961 gaggcattat caaatatgat ttcgacaagt ttcgagaact ttcgtgaaat aatagaaact
     7021 ggaaaaacga aaaatgaggt atctcttcct aaagcccgtc aattaagata agaaaacatg
     7081 gatattcgtc aataaaatgt ttaaaaatag tccaagtaaa cagttgttac ttctgtatac
     7141 ttggactatt ttgtatggga taattcgatg actcaacagt aatctgtgag ctttttccgc
     7201 ccattctttg tcaattcata acaggttagc ggccggccga tttccaaata tttgattctt
     7261 tcgttcaata tatcttgttc tactaaaaaa ttcaaatatt tcttgacgga tatacgtgac
     7321 agtgagcttt tttgagccag ttcttttgtt gaaaaaatag tatcttcttt tagaataaat
     7381 gcacttattt tttttaaagt cagttttgac agacctttag gcaaatcgat gaatgatggt
     7441 atttcgtgaa tgggagtggt gtggttgaat acttgatcga tcaatttctg atcggctttt
     7501 tcagtcgttt ggattgtctg agagaaagca agatactttt cgatcgccag ctgaaaacgt
     7561 tgcaaagtga acggtttgat caaataatct aaggcaccgt agcggatcac attctttatg
     7621 gtttcgatat catctgcagc agtgatcaaa atcactggga tatcatttcc ttgctgtcta
     7681 agccaagata aaaaatggat accactttcg ccaggcatgt atacatcaag cagcagcaga
     7741 tctgcgtttt tttgtctgaa atattttttt ccttcttcta catttctgaa actttcgatt
     7801 acgttcatat tagggatgct ttccacaaaa gtacgattca attctgcaac cattggatca
     7861 tcttcgatta tcaggacatt tgtcatcatt ttgatcttcc ttttttggta attctagata
     7921 gacgattgta ccgccatttg tttgtttgga aaattctaaa aatccaccgt ggcgtttgac
     7981 gattgaatgg atgagattca atccaaaccc acgattgatt cccttcgtcg aaaaacctag
     8041 cgtaaatatt ttttctgaga tttcttctga tatcccgaca ccgtcatcgc agacggtcac
     8101 gatgaatact tcagcttctg tgtcatagtt taaatgaatc cggacctgtc cgtttctttc
     8161 atgtttttgt agcacggctt cttttgcatt atcaagtaag ttccctaaca cttgcaaaag
     8221 tgaatggatg gagtcatcca tctccatttt agggataaaa gaatcgcttt ctaacagcat
     8281 ttcaacagat tgttctttgg cttcgtttat tttgcctaat aaaaaaccgg caattgcagg
     8341 tactttgatc agacttgaga cttggccaat ctctttttta taattttgat ttagctgctg
     8401 gataaaatgg gtgacttctt catacttctt caaatcaatc aaaccagaaa tgacatgaag
     8461 tttattcatg aattcatggg tttgagctct catggagttt atatattgtt tcgtcccccc
     8521 aagctcctcc attaatttca ttacttctga tcgatttcgt aaagttgcga ctgctcctaa
     8581 aaaacggtca ttgctaaaaa gaggtgtaac gctagaaata gtttctatcc catttaaata
     8641 catggattga gtccgaacgg tcgtttgatg ctcaatcgtc tctttaaaca aaacgtcata
     8701 tagattatca ctgatttttt tcctacttcg aaatccaata gctgctctgt ttggtagaaa
     8761 atgttttttg caggtgtatt gatcaagagg atagttttat cagaagagat ggctaagatt
     8821 ccttcatcta cttcattttc gataatcgtt ttttcactta actgttctgc tatttcttgt
     8881 ggttcaagtc caagcagtac ttttttcatt ttttgggcaa gaaaaacggc gcctatgatg
     8941 cctacgctaa gtccaataat caatgaaaaa acaatcattt tttgtccatc tttgacttga
     9001 ttgtcaatcg tgttgtttgt taagccaaca caaactgcac caataatctc ttgatcataa
     9061 taaataggga cgaaatagcg gaagccgaac cctaacattc cttctttttc agagaaaaat
     9121 tcttgtcctc caatcacttt tttcacatct tcatgacttg agaaaggaag accgatgtaa
     9181 cttgggtctg cgtgagaata tcgaatgcct tcagggtcca tgacaacgat aaaatctaaa
     9241 ttcgatgcaa tcatgatttc atttgttatt ccttgaatcg catgtgtcgg gtcaccagtc
     9301 tgcagctttt tttggatgag tttatcattg gcaacgattt tagcaatgct agagatttta
     9361 tctgacacac tagatcggtt catcgaaaga ataaaattcc tgatcaatat ggcagaaaca
     9421 atcaaagaaa cgaatgtgga gaaacaaacg acaaggatga tcgtgttctg gagctttaat
     9481 ggttttttct taaaaaaagg aaacataggc tacctcgaaa gaatttattg tgaaaatttt
     9541 aacatgaaaa caaaaattta acaaattgtc aacgataaac acaaccttcc tataaaaaac
     9601 accactgagt cggtaaaaga agctatacag aattttcaaa cattggtatg atagacgtag
     9661 aaatggaagg aggcgtgtat atgatagggg gaatcgcact tgagacgatt tattggtata
     9721 cattgctgat ttgtgcagga ttggcagtcc tattgattat ttttggagat gtattcgatt
     9781 ttgatggccc gcttgatccg atgcttatta tcccttggtt aactttcaca agcttatttg
     9841 gttttctagg tgagcgttta acagatcaat catctttatt tttatttatt gctagtggag
     9901 gcatatcgat agtgttggta tttttgctta atttctatat attgatgccg atgaaacatg
     9961 ccgaatcaac gatgtcgtct tctgaaaaaa ctctggaagg acaagtagct gttgtgatca
    10021 caccgatccc tgtacgaggt atgggagaaa ttcagttgaa aagtgttacc ggttccatta
    10081 gtcgtccagc ttgtttttac agcccccaag aacagacagc tgagcgggga acgaaagtat
    10141 tgatcattga gatcaaggaa agaatctgtt atgtcatgcc ttatgaaagc atgataaaag
    10201 cttaaaggag cgtgtgttaa atggaaatac cagttgtttt tatcgcgatc gcaatcgcag
    10261 ctttgatttt actgatgttg ctgatcgtct ttgtagcgaa gtaccagaca gcaaaaccgg
    10321 atgaagcgtt gatcatcagt ggaagttatt taggaagcaa aaatgtgcac attgatgaaa
    10381 gcaataacaa aatcaaaatt gtgcgtggag gtggcgcatt cgtcttgcca gtttttcaac
    10441 gttcgaatcg gatcagtcta ttatcgagta aattggacgt ctccacccct gaagtgtata
    10501 cggaacaagg cgtaccggtg atgtgtgatg gtacttcgat catcaaaatc ggttcatctg
    10561 tagaagagat tgctacagca gcagaacagt ttttaggcaa gacaagagaa gaactggaaa
    10621 atgaagcaag agaagtatta gaaggacact tgcgctcgat tcttggttct atgactgtag
    10681 aagaaatcta tcaaaatcgc gataagttca gtcaaagcgt acaagaagtc gcttctgtag
    10741 accttgcaaa aatggggttg atcatcgttt ctttcactat caaagaggtc agagacaaaa
    10801 acggttatct tgactcttta gggaaaccaa gaatcgccca agtcaaaaga gatgcagata
    10861 tagcagaagc ggaagctcta aaagaaacgc gtatcaaaaa agctcaagca gaaaaagaat
    10921 cacaagcagc tgaattacag cgacaaacag agatcgcaga atcattaaaa gaaaaagaac
    10981 tgaaattagc aacctacaaa caagaacaag atgttgctaa agcaaaagca gaccaagcct
    11041 acaatttaga aagtgcccga gcacaacaac aagtaatcga acaggaaatg cagattaaaa
    11101 tcgtagaacg tcaaaaacaa atcgaactgg aagaaaaaga aatcacacgt cgtgaaaagc
    11161 aatatgattc ggaagtgaag aaaaaagcag atgccgatcg gtacgctaaa gaacaagaag
    11221 cacaagctca aaaagtcaaa gaagttactg aagccgaagc agaacgattc cgtgtggaag
    11281 cactggcaga agcggaagcc aataagacac gtttagctgg acaagcagaa gccgaagcag
    11341 cactagcaaa aggaaaagca gaagccgaag caaaacaaaa gatcgccaat gccttcaagg
    11401 aatatggcga agcagctgtc ttgagtatgg ttatcgatat gctaccgcaa ttgatgcgcg
    11461 aagcagcaca gccgctagga aatatcgaaa aaatctctgt tgtcgataca ggaagcagtt
    11521 caggagaaac cagtggagcg aaccgagtga caaattatgc cacaaatttg ctttcttcta
    11581 ctcaagaaac actaaaagcg acaacaggac ttgacttgaa ggaaatcgta gagaatttgt
    11641 cgacacgtgg gactactagc caagtaaata tgtatgaagc gccaaaagag gcagaacaaa
    11701 actcgatgaa ggaagaataa agtagtacac ttcaccgttc aatcaaaaat ggaggaagac
    11761 tttttaaagt tcttctctcc atttttttat tttattgcaa aagaaaatta gtcctcgcta
    11821 tttttctttt gtttttggat cttagcttct atctcttgta aatttgttct tagcaatcgt
    11881 tctttctttt ggagttcgac caaatcttct gatagttctt ccttcttttc tgtttcagga
    11941 ggacgaagaa agaaattgat accgattgca atgaatgtcc ctataaaagt atctagtaca
    12001 cgttggatag catacaaagc ggattcgcct tgagggatgc tcaacgcaat cagcaacaac
    12061 gtagctattg cggaaatgat accggaatta ttgttaatac catctgacac gacgatcaca
    12121 ataataacta gaataggaag caagatcaat tctaccaaaa aatcattgtg aaaatagctt
    12181 ttgacaaaaa aataaatgat agctaatgta ccacctaatg tattgccgat gatcctagac
    12241 tttccaaaag aaacggttgt agtcaagtcc tgacgcaaag aaaaaacagc agataatgca
    12301 gcaatcatcg ggattcctcg ttgagtcaaa tgaaaaaaca agatacataa aaaaacagct
    12361 aaggcacttt tgatcgtacg catacctagt cgaaaacggc caaattgcat agagattctc
    12421 ctttttggtc tttttactat catacctaaa cttttgtctg atagctagtt tttcattatt
    12481 caagtataat taaaataaaa aagggggaag taaatgcgta taggaatgcg aacagtcaaa
    12541 acagtgatca gtgtcttctt ttcgatggtc acagcgggta gcttatcgct gttgtattgg
    12601 ccagctgcag ggatcattgc attattaagt gtaggaaata ccaagcgctc tacattgcgt
    12661 acgggcatga atcgaatcgc agcctttata ttagctacgg caacagcact gttcagtttt
    12721 tttgctgttg ggtatactat ttttggcttc agtctttttt tattcctgtt catcccgctt
    12781 gcctctcgct tcaaattaac cgaagggata gtagtaaatt cggttttggt cactcattat
    12841 ttagtggagg aaaacatgtc ttggcagctg atcggcaatg aagcgggatt aatggcgatt
    12901 ggattagtat ttgctttgct tgcaaatgtt tacatgccag atcgtacgaa gcagctgaag
    12961 gaaaaccaaa tacagatcga aaaagaattt cgaaatattt tgagacaaat ggcagaattt
    13021 cttttatcag aaaataaaga agatgtgcag atcaaatgcg aacatttact gacattcatt
    13081 cgcgaaagcc aagaagatgc cagagaacat caagaaaact actggctcag acagccgcta
    13141 tactacgaaa cttacttctc tatgagaaga gcacaggcca atgtgattaa agacatgctg
    13201 gaaaatctag agagaatcca gcaaccagct tattatggaa aacatatcta tggtttattg
    13261 atttatactg cagaaacatt ttcagagtca aatgatggca gacaaatttt aacacgtatt
    13321 gaagaagttt atgtattgta tcggcaaatg cctctgccga ctagtcgccc tgaattcgag
    13381 gatcgagcag aattgttcca gtttttgcag tcttttaaaa gttttattga aatcaaggca
    13441 gaattctccc aacaaaaaat ccaaaaatag aggttgtgaa ttcagctaat attcaggtca
    13501 aaaagctgat ttcacaacct cttctttaaa cggtgttctc ctgtcaactc ctcggtcaca
    13561 agtcacaata ttcaacaaac atgagaagct gttttttgaa attgctcctt gtgactcgga
    13621 gctgaacggt aggctcacaa cctctttctt aaacggtgtt caaaagcttt cctctgcggt
    13681 aataagtcca gccaaacgaa aaataggagg agctattttt gtttggctgt tcttattact
    13741 tgatgcagaa cagctttttc acaacctttt aaaattacat atttttccat agaacttgca
    13801 tttgatccaa gatttcgatg acatcttttg tcaagaagag agagcgattg ggcaagtcac
    13861 cttcaatcat gtgtaccata ttctttattt cgtaattcat tgcttcagat gtattcccgc
    13921 tttcgatgaa ttcctttgta ccatctgtaa ataagatctc cgcacgatca gcacgcgggt
    13981 aatcagcaat cgtcacataa ccgttctcaa aggcaacgat accgactttt ggcatttttg
    14041 cctgaaaagt caagctgaca gcagcaagtt cattttcttt gttacgcaag atagtgacgg
    14101 attgttcgtc cacgcctgtt tcaaaaggaa ccattgtaga ggcaactact tcaggttgag
    14161 agctcaaaaa gaaacgagcg aaagatacag catacgtacc gatatccaac agagctcctc
    14221 cagctaattc tggattgaag aaccggtttt tagggtctgg ttctttgtaa ctgccgaaag
    14281 gtgcttggat catttttaaa gcccccagtt ttcctgtatc cattattgag cgtaactgct
    14341 gataaagtgg catgttgaag attgtcatcg cttctgctaa gatcaaattc ttttcttctg
    14401 ctaagcgcat agcgtcagcc agttcttttt tattcatcgt gatggctttt tcacatagaa
    14461 cgtgtttgcc tgcttccaat gctgccaaga tatggtcgat atgctgtcta tttggtacag
    14521 caatgtacac gatgtcgatt tcagcatcgt ctaacatttc ttgatagctt ccgtaagctt
    14581 ttggaatatt gtaacggtga gcgaagtttt ccgctttttc tgaagttctg gaagcaactg
    14641 ctgttagttc gctcgtctct tgattgaagc tttcggcaaa ctcatgtgcg atggtaccaa
    14701 gaccaacgat tccccattga tattttttca tctgaaaacg ctccttcata gttggattga
    14761 gtttcttgtc tgtctattat tataacaaaa atcacgaaga ataaagagga gaggacttga
    14821 aacattaaaa aaaatgaaag cagcgattta agaggtgctt tttgatcaaa acttaagtag
    14881 aatagttaaa aggaggggat aaacgtgcat caagtatata ttgatcttat tatgagtgta
    14941 ttattagaac agtttgaaac tgaaaaaaat tttttagatg aatacttgct gatcagtcca
    15001 gaacaatggc aaaaatggaa agatggcgag aaaaatctgc catctgaagc gatgcagaaa
    15061 gtaaaaaatc ttttcactga ttatgaatgg atgctaacgc aaaagatttt gcgtcaaacg
    15121 attatttttc ccgaaaaacg aaacgttgcc gttgcagagt acaagcaaat caaaacacgc
    15181 atcgcgcaaa aatggcttag cagcaaagca gcaaaagtcg agctgatccc tttgaaaaat
    15241 aatcagcagg ctggtagata ccttgacttg aaagtaagta ttcaatatga tgaatggggc
    15301 tatgatgata ttttgaattt tcgtctgcca gcagatgttc aaaaacagat cgaaggagaa
    15361 aaaatcgaac ttctcgattg ggtgaatgaa aatctggaag aaacttacgt tcatgaggcg
    15421 aatggggaac gtgaagaaca acgaaaggat ttttcaagtg aataaatttt taggatttgg
    15481 agcagttgtg attatgatcg cagcaatggg ctatgttatt tttagcgatg atgattcgca
    15541 tgttcaagcc ggcaatcaag cagtcgaacg aacaagcacc aaaacaactg ctagtaaaga
    15601 aaagaacagt caaacaacca gcagcaaggt aaaggacaaa gaaacaaaag atcgtacgtc
    15661 caaacaattg ccagatgtta aaacagacga ttggaagcta gttttggttg gtccagatca
    15721 caaattagaa aaagaaattg atgagtctac tcaattggca tcattaagta acggatactt
    15781 gatcgacaaa cgcattgctc cagaatatga agcatttgcc aaggctgctg aagcagctgg
    15841 atttccatta gtgatggtct cagcttaccg gtctgtatca tcccaacaac aagttttcga
    15901 acaaaatgtc caagatgtga tgagtcgtca aggtgtatca gaagaggagg cgacaaagat
    15961 tactaaagaa acgattacgg agccaggata cagcgaacac cacacaggtc tggcagtcga
    16021 tgtcgtcgat caaaactggt acaacagtta tccttctact gtattggatg caagttacgg
    16081 agatcagcct ggagctaaat ggatcgcaga taatgctgcg cagtatggat ttatcgttcg
    16141 ttatccaaaa ggacacgaag atataactaa gatcacatat gaaccttggc acttacgtta
    16201 tgtcggtaaa gaaaacgctg agtatatcac caaacaccaa ttgacgctag aagaatatct
    16261 gaatgaatta aatgaaaagt aggaattgat catggcgaaa aaaaagtgga aaaagcaaaa
    16321 gcgcaagaat atccgttggc cagcagtggt tgccggtgta gcagtgatac tcttagcctt
    16381 tgttttttcc ttgaagaatc tgtcttctcc ttttactgat aatcagcaag aaaatgaagc
    16441 gcaatcccat cagcaattta ttgaacggct tgttccgcat gcccaagaac tacaagatgg
    16501 ttatggagtg cttcctagta tcattttagg acaagctata ttagaatcaa attggggaaa
    16561 aagtaccttg gctagcaaat acaataatct tttcgggatc aaggcttatg gggatcagaa
    16621 gaaagtaagc ctggaaacaa aggaatttgt taacgaagaa tggataacta tccaaggaga
    16681 cttcaaagtg tatgattcat gggaacagtc catggatgac catacacaac tgttcgtcca
    16741 aggagtagat tggaatcctg cgctgtatga aaaagtgatt acggccacca actatcagga
    16801 agccgcacaa gcattgcaag atgcaggtta tgcgacagac cccggttatg cgcaaaaaat
    16861 catccaggtc atcgagacgt atcaattgaa tcagtatgac cggagatagc aaaggagaag
    16921 tggctgatgg cagaacaatt tacgccagaa atcatgacgg aattgagaaa agatatcgta
    16981 agagtaccgg aaatcatttt agaagcaagc gggatcaaga tatttggaaa attgatccgt
    17041 tcgatcatct ttactacgga tattgcgatc atacgtaata caaatgcgaa tgcagtaatt
    17101 gctgtgtatc cttttacacc tcatccagcg attactaaaa gcattattga ggcagctgac
    17161 attccagttt tctccggtgt aggtggtggt ttgacacaag gtgctcgttc ttcctacatg
    17221 agcatgttcg cagaagcgca aggttcgtta ggggtcgttt tgaacggtcc tacgccttta
    17281 gagacagtaa aagaagtttg tcgagtagtt gatattccag ttatcagtac ggtaacgtcg
    17341 aaatatacag aaatagatga aaagttagca gctggtattt cgattatcaa tatcagtgca
    17401 ggtaaagaaa ctgcagaagc agtacgccat tttcgtaaaa aatatcctga acttcctatc
    17461 attgcgacag gtggtccaac ggaagaaagt attgctgaga ccattcaagc aggagcaaat
    17521 gccatcacat atacgccacc aagtagcgga gagcttttta gtcgtaaaat ggaaaaatat
    17581 cgggaaactg agaaaaagaa tcatgaataa caggtgagaa tcaaaagacg aggaagagca
    17641 gatagtggct cttcctcgtc ttttgtactc cagtactatt tgttcagaat tcaaaaaaaa
    17701 gagaaatttt tttgtttttt tacctgtaat gtacataaga agagttaaaa ccttttgtta
    17761 ttattagcat tctaacaaaa aaatgtcttg atttattgaa gcgctttcta tagaatgaaa
    17821 aacgaataaa aactaaaaaa ggcacccgac aatttagtag cagctaaatt gtcggggctt
    17881 gaaaagtcag cgggaactga ccaatcaagt tgccatagtc aatgcttgtg catcgacgtg
    17941 tatattgtac ctaatttcat acagaattac tagttatttt tctgtttttt agggaagagc
    18001 gcacacgaag aagcatgctt atttagctat gtcaaggata ttgggcagtt gtctgatatc
    18061 cttttttctt tgcgtaatta tcctcccatc attgaagcaa gaagtgtttt tagcgatgaa
    18121 agaagaatca gcactatcta atttttcttg aaagtattga gttgttcatc ctaggcagaa
    18181 cgataaggca agtcttggtt tttattcccc ttgaaaaaga tcgtttaata aatatgttct
    18241 gtataaaaat acagtatatt gaaaaataac aatggaagta gaggtgcaga gaatgaagaa
    18301 aagaatgaga atcatcttag ctttaagtgt tatgttattc ttcttgacgg cttgtgggca
    18361 agaagatgac aaaaaaatca cgctgaacat ggcttggtgg ggttcgcaag tccgacacga
    18421 tgcaacagta aaagtaatcg agctttatga agaaaaaaat ccccatgtga cgatcgatta
    18481 tgaattttat gattatgaag gatattacac aaaattaggt acactagcag catcagatga
    18541 tatctgggac attttccaac tgaacaatca atttcctcaa tacatcaatc agattgaacc
    18601 attagatgaa tatgtggagc aagggataat tgatatttct aatgcagatg aatcctattt
    18661 agcaacgacg acttacgacg ggcaattagt tggactgtct aacggggtga attcgtttgc
    18721 gattgcttac aataaaaata tatttgaaca attaaatatc cctgaaccag cttcaaattg
    18781 gacatgggat gaatttgaac aaatcagcta tcaaatcact gaagaattag gaatctatgc
    18841 tatttcaaga ttcgaagatt ttatagctgg ctgtattatt caaataccac aagttgagaa
    18901 aggattgaat ttttataatc gggaagatct atctaacagc ttgggatttg aaaatccaga
    18961 ctatctaaca gattttttcc agctgcgtaa aaatctggta gacaaagggg cccatccaga
    19021 accaggtggt ggagctgcaa gtacgacgga tctgtctttt caggcggtta gggatagaga
    19081 agcggcaatg gtgtttctat caagtaacca gttgacagaa atattgtcag gggctcctga
    19141 agatatggag attcagttga ttaatccacc tcgcagaaaa gcagatggag aatctggtat
    19201 ccctttacgt tcttcgcaaa tgctgagtat ggcaaaaagc tcagcccata aagaagaagc
    19261 tgctaagttt attgatttct ttcaaaacag tgaagaagcc aatgaaattt taaaaggaga
    19321 acgtggtgta ccaatcatgt cgaatattcg agaacagctc gctcgtgcag atgatgcaac
    19381 tttgcaagcg acatttgatt atttagaaat gatttccgat atggacaacg gcgaagtgaa
    19441 tgtctttgat agtgctttga atccggaaat tcaagaccaa tacaatcttt tagttgaaaa
    19501 agtcatttat gaagaagtaa cagcagaaga agcagcagag agtctttatg agtttgcgtc
    19561 aaacattcta ggatagcagc aggaggaagg catgaaaaaa gaaaaactaa aacggttctt
    19621 ggatcaagac aatgtggtcg gttacgtatt tgcttctcca ttcatcctag gatttctatt
    19681 gataacagtg ataccgatga tcttgtcact ttattattcg ttcaccgatt atcgtttggg
    19741 aaatccagtc tcatggatcg gcttggataa ttatataaag atgctgagtg atgcccgttt
    19801 tttgaactcc atccgagtca cttttctcta tgtatttgca tctgtacctg tgaaactgat
    19861 ctttggtcta ttgattgctt atcttttaac gaggaatatc aaaggaacga ctttctttcg
    19921 ttctttgtat tatgtgccta gtttgatcgg tggcagtatt tctatcgctc tagtttggcg
    19981 ggagttgttt tctaaaaacg ggttagtgaa tattttcctg gaacgattag gcgcacctgc
    20041 gctttcctgg tttagcgatc aaaaactggt catgatccct cttgttttga tgtctgcttg
    20101 gcaattcggt tcggcaatga tcatctttgc tgcaggtatc aaagagatcc caggctcgta
    20161 ttatgaagcg gcagagatcg atggagcgaa caaatggcag acgttttaca agatcacgtt
    20221 acctcttctt tcgccgatca ttttgtataa cttggttatg cagacaatcg cggcgtttat
    20281 gacttttacg caggcattta tcattaccca aggtggtccg aatgatgcca cgaactttta
    20341 tgctctttat gtgtataacc aagctttttc ttttaattct atggggtatg ctagtgctat
    20401 ttcgtggatc atgctgttga ttatgggagc tgtcaccttt ctgattttca aatcatcaaa
    20461 aaaatgggtc gttgtgtgaa tgagaggagg aagaaatgaa taatacagta acgaaatggt
    20521 ttcaatacgg ttttattttg ctattaggtc tagtcatgat ttatccggtc ttatggatga
    20581 tcgcaggttc ttttaaaacg gatcaagaga ttatgagtgg ttcgctgaat ttgattccag
    20641 agacttttca atgggaaaat tacgcaaaag gatgggcggg gtttgctgga atttcatttt
    20701 ttactttctt taggaattcg tttgtcatct ctgcagtttc gacgataggg acagttctga
    20761 gctcgacttg tattgcttac gcattatcga gaatcgattt caaaggaaaa agattctggt
    20821 tcgtcgtcat gttagtaacg atgatgattc ctgcacaagt gattttgatt ccgcagttta
    20881 ttatttacaa tcggctgaat ttggttggga cgtatgtgcc gctgatttta ccacattttt
    20941 ttggacaagc atttttcatt taccagatca tgcaattcat ggtcagcatc cccaaagagt
    21001 tagatgaatc agcgattatt gacggatgca gcaagtatag tgtctttacc aaaattattt
    21061 ttcctttgct gaaaccttcg atcatcacga cgatcatcat ccagttttat tggaaatggg
    21121 acgacttcat gggaccattg atttatttaa acaagccgag atcttacacg gtatcgattg
    21181 ccatcaaatt atttgcagac gctggatcta gtacgactta cgcgagtatg tttgcgatgt
    21241 ctacgttgtc gctgctaccg gtttttctga ttttcttatt cttcaataaa tatcttgtcc
    21301 aggggatcag tacaagcggt ctgaagggct gaatatgaaa aagccaatag aagagatgtt
    21361 tctttacaag ctcaactact atgtctgtcg gattttttta accagtctta tcagtaatgc
    21421 tcttttcgct ttagttctag gatgtttgtt cactttagga ttagtgctgt ctgctcgtgt
    21481 tgtctatctg atttattttt tgatgatgta tccttcttat tatctatctg tccattactt
    21541 ggcagaaaaa aaggtatgtt ggaggaaagg aaaaatcaaa cggatgtgtt tcatcattac
    21601 gttgtttcag ctgtttgtca ttatttttgc agttgattgg tatttattag tgggaaagat
    21661 tggagcttgg tatctgattc cttttctatt gtgtctgttg ctttttgtat cccatagttt
    21721 ttttagtacg ctaattgata tctgcaaaga agataaagca gatagtcttg tttatttgat
    21781 caaaaggaat atctggctgt tgtcaaaaaa cgtcaagggg tttctgtggt atttatgcct
    21841 tttgtatgga ctgttctggt gtatacagca tgatttttta ctcactgcat tactgtatcc
    21901 agggctgcca tttgtcacag tattttgctt aaaagaaaag gagaatgact ttaaatgaag
    21961 aaaaaatatg tacaagtcgg acttggtggg agagcgcgtt ttttttatga ggcaattgcc
    22021 tctacgtatc atcaaacttg tgaactagtc ggtttttgtg atgtatctca aacaaggatg
    22081 gattatgcaa atcggatact tgtgaacaag tatggacaga aaaaagtaaa gacatgtatg
    22141 ccatcacaat ttgagcaact actggatgac gtacggccgg ctgaagtcat tattacgtca
    22201 gtagatcgaa cgcatcatga ttatatcatt cgtgcaatga aaaaaggata tgatgttatt
    22261 tgcgaaaaac ctctgactat cgatgaggaa aaagctcaag aaataataac ggtccaaaaa
    22321 cagacgggaa gaagcctgcg agtcactttt aattatcgtt atgcaccgta tcacacgaag
    22381 ataaaggaac tgatagaaag tgatgtgatt ggtgatgtgt tttctatcca cttcgaatgg
    22441 ctgttaaata cgcaacacgg ggcagattat ttcagaagat ggcatcgaaa taagcacaat
    22501 agcggcgggc ttcttgttca taaatctacc catcattttg atctagtgaa tttttggttg
    22561 aacagccgtc cccaaaaggt atttgcattc ggtggattaa acttttatgg gatgcataat
    22621 gcggagaaac gcggagtaga aatattttac agtcgatgct atggaagcga actagctaaa
    22681 gctgatccat ttgctataga cctgtcagcc aatgaggaat tgcgagaaat gtatttagaa
    22741 gcagaaaaag acagtggata tattcgtgac cgcagtgtat tttccgatga tatctctatt
    22801 gaagatacac taggcgtaac ggtcaaatat gaaactggtg cgattttgac gtattcgcta
    22861 aacgcgtata tgccgtggga aggattcaat gtttctttca atggcagcaa aggacggatc
    22921 gaaatgaaag tgatcgaaaa gtcttacatc aatgcaggtg gagataaaaa ggatgaagga
    22981 gcagccgttc ttcagtccat ccatgtctat ccgatgttcg gtgagccata tgaggtaatc
    23041 gtcgaacaag aagcgggcgg acatggcgga ggagatccgc gtttattaga tgatctattt
    23101 ggtgaagaaa aagaagaaga tccgtggaat cgggcagcaa ctcacgtaga tggtattttg
    23161 tcgattttga caggaatcgc agcaaatcat tctattgctt caggaaaagc agtagtgatt
    23221 gacgagcttg tcagcttaaa agaataagaa tagatttacg gaaattactt cccgtagttt
    23281 ataaaatctt gccttattgc cgataggctg tcttttgaac actatttatt cggaaaaagg
    23341 ggctatgaca tgctttttgt catgccttct ttttatgtgg gctgcttttt tagataggag
    23401 aaaataaaaa taactattta aacccgaaca aaaaggaata atgcattaaa aatcattaga
    23461 ttttacaaaa aaataagtaa accacgttgt cagtttcaga aagtagtgtt agactgtttt
    23521 caatatttga aacaacattt tttattcaaa tatggcaaac tgccttcacg tgcaaaacag
    23581 ttgcaagaaa atgaatttac actattatta gttttacata cctacttata tatcgtcata
    23641 atatggatga cagtttctag ccagtaccgt aaatgctgga ctataagtaa aagattggct
    23701 atttcaccct tcttttctta tgataaagtg gagggtgttt ttctttaaca gaaacatagt
    23761 aggtttttgc acaaaagcgg ttatttcggt attaataaat gataaaggag caaataaagt
    23821 gaaagaatta gttgaacgta ttcaaaaaga cggacgtata ttaggcgagg gcgtattaaa
    23881 agtcgacagc ttcgtcactc accaagtaga ccctgtattg atggaacaaa tgggaaaacg
    23941 gtttgcagaa gtatttaaag aacaaggaat cacgaaagtt gtgaccattg aagcttctgg
    24001 gatcgcacca gctttatttg ctgcaagaga attagatgtt ccaatgatct tcgctagaaa
    24061 agcaaaaagt ttgacgatgg atgaagaatt attgacagct tctgtttatt cttttacgaa
    24121 acaagtgaca agtacgattt ctatttctcg taaattttta tcttcagaag acaaagtatt
    24181 gattatcgac gatttcttgg caaacggaca agcggcaaaa ggattgatcg aattatgcca
    24241 gcaagctgga gcgcaagtag aaggaatcgg gatcgtcatc gaaaagtctt tccaagatgg
    24301 acgtcagtta cttgaagaaa tgggattgag agtcgtttct cttgcgcgta ttgcttcctt
    24361 gacgaatgga caagttgagt ttcttgagga ggacgcataa tcgtggaaaa agaaacacaa
    24421 aatggaaaag ctgcggtttt agggctgcag catctgctag cgatgtatgc aggagcagta
    24481 gcggtgcctc ttttgatcgg tacaggacta ggctttaatc aagaacagat gacttatttg
    24541 atttcaattg atatctttat gtgtggatta gcgacattat tgcaattgac agttaaccga
    24601 tttttcggaa ttggcttgcc tgtcgtttta ggatgtgcga tccaagcagt agctccactg
    24661 atcttgatcg gaaccaatga aggagtagga gctatctacg gatctattat cgcttctggg
    24721 atctttgttg tgttagtttc tggtgtcttt tctaaaatta aaaaactatt ccctcctata
    24781 gtaacaggaa cggttatcac cgttattggt ttgactttga ttcctgtagc aatcgagaaa
    24841 atgggtggag gtaatgcaac agcagctgat tttggtgaca aaacaaatct gctacttgca
    24901 tttgtgacga ttctcctaat tgtaggcgtg caaatgctgg caaaagggtt cattcgttca
    24961 atcgcggtat tgattggttt agtcggagga agcatcttag ctgctttcat gggaatgatt
    25021 gatctgagcg cgattggaga tgcgccgttg ttccatgttc cacaaccctt ttattttggt
    25081 aaaccaactt tcgacgtatg gtcgatttta ctaatgatca tcatttccat ggtcagcatg
    25141 gtagaatcaa caggtgtata ttttgcactt ggtgacatta ctgggaaaaa tgttggagaa
    25201 gaagaattga aaaagggata tcgtgcagaa ggacttgccg ttatcttagg cggtattttc
    25261 aatacattcc cttatactgg cttttctcaa aatgtcggat tggttcaact ttcgggaatc
    25321 aaaacaagaa aacccatcta tttctctgca ttcttcttga ttgttttagg attattccct
    25381 aaaatcggtg cgttagcaca aatcatccct gagccggtac ttggtggagg aatgttagtc
    25441 atgttcggga tggtggcagt ccaaggaatc cgtatgctgt tggaagttga tttcagcaat
    25501 gataaaaatc tattgattgt tgctgtttct gttggatttg ggctgggttt caatgttacg
    25561 ccgacattat tcagtcaaat gccgcaaaca ttgcaaatgt tcactggaaa tggcatcgta
    25621 atgagtagca ttacggctat catattgaat ttgatcttta atggattgaa aaaagatgaa
    25681 gaaatattgg aagaagcctt caagaagtaa tagagcaaaa gaaaggttgt gaaatcagcg
    25741 ttttgacctg attgttagag aaacaaacgg aaaaatagtt cctcgtattt tgccgtttgt
    25801 ttgagctaat accgagggtc agctgattga acaccgttga aggaagaggt cgtgagcctg
    25861 ccgttcatct ccgagtcaca aggaacaatt tcaaaaaaaa gcttctcatg tttgttgaat
    25921 attgttcctt gtgaccgagg agttggcagg agaacaccgt ttatccataa aaaggaatgt
    25981 gacctaactt ttgtcacatt cctttttttt atctttaata aacacgaaca ataaaatgtt
    26041 tttctttgtt aacattcgaa atttctttga catcaaaaaa agtgattgtt aaaatatgaa
    26101 tgtagaaaaa ctgggaggaa aaacaatgac agcaaaaatc tctgtgatta tggggagtac
    26161 ttcagattgg gaaacaatga aagaagcatg tcaaatattg gatgaattcg gtgtgtctta
    26221 tgaaaaaaag gtcgtttctg ctcatcgaac cccagatttg atgtttgaat atgcacaaaa
    26281 cgctcgaaaa aaaggaatca aaatcattat tgcaggagca gggggagccg cgcatctgcc
    26341 gggtatggtc gcatcaaaaa caactttgcc ggttatcggt gtaccggtcc aatcacgaac
    26401 attaaatggt ttggattcgc ttctttcgat tgtccaaatg cctggaggag tacctgtagc
    26461 tactacagca atcggaaaag cgggagcaat taatgctgga ctacttgcga tacagatgct
    26521 ttccatgtat gatttagaat tggaggctaa attggctgaa agacgttcaa tgttggctaa
    26581 aactgttata gaaagtagtg atcaacttgg ttaaaccttt gttgcctggt tcaacgatcg
    26641 ggatcgtcgg tggcggtcaa ttaggtcgta tgatggcgat tagtgcaaaa gaaatgggct
    26701 ttaaagtagg tgtgctggat cctgtgagcg attgtccagc cgcacaagtt gcagattggc
    26761 acattgaaag tgtctatgat gacacctttg cgctgaaaga gcttgccaga agaacagatg
    26821 tcattaccta tgaattcgaa aacgtcagtg tagaggcgtt aaatgcgatt ttacccatgt
    26881 catttattcc tcaagggaca gacttgcttg cgattacgca agaccgcctg ttagaaaaat
    26941 cttttttgga aacgaataac atcgtgattg ctccttatgc aacgatcgtc agtccgacgg
    27001 atatccaaga tgcgattgac gggatcggct atccttgtgt tttgaaaacc actcgaggcg
    27061 gctatgatgg caaggggcag tatgttttga aaagtcgggc ggatctagct cctgccatgg
    27121 accttttaag agaaggaacc tgtgttttag aagcatggat cccgtttgaa aaagagattt
    27181 cgatcatggt ggcaggaaat ggtcaaggag atttcacgac ttttccggtc gtggaaaaca
    27241 tccaccacaa caatattctt catgaaacga ttgctccagc cgcgattgat caggatgtga
    27301 tcgaggaggc tgagcgtatt gcccgtgtga ttgcagaagc agtgagcctt tcaggtgttt
    27361 taggggtaga aatgttttta acaaaaacag gcgggctata tgtgaatgaa ttagctcctc
    27421 gtcctcacaa ttctggacat tattctattg aagcttgttc tatgagtcag ttcgatgccc
    27481 atattcgagg tatttgtggt tggccattag gagaaaaagt acgtttgata agcaatgcag
    27541 taatggtcaa tgttttggga gaacaactgc tggaaagcta tcgcttgatt gagaataagc
    27601 cagactggca attccatttc tatggaaaaa aacaagcaaa aaaaggtcgc aagatgggac
    27661 atatcactat cttgacagaa gacatccagc aaacgctgga agaaatcaaa caaacgaata
    27721 tttgggatta gaggagaaaa aacatgttag aacgttatac acgccctgaa atggggaata
    27781 tctggacgga agagaacaaa taccgtgcgt ggctcgaagt cgagatttta gcagatgaag
    27841 cttgggcaga acttggtgaa atcccgcaag aagatgtgaa aaaaattcgt gagcatgcat
    27901 catttgatat cgatcggatc ttggaaatcg aaaaattaac acgccatgat gtcgttgcgt
    27961 ttacacgagc ggtttctgaa acattgggag aagaaagaaa atgggtccat tatggtctaa
    28021 caagtacgga tgtcgtagat actgcttatg gctatctcat caagcaagca aatgatattt
    28081 tacgggaaga cttgaaacgt tttacggaaa tcattggcga aaaagcaaaa gaacacaaat
    28141 atacagtgat gatgggtcgg acacacggtg tccatgctga accaactact tttggattga
    28201 aacttgccac atggtattca gaaatgaaac ggaacatcga acgatttgaa catgcggcaa
    28261 aaggagtaga agcaggaaaa atctcaggag cagtgggaac gttcgcaaat atcccgccat
    28321 ttattgaaga gtatgtatgt aaacaattgg ggatccgtcc acaagaaatt tctactcaag
    28381 ttctccctcg ggatctacat gctgaatatt tctcagcgat ggcgcttatt gctacaagta
    28441 ttgaacgttt tgcaacagag atacgcggat tgcaaaaatc cgaaacacgt gaagtagaag
    28501 aattttttgc gaaaggtcaa aaaggttctt ctgctatgcc gcacaaaagg aatccgatcg
    28561 gttcagaaaa tatggctggt ctagccagag tggtgcgcgg acacatggtc actgcctatg
    28621 aaaatgtcac attatggcat gaaagagata tttctcattc ttcagcagaa cgaatcatct
    28681 tgcctgatac cacgatttta ttgaattaca tgttaaatcg ttttggcaat atcgttaaaa
    28741 atctaacggt ctttcctgaa aacatgaagc ggaatatgtc tgcaacattt ggtttgattt
    28801 atagccagcg cgttatgctg aaattgatcg ataagggaat gacaagagaa gaagcttatg
    28861 atcttgttca gccaaaaact gcgtacgctt gggacaacca agtgcagttc cgcccgctgt
    28921 tagaagaaga tccaaccatc acatcggtat tatctaaaga agaaatagac gatgcctttg
    28981 attatcatca tcatttgaaa aacgttgacg tgatattcaa acgagtaggt ttggaataaa
    29041 gaagagtgag ttgcaaaatt caattaaaat agaatagcaa aaataaccaa aaaagaagca
    29101 gatccgttag cggttctgct tcttttagtt tattatattt tcttatcaat aataggaacc
    29161 tgattttaaa agcggctacc tctttaccgt gcctctttac atacaaaaaa tagaggaatt
    29221 aagcgtaaat ggcttggcta ttataactaa aatgctggtt atggagatgt tgcagcaagt
    29281 tttcgagaaa agcgtattcc atctcttgtc cattgaataa gatctggata cgataatgat
    29341 ttttgaaacg cttctgttca tgaatctgac tgattgaaag ttcgcctttg tgttctgtct
    29401 gataaagaaa agtcctttta cggcattcag cacagcgctt ggttgctcgg cggatttttc
    29461 ggaatgtata aaaactagta tctttattgc ataaataaac gtctttgatc gacagcaaat
    29521 cattatatag acaggaacgt tcttcagctg ttaattctga taaaaaaagc tgaccttgtt
    29581 ttattgcatc ttccatcggc aagtgcctcc tcgaacccat tatccaaatt tttagttaat
    29641 tctaatatac catcattaag tataaatgta aacgcttgtt gatggtataa gattttcgtt
    29701 tctgataaaa cacgaacatt aaaagaatct aatgccttaa atgtacatat ttttgttgat
    29761 ttataaaaag atgattgcta aaatttaaag tgaaaaaacg aacaaaaaac gatgtatttg
    29821 cttttaatgt aaataaaaag gagagacgta catggagaag aaagaacttt tgtatgaagg
    29881 aaaagccaaa aaaatatatc ttacttctga tgagaacttg atttggatag aatatttaga
    29941 tcaagcaact gcgttgaatg gcgcgaggaa agaccagata agtggaaaag gagaattgaa
    30001 taatcaaatc acaagtgcaa ttttccgtta tctgactcaa agaggaataa aaaatcattt
    30061 tattgaacaa ttgtctaaaa ccgaacaatt agcaaaaaaa gtacaaatta tccctctgga
    30121 agtggttatc cgaaatattg cagcaggaag tttctcaaaa cgtctaggtg ttcccgaagg
    30181 taaagaattc atcaaaccaa tcattgaatt ctactataag gatgaccagt tggatgatcc
    30241 atttatcaat gaagagcata tctatttctt acaacttgca aagccggaag aaatcagtga
    30301 gctgaaagcc caagcgttgg ctattaatga aattttgacc gaattatttg ctaaggtcgg
    30361 tttggtttta gtagatttca agctagaatt tggccggtcg aatggacaaa ttttgcttgc
    30421 ggatgaagta acaccggata cttgccgatt atgggatgaa cgtacgaatg aacatatgga
    30481 caaagacgtt taccgcagag atctaggtga tttgatccca gtctatcaag aagtatataa
    30541 ccgtctatcg gaactaactg aagaaaagga gcgagtatga tgtatttcgt aaaagtatat
    30601 gtaacctata aagattcagt gttagatcct caaggggagg cagtaaaaaa agcagtccat
    30661 cgtatgggat atgaaacaat cgaagatatc cgaataggaa aatactttga gatacaactt
    30721 gctgatgcag aagaaccaat cgatacagtg attgaaacga tttgtgacaa gctgcttgca
    30781 aatgtaaata tggaaacata ccgatatgaa atcaaaaaaa tggaggaagt ataacatgaa
    30841 atttgcggtc atcgtttttc caggttcaaa ttgtgacgca gatatgttat gggcagttcg
    30901 cgagatcatg ggcgctgatg ccgaatttgt acggcatgat gagtcctctt tagaaggatt
    30961 tgatggggtt ttactgccgg gaggattctc ctatggtgac tatttgagat gcggtgcgat
    31021 tgctcggttt tctacaatca tggaagaagt gattcgtttt gctgaagaag ggaaaccagt
    31081 attcggtaca tgcaatggat tccagatatt gacagaagca ggacttttgc caggtgtact
    31141 gagacgaaat gagtctttgc attttatttg caaaactgta ccattgaaag tcaaccccaa
    31201 gacggccttt acttcagagt atgaagccga cgaaataatc tatcttccag ttgctcatgg
    31261 ggaaggaaat tatttctgtg acgaagaaac acttcaagaa ctaaaaaaaa ataatcagat
    31321 tgcctttact tataatgaca acatcaacgg cagcgtggaa aacattgcag ggattacgaa
    31381 caaagcaggg aatgtgttag gaatgatgcc tcatccagaa cgtgcagtag aagacttgct
    31441 aggatcagaa gatgggaaac ggttctttgc ttccatttta aaaaacttcg gaaaggtgac
    31501 cgtatagatg aaaacattga aagaaccgac agctgaagag atcaagaaaa aaagaatcta
    31561 tgccgaatgg ggattgactg atgaagaata tcgaatgatc gaagaagata tcttaggaag
    31621 aatgcctaat tatacggaaa ctggactgtt ttctgttatg tggagcgaac attgttccta
    31681 taaaaattct aaaccggttc tacgcaaatt tcctactagt ggacctcatg tgttgcaagg
    31741 ccctggagaa ggcgcaggca tcgtcgacat cggtgatgga ctagcagttg tcttcaaagc
    31801 agaaagtcac aatcatcctt cagccgtgga gccttatgaa ggagctgcga caggagttgg
    31861 cggaatcatc agagatattt tcagcatggg ggctcgtcca attgcgttgc tagattcatt
    31921 gaggttcggc gaattagata atccaagaac gaaatattta ctagaagaag tagttgcagg
    31981 tatcggcgga tacggcaatt gtatcggcat accgactgta ggcggcgaaa ttgcatttga
    32041 tccttgttat gaaggaaacc cattagtcaa tgcaatgtgc gtaggtttga ttgaacacaa
    32101 acatatccag aaagggcaag ccgctggcgt cggtaattcg atcatgtatg taggtgcaaa
    32161 aacaggtcgc gacggtatcc acggagcaac ttttgcctca gaagaattta atcaagaaga
    32221 agaacagcaa cgttctgctg tacaagtagg cgatcctttt atggaaaagc tgctgcttga
    32281 agcgtgtttg gaattaatct tgcatcattc ggattctcta ataggtatac aggatatggg
    32341 agcagcagga cttgtttcat ctagtgcgga aatggcttca aaagctggct caggacttat
    32401 attgacatta gatgaagtcc cacaaagaga aactgggatg acaccttatg aaatgatgtt
    32461 atcggaatca caagaacgga tgttgatttg tgttaaatca ggagaggaag aaaaaatcca
    32521 agaactattt cagaagtatg atctagatgc agtcactatc ggtaaagtaa cagacgacgg
    32581 gcaatatcgg ctatatcatc aaggagaaga agtagcaaat ctgccagtcg atgcattagc
    32641 tgaagatgca ccagtttatc ataaagaaat gaaagaacca gctcgaatcg tagaatttca
    32701 gcagttagct ccttatcagc cagttatcga agaacctgga caagtattgc ttgatctgct
    32761 gcagcaaccg acgattgctt caaaacgttc aatctacgaa acttatgatt cacaagtaca
    32821 aaccaataca gttgtccgtc caggaagcga tgctgctgtg atgagggtta gagggacgaa
    32881 taaagcgtta gctatgacca cagactgcaa cgcgcgctat ctgtatttgg atccaaaaat
    32941 cggaggacaa atagcagtgg cagaagctgc tagaaatatt attgctagcg gtggtaagcc
    33001 cttggcgatc accgactgcc tgaactatgg ttctcctgat aaaccagaag ttttttggga
    33061 attatcgact tcagctgacg gaattgctgc tgcgtgtgaa acgttaggaa ctcctgttat
    33121 ttcaggaaat gtctctttat ataatgaaac ggatggtcaa gcaatctatc caacaccaat
    33181 gattggtatg gtcggattga ttgaggatca taaacatatc actactcagg aattcaaaaa
    33241 atcaggggat ctaatctata tattaggtaa gacgtttgca gattttgatg gcagtgaatt
    33301 acaaaagatg cagcttggaa gaatcgaagg tgtgatccga aactttgatc tatccattga
    33361 aaagagaaac caagagttag tattgacagc catccaaaac ggattgattg aaagtgctca
    33421 tgactgttca gaaggtggct tggcaattgc actggcagaa tcagctttca aacatcagct
    33481 agggatatct gtacagtttg aattgtcctc tgctcaatta tttgcagaaa ctcaatcaag
    33541 atttgtgttg acagtcgcac cggaaaataa gacacgattc gaagaaatga tgggagatgc
    33601 tgctgtttta gcaggtaagg tgacggatga agcgataatc gaaatttcag caactgacgg
    33661 tcagatcaaa atagaaactg cagtagcaag aaagtgctgg gaggatgcaa tcgtatgtct
    33721 tatgaagtga agagtttaaa tgaagaatgc gggatcttcg gtgtttgggg tcatccagac
    33781 gccgctagtg tggcatactt cgggctccat agtcttcagc atcgaggaca agaaggtgca
    33841 ggtatcgtgt ccaatgatcg aggaaagctt aaggggcatc gagatttggg gctgctttct
    33901 gaggtattca aagatcaaag aaaattgcag cagttaacag gagaagctgc aatcggacat
    33961 gtacgttatg caacagcagg caatggaagt gtggacaata ttcagccttt tctattcaaa
    34021 tttcatgatc agtcgatcgg cttagcgcat aatggtaact tgatcaatgc tcgttccctt
    34081 agaaaagagt tagaggaaaa tggggcgatc ttccattcta actccgatac ggagatattg
    34141 atgcatttga tccgacgaag tgaagaaaca gattttttaa ataaattaaa aagtgctttg
    34201 aatgaagtca aaggtggctt tgcctattta ttaatgacag aaacggcaat gattgccgct
    34261 ttggacccaa atggttttcg tccattagca atcggacaaa tgaaaaacgg agcatacgtg
    34321 attgcctcgg aaacttgtgc attagaagtt attggggcac gttttataag agatgtccag
    34381 cctggtgaga tagtgatcat caatgacgaa ggaatccaga ttgattgctt tacgaaggac
    34441 acgcagcttt ctatttgttc gatggaatat atctattttg ccagaccaga ttcaaacatc
    34501 gcagggatca atgtgcatac tgcacggaaa aatatgggac ggaatttagc gaaagaatcg
    34561 ccagtaaaag cagatatggt cgttggcgta cctaattctt ctttgtcagc cgcaagcggt
    34621 tatgcggaag ctagtggaat cccttatgaa atcggattag taaaaaatca atacattgcc
    34681 cgaacattta tccagccaac gcctgagcta agagagcaag gtgttcgaat gaaattatct
    34741 gctgtacgag gagtagtgga aggtaaaaag gtgattatgg tcgatgattc aattgttcgg
    34801 ggtacgacaa gcagacggat cgtccatctt ttgaaagaag caggggcaaa agaagtccat
    34861 gtgaggattg cttctcctcc tttgaaatat ccatgttttt acgggattga tattcaaacg
    34921 cgtaaagaac tcattgcggc aaatcacacg attgatgaaa tcaaagaatg tatcggtgca
    34981 gattctttag gttttttaag tgaagagggt ctgatcgaat cgatcggtct ggaaaaagat
    35041 gctccgtatt caggattgtg tatggcttat ttcaacggag attatccgac gccgttatat
    35101 gactatgaag aaaaatatca ggaatcacta aaagaaaaag tatcgttctt ttaaaagcag
    35161 accaagaagg gagtatatga attcaatggc aaatgcatac gcaaaagctg gcgtagatgt
    35221 cgaagctgga tatgaagtag tagaacggat caagaagcat gtcaaaaaaa cggaacgttt
    35281 aggtatgatg ggcgctatag gaggattcgg cggttgtttt gatttatcgg tctttcaatt
    35341 aaaagagcca gtccttgtct cggggaccga tggcgtgggg acgaaattag cagtggcaat
    35401 cgaagcagac aaacacgata caatcgggat cgactgcgta gcgatgtgtg tcaatgatat
    35461 cttagcacaa ggcgcagagc cgttatattt cttagactac ttagcaacgg ggaaaaatga
    35521 tccgttacgt ttggaaaatg tagtaaaagg tgtagcagat ggatgtgttc aaggaaatat
    35581 ggcgctgatt ggcggagaaa cagctgaaat gcctggtatg tactcaggta atgattatga
    35641 tctagccgga tttgctgtag ggatagctga aaaatctcaa ttattgacag gagaaacgat
    35701 caacccagga gatgtgttgc ttggaatagc atctagcggg attcattcaa atgggtactc
    35761 tcttgttcgc aaaattttct ttgagcagca gcagttttct ttatcatcaa aactgccaga
    35821 attgaaaaaa acacttggcg aagaattgct tgagccaacg aaaatctatg tttcttcctt
    35881 gcttccgctg atcaaagaaa agaaaataaa aggagctgca catatcactg gtggagggtt
    35941 tgtagaaaat atcccgcgaa tgttaccaga atctatggct gcacaaatca aacttggctc
    36001 atggccgatt cttccaatat tcggctgttt acaaaaatat ggtgaaattc ctgagatgga
    36061 gatgtatgaa atcttcaata tgggcatcgg tatggtcctg gcagtcgaag aatcgaaagt
    36121 aaaagaaata gtacacgaaa ttgagcaagc tggcgaaaaa gtttatgaaa tcgggaaagt
    36181 gatcgccaaa gaaaaacatc gtgtggtgtt tataggagaa gaacgatgag aatcgctgtt
    36241 tttgcttctg gaaacggaag caactttcaa gcgctagccg attatctatc gaaaaaagga
    36301 ttggaatctt cgattgactg gttgttttgt gatcagcctg aagcatatgt tttgaaacgt
    36361 gcaactgcgt tgagtgtacc ggcagattgt ttttcaccta aagaatttga ttcaaaaaaa
    36421 gagtatgaag aagcaatttt gcataaattg aaagaaaaaa agatcgattt gatcgtatta
    36481 gctggatata tgcgaatcat tggaccggta ttgctgaaaa attatgataa aagaatcatc
    36541 aatatccatc cgtctctttt acctgccttc cctggtttgc atggcatacg tgatgccttt
    36601 gaagctggag taaaagaaac gggtgtcaca attcattata tcgaccaagg tgtagatact
    36661 ggaccaatca tccggcagga aaaagtgaga attgaacagg aggacacgtt cgattcttta
    36721 gaagaaaaaa tccatagagt agagcatcga atctatccag aagtgattag tgaaattatt
    36781 gaaaatggag gctatctgaa atgacaagag cattgatcag tgtatcagat aaaactggga
    36841 ttgtagcatt cgcccaaggt ttgattgaac aaggagtaga aatcatttca acaggaggaa
    36901 caaagcatgc gttggataaa gctgggatca aaacgctttc gatcgaagaa gtgacagggt
    36961 ttcctgaaat gatggatggc cgtgtcaaaa cacttcatcc taaaatccat ggtggtcttt
    37021 taggaagacg cgatctccct agccatatgg aggcaatgga aacggaaaat atccaaccaa
    37081 tcgactttgt ttgtgtcaat ttatatcctt tcaaagaaac gattatgaaa ccagatgtcg
    37141 aaatagcaga agctattgaa aacattgata tcggtggtcc tagtatgctc cgtagtgcag
    37201 caaaaaacca tgaatttgtc acctctgttg ttgatccatc tgactatgaa gaagtacttt
    37261 cagaattacg tcagtatggg catacttcac tttctttcag acaaaaacta gcggcaaaag
    37321 tctttcgtca tactgcggca tatgatgcac tgatcgctca atacttaacg gattgggtgg
    37381 aagaaaaaga accggaaaaa ttgacactta cgtatgaacg aaaacaaacg cttcgttacg
    37441 gtgaaaatag ccatcaagcc gctgcctttt atcagtccgc tcttctggaa aaatattcga
    37501 tcgcagcagc aaaacaactc catgggaaag aactttctta taataatatc cgagatgcag
    37561 atgctgcgct acggatcatg aaggaatatg acgagccaac ggtagtcgcc ttgaaacaca
    37621 tgaatccttg tggtattggg acagcatcta cgattttaga agcgtgggaa gcagcgtatg
    37681 aagcagatcc tgtttcaatc tttggtggga tcatcgtttt gaatcgagaa gtagatctgc
    37741 caacagcaga acagatgcat aagctgtttc tagaaatcat cattgcccct tcttatacac
    37801 aagaagcttt ggaattactg caaaaaaaga aaaacatccg attactgaca gtagactttg
    37861 cgcaggaaga aaatcaaaat cgagaagaaa cggtctcagt cttaggtgga cttcttgtac
    37921 aagatcaaga tctggcaata gaaaatgaag aagagtggaa agtcgtgaca aaacgtaagc
    37981 cgactccagc agaagcaaaa gcattagtgt ttgcttggag agctgtcaaa catgtgaaat
    38041 ctaatgcgat cgtactggca aacgaacgtc agacagtagg aatcggagcc gggcagatga
    38101 atcgagtcgg ttcagtaaaa attgcgattg aacaagcgca agagaaaatg gaaggtgcag
    38161 ttttagctag cgatgcttat tttccaatgg atgattcggt tgaatatgca gccaaacatg
    38221 gtataaaagc aatcattcag ccaggaggaa gcatcaaaga ccaagattct attgatatgg
    38281 cgaataaata cgatctagca atggtcttta ctgatgttcg gcattttaga cattagagag
    38341 gagtcggata aatgaacatt ttggtgatcg gtgcaggtgg tcgtgaacat gcaataagta
    38401 aaaaactttt agccagtccg aaggtggata cggtgtattg tgcgccagga aatccgggga
    38461 tgacaaaaga tggtatcaat tgtgtcgcta tcagtgagcg agatcattca gcgttaatcc
    38521 attttgttaa gaaagaggct attgattgga gtatcgttgg tcctgaagtt cctttgttaa
    38581 atgggatcgt cgatgatttt atggcggaag gattgaaaat cttcggtccg acaaaagcag
    38641 cagctctgat cgaaggttcg aaaagttttg ctaaacaatt aatggatact tatcaaatcc
    38701 cgacagctaa atccagaagt tttgaatgtt acgaaaaagc agcagcgtat atcaaagaaa
    38761 atggtgcgcc aatcgtagtg aaagcggacg gcttagcagc tgggaaaggt gtagtcgtgg
    38821 ctaccacagt gaaggaagcg ctggatgcgg cagaacaaat gttgaaccag catcgatttg
    38881 gggatagtag caaaaaaatc gtcgtagaag agtttttggc aggagaagaa ttctcccttt
    38941 tggcgtttgt ccgtaatacc aaggtgtatc cgatggtcat ttcgcaagat cataagcggg
    39001 catttgataa cgataaaggg ccaaatacag gcggaatggg tgcttattca ccagtaccgc
    39061 aaatttcaaa aaagatgatt gaaaaagctg tggaagaagt tttaaaacca gcggctttgg
    39121 gaatgaaaga actaggacgc tctttcacgg gtgttttata tgcgggtttg attgctacga
    39181 aggaaggacc aaaagtgatc gaattcaatg cgcgtttcgg tgatcctgaa acgcaagtcg
    39241 ttctttctcg gttgaagagt gactttgcgc aagtaatcga tgatttatta gagaatcgta
    39301 cagtagagtt aaagtggcag caagaaggat acaatgtagg cgttgtggtt gcagctgccg
    39361 gttaccccga agaatatgag acaggaatgg ttctaccaga ttttctggaa gaagagcttt
    39421 ctgtttacta tgctggagtt tcctcaaata acggcaaact agttggagca ggaggacgtc
    39481 tttatttagt agaagcatac ggtgagacga tcaaagaagc acagaaaaaa atttacaccg
    39541 cgttaatgga taaaacgaca gatggaacat tttatcgtac agatattgga gaaaaagctg
    39601 ccaatagcga actgatcgtg aagtaaatca gctgcttcca tttataaaaa atacaacaaa
    39661 cataatcgga agcgccgatt ttagtgaagc cttttcataa agagtgtggt acacttttgt
    39721 tgtgtatata aataaggagg agttcagatg aaaaaaattc aattaggtac ttctgatcag
    39781 aaagcagctg cagtgatctt aggctgtatg cgtatcaaca atgcggaaga tccagtaaaa
    39841 gtgattgaga cagcttatga aaacggcatt gatttttttg accatgcaga tatttatgga
    39901 aacggtgaat gtgaagaaat ctttgcagat gctctagcaa aaacatcaat caaacgagaa
    39961 gatcttttta ttcaaacaaa atgtggaatc gttccaggtg tgatgtttga tttttctaaa
    40021 aaacatatca ttgaatctgt agaaaaaagt ttgacccgtc tgaaaatgga ttatgtggat
    40081 gctttacttc ttcatcgtcc agatacattg gtagaaccag aggaagtagc tgaagcgttt
    40141 gatgaattgg aacggtcagg aaaagttcgt tattttggcg tcagcaatca aaaaccaatg
    40201 caaatcgaat tgctgaaaaa atatgttcgt caaccattag tagctaatca gctgcaattt
    40261 ggcttgaaac atactggaat gatcgatcaa gggattcatg tcaatatgac agatgaagca
    40321 agtatcgatc atgacggtag tgtacttgat tattcccgat tgcatgatat gacgatccaa
    40381 gcatggtcac cataccagta tggatttttt gaaggtgtat ttatcgggaa cgaaaaattc
    40441 cctgaattaa accaaacatt agaagaacta gcagctaaat atcaaacgac accaactggc
    40501 ttggcttctg cttggatttt acgccatcca gccaatatgc aagtgatcgc cggtacgatg
    40561 aacgtagggc gaatcaagga aatcgctcaa gcttcagaaa ttaatatgtc tcgggaagat
    40621 tggtacgaat tgtaccgtgc tgctggaaac attttacctt aaagattgtc ataagcaggt
    40681 caaaagggct ataaattaaa aagacagaat aacttgaaag ctgttttcag cttcgagata
    40741 ttctgtcttt ttttattgca aatggaaaga gtatcattgt acggatttcg tttattagtt
    40801 atttttgttt ttaaggaaaa gctgtgtccg atattctttt ggagaaatcc cttgtttttt
    40861 cttaaataaa taactgaaat agttagggtc attataacca atttcaaaag caatatctga
    40921 aatacgatag tctgattgct gcaataattt ttttgctaat tcgattcttt gttctgtcag
    40981 ataatcgatg aatgtttggt taaacgattg agaaaaaatc gtactgaaat gagagggact
    41041 taatgcaact tgttgagcga cccaagttaa ggacatatct ggatcggtaa aattttcttt
    41101 gataaaatcc aatgcatggt tcaaaattgg ctgatatttg ttccttgaag gctgtgaggg
    41161 cagagcagtt aagaaagaaa tgaacatata aactgtcgaa cggtaaagcg agtcgtcggc
    41221 gctgattgct aagcgttgac tggtggatgt gcaatgaacc atttcttgcg ggattttctt
    41281 ttctttcagg cagacatgct ggagtagctt agtcaagaca aataaacgat ataatcgtgt
    41341 tcgagttggt gtgccttgtg gtttcgtcaa gtgttcgatg tacttagata cttcgttttt
    41401 cgataatgaa gacaaatcaa gtgagaggtc aaagtaaaag acagaatcaa ctggaagttt
    41461 cgcttcttga atcaaatcct catagctgat aatttgttct ttaagggaac tggcggtttc
    41521 aagtatcatc tgcgtgatct caaaagatgc aggtaattcg ctgattcttt ctgcgacagg
    41581 accaatggcg acagaaaaat tatttttttg tcccttttct aattcatgga ccaacgtttg
    41641 ggctacctga taactggtct cgatcacatt ttcttcaaga gaatcaacta ttaaaaattt
    41701 gatgaatcga gaggaaacag cagagaagat cacttgttga ttctccctaa ataaaaactt
    41761 caaataatca ctgagatgag cgtaatcttc aaagtctgta ctgacttggt ttgctgctaa
    41821 taatacggtc atttttttcc ctgctaaaga gcgattgaaa gattcagcaa gtttcaatgt
    41881 ttcactgatc gtaagtgagc ctttgaacaa accgttcaag aaatgatttt ttttcaattc
    41941 gaaaacaaga tcagaagaag tgtgcgtttc tttttgctgc aaatctaaag cagttactgc
    42001 tttttctatt gcttgtttca attcgctact tttaatcggt ttaagcagat aatcatctgc
    42061 ctgtacctgg attgctcctt tcatataatc gaaatcgtcg aatccactaa taaatatgag
    42121 acgagtccaa ggaagtagtt tccttgcttc ttttgaaaaa gtcaacccgt ccatgaaagg
    42181 catttggata tcagtcagaa tgatgtcggg ctgtaagtcg ataattgaag acagtgccat
    42241 ctcaccatct ccagcttcgc cgacataagt gattggataa taagaaccaa ggacagttat
    42301 ttgttcccgc aagttattgc gaatgaggta ttcgtcttcg atgataaaaa ctttatacat
    42361 gtttgtttcc tccaattgtt ttgggagata gagggatcat cagtgtgaca gttgttcctt
    42421 ctcggtattt gctgtcaatc gtgataggtt tttgatcatt tccgtaataa agaaggagac
    42481 gcttgtttac gttgtaaagt ccgtagccga tactgaaatc tgaatcgatc cctttggcta
    42541 actctttacg tatttctgcc agtttttctg cagggatgcc aatcccgttg tctataactt
    42601 tgaattggat catctcatca attttgcatg tggtaatacg aataaatcct ttgtgacgga
    42661 cgtacttcgt tccatggtat acagcatttt caatcaatgg ctgcaagatc atttttaaaa
    42721 tagaaacagg aaaaagtgtt tctggtatat cgatcttata gtcaagcata tggccgtatc
    42781 ttatttttaa gatgactaga taatcattga tatggctaat ttctttttca agaggaatcc
    42841 agtcttgtcc tttgcttaaa gacgtacgaa aaaagccgga aagtgcatgg gtcatagtca
    42901 gagcttcttc aaagcagtct tgttcgatca aagaaataat ggcatccaaa ctgttataaa
    42961 taaaatgggg agtaatctga gcttgcaata cacgaacttc actttgtgct aaatggtatt
    43021 gtttcaaagc gttctcccgt aaagactggt ttagatcttc cgccatttta ttcatgctag
    43081 cggtaagtgt ttgtaattcc agtgtttccg gcagggttaa acgaaagcca aggttccctg
    43141 aagaaagttg ttctgacatc tcgatcagct gattgatcgg ttcttggacc tttctctcta
    43201 aaaagcgacg attctttttc gcatagaaaa aaatggtact aagaactcca agttccacta
    43261 ttgttaatag aatgagcgag cggacaagtg tcgtattttt tttgcttgct aagtcgatct
    43321 ccacacgaac aaaatcttgt aagatatctg acagcagttg agtgacagaa tctacctgat
    43381 tgatgatctc ttcattggta tccataaaat cttttgccaa gatattattg atcagctcgt
    43441 tttgataatc ttccagtgta tcgatcgtac gtagcgatac atctaacgta ctaatttctt
    43501 taagtgtatt tgtattattt ttgatctctc gaatatcatt cctaagttct tctaggatat
    43561 tttcctcatt gaactcatct acggttactt ggccagaaat caagtcccac atactttcca
    43621 aaactttttg atcaaccttc aaagcaattg catctgcttt ttggatattt gcgatcgtct
    43681 gttgataaat caaaagctgt tgcgaatata acagtatgct cagtagcaaa gggataacag
    43741 caaatagaag catggctttg tttgcttggg caaaaatctg ttttatgctt aaattttttg
    43801 tcatgatact tctccagtca ataatttctg gttgggatgt tagctatatt ctgctgggaa
    43861 aagacagtct cggaaataaa aatatcttta ggtaatgttt ttcctgtttg aatatttcca
    43921 aaataacgag taacggtatt ggctacatac cagccgacat caggtttaca ctcgactaca
    43981 caattgacga ttcctgagcg tagcttctcg atcatatctt cttgtccatc aatagttaca
    44041 atgatcaaat cttctccagg tttgattgat gtttctttta tcgcagctaa agcaccgtga
    44101 gtcatttcat cactatggct gtataataca tcgatttcgg ataaatcatt tgtttctaaa
    44161 tatcgtttca tctggtcttt tcctttcatc cgaataaaat caccgacaat tcggtgaaca
    44221 atagtcatcg gaggtttatg gtcgatggtt ccatcttttt ttagggttgg tttacgattg
    44281 attgattcca aaaatccttc ggagcgtagc ttggtcggtg tggagttctc tgaaccagca
    44341 agttctagga ttctgatttc ctgtttcttt gaatttgtga agtgattgct gacaaataaa
    44401 cccgcccgat ttccttctgc tttgaaactg gggccaatgt gggtgacgaa aagctcggga
    44461 tcattcgttt gaatatgtct gtcgacaagt atgacaggga tccctgctcg ctttgcttct
    44521 tttaatacag agtcccaccc ggattcttgc aaaggagtaa aaatgatcat atccacttta
    44581 taggcaatga acgtccgtat atcttggatt tgccgttcct gattcatgta gccatttcgg
    44641 tagagaactt ggtaatcttc tttttcaagc gcagtgataa ttgattcagt atgctttttc
    44701 cgccagctac tctccgttcc tgattgcgaa aaaccaacga ctagtgggtc aggtgcttcc
    44761 tttgtattag gtgtacaccc catcatttgg taagcgatta caacaagggc taaaaaaaat
    44821 aaaacacgtt tcactttaaa tcactccatc tggatttgtt agtactatct tatcagataa
    44881 aagggaaaat caaagtcaaa aggaatcaat cgaaaaaaat ccaagaaact taaaaaaatc
    44941 caagacaaaa aaagtacacc taaaaaattt aaagtaaatc ccataaaaaa atcaatgtta
    45001 acgctttctt tattagctat actcggtgta tcaattgaaa tgggggataa aaaatgaaaa
    45061 acaaatttag aaagattgtt gggactatcg ctattttgac cgcaagcatt ctattaagtg
    45121 cgtgtggcaa ttcaggatct gcagatgata gtacggggta tgtaggaatc gctatgccga
    45181 ccaaatcagc agaaagatgg atcgctgatg ggaacaacat ggtctcggaa ttagaaaaac
    45241 tgggttataa aacagatctt caatatggag aagataaagt agaaaatcaa gtagcacaaa
    45301 tagaaaatat gattacaaaa ggggtagata cacttgtgat tgcttctatc gatggttcgg
    45361 ctttaactga tgtgttagct aaagcaaaag aagcagatat caaggtgatc gcctatgatc
    45421 gtttactgat gaattcagaa aatgtcgatt attacgcgac ttttgataat tttggagtag
    45481 gtgtatcgca agcagcttat attgaagagc acttaggatt gaaagaagga aaaggaccat
    45541 tcacgattga attatttggt ggctcgcctg acgacaacaa cgcactaatc aattacaacg
    45601 gagtgatgtc tgttttacaa ccatatatgg acaacggtca gttggtcgtg ccatctggac
    45661 agacgagttt cagtcaaatc gctacgcttc gctgggatgg ttctacggcg caagcaagga
    45721 tggataatct gttaagcgca aattatactg accaaacatt ggatgctgtt ttgtcgccat
    45781 atgatccaat aagtttagga atcatttcgt cattaaaagg cgtggggtat gggagtgaaa
    45841 gtaaaccttt acctgtgatt actggacaag atgcgacagt tgctggcgtt aaatcgatca
    45901 ttgccgggga acaaacacaa acgatcttta aagacacacg tatcttagca aaaaatacga
    45961 ttgaaatgat caaagcaatc agtgatggag aagaggttcc ggtcaatgat actgaaactt
    46021 atgataatgg ggtgaaaact gtccctacgt atttagcaaa tacagtatct gtcgataaag
    46081 ataattatca agcagagctg atcgacaccg attattataa agaatccgat ctgaaaaatt
    46141 aagaggaacc aaacaaggaa ctaaagagat ctaagtcaga gagaggataa gaattatggc
    46201 ggattgtatt ttaaaaatgg cagatatcac caaaaaattt tctggaatcc gagcgttaga
    46261 ttgcgtgaat ctgatgattg aacgtgggga aatccatgca ttgtgcggag aaaacggagc
    46321 gggaaaatca acattgatga atgtcttgag cggcttgtat ccatatggct cctatgacgg
    46381 ggaaatcttt tatgatggaa agctgtgtca atttaaagat ttgaaagata gtgaagaaaa
    46441 aggcatcgtc atcattcatc aagaattagc actaagtcct tatctttcaa taaaagagaa
    46501 tatttttctc ggaaatgaac aagcagaaag aggcgtgatt gattgggaac tgacagaaaa
    46561 gaaaacatat gaactgctga ataaagtcgg tttgtctatc gacccgaatc ttctagtatc
    46621 ccagattggc gtagggcaac agcaactagt tgaaatagct aaagcattat caaaatccgt
    46681 ccgtctgttg attttggatg agcctaccgc tgcattgaat gaagaagaaa gcgcgaattt
    46741 gctgagattg atccgagagt tgaaagagca aggtgtaacc tccatcatta tttcacataa
    46801 gctgaatgaa atcgtggata tcgcagatcg aatcaccatt ttacgggatg gacagacgat
    46861 tgagacacta gaaaatgaaa tgatcagcga agagcatatt attcgcggaa tggtgggcag
    46921 agatttagtt gatcgttatc ctgaaagaaa accggatatt ggagaagttt attttaaagt
    46981 agaagactgg acggtctatc accctcttga tcacgagcga atcataaacg accacatcaa
    47041 cttgcatttg aaaaaaggag agattgtagg aatagctgga ctgatgggag cgggcagaac
    47101 tgaattcgct atgagtctat ttggacattc ttatggaagc aagatatccg gacgtatatt
    47161 aaaggaaggg gcagagatat cagttaagac cgttccttca gccattgcaa acggactcgc
    47221 ttatgtctcg gaggaccgaa aatctttagg actgaatctg ctgatggata ttcgggaaaa
    47281 cgtgacgctg agcagtttgg ataaaataag tcaaaaagga gtattagata aagaaaaaga
    47341 agtaactgag gcagaaaatt tccggaaaaa gatgcgtata aaaacaaact ccatccatca
    47401 aattgtcagt agtcttagtg gtgggaatca acaaaaagtc gttttatcca agtggctgat
    47461 gacacaaccc gatattcttt ttttggatga gccaacccgt gggatagatg ttggggcaaa
    47521 atatgagatc tacacgatta tcgaagaaat ggcagcaaat ggcaaagctg tctgtcttat
    47581 ctcttctgaa cttcctgaaa tattagggat gtgtgatcga atctatacga tgaacgaagg
    47641 acgtattaca ggagaagtct cgcgagaaga tgcagatcag gaagtcttga tgaaattaat
    47701 gacgaaagaa gaggtgggtt aagttggaac aggcaaaaaa tcttacggat aaaaaagaga
    47761 aaaaactaaa tttgaaaagt agagcagctg atctttttgg tcgctacagc atggtgatca
    47821 ttttagcggg actacttatt gcgtttcaat tgatgacgga tggtattttc tggcgtccat
    47881 tgaatataac taaccttgtt ctgcaaaata gccatatatt agtactagct gcagggatgt
    47941 tattagttgt gctcttaggt catgtggatt tgtcggtagg gtcagtgatg gcgtttgttg
    48001 gtgcaattgc gggcatgatg atggtcaatc gccaaatgaa cccgtggatg acagttatcg
    48061 catgtcttgc agtaggcggg ctgatcggcg catggcaagg tttttgggta gcttatgcag
    48121 ggataccggc gtttatcgtg actttagcag gattgctgat gtttcgtgga ctgacacaag
    48181 ttgttctagg aggccaatct ctagcacctt ttccagctgt tttccaaaaa atgtctacgg
    48241 gttatttacc agacttaagc gaaggaagca gccttcactt cttgacattg attttaggaa
    48301 tgatcatcac gatcgtgtta gttgttggtc aatggcgaac aagaaatcgt cggaaaaatc
    48361 atttatttga agtggaatct ccaacagctt tcttggtaaa ggcggtattt acagcagtcg
    48421 ttgtactagg aataacttat atctttgcct cttatcaagg gtatccgatt attttgatca
    48481 ttcttggttt gatcgttgca gcatatgggt ttttgacaaa taaaacagta gcaggtcgac
    48541 agatttatgc gacgggcgga aatcgaaaag cggctgaact atcagggatc aaaacaaagc
    48601 gaatcacgtt ctgggtattc gtcaacatgg gagtcatggc agctttagct ggattagttt
    48661 tagctgctcg attgaatgcg gcaacacctc aagcaggtac atcgatggaa ctggatgcaa
    48721 tggcggcagt atattttggt ggtgcttcga cttccggcgg cattggaaca atcatgggtg
    48781 cgattgtcgg tggcttggtc atgggtgtat tgaacaatgg catgtcgatt ttaggcgtcg
    48841 gggtagactg gcagcaggca atcaaaggat tgatcttgct tttagccgtt gtgctagact
    48901 tgtataataa gaaaaaacga acaacgtagg agaacgccgg ttattcagaa aaaagactgt
    48961 gacaagacat ttgtcacagt ctttttttcg ctaaaagcga acattcattg tttcgtttgt
    49021 atagactaaa aataatatat gtttttttac cattcgtata aattctcttt ttgctcttga
    49081 tttttttgct taattgagtt aaattacata gggcgctaaa aaaagccttg attaaattaa
    49141 taatgttcgt gttttgctgg atgtgaacat caggaggata atgtaatgaa agtatttgat
    49201 tacgaagata ttcaattaat tcctaataaa tgtatcgtaa atagccgttc tgaatgtgat
    49261 acaacggtca cattaggtaa acatacattc aaaatgccag tagtgcctgc caacatgcag
    49321 acgattattg atgaaacaat cgcagaattc ttagcggaaa atggttattt ctatatcatg
    49381 catcggtttg atgaagcagc tcgaattccg tttatcaaaa aaatgaaaaa gcgtggattg
    49441 attacctcga tcagtgttgg cgtcaagaaa gaggaatatt cctttataga gaagttggca
    49501 gaagaatcgc taaatcctga ttatatcact atcgacatcg cgcatggaca tgctaactca
    49561 gttattgata tgattcagca tattaaaaaa tatttgcctg aaacttttgt gattgccggt
    49621 aatgttggta caccggaagc cgtccgtgaa ttggaaaatg cgggcgcaga tgcaacaaaa
    49681 gtcgggattg gtccaggaaa agtatgtatt acaaaaatca agacaggctt tgggactgga
    49741 ggctggcaac tggcagctct tagatggtgt gcgaaagcag ctcgcaagcc gatcatcgct
    49801 gacggtggga tcagaacaca tggcgatatt gcaaaatctg tccgttttgg tgcgacaatg
    49861 gtcatgattg gttcattgtt tgccggtcac gaggaatctc ctggcgaaac aaaagtcgaa
    49921 aatggaatcg tgtataaaga atactttggt tctgcttcag aattccaaaa aggcgaaaaa
    49981 cgaaatgttg aaggaaagaa aatctggatc caacacaaag gatctttgaa agatacacta
    50041 gtggaaatgc aacaagacct tcaatcatct atttcttatg ctggaggaag agatctggaa
    50101 gccattcgaa aagttgacta tgtcatcgtg aaaaattcga tttttaatgg agacacaatc
    50161 taaaaaataa ataaaatatt aggatgttgt gaaaaagttg tcctgcatta agtaataaga
    50221 acagccaaac aaaaatagtt ctttatatgt tttgtttggc tggaattatt atcgcagata
    50281 caagcttttg aacatcatta ttcagaataa gggactgtga taagattttt gtcacagtcc
    50341 cttatgtttt gcaaaaaaag tttttctttt ttctcgtaaa ttcggtaaaa tcaaaagaaa
    50401 aaatagacaa tagaaaagag aagcttatgt gggaaaaagt agagaaaaaa caaggaccga
    50461 tttatcgtca aattatggaa cagattatga gagaaatcga aaacggaagg atcaatcctg
    50521 gaagtcaact tgaatcagaa cgaaaactag ggcaactttt tggtgtgaat cgttccaccg
    50581 ttgtccatgc attggaagag cttagggagc ttggggtact aacgagcaaa cgtggcagcg
    50641 gatggtttgt taatcagact gaatggggga aattcgctgt tccaagaatc gattggcggc
    50701 aaatgatctc tcctcgttat gagcagacgg actggtatga gcaaaaaata agagaagcaa
    50761 agcagatcca aaaaacatcg tttcttgatt tatacgctag cgagatgcca gatgagcttt
    50821 tgccgaattt tgagtttcct tcttattctc ttgaagaaat cttagcggaa gaaaaagaaa
    50881 tggatctttt aggctatact ccgttacgta acaaaatcaa acggtatttg gaaagtaaat
    50941 ttgaattggc attttccccc aaccagcttc ttgtgactgg tggcggtcag caagcaatct
    51001 ttttgatttt acaaacgatt ctttcagctg gagaggggat agctgtagag tcaccttctt
    51061 ttttttaccg attacctctt ttcaaagctt caggaacgcg tttatttggg ataccgatgg
    51121 atgaagaagg gatcgactta gaaaaactga aagaatcgat ccataaaaat aaattgaaag
    51181 cagtgcttat caacccgaat tttcaaaacc ctacaggaaa agtgatgagt caaaaacgac
    51241 gagaaaagct agtagaattg tgtcgacagt atcggcttcc aattattgaa gacgatgtat
    51301 ttacggatct ttcatttcta aaccaagaag aagtccttcc tatacgaacg attgatccgg
    51361 ataatgtgtt atacgtcggt tcgttatcta gggttttagg aaaaacaacg aaaatcggtt
    51421 gggtgatagg acctgagact tttatctcgc aactagctca agcgcaagaa atgatggagt
    51481 tttcgatgaa tatccttaca caaatcacag tggctaatgt atttaatgaa gcaattgatt
    51541 tgaaaatgca agatgtaaga aaaaagttga aagaaaaaag ccgactgata agcgcttggg
    51601 gagattcaca atcgtttttc aagcttcatt caattttagg tggttactat gcctggatta
    51661 cttgggatgg gaaaaaacta gaccccgaac tagcagaaaa agtagtagat atgggtcttg
    51721 gaattgcacc aagtctactt tttgggcaag atataaatgg aatcagaatc aattacagta
    51781 ggctggatga aaaccaaata ccgttgtttt attcaaagat gaaaattcta gaaaagtggt
    51841 taacagaata atttcacaaa gtaaatagat taaagaatat aacagcttgg atttaaattt
    51901 caagctgttt cttttttttc ggaaaaagaa tacgatataa agaaactaag aaaaaaccat
    51961 tatttgtacg tccgttcacg atgtgtaaat aaaataaatg tttgcaacaa aactgtataa
    52021 caccaacgtt tttaaataga aacagatggt tgtaagtttg attagaaaat agaaaaaatg
    52081 cagatgaaat ataaaacgct ttccttattg tgattttatt cactaatgct gttaatatgc
    52141 ggattggcat aatttccttt catcgtgaaa atttgtgctt ttagcttgta tttctcataa
    52201 atccatgata atttattaat gaagacggtt aaatagtgat acagttttat tcactgtttc
    52261 aatcgcagaa tgaagagatt ttcttataga tgagagagga atgtgtgaca aatggcaaac
    52321 aaaaaagcac cgatcgactt ccaagcactg ctagatgaag tcaatgcaga tttcccagta
    52381 tatcaagcac ttgatcaaga tggaaacgta gttaacaaag atttagtacc tgatttatcc
    52441 gatgatgaac tcgttgaatt aatgactcat atggtatggt ctcgtgtatt agaccaacgt
    52501 tcaacagcgc tgaaccgcca aggacgccta ggcttttttg caccaactgc tggacaagag
    52561 gcaagtcagc tggctagtgc ttacgcattt gataaagaag atgttcttct tccaggttat
    52621 cgggatgtac ctcaactagt aaaacatggt ttacctttat ctcaagcttt tttatggtct
    52681 cgaggacatg ctgcaggtaa ttcttatccg gaagaattga aagctctacc accacaaatt
    52741 atcatcggtg cacaatatgt acaagcagcc ggtgttgcat taggtttgaa gaaacgaaac
    52801 aagaaaaatg tcgtcttcac ttatactggt gatggcggtt catcacaagg tgatttttac
    52861 gaagcaatca atttcgctgg cgcttaccat gcaaatgccg tattttatat ccaaaacaac
    52921 gggtatgcga tctctacacc tcgtgaaaaa caaactgcag caaaaacact tgcacaaaaa
    52981 gctgtcgcag ctgggattcc tggtattcaa gtcgatggaa tggatccgct tgcagtatat
    53041 actgtatcta aaatggcacg ggaatgggcg atcagtggaa atggaccagt cctaatcgaa
    53101 acactgactt atcgttatgg accacataca ctatctggtg acgatccaac ccgctaccgt
    53161 acaaaagaca cagatgacga ttggcagaaa aaagatccat tgatccgctt ccgtaaatat
    53221 ttgacggaaa aaggactttg gtctgaagaa aaagaagaac aagtcatcga agcaactaaa
    53281 gaagaaatca aagcagctat tgctgaagcc gacaaagtac caaaacaaaa ggtttcagat
    53341 ttcttgaaaa acatgttcga agtatctcca caatcaatca aagaacaaat tgcaatttat
    53401 gaagcgaagg agtcgaaata atcatggcac aaaaaacaat gatccaagca atcacagatg
    53461 ccttagcact tgaactagaa aatgacgaga atgtcgttgt ttttggtgaa gatgttggga
    53521 aaaacggagg agttttccgg gcaactgaag gattgcagga aaagttcgga gaagaccgag
    53581 tattcgatac tcctttagct gaatctggaa tcgcaggatt gagtttcggt cttgcgttag
    53641 aaggatttcg tccagttcct gaaatccaat tctttggttt tattttcgaa gcaatggacg
    53701 aagtagtagc tcaaatggct cgtacaagat atcgaatgag cggcactaga aatctaccca
    53761 tcacaattcg ttcgccattt ggtggcggtg ttcatacacc agaattgcat tcggataatt
    53821 tagaaggttt gatcgctcag tctcctggta ttcgagtagt gattccttcc aacccttatg
    53881 atgcaaaagg actattgatt tcttctatta gaagtaacga tccggttgtt ttcctagaac
    53941 acatgaaact atatcgctca ttccgagaag aagtgccgga tgaagcttac gaagttcctt
    54001 tggataaagc agcagttact cgtgagggaa cagatgtatc tattatcaca tacggagcaa
    54061 tggtgcgtga agcaatcaaa gcagcagaca atcttgcaaa agaaaatata tctgttgaaa
    54121 tcattgatct tcgtacagtt gcgccattag atgtagaaac gatcattcaa tccgtggaaa
    54181 aaactggtcg cgtagttgtt gtccaagaag cacaacgaca agcgggcgtt gccgcgcaag
    54241 tagtttctga gatctcagaa cgcgctatcc tttcattaga agccccaatc ggacgagttt
    54301 ctgcacctga tacagtcttc ccatttggac aagcagaaaa tgtctggttg ccaaatgcaa
    54361 aagatatcga agacaaagta aaagaaatcg cggaatttta agaaaagaag ggacgaaaca
    54421 aagtcatggc ttatcaattt aaattgccgg atatcggtga aggaatcgca gaaggtgaaa
    54481 tcgtcaaatg gttcgtcaaa ccaggagata cgatcaatga agatgataca ttactagaag
    54541 ttcaaaatga caaatcagta gaagaaatcc cgtcacctgt tacaggaacg gttaaaaatg
    54601 tgattgttcc agaaggtacc gtagcaaatg ttggggatgt attagtagaa atcgatgcac
    54661 caggacacga agacaatgaa ggggacagtg gtgtagccgc agaatcccaa actccagcta
    54721 aaccggctgc tgaacccact gttgatacag aatcagctgg atcgtcaagc gaaggagtct
    54781 tccaatttaa gttaccggat atcggtgaag gaatcgcaga aggtgaaatc gtcaaatggt
    54841 tcgtcaaacc aggagatacg atcaatgaag atgatacatt actagaagtt caaaatgaca
    54901 aatcagtaga agaaattccg tcacctgtca cagggacagt taaaaacgtg attgttccag
    54961 aaggcactgt agcaaatgtt ggggatgtat tagtagaaat cgatgctcct ggacacaata
    55021 gtgcaccgtc aactagtgcg ccatcagctg aagcaccaaa agaaaaagtg gaaacatcag
    55081 gttcagcaag tgtcgttgaa gctgccgatc caaataaacg tgtattggct atgccatctg
    55141 ttcgtcaatt tgcccgtgaa aaagatgtag atatctcaca agtaactgca actggaaaag
    55201 gtggcagagt aacaaaagag gacatcgaaa acttcttggc aggtggtcca agcagtgcac
    55261 cagcgaaatc agaagcgcca gaagcggcag caccgaaaga agcagctcct gcagcagaaa
    55321 gcaaaccagc tgcaccagca aaaccattca agtccaactt aggagacttg gaagaacgtg
    55381 tagcaatgac gccaacacgt aaagctatcg ctaaagcaat ggtcaacagt aagcatacag
    55441 ctccacacgt gacattgcat gatgaagtag aagtgtctaa actatgggat aatcggaaac
    55501 gatttaaaga agttgctgct gcaaatggta cgaaacttac tttcttgcca tatgtcgtga
    55561 aagctttaac agcgactgtt aagaaatacc cagtattgaa tgcatctatc gacgatgcaa
    55621 accaagaaat cgtttataaa cattactaca atatcggtat tgcaactgat acggatcacg
    55681 gactatatgt accaaatgtg aaagatgcag accgcaaagg aatgtttgct attgcagacg
    55741 aaatcaatga gaaagcaaaa ttagctcatg acggcaaact atctgcagaa gatatgcgca
    55801 atggaacaat tacgatcagc aatatcggat ctgtaggtgg cggttggttt acaccagtca
    55861 tcaactatcc agaagtagct attttaggtg taggaacgat tgcacaacaa ccaatcgtaa
    55921 atgctgaagg cgaaatcgtt gtcggtcgtg tgatgaaact gtcattaagt ttcgatcacc
    55981 gtatcgtaga tggagcaact gcgcaacaag caatgaataa tatcaaacgt cttttagctg
    56041 atccagagct attaatgatg gaaggatgat aaacaaatgg tagttggaga ttttgctgta
    56101 gaattagata cagttgtaat tggtgcggga cctggtggct atgtagctgc catccgcgct
    56161 gctgaaatgg gacaaaaagt agcaatcatt gaaagagagt atattggcgg tgtttgtttg
    56221 aatgtcggct gtattccttc aaaagcactg atagctgcag gacaccatta tcaagagtca
    56281 ctagattctg aaatgtttgg agtaactagt gaaaacgtca aactagattt tgcaaaaaca
    56341 caagaatgga aagaaaacaa agttgtccat acgttgactt ctggtgttgg tttcctatta
    56401 aaaaaacata aggttgaaac aatcgaagga gaagcgttct tcgtagatga tcacacacta
    56461 cgcgtcattc atccagattc agctcaaact tattcgttca ataacgcaat catcgcaaca
    56521 ggttcccgtc caatcgagat tccaggattt aaattcggag gacgtgtgtt agattctact
    56581 ggcggattag cattgaaaga agtacctaag aaatttgtga tcatcggtgg cggtgtgatt
    56641 ggtgccgaat tgggcggagc gtacgcaaac ttaggagcag aagtaacgat tcttgaaggc
    56701 tcaccacaaa ttttaccaac ttacgaaaaa gatctagtaa aattagtaga agatgatttc
    56761 aagaaaaaag gcgtaacagt cgtaacgaat gcaatggcga aagaagcagt cgataacggt
    56821 gacagcgtga cagtgaaata tgcagtggac gggaaagaag aatccgttac tgctgattat
    56881 gtgatggtca ctgtaggtcg tcgtccgaat acagatgata tgggcttaga acaagcgggt
    56941 gtcgaagtag gagaacgagg attgatcacg gtggataaac aaggacgtac gaacgtacct
    57001 aacatctatg ccatcggtga tatcgttcca ggggcggcat tagcacacaa agccagttat
    57061 gaagcaaaaa tcgctgctga agcaatctct ggcaaaaaag tagctgtaga ttataaagca
    57121 atgccggcag tagccttcac tgatcctgaa ttggcttctg taggtatgac gatcaaagaa
    57181 gcaaaagatg ctggtatcga agcaaaagca tataaattcc cattttcagg gaacggtcgg
    57241 gcattatcgc ttggtaaaac agaaggattc atccgtctag ttacgacgat cgaagataac
    57301 gtgcttattg gcgcgcaaat cggtggagtc ggcgcaagtg atatggtctc tgaattagct
    57361 ttagcaatcg aatcaggaat gaatgctgaa gatatcgcct tgacgattca tcctcatcca
    57421 tctcttggcg aaatcgtcat ggatgcttcg gaattagcat taggtttacc aatccatatt
    57481 tgatttgaat aatacaggcg aaacgcaact gaaaaatcag ttgcgttttg ttttttagaa
    57541 ttatcaataa tattattatg taaacttaaa aatatgacaa cttcttggtt tattaccact
    57601 tcctatgcta cactgaagag gaatatgaaa taggagagtt gaagatgcaa gaatatcagt
    57661 atccacttga tttagattgg acaacagacg aaatggtcat tgtaatgaag atgtgggaag
    57721 atctggaacg tgcgaatgaa aaagggataa acaatgaagc ttttttgaag acttatcagc
    57781 agtttaaaac tgttgtcaaa tccattggtg aggaaaaacg attgggacgg gaatttgaaa
    57841 aagcttccgg ttattcttta tatcgtacag tgcagcaagc aaaaaaaaat ccaaacaaaa
    57901 ctttgagaat gaacgggtga gataaatgga acagatgatt gatcatatca agtcctggct
    57961 tgaagaagct ggtgagaaaa tcaaatcttc tcaacaaaca ttaacaatct cgcaaaaatc
    58021 aaatcgaacg gatctagtaa caaatgtcga tcgaaacatc cagaattttc taatcgaaaa
    58081 aatccattcc tttgatccag aggcgaaaat attggcagaa gaagaagggt gtaatcaatt
    58141 atcggatctc gatggaagag tctttatcat cgatcctatt gatggcacct tgaattttgt
    58201 gattgaaggg gaaaattttt gtattatgct cgctgtttat gaatccggcg ttggaaagct
    58261 tggtttcatt tatgacgtga tgagaaatga acttttttgg ggtggaaaag gaataggcgt
    58321 gtataaaaat gatgagccat tgcctagacc agcaaataaa tccttatcgg aaggcttact
    58381 tggtgtgaat agttatcttt tcggtcataa taaatatgga atccgagaaa ttgcggaaag
    58441 cagcatgggg acacgtatgt acggatgcgc tggtcttgaa ctagtggcaa tcttgaaagg
    58501 aaaccacatt gcttatattt caaaccttag cccttgggat tatgcagcgg gaaatgtctt
    58561 attggaagag tttggtatgg taacaagcgg tctttttggt actcctttga catttgaaaa
    58621 aagggaatac tatttagcag ggacttcttg tgcatatgca gaaatcgcag accttttgaa
    58681 aaaagaaggc tgaaaaaaag gtagaaatca ttcacaaaaa tgataaaaac gagcaaaaga
    58741 ttaattttct cgaaaaaatg aaaacatttt actatatttc atgaaaaaag tctgctataa
    58801 ttagcagtcg agtaaaattt gccctgtcat aaagaaccaa taaaaaagga gttagttaca
    58861 ttgaattata gaaacgatat ccgtaacgtc gcaattattg cccacgttga ccacggaaaa
    58921 acaacattag ttgatgaact attaaaacaa tcagatacat tagacgcaca tacgcaattg
    58981 caagaacgtg cgatggactc aaatgcgcta gaaaaagaac gtggtatcac gattttagcc
    59041 aaaaacacag ctgtagacta taaaggtatt cgcgtaaaca tcatggatac tccaggacac
    59101 gcggacttcg gtggcgaagt agaacggatc atgaaaatgg ttgacggcgt tgtgttggtc
    59161 gtagatgcgt atgaaggaac aatgcctcaa acacgttttg tattgaaaaa agcactggaa
    59221 caacatatca caccaatcgt tgtcgtaaac aagattgaca aaccttctgc tcgtcctgag
    59281 catgtcgtag atgaagttct tgaactattc atcgaattag gagcagatga tgatcagtta
    59341 gactttcctg tgatttatgc atctgcacta aatggtacgt caagcttgtc agatgatcca
    59401 gcagatcaag aaccaaccat ggcacctatt tttgatacaa ttattgaaaa aatccctgct
    59461 cctgtcgata acagcgacga accattacaa ttccaagttt cattacttga ctacaacgat
    59521 tatgtaggtc gtatcggaat cggacgtgta tttagaggaa caatcaaagt aggagaccaa
    59581 gtagcattaa ttaaattaga cggaacagtt aagaaattcc gtgtaacgaa attatttggt
    59641 ttctttggac taaaacgtct agagattcaa gaagcaaaag ctggagactt gattgctgtc
    59701 tcaggtatgg aagatatctt tgtcggtgaa acagttactc ctgtggatca tcaagatgcg
    59761 ttacctatcc ttcacattga cgaaccaaca ttgcaaatga ctttcttagt taataattca
    59821 ccatttgccg gtcgagaagg taaattcgta accgctcgta agattgaaga acgtttgatg
    59881 gcagaacttc aaacagatgt atccttacga gttgaaccaa caaactctcc agatgcatgg
    59941 acagtttctg gtcgtggaga attgcatttg tctatcttga ttgaaaacat gcgccgtgag
    60001 ggatacgaat tgcaagtatc tcgtccagaa gttattgaaa aagaaatcga cggtgtaaaa
    60061 tgcgaaccgt ttgaacgcgt gcaaatcgat acaccagaag aatatatggg tagtgttatc
    60121 gagtccttga gcttacgtaa aggtgaaatg caagatatgg tccatacagg aaacggacaa
    60181 atccgtttga cattcttaac acctgcccgc ggtttgattg gttattcaac tgaattcctt
    60241 tcaatgacac gtggttacgg aatcatgaac catacttttg accaatatct gccaatgctt
    60301 cctggtcaaa ttggcggacg tcaccaaggg gcgcttgttt cgatcgatac aggaaaagca
    60361 acgacttatt ctatcatgag tatcgaagaa cgcggtacag tcttcgtaga accaggtaca
    60421 gaagtatatg aaggaatgat tatcggggaa aacagccgtg ataatgattt gactgtcaac
    60481 atcacgaaag caaaacaaat gacaaacgta cggtctgcta ctaaagacca aacatctgtc
    60541 atcaaaaaac caaaacaatt gacgttggaa gaatctttgg aattcttgaa tgatgatgaa
    60601 tattgcgaag taacaccaga aagcattcgc ttgagaaaac aaattttaga gaaaaatgct
    60661 cgtgaaaaag catctaaaaa gaaaaaataa tctgtaaaag gatgaagaga gaaaccagct
    60721 tgttataaaa aatagctggt ttcttttttt gtccaactct tttctgtgga gaagtcatct
    60781 ttgtcaatgg acataaattc agaaaatacg ccgaaagacg tttaaaagac ttttaaaaaa
    60841 cttatttcta gagagttttt gtttcataat aagataatgt ttcacgaaag gagatcaact
    60901 tgtccttcga agaaaatcga agtaaaatgg caagagaaag gagcgggaag atgaacgact
    60961 tattaaaaca atactttggc tatgatgagt ttagacctgg tcaaaaagaa attatccaga
    61021 aagtcattga tcaggaaaat gtattaggaa tcatgcctac cggaagtggg aaatcaatct
    61081 gttaccagct tccagcttta ctattagatg ggcttactgt ggttgtgtcc cctttaatct
    61141 ctttgatgaa ggatcaggtg gacgcggcga atcaattagg tatacccgcc acttttatca
    61201 atagctcgtt agatggttac gaaacagcta gacgcttcca agaaatcgat agacagcagt
    61261 accgtttact ttatatcgct cctgaacgtt ttatcatgcc ggattttatc caagcaatga
    61321 agcgatggaa cgtccgtatg atcgctattg acgaggcaca ttgtatctct cagtgggggc
    61381 atgatttccg cccaagttat ttacagatgg cgaaccagct agatcaactg ccaaatcgtc
    61441 ctgtaattgt tgctttgaca gctacagcga ctgtgcaagt agctgctgac ataaaaagac
    61501 ttttaaaaat tccagaaaac aaccatattc agactggttt tgaacgagaa aatctacgat
    61561 ttcaagtaat taaagatcaa aaaaaagaac aatatctaat cgaatattta aagatcaaca
    61621 aaaatcaatc tggtatcatt tatgcagcaa cgagaaaaga agtagaccgt ctctatcatt
    61681 tgcttaaaaa attcgatttt tccgtgggta gatatcatgg tggtctaaat gagaatgagc
    61741 gaacagaaat gcaagaagcc tttttatacg atcgcttgca gctgattgta gcgacaaatg
    61801 catttggtat gggtagaaat aaaagcaatg tccgttttgt tatccattat caaattcctg
    61861 gctctctaga agcatactat caggaagctg gtcgggcggg aagagatggt ctttccagtg
    61921 aagccatcct gcttttctct cctcaagata tccaagtcca aaagtttttt atccagcagt
    61981 cccaaagaga agaagggcaa aagcaaaaag aatatgaaaa attaaaagcg atgacagaat
    62041 acgtgtatat tgagtcctgt cttcagcaat acatcctaaa ctattttggc gagacaagca
    62101 gtccgtgcaa ccgttgtggt aactgtttag atgacagaga aatagtagaa gtaacgacag
    62161 aagcacagat ggttctttct tgcttaaaac gtatgggtga gaactatggt aaacaaatgc
    62221 tgatgaaagt cttagcagga tcgaaagaac aaaagctgca agctttaggt tttggacatt
    62281 tatctaccta tggactgatg aaaaaccaat cgcaaaaaga aacgatgcag ttaattgaat
    62341 atttgatatc gaatggctat cttctgacca tcaatggtga gtatcctgtt ttgaaagtaa
    62401 cagaaagagg gatacaagta ttgaaaggac aagaatctgt ttatcgaaag gaacccaaga
    62461 aagtccagca gctatcggat gaagaaaccg atacactatt tgaagtgctg cgggaactgc
    62521 gaacggatct agcatcagaa gcaggcgttc ccccgtatgt cgtattttca gattccacat
    62581 tgaaagaaat gagccgaata cgtccatcaa gcagattgga gatgcttcag ataaaaggag
    62641 ttggccaaag caagcttgat aaatatggcg aagccttttt atctcggata aaaaatgcgg
    62701 actctaacgt tctggataag tagaaagaac gaatacgtaa aaatgaataa aaacaactgg
    62761 ttaaatctgt tttttttgct ccttatgaaa atcaaatatg ttataattaa ggaattagaa
    62821 tgggaggtaa gcacagatgg attctttgtc gaaaaaactt gcgatccaag tattaaatga
    62881 tgaagcagaa cggatcaaac gattaatccg aaatcaaaac aacagtctct gtatctcaca
    62941 atgcaaagcc ttcgaagaag tggtagatac acagatgtac ggcttttccc ggcaagtcgg
    63001 ttttgctgtc cgtataggag taatcggaaa gaacgagggc cagctgatgt taagtgagct
    63061 agaacgagaa ttgaatcagt tatatagtga ggtttaccaa gaaatttatg ataaaaaaga
    63121 agttggcaag gaggaataga cttgcctaag aaagtgaaaa aaaggcatct attagactat
    63181 agcatcttga ttccctattt aattttatgt gtattgggat tgatcatggt atatagttct
    63241 acgtcgtatc tattattaga aaacggacaa aatccgtccg catcagtcat taaccagagt
    63301 attttttggg tgcttagctt gattgctatc gcactacttt ataaaatgaa aacagatgtt
    63361 ttgaaaaacc agcgtttgat catggcagcc atcgcagttt tgacgatttt gctgctgatt
    63421 gttgtgtttt ttggtaagga gatcaatggg gcgaaaggtt ggctgcaaat tgcaggattc
    63481 tcgatccaac ctgccgaata cctaaaaatc atttctatct ggtacctgtc tctgacttta
    63541 tctaaaagac aaaacagtgt acaaaaagat tttcttggga ctgtgaaacg tccacttgca
    63601 atggttatcg gacttactgc attagtcgct attcttcccg attttggtaa tgcggcagtt
    63661 atctttttga ttattttggt tctgctttta gccagcggag tcaattatgt gtatactttg
    63721 attgtaggag taggaggctt ttgtctaagt acttttacga tctggctgat caatatcaca
    63781 aacggaaaga tcttacccgg acgtttacag tatatctata atcgatttgc tatttaccaa
    63841 aatcctttct cagacgaatt aaataaaggg catcaactag tcaacggcta ctatgccatg
    63901 ttcaacggag gactatttgg caggggatta ggtaacagta tccagaaaaa aggattttta
    63961 caagaagcac aaaccgattt tatttatgca atcgtagtgg aagaactggg agtgattatg
    64021 gggattttga tattagcgtt gctattcttt atgattgtgc gcattgtcct tgtaggtatc
    64081 cgttcaaaag atccgttcaa ttcgcttttg tgcattggga tcggcgcaat gtttttgatc
    64141 caagtatttg tcaatcttgg aggaattact ggcgttattc ctttgacagg gatcacgttc
    64201 ccatttttaa gtcaaggagg ctccagtttg ctgatgcttt cgatttgtgt cggctttgtc
    64261 ctcaacatca gtgcggatga aaaacgcaag agcttaggtt tataataaaa aaagatgtag
    64321 gagtggttcg atgaaaaaag ttttagttgc taacaggggt gaaatcgctg tacgtgtatt
    64381 tcgtgcttgt acagaattag gaattaaaac tgttggaatc tatgcagaag aagatgaata
    64441 ttccgtacac cgtttcaaag cggatgaagc atatttagta ggacaaggaa aaaaaccgat
    64501 tgatgcgtat ctagatattg aagggatcat ttctatcgcg aaagaatgcg gagctgacgc
    64561 tattcatccg ggttacggtc ttttgtcgga aaacttgaat tttgcgcaac ggtgcgaaga
    64621 agaaggcatc atttttgttg gacccaaact gcatcattta gatatttttg gagataaaat
    64681 caaagcaaaa gctgcagcta tcgaagcggg gattgcttcg attccaggca cagatggacc
    64741 aatcgcttct atagacgatg ccttggagtt tgcgaaacaa tacggttatc cgattatgat
    64801 caaggcagct ctaggcggcg gcggacgcgg catgcgtgta gctcacgatg aaaagagtgc
    64861 aagagagggc tacgaacgtg cgaaaagcga agcaaaagca gcctttggta gtgatgaagt
    64921 gtatgttgaa aaatacatcg ctaatcctaa gcatatcgaa gtacagattc tcggggatac
    64981 gcatggaaac gtcatccatc tttttgaaag agattgttct gttcagcgcc gtcaccaaaa
    65041 agtagtagaa gtagcgcctt gtgtctctat gaatgaacag caacgtcaaa aaatctgcca
    65101 ggcagctgtc caattgatga aatatgtcgg gtatgtcaac gcaggtacag tagaatttct
    65161 tgttgaagga gatgattttt actttatcga agtcaaccct cgcgtccaag tggaacatac
    65221 gatcacagaa atgattacag atattgatat cgtaacaacg caactgttga ttgctcaagg
    65281 tttggatctg cataaagaaa tcggattgcc tcagcaagaa ggaattaaat taaatggttc
    65341 agccattcaa tgccgaatca ctacagaaga cccgttgaat aactttttac cagacacagg
    65401 gaaaatcgat acgtatcgtt cacctggtgg ttttggcgta cgtctggatg tcggaaatgc
    65461 ttacgcgggc tatgtagtga caccgtattt tgattcattg ctagtaaaag tatgtacgca
    65521 tggtgctacc tttgaaacag ccattcagaa aatggaacgt tgcttgaaag aatttagaat
    65581 ccgtggagtg aaaacaaaca ttccatttat gctcaatgtc atcacacatc ctgaattcca
    65641 atcaggaaat gcaaaaacaa ccttcattga tagtacagca acattatttg aatttcctcg
    65701 actacgagac cgcggaaaca aaacgatgaa atatatcggt gaaattactg tgaatggttt
    65761 tccaggtatc gaaagtggcg aaaaaccatt ttatgaagaa ccacgtatgc ctaaagatct
    65821 aatcacaaga actgattacg taacggctaa gaatgtatta gatgcgaagg gtgccgatgc
    65881 tttggtcgaa tggatcaaag gacaggaaaa tttgttgttg acggatacga catttagaga
    65941 cgcccatcaa agtctgctag caactcgtgt tcggacaaag gatttcaagc agattgcacg
    66001 tttgactgga gaaggtcttc ctgaactctt ttcaagtgag atgtgggggg gagcaacatt
    66061 tgatgtggct taccgctttt tgaatgaaga tccttggcaa cggttgagaa aaattcgttc
    66121 tttaatgcct aatacgttgc tgcaaatgct tttcagaggt tcaaatgccg ttgggtattc
    66181 taattatcct gacaatgtat tggtggaatt tgtcaaagaa gcagcagcgc aaggaatcga
    66241 tgtatttcga atctttgata gtttgaactg gactccacaa atggaaaaaa gtatccaagc
    66301 tgtacgggat actggtaaaa tcgcagaggc agctatttgc tatactggcg atatcaacga
    66361 tccaagtcgg gcaaaataca atgttcagta ttataaagac atggcaaagg aactagaaca
    66421 actgggtgcg catatcattg caatcaaaga tatggctggg ctgcttaaac cgcaggcagc
    66481 ttatcgtttg attagtgaat tgaaagaaac gacagatctg ccaatccatc tgcatactca
    66541 tgataccagc gggaatggaa tcatcactta ttctgctgct tcaaaagcag gagtagacat
    66601 cgttgacgtg gcaatgagtg caatgagtgg gaatactagt cagcctagca tgagcagctt
    66661 gtattatgca ctggtcaatg gtccacggct gccagaaatc acgattgaaa atgcacagaa
    66721 attaaaccat tattgggaag atgtgcgcat gtattacaaa ccgtttgaaa acggcttgaa
    66781 tgctcctgaa acagaagtat atatgcatga aatgccagga ggacagtatt cgaatctaca
    66841 gcaacaggca aaagctgtcg gattaggtca tcgctgggat gaaatcaaac aaatgtatca
    66901 tactgtcaac ttgatgtttg gcgatatcgt taaagtaact ccatcatcta aagtagttgg
    66961 agatatggca ctatttatgg tccaaaatga tcttacagaa gaagatattt atgaaaaagg
    67021 cgaaacacta agtttccctg aatctgttgt gactttcttc caaggagaac tagggcaacc
    67081 cgttggcgga tttcctaaaa aattgcaaaa gattattctt aaaggcagac ctgcattgaa
    67141 tgaacgtcca ggtcttttgg ctgaatcagt cgacttcaac gaagtaaaaa aagaattggc
    67201 agaaaaaatt ggctatgaac caaaacaaga cgaagtatta agctatttga tgtatccgca
    67261 agtctttttg gactatcaaa aagcatataa tcaatttggc gatgttacat tactggacac
    67321 accaacattt ttccaaggta tacgtttggg tgaaacaatc aatgtacaaa tcgaacgcgg
    67381 aaaaacgctt atcattcgtt tagatgaaat cggagaaccc gatatcgaag ggaatcgcgt
    67441 actgttcttc aatttgaatg gacaaagacg tgaaatcact atcaaagata attcgatcat
    67501 cagtacggtc caaacccgat tgaaagctga accgacaaac cgagaacaaa ttggagcaac
    67561 gatgtctggt tctgttttgg atgtattagt gaaaaaaggc gataacgtta aaaaaggtga
    67621 tacgttgatg attactgaag cgatgaaaat ggaaacggcc atcgaagcac gttttgacgg
    67681 agaagtcgca catgtatatg tgtcttcagg agacactatt tcgtctggtg accttttgat
    67741 tgaagtgact gagaaataat aagcgaaagg tggggaaaca tgaaaagact gggtttgttt
    67801 tggctgattc tgctattagt tattgtggca ttctacatgg aaccagtctt gtttccgcca
    67861 aaacttgaag tgaaggaaaa ctctgatcaa caaatatcaa accaaatgac aacgtggaaa
    67921 taccaggagc ttaaagcaac tggtttttct acttatatcg gaaaaccgat cgatcagctg
    67981 gaaaaggatt ttggccaagc ctatgatcga ttaactagcg gatttggttt tgaaacaaga
    68041 tattatgaaa ataaagctag tcatctcaca tttgaagcga acatccaaga cagcagagtc
    68101 acaactgtta aagtactgca aacagggcct gctgatatcg cgccgtttta tttagggatg
    68161 acgatgcaag atcttacgaa aatcactact atctatacta atttcacttt tgagtaccat
    68221 gatacagaag ttggaatcga actaatggaa gaggatatga attatcgtcc gctaattgct
    68281 tttgataacg acacttttgc tattttattt tttgatcaaa caacaaacgg cctattttca
    68341 gttgtgtatt tagataaaga tagtcttttg aaactattgc catatcaagt gtttggtgaa
    68401 ggccttccac attatcaagc agataaatcg gctgattggg aatcaatcaa tcgcgttaaa
    68461 gaacgaaaaa gtacgacttt attaaatatg cttagaagag aagacgaact tcccatatac
    68521 aatcaaacac ttgcctttca aaaccacagt cagctgctac tacatgattt tttgacaagg
    68581 cctgaggaaa tattgtcaga ggaacgtatg gctgattggc aaaaatcgct aggcagtgct
    68641 caaacgacag tgaaattctc actgacgaat gatgaattgg agaagttaat cagtaaacaa
    68701 aaattagaaa atactagtgg gctatttatt catccggcga ttgacgctac tttttcgttt
    68761 ttatattggt acagcgatcc ttacaaccat gaccgtttca tggacccggg aacggattct
    68821 gtaggcattg ctttttctaa agaaaatatg ttagtcttat tgcaagaaga aaacggagaa
    68881 agtagtgata gcagtgatcg ttaacgaaga gctgtttcaa ctggaggatc aatgcctcca
    68941 agtcgctgaa atgataaaaa agagtaaaac gatggcttct tatcttgaac ataaacagtc
    69001 aatggaagaa tctgcaaaag tttgccagtt gaaagaagcg ttcttgtcta agaaagaagc
    69061 atttgaaaat gtagcggcat atggtgagta tgcacctgat tatcgtgaaa aaaaacgagc
    69121 tgttcgaaaa gcaaaaagac agcttgatat ggatgagcat gttgcagctt tccgatatag
    69181 tgaaacacag ctgcaaagtc tgttggatca aattgtccaa gtacttgccg aagaagtttc
    69241 taatgaaatc aaagtagatg caggtagccc gttttttgaa acgaaaaaac actttggatg
    69301 cggaggtaat tgtcatgcaa ttagacaata gtgaatttga aataacaaaa cgacgcgggc
    69361 tgatcgtatg ggtctacagc ttaaaacaat taaagaatct gaaaaagttc ggcttgttgc
    69421 attatgtctc aagaagaatg aaatatgtcg tgctttactt aaatgaagag acattggaag
    69481 aaacagaaga acgaatccgt aaattacatt ttgttcgaaa cgtagaacgt tcttaccgac
    69541 cggatatcga aatgaatttt gccgaaaaaa taggaaacaa aacagtatta aaagacgaag
    69601 gtttcgaaat tgaagagcta aatacagaaa tccgattagc tgaacatctt taaaaatctc
    69661 ttatgagcag tttttaaata aaaaataact tggataacga tcgatttttg atcattgtcc
    69721 aagtattttt ttggtatact agtaccagta ccatttctaa ggagtgagta gatgcggata
    69781 atatcaggaa attatggcgg gcgccgttta aaaagtttag caggggcgaa caccagacca
    69841 actacagata aagtaaaaga atccatattc aatatgattg gaccatattt tgatggagag
    69901 acagtattgg atctgtttgc aggaagcggt ggtttagcta tcgaagcagt atctagaggc
    69961 tgcagtcatg cggtatgcgt agacaaaaat taccaagcgc taaaaatcat caaagaaaac
    70021 atcgaaatta cgaaagaacc agagaaattt accacaataa aacttgatgc ggacaaagca
    70081 atcgaacggc tagcagcgga gaaacaacaa ttcgactact tgtttcttga tccgccatat
    70141 gcaaaacaaa aaataatcga tcaaatccat aaaatggaag aactgggact tttttctaaa
    70201 accgcagtta tcgtatgcga aacggataaa acagtcgaat tgccagaaac tgtggctgga
    70261 ttccatcaaa taagaaaaca gatttatggc ataacggccg taactatcta tagaaaagag
    70321 ggaaatcaat gaaacgtgca ttattcccag gaagttttga tccttttaca aaaggtcact
    70381 tagatacggt ggaacgtgcg gctaaattat tcgatgaggt agtaattggt gtttttatca
    70441 atacttcaaa gaaaagtttg tttcccccag aagaaagaat gacattgatc acaaaagctg
    70501 tttctcatct tcctaatgta aaagtcatgc atcaagaaaa tcaattgacg gtagaaacag
    70561 caaaagagat tggtgcagat gcgttgatca gaggcatacg aagtatcaaa gactttgaat
    70621 atgaacgaga gattgctcag atgaatcatc atctatatga tgaattggaa actgtcttct
    70681 tattagcaaa accagaatat agtcacgtga gttccagtat tttaaaagaa gtactgcact
    70741 ttggcggaga tgtgagcagc tacttaccgc cagtgatcaa cgaagcttta gctggaaagc
    70801 gtgaatcaaa tgaaagctaa acaatggttg aaaacagtac tgattatcat atttggaatg
    70861 ttgatcattg gatttgtagt agttcccttg ccgtattatg tagaatcacc gggagccacg
    70921 atcgatctga aagaactaat tacggtcaat gataaggaag ataaaggttc tgggtctttc
    70981 tctcttacct ctgttggtat caggcaagct acaggtttct tagctttaaa agctaaaatg
    71041 accccttttg aagaattgat cagtgaagaa gaattgactg gtggggcgac aaatgaagaa
    71101 tataatcaaa tgcaacagta ttatatggat tcttcccaaa atgcagcaat cgaacaagcg
    71161 ttaaaacttg cagacaagcc ttataaaatg gaattcaaag gcgtatatgt catgagtgta
    71221 gagaaaacat cgaatttctt tggcaagctt tcagttggag atacagtaac aaaagtagac
    71281 gggaaaagct ttcaaagtac agaagcattt atggattatg taaaaagcca aaaagttgga
    71341 caaacaatcg aaatcagtta tttgcataat ggtgaagaaa aaacagcttc tggtgatctg
    71401 atcgagttac caacagataa aaaggcagga ataggtatca cgcttactga ccataccgag
    71461 atcgaatcag atacagatgt tcgtattaat tctggctcta tcggtgggcc atcagcggga
    71521 ttgatgttca ctttagaaat ctatgaacaa gtcactggta aaaacttgcg acatggtaag
    71581 caaattgcag gaactggaac gatcaacagt gaaggagaag ttggccgaat cggaggaatc
    71641 gataaaaaag tggcaagtgc ggataaagct ggcgtagaga ttttctttgc accagatgat
    71701 acgatttcag acgatgttaa gaaagaatat cctgaaataa aaaccaacta cgaagaagca
    71761 aaagctgccg ctaaaaaatt gaattcctca atgaaaatcg taccagtaaa aacagtacaa
    71821 gaagcgcttg actatctaga gaaaatgaaa tgaaactaaa taattaaaga ggggttgtga
    71881 cacgagttct gtcacaaccc ctctttttcg tcaaaaatct tcacgataaa aataaaaaca
    71941 aaagaaaaaa ttgacgtaat tagatgttga agggacgatt ttgccagagc tcactgtttc
    72001 ttcaatttta aatgaaagga gtaatgaatg atttttactg gtcattcttt gaaaaaagaa
    72061 caatgataga aaaaatcagc aagaaaatac tagcttcacc caaattgatc atttggatgt
    72121 ctatgatagt tcttatcttt tgtatcgcaa gtggtttttt attatcaaat ttgctatttt
    72181 atagagaaac agaagagact gctgcaaaag aaatactttc ttcgtttagt tccagtggag
    72241 aagatccatc agctgaagga aacgatgtag aagaggatgc tcgtccaaag gtcatgtaca
    72301 ccgatatcaa aggaagtgtg aaggagcctg gtatctattc cttttcttca gaagaacggg
    72361 tctatgatgt actaaagcgt gcaggtggat tattagaaga agcggatagc gatcgaatca
    72421 acttttctgc gaagatagaa gatcagcaag tcctatatat ccctgctgta ggtgaagagc
    72481 tgccagaaca tcttgatcag ttggcatcct cggaaggaaa acagcctaca gcagattccg
    72541 agcctcccaa aataaatatc aatacagcca ctccatcaga acttcagcag attcctggga
    72601 tcggatcagt caaagcgcaa gaaatcattc gatttagaga agaaaacgga tccttccaga
    72661 aagtggaaga cctgcaggag atttctggta tcggtgaaaa gacagttgaa aaactaaaaa
    72721 acttcgttac aattaaatag aatgattcaa aatcgactgg cacgagcaat aaatggacgc
    72781 taatggatac taagaataat ccaattctaa gagcttggca ggacgaggag gtagtatttt
    72841 tggataggaa atagcttgat tgttcgcaaa gaaacattaa aaaaaccaat gctgaatgtc
    72901 tatctccaaa ataaaatatc tgggattcat attatgaata cggctgtcag cggcaataac
    72961 agtcaagctc tacgagaacg ctttgccaaa gatgtactta gctatacagc agataaagta
    73021 tttattctca ttgggacgaa tgatctagca gagcataaac aactttctaa agaaacgtac
    73081 caaaaaatct gcagtggatg atagttcagc tgaaaaaaga ctatagttct gatcatgctt
    73141 tctttatcac gccaccagca gtcgatgaga caaaacaaaa atatcggaat aacaagttga
    73201 tcaaagaata tatctctgtt ctcacagaag tagcaaaacg ccatgattgt gaagtatcga
    73261 tttttatacg gaatttcttg aacaaatgga ttcgaagaat ttttataatg ggctaatgga
    73321 tgacggactt catttcggca gtgaagggta ggatcttttg tcagacagga tgattcgtta
    73381 tatttaaaga atattttgtt taagcaatga gtacttttta atcaacttga aaaaacggag
    73441 gaatataaaa catgttagaa aaatcttcaa aagcatgcga tacgaataaa gaaaaagtta
    73501 ctgataagtc acataatgaa cgcattcctt gggaccagta ctttatggct caggcagtac
    73561 tgttatcttt acgtagtacg tgtacacgtt tagaagtagg agcgacactc gttcgagaaa
    73621 aaaggatcat tgctggcggc tataatggag cagtcagtgg agatgtccac tgcatagatg
    73681 aagggtgtta cgtcgtggat ggacactgct tgcgaacgat ccatgcagag atgaatgcac
    73741 tcctacagtg tgcaaaactt ggtatcccga cggaaggttc agaaatctat gtcacacatt
    73801 ttccatgttt ggcctgtaca aaggctttgt tgcaagctgg tgtgaaaggg atcaattatc
    73861 tccatgacta tcgaaatgat ccttatgccc aagcgttgat cgaacaatta ggtgtatctg
    73921 tacaccaagt tgctttagac tcacagcatt tttcaaaact tcaaaatgaa ttaacaggaa
    73981 aacatgtcta gcgttttaga aaggcatgtt cgaaatcggt tgatttttcc ggcaattacg
    74041 tcgatgatta tctgtttgtt gtattacact gacaattggg gttatcgttt gcttcttgcc
    74101 ggaatttttt tatggttttc gctaaaagaa ggacgtttta tcgcgtactt gtgtattttg
    74161 tgtagcataa cggtatccat ttcttatagg ctacaagagt attcattttt agaggaaaaa
    74221 acaacatctg cgcaaattac tgtatttaca gatacgattc gtgcaaatgg taattttttg
    74281 acaatggaag gaaggttatc agagaataaa caaaagctcc agctttctta tcaagtaaac
    74341 acagaagcag aattgaaaac atggcttaac ttccgaggaa agggaataga attgactgct
    74401 gaaggcgagt tcatctctcc agcaaaaaag cggaatcttt ataattttga ccaagaagct
    74461 tacttcagga accatagaat ttctggacgg ttccaaattc aaaagattga acagatcacc
    74521 atgcaaaatc actggcgaaa ctggcttcag agaaaaagag gatcttttat ctcctttgtc
    74581 caatctgaat ttccgcaaaa aacaagtgta tatattaatt ctttattatg gggctataaa
    74641 gatgcaggat tcagagaacc agaagaaatt tttagggaga gtggtttgct gcatctgttc
    74701 agtctatcgg gtctacacat ccaattttat ttagggtggc tgtattattt atttcgacgt
    74761 atcggatggc cactacacgt cagtattatt ccgttgagtc tactaactat ctgttatgtt
    74821 tctattgcag gaagttctat ttctgttttg cgtgctagtt tgctgttttt attgcgattg
    74881 ctagtcaaat tgctgaataa gcattattcc accatggact tatttgcagt tgtcttttgg
    74941 cttcttttac tatttgatcc tcgatttctt tttcatgcgg gtggacagct tagttttttc
    75001 atgagttttt tgtttatcct gatttctttt gatggagatt ggttgaaaaa aacggcctct
    75061 cacgtcctgt ttactatgat cacgatgccg ttgattgtat ggcattttta tgagtggcct
    75121 attttaggta gtctttttac attactgatt gcaccggtat tcaagtttct ttttcttcct
    75181 ggtgtgttat ttctcacact cttcaatcgc tggctgccgg aaactttact tttgttgata
    75241 gaagagggat taatcttatt tgagcgaata atcgattttt cttcagggtc gtctctcatt
    75301 ataggacgtt tgccccttgt gctatctggg atgtatattt tcggattact gatttgtatg
    75361 gataggttga aagaacaacc tgtgaaacac ttgttttatg ttggtctttt ttcttttatt
    75421 tttttgactt tgccattttt acgcttttct tcaacgatcg cttttatcga tgtcggtcaa
    75481 ggagacagta tctttttgca aagtcctttt cgaaaagaaa cgattttgat cgatactgga
    75541 ggtcagttac actttgaaag agaaaagtgg gcgcaaggta tgatacgtcc tcctgctgaa
    75601 agaaatatcg ttccatatct aaaaggtcag gggataagtg taatcgataa actcatcttg
    75661 acacacgacg atacggatca tgtgggagaa ttacccacgt tatctcagca ttttactatc
    75721 aaaaaaattt atatcggttg gggcgctgga cgaaatgagc cattacaaag gcatttatct
    75781 gaagctcaaa aaaatggtac tgagatcatt gaaatcaaac atggggacag gatcagcggt
    75841 tattatgatc tttatgtatt gactcctttt gaaaagggag agggaagaaa tgaagattcg
    75901 attggtctat ggatggaata taacaatagg cgctttttat ttttaggaga tttgaatcaa
    75961 gcaatggaaa aacaattgct tttgatttat cctaatctga aagccgatgt agtcaaatta
    76021 ggtcatcacg gtagccgtac gtcaagtaac acagattttc tttcccatat tgaagcaaaa
    76081 catgggatta tatcctgcgg cgtaaataat cgttatggtc acccgcacag cgaagtattg
    76141 gagacactag aagaaaatca gataaaaaca tggcgaacgg atcaacaagg aatgatcacc
    76201 tatcgctggc atccagtttt tcatcctcat gggctagtgg aaacaatgat agactagtaa
    76261 ttctcatctg ctcatggtag gataattttt gaaagtggtg agtaatttga gtatacaagc
    76321 agagttacaa aaaatacgta aagaaaaact tgcatcttgt tacttgattt taggaacaga
    76381 aaagtttctc caagatcaag ttcggacaga aattgtcaaa aaaatccaat tagagggcga
    76441 agatgactta aattttttaa gttttgacat ggaaaatgca agtttagatg aggtagtagc
    76501 tgaagcagag acgttgccgt ttttcggaga tcaacggtta gtattcgtag agaatcctta
    76561 ttttttaaca ggtgaaaaag taaacaatgg aatcgaacaa aatactgatt tattgacggc
    76621 ttatttgaaa gaaccattag aatcgactgt attagtattc tttgcgccat atgaaaagtt
    76681 ggatgaacgg aaaaaagtaa cgaaacaatt gaaaaaaaca gcaattatca tcaatgtcca
    76741 acagttgaat gaaaaagaag tacgtcaata tctgatgaat accttagaga attcctcaat
    76801 caaaatggaa cgaagtgcaa ttgatttatt cttgaggttg accgacttag atttatccaa
    76861 aatgatgaga gagttacaga aattggtcct ttatggacaa aatcaacagc aaatcacggt
    76921 aagagaagta gaagaattag ttcctaaaac gttagaacat aatatttttg acatgaccca
    76981 atatatttta aaagggaaga cggaacaagc tttgcgttta tacgaagatt tagttatgca
    77041 aggggaagaa acaatcaaaa ttaatgcgat tttgctttct caattacgtt tatttttaca
    77101 gacaaaattt cttgtaaaga ttggttatca gcaggcaaat attgctgaaa cattgaaaat
    77161 ccatccatat cgtgtaaaac ttgccatgca ggaagtaaaa aaattcgatg aacatttgct
    77221 ggtacagttg tttgatcaat tagttgagat ggattatcaa atcaaaacgg gacaaatcga
    77281 aaaagaatta agttttcaac tattcgtttt gcgcacaggg cagttgttaa gaaatcgata
    77341 agaagaaaga cgagggcaaa gcatgcggga aggtcgtttg tttttgtcct ttttttgaca
    77401 aataaaaaaa tcggccgaag ccgattcttt tatttagcga tttttttgct taaacgagat
    77461 ttgtcgcggt tagctttgtt tttgtggatt agaccttttg attcagccat atcaatagct
    77521 ttaacagctt ctttatataa cgcatctacg ttgtcagcac ctgaagctac agcatcttca
    77581 aattttttga ttgcagtacg catagcgctt gtttgagatg aatttttcac attagcgttt
    77641 tcgcttgtac gaacacgttt gattgcagat tcaatgtttg gcattagttt cacctccgat
    77701 aacttaagtt cttacgcgtg ttaccgcata attcaacatt cattattata cctaaaggca
    77761 gcgtgctttg caatatgaac atgacaagtt tttttcctta acagtctttt attaggattt
    77821 tttttcagta aaaacggata gtacaagctg aaaaaaatca aaaagacgct attgtgggag
    77881 gcaatagcgt caaaccaaac tagattttta tttatctatt taaacaaagt ttgaatggga
    77941 atgtttggta ctaagttatt atataacaaa gagaaccgtt tgcaaagttt tttttgaaaa
    78001 gggatacgat tccctgttgt tctttgtttt tctattaaga aactgcagtt attttataac
    78061 cagtatcctt tgatcagtaa aggctattct ggtgtaccga ttattttaat gtattcatcg
    78121 atatttttta tcaacatttt ttttatgacc aactggttcc gacggttcca tttgccactt
    78181 acttccagca catatttatt taggggcaaa cgtaagatat attttgccaa atagcgatct
    78241 ttaagcaggc cattgatcac acggtcctca agctgcaagt tgatcccagt cagcatcatt
    78301 ggctgttctt gtaaaacgta cgtatcaatt aaaagacctt caaaagtttc cacaagcgtc
    78361 ttcctttctt ttcaaagtaa cctgaaaaca ggcactaatt cttccatttt gatattcgtt
    78421 gaagtggatg cgatcattct ttcttttgtc cactgtaatc tagtataaca aaaaagagca
    78481 gaagagccaa aaagaaaaaa gagcatcgaa ttctatagga agtctcattg gcacggccta
    78541 aattattaca aaacattgat taaaaaaagc ccctgcatcg caggagcatc ccctatatcg
    78601 ttttaatagg tcaatcaaaa agcagtatca aacacatttt gtatcaaatc aggaaataat
    78661 agataagcta agcccagaat caaaagtacc gctagaagaa accagccgat tgttcctatg
    78721 aaatacttta atttttcgaa cattgtatca cctcgttgtc agtatatcac ggatcagtaa
    78781 attgggggtg ttaagaatct cctaaaatag acaaaatttg ttctattttc ctaaagcaaa
    78841 tacttgtaag atacagtaag tgataccaga agcaatgacc ggtccggcgg cgattcctct
    78901 taagaagaca acacctaaaa tcgtgccgaa aacaagtgca acagtgattt gtggatcaga
    78961 agcaatcaat cctacaccct tggaagataa gacagccact agcccaccgc aaaaaacagc
    79021 tacccagcca ataggggatt taaaggcttc taatagatca cgtagaccga tttctcctgt
    79081 tgcgataggg attagaatag ccgctgtgat gatcgtcacc ccaatattga ttcctttgcc
    79141 ttgaagccaa gggaaaaagg aacgggaggc tggtatgagc ttcataatca aaacaaaagc
    79201 tgccgctatc atcagacttt gatttttagc taaaattgct acaagtaaaa taattcctaa
    79261 aaaaagccaa ctttccatga aatatattcc tcactttctt cgaaacaatc ataacatgtt
    79321 tttagaaagt tacaaaagta ggaattcatc cttcaagacc tattcataag ctgttttttt
    79381 cataaaataa acaaaatcat aaaaaaacac tttgcttatt tgacagaaga cagccgcgct
    79441 ttgtatagtg gacaagactt acattttttt gaagaatcag aaagatcagg taaaggtctt
    79501 agtaaacgca agccattcag aataaccaat attgtgcttc cttcgtgtcc tacaactcca
    79561 agaggtagat ttaaaaattg caggaagtta gaagcaatca acaagagaat aacaagaatc
    79621 gaaaaaataa tattttgttt gatgatccgc cgcattttta aagatagccg atgactgtag
    79681 acaaatttat ttaagtcgct tttcattaag acgatgtctg cgatatccat agcggcatct
    79741 gtcccttgcc ccatagcgac acctaaagaa gcggctgcta aagcaggcgc atcattgact
    79801 ccatcaccaa ccatcgcatt tacttggtaa agttcattct cttttttgac tagttgtgtt
    79861 ttttcttccg gagtacagct tgcatagtaa tgttcaatcc ctacttgttc agcaatggcc
    79921 tttgctgtgc cagaatggtc gccggttatc atacttgtat ggatgttttg ggatttaaag
    79981 taggaaatta cttgttgggt atttgctttt ggaatatcta gcagacctaa aacagcaatt
    80041 aactgctgat ctttagaaag ataaatcacg gttttgcctt gattttccaa acgttcgatc
    80101 atttccgcaa tctctttgct gattatcatc gtctcaggat catatgcgtg cttgccaact
    80161 ttccattgcg cacctaaata ggtagtttgt aatccaaaac cagtaatttc ttctattggt
    80221 aagtattgga tttcttcagg tattgtgcaa tcgaaatatt gcaaaatcgc atgagcaagt
    80281 ggatgcgtcg ttttttgttc catagcaaca agaagttgtt gtgccaaatc cttttcatca
    80341 aagaaaaagc tgtcagttac aactggtttt cctttagtga gcgttcctgt tttatcaaag
    80401 gcaatcgctt ttaattcaga aagcttttct aaatggatac cgcctttgat taaaatccca
    80461 ttttttgcag aatttgaaag agcagctaga gaagctggtg tagcagatgc gacaagcgca
    80521 caaggagaag ccacaactaa taataccatt cctcgataaa agctttcatc ccaactccaa
    80581 cctaggaaaa agtgggggag aaggatcatt agaggaacag caagcaaaat caattttaca
    80641 taattatttt cgattcgttc gataaatgaa gctgtttgag ttggcgtatt ctgcgcttct
    80701 tctactaatt ggataatctt agcaaagaca gtttcggaac tcgtttttgt tactcgaatc
    80761 gtgatgggat ttccttgatt cagcgttcct gcatacatct catcgcctaa atatttttct
    80821 acaggcacag attcaccgct taatgcagac tcatcgatcg ttgcctgtgt gctttctaaa
    80881 aagccatcta tcggaacagc tgctccttta gcgacaaata ccaagttatc cacctttagt
    80941 tgagaaacat ctacttcttg catttgtcca ttttctttta ataattgggc tttttgtggt
    81001 tgaagattca tcaaagcagt aatttctttt tgacttttat tagttgtgta ttcctctaat
    81061 gcaccgctta aacaaaagat gaatgtcaac attgctcctt caaagtaatt accgatcaaa
    81121 caggcaccaa tagcagctaa agccatcaat aaatccacat tcagtgtccg atcattccac
    81181 aattctttca agccttccga tgtttgttta tatccaccga tgataatggc actgatataa
    81241 aaaagtgggg tgatggtaag agagaatcgg tcgaagataa aaccgaagat cataaataaa
    81301 aggcagccga ttgttgctgc aaaagctttt ttctgattag tcatcgttat tagacctcct
    81361 tgtcaaaaca aggatagcat aataaaaatg taattgataa taataacagc taaatgagaa
    81421 cgataatggt tatcatttgg tgattaagct tgatgttgtt tttattattt ataatgatta
    81481 ttattaaaga aaataaaaaa ccagaacatt tctcaaataa gagaagtgtt ctggtttttt
    81541 ctacattgca ataaaccaat aaccaatcaa aatgatacca aggataatac gataccagcc
    81601 aaaagcggta aagtcgtttt tcttcaaata gcttagtaag aatttgatag ctaagacgga
    81661 aaccacaaaa gatacgaatg ttcctacaag aagaacaaca gtttcttcca ttttgaatga
    81721 attcccttca gctaaatatt tgacgatctt caagccgctt gcgccaaaca tgacaggaat
    81781 ccctaagaaa aatgaaaact ctgtagcgac aaaacgcgaa gcaccaatca agatagatcc
    81841 taggatcgtt gcgccagaac gggatgttcc gggaacaagt gccaagactt ggaataaccc
    81901 aacaagaaga gctgcttggt acgtaaagtc attcagagaa gtccaacgag gtgttttgtt
    81961 tttgttgcgt ttttcgacaa taataaaggc aataccgtaa acgatcaaaa caatggcaac
    82021 tggtaagaac ttgtggaaat ttgcttctaa ccaatcatcc aaaggcaaac caatgatgat
    82081 ggctggtatg caagcaacga tcactttaaa ccaaagtgtc cacgtatctt ttttttctac
    82141 cgttgattta cttggagaaa atgggtttaa cttgtgaaaa taaagaacga cgacagccaa
    82201 gatcgcccct aattggataa cgacattgaa catcgacata aattgtgaac tggcatccag
    82261 tttgatgaat tcatctgcta ggatcaaatg accagtacta ctgatgggca gccattccgt
    82321 tattccttca ataataccga gaatcactgc tttgataata tttgcaaaaa acataaattc
    82381 cttccttccc aattaagata catcttatag tataccgtta ttttttgaga aacccaatct
    82441 gttttttaat attaagaaaa acttgagaaa taaagcagat aagtacacga agagaaaaaa
    82501 gaagacaaag ccctcgttca gactttgcct tttatgattc tctggtaaaa attaaaatat
    82561 ccccattata gaaacgagtc gcgactatgt gttttcccgt tatcgatata agacgtatca
    82621 ttgatgccgt ggatagaaaa tcgaccgttt gcataagtga cctttgttac gctgccattt
    82681 aaaagcccag cacgaacagg ctgtttagga tcgatcagat taagcaaaaa ggcgatcgtc
    82741 aaaccatgag atacgactaa aacatttcca ccaccatttt tttcgcagtg atgggcgata
    82801 tcttcaaatc ctgtccatac acggtctcgc aatgtttcat aagtttccgc ccacccagcg
    82861 gtatctaagt tgtatacagc attagcaatt tgttcaaaag aaacttctgt ggtaaacatt
    82921 tcatcatatg ttttaaaatt caatacacga gggatcacac cccacatttc catgtcatat
    82981 ccaccttcaa gagacccgaa acaccattct ctaatccttt tttcaataaa ataaggaatt
    83041 tcttttccct tagaatgttc tcctagaata atacgggcag tttcgattgc acgaccactg
    83101 tcactagaat aagcaaatga aaagtcgaca ttttttaacc cgcgacctaa ataatgaatg
    83161 ccttcttgtc cttgctttgt gaggggtgta tcacaccagc cttgtactcg ttcaattgta
    83221 ttgaacatcg tttttccgtg tcgtacgata taaagtgtag tttctgtcat tttattctcc
    83281 tcctaagtcg ttttaacgat tgaaaaaagg atttgtcctt ttttcctgtt caatcgtcgt
    83341 tgcatcgcca tgtcctggat agactgcaaa ttcatcaggt aatacaaaca gctgggtccg
    83401 aatactatga agtaattgtt ctaaattccc tgtatacaga tcggttctac cgatacttcc
    83461 tctaaacagg gcgtcgccag aaacgacaaa atcatcaaaa ataaagctga cgcttcctat
    83521 agaatgccct ggggtaggga cgacgcgaaa agacatgttt cctaaagtat aagttttcat
    83581 ttcaaattca tattctgcag gcgagacaat aacatcagca atatcatcat gtctaccgag
    83641 tccagaaaga ttcaaaatcg gatcacctag ccatttttgc tctagtgggc tgacataaac
    83701 tgggatttga taatacgcgc gtaaaggttc cactgcaccg atatgatcgt agtgagtatg
    83761 ggtaagcaaa atcgctaccg gctgttggtt tgtttttttg atttcttgtt tgattcgttc
    83821 cgcatcttct ccagggtcaa tgatcaaaag tgcttcttcg ttgtagacca aataacagtt
    83881 ttcttcaatc attcctgttt ttaatctttc gatatgcatg tgcattcctc cttgatagcc
    83941 aaaacttctt tcatccatta gtataacgca ttcattgcta ggaaacaaaa acaggtactt
    84001 atttctcttt acttatctga attatcagac tatatgaaaa gtatttggat attctaaaga
    84061 gaaggaaagt aagttttcat agcattttaa tatgtccttg ttacattaga ttcatccaaa
    84121 aatccaaatt ctatatccta tatccctgcc taatcagcag ggtgtttttt tatgtttgga
    84181 aagagagctc tttttgctaa actaggtttt ttcaggtaat cttagagaga aagaggtggt
    84241 ggaaatgatc aaacagtcaa aaatatctgt gcggcactta gtagaattta ttttgcgacg
    84301 tggaagtatc gacaatcgta aaaaaagtaa ccatactgca ttagaaggag cgagaatcca
    84361 ccgcaagctc caaaaagatg cgggagaaaa ctatgaaaaa gaagtctttt taaaaacaac
    84421 agttcaatta gatgaatatt acctgatcgt tgaaggccgt gcagacggta ttttcaaaag
    84481 agacggtatt tattatatag atgaaatcaa aacctccgaa ccacgatttg aagatttaga
    84541 accagaacaa gtggaacttt tctttcatca agcaagggtg tatgcctata tctatagtca
    84601 agaacatgat ttacaagaaa taaatctgca attgacttac ttccagacgg cagaagaagt
    84661 gatcacgaga aaggttgaac atcagacaag agagcagtta gaaacttttt ttaaaaagct
    84721 gactgaagat tataaagaat ggcttgtttt tcaagaaaac tggcgcactg tacgcaatgc
    84781 ctctttgatg gctttgaaat tcccccatga tgagtatagg aaaggtcagc gtgaactagc
    84841 ggtagctgct tataaaacga tccgtacgaa acagaaattg tttgtagaag cacctaccgg
    84901 aacaggaaaa acaatctcta cgttattccc cgctttgaaa gctgtagggg aagaagaggg
    84961 agaaaagatc ttttatctaa cggctaaaac aataactaga caagtagctg aagatgctat
    85021 gacagcatta aaagatacag gagctgaagt aaaaagtgtc actttgacgg cgaaagacaa
    85081 gatctgcttt ttagatgaga cgacctgtaa tccagatcag tgcccatatg ccaatggtta
    85141 ttacaatcgg attaatgaag gtttatggga tcttttgaat catgagaatc agatcactcg
    85201 tgaagtcatc gaaacttatg caagaaagca tacactttgt cctttcgaac tatcattaga
    85261 tgtcagtatc tggtgtgacg taatcattgg ggattacaat tatttatttg atccaactgt
    85321 ttatttaaga cgtttttttg aagatgaaaa aaacgaggac tatctgtttt tgattgacga
    85381 agcacataat ttggtgaatc gttcccgaga gatgtattcg gcagaactat cttatgaaaa
    85441 aacgaaacga agtaaggaag ctataccaaa ggaattcaaa aaacttcatc gccgtttcaa
    85501 caaactatta aaagaatttg attcgatccg agaaatagca aaagaagatc attgggatta
    85561 tcatcatcaa aaagcaccgg ctgaatcttt agtaaaggca ggttatcaat taagcgaaaa
    85621 aattaaagaa tggctggcag aatttcctga gcacccatca caagaacaat tgcttcctta
    85681 ttattttgat ttgcttcatt ttttgaaggt cagtgaattt tatgatgatc actacgaaac
    85741 aacagtcgaa aaaacgtatc gcgatctgat agtaaaagag ttttgtattg atccaagctt
    85801 gtttcttgag cagtcgttgg ataaaggaaa aagcagtatt cttttttctg ctagtttttc
    85861 accactctct tattatcagg aaacactggg gggacaaaaa agtctggctt acaaactgcc
    85921 gagtcctttc ccagaaggaa accagcaagt tttcatcgca aattacctag agacgactta
    85981 tcgaaaaagg gaacacagtc tggcaaaatt agtagagacg attcatgctt ttgctgatgg
    86041 aaaggtcggg aattatttcg ttttctttcc ttcttatcaa tatttagatc ttgcggtgga
    86101 agcattcaga cagcaatatc ccgacagcaa tgtgctaatc caagaaacgg acatgaatga
    86161 ggaagaacgc gaacgatttt taacaaaatt tcaaacaaat cccgctgaaa cattgattgg
    86221 attttgcgta cttggcggga ttttttcaga aggaatcgat ttgagagggg accgattgat
    86281 cggcagtatg atcgtaggtg taggtttgcc gcagatgaat catgagcagg aactgatcaa
    86341 atcatattat gatgagaagg aacaccttgg atttgcttac gcttatcagc ttcctggaat
    86401 gaacaaagtc ttgcaagctg gtggtcgagt gattcgtggc atggcggatc aaggaatcgt
    86461 tgtattggca gatcaacgat tttctagttt ttcttatcga cgtttattcc cacaacattg
    86521 gcaaacagca agagaagtac gaagtgttgg ggaattggaa gaaggaatac agcgtttttg
    86581 gttatcaaaa gaagcagtaa atcaaaaaaa cgaggaatga cagacgtcag cctcgttttt
    86641 tgattaacga tagttagtga attgcaactc gattggtaag tcaagtttac gtaataaagc
    86701 aatcacagct tgtagatcat cacggttctt acctgtcact ctaatctgat cttcttggat
    86761 ttgtgctttt actttcagtt tttcattttt gatagctgta gtgattttct tcgcgttttc
    86821 acgatcgatt ccgttgacca aatcggcagt ttgtcgagct ttgccaccta gagcgtgttc
    86881 tgattcggaa aaatggatat ttttgattgg cacatttctt ttgatcagct taccaaataa
    86941 tacatctttg atctgttcga ttttgaaatc atcatcgctc aatacaacta gattgctgtt
    87001 ctctaatttg atttctactg tagaatcctt gaagtcaaag cgattggaca attcttttgt
    87061 tgtttgctga atcgcatttt ttacttcttc tgtattgact tctgatacaa tgtcgaagct
    87121 agcatctttt gccataggaa ccctcctgat atacatataa atatttacca tacatctatc
    87181 ttatcatagg attagggcag attcttacct gtttgctaaa attcttctca tttgagttcg
    87241 aagtatttta ttttaataga taaactgtta ttcttacatt tggaatacca aagtagggga
    87301 gaggtgcttg tgagtaaaat tatgactgcg tatcataaaa atgaaagatt aaagaaaata
    87361 gtggttattt tgataaccgg attgaccgct gcggtcgctt taaattattt tttgattcca
    87421 gccaatgtct tttctgcagg gatgaatggg atcgctcaaa tcatttcctc gcttttatat
    87481 gaatggtttc atatcaagat agacacagga acatttattt ttcttttgaa tatccctgtg
    87541 tttgtattag ggtttctcaa agtaggaaaa cgagcaacga tccttagttt tgtgaatgtt
    87601 gtatgtgtat cggtgatgac gatgctgctt ccagtcggac agatcactga taatattttg
    87661 atgaatgccc tagtaggcgg tgttttatta ggtcttggcg taggattatc tttaaaaatg
    87721 ggctttacaa ctggtgggat ggatatcatc tctcttgtac tttcacaaac aactggaaaa
    87781 acagtcggaa actacatgct gattctaaat ggtatcattg tagtcatcgc aggcttcttc
    87841 tttaactggg aaagtgcctt gtatacgatt atttccattt atgcaatgac tcaagtaatt
    87901 gatgccatcc acacgagtca tcaaaaagta acagcaatga tcgttaccgt caagccagaa
    87961 gaggtaacag aagaactagc aaaacggatg gtacgtggaa tgacattact gccgtctgtc
    88021 ggtggctatt caaaaaaaca agggaacatg atcatgatgg tcatcacccg ctacgaaatg
    88081 tatgatcttg atcagatcgt tcatgaaatc gacgacgatg catttatcaa tattttacca
    88141 actcattcag tatttggccg gtttgcaaat gaaaacgaac aaaaaatgta tcgaacaact
    88201 ggcgtattgc cagaaataaa aaatcgttca caaaaaaaat gaggaatcag gtttatttta
    88261 gaataaattt aatctattac atctaataag aacattttta taaatttaaa cgagaatctt
    88321 acttctaaat tctcatttac aagcagctaa aaaaagagta tgataaataa aaatcgtgtt
    88381 aaggagtgtc gtacgatgag cgaagcaaac caagaacggt ctggacaaga aatagaacta
    88441 atcaaagaac gtattcttgc tgccttggaa atggtgattg atcctgaatt aggaatcgac
    88501 atcgtcaatt taggcttgat ttatgatata gaattcaatc ctgaaaatgg agaaacagtc
    88561 attaagatga ctctaacaac tatgggctgt ccattagcag atattttaac agaatctatc
    88621 catgacgcat taaaagaagt gccagaagta acgaaagcag aagtcaaact agtctggtat
    88681 ccagcatgga cgacagataa gatgagccgt tatgcacgga ttgcgttggg gatacgatag
    88741 aaatcttggc tgactagcta tgagaagcaa ataggaaaaa caaaaaagcc ttttatcctt
    88801 tctagaagaa aagagataaa aggtttcttt gtttataaaa ttttgtctgc tatattataa
    88861 gttaattaaa taaatgtgtt ctattgataa aggacattca aatccctttc cttttggaat
    88921 ccttcttttt tacatcagtt tgattttcgt atagtattct ttctcatctt cacgataaat
    88981 cgcagcccca tttttttgtt gtgctttaag actgccaaga ttttttttat ttacagacaa
    89041 aagtgcctca tcaatgccga ttttttttgc ctcttgtagt actaatgcta atccttgtgt
    89101 ggcatatcct tttttacgat aattagggga gatgccgtaa ccaatatggc cagcgccgtt
    89161 tcttaatgtt tcgttcagtt tatggcgcaa attaaaaatt cctacatact catgttcatc
    89221 actttctaaa ataaagacgg ttgcgggaac gtaactctca ggaagatcga ttcctaaaga
    89281 cgttttttcg cattttttta cataatctaa aaattcagca aatgtatagc cataagcatt
    89341 gttgataaat ccactctcat ttggtccaaa gctagtttgt agctgataag ctttctttaa
    89401 atctgcttcc catagtttga tcagtttcat cgtattcacc tctttaagta accttattca
    89461 tttgttttct actatagcac tattgttgta aatagccatg cctattttta tttattgtgt
    89521 catatcgtat taagaatcat cgaacaatac aaatatgaat tacaataaaa aaattatttg
    89581 aagttcgttc attcgttact tatgatctct agaagaaaga aaacgtgaat tacttcagcg
    89641 tctagaattc cagaaggata gtaatcaaca gaagaaataa tcaatatcca aatgaaagaa
    89701 gatagctgaa tcgagaaaaa gaggaaaaaa gaaatgaaga aaaaaataaa atagttacta
    89761 atcccagagt cgttcgttta acattgaaat cgatcatatg gataaaacag attttttcac
    89821 caaccctcaa tagatgatgg agttgctcgg atgaattatt tgtgtagatg gcataaggga
    89881 gggcgtacag aaatgaaaaa gaacaaaaat atgttcttga caaaaaacac atgtaatcct
    89941 aaactaaaag atgtgatgcg gctatggcgg aattggcaga cgcgctagct tcaggcgcta
    90001 gtgagggtga cctcgtggaa gttcgagtct tcttagccgc ataatttgtt tttttataaa
    90061 gagaaggtac acctggagcg atgagaaaga aaataacata ttatctaaaa gaatatagga
    90121 aaaattttaa acaacggaac cagattcaaa taaatcaaaa aaaatttgtg tgaaggtggg
    90181 acagtttaaa acctaataga ttgattcaaa tagtagattt atagattctg atacaagaaa
    90241 tactggcaaa cgatagttaa ggaataaaga ctaaacttaa actcaaaaag aggtcatgcg
    90301 aaagaata
//
LOCUS       DARPZJ010000005        89619 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.005, whole genome shotgun sequence.
ACCESSION   DARPZJ010000005 DARPZJ010000000
VERSION     DARPZJ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 89619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.005"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(552..2165)
                     /locus_tag="SLE23_000430"
     CDS             complement(552..2165)
                     /locus_tag="SLE23_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8467363.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="SLE23_000431"
     CDS             complement(2306..3214)
                     /locus_tag="SLE23_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467364.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="SLE23_000432"
     CDS             3397..4521
                     /locus_tag="SLE23_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8467365.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4748..5665
                     /locus_tag="SLE23_000433"
     CDS             4748..5665
                     /locus_tag="SLE23_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8467366.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="SLE23_000434"
     CDS             5658..6491
                     /locus_tag="SLE23_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8467367.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="SLE23_000435"
     CDS             6574..7692
                     /locus_tag="SLE23_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEI8467368.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7686..9584
                     /locus_tag="SLE23_000436"
     CDS             7686..9584
                     /locus_tag="SLE23_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HEI8467369.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9578..10801
                     /locus_tag="SLE23_000437"
     CDS             9578..10801
                     /locus_tag="SLE23_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEI8467370.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..12821)
                     /locus_tag="SLE23_000438"
     CDS             complement(10887..12821)
                     /locus_tag="SLE23_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8467371.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13047..13703
                     /locus_tag="SLE23_000439"
     CDS             13047..13703
                     /locus_tag="SLE23_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEI8467372.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13777..14130)
                     /locus_tag="SLE23_000440"
     CDS             complement(13777..14130)
                     /locus_tag="SLE23_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEI8467373.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14322..15251
                     /locus_tag="SLE23_000441"
     CDS             14322..15251
                     /locus_tag="SLE23_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEI8467374.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15262..16098
                     /locus_tag="SLE23_000442"
     CDS             15262..16098
                     /locus_tag="SLE23_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEI8467375.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16346..17122
                     /locus_tag="SLE23_000443"
     CDS             16346..17122
                     /locus_tag="SLE23_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8467376.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17298..18041
                     /locus_tag="SLE23_000444"
     CDS             17298..18041
                     /locus_tag="SLE23_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467377.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18034..19614
                     /locus_tag="SLE23_000445"
     CDS             18034..19614
                     /locus_tag="SLE23_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEI8467378.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19865..20344)
                     /locus_tag="SLE23_000446"
     CDS             complement(19865..20344)
                     /locus_tag="SLE23_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEI8467379.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20360..21112)
                     /locus_tag="SLE23_000447"
     CDS             complement(20360..21112)
                     /locus_tag="SLE23_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEI8467380.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21229..21299
                     /locus_tag="SLE23_000448"
     tRNA            21229..21299
                     /locus_tag="SLE23_000448"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21261..21263,aa:Gly,seq:ccc)
     gene            21660..22385
                     /locus_tag="SLE23_000449"
     CDS             21660..22385
                     /locus_tag="SLE23_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEI8467381.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22640..22906
                     /locus_tag="SLE23_000450"
     CDS             22640..22906
                     /locus_tag="SLE23_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEI8467382.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22903..23334
                     /gene="ruvX"
                     /locus_tag="SLE23_000451"
     CDS             22903..23334
                     /gene="ruvX"
                     /locus_tag="SLE23_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEI8467383.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23359..23664
                     /locus_tag="SLE23_000452"
     CDS             23359..23664
                     /locus_tag="SLE23_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEI8467384.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23745..24890)
                     /locus_tag="SLE23_000453"
     CDS             complement(23745..24890)
                     /locus_tag="SLE23_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8467385.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24951..25598)
                     /locus_tag="SLE23_000454"
     CDS             complement(24951..25598)
                     /locus_tag="SLE23_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467386.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25792..26085
                     /locus_tag="SLE23_000455"
     CDS             25792..26085
                     /locus_tag="SLE23_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467387.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26129..26440
                     /locus_tag="SLE23_000456"
     CDS             26129..26440
                     /locus_tag="SLE23_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467388.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26437..27061
                     /locus_tag="SLE23_000457"
                     /pseudo
     CDS             26437..27061
                     /locus_tag="SLE23_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27202..27360
                     /locus_tag="SLE23_000458"
     CDS             27202..27360
                     /locus_tag="SLE23_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467389.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27361..27723
                     /locus_tag="SLE23_000459"
     CDS             27361..27723
                     /locus_tag="SLE23_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467390.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27760..28608
                     /locus_tag="SLE23_000460"
     CDS             27760..28608
                     /locus_tag="SLE23_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEI8467391.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28598..30073
                     /locus_tag="SLE23_000461"
     CDS             28598..30073
                     /locus_tag="SLE23_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEI8467392.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30339..30746
                     /locus_tag="SLE23_000462"
     CDS             30339..30746
                     /locus_tag="SLE23_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HEI8467393.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30749..30964
                     /locus_tag="SLE23_000463"
     CDS             30749..30964
                     /locus_tag="SLE23_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467394.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30968..31348
                     /locus_tag="SLE23_000464"
     CDS             30968..31348
                     /locus_tag="SLE23_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEI8467395.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31482..31637
                     /locus_tag="SLE23_000465"
     CDS             31482..31637
                     /locus_tag="SLE23_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HEI8467396.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31706..32179
                     /locus_tag="SLE23_000466"
     CDS             31706..32179
                     /locus_tag="SLE23_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEI8467397.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32176..33870
                     /locus_tag="SLE23_000467"
     CDS             32176..33870
                     /locus_tag="SLE23_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEI8467398.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33836..34021
                     /locus_tag="SLE23_000468"
     CDS             33836..34021
                     /locus_tag="SLE23_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467399.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34025..35199
                     /locus_tag="SLE23_000469"
                     /pseudo
     CDS             34025..35199
                     /locus_tag="SLE23_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            35192..36715
                     /locus_tag="SLE23_000470"
     CDS             35192..36715
                     /locus_tag="SLE23_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEI8467400.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36771..37055
                     /locus_tag="SLE23_000471"
     CDS             36771..37055
                     /locus_tag="SLE23_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEI8467401.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37042..37377
                     /locus_tag="SLE23_000472"
     CDS             37042..37377
                     /locus_tag="SLE23_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEI8467402.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37672..38298
                     /locus_tag="SLE23_000473"
     CDS             37672..38298
                     /locus_tag="SLE23_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467403.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39040..39876
                     /locus_tag="SLE23_000474"
     CDS             39040..39876
                     /locus_tag="SLE23_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEI8467404.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39941..40375
                     /locus_tag="SLE23_000475"
     CDS             39941..40375
                     /locus_tag="SLE23_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467405.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40443..41765)
                     /locus_tag="SLE23_000476"
     CDS             complement(40443..41765)
                     /locus_tag="SLE23_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEI8467406.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41919..43559)
                     /locus_tag="SLE23_000477"
     CDS             complement(41919..43559)
                     /locus_tag="SLE23_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HEI8467407.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43889..44359
                     /locus_tag="SLE23_000478"
     CDS             43889..44359
                     /locus_tag="SLE23_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HEI8467408.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44988..46091
                     /locus_tag="SLE23_000479"
     CDS             44988..46091
                     /locus_tag="SLE23_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEI8467409.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46375..47055
                     /locus_tag="SLE23_000480"
     CDS             46375..47055
                     /locus_tag="SLE23_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEI8467410.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47145..48179
                     /locus_tag="SLE23_000481"
     CDS             47145..48179
                     /locus_tag="SLE23_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEI8467411.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48193..48528
                     /locus_tag="SLE23_000482"
     CDS             48193..48528
                     /locus_tag="SLE23_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467412.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48512..50974
                     /locus_tag="SLE23_000483"
     CDS             48512..50974
                     /locus_tag="SLE23_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467413.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGIPLQFDVTANVAKMTENGDKYDTSPN
                     KILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGGNLNPGA
                     YAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLTMGLTEG
                     RFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQGGLLSP
                     VALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIHYRLYSK
                     GTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTNMYPSFA
                     YKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQENVTFT
                     LTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLSKIGDTI
                     HLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTILVPKQEL
                     TLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLTSLFKND
                     QGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLLEVNSST
                     NAQPGATYQGMVTWELTAGPTS"
     gene            51030..52589
                     /locus_tag="SLE23_000484"
     CDS             51030..52589
                     /locus_tag="SLE23_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467414.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52586..53950
                     /locus_tag="SLE23_000485"
     CDS             52586..53950
                     /locus_tag="SLE23_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8467415.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54121..55191
                     /locus_tag="SLE23_000486"
     CDS             54121..55191
                     /locus_tag="SLE23_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467416.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55206..55874
                     /locus_tag="SLE23_000487"
     CDS             55206..55874
                     /locus_tag="SLE23_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467417.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55894..56472
                     /locus_tag="SLE23_000488"
     CDS             55894..56472
                     /locus_tag="SLE23_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8467418.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56875..57786
                     /locus_tag="SLE23_000489"
     CDS             56875..57786
                     /locus_tag="SLE23_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEI8467419.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58042..58944)
                     /locus_tag="SLE23_000490"
     CDS             complement(58042..58944)
                     /locus_tag="SLE23_000490"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEI8467420.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTKNISQLSVLGSDEVGNGSYFGPLT
                     VCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKYNEIQP
                     KYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQLQEKLY
                     FVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKLLEKGG
                     MPMLEKYAKLHFANTEKALKLLKK"
     gene            59146..59583
                     /gene="zapA"
                     /locus_tag="SLE23_000491"
     CDS             59146..59583
                     /gene="zapA"
                     /locus_tag="SLE23_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEI8467421.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59641..60189
                     /locus_tag="SLE23_000492"
     CDS             59641..60189
                     /locus_tag="SLE23_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEI8467422.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            60304..62664
                     /locus_tag="SLE23_000493"
     CDS             60304..62664
                     /locus_tag="SLE23_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEI8467423.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62751..63065
                     /gene="trxA"
                     /locus_tag="SLE23_000494"
     CDS             62751..63065
                     /gene="trxA"
                     /locus_tag="SLE23_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEI8467424.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63247..65025
                     /gene="uvrC"
                     /locus_tag="SLE23_000495"
     CDS             63247..65025
                     /gene="uvrC"
                     /locus_tag="SLE23_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEI8467425.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65170..66069
                     /locus_tag="SLE23_000496"
     CDS             65170..66069
                     /locus_tag="SLE23_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467426.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66062..67324
                     /locus_tag="SLE23_000497"
     CDS             66062..67324
                     /locus_tag="SLE23_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467427.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67485..69383
                     /locus_tag="SLE23_000498"
     CDS             67485..69383
                     /locus_tag="SLE23_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HEI8467428.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69682..70401)
                     /locus_tag="SLE23_000499"
     CDS             complement(69682..70401)
                     /locus_tag="SLE23_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEI8467429.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            70738..71070
                     /locus_tag="SLE23_000500"
     CDS             70738..71070
                     /locus_tag="SLE23_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467430.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71057..73060
                     /locus_tag="SLE23_000501"
     CDS             71057..73060
                     /locus_tag="SLE23_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEI8467431.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73079..73549
                     /locus_tag="SLE23_000502"
     CDS             73079..73549
                     /locus_tag="SLE23_000502"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEI8467432.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73570..74154
                     /locus_tag="SLE23_000503"
     CDS             73570..74154
                     /locus_tag="SLE23_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEI8467433.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74169..75155
                     /locus_tag="SLE23_000504"
     CDS             74169..75155
                     /locus_tag="SLE23_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEI8467434.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75145..75456
                     /locus_tag="SLE23_000505"
     CDS             75145..75456
                     /locus_tag="SLE23_000505"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEI8467435.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75478..77259
                     /locus_tag="SLE23_000506"
     CDS             75478..77259
                     /locus_tag="SLE23_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEI8467436.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77252..78628
                     /locus_tag="SLE23_000507"
     CDS             77252..78628
                     /locus_tag="SLE23_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEI8467437.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78635..79270
                     /locus_tag="SLE23_000508"
     CDS             78635..79270
                     /locus_tag="SLE23_000508"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEI8467438.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79300..80655
                     /locus_tag="SLE23_000509"
     CDS             79300..80655
                     /locus_tag="SLE23_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEI8467439.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKFAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKITIHSKIALTVTGTLLLGGFVVFFFTERNGETLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80847..82241)
                     /locus_tag="SLE23_000510"
     CDS             complement(80847..82241)
                     /locus_tag="SLE23_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEI8467440.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQKLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQNKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82333..83304
                     /locus_tag="SLE23_000511"
     CDS             82333..83304
                     /locus_tag="SLE23_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HEI8467441.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKDKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSATLTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83301..84082
                     /locus_tag="SLE23_000512"
                     /pseudo
     CDS             83301..84082
                     /locus_tag="SLE23_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(84251..84622)
                     /locus_tag="SLE23_000513"
     CDS             complement(84251..84622)
                     /locus_tag="SLE23_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8467442.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TTPSYYFVIDPDGYKIEVIRG"
     gene            84756..85199
                     /locus_tag="SLE23_000514"
     CDS             84756..85199
                     /locus_tag="SLE23_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEI8467443.1"
                     /translation="MDKPIFGEKKQSANYQTRYAAYIVIERDKRIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85242..86051)
                     /gene="yidA"
                     /locus_tag="SLE23_000515"
     CDS             complement(85242..86051)
                     /gene="yidA"
                     /locus_tag="SLE23_000515"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEI8467444.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86070..87437)
                     /locus_tag="SLE23_000516"
     CDS             complement(86070..87437)
                     /locus_tag="SLE23_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8467445.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87421..88251)
                     /locus_tag="SLE23_000517"
     CDS             complement(87421..88251)
                     /locus_tag="SLE23_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEI8467446.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88414..88851
                     /locus_tag="SLE23_000518"
     CDS             88414..88851
                     /locus_tag="SLE23_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEI8467447.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88927..89547
                     /locus_tag="SLE23_000519"
     CDS             88927..89547
                     /locus_tag="SLE23_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEI8467448.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     EKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
BASE COUNT        29546 a        15165 c        18457 g        26451 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgccaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
    12481 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
    12541 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
    12601 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
    12661 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
    12721 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
    12781 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
    12841 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
    12901 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
    12961 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
    13021 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
    13081 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
    13141 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
    13201 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
    13261 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
    13321 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    13381 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    13441 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    13501 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    13561 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    13621 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    13681 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    13741 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    13801 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    13861 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    13921 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    13981 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    14041 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    14101 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    14161 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    14221 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    14281 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    14341 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    14401 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    14461 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    14521 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    14581 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    14641 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    14701 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    14761 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    14821 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    14881 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    14941 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    15001 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    15061 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    15121 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    15181 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    15241 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    15301 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    15361 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    15421 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    15481 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    15541 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    15601 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    15661 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    15721 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    15781 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    15841 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    15901 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    15961 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    16021 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    16081 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    16141 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    16201 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    16261 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    16321 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    16381 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    16441 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    16501 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    16561 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    16621 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    16681 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    16741 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    16801 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    16861 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    16921 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    16981 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    17041 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    17101 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    17161 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    17221 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    17281 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    17341 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    17401 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    17461 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    17521 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    17581 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    17641 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    17701 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    17761 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    17821 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    17881 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    17941 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    18001 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    18061 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    18121 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    18181 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    18241 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    18301 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    18361 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    18421 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    18481 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    18541 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    18601 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    18661 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    18721 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    18781 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    18841 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    18901 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    18961 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    19021 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    19081 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    19141 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    19201 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    19261 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    19321 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    19381 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    19441 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    19501 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    19561 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    19621 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    19681 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    19741 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    19801 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    19861 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    19921 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    19981 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    20041 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    20101 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    20161 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    20221 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    20281 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    20341 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    20401 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    20461 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    20521 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    20581 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    20641 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    20701 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    20761 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    20821 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    20881 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    20941 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    21001 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    21061 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    21121 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    21181 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    21241 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    21301 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    21361 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    21421 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    21481 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    21541 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    21601 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    21661 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    21721 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    21781 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    21841 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    21901 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    21961 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    22021 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    22081 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    22141 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    22201 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    22261 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    22321 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    22381 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    22441 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    22501 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    22561 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    22621 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    22681 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    22741 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cggcctacat
    22801 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    22861 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    22921 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    22981 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    23041 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    23101 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    23161 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    23221 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    23281 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    23341 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    23401 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    23461 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    23521 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    23581 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    23641 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    23701 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    23761 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    23821 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    23881 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    23941 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    24001 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    24061 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    24121 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    24181 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    24241 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    24301 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    24361 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    24421 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    24481 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    24541 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    24601 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    24661 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    24721 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    24781 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    24841 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    24901 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    24961 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    25021 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    25081 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    25141 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    25201 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    25261 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    25321 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    25381 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    25441 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    25501 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    25561 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    25621 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    25681 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    25741 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    25801 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    25861 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    25921 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    25981 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    26041 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    26101 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    26161 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    26221 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    26281 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    26341 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    26401 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    26461 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    26521 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    26581 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    26641 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    26701 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    26761 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    26821 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    26881 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    26941 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    27001 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    27061 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    27121 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    27181 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    27241 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    27301 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    27361 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    27421 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    27481 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    27541 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    27601 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    27661 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    27721 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    27781 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    27841 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    27901 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    27961 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    28021 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    28081 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    28141 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    28201 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    28261 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    28321 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    28381 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    28441 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    28501 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    28561 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    28621 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    28681 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    28741 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    28801 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    28861 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    28921 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    28981 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    29041 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    29101 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    29161 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    29221 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    29281 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    29341 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    29401 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    29461 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    29521 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    29581 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    29641 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    29701 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    29761 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    29821 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    29881 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    29941 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    30001 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    30061 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    30121 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    30181 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    30241 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    30301 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    30361 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    30421 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    30481 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    30541 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    30601 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    30661 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    30721 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    30781 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    30841 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    30901 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    30961 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    31021 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    31081 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    31141 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    31201 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    31261 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    31321 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    31381 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    31441 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    31501 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    31561 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    31621 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    31681 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    31741 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    31801 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    31861 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    31921 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    31981 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    32041 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    32101 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    32161 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    32221 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    32281 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    32341 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    32401 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    32461 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    32521 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    32581 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    32641 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    32701 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    32761 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    32821 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    32881 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    32941 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    33001 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    33061 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    33121 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    33181 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    33241 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    33301 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    33361 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    33421 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    33481 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    33541 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    33601 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    33661 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    33721 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    33781 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    33841 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    33901 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    33961 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    34021 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    34081 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    34141 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    34201 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    34261 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    34321 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    34381 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    34441 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    34501 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    34561 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    34621 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    34681 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    34741 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    34801 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    34861 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    34921 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    34981 ttccgacagt tactagagac tgatcctgaa acaaaagtaa aaaatgtatt ggatcaggtc
    35041 aaagggtcac ttctcacgat taatgagggg cggtcgaaaa tggggctacc ccccatggat
    35101 ggtggcgatc gtttactagc aagtttgaac tttacgtatt tagatacgtt ggagaaatat
    35161 caattaaaag aacaggaagg agttacacca gttgaataat gaagaagaaa aggaaaaacg
    35221 gctgacagaa gaagctgagc taacagccga ttctcccaaa gtagagaaag aaaatgaaaa
    35281 acaaccaaca gacggcaaaa ctatttcagg ctatgcgttg aaattcgggc aaccgtcaaa
    35341 agatttaggc ggctttgtag aagtgattac acccgaagca ttaaaagagg tggatttatc
    35401 aaatgtgttc ttattatatg gacacgatta ttcaaagcca ctagctagtg tcaaagcagg
    35461 tacgttgaaa ttgaatgtcg atgatacagg attacatttt gaagcagagc taaccgacac
    35521 gacctattca aatgatgtgt atgagaatat ctcaaaaggg gttgttgatt ctatgtcctt
    35581 tgggttcgtg cttggattag attcattcga caaaaaagaa gatggcacaa ttgaacgatc
    35641 aatagataaa atcaaagcac ttaatgaaat tagtgtcgtg accgttcccg cttatgattc
    35701 atcaaatgtc caagtaaata agcgttctta cgaatcgttt atgagtaaca accaagcaaa
    35761 acaaacaaac aatagcttag aatccacttc taaagcacaa aaggagagta ataacatgga
    35821 aaaaacttta atcgataacg aaaaaacaga attgcgtggg tatgaagaat atatccgttc
    35881 acaaggcgaa gtgcgtgatg gagtcactac tgtaaatgca gcggcagttg ttcccgaaga
    35941 agtaatcggt gaagtctttg atttgaaacg ttcaaattat aacttagctc aatatgcaac
    36001 agtaaaaaca gtatcaaatg gacaaggtaa atatccagta gcaactaacc aacaagcagt
    36061 gttagcaaca aaagctgaac ttgctgaaat tggtgatatt gacgctgaaa tgtttacttc
    36121 agttgattat aaagtagaaa ctcgtgctgg taagattgcc ttatcaaatg aggttgtgga
    36181 agattcagca gtgaatattg tacaagaggt caaagatcag ttagcgaaat tggtagaaaa
    36241 cactgacaat aagcatatca tggatttatt aaaaacattc actaagaaaa cggctgctac
    36301 gttggacgat ttgaaacaac tatacaatgt ggcattagac ccagcattaa ataaaatggt
    36361 aattctaaac caaagcggat attaccacct agatacattg aaagattcag atggacgtta
    36421 cattttacaa cccgatgtga cagcacctag tggtaaatca ttattcggta tgccagtagt
    36481 attgattgca gatacattgt ttgccaatcc taaagctgga acattcccta tgattatggg
    36541 ggatattgca caatctatct ttgttgctcg tagaaatcaa gtaacgactc aatgggaaaa
    36601 attcgattac tactcacaag gacttgcagt gatcgttcgc aacgattata agaaaattga
    36661 tcaaaatgct tcagtgtata ttgagtttac gccagttgta acaccaaaag tatagaaaaa
    36721 tattgggcgg cggtttatcc cactgccttt ttttcattag gagagataaa atggtaattt
    36781 tggatagcat aaaaaaaagt atgcggatcg atcacactat tgatgatgac tttattcaac
    36841 aattgattga tacagcaggc gaatatataa aaagtgctat tgatagtagc gcaacggata
    36901 aagatatgga taattatcag caatttgatt tggcggtgtc attacttact caacattggt
    36961 atttgaaccg tcaagaagcc agcagcgaac ggataccagt aacggtacaa gcattagtac
    37021 aacaaatgag aggtgcttat tatgccaatc attaagaatg taaatgaatt gactgagaga
    37081 gtcaagttta aaaagacaaa acgggtaaaa gatgaagatg ggcagatggt ggatagtgaa
    37141 gaaactgtat ttgaatgttg ggctaatgtg cgttcacaaa tgctaaaaga cgtgcttgct
    37201 agtgtaggta ccattcttga aggaacgttg acgtttatta ttcgatacga tcaagattat
    37261 gaactaacaa acgatatgaa agtagcttgg aaaaacaaga gttataaaat tatttcaatc
    37321 aatgaaggaa cggcgtttaa agattataca acgatcatag ctaaacagat ttcttagaat
    37381 gattacactt gtaaacgttg tgggtattta gtataattaa ggtagtaaat gaagggttag
    37441 ctgcctgaat tttgcaagac ttagctagtc gaaatctatt gttggactga aaattgtagg
    37501 tgtggttgca aacatgctgg actaagaaag atgatagatg atgaacgttc aattttaata
    37561 caggcatgct aggactgatt ggatggtttt ggcaagctga ttgtgtagaa atcaaagaac
    37621 acgtctgttg tggacgtgtt ttttttgtta taattcaaaa gaggtgattt aatggacaaa
    37681 gcagagttta caaattttta ttggaagtat tatctacatt tagaaaatga gtttattaat
    37741 accacagatt ttgtgatgct cgatgagaat aatttcaaaa cattctctat tgaatatcaa
    37801 aaactactac tagcgattgg ttcggagtgt gagattattt tcaaagaact ttgcggattt
    37861 gatagcagta gcaataaaag cataactgat tttaaagctg ttattaaatc tagcgaatta
    37921 atgtgtttgg ataatggtgt tagggttatg aattctttaa cattgacttc actaaaacct
    37981 tttggagatg ggtggcctga agatacacca gattggtgga aaatatataa cagagtaaaa
    38041 catggtcgtt cttcaaatta taaggaagca aatttggaaa atgtgttgta tgctttagca
    38101 agtctatatt tattagagga atatttgcat aagaaagtaa tactagaagg tgaagtagac
    38161 tttataagtc cagagtcaaa tctatttacg ttatcttggg aaagaaaaca ttcgtcgatg
    38221 caaaaagtga cgtttgaaaa agtggattca aattatgtag ctccactcat tgattttaaa
    38281 gaacaagaag aaatttaaaa acccccacgg cttattgaag tttttgtatg ccatattgta
    38341 tgccatttgg tttaaatcgc ttgaaaaata gtgatagata actctaattc atttagtcat
    38401 aaacgctgtt ttgataacct ttatagttct ttgatatggg tttctcattc atggcggaag
    38461 aagaagaata gaacaaaaga atgaattaat aagatataaa aaaagggatt gtgacaaacg
    38521 tcttgtcaca atcccttttt ccaaataaac gatgttcaat cagctgcccc tcggcattcg
    38581 ctcgaaaaac ggcgaaatat gaagaactat tttgccattt gtttctctaa taatcaggtc
    38641 aaaacgttga cttcacagtc tcttccttaa acggtgttct cctgccaact cctcggtcac
    38701 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg
    38761 agctgaacgg caggctcacg acctctttct taaacggtgt tcaaaagctt gcatctgcgg
    38821 taataagttc aaccaaacga aaattatgag gagctatttt tgtttggctg ttcttattac
    38881 ttgatgcagg acagcttttt cacaacctct tttcgtttag cactaaattt ccttaaaaag
    38941 tagaaaagct ttcgaagcct cgtttgtttc ttttactgta taataaaaga aaagagtaac
    39001 aatcgctaaa agatataaac aagagaaagg aaatacaaga tgattggtct gatttatttt
    39061 gtggtgatcg ttctggcgaa cacagttggc gctatttccg ggatgggtgg aggcgtgttg
    39121 atcaaaccga ttcttgatct tatcggcgcc cattctgttg cagggatttc tttttactca
    39181 acagttgcgg tattcacgat gtccattgtt tcgactgtgc gacaagtatc aagcgggaaa
    39241 tcactgaatt ggcagattgt cggttgggta tctagtggag ctgttgttgg aggagtagtc
    39301 ggcaacattg tattcgaagt ttttttacag ttatttgaaa acgagaagca tgtgcagctg
    39361 atccaaattt ttttgacggt attgaccttg gtttttgcgt tcttctacac caagcatcat
    39421 cagccaaaat ttcatttgac gtcatggact tggtacctta tatgtggggg ggttctgggc
    39481 tttttagcta gttttttagg tattggtggt ggaccagtca atgtttcttt gttgatgctg
    39541 atgtttgcat tgccaataaa agaagcaaca ctatattctc tatctacgat tttcttttct
    39601 caactggcaa aattggtaac gattgcttta acaagtagct ttatgcgctt tgatttatct
    39661 atgttgtttt atgttatccc cgctgctgtt attggaggtt tgtggggagc aagatttagc
    39721 agggttttgt ctccaaaaaa agtgaccttt atttttcaag taattgtcct cgtggttctt
    39781 ttggtcaatt gttacaatgc ctttgtcatc ttacaaacat taggagaatc tagactaacg
    39841 caagtcaaaa tcactgaaac atattgttct aaatgaaaaa aagagtatac tatgataaaa
    39901 aaattcattt taaaaaatca gaaattggct ggtgatttgg atgttacggg aaatgcgttt
    39961 agaagatgca gaagcactac gtgaaatcaa tgcggatcaa ttagggtatg atataccatt
    40021 aaccgttacg gtgagacaaa tgaagaaact gctgaaggag ccagagaaaa attttttctt
    40081 ggtttatgaa gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga
    40141 atcgattttt agcgatccaa tgttcaatat tatggcactt gctgtgtcta aatatgctga
    40201 aaaaagaggc atcggaaagg ctttgatgac tggcgtagaa gaagaagcga aaaaacgagg
    40261 aataacgaca ataaggctta attctgcaga atacagagta gaagcacacc aattttatga
    40321 acacatcggt tatcattccg ataaaatgca aaaaagattt ttgaaaatcc tgtaaatctt
    40381 tatcaaaaaa atacccgatc accaagccga tacttgatga tcaggtattt ttgttttttt
    40441 gactaagaaa gtaattgcat caagaaacca gagatgatca aaacgatggc accaccaagt
    40501 cgattgccca tttgagcaaa agcaataagt tccatccgat tagctgcaga taagacggct
    40561 acatttcctg ttccgcccat cgagttgttg cataagccag cagtaatagt tgattcaatt
    40621 ggatataaac caaacaaacg accgacaaat cctgaaacaa ctgaaatcgc gataacactt
    40681 gtcagacata agacaacaaa ttgccatgtc aaagcagaag ctaatacatt cagattcagc
    40741 aacgcaatac cgataccggc aagaacagct gctgtcaagt ttttgacaat caagttattg
    40801 aacatgatag ctgcatcttc ataatactct ggtaataggt tggcgatttt acagatgaca
    40861 acgataataa tcataaatgc gtaagcatgg actttaggaa caaaatagtt accaatttgt
    40921 cctaagatga agaaagtcaa tgataccatc aaaccaacac ctaactgtgg aatggaaggt
    40981 ttcacagttc gaggttttcc atcgccaaga tcgccttttt ccattaattt accattgccg
    41041 ttgaattttg gcattgattg tccagcacga gcaactaatg ctgcaccgat gatagctaag
    41101 acatttgtca ttgctgtcgc aggaatcagg cgggaaatga tagaagaagc atccgtacct
    41161 aaaacatttg cataaatcgt tgataaagga acggctccgg ctccaacacc accagccatc
    41221 gcaggtaatg agatgtataa aacggaattt gcaaaaccat ttccgataag catgcccacg
    41281 agtcctacgg caaaaaagga gacgaccatt gaaataagtg caacgggaat aaaacgaaca
    41341 gaagctttca tcaatagatt acggttcata ccaaggatgc taccagtaat caaggcagca
    41401 atataaaagt cccaaaagcc catattgctg acaaagtttt ctgtggattt cactacatat
    41461 tcaggtaaga tcccaaatgt agcaatcgca gcagaagcga agatcgcaaa aacggaacca
    41521 ccacccaaat aacttttgac gatagggatt tttgtcccga taaaatgaaa taaattaccg
    41581 aaaataacca aaactgcgat tggtccaatc atattcgtcg gtaatttccc taaagccatt
    41641 gcaatgatca ggacaaggac catgatcaaa taaagtggca aacttacgcc ggtgattttt
    41701 gtggaccaaa aaccttcttt tttcttttcc tcaactgcag ttgcagttgt tgttttttgt
    41761 gccattttta cagatccttt cttattctgt atcatatgaa aaaagccaaa gaaaagcgac
    41821 aaaagagcag gagttggctg gccgctgttt tgccgcagtc gcttttttct ttttagacgt
    41881 catacaaagt ttctgtatgt tcttttacta taacgatctt aatcttctaa agatttatat
    41941 tcaggaaccc atttagcaga ttcaactgct tctttgatat ccgtgatttc ttcacgattc
    42001 aagttttgtg cgacaactga ttttgcgaca gtttcagcaa tcgtttgaga aaattcagtg
    42061 atttttgcta ctggaggcaa gatagctgct cctggttttg ttacatcaac gattccgcct
    42121 aatgctcgac tagcttgaga aatgatttca gcatttactc gtgtagctgt tgaagcaatc
    42181 aaaccaagtc ctaaacctgg gtacatcaaa gcattatttg cttgaccgat ttggtaagtt
    42241 acaccattat attcaacatc agcagcaggg atacctgttc caactaatgc ttttccgtcc
    42301 gtccattcta ttaaatcttt tgcttttgct tctgccaatt ttgttggatt agacaaaggc
    42361 atgatgatcg gacgtggtgt atgagcagcc atttctttca cgatttcttc agtgaatgct
    42421 ccaggttggg tagaagtacc aatcatgatt gtcggatgga tcgcttttac aactgcttct
    42481 aagtttgtca attcatcagc attagtgaaa tctgagcgtt tgcgagcgaa tgggatttga
    42541 ccaggagtca atccttctgt atcttcaaac aataaacctt gtttatctac ttgatagaaa
    42601 tgttggcgtg cttcttcttc aggtacacct tgacggatca tctcatctaa aaggatgttt
    42661 gcgataccca caccagcagt accagcacca aatgtcaaaa ttatttgatc tttcaattgt
    42721 tcaccggata tattcaatcc gcctaataca cctgctagga caacaattcc tgtaccttgg
    42781 atatcgtcgt tgaaagtagt gatttgatct tcgtattttt ctaagatcgc tgcagcattt
    42841 cctcgtccaa aatcttccca atgcaataac aattctggga ataattcggt agctgattga
    42901 acgaattgat cgatgaattc atagtaagtt tcgccttcta cacgagcatg acgattgcct
    42961 aagtataagg gattattcaa taattcttca ttattagtac cagcgtcgat cgatacaggc
    43021 aaaacttgtg ctggattaat accagcagca gcagtataga ccatcaattt gccgatagcg
    43081 atgtcaacac cgttcacacc ccagtcgccc atacctaaga ttccttctgc atcagtcaca
    43141 acaatcaaac gaatgtctcg tccatctgcc gcgttcttca aacttgcttt gatgttttct
    43201 ggttcgtcga ttgaaagaaa tgcagcatct tgcggtttca agaaaatttc gttgtattgt
    43261 tcgattgaat ccgcaacgac aggatcataa acgacaggca tgaattcaac taaatgttcg
    43321 cccatcaatt tataaaacaa tgtccgattc gtattgaata gattcattaa gaagatacgt
    43381 ttttccaaat ctgtttgttt gcttaagtat tgaccataag cttgaacaga ttgttgttcc
    43441 agtgtttgga cagtacttgg aagcatacca gtgattccat attttgcccg ttcttctttt
    43501 gtaaaagctg ttcctttatt tagaaaagga ttatttaata agtttaaccc tgtaagcatg
    43561 aatgattcct cctaagtttt aatacaaacg aagtatagaa gtcagatgat gatatagtca
    43621 aaaagagcag gtatgataaa ttttatttat atgtaatata gccaaaagaa atcaaaatag
    43681 cagtatttgt tctttttata tcgacaatcc ttgcttgaat actatgcgta tctcttatat
    43741 gctagagaaa gaaaagtaga agaataaggg atagatggaa tggataaata ggatttctga
    43801 ggaaaaaagc acatgatagc gttgatagga gtcacctatg tcaggtgata aaaatacata
    43861 agtagaaaat taagaggagg aagagaaaat gaaagaagtt caattgatta gaaaaagcga
    43921 actatcagaa ggcggttgca atgcatgtgg cgtagtagaa gcgacaagct atacattaaa
    43981 attagattcc aatcaagcaa taatctctga actgacagta ggcggtcttg tggacagtct
    44041 ggcgcttgct gaaggtttta ctggagaaga tatttatgag atgttttcag aagtccgtca
    44101 gttaaaaaaa ggagaaaaat gcatagaggt tcatcatgag agcccgaatg tgaggttcaa
    44161 acgtggtgat aatgagatga tcttcaagaa tcatgtgtct gatcacactg aactatatga
    44221 aatcgtgaat caaatactgt ctgggatttt tgaattagga ccttatgagt tcaaggaaga
    44281 aaacggtaat ccaaaattaa atgaagaatg gcaagaaacg attgaaacac aaagaaacaa
    44341 tccacactta tttcaatagt cttccacagt atttcgtaaa aatgttgatg aaaaagaaac
    44401 accgtgaatc agaggtcgtg aaaaacctgc cctgcatcaa gtaataagaa cagccaaaca
    44461 aaaatagctc ctcctatttt tcgtttggtt gggcttatta ccgcagatgc aagtttttga
    44521 acaccgttta aggaagagac tgtgaagtca acgttctgac ctgagtatta gagagacaaa
    44581 tggcaaaata gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt
    44641 gaacaccgtt ttatcgagag gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat
    44701 tttgtgaaaa tggctttcca catttttgca taaatttgac ttaataccga gaaaatggct
    44761 tttgaacacc gtttattcaa aaaaagggac tttgacacta cttttgtcaa agtcccatcg
    44821 gttttttatc tatttttatt acaatcattt cttccagagt agtgacatct ggaatggctg
    44881 aaatgtaaac agattatttg cctgtatcaa tgtcgaagag taatataaaa agtgtaaacg
    44941 ctatcatatt gttcatcatt caaattttat agagagaagg cattgagatg gaaaaaacat
    45001 atcaagcagg tacaaatgaa ggaatagtag attttatcaa tatggaagat ttagaaatcg
    45061 cggcttcaca agtgattcca gctggtggtt atggttacat cagcagtggt gctggcgact
    45121 tatttactta tcaagaaaat gaacgggcat tcaatcatcg tttgattatt cctcatgtat
    45181 taagagatgt agaattaccc gatacaacta cacattttga cgaagaaatg ctgactgcac
    45241 caatcatcat ggcaccagtt gctgctcatg gattagctca tgtgaaggcg gagaaagctt
    45301 ctgcaaaagg tgtagcagat tttgggacga tctatacagc aagttcttac gcttcttgta
    45361 ctttagaaga gataagagaa gcaggcgggg agaaagcacc gcaatggttt caattttata
    45421 tgagcaaaga taatggaatc aatttggata ttcttgaagt ggccaagcgt aatggagcaa
    45481 aagcaatcgt attgacagcg gatgcaacag ttggcggaaa ccgtgaaaca gaccgcagaa
    45541 acgggtttac cttcccgctg ccaatgccga tcgttcaggc ttatcaatca ggagtaggcc
    45601 aaacgatgga tgctgtatat aaatcttcca aacaaaaact tagtccaaaa gatgtagaat
    45661 ttatcgctgc tcattctgat ttgccagtct acgtgaaagg tgttcaatca gaagaagatg
    45721 tctatcgatc attagaatct ggtgctggtg gaatttgggt atctaaccat ggtggccgtc
    45781 aattagatgg ggggcctgct gcgtttgatt cgttgcaata tgtggcagaa gcagtagata
    45841 aacgtgtacc aatcgtgttt gacagcggtg tacgacgtgg acaacatgtt ttcaaagcaa
    45901 tcgcatcagg tgccgatctt gttgctattg gcagacccgt tatttatgga ttgtctttag
    45961 gaggaagtac aggagtccat caagtgtttg atttctttaa aacagaattg gaaatggtca
    46021 tgcaattagc tggaacacaa acagtagaag atatcaaaaa aataaaattg cgtgagaatc
    46081 gttttattta agaaataaat gacgaaaaaa ataggagtgc ggcagatgat gccgtactcc
    46141 tatttttata gttcaaggat gtcactaata gaataatttg aaacgaaaaa ataaaattga
    46201 aatattgttt catacttaat aaaaaaggaa gaatattcat gtaaacgatt ttattgtttt
    46261 tttctctttt atacaaaaag ggtcataatt tcaagtaagc ggatgaattc atgaggattt
    46321 tttgcatact gtctctacta tacttaggtc actaagaaaa aggagtgatt tattatgaaa
    46381 aagaacatga ttgggacatt attactttca acacttcttc taggcggctt ggcaacacca
    46441 gcttttgctg agggtcaagc gacttcaaaa ggagatatta cctttactga accaacaaat
    46501 accgttgagc ctcttaaccc tactgatcct tcaaaaccag tagagccagc agatccggaa
    46561 aatccagcaa ctggccagac aggttcttta acattggatg tagttcctga attgccattt
    46621 ggtacacacg agattgaaag cggaacaaaa acgtatcaag tagacgcttc aaaaaacgat
    46681 acaccttatc tccaagtatc agatcgtcga ggtgtaggtg cagatggcca agcacaaggg
    46741 tggaacgtga cagtttcggt ttcagatttt gtaaacggtt cacaagtttt gcaaggcgct
    46801 gaattagatt ttggaacatc cactgttaaa agtacgtcag ataacgaatc cactggacca
    46861 actagtcaaa ctgtaactgg gttgagtaaa gcaagtgcag cgacaccaat atttacagca
    46921 gcaaaagatc aaggtctggg aacatggctt tctgtttatg atccagcaaa tatcacactg
    46981 aaagtgccga aagcagcagc tggaacattc acggctgatt tgacttggaa cctcgtggct
    47041 ggcccagtag catagagtat gaaataaatt caacaaactg cggtgaaaat actataggtg
    47101 aaggattttt taccgcagtt gttgttgaaa ggatgtggtg gacaatgaat caaagtaaac
    47161 gactgtttgt ttcgtttttt tctattttaa gtctattttt catttttccg tcaatcagcc
    47221 aagcaaagga ttcagcagga gactttggaa tcaaaccggt atttccagag aaccaaatag
    47281 ataaagcaat cggttatttt gatttattag tggcaccgga acaaaatcag acactagaag
    47341 taattatcag caattcttca gatgaagaac gaacatttga ggtctctgtc aatccggcgg
    47401 taacgagtga tggtggaacg atcgattata gtcaaaaaaa cccaacgtta gatgagacat
    47461 tgccgtttga tgtccgtgac gttttgctca ttgcgaaaaa ggaaatcaat gtatcagcac
    47521 atgcagaaac aactatacct atagaagtga aaatcccagc aaaaagcttt aagggacgtg
    47581 tattagcggg tattcatgtt tcacctaaag aagaagctga aacagaaaat gctacagaag
    47641 gagcacaaat caaaaatcgt attgcttata atctcgcagt cgttttacaa gaaagtcaag
    47701 agacgataga accggatctg aaacttttat caggagattt ggacgaggtc aacgcaaagc
    47761 caactgttca gcttcgtttc caaaatcctc agcctaggat tatcagcaat ttgatattta
    47821 cgagcaagat cttttatgaa aatcagcttt atattgaaaa tacgtctaat gaatttttag
    47881 ttgcaccaaa ttcgaatttt cacttgaatc ttgatttagc tggtgataaa gcaaaagccg
    47941 gcgattaccg cgcagaaatc atagcaaaat caggcgacag taatgaatgg cgatttacac
    48001 aaaactttac gatcaaaaaa gaaaaagcac aaaaagtaaa tgaaaattcc gtttttgcag
    48061 tacaagaaca atctttccca tggctttatg caggattggt tgctgcagtt ctagtgttat
    48121 ggttgatttt gctgtttttg tgggtccaca agaaaaagaa aaaaggagaa acaacatgat
    48181 gaggtgattt cgttgaaaac atcgatctta ttgggaggga ttattgcaag tttgctgttc
    48241 ttcagctggc aagagccagt ccaagcagat accaaaagtt caggtacgat tacattttat
    48301 gatctaagtc cagttccgca tccaagtggt tcagtcaatg gcgcatcaaa acagcagaca
    48361 cagctaccga tttataaaga atctaatcaa catggcgtat tcccggagac gaatgaagaa
    48421 aagatccgtt ttctttattt gatcattggt atagaattat ggcttcttgc gtggttgttg
    48481 ttatggagaa gaaaggaaaa ggaggatgaa catgttgcta caaaataaat tttcattttt
    48541 tcgctccttc ttttttactt cgctttttgt tttaagtata tttatctttt caccttcggc
    48601 agaagctgtt ggagcaacgc ctcctgccat ttcttatgat ccatacacgt atgaaaatat
    48661 cgtacctcca aatggtggac gtagtgcagt caatggcggg aagcttgtcc aactaactgg
    48721 ggctaaccaa ttgcctaaat tgactgctac ttatttgaac gatggttcaa atgatccttg
    48781 gaaaggtggc acggtccgtt ttcattggga aagccatgtg aaactaacaa atgtacttga
    48841 tttggtgaat atcactgcac aaggatttgc atttgtggcg atcatcaatt tgccggaaca
    48901 tgtatcaagc agtgatgtat taaaagcaat tgactggaac aacgcctact tgtatattgc
    48961 cggtgccccc atcaaggtta ctagcggtag tttattatca gcaggaagcc ataccttgcg
    49021 ttttgggatg gggtcgtggg atacaaatac tctattggca gatattattg ctattattac
    49081 gcgaggtatc ccgcttcaat ttgatgttac agctaatgtc gcgaagatga cagaaaacgg
    49141 agataaatat gatacgagtc caaacaaaat tttgaccaag ggtaaattac aaccttctat
    49201 gtctaaaaag gccgtttttt ctgttgattt ttatgattcg aataatatta tccaagatcg
    49261 tatgttcaat tcgattttag ctccagctgc aggtagattt tatcctaaat taactggcgg
    49321 aaacttgaat ccaggagcat atgcattttc tgcaagtgca gagataaata cgtggaatag
    49381 ttacatctca acaagtgatt caacaggaaa atataataca tttgctgata ccacagaata
    49441 cgtggatgga aataaccaga accttccagg ctctaccaat agtcggacat tgacgatggg
    49501 gctgactgaa ggacgttttg atcagttgcc atttagtcgc tttgatcgcg tagtcaacta
    49561 ttttacagga aaaaacgtta cacaaggagc aatactgact catactccag caagcacaag
    49621 tggattgaat cagacagcca atatcgtgta cagtgggaaa gatgcgcaag gcggattgct
    49681 ttctcctgtt gctttaaagg tattggagca gtacaagcta gacggaacgg ttttaccaac
    49741 aaacttaaca gccgatagtc agtggggaaa gctcctttct tctgcatcgt accaagtcac
    49801 ggccaattgg tcagcaactg aactaaaaaa gggttcgatc cattacaggc tttattcgaa
    49861 aggaacccaa aaattagcga caggatggac agatcaactt ttccaaacga tccaatcaaa
    49921 taacgggggt gtaaatacag ctacttctac actacctgca ttggcttcag ggcaatatta
    49981 ttttgattat cgcttggtgg acgatgtact tactaacatg tatccgtctt ttgcgtacaa
    50041 atggcagtct gaacaagctg gaatcaccac tcttcctcaa ataacagtgg ctaattttcc
    50101 atctgtgagt gcagatagtc agctaaaaaa ccttagcaga caacctgaga caggagatcc
    50161 cctgtctgct ctatcaggag atacgattca agaaaatgtg acattcacgt taacaaaatc
    50221 tggggatgcg ataaccgaca aaaaaatcac gatctcactt cctgaaaata ctacttatat
    50281 caatggttcc ttaaaattaa atggtacaac tatcgcagat accggcattc aacaaggagt
    50341 ttctgtccca gcagatctat tgagcaaaat aggagatacc attcatctta cttacaacta
    50401 tcaattaaat actgtagata cttctgtaca atccgtcagc atactgacaa aggcagctgt
    50461 actttccagc aatattacat tagcagatgg tgctaagctt cctaacccag ttgtccaaac
    50521 atctgctaaa acaattcttg tccccaaaca agaattaaca ttagttaatg taccagatga
    50581 ttttacattt ggtaacgatc tccccaaacc gttgaagaca agttattatg aagcaaaagg
    50641 cgatttttct tttgatgtgc gggatactcg gcttccaagc acgtctcctt ggcaactgac
    50701 agggacattg acttctttat ttaagaatga tcaaggtcaa gaattaagcg gaacaaaatt
    50761 atacttcaat cattctggat caaaacaatt gattcagcaa ggtcaaaaca cgttgattta
    50821 tgagagtgat ggaacagcta aaggagaggt tctcgttgac tttcccgata ccgatggttt
    50881 actcttagag gtaaatagca gtacgaatgc tcaacctggc gcaacgtatc aaggcatggt
    50941 cacatgggaa ctgacagctg ggccaaccag ctaagtgatt agaatttgta tggatctgtg
    51001 ataactgtca cagatcctct ttttcaagga tgagaaggaa acttctgctg ttaaaatcag
    51061 aaatgcttgg aggagtggac ttggaacttt tcagtttgct tgaaaaaaat gaacaacggc
    51121 aaatcaaact tttccaactt ttattagagg aaaaaggaga gatttccgtt aataacgtac
    51181 ttacccgctt atcagttgat cgggctacct tgaaagaaga tctgttttat ttacaagcta
    51241 acttggaaaa tatcaaacaa ttggaaattg ttatccaaga agggaatatt ttattaatca
    51301 gacatggaaa tatagcagca gtcgatgttt attatcattg ctacttgcgc tattctacaa
    51361 aatatcagat acttctttat ctgttggaaa atggctcatt tgatcggcag aaacttgtca
    51421 tggaacttaa tatcagttcg gctactttgt ctcgcagagt gaaggaatta aatgattctt
    51481 taaatgagtt tcatctgaaa ataaaaagcg ggcggctgac cggtccagaa agtcaaattt
    51541 gttattttta tttccaatta ttttggtttg gacgtcctta tcttgaaaac aaaaaagaat
    51601 acagtgattt atcaggaaac acttttttag atctgctgca aaaagagttt agttttacta
    51661 ttacagaaga aggacgattg aaatttgaaa tatggctttc cattatgaag aagcgaatgc
    51721 gctgtacgaa aaaatccaaa ccagattata gcaatcttcc tgttggattg tttcaaacga
    51781 cacaattttt attggacctc catacatttt tgacccgtta cttctttcaa tatgcctttc
    51841 cttggaatca aaatgaaacg ttggtttttt atcttttcat gatcagtaac tttacattag
    51901 atacacataa ctcgcatgtc caggagtttt tgataagcga aaaatacaaa gacgacgtag
    51961 tagctcaatt gaatcgaacg tttaaacaat cgatagaaga atatttctct ttttatgttt
    52021 ttccagaaga gatttcgcaa aagattgcgt tgacagtgat gcaaaatcac gctcattttg
    52081 cctattttag aggatggatg aatatttttg gccaagaagg attaaaacag cggttaactg
    52141 aagtagaaga taaacaattc ctggttttat gtgaaagatt ggtcagacaa acatttgcta
    52201 ttgttgattt tactgaagta gacgaggaaa atgcccgctt tgaattattt gctcgctatg
    52261 catctatttt gcggacgctg atcaagcagt tagaattacg tctgcaaatt gcttatgatc
    52321 ttccttatga aaggctaatg gcggatatcg tgaaagaaat catccaggaa caattgctga
    52381 atacgatcaa atatgattta gtcgaatacg agaaagaaaa gcagtatgat atcattttga
    52441 ctagccaatt gaaagagtac ccgtcacaga agtccgctaa agtttttgta ttcactagca
    52501 acgaatataa ttatgatttc ccctatttga accaattttt aaaagaatgt tatttagaaa
    52561 aattgaattt aaggatgaat aaaacatgaa aatcgtgatc attggtgctt cccatgcagg
    52621 catcacagct gccctaaatc taagaaaact tcaaccgaaa gcagaagttt tactgatcga
    52681 tgaagatcat aaagatggac taggctatgt ttcaaatgga atcaaccttt atttaaaagg
    52741 aaagatacgt agtttagctg aagttgccca taacatgcgg actcttcaag aaagtggggc
    52801 aaaactgatc accgaatgga gagtaactga acttgatcca gacaaacatc agctcatcct
    52861 cgcatccaaa gaaggaaaaa acgagaccat aacctatgat aaattaatcg tagcaacagg
    52921 ttcctctcct gtcaccttgt ataaacaaat tgaagctgaa aatgtctaca cctataaaaa
    52981 tctagtgcaa tctaagcaag tacttgccgc tttaaaagaa gcaaaagaag tagtgatctt
    53041 cggtgctggt tatattggat tggaattagc agatgctttg agaaataaag gatacattat
    53101 tcatctagtt gattatatgc cgaatgtttt atcaagatat ttcgataagg atatgatcaa
    53161 cagttttcaa aatcagctgc aaactaagca aatcaatttt tatccaaatg aattcttgat
    53221 cgattggaaa aaatcagaag agaaagtagt atccgtacaa cttctatctc aagcaataaa
    53281 ggcagatatg gtcatttttt ctgcccaaac tcgtcctaat acgacattgt taaaagaaaa
    53341 agtggctttg tatgaggatg agactgtgat agtcaatgaa tatctgcaga caagtgatcc
    53401 ggacatctat gcgattggag atatcgtccc agtcagtttt gacaaaaata aacggcatct
    53461 ctttttacct ttagttactc gagctgtaca tatggcaaga gcagtagcgc taactttgag
    53521 tggtcagcca accgcttacg acctcagaca aaagataaca gcagcagtca ttatagacta
    53581 ctttttagga actgtagggc tgacagaaga tgaagcgcca ttcttggaac aaaataccgg
    53641 ttcgtgttca ggagaatttg atctatttcc acaatacgat gaagaaaaca aaacagtaaa
    53701 tgcaaagctg atctaccatc cggatacatt agaaataatt ggcggacagc tgataagcca
    53761 agaattctta ttatcagatt tgaacctgct tgcggatatc gtgaaacaca aaactacgat
    53821 tccacagcta gcagttgagg attttggatt tctgtctgaa cacacctctc gttttcacta
    53881 cctcaatgag ttagctttta aagtactagc taagagagca aatagcaata gagtagataa
    53941 aagactgtga gaaatatcac ggtcttttat tgtgtgggga tataataaat attaatcaat
    54001 cgagaataaa aaattcatat aatgaaatag cggaagaatt ttttgagcat aatattcgcc
    54061 aaaaatttat caagtgataa aattgttgta taaaatgatt atttcaggag gaggagttaa
    54121 atgtttttag cattaaatga aattatgcat tcaaagttac gttatgcgtt agttgcaggg
    54181 gtgatgtttt tgatcgccta cctggtattt tttttgactg ggttagctta tggcttagct
    54241 caagataatc gaacagcagt cgacaagtgg gaggcagatt cgattgtgct ttcgaaagat
    54301 gcaaattcaa atctagggat gtccatgatt actaagaaga tagcagaaga agtcgaaggt
    54361 gggaaagtgg cgtatcttgc ccagacacct ggagtcgtga ctagtaaaga cagtacagaa
    54421 gaaggaaaaa tcaatgttag cttcttcggt atcgataaaa atcaattcat catgcccaat
    54481 cttgttgaag gaaaagcttt tgataacgat gatgaggcag taggcgatat tagtttgaaa
    54541 gaagaatatg gtctagccgt aggagataca gttaagttat ctggtagtga caagacgttt
    54601 aaactaactg gctttacgga tcatgccaaa ttcaatgtct caccagttct ctatacaacc
    54661 atcaatgctt accaagagat ccgcttcgaa aaagaagata caagtgaaaa tgcacggatt
    54721 aacgcaatag ttgtcagagg taaaatcagt aatttacctg aagatttaga acagatcaaa
    54781 atttctaaat tcatcaatga attacctgga tataatgcgc aagtattgac ttttggattt
    54841 atgatcggat ttttgatcgt tattgcggct attgtgatcg ggattttcat ttatgtactg
    54901 acgatgcaaa agattaatat ctttggtgta atgaaagcac aagggatcac aggaggattt
    54961 attgcgcgtt ctgtagtggc acaaacattc attttatcat ttgttggtat tcttcttggt
    55021 ctattaggaa cagtgggaac atcccttgtt ctacctgatg cggttccatt ccaaagcaat
    55081 tggctgtttt ttggcgtcat tagcttgttg atgctggtag tagctgtgtt aggcgcacta
    55141 ttttctgttc ggacaatcgt aaaaatcgat ccgttgaagg caattggata agaaggagga
    55201 agagcatgaa agcaatagaa tttaaagaag tagaaaaaag tttccaagat ggcgaccaag
    55261 tagttaaagc attgaaagaa acaaccatga gtatcgataa aggggaattt gttgcaatca
    55321 tcggtccttc tggttcaggt aaaagtactt ttttgacttt ggcaggcgga ttgcagacgc
    55381 ctagcagtgg ctctgtattt atcaatgatc aagaattcag taatcaaaaa gaaagtgaac
    55441 gcgttaaact acgttttaaa gaaattggct ttattttgca agcttccaat ctggttcctt
    55501 ttctgacagt aaaaaagcag ttattattag tagataagat caaacatgaa catcgtcaaa
    55561 aagaagcaaa agaattattt gagcagcttg gcgtggataa gttgatcaac aagtatccag
    55621 aagaactatc tggtggagaa cggcaaaggg tcgcaatcgc tcgtgcattg tacaatgatc
    55681 cgtccattat tctagcagat gaaccaactg ctagtttgga ttcagaaaag gcacgagaag
    55741 tagtcgatat cttggcaaaa gaatcaaaag acaaaaataa agcaacgatc atggttactc
    55801 acgatacacg gctgattgac aaatgcgata gaatatttat gatggaagat ggtgtattga
    55861 aagaaaaaga ataaccaaaa agcaggtgga aaaatggtcc atcgatacaa caaagataca
    55921 cagcaaaaaa ttttgaaaga agcgactgac ttgtttatgt ccaagggata tctcggcact
    55981 tcaacaagag agatcgcaca aaaagttggg atcacccaac ccaatctcta tcattatttc
    56041 ggtgataaag aaaaactata tacggcagtt ttagaaaacc acttaaaaga tgttggaaaa
    56101 gctttgagag aaatcgttca aacaagcgaa acgggatttc aagtaacctt gacaaaaatg
    56161 gcgcagtttt tgattgagac acatctggtc gatttgtttc tgatgcttca cgatcttgaa
    56221 agcaatcttt caaaggaaac aagagatcat cttttctttc tatggaagaa aaattatcgt
    56281 gaaccttttg aagaaatctt ttcagcaaac caatctgtgc taagaaatgg gatttcaaaa
    56341 gaaatcgcag caaggcattt tttcttagtg ttagcacctt acatcactcg gtcgaaaaga
    56401 cctgtggaag aaccgctaaa tgtggcgcaa ttgatcgatt tatatttgaa tggtgtatta
    56461 ggagaagcgt aaagctgtta tatagggaga aaaatagtta ggtgaagaag caagatatga
    56521 cgaagatcgt tatatcttgt tttttttata taggtagttt ttcataaata caaatttgtt
    56581 attctctcat gattatcagg gtatattttt atttattatg tcggtgttcc aggaagtgtt
    56641 ttaatttaat aacgaagaaa ttaattgttt gtagaatgaa ggaaactatt tattgggtag
    56701 atgaatcacc acgaatagtc aaaaggagat ttcaggatat gccaaaaatg aaaaaaatca
    56761 ttttagcagt aatgttattt tctacggtta tatcttttac agcccctttt ttgcgtactt
    56821 aagctgattt taagttttga cccttagtct ggatctacga ggtgagagtc aagaatgaaa
    56881 aaaataattg gagcttttgt atttgcaatc attatcatta ttatctgttt tcaaatagat
    56941 gtttttggtc aaaaaaagat agttggacaa acggtcagca gtacgaacag tacggttaca
    57001 aagacaaagg aatcatttga tgatacagaa caagagacat taatcaaaat cggaaaaaat
    57061 gaccgtacac tatatacaga tgactcgcta actaccccac ttgcaactat aaacggcgga
    57121 gagctggcgg agtttctttc tgaaacaaaa aatgcttatc agatcaagac aaatgatggc
    57181 tatactggat atttagccct cgaagatgga accaaagtca caaagaatat acaaacaaaa
    57241 ccggaagagc tatctgatgc agtgattgta ttagatcctg ggcatggcgg aaatgatact
    57301 ggggcattaa gcaatgatga acaaacagaa gaaaaagata taacattaag tacagccata
    57361 aaagtaaaaa aggcgctaga ggatgctgga gcaacggttt atttgaccca tactacagat
    57421 gaattagtac agcttggaga tatatgcgac tacagtgaag aaaaaaaggc agatgtcttt
    57481 atcagtttac acgcagactc tacggaatat gcgaatgaag caactggaat cacgacatat
    57541 tattactatg gacaagagga aacattagca cagacaattg ctgactcctt cactgatctg
    57601 cctctggatt caagaggaat ctccactggg aactatcaag ttcttcgaga aaatcttcaa
    57661 ccttctattt taatcgagat gggttatatg aataatgata gtgatttaaa ggaattagta
    57721 acagacagtt atcagcagca gattgctgca agtttgacac aagcattgac cacttatttt
    57781 cagtaataaa taagcccagc caaacaaaaa tagctcctca tatttttcgt ttggccgggc
    57841 ttattatcgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg agcctgccgt
    57901 ttaactccgc gtcacaagga gcaatttcaa aaaacagctt ctcatgtttg atgactattg
    57961 tgacttgtga ccgaggagtt ggcatgagaa caccgtttat tcggaacaag ggactgtgac
    58021 atgacttttg tcacagttcc attatttttt tagcagcttc aaagcttttt ctgtattggc
    58081 aaaatgaagt ttggcatatt tttcaagcat aggcatgccg cctttctcca atagttttgc
    58141 cgctacttgg tcagatttcg ttccagctcc tgatggaagg gtgattccag cttcagctga
    58201 tgctttgtgt aactcttcca aaaagctggc acgactgatg atagaagcag cagcaacagc
    58261 taaatgatat tgttctcctt tagtaacgaa gtacagtttt tcttgtaatt gatttttttc
    58321 taaacgcgca tattttttaa aatttgcttc cggcgtaaac tgatcgatca aaatcgcttc
    58381 tggtttttct ggctcgattt tttttagcag caaatggatc gcttgattgt gcaaagcgac
    58441 tttcatccga acggcattgt attttggttg gatctcattg tatttttctg gagataagac
    58501 aagcagttta taggggatgg ttttttttaa gatgtcagca agctggatga tttggctatc
    58561 ttttaactct tttgaatctc taacaccaag tttacgtaat tctgcaagct gatcacgttt
    58621 cacataagca gcacatactg ttagcggacc aaaatagctg ccatttccga cctcatcact
    58681 acctaaaacg gataattgac tgatattttt tgtttttgct ggcttggctt gtttatcctg
    58741 tgcctccccc catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc
    58801 ggatgtataa gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat
    58861 ctgtttattt aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt
    58921 tgctttgata atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg
    58981 caactcacga cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat
    59041 catataatag ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat
    59101 ggtacactaa ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa
    59161 acacgctaca aagcagtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag
    59221 catcatatgg atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta
    59281 tcaccacaaa tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat
    59341 caattgaaga aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa
    59401 aaaatgatca aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac
    59461 gaagctcggg aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg
    59521 gaagcacaac agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat
    59581 taagatcctt ttatcaaaat aagaaaaatt taaaaaagtt agaagagaaa ggaacgtagc
    59641 atgctgagtt tgctgatttt atttttattg ctaattgcgt ttttttctgg agcacgtcgc
    59701 gggtttgctt tgcaaatcat attcgcgatt ggatatgtat tgtcatttat tgctgcccag
    59761 catttttaca aaccattagc aagtcatttg gaattataca ttccataccc agctgtcacc
    59821 ccaacatcaa agttagcatt ttttgatcag gtatttgctt ttcacctaga tgaagctttt
    59881 tatgcaggaa ctgcttttct gattattttg ctaattggct ggctgcttac ccgatttgtg
    59941 ggggtttttg tccatggatt gacgtatgtg ccgatcttga gacaggtaga ctggattgca
    60001 ggaggcatcc tgtcactaat catggcttac gttactatat ttttgatttt gcagttactt
    60061 gcctttgttc cattagatgt ggtccaaaat caattcggcg agcatagttt cgctcgtttt
    60121 atcgttgaga gaacgccatt tcttaccaac aagatgtatg agctttgggt aacgaatatt
    60181 ttgaattaag gaaaatagtg ctggaaaata tttcgttttt tgtacagagt agtttattta
    60241 agaaggctgc gtagcgtatg tccggcacag ctcttttttc atagtgaaag ataaggtgat
    60301 aaaatgaata accgaatcct tgaaacattg gaatttgaaa aagtcaaaca gatggtcaga
    60361 caatttgtag tgactgcaca aggaaaagaa gaactggcag aattggtacc agtgagtgag
    60421 aaacaaacga tcacaaactg gcttcaagaa actgaggatg gattgaaagt gcaacgtctg
    60481 cgaggcggga tccctatacc taaacttgaa aatatccgtc cccatatgaa acggatcgag
    60541 atcggagcag acttgaatgg agtggagctt gcacaagttt ccagagtatt gtctacgaca
    60601 agcgaattga atcgtttcat tgatgatctt tctgacagtg aaatcgaatt tgcacgtttg
    60661 tatatgtggg cagatcagtt agtcacgatc cctgttttga gccgccgttt aaaggaagca
    60721 atcgatgaag acggacgcgt gactgatgac gcttctcctg agttaaagag cataagacag
    60781 aacattcggc gaagtgaaca agctgttcgt gaacagttag atgggatcgt ccgtgggaaa
    60841 aatgcaaagt atttaagtga tgcgatcatc accatgcgaa atgaccgcta cgttatccca
    60901 gtcaaacaag aataccgcgg tgtatttggc ggtgtagtcc acgatcaaag tgcttcagga
    60961 cagactttat ttattgaacc aaaacaagtg gtggatttga ataatcgttt gcgtcaatac
    61021 caaatcgctg aacgaaatga gattcaacgt attttaagtg aactttctgc tgaacttgtt
    61081 ccccatcgtc aagaaatcat ccacaatgct tatgtgattg gtaaaatgga tctgatgaat
    61141 gcaaaagcac gatttggtaa agaagtaaaa gccatcgtgc cgggaatcag tgaagacaat
    61201 catgtcgtct tgaaacaagc aagacatcca ctgatcgatc aggaaaaagt agtttctaat
    61261 gacatcacaa tcggaaaaga ctatcaagcc atcgtcatta caggacctaa cacaggtggg
    61321 aaaacgatca cgttgaagac tttaggtctg ttacaactga tggggcaagc aggattaccg
    61381 attcctgcag gtgaagaaag tcaaatcggt atttttgagg aagtatttgc ggatatagga
    61441 gacgaacagt cgattgagca aagtctatcg accttttctt ctcatatgac gaacactgta
    61501 gatattttat caaaagtcaa tgaaaaaagt ctggtattat ttgacgagct cggtgcagga
    61561 acagatccgc aagaaggtgc tgctctagca atcgcaatct tagatgatct tggtaaaaag
    61621 tctgcttatg tgatggcaac aacgcattat cctgaattga aagtttatgg atacaatcgg
    61681 gcaaatacga ttaatgccag catggagttc gatgtggata cactaagtcc aacgtatcgt
    61741 ttgctgattg gcgttcctgg acgaagcaat gcgtttgaaa tctctagccg attaggtctt
    61801 gatacagaag ttattgatga agcgaagcag ttgatgaatg atgagagcca agatttaaac
    61861 gaaatgatca cagatttaga gaatcgccgg aaaatggcag agaccgaata tctggaaatg
    61921 cgtcattttg tttctgaggc acaagaactt cacgatgatt tgaaagaagc ttacagctat
    61981 ttctttgaag aacgtgaaaa agaaatggaa aaagcaaaga aaaaagcaaa cgaagtcgtg
    62041 tcagaggcgg aagaaaaagc agaaaaaatc attgctgata ttcgtaaaat gcaacagcag
    62101 attgggcaag gaaatgtgaa agagcatcag ttgatcgatg caaagaccca attagcaaat
    62161 ctacatcaag aagaaacttt gaagaaaaat aaagtattga agaaggcgaa agaacaaaaa
    62221 acgttgaaac cgggagacga agtgttggtt acgacttacg gccaaagagg gacgctttta
    62281 cgtaaaaacg ggaatcagtg gcaagtagaa atcggtatat taaaaatgaa tgtgtccgaa
    62341 gacgagctga cgcctgttgc tcctcaaaaa gagccgacac aacgagttat ccatgctgta
    62401 cgatctgaat ctagtagtca cgtgccgaat caattggacc ttcgaggaaa acgatacgaa
    62461 gaagcgctaa gtgaggtaga tcaatatttg gattctgcca ttctagctgg ttatcctcaa
    62521 gtgactattg tccacggaaa aggaacaggc gcacttcgca agggaattac tgattatctt
    62581 aaaaaccatc ggagcgtcaa aagctttgag tttgcaccgg caaaccaagg cggaaatggt
    62641 gcgacaattg ttaaatttaa gtaaagctta ctaaaggtaa gcagatggtt cgctatccaa
    62701 gtatagaaat gctatactaa tcatagattt taaaaatgga ggtctttgat atgtcacaag
    62761 taattacaga taagacattt aatgaagaaa cagataaagg acttgtattg attgattttt
    62821 gggcaacttg gtgtggtcca tgtcgtatgc aagcaccgat tttggatcag ttggaacaag
    62881 aatatgatga agaagaattc agaattgcta aaatggatgt ggatgaaaat ccagaaactc
    62941 ctcaacaatt cggtatcatg agcattccaa cattaatgtt gaaaaaagat ggtcaagtag
    63001 tagaaaaagc tgttggtgtt cattcaaaag aacaactacg tcaaatgatc gatcaatatt
    63061 tataaaaact tacagcaaaa ataagctgag ggtgggactg aatccagttc cgtcctcggt
    63121 ttttttgcgg ttgagttaag gttattcaaa ttaatatttt ttgagtataa ttacgttgtc
    63181 aggctggatt gtttttttga cagacatgct ataataactt taattgaata tgaaggggag
    63241 taccagatga acgaacgaat caaaaacaaa ttagctttac ttcctgatca gcccggctgt
    63301 tacttgatga aagataaaaa tggaacgatc atttatgtcg gcaaagccaa aatattaaaa
    63361 aatcgtgtcc gctcatattt tactggcagc cataatacga aaacggaacg gcttgttagt
    63421 gaaatcgaag actttgaata catcgttaca gaatcgaata tcgaagcatt gctcttagag
    63481 atcaatctga taaagaaaaa tgatcctaaa tacaacatta tgttaaagga tgataaaacc
    63541 tatcctttcc ttaagataac gaatgaaaaa tatccccgtt tggtgattac tcgtaaagta
    63601 ctaaaagaca aagcactgta ttttggacca tatcccgatg tcggtgcggc gaatgagaca
    63661 aagaagatcc tcgatcgatt atttcctctg agaaaatgca aacctagtca gacgaaggag
    63721 ccttgtcttt actatcattt gggacaatgt ctgtgtcctt attatttcga cgtagatccg
    63781 aaagtctata cgaaaatcgt tgatgaagtg aaaaagtttt taaacggagg acacgaaaaa
    63841 atcgagtcag agatccatca gaaaatggaa aaagctgctg aaaacatgga gtttgaaaaa
    63901 gctgcagaat accgagacca gatccgtgcc attgagacaa tcatgactcg ccaaaaaatg
    63961 acaaatactg atttactgga tcgagatgta tttggttatg cgattgacaa aggatggatg
    64021 tgtgtccaag tgtttttcgt aagacaagga aagctaattg aacgagatgt ttcaatgttt
    64081 cctttctata acgaagcaga agaagatttc ttgacttacc tcggtcagtt ttatcaggaa
    64141 aatgagcatt tcattcctaa agaagtcttg attcctgata cgatcgacaa gcccagtgta
    64201 gaagctttgt tagctacgaa agtgctgcaa ccaaaacgag gagaaaagaa aaaattagtt
    64261 gaattggcga ataagaatgc ctcagttgct ttgaatgaac ggtttgatct gattgccaga
    64321 aaacaggaac ggacgatcgg agcagttgaa cgtttaggaa acgcgatgaa tatcccgacc
    64381 ccaatacgta tcgagtcttt tgataactct aatatcatgg ggacgaatcc tgtggctgcg
    64441 atggtcgtat tcattgatgg aaaaccggca agaaaagaat atcggaaata taaaataaaa
    64501 acagtcaacg gaccggatga ttatgcatca atgagagaag tcatctatcg cagatattca
    64561 cgagtgattc gcgaagggtt gcctttacct gatttgatct tgatcgatgg aggaaaagga
    64621 caagtagatg tggcaaaaga tgtcttagaa aatcaattag gaatcgatat tcctattgct
    64681 ggcatggcaa aaaacgataa acataaaaca aatgagttgc tattcggtat agatttggct
    64741 gtagtaccgc ttgagcgaaa ttcaccagag tttttcttac tccagcgaat ccaagatgaa
    64801 gtccatcgat tcgcaatcac tttccatcgg cagctacgca gtaaaaacag ttttgcttcc
    64861 cgattagatg aaattgaagg gttaggacca aaacgaaaaa aaatgctgct taaagagttc
    64921 aaatcgttga aaaatatcac agcagccacg acagaagaat tacaagaaat cggactgccg
    64981 aaaaatgtcg cacaaaacgt atttgataaa ttacatcagg aatgaggaaa gggcacttta
    65041 caaagaaagt aaagtgtcct atcattttat gtacaacaaa aagagcgttt acgttttgtt
    65101 ggtaaataat aaatcgctta cgtctggtgt ctaaggatat atgtgatttc ttgaagaagg
    65161 agtgaagaaa tgttagaagt caaggatctt gttaaaactt ttgggaacta cacagctgtc
    65221 gatcatgtct ctttccaaat ccccgatgga aaaatcatgg ggctaattgg ccaaaacggg
    65281 gctgggaaga caacgacttt tcgtttgatc ttggattttt tgacacaaga ccaaggagaa
    65341 gtgttatgga atggccatca tcttggggag aaagattatg atgtcatcgg ttatcttccg
    65401 gaggaacggg gactttatcc gaaagtaacg attcaagacc aactgcttta ttttgcagaa
    65461 cttagaggga aatcaagaaa agagattgaa ccaaaaatcg atttttggat ggaaaaattt
    65521 caggtaaaag ggaaaaagac ggataaagta aaatctttgt ctaaaggaaa tcagcaaaaa
    65581 gtccagctga tcgccacgtt aatccatgaa cctaaattga tcattttgga tgagccattc
    65641 agcgggttag atccggtaaa tgctgaattg ctaaaagatg gaatattgga attgaaaaaa
    65701 catggttcat gtgtcatttt ttctagccac aatatggata atgtagaaaa aatctgcgat
    65761 catttgatca tgttgcgaaa cggaaaaatg gttttgaatg gaaaagtaca tgagattcgt
    65821 gaatcatttg gccgtacgaa gttattcttg gaatctggtt taagccaaca ggaagtagaa
    65881 gaaatcgaag gcgtgaaaaa agtgatcctt catgaagaca atacgttaga gattacctta
    65941 gaagatcctg aagctgggaa agaaatcttt actcgtgcga ctcagttcgg ctacattcct
    66001 atgtttaacc agcaaccgcc aactttggaa gagattttca aattgaaagc aggtgaaatc
    66061 gatgcgtaag ttttggatta ttaccaaaga tgtctattta aaaaatgtta agtcgatttc
    66121 tttcttgatc atgatattag tcccttttat catgctgggt atcatttatg tagcaggaaa
    66181 ctttgctcaa caaaatagtg atgtcaataa aatcggcgta ttggctgata atgagcaaat
    66241 cagtcagcaa atgagccaag tcaaaacaga tgattttgag ttcaaagcag ttgattctga
    66301 agaaaaagca caaaaagagc tttcggaaga aaaaatcgat gcgtatttag tagtctcaac
    66361 tgagaatgat aagataaatg ggatgcttta tagcgaaaat tcattaggac aaagtacaca
    66421 actactgata caacaacaac tgactggctt gcaatcgatg cttcgagcaa gtcaattagg
    66481 catttcacca gaagaagtag ctagcttgag ccaacaagca agtttgactc gacaaaaagt
    66541 caattttgat tcaaaaggaa aaatgacagt tggagaagat aactcgacag tccaatatgt
    66601 cgtaagttat gtagcaacga ttgtcttgtt cattattatt ttgacgtatg cgcagatcat
    66661 tgcacaagag atcgcttctg aaaaaggcac gcggatcatg gaagtgatcc tgtccagtac
    66721 gactgcacaa aagcattttt acggaaaact aacaggtgtt ttacttgttg cattaacgca
    66781 aatggcatta tacggtatta tttttggtat aggatacagt caattcaaag atatggaaat
    66841 ggtcaaaaat atattagacg gtatctcatt ggataacttg attggaccat tcttgtggta
    66901 ttctcttcta ttcatgatct ttggcatttt gattttttct gttttagcag ctttatgtgg
    66961 ctctttggtc aacaaagcag aagatacagc aaaagcaatt ttgccagtga cttatctatc
    67021 tctaggcgga tatatgcttg gattgatact aggagcttca gatccaaaca atatcgttat
    67081 tcggatcact tcgtatattc cattcttatc ttcatatatt atgccggttc gcttagcaaa
    67141 tgagacagtc ggtatgggtg gagcattgat ttccttgttg gtacttgtag ccgtaacatt
    67201 cttattgatg atcttgtctg caaacatgta caaatcgaat gtactcgtgt atagcgaagg
    67261 cggattatgg agttcattga aacaatcgat ttcaattatg agaaatgaac gaaaaaaagc
    67321 ataaaatata gaaaaatata gaaggaagct ggacatttat tgttcccagc ttcttttttg
    67381 tatagaccta tttctatttt tttattatat tggatatata ttcattgaaa atagagcata
    67441 acaactttat aatgttgagt ataccaattt ttggaggcgt tttaatggac cgctatttag
    67501 atttactttc agagaagttc cctacaacgg aagatgtcat cacggaaatc atcaatctcg
    67561 aagcaatttt gcagcttcca aaaggaacag agttattttt gagcgatata catggcgaat
    67621 ttcctgcttt tgatcatatt ctgcgtatcg gttcaggaaa tcttaaagaa aagatcaaag
    67681 accttttctc tgaacaaatg acggaaacgg agatcagcca attcactatt tttacggctt
    67741 atccagaata tgtgttgacg actgattggt acaaaaaaca agataaatcc cagctgatcc
    67801 atcgtttgat cgatctttta cggtttacga cagtcaaata cactcgatca aaagttcgaa
    67861 aaggattgcc gaaagaatat agctatatca ttgaggaact cttgtatatc gatgatcgta
    67921 tcaacgggaa aaaagactat gtaaaaaaaa tcattgaaca acttgtcttg atgaaggaag
    67981 aagaaaaatt tttaacaaaa cttgcgcaga cgatccaaaa atctgtcatc gatcatttgc
    68041 atatcgtggg tgatattttt gatcgaggaa ctcaagcagc caaagtaatg gatcgaatca
    68101 tggatttttc ctctgtagat atccagtggg ggaatcatga tattttgtgg attggtgcgt
    68161 attgcggctc tgaggcatgt ttattgacgc ttttacggat tgccgcacgc tacaactatt
    68221 tatttgaatt agagaaagaa tatggattaa atttacgtcc attattttct tttgcccatc
    68281 aaacctatca gaagaatcca gtatttaccc ctaaaaacag gaaagatcta tctgaaagag
    68341 agcaagaaga attagaaaag atccatcaag cactttctat cctccaattc aaatcagaac
    68401 atcagttgtt gaatcgacga cctgaattta aaatggacga tcgtaaattg ttggaaaaaa
    68461 tcaactatga ggaatcaacg atcgttttag aaggtcagct ctatgagttg aaagggactt
    68521 gttttcaaac gatccagcca gatgatccta aaaaattctt ggaagaggaa caaaaagtga
    68581 tcgatagttt gatgtattca ttccagcact cgttaagaat gcaaaaacac atgacgtttt
    68641 tgatcgaaaa agggggaatg tatctcacga acaatcagca tgtactgttc catggctgta
    68701 tacctgtaga tgaaaagggg cagctcttag catttgaatt agaccaatct tatcgcggaa
    68761 aagaactgct gggatttttt gaaaaacaga taactgaaag cgcaaaagat ttgactgcaa
    68821 atgaagattt ggcgaccgat ttgatttggt atgcgtggag cgggccattt tcgcctttat
    68881 tcggcaagag taaaatggca acttttgagc gctattttct cacagagcct catacgcacg
    68941 tcgaaaaaag caatccctat tatcacttgc gagatgaaga gtggttcagt gaaaaaattt
    69001 tggcagaatt cgatgcaaaa gaagaaggtt cagcaatcat caatggacac acgccagtaa
    69061 aagtaaaaaa aggagagtca ccgatcaaag caaacggaaa agcatttgtt attgacggag
    69121 gtctatccaa agcttatcaa aaaacaaccg ggattgctgg ctactcatta ctatgcaatt
    69181 cttacggttt ccaaatcgtg acacattatc cgttcttgcc tattgaacaa caatttgcaa
    69241 aaaaatctga tcaaacgaat gtaaaaaaag tgatcgagca gcagctccca cgcaaactta
    69301 atcggaatac gacaaaagga atggaattac agcaacagat tactcaactc caaaggctgt
    69361 tggattatcg aaaggacgat tgagaaaaat gctagccaac attgctcaat agactaaaaa
    69421 gcgactgcaa caaaaggcgt gtcgcagtct ccttcggaat tagctcaaaa aacggtaaaa
    69481 tattagaagc tatttttctg tttatttctc taatactcag gtcagggcgc tgatttcacg
    69541 acctcttcct taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatccaac
    69601 aaacatgaga agctgttttt tgaaattgct ccttgtgact cagagttgaa cggcaggctc
    69661 acgacctaat cagaaaaacg attaaaattc attcacaaag aaatcgaata aacgctgttc
    69721 agatgaatct acacgatgag aaagttccgg atgccattgg acaccaagga ttttgtgcat
    69781 attatcttta ctttggactg cttcaatgag tccatcgttg gaaaaggcga tggcttttaa
    69841 caaaggagaa agatctttga ctgcctgatg atgataggaa ttcacaaagt atgaatcagg
    69901 gagaaggtca cttaataaac tgtccgaaac gattttgact tcgtgagttg caaactgcgg
    69961 ggcagtgggc tgttgttcgt gttttacgga ccattttgga tataatgaaa gatcttgata
    70021 aagtgttccc tccaacacga cattcaatag ttgaagtcct cggcagactg caaaaatcgg
    70081 ttttctttgt ttcaatgctt ccaagatcaa tgcctgttcg aattggtctc gttgaatatt
    70141 tgtttccgtc agttttggat gagggtcttc catgtaaagt tgcggactaa catcctgacc
    70201 gcctgcaaga atgagtttgt cgattttctc aattagttga ggcgctgaat ctggagacat
    70261 gactggcaga ataagaggta atccttgagc atctaaaact gcatccacaa atccctgcgg
    70321 tgtatagctt acttgatttc cttggaaagt atctgtcgct cgaatcagtt gattcccggc
    70381 aatgccgatg attggtttca tttttattcc ccctaaagta gactaattgt aacaaggatt
    70441 taaaaaaatt taaactatgt aagacttgcc cctatactta tctgttcttg ctgtgttact
    70501 atctgtaaag agaattttcg tgtgaaattc atgacgatag ttgaaaatat tgcttaattt
    70561 gttataataa aaagtaagca gaaataaaaa ggttgggcgt aagcttcaag gatctagttc
    70621 ttcaaggggt gagaaggaca ttttattgaa ggggcctgcc tatactaagt tatctttaga
    70681 ggtacatact ttcaatgaaa aaagaaagca tgtacctctt ttttaaatcg aaaggaagtg
    70741 aagcaagtgt tagaagcttt ggaacaaatc cgaaaagcag aagaagaaaa tgagaagcgt
    70801 gctcgaaccc tacggcagca gttgaagacc tatgcagaag aaaaagagca agaattggag
    70861 ataatccaaa cgaacagtcg gcaacagctg aaacagttgg tagaagaaaa agaacaattc
    70921 gaaaagcaag aattagaaaa agaaaaaatg aaattgaaag cagaagcaga caaggtgcaa
    70981 gcaactttga aagaccaata tcaaaagcat cagagtcaag caatcggtgc aatcattgaa
    71041 agggtgaaag aaacttatgg ccgtcactaa gatggaaaaa gtgaccctca tttcagataa
    71101 aagaaatcag gagaggattt tacaagcagt acaaggaatc caaaatgttg aaatccggga
    71161 tctgtatcaa aatagaacaa acaaccagtg ggtagaaaaa tattttccag ataccacgat
    71221 tattgataaa gaagcaaaat taagcgcttt aggcaatcgg ctgaaagaca tccaagaagc
    71281 tatccaattc atacaacacc acggcgatag ccgtcaaaag aaactccatt tgaaacgtca
    71341 agaactttcc ttacaagact tggaagcaaa ttattccgaa gaaaatttca tgaataaatt
    71401 agaagaggtc cttgatttaa aagaaaagtg ggaacagcta actgaaaaac gtgatcgttt
    71461 agaagaagag gaagaatggc ttcttcattg gcaacagctg gatattgctc caagtatgta
    71521 tgcaagtaag acgaccattt ttgagatggg gactgtgagt gcagcaaatt ttgaaagttt
    71581 caaggaagaa ctaagtaagc ttgatgacgt ttatatggaa gaaatagatt atacgccaaa
    71641 acaagtttat ctttcgtatg ttgctttaaa aaaatcagtt gctgctatag aagaaattgc
    71701 tgggaaatac gggttcaata aagaaacgta tccttatgaa caaaatccta aagaaaaatt
    71761 gcaagaaacc aaacagcaat tatccattgt tcacgagcag caaaaaaaga taacgacagc
    71821 gttaggtcag tgcagcggct atatccaaga atttgaatgg gtagaagaag tcacacttgc
    71881 cgttgcagaa cgggaaaaag taaaagaacg gtttatccat gccacttatc tgatcgtttt
    71941 gcaaggttgg gtagatgcag aagaaaaaca gaatttgatg catgtgttaa acgaaactgt
    72001 atcagaagaa gatatatacg ttagtttcga aacaccaaac tcagaagaga ttcagcagga
    72061 agtccctact aaattgaaaa accatccgct tatcgaacct tttgaattgc tgactgaaat
    72121 gtacagtctg ccaaaatatg aagaagtaga tccaacgcct tggatgacac cattttatct
    72181 tgtcttcttc gggatgatgg tcgcagatgt tggttacgga ttgctgatgc tcattgggac
    72241 aatactagct caaaaactat ttgttttacc ccgcgggatg aaacgtttcg taaaattctt
    72301 tgagattctc tcggtaccat cgatcatctg gggattgatc tacagttcat ttttcggaca
    72361 ggcattacca aaagaactat ttggtatccg cttgcctttc ccaatcctat ctacgacgga
    72421 tgacgtcaat acgattttga ttttatccgt gattttcggt ctgatacaga tcttggttgg
    72481 attattcgtg gcagcaaagg aaaatatcag gaggaaagat tacttgagtg ctgtcagtga
    72541 tggttttgcc tggcaaggga tcctgattgg gatcgttatt gcattgattg gtgtcatgtt
    72601 gataaaaaat acagcatttg tttatcttgg cgcggggcta tcgatcattg ctgctttatg
    72661 tatcttaatc gtgccgatta tccaatcgcc gtctaaagtc aagggtgctg ccaaaggagc
    72721 gtataatctt tacggattga ctggttatat cggtgattta gtcagttata cacgtttgat
    72781 ggcactaggt atttcaggcg gaagtattgg cgcggcattc aatatgctag ttgctttcat
    72841 gccgccagcc gctcgattca gtgtagggat ccttttgatc atcgctttac acgcactgaa
    72901 tatgtttttg acactgttaa gtgcctatgt ccatggtgca cgattgcagt atgtcgaatt
    72961 ttttggaaaa ttttatacag gaggcggacg tgcctttgac ccgctgaaaa cggcggaaaa
    73021 atacgtcaac atcaatcata agaaaaaaaa caataaataa ttggaggatt tttatacaat
    73081 gatggattac ttaattagtc aaaatggtgg aatggtattt gcagtattag cgatggcaac
    73141 agcgacgatt ttttcaggga ttggttcagc taaaggtgtt ggaatgacag gtgaggcagc
    73201 agcagcgtta acaacaagtc aacccgaaaa attcggacag gctttgattc tgcaattgct
    73261 tccaggtacg caagggttgt atggattcgt tatcgccttt ttgattttta tcaacttagg
    73321 aaatgatatg tcagttgtac aaggattgaa ctttctaggc gcttctctgc cgattgcttt
    73381 tacaggtttg ttttcaggta tcgcccaagg gaaagttgca gcagcaggta tccaaatttt
    73441 agcgaaaaaa cctgaacatg ctacaaaagg aatcattttt gctgcgatgg ttgaaacata
    73501 tgcgatttta ggtttcgtta tttccttcct attagtattg aatgcctaag cataaaggag
    73561 gaaaagcaga tgaacgccat tgaaaaaatc atctctcaga tgaatgaagc agcagagcaa
    73621 gaaagagcgg cgttagagca agaagagcga atgaagatcg atcaaaactt tgaacaaaaa
    73681 cgtacgcaaa tcgaaacaga acatcaaaaa caaaaagaaa aacaaatcga attacttgaa
    73741 aaaaaatacc gtcagcttag gaatcgccaa caagtagaag tacgacaaga aaatttgaat
    73801 gcgaagcagg aatttttacg acgattgttt gcagatgcaa tagctgaaat ggagaattgg
    73861 gatgaatctg aacaaatcca gtttatcaaa aattcattgt attcattacc tttgacaggc
    73921 aaagtaacat tcattgctgg agaaaaatca gcagcttatc tttctcagac attgctggat
    73981 gaatggaaca atgaacttcc ctttatgatg gttttaagtg atgaaactgt tgctgatcaa
    74041 gcgggttttc tgataaacga tcaaggagtt cagtataatt ttcttttcag cagccttgta
    74101 caagatatcc aaggaacgat gagttttgag attgccaatc aattattcga ataaggaggg
    74161 atcagtgtat ggaataccac gaactaaatc ccttgattcg cggaagagag cttgaacttt
    74221 tgtccaatga gacatttgaa cggatgattc aaacaaattc tgtcgaagca cttggtgaaa
    74281 tattgaaatc cacgatttac agtccatata tttatgacgg atatgaatat gacttcgaac
    74341 agaatctttt aaaggagcag agccgtctat ttcgctggtt aaaggaatca gcaccggagc
    74401 ctgaaatcgt ttggatctat acgatgcgct atactttcca taatctgaag gttttgacaa
    74461 aagccgagat gacaaatcaa aatctggacc atttgtatat cgacgatgga ttttattcat
    74521 tagaaacctt gaaggatgcc attcatacgc aagtttcaaa tgaactccct gaaagcatta
    74581 tggacagtat acgagaagta cgtgattatt ttgaagagtc taccattctt cagggaattg
    74641 acgtgattta tgatcgacag tttttgacag agcagcgacg gcttgccgat aagctaggat
    74701 atcaagaatt gctgacagaa gtcattgctt ttattgactt gaccaatatc acaacgatgg
    74761 ctcgaggaat attgcagaaa agaacatatg ggttcatgac aacggtactt tccagctcgg
    74821 gaagtatcga aaaagaagta tttttgaact ttgtagataa agatatggaa gattacacga
    74881 attttctatt agagacagat tatgctgatt ttctgcgccc tgtcatccgt gagggaaatc
    74941 ttgatctcgt aaagcttgaa cagttgaaag atgattatct aagttcattg tatcaagaag
    75001 cacaaaccca ggctttcgga ccactgccac tactagcctt tttgaacgca aaagaggtag
    75061 aaagcaaaaa ccttcgttta ctggttatcg gcaaaagaag ccatttcgaa ccagaaacaa
    75121 tcagaaagcg ggtgagacaa gtctatgacg cataagatcg gtgtagttgg cgacaaagat
    75181 tctgttttgc cattcaaatt gtttggcttt gatgttcgtt atggtacaac caagcaaacc
    75241 gttcgtcagg caattgaaga aatggcaaag aatgagtatg gcgtgattta tgtcacagag
    75301 caatgtgcag cattgagccc agaaacgatc gaacgttaca aggaacaaat gatacctgct
    75361 atcgtattga ttcccaatca tcaaggatca ttagggatag ggctggaaga aattcaaaaa
    75421 aacgtagaaa aagcagtagg tcaaaatatc ttatagtatg aaaaggagat agaaattttg
    75481 caaattggaa aaatcataaa agtctccgga cctcttgtaa tggctgagaa catgtctgat
    75541 gccagtatcc aagacatgtg tctagtggga gatctaggag ttatcggaga aattatcgag
    75601 atgcgtggcg atgtggcgtc tattcaagta tatgaagaga cttctggaat tggtccaggc
    75661 gaaccggttc gctctactgg tgaagcttta tctgttgaat taggaccagg gatcatttca
    75721 caaatgtttg acggaatcca acggccatta gataccttta tggaaatcac acaaagtaat
    75781 ttcttagggc gcggagttca attgcccgca ttggaccatg agaaaaaatg gtggttcgaa
    75841 ccaacagtag aagccggaga aacggtgagt gctggagatg ttatcgggat cgtagaagaa
    75901 acaaaagtta taaaacataa aatcatggtg ccaaatggga taaaaggtac gatcaaaaca
    75961 atcgaaaaag gttcattcac tattgatgaa acagtatgtg tcattgaaac cgaaaatggt
    76021 gacaaaaatt tgacgatgct tcaaaaatgg ccagtaagac gtagtcggcc aatcaaagaa
    76081 aaattaaacc cggatgcacc catgatcact ggacagcgag tgattgatac attcttccca
    76141 gtgacaaaag gaggagcagc agctgtacct ggtccttttg gtgcagggaa aacagtcgtt
    76201 cagcatcaaa ttgcaaaatg ggccgatgtg gacatggttg tctatgtggg atgtggcgag
    76261 cgtggaaatg agatgacgga tgttttaaat gaattccctg aattgattga ccctaataca
    76321 ggagaatcgt tgatggaacg tacggtattg attgctaata catcaaacat gccagtagca
    76381 gctcgagaag cttctatcta tacgggaatc acaattgcgg aatatttccg tgacatgggt
    76441 tatgacgttg ctatcatggc agactccact tcacgatggg cagaagcact tcgtgagatg
    76501 agcggacgtt tggaagaaat gcctggtgat gaaggttatc cagcttatct tggttcacgg
    76561 cttgcggaat actatgaacg atctggaaga gtcattgcat taggatcaga aggtcgcgaa
    76621 ggaagtataa ccgcaatcag tgctgtatcg ccgtctggag gggatatttc ggaaccagtc
    76681 acacaaaata cattgcgggt cgtaaaagta ttctggggtc ttgattccag tttagcccaa
    76741 aaaagacatt ttccttcgat cgattggata caaagctatt ctctttattc aacagaagta
    76801 gggaagtata tggatcatat ccttcaagct gactgggcat ccatggtcac cgagggcatg
    76861 cgtattttgc aggaagaaca gcagctgaat gaaatcgtgc gtttggtagg gattgattcc
    76921 ctttcagata atgaccgtct gacattagaa gtggcaaaat ccattcgtga agattatttg
    76981 cagcaaaatg cttttgatga tgtcgataca ttcacttcaa gagagaaaca attcaaaatg
    77041 ttgaagatga tcttgacctt tggtgaagaa ggacgccgtg cgttgtcgtt aggtgcttat
    77101 ttaagtgaga tcatggacgg taccgtatcg attcgtgaaa ggatcggacg aagcaaatat
    77161 atcccggaaa cagaattaga aaaactagat caaattattg gtgaaatcaa gcaaacgatg
    77221 caaacgatcg tttcagaagg aggcatgagc aatgattaaa gaatatcgta cgatcggtga
    77281 agtcgtcggt ccattgatgg cggttgaaaa agttgctggt gtcaaatatg aagaattaat
    77341 cgaagtccgt atgcaaaatg gcgagattcg tcgtggacaa gtattggaag tccaagaaga
    77401 taaagcaatg gtccaaatat tcgaaggaac aagtggtatc aatttacgtg actcttctgt
    77461 acgattttta ggccatcctt tagaactagg tgtatcggaa gacatgatcg gtcgagtatt
    77521 cgatggtttg ggacgaccga aagataacgg accagagatc ctgcctgaaa agcatttgga
    77581 tattaacgga gaagtaatca atccagtagc tcgggattat ccagatgagt ttatccaaac
    77641 aggtatctct gcaatcgatc atttgaatac attagttcgt gggcaaaaat taccagtatt
    77701 ttctggctct ggtcttcctc ataaagaatt agctgctcag atcgcgcgac aagcaacggt
    77761 actcgattca tcagatgatt tcgccgtagt ctttgctgct attggaatca cttttgaaga
    77821 agcagaattt ttcatggaag attttcgtca aacgggcgca atcgaccgtt ctgtcatgtt
    77881 tatgaattta gcaaacgacc ctgcaatcga gcgtatcgct actcctcgta tggctttgac
    77941 tgctgcagaa tatcttgctt atgaaaaggg aatgcatgtt ttggttatca tgacagacat
    78001 gaccaactat gcagaggcat tgcgagagat ttctgcagca cggcgagaag ttccaggaag
    78061 aagaggatat cctgggtatc tttacacgaa cttagctact ttattcgaac gagcaggaag
    78121 aatccgcgga ctaaaaggat cggttactca aattccgatt ctaacaatgc cagaagacga
    78181 taaaactcat ccaatccctg acttgactgg ttatattaca gaaggacaga tcatcttgac
    78241 tagagagctt tacaagagtg ggattcagcc accaattgat gtactcccgt ctctttcgcg
    78301 gttaaaagat aagggaactg gacccggaaa gacaagagaa gaccatgcag ctacgatgaa
    78361 tcagcttttt gcagcctatg cacaaggaaa acaggcaaaa gaattggccg tagttttagg
    78421 tgaatctgct ttatctgatg tagacaagat ctatgcgaag tttgctgagc ggtttgaaaa
    78481 agaatatgtc aatcaaggat tctacacgaa ccgttcgatt actgaaacac ttgatctagg
    78541 gtgggaactg ctatcgatgt tgccaagaac cgaattaaaa cgaatcaaag acgacatgct
    78601 ggacaaatat ctgccagaag ggaagtgagt tctgatggca cgattgaatg tgaatccgac
    78661 ccgcatggaa ttgactcgat tgaaaaaaca gttgacaact gccacaagag ggcataaatt
    78721 attaaaagat aagcaagatg aactgatgcg tcaattcatc ctgttgattc gaaagaacaa
    78781 ccagctgcgt caagaaatgg aagagtctat gacagaagca atgtctgatt ttgtattggc
    78841 aaatgcttcg atcacggagc ctttcatcga agaattattt gttttgccgg cggaaaacgt
    78901 tgatttgtct atcgtagaca aaaatatcat gagtgtaaaa gtacctgtga tgaattttga
    78961 atatgatgaa cagctgacag acacaccttt ggaatacggg tatttgaatt ccagtgccga
    79021 actggatcgg tcaatcgatc ggtttactac cctgcttcca aaacttttgg aactgacaga
    79081 aatcgaaaaa acttgtcaac tgatggcgag tgaaatcgaa aagacacgtc ggcgagtcaa
    79141 tgcattagaa tatatgacga tccctcaatt agaagaaacg atctattata ttcgtatgaa
    79201 gctggaagaa aacgagcgcg cagaagtaac aaggttgatc aaagtaaaaa atatgggtac
    79261 cactgactaa gtggtatcct tttttaaaag aggaaaacga tgattaaaca aagcaaacaa
    79321 ataaagaaac gcttgccggc tgttcagctt ctcgcattag gattttttct cctgatttta
    79381 gttggcggcg gcctacttac cctaccattt tttagtaata gtgggcatgg gacaaatttt
    79441 atcgatgcgc ttttcactgc aacttctgct gtctgtgtga cgggattgac aacattgaat
    79501 acagcagagc attggaacag tgctggtcaa tttttgatca tgcttttgat tgagatcggc
    79561 ggtcttggtt ttatgatggt tccgattcta tgctttgcat tgataaagaa gaaagtcagt
    79621 ctcagcacac gtattatatt aaaagaagcg ctgaatctag aagaagtatc aggtgtgatg
    79681 aagctcatgc tttacatcct gaaatttgcc tttgtgatcc aactgattgg tacggttgct
    79741 ttatcttttg tattcgtgcc tgaatttggc tggttgaaag gtatctggta cagtttgttc
    79801 catgcaatct ctagtttttg taatgcaggg tttgatttgt taggagacag tttagccaat
    79861 caccagcaaa atgtttattt gatcatggtg gtatctgctt tgatcatttc tggtgggtta
    79921 ggcttcatcg tatggcgtga tttactggaa tatcatcaga aaaagaagat aacgattcat
    79981 tcaaaaatcg cattaaccgt tacaggtacc cttttattag gcggattcgt tgtgttcttt
    80041 ttcacagagc gcaatgggga aacgctagtg gaagggaata tgtttcaacg attggcaaac
    80101 acctttttta tgagtgtgac acctagaacg gctggatatt attcagttga ttacctccat
    80161 atgagccatg caggtctgat tttaacgatg tttttgatgt acatcggtgg aacatctggg
    80221 tcgacggccg gcggattgaa aacaactacg ttaggtgtgt tgctgatcca gatgcgttcg
    80281 atgcttaaag gacgtacgag agcggaagca tttggccgta ccatccgaca aggcgcagtg
    80341 ttgcgggcac ttactttatt ttttgttacg ttgacgttgt gtgtagtcgc catcatgatt
    80401 ttatcggtga ctgaaacgat acctaaaact tctggcatcg aatatattgc ttttgaggtc
    80461 ttctctgcgt ttggtacagt aggtcttacg atgggattga cgccagactt gactgcaata
    80521 gggaaattga tcattatagc gcttatgtac attggacgag ttggtgtatt gactgtggtc
    80581 ttctctctga tgacaaaagc acaaagaaca caatcaaaat acaaatatcc agaagaaagt
    80641 gtcatgattg gataatttca tcttctgaca gaaacctagt gatttagtaa aataagaaaa
    80701 taaaataatt tttcttgctt cttggatact ttaagtgcaa aatgttcgtt tattttttga
    80761 ggcactatcc gttgttgaac ctcgggtagt gcctctttct tattgaaagg aatcaataag
    80821 atttgattcc tttatttatc aataggttat aattcatatt tttttatttt ttcttttacg
    80881 atacttagtc cagaagctaa aatttcaagg ttattagagg atagggaaat tcgaacgaat
    80941 gcatctggtt gcgcacgtgt agtaaagcgt ctggaatgat aaagtcggat accgttagca
    81001 agaaagtcat tctcaattat cttaggatca atctcaggat caactggaag aattcgatag
    81061 taagggacac gattcgttgg tttttctact ttgaaaagag aatcaaaaag ctgattggct
    81121 cttttcgtaa gacttaattt agtttctaag atcctatttg cttcatttga atggaggatt
    81181 tgagtgatga cttccacatc taatccagaa gttttcacat ttatattaaa aattgcttgt
    81241 tctatcttgt tttggacatg tactggaact acaagataag caactcgcaa tccagaacaa
    81301 ataaattttg tcattccagc taagtagatt gtttggttag gtaataattt ttggaaagga
    81361 ggaatgatcg tatgttgata gtaagttgtt aaaaatgaat ggatatcatc ttcaataacc
    81421 catagacctt ctttttcaat cacttcggct aattgctctc gtcttttgtg agagatttga
    81481 aaccctatag gattattaca agaaggcata agaaagacac catgaatctt cttttttcta
    81541 cattcctgaa tcaatatatc aggtcgcatt ccttgctcgt caaaatcaat tggaacgatc
    81601 tctaaatgat ataactgagc caattcaatg aaattagcgt atgtatatcg gtctgttgct
    81661 attctatcac ctggagagaa aagtgcagaa agtgtgatag ccaatccatt ttgaacaccg
    81721 gaaacaatag atagagattc taaggacgga atgactcctt gagtttttaa ccaatttgct
    81781 gcagtagtca attgaaaatt tgtgcctttg ggatcttggt aattaagcaa accaacaaga
    81841 tttgggttat tactagttga ttgaataaac gggacaacga atttattaca ttcttcaaaa
    81901 gaactaacca gaccaaaatc aatgatatgt tcggttactt cattggtaga gatggtgatg
    81961 gactcaaaga cattgggaga aataaatgtg ccacttccaa tattcgtata cagcaaacct
    82021 ttctcaattc catatttata agccttgcca acggtagtaa aatttaaatc taaataatca
    82081 gctagctctc tttgggaggg taactgagtg tttttctgta atttattctt taaaatatct
    82141 tgttctaatt gttgaatcaa cgatcgataa taaggacgct tcaatttttg tttgtctggt
    82201 cgccaagtta acgggtaatt gtcataagaa ttaataggca ttttctacac tccttaaaat
    82261 tgtataccat acaattttac cattgattgt attgatttta gaagttaatc ttttgtgagg
    82321 agggaattgt ctatgaaaat tattaatttt gaggaagtag tagcttcttt tagttttgaa
    82381 gaagcgattc aagtaatgaa aaaatgtttt tttgattatg aaagtggtaa aatcagccaa
    82441 aatcctcgat tggtggaaat tttacctgac ggaaaagaca aaaatatgtt tgcgatgatg
    82501 cctgcttatt tgggggagaa cagatatttt ggaacaaaag tcattaccgc ttttccggat
    82561 aatcatcagt atcatttacc ttctcattta ggagagattt tcttgtttga tgctcaaaac
    82621 ggactaccca aagcattgat aaacgcaaat gcagtcacct ggattcgaac agctgctgta
    82681 tctgcgctgg caacagatta cttagcaaat ccgcatgcag aaacacttgc tttaattgga
    82741 gctggtcaac aagcattgtc gcatttgact gcgatttcta ccattcgtcc catcactaca
    82801 gtgtttgttt acgatatttt agaagaaaga cgaaatactt ttatcgctaa agctaaaaaa
    82861 cagtatccta aaataacgtt tataaatgca atatcagtag aagatgcagt acgtccagcg
    82921 gaaatcattt gtacgttgac ctctagtaaa gaggcatttc ttcaaaaaga gtgggtaagg
    82981 gaagacgcac atatcaatgc tgtgggcaca tttactcctg atacaagaga gataagtaca
    83041 tcgttgatgg aaacttctca aatctatgta gatgattact cagctacctt aacagaaagc
    83101 ggggacctgc ttatagccat ggcagaagga gatttagagg aatcttgtat tgttggtaca
    83161 ttaggcgaat tagtttctga gaaaaaaaca ttttataaag gagaatcgag gccgacgatt
    83221 ttcgacgcag ttggtctagc tattgaagat ctttgttgtg cagaatatat ttataacaaa
    83281 ttagagaaag gggctttaaa atgaacttag attattacgt agttgatgca tttgcagatg
    83341 aggtgttcaa aggaaatcca gcagcggttt atgtgctaga agaatggctg ccagaaggta
    83401 cgatgcaaaa aattgccatt gaaaacaatt tatctgaaac agcatttaca gtgaagaaaa
    83461 accaagaatt tgagcttaga tggtttacgc cagatcgaga aatcgatctt tgtggtcacg
    83521 cgacattagc aacagcattt gttttattta actattacaa aatacctgat gaaacgatta
    83581 aattttctac tcaaagcggt aatctatttg tgacaagaat taaagattat tattacatgg
    83641 attttcctag tattatgccg aaaaaagtgc cgatattgac tgaatatgaa gaagcaattg
    83701 gggctaagat taaagaagcc tacttagcac gtgatttatt tttcgtatta gaagatgaaa
    83761 aaacggtggc taaattgcag ccagatttta cagctatcaa aaattttgaa ttaggaatag
    83821 agtcatcgtg acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa
    83881 attaacaatc aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg
    83941 ggcagaaaga atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga
    84001 tctagaatgt gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc
    84061 taaaggtacc tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt
    84121 ggcagcctta tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa
    84181 aagtttgcgt ctttttttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc
    84241 cccatactaa ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt
    84301 agtaagaagg cgtagtgcca ggtaatcctt ttaagtcagt aatctcaaga cctgcagctt
    84361 tatgttgctc gtgtaatttt tctaaatcat cagctgcaat agcgatatga ccatagccgt
    84421 ctcctagatc atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatctc
    84481 caggaagtgt caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt
    84541 cttcaaaacc aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcacccgaa
    84601 cacatgtgtg agccattttc ataaattcat ctctcctttt ccttttactc aatcataaca
    84661 aaaagaagta agaaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg
    84721 gatagaaaat aatactgtta aggtggaaac aattcatgga taaaccaatt tttggtgaaa
    84781 aaaagcaatc tgctaattat caaacccgtt atgcagcata tattgtcata gaaagagaca
    84841 agcggattgc ggtgatcgag gctccaaatg gtgctttttt ccttcctggt ggggaaatcg
    84901 aaggagaaga gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg
    84961 tggcagaaat ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg
    85021 caacttatta ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag
    85081 aaccaactga aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat
    85141 tgaaacgtgg tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa
    85201 agaaagcgag tagatcagct ttctctcagt ttttttattt attacagtac atattttttg
    85261 attgcttcag ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg
    85321 acaagagaaa cggcatttcc cattgctact cctagaccag catattcaat catggataag
    85381 tcgttctcgt tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg
    85441 agattcgcaa ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc
    85501 gcacttttga ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca
    85561 tctaaaattt ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt
    85621 tcttcaggtg ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa
    85681 gcgctgatat ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg
    85741 ccgacacggc gtgccatcac ttcgatctct aggaaatctt catgagtcag tccgtgacgg
    85801 gcgatgattt tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa
    85861 tcattatctt gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg
    85921 ccagtgcata aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact
    85981 tcttttgtta cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt
    86041 ttgatagaca taatttcctc caatatattt taatttattt caatcaatgc gccattacgg
    86101 atatggctgg caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggag
    86161 ggatcaacca tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat
    86221 gcagcaacaa gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc
    86281 tcgatttgtg tgcgatgtct gccttgttct gggcgataaa aatcataagg cagatcgtag
    86341 ctagaattca cagcagtgta ataaacaggg ttatagccaa ccttttctac taacaaagtg
    86401 agttcttgga ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta
    86461 cgattcaaaa aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga
    86521 gtaaagtaag tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt
    86581 ccgtcaagaa atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga
    86641 tacaactcgt gtgcgcgatg aagcagatgc tccaaaatca cttccatacc acgggaaaca
    86701 ggatggaagt acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca
    86761 tgcatgccac tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt
    86821 cgggtaagat caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag
    86881 tccattcgat ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa
    86941 gttttttgga tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc
    87001 tgatacactt ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta
    87061 tggaagatat gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc
    87121 gcacataaag tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt
    87181 gaaaaatttc gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa
    87241 tgggtaaaac ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta
    87301 atgcgtcgta aacgttggac ttctttcgaa ttgatcaaat ctaagattac tttatgctgg
    87361 acatggatat agttatggac tggatcacga aaaacttttt ccataggcag catttgatat
    87421 ttataagggg ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat
    87481 ttggttgttc cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa
    87541 atcacttgca gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac
    87601 aaaaaggggt tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg
    87661 atagccattt gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg
    87721 cccgcgtttt tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt
    87781 gatccgacgc tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc
    87841 aggacaataa gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt
    87901 agtcaatagg agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg
    87961 agggaaaatc aaagaaatat ttaaaattcc ttcatctgat acgatcccta atccacctga
    88021 atttctgatc actggagcgt aacctgcatc tttcagtgtt tggatcccgt cacttagaaa
    88081 aggagttcga acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa
    88141 aaagatttgc tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga
    88201 aaagtcgttt ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc
    88261 tcctttgtat aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg
    88321 gaaaaaaggt tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac
    88381 aatgtagcta tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt
    88441 tcaatcaaat tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat
    88501 ttgaaagggc aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag
    88561 gaggagacgg gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag
    88621 ctgatccgtg caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa
    88681 acatcctatc gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat
    88741 gttagtttga aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg
    88801 ggaccggaaa aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag
    88861 aaaagtttga ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg
    88921 tcctgattgg aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa
    88981 gtagcacacg cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac
    89041 cagatccaaa actatcttga gaaatcagac agtgaaattc gtgattcact cgcacaattt
    89101 tatactgact tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg
    89161 cgttcatggt atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag
    89221 gatgaagata ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat
    89281 gaagacgcga tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat
    89341 gacgatgatc tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct
    89401 gacttgcaag aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat
    89461 atcgaagaag atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa
    89521 gaattttctg actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga
    89581 cgatcagcct atcagaataa ggaggtgtga cacgatttt
//
LOCUS       DARPZJ010000006        80737 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.006, whole genome shotgun sequence.
ACCESSION   DARPZJ010000006 DARPZJ010000000
VERSION     DARPZJ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.006"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            9..329
                     /locus_tag="SLE23_000520"
     CDS             9..329
                     /locus_tag="SLE23_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HEI8467449.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(441..1310)
                     /locus_tag="SLE23_000521"
     CDS             complement(441..1310)
                     /locus_tag="SLE23_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8467450.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(1406..2710)
                     /locus_tag="SLE23_000522"
     CDS             complement(1406..2710)
                     /locus_tag="SLE23_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8467451.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(2707..3216)
                     /locus_tag="SLE23_000523"
     CDS             complement(2707..3216)
                     /locus_tag="SLE23_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467452.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(3391..5526)
                     /locus_tag="SLE23_000524"
     CDS             complement(3391..5526)
                     /locus_tag="SLE23_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8467453.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(5609..7264)
                     /locus_tag="SLE23_000525"
     CDS             complement(5609..7264)
                     /locus_tag="SLE23_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8467454.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(7266..7580)
                     /locus_tag="SLE23_000526"
     CDS             complement(7266..7580)
                     /locus_tag="SLE23_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEI8467455.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            7750..8010
                     /locus_tag="SLE23_000527"
     CDS             7750..8010
                     /locus_tag="SLE23_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEI8467456.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            8024..8338
                     /locus_tag="SLE23_000528"
     CDS             8024..8338
                     /locus_tag="SLE23_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HEI8467457.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(9068..9622)
                     /locus_tag="SLE23_000529"
     CDS             complement(9068..9622)
                     /locus_tag="SLE23_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEI8467458.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(9748..11677)
                     /locus_tag="SLE23_000530"
                     /pseudo
     CDS             complement(9748..11677)
                     /locus_tag="SLE23_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(11983..12699)
                     /locus_tag="SLE23_000531"
     CDS             complement(11983..12699)
                     /locus_tag="SLE23_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEI8467459.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(12700..14523)
                     /gene="glpO"
                     /locus_tag="SLE23_000532"
     CDS             complement(12700..14523)
                     /gene="glpO"
                     /locus_tag="SLE23_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEI8467460.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(14537..16033)
                     /gene="glpK"
                     /locus_tag="SLE23_000533"
     CDS             complement(14537..16033)
                     /gene="glpK"
                     /locus_tag="SLE23_000533"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEI8467461.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(16169..17629)
                     /locus_tag="SLE23_000534"
     CDS             complement(16169..17629)
                     /locus_tag="SLE23_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467462.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(17619..18914)
                     /locus_tag="SLE23_000535"
     CDS             complement(17619..18914)
                     /locus_tag="SLE23_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8467463.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(19246..19923)
                     /locus_tag="SLE23_000536"
     CDS             complement(19246..19923)
                     /locus_tag="SLE23_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HEI8467464.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(19953..21044)
                     /locus_tag="SLE23_000537"
     CDS             complement(19953..21044)
                     /locus_tag="SLE23_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEI8467465.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(21145..21579)
                     /locus_tag="SLE23_000538"
     CDS             complement(21145..21579)
                     /locus_tag="SLE23_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8467466.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(22163..23620)
                     /gene="ascB"
                     /locus_tag="SLE23_000539"
     CDS             complement(22163..23620)
                     /gene="ascB"
                     /locus_tag="SLE23_000539"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEI8467467.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(23617..25512)
                     /locus_tag="SLE23_000540"
     CDS             complement(23617..25512)
                     /locus_tag="SLE23_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8467468.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(25570..27345)
                     /locus_tag="SLE23_000541"
     CDS             complement(25570..27345)
                     /locus_tag="SLE23_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEI8467469.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(27395..28891)
                     /locus_tag="SLE23_000542"
     CDS             complement(27395..28891)
                     /locus_tag="SLE23_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8467470.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(29085..30707)
                     /locus_tag="SLE23_000543"
     CDS             complement(29085..30707)
                     /locus_tag="SLE23_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEI8467471.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(31035..32348)
                     /locus_tag="SLE23_000544"
     CDS             complement(31035..32348)
                     /locus_tag="SLE23_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEI8467472.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(32593..32817)
                     /locus_tag="SLE23_000545"
     CDS             complement(32593..32817)
                     /locus_tag="SLE23_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467473.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(32837..33259)
                     /locus_tag="SLE23_000546"
     CDS             complement(32837..33259)
                     /locus_tag="SLE23_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEI8467474.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(33402..34112)
                     /locus_tag="SLE23_000547"
     CDS             complement(33402..34112)
                     /locus_tag="SLE23_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467475.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(34130..34627)
                     /locus_tag="SLE23_000548"
     CDS             complement(34130..34627)
                     /locus_tag="SLE23_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467476.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(34664..35116)
                     /locus_tag="SLE23_000549"
     CDS             complement(34664..35116)
                     /locus_tag="SLE23_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8467477.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(35251..35856)
                     /locus_tag="SLE23_000550"
     CDS             complement(35251..35856)
                     /locus_tag="SLE23_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEI8467478.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(36306..36926)
                     /locus_tag="SLE23_000551"
     CDS             complement(36306..36926)
                     /locus_tag="SLE23_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEI8467479.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(36928..37797)
                     /locus_tag="SLE23_000552"
     CDS             complement(36928..37797)
                     /locus_tag="SLE23_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HEI8467480.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(37820..38227)
                     /locus_tag="SLE23_000553"
     CDS             complement(37820..38227)
                     /locus_tag="SLE23_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEI8467481.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(38246..39535)
                     /locus_tag="SLE23_000554"
     CDS             complement(38246..39535)
                     /locus_tag="SLE23_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8467482.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(39562..39864)
                     /locus_tag="SLE23_000555"
     CDS             complement(39562..39864)
                     /locus_tag="SLE23_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8467483.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(39889..41982)
                     /locus_tag="SLE23_000556"
     CDS             complement(39889..41982)
                     /locus_tag="SLE23_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8467484.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(42471..43235)
                     /locus_tag="SLE23_000557"
     CDS             complement(42471..43235)
                     /locus_tag="SLE23_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HEI8467485.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(43346..44215)
                     /gene="mdcB"
                     /locus_tag="SLE23_000558"
     CDS             complement(43346..44215)
                     /gene="mdcB"
                     /locus_tag="SLE23_000558"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HEI8467486.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(44240..45316)
                     /locus_tag="SLE23_000559"
     CDS             complement(44240..45316)
                     /locus_tag="SLE23_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEI8467487.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(45340..45933)
                     /locus_tag="SLE23_000560"
     CDS             complement(45340..45933)
                     /locus_tag="SLE23_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HEI8467488.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(45937..47613)
                     /gene="mdcD"
                     /locus_tag="SLE23_000561"
     CDS             complement(45937..47613)
                     /gene="mdcD"
                     /locus_tag="SLE23_000561"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HEI8467489.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(47603..47902)
                     /locus_tag="SLE23_000562"
     CDS             complement(47603..47902)
                     /locus_tag="SLE23_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HEI8467490.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(48004..49650)
                     /gene="mdcA"
                     /locus_tag="SLE23_000563"
     CDS             complement(48004..49650)
                     /gene="mdcA"
                     /locus_tag="SLE23_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HEI8467491.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(49657..50568)
                     /locus_tag="SLE23_000564"
     CDS             complement(49657..50568)
                     /locus_tag="SLE23_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEI8467492.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            50688..51545
                     /locus_tag="SLE23_000565"
     CDS             50688..51545
                     /locus_tag="SLE23_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8467493.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(51732..52094)
                     /locus_tag="SLE23_000566"
     CDS             complement(51732..52094)
                     /locus_tag="SLE23_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEI8467494.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            52440..53879
                     /locus_tag="SLE23_000567"
     CDS             52440..53879
                     /locus_tag="SLE23_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467495.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(53886..56438)
                     /locus_tag="SLE23_000568"
     CDS             complement(53886..56438)
                     /locus_tag="SLE23_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEI8467496.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(56552..57883)
                     /locus_tag="SLE23_000569"
     CDS             complement(56552..57883)
                     /locus_tag="SLE23_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467497.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(57849..59327)
                     /locus_tag="SLE23_000570"
     CDS             complement(57849..59327)
                     /locus_tag="SLE23_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467498.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(59632..61467)
                     /gene="tdc"
                     /locus_tag="SLE23_000571"
     CDS             complement(59632..61467)
                     /gene="tdc"
                     /locus_tag="SLE23_000571"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEI8467499.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            61937..63364
                     /locus_tag="SLE23_000572"
     CDS             61937..63364
                     /locus_tag="SLE23_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467500.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(63456..63821)
                     /locus_tag="SLE23_000573"
     CDS             complement(63456..63821)
                     /locus_tag="SLE23_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEI8467501.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(63818..64183)
                     /locus_tag="SLE23_000574"
     CDS             complement(63818..64183)
                     /locus_tag="SLE23_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEI8467502.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(64375..64623)
                     /locus_tag="SLE23_000575"
     CDS             complement(64375..64623)
                     /locus_tag="SLE23_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467503.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            64622..64750
                     /locus_tag="SLE23_000576"
     CDS             64622..64750
                     /locus_tag="SLE23_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HEI8467504.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            64807..66501
                     /locus_tag="SLE23_000577"
     CDS             64807..66501
                     /locus_tag="SLE23_000577"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEI8467505.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            66505..66624
                     /locus_tag="SLE23_000578"
                     /pseudo
     CDS             66505..66624
                     /locus_tag="SLE23_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            67275..68408
                     /locus_tag="SLE23_000579"
     CDS             67275..68408
                     /locus_tag="SLE23_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEI8467506.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            68439..68759
                     /locus_tag="SLE23_000580"
     CDS             68439..68759
                     /locus_tag="SLE23_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HEI8467507.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(68788..69252)
                     /locus_tag="SLE23_000581"
     CDS             complement(68788..69252)
                     /locus_tag="SLE23_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467508.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(69384..70638)
                     /locus_tag="SLE23_000582"
                     /pseudo
     CDS             complement(69384..70638)
                     /locus_tag="SLE23_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(70667..70984)
                     /locus_tag="SLE23_000583"
     CDS             complement(70667..70984)
                     /locus_tag="SLE23_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEI8467509.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(71010..71330)
                     /locus_tag="SLE23_000584"
     CDS             complement(71010..71330)
                     /locus_tag="SLE23_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8467510.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(71794..73209)
                     /locus_tag="SLE23_000585"
     CDS             complement(71794..73209)
                     /locus_tag="SLE23_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8467511.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(73226..74542)
                     /locus_tag="SLE23_000586"
     CDS             complement(73226..74542)
                     /locus_tag="SLE23_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8467512.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(74692..75390)
                     /locus_tag="SLE23_000587"
     CDS             complement(74692..75390)
                     /locus_tag="SLE23_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEI8467513.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(75679..76635)
                     /locus_tag="SLE23_000588"
     CDS             complement(75679..76635)
                     /locus_tag="SLE23_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8467514.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(76748..77581)
                     /gene="msrA"
                     /locus_tag="SLE23_000589"
     CDS             complement(76748..77581)
                     /gene="msrA"
                     /locus_tag="SLE23_000589"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8467515.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(77756..79384)
                     /locus_tag="SLE23_000590"
     CDS             complement(77756..79384)
                     /locus_tag="SLE23_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467516.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIRLVSKGFKNADFIAI
                     FKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDL
                     TTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLL
                     QFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQK
                     IISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPY
                     KTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVAD
                     IKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(79371..80705)
                     /locus_tag="SLE23_000591"
     CDS             complement(79371..80705)
                     /locus_tag="SLE23_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467517.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT        23716 a        16924 c        13615 g        26482 t
ORIGIN      
        1 gtgatcgaat gattacaaca acaacgaaca gtgtagaggg aaaagccgta gtagcttata
       61 aagggatcgt ttttggtgag gtcattactg ggatccatgc atttaaagac ttggaggcgg
      121 ggttgcgaaa tatctttggc ggccgctcaa aaagctatga aaacgaacta atgggtgcaa
      181 gagaagaagc acttgccgaa atggccgaac gtgcaaaagc attaggagct gatgcgatca
      241 ttggcgtaaa aatggactat gaagtattag gcagcgacaa tggcatgctg atggtcacat
      301 gtagtggaac agctgtctcc acgagataag taggggacat ctgttttaat aactaaagag
      361 agatgggaca tgtagtggca ctcaagaatt agatttttca gtctaacttc gaggtactct
      421 accttcccat cctctctttt ttatttcttt ttgcggatga ttccgtaagc tgctgcgact
      481 aacacacccg cccctgctaa ggaataactg acagaagctg ttttttcatt tgtttttggc
      541 aaagtctgac ttgttgattt ggatggctct gtcgtttgct gaactgtttc tgtcgtgctt
      601 ccagaggtca ctgatttttc tcctgccgaa tgcaaaatat cttttattcg ttggaaacta
      661 gctgctaagt cagctttttt tgcttcaaaa tcattagcaa ctgtttgtgc ttcgctgatc
      721 tttccgtgga ttgcttgact ggccgctgtg atatccgctt gagtttgact tagctttcca
      781 gaagctgttt gagcaacctg atttaattgc tgattgaatt cttttgcttg ttggatcttc
      841 ccgtcaagat ctgtttggac agcttccgct tttgctttcg cttcggcaag ctttttctca
      901 agttgtgcac ggtcatttcc cactttattt ttaagatcag ctaaatcttg atcgattgct
      961 gcttggtctt ctttcaattt gttttttgca gcttctaatg cttcttcgag ttcttttctt
     1021 ttattttcca agtcttgcaa atgatcgatt tggtcagaag aggtagaact atttattgat
     1081 gtatcttctg aagatgaaat cgtttctcct gaattatctg tcggtacatt ggaagtcatt
     1141 tctgtttccg aggcaccgtt ttcagcacca gaagagctta tggttgttga aggttctgtt
     1201 tgagcaggtt cagaagtttc cgcaaaagct gtctgtccca ataagaaaat actggaaaca
     1261 gcaattggcc agattaacgg cttcattctt tttttcatca cttttcccat ccttactact
     1321 ttttaactaa tttcttatta taagcaaaaa tgtttggaag aaccataaac acaacaggct
     1381 gtttgtctaa aaaacggtgc atcttttatt tttttgtacg ttccgggctt ttccatgtcc
     1441 cgcttccata acctaaaatc gttttgactg ctggaatgaa agtcgtcacg atcgttatcg
     1501 cgttcactat ccagaacaaa agcatatata gtggtgcgaa aagaaggtat ttcaattttc
     1561 ttcgtcgatc atctacaatc agcgaagcta gcaactggaa aaatcctgcg accatttcaa
     1621 agcagatgaa cacaaaactg aatgtaaaag taatataaat ctgttcgtag tttccttgat
     1681 atacataatg cccgattaat ccagcaaaaa gaactacgga aatacaaaag aatattgacc
     1741 agacaatact caatgtttga tcaatgaaga tgatcgttct tccaatatgt ttaaaaggat
     1801 ggagcatcac ttttttgaaa ttcgtcagcc agacttctgt tccacctttt gcccaacgtt
     1861 ttctgtgtcg atatagcatc ttcaacgtca caggtacttc catgaaaaag ataatctcag
     1921 gagcaaaaac agataaccag tcatttaact gatgatccca agcaatactg atgtcttctg
     1981 tcgctcgatc ttgtctgaat ccgcccacat cgatcaaggc ttcttttcga tacatcgtat
     2041 ttgctccact gtacgcataa agaccaccga aaacagctga ctgtgttcgt ttaatgatgc
     2101 ccacgatact tgagaattca accgtttgag attttgcaat caatttggta cgattttgga
     2161 catccatatt tgcagtgacc gcagcaatat gtcttgcacc agggcgaatg aaataattca
     2221 catacctaat cagtgcatct ggctccggta ccgtgtctgc atcattgctt aaaatcaatt
     2281 tcccttttgc aaaggcaagt ccgatattaa acgcgtgggc ttttccttta tttttttcga
     2341 tccgaaccac acgaagatta gcgtattttt tcatcagtct agctaatatt tctggtgttt
     2401 ggtccgttga accatcgtct gtcactaata cctcatagtt gtgataattc aatttcgtca
     2461 tcaaatactc gattgtatat tcgatcacaa tttcttcatt atgggctggc accatgatcg
     2521 tgatgaacgg ttcgacactc aagggaacat ctacccattc tttttgctta tgtttgtata
     2581 aaaacacata acaccagaca ccaataaacc atacaaatcc gcctaaaatc ggataagaaa
     2641 cgagaaaaaa atacataata gacaaacaag tatctaagaa taaattacct gtatgggtga
     2701 ttgagatcat ttcagttcca ccccattttc tttatacaaa tctgcaatga atgtcgtatc
     2761 tagatttttc tcttcggaga cagaataaaa acggaccgtt tctctctctt cttttgttcc
     2821 aaaacgttcc gtatacactt cttcaagtaa ttcttgtctt tttttcaatt tttcatcttc
     2881 atattcaaaa gatttattta cttttttgta tagatttcga ttgttccacc tagtcaatac
     2941 aaatgaggta atcaggaaac tgaaaaaaat caatacaaaa aagccgatta agaaatacag
     3001 cattttcttt tctgataaaa aagcgtacaa ggaaaaatcc ttggctcttt ctggtctcgt
     3061 taatgggaaa aagacccata taaaaggaag aacaacgatc atccatccta aaagagccac
     3121 taacgtttgc caaatcttta accagtaatt accttttgaa aaatacttat ctttcaccaa
     3181 aattgatgca acttcttctc ttgttacttt tttcatatcc tcacctcacg tttttttgtt
     3241 acgacgtagg agtttaccat acatttcatt tcttttcaca taaagtgttc ctaaattttt
     3301 cctaagaaaa agaacaaaac atttctcatc agcaaatgaa aaatattttg ttctttttat
     3361 cagttgttct ttttattttt tatctcttaa ttatgttgct ctttccaata cgacaatgct
     3421 tttcattcct ctagatatcg ccgtgtacat ttgtctgcgt cttctttgct catctccatc
     3481 gttttcaaat ggatataaga ttacatgatc aaattccagt ccttttgcta gactcaaagg
     3541 aatgatttgg cagttttcta atccatatga atttttttta atcgattctt gtagcgtttg
     3601 ggtttcctct tctgtttggg tgataactgc cgctttttct ccttttagag aaaccaaaat
     3661 ctcagctagt attttcaaca attcttcaga ggatcgaaaa gagcggtatt cgggttcttt
     3721 tccttgcggt cggatcgata cgatgtcgat cttctcttga tccacagcat aggttttgaa
     3781 aagctctgtg attgctccgc tagaacggta actatttcta agatcatacc gatggatcgg
     3841 cagatggtag tcgtcgaaac aacgcataat atcagcaaaa gtagtggaag aattaaagat
     3901 tgcctgattc tcgtcaccta ctaaagtaaa gtgagttttt ggaaataatt cgatcaatag
     3961 acctaattgt gccagggtat aatcttgtac ttcatcaatc aatagatagc gaaatgctgg
     4021 tacatttacc ttttcaacaa gtaaatgacg aatagctaat ataatgactg cttcatcaac
     4081 agtacgtgtg ggttgccaag cataagctga gccatatcgt ttttcataaa ttctttcaaa
     4141 caactgatgc tcatccaccc atgccatttc ttcgatttgt ctggttattt ttcgatattt
     4201 tttttgtaaa agtttccttg cataagctac aatactttgt tccgaatcat cagaaatcaa
     4261 tttaccgaat aattccaact gcctatcttc tgtcaacgag agtacctgat tctgcacagc
     4321 aggacttttt gcttgtttca aaagatgatt cttccattcg ctcatcagtg cctttttcgt
     4381 tgcttgaagc ctatcgatca atttaggatg agcaggaact ttctcatata ttttttcgat
     4441 cgttttttta gaaaggactg tttttccatt tttagtaagt ccacggataa aattcggatg
     4501 atctaaaaac aaaggatctg attgttttag attatcgata aactttttgc tacgcaaacg
     4561 ttctgtctgc tccgatacat tttctcccgt gatacgtttg aaataagcct cttcaccttc
     4621 tatttcctct gctgaaagct gtgaaaccag ctgtatgatg gttagattca gtggatttct
     4681 ttcacctaat gatggtagga cattcgaaat atagtcgata aaccgatgat taggtgatag
     4741 aatcagcaag tcatcggatg tcatcgtatc tcgatataaa tagagcagat acgcaatacg
     4801 ctgcatgata gcagaggttt taccacttcc tgctacgcca tttaccaaga tattttgact
     4861 tttcacatcc cgaatgattg tgttttgttc cgattggatc gtagcagtga tagccttcat
     4921 ttcattggtc tcatcttggc ctaagacttc taataatacg tcatcttgaa tagctacaga
     4981 cgtatcaaaa aacttgacca aacgatctct ttccaaaaga aattgtcgtc tttctttaat
     5041 aaccgtatcg attttatttt gacgaaccgt ataagaagat ggaccaatca tgttattgta
     5101 aaaaagttcg gcaattggtg aacgccaatc ataaacaaga ttttcatctg catcatctgt
     5161 gaaatttgct gtaccgatat aaaaggattc ttttggctca ttatccagaa agtctacaac
     5221 gacttttcca aagtagggac ttttcaataa acgttcgatc tttgctagct gattttctgc
     5281 gtttttctgt ttgatattca tctgatcgat ttctctattt ttcatttcaa tcatcgaaaa
     5341 agtatccagg ttatctaagt aactgtcaaa attcaatcga agctcgccag ccatttcttt
     5401 caacgactgg tttccttcta tttttgccgt atccatcgat tcccgcagtt cgtttttttt
     5461 atcaattagc ttttgataca cgttcttcag atatgcttct tctaactgtt tttgtgtgtt
     5521 gaccatacac attctcctct ttttttaaag tggtggaacc gattagttta cctcttttaa
     5581 gagtcgaatg caagcttttt aacgagtatc atttgttagg atatatcagt tcttcaggtc
     5641 ggacagtttg atataaagaa aatgcaccat caaggttttt tacgtggtag ccagactgct
     5701 tcaagattct ttccgctaga tagctacgta atccgctatg acagctgacg atatattctt
     5761 gttggctgtc taattcattt aatcggtccc gaagttcatt caaagggata tgtttggctt
     5821 ccttgaattt gcccttttcc aattcttctg ctgttcgcac atctaataaa atttttcctt
     5881 ttgctagttc tgtcggcaat tcatgccatt gtacggtttc actaagccct tctgcaatgt
     5941 tcattgctgc atatcctagc atgtttactg gatctttggc tgagccaaat ggcggtgcat
     6001 acgtcaattc taattccggt aaatcgaaga tcgtcaaatg ccctttgatt gctgttgcta
     6061 aaatatcgat ccgtttatcc acaccttttg ccccaacacc ttgtgcacca taaatctcgc
     6121 cagtctctgg atggaagatc aacttcagta aaatatctgt tgcttctgga taatagcttg
     6181 catgatcttt tcctgataca tgaatgactt caaaagacag ttcgttttct ttggctgttc
     6241 tttcacttaa accggtggat gcggcagtca ttccaaacgt tcgtataatt gctgttccaa
     6301 taccgccttg atttcttcga gaaattccgg aaatcgtgtc cgcaacttgt ctaccttgac
     6361 gattggctgg tgaagcaaga gaaataagtg catcttttcc agtgatttgc tgttttacaa
     6421 cgatagcatc ccccaccgca taaatatcag gaatattcgt ttgataacgt tcgtctacta
     6481 ggataccccc gcgtatgcct aattcgattc cagcggtcac tgctagctgg ttatcaggac
     6541 gaacaccaat ggataaaata actaaatcag cagggatggt acgcccatca tccagtcgca
     6601 atcgtttccc gtggtcttca aatccagcga cagcatgaga agtaatcact tctactcctt
     6661 gatgagacaa ttctttttct ataaaagctg ccatttcttc atccagtgtt ggaagaatat
     6721 gtggtgcttg ttcgatcacc atgacttcta aacctcttct ttttaggttt tctgccattt
     6781 ccaatccgat gaatcctgca ccaacgatca cggcacgctt tggctgtttt tctaatgcat
     6841 gcatcacttt atcgatatct ggtacatttc taatagaaaa aacattgtcg gcttctgtta
     6901 tccctggaat cgatggaaca actggttttg caccaggaga taaaaccaat gcatcgtact
     6961 gttcaatgtg tttttgaccc tcatgtacga cttctaccgt tttgttttcg ggaaagatgg
     7021 ctgtcacttc atgatttgga cgcacatcta aacaaaaacg agcggataat gattctggcg
     7081 tttggacaag aagattttcc cgttcactga tttctcccga aagataataa ggcaagccgc
     7141 aatttgcaaa agaaacatac ggtccttttt caaaaacaac gatttctgca tcttccatta
     7201 atcggcgaag ccgtgtagca gcagacattc cacctgctac acctccgaca ataacgattt
     7261 tcatcttatt tccctcctac tgttcgatca aaccattgat tcatgccacc acgtacattc
     7321 actacatcat aaccagattt ctttaattct ttagctgctt gtttactcct catccctgat
     7381 tgacaaatca catagacggt cttttctttg tctccatcat atctgtttat actttgtaat
     7441 ggaacatttt tagctccttt tatatgcccg ccccggtatt ctgcaggtgt tctaacatca
     7501 agtaacgctg gattttccaa aagcttttcc tttaattctg ggactgttat cgattttatt
     7561 gattgaaata gcaaattcat tttctgcacc tcatttacat ttttataaat acctcatggg
     7621 gtatattaaa caggagcttt attaatatgt caaccagaat gactcttcat ttttttcact
     7681 actttttata tttgcataaa ataccgataa ggggtattat ctaattataa aaatagagga
     7741 gaatgtgtta tggagattga taataaaaat atcctgaacc gtttgaaacg tacagaggga
     7801 caaattcgtg gtatccaaaa aatgatcgaa gacgaaaaag aatgtatgga tgtcatcact
     7861 caattaagcg ctgttcgttc tagtattgat cgcgtaatgg gcatgatcgt tgcagataat
     7921 ctgaaaaatt gctttgagaa acctgatagt aatccagaag aacaagcggc taaactagaa
     7981 caagcgatca agatgattat taaaaagtaa aggaatgatt tcaatgaaag tcgttttcca
     8041 tattgatgaa ttagaaaaat ggtcagaaac agggaaaaac gtaaaaaacc tgataaaagc
     8101 ttctccagaa acgacgattg tcgtatctgt aaatggcatc gcgattaccg gttatctaga
     8161 ctctgccaat gcagaattct tagatttgca aggagtcgtt tttcacgctt gcgccaatgc
     8221 tatgcgtgct aatcatattt cagaaagttc tttacctgaa caagtaatcg ttgtaccagc
     8281 aggtgtcctt gatttagttg aactgcaatc ccaaggttat gcttatatca agccttagtc
     8341 agtagaggtt gcgacagaag tgatcagctt caagaaattt cggcttattt ttcgaagaag
     8401 ctacttctgg aaaaccgtga atcaaaggtt gtgaaaacgc tgtcctgcat caagtaataa
     8461 gaacagccaa acaaaaatag cttctcatat ttttcgtttg gttgggctta ttaccgcaga
     8521 tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa tcagcggttt gacctaagta
     8581 ttagagaaaa aaacgggaaa atagctcctc atattttgcc gttttttgag ctaataccga
     8641 aggtcagctg attgaacacc gtttaaggaa gagattgtga aaaagtcgct tagtttcgag
     8701 tattaagaaa aattttgtaa aaatggattt ctacattttt gcataaattt ggcttaatac
     8761 cgagaaactg gcttttgaat accgtttaag gaagaggttg taaaatcagc ggtttgacct
     8821 gagtattaga gaaacaaacg gaaaaatagc tgctcatatt ttgccgtttt ttgagctaat
     8881 accgaaggtc agctgattga acaccgttta ccaagaggtt gtgagcctac catttaactc
     8941 cgaatcacaa gaaataattt caaaaacaac ttctcctgtt tttggttcgg ttggcttatt
     9001 atcgagaagt agctactggg agtctattta tcaaaaaaag gaatgcgaca taggtcacac
     9061 ccctttttta ttttctttga aacatctttc ggtactcgac agcatacaag acaaaagatt
     9121 gtaaaagacc gtaagtgatg acggcaaaaa tgactctcac ccacagcgtt ggtaattctg
     9181 ggaaaagcag caaaaggatc atgccaacat agatgacagc agtcgctact ttgccatacc
     9241 acttcgctcc acttaatttg atatttttag atagcccgat taatccagct acaaacataa
     9301 agccttcttt tatcaagaat agaccaaaca acagccaaag ccacggtcga taccatgcca
     9361 tagacaaaat cagaaaaagt tgtgtcaatt tatctgcaaa cggatcaagc accttcccta
     9421 agtctgttac ctgattatat ctccgagcaa tgaccccgtc tagataatca gacaaacctg
     9481 agacaacaat gaccgctcct gctatataaa atgactgtct cagcacaaaa taaagataaa
     9541 tcggcagcaa aaaaatacgg aatatcgata aaagattcgg aatcgtttgt atttctttac
     9601 gccagtctgt gcttaatttc attttatcgc cctacctcct cagcactctt ttctttttat
     9661 tttagcttac acggggaata aaaccaatga tttcactgtt tttatttttc tttacagaca
     9721 ctgatattat gagctaattt gagataatca cttgctgttt tcatcgttta ctcttctttc
     9781 ttcctgtcgt ttgcgcattt cttttactag tactttatga gctttttttg atcctcgctc
     9841 taggtcacgc tgccgtttac gtgttttata atcgataaac agactgtcta aatcgtaacc
     9901 tgtcgggtac agatcttctg ctgaacgcac cagacgaaca cgctgacgag gcacgtggat
     9961 tatttttttg tctaaatata catcaatcgt atcttcacct atatcttcat aaactaacgc
    10021 ttctttttgg tattcattga caaatatccg atcacctttt gcaaagagct gacgttcttt
    10081 tttattctcc ttcctatttg taactgctgt cttaggaaga aattcttttt tctgtgtccg
    10141 ataggctttt tccgccaagt aacgctctgc ttgatggatc aatttcatcg acatatccat
    10201 tttatgagca atccacaaag cttggctttc tcctgtttct tccaacccgc aactgatatt
    10261 taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct tcatgatctc
    10321 cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc ccttgctcat
    10381 acatagattc catgattgcg atcgctagtg cagccccttc atttggctct gttccactgc
    10441 caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata gcagcgatgt
    10501 tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg tcaccgacat
    10561 cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga acttgcatac
    10621 cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt ttgcctccgg
    10681 catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca tccaatggta
    10741 ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt tccgatttat
    10801 tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca aagatgatat
    10861 ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct gcgatagcac
    10921 cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt aacaactgat
    10981 agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt cttttatttg
    11041 attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata ggaatcgtat
    11101 agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt ttcggatgac
    11161 gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat tgtttgcgta
    11221 ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt ttctggtcaa
    11281 tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac aacaagggtg
    11341 tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta agaaaatccg
    11401 catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt tctgtcagtg
    11461 catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag atcaagcgtg
    11521 cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag accgtcatat
    11581 cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc tttttgatcc
    11641 gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt cttgaagaga
    11701 tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac acagcttaaa
    11761 aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca ggtaccgttt
    11821 cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt agataccagc
    11881 tacactcaca aaacataccc cattcttcta ggtcttattt attttccact taactatagc
    11941 aagacacatt ttggttgtca aactttagta tgttttatag atttacacca ttaatgaata
    12001 gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc atgaatatgc
    12061 ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc gaggaccaaa
    12121 gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac cgatggctaa
    12181 gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt gtccaaaagc
    12241 tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat ttgctggata
    12301 attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat ctttcgttgc
    12361 attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag ctcctaaaac
    12421 ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca tcgccatagc
    12481 tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat agacagccat
    12541 tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct gtgctttact
    12601 tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga tcagtgtccc
    12661 aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc cctttagttc
    12721 ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg ccttctcctc
    12781 ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga tctcatcaag
    12841 ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc ctggggccaa
    12901 aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac tcaaaccagg
    12961 ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc cgtaaaaatc
    13021 agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt ttgctaattc
    13081 tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct gatatttttt
    13141 agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc gtatcaatcg
    13201 caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata aagtcagcaa
    13261 accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg ctttttcatc
    13321 acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa ctttgttttc
    13381 cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa tcgatccatt
    13441 atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa gtcctgccca
    13501 gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat tgatcacatc
    13561 caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc cttggtaatc
    13621 cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa ccatccgccc
    13681 atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt tcgcatctac
    13741 aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg taaaattcaa
    13801 gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg ctttgatttc
    13861 gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat cgccatcata
    13921 taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg cagccttttt
    13981 gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga cacccgcgcc
    14041 ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg gtgtcagcgt
    14101 ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt ccattgctac
    14161 tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg gcaaaagcat
    14221 tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt caccaactgt
    14281 gtcagctact acttccacat caaatgtctt cagataacga ataccgccat gaacaagttt
    14341 ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc ctgttttgat
    14401 tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac cgatgatcaa
    14461 cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct tgtttgaaaa
    14521 catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt ttccaaccgt
    14581 tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg ccagcttcat
    14641 aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct gctaaaaatg
    14701 ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca ttcaagatat
    14761 ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact ttcaatacag
    14821 gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact tgataagcaa
    14881 tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc aagccaaaca
    14941 tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat gcaggaacaa
    15001 cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg ctagcttttt
    15061 gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca aaaatacttc
    15121 cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc aataaattat
    15181 ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct gtaccataag
    15241 tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct tgctggtctc
    15301 ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc gtataaccat
    15361 aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt agtaaatcta
    15421 aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga ctggcattcg
    15481 agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa gaatcgatcg
    15541 ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca tgatcaagaa
    15601 tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt ttttcgtgga
    15661 aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac tgtctggatt
    15721 gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt actgttgttt
    15781 cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct gattcgatga
    15841 acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca tgttccaccc
    15901 aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg tgtcttcctt
    15961 tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc atgatatacg
    16021 ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa ctactcttat
    16081 catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc tttttttgac
    16141 agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc gtctctattc
    16201 ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa tattcacact
    16261 gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct tcttcataac
    16321 ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt tgaaaagcaa
    16381 tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt gcaatataaa
    16441 aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc tcactatctt
    16501 cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc agtaactgtg
    16561 ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc tcatagactt
    16621 cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg tagcctactg
    16681 ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc gtttcccgaa
    16741 tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca tactgataaa
    16801 atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc attgtttcgt
    16861 atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga tcgattgctt
    16921 gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg tacgtacttt
    16981 tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt gcttctgctg
    17041 atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt cttttttctg
    17101 gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat agttcataat
    17161 aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt tgtaatccaa
    17221 attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac tcactgatat
    17281 taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa tagacgagca
    17341 tcttaaactt caagctttcc tgcaataaaa acaatagaat tttttccaaa cttacatctt
    17401 cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt ttttccatca
    17461 ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt gacagttgga
    17521 catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg tttcgcaaaa
    17581 tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata ggcagtattc
    17641 gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa tagctcatgt
    17701 tcttctaact gttcaaacgt ccatccttct tctactgcaa ttgtcagttg gtcaagaagg
    17761 tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc agaatcaaat
    17821 agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc tacgtatcct
    17881 gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac gcttcctaag
    17941 aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt tgtctgtgag
    18001 ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac tagagaaaca
    18061 tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat cgcataaacg
    18121 tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc attcaatgtt
    18181 aattgttctt cccacatctg attgtcggga cgagaatgat tagccagcaa aacaagatca
    18241 tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt caaagacaca
    18301 acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac taacggttct
    18361 gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta aagatggatt
    18421 tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc tgcaccaata
    18481 attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt ttgtatcttt
    18541 ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg atttgaacca
    18601 gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac gacttttttt
    18661 tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg gtcagtcagt
    18721 tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt taatatcaaa
    18781 ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata tatttcactt
    18841 gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga cccgccgaca
    18901 attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta acttctcaat
    18961 cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga tgcagcagaa
    19021 tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac tagtggacct
    19081 aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat aaaagaaaaa
    19141 aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa aagacgagtt
    19201 ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat tctttaatgc
    19261 ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg taagaagccg
    19321 cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg ctcctttttc
    19381 tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg cttcctcttc
    19441 ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag actcatctgt
    19501 aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt catttcgata
    19561 gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca ttgttccgtg
    19621 gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag gacgtaaggt
    19681 atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat cgatttcatc
    19741 catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac tgacaaaatc
    19801 tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac ttaaccacaa
    19861 acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga tcaatacttt
    19921 cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt caagaaatta
    19981 tataatgggc ttggcaaata aagctcttta tatgcttctt caaaaggttt cgttacaaat
    20041 tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat catttgctgt
    20101 ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg attgcggatc
    20161 ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac ttcaagaatc
    20221 gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa tgaaacatgc
    20281 agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc ttcaaaacgg
    20341 atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa tggtttttta
    20401 gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa acgataacga
    20461 ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga gaaaaattgt
    20521 tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga ttcaatcgct
    20581 ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc actcattgct
    20641 cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac aggctgttct
    20701 ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat aatcgctttt
    20761 gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat ttcatcatga
    20821 gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc agcaccagta
    20881 ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc ttcggtgatc
    20941 actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg gttcttcaat
    21001 tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat tcctcccata
    21061 attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat tagttgtaca
    21121 tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg catcattcat
    21181 tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg actgatgaag
    21241 ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg taagataaac
    21301 taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta atttttcaac
    21361 aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt tttgtggtat
    21421 tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca gacctgtcct
    21481 tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca cgctaaagaa
    21541 aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc cattggcgta
    21601 catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc cgcctcctct
    21661 gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt tttcgacaaa
    21721 actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt ttgagtatga
    21781 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaaa
    21841 aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct gcatcaagta
    21901 ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag ctaatgccga
    21961 tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg aactccgagt
    22021 cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg acttgtgatc
    22081 gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca agacttttgt
    22141 cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg acttgtctgt
    22201 accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg tcatcttgat
    22261 caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg acgatatcaa
    22321 tgcagcccca cgacgtataa ccaaataaat ctactccatc tttgatagct tccttcatct
    22381 gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt ccatcttctt
    22441 ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt tgatacctat
    22501 catataattg attcaaagca attctcaaac ccttaggatc aatctgccag ccccattcac
    22561 ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg accccttccc
    22621 aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa acaaaatcaa
    22681 cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg acaccttttt
    22741 cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca tcactaaaga
    22801 acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca caagaatacg
    22861 gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata atttcatgac
    22921 aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg tatttcgctt
    22981 gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg tgatgtttta
    23041 cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag cgtttgaata
    23101 ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat ccaccatatt
    23161 ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc tcaatcccat
    23221 attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca ttgggtgttt
    23281 cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag catttaaaac
    23341 ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca tttccgtgtc
    23401 ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc tgatgcgtca
    23461 tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat gtatacacat
    23521 cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga ttggccgctg
    23581 tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc ctaaacttgc
    23641 tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga atctactact
    23701 atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt cttgcaaatc
    23761 tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg cactttgaaa
    23821 gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct ctgctccttc
    23881 ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt ccccgtttac
    23941 agaactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta aagatccact
    24001 agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg caggagtact
    24061 taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga aaagaaaagt
    24121 tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa caaatccttc
    24181 accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag caccggctcc
    24241 tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt aaaatggtcg
    24301 tttatattta agagtcacac cataaacagc aggttcagtg attccaaata atgctgtgat
    24361 aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa ataccccaag
    24421 tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg tatcacgacc
    24481 gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc caaaaatcac
    24541 taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa agttataaac
    24601 agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac ctacaactaa
    24661 taaaataatt gggaccatca cgatgataca aatgaatggt gtcaataaat ttcgaatact
    24721 ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata cagctaaaat
    24781 tgctggaata accgtacttg tataccttgc tagaatcacg ggcatcccta gaaatcgcaa
    24841 ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg ctgcaataac
    24901 catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca aaaatatagg
    24961 caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc ctgattcagt
    25021 agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac cacttcctgc
    25081 caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag agtttaaaat
    25141 gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt tcatttgttt
    25201 ggataatacg tcatacactt catttactgc atttcctact acgacttgaa acattcctcc
    25261 agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat ctgccttctt
    25321 attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc tgacattttc
    25381 ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca tttttacttc
    25441 ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt tcttagaaaa
    25501 cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac aatagtgtgt
    25561 atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta tatcgtttct
    25621 cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat gtataagtgg
    25681 tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa gacagcacaa
    25741 caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga ttagttgctg
    25801 aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt aatgatcaag
    25861 cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa tctgataaat
    25921 ctcccaagat tcaaactcat ctagaacact aggtagataa atcaaatcat cccactcaaa
    25981 aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt ttgattgatt
    26041 tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca tactttgttg
    26101 aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa tcagtatctc
    26161 cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaacaaaat aagcgctttc
    26221 agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta aataaatttc
    26281 taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat gtccggcatc
    26341 catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat ggaacaataa
    26401 cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta gattcttctc
    26461 tatttctttg tttttttcat cattaatcat caaataattt aactctaata gtcgattttc
    26521 aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata acttttttgt
    26581 gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta aaagttcttc
    26641 tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct ctcctgaaac
    26701 aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg gcatgatatt
    26761 ggaaaaaatt gtactgattt gttgaggcaa ccttgcgtgt tggatcaccg tttctgttcc
    26821 aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta gtccttttgt
    26881 cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa tcgtttttat
    26941 ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt gcatactgac
    27001 ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat ccatgctgga
    27061 atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag attcaattga
    27121 ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct cgtagatagc
    27181 aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag cttcagctaa
    27241 ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt ggagttgtcg
    27301 tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg aaaaacctct
    27361 caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat ctatattcaa
    27421 ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct tttttcaatc
    27481 tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca tatcgcttcc
    27541 tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag taaccaatga
    27601 tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt agatactcac
    27661 aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt ccaatgccat
    27721 tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg acataacgaa
    27781 accctagagg atcaattggc caactccaag gttcgggaga tttttccttc aaaaagggat
    27841 tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt ttatagacag
    27901 cgctacgata ataactaaat gcaatataat ctgccgtgtt agcttgcaag cactgttcgt
    27961 ctccatctaa cattactggt gcacagtctt cttccttcca tgtcctgtaa atataagctg
    28021 gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta aattgcagtg
    28081 aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca gaaaagctac
    28141 acataatacc catcttagca tttggatcga ttttctttaa taattgagta gcacgggcgt
    28201 tcgctagaaa catatgatga caggcttgat aaatcacttt ttttgttagt gtagcaatgg
    28261 gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa ggcatacgaa
    28321 aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg tagcgttcaa
    28381 agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc caccccccat
    28441 actctcctac caatgctaag ggggtttcat aatgactaag agtaattact ggctcgatat
    28501 catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc tcatttggct
    28561 tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga aaagctttta
    28621 aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa tcaatcgctt
    28681 catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt ttttcttcat
    28741 tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc acattaggta
    28801 atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct ccgccccata
    28861 aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat caacaatttc
    28921 ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc ggcagaagag
    28981 aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa atacataaga
    29041 cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt tacttccaac
    29101 acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt cagaggataa
    29161 tttgacacaa taacccttaa agcttcacgt ggaatagtga acgtctgctt ttcactggac
    29221 atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc aaagacatgc
    29281 tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg ttttctacgc
    29341 aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa cgcttcttct
    29401 gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt agtaaaccca
    29461 gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc tttcgccttg
    29521 attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt atacatattg
    29581 attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt catgcctaac
    29641 tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat agcaaacatc
    29701 ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat tcgcggaaga
    29761 tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt ttgccatttg
    29821 gataatactt ttttcagttc agagatactc aagggtttca aatcccattt gtctttgcct
    29881 tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc atttctttta
    29941 ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc aacagtcatc
    30001 agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg cagtttaggt
    30061 ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac gtccatacga
    30121 aagcccccaa tacctttatc gatccagaaa ttcatcattt gataaatctc ttggcgaacc
    30181 tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag aaaatattgc
    30241 cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa tctattaggc
    30301 tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt ttctttattt
    30361 ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac cagatccatg
    30421 atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc ttccatcgta
    30481 ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc atcattcgga
    30541 gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag ataatccaac
    30601 ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg aaaacttctt
    30661 ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat tttcctccta
    30721 taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca ctaaaaattg
    30781 taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac aaaaaaacag
    30841 ctgaggaaat tccctcaact gttttttgaa aggattgatt tatgcaggga agaatgctga
    30901 tttcacaact tctttataaa cggtgttcac tcagctgtcc cttggtatta gctcaaaaaa
    30961 cggcaaaata taagaaacta ttttttcgtt tttttctcta atactcaggc cagaacgctg
    31021 atttcacaac ctctttattt cacattcaat atccacatga atcccacaaa tacaaagaac
    31081 agaccataca tgattggaga tacttctttt cctcttttag ctgctaacat ggtaattgga
    31141 tagaagataa aacctaatgc aatcccatct gaaatactat aagtcaaagg catgccgatc
    31201 aagatcaaga atgaagggat cgcaatctct aagtttcccc attcgatttg tcgcaaagat
    31261 tgtgccatca atactcctac cataatcaat gctggtgcag ttacttgtga agtaacaact
    31321 gatagtaatg gagaaaagaa caagcctaac aagaagaaaa tccctgtagt aatagctgtg
    31381 atacctgaac gtcctccaac ggcgatacca gctgatgatt ctacaaatgc accaacagga
    31441 gaagtaccaa ataaggaacc cgcaagcata gctgttgaat cagaagctaa agctttccct
    31501 acacgaggca tcttgttgtc tttcatgaaa cctgcttggt ttgctaatcc aactaaagtt
    31561 cctgctgtat caaagaaagt cacaagcaag aatgtcagca ctacgaccca catttgaaga
    31621 gaattgatgt cccctacatg ttttaatgca actaaaaatg ttggtttcaa acttggtgct
    31681 gcggcaacaa tttcagaagg cattggaatc aaacctgtga ccagacctaa aatcgttgta
    31741 gctgccatcc cgatgaagat gccacctggt acacgccgaa caagcaagat agcagttacg
    31801 actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga gtgatcctaa tcctactaat
    31861 gtagattcat tcgaaacgat gatcccacct tcgctcagac caaggaaagc gataaataga
    31921 ccgataccgc cagaaatcgc atatttcaaa tctgctggga tcgcatcaat gatcatttcc
    31981 cgcagcttga agattgtgat caaaataaaa atcaaagaag caacgaatac gccggctaat
    32041 gctgtttccc atggaatccc cattcctaaa caaacagaat aagcaaaaaa agcattgatc
    32101 ccaagagcag gtgccgttcc aattggataa cgggctaata cccccattaa aacacagccg
    32161 atcgcactgg ctaatgcagt cgcagtaaac actgctcctt catccattcc agaagcacct
    32221 aatacagttg gatttacaaa taagatataa gccattgaga taaatgttgt aaatcctgcc
    32281 agtacctcac gttttaccgt ggtgttcaat ttttctattt cgaagtagga aagtattttt
    32341 tccttcatct tccatccccc taaatccgaa cattataaat aaagtccgtt aaaatttcga
    32401 tttattaata aaacaacgtg ttttatcata tactaaaaca aaacataagt aaacaaaaaa
    32461 ttcggatttt aagcaaaatc cgaacgttcc atctgattaa atccctttat ctcaaagttc
    32521 atgaacattc actttggatt acaagaattt ctttattgtg ttaataaagt ttcttcattc
    32581 tagtctcaaa aatcaatagt gtgatttgat tttaccattt cgtttctgtt cttctttgat
    32641 gaattctttt gtatcgacag gattcagatt atttagtccg ccaaaacctg tatcgaccat
    32701 ttttccccag ccttttgtct tcttttttcc tgatttgaga ttctttgctc gaagcttctc
    32761 actatgtttt gctcgccgat acttcaaata accttctaat cttcccatta gatccactgt
    32821 ttttcctcct ttttattcaa tcagacgact cagcttttcc tataacaaaa taattgcctt
    32881 cagggtcaga aaaattgaaa gtcaagatgc cattgttatc tgtgatttct cctggttctt
    32941 ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa tactaaagaa ggcggtggtc
    33001 ctaatacctc tggtgaaaac ttctgcacaa atacttttgg gaatacgcct aattctaatt
    33061 cttttgagat gctgagtaca atactcttaa attcttctgg caattcgatt gtttcagaaa
    33121 tttctgcacc aattttttct acaaagaatc ggcaaatcat ctctacgtca ttgacataaa
    33181 gcatcacacg tgttttttgt atcatcattt gacccttctt tctatttgat tttctttcct
    33241 gtctataaac tgattccatt atatcacgaa agcgcaaaca ccttgtgttt gatactattc
    33301 aagaaaaata aagcaatagt ttctaggatt gctttcctcc acaaactttt tttacaaaaa
    33361 aaaaaacggc aatgaatgcc gctcttctta tttcgattct tttataattc tgcttctgat
    33421 tcatctttgg ttagtgtgtg tctaacacta gttacgccaa atgtttgatc gattttttcc
    33481 ttcaacgctt cgattgcctg tgcgccacgt gccgcttgtt cagcattgat ggattcaatg
    33541 accagcaccg ctgcttgtgt ttcttccgtc agcatcgttc tttgggcttc acgccagttg
    33601 agacagcgac agatcgctcc ttgttcatca tagtagatga tttcttccgg aagtgccgga
    33661 gcatcggaat ctgcacctaa aggcaggaat gattcgccac cttgggcttt tcctaaatgc
    33721 agatttcctg cgatcttttc gatatcttct ccgccgcaag gtacgccaaa agacaaggaa
    33781 atactattat agatatctac aagcggattg attgggaaaa attcccgttc ttgatttgca
    33841 cgtttcagta aagcttcaat agaagaacgt gcaccttttt tagtcttgaa tgtggtaaat
    33901 gcctgacgcc actgagcaat gacttcgttt tggctgaatg tttcttctgt aaggtaattt
    33961 cttgcttctt ttgctgcctc attcaataat tgatgatacg tttcttcact ttcttttgtt
    34021 acgtggttat cgataccatt tacggataag atttcgatgg ttgcttcagg aaatacttcc
    34081 cagaaattgg tatccactat tacttttttc atctgttcac acctcttgat tagaataatt
    34141 gcttgatgaa tagatagtct gtttggggat catctcccat ataaaaaaca tgttcgctgt
    34201 atttgataaa tcctttttta cgataaaaag cgagcgcaac atcgttgtgt tcccaaacac
    34261 cgagccaaat ggctgttttt tgcttttctt ttgctttttc aatagctgta tctagtaaaa
    34321 atgtaccgat accttgatgt ttaaattttt ttcgtacata gattcgctcg atttctaaaa
    34381 aatgatcagc catttcctca gattgactcg ttcctgtatt tagtttcagg taacccgcag
    34441 gctcttgatc gatactcact aggaaaaaat cggtttcttt atcttttagc tcttctgtaa
    34501 gtttttctag tgcataagct tgtgtcaagt aatcagctaa atgctccggt gaattatctt
    34561 ttccaaatgt atctgtaaat gtttcgatac taatttgttg tagtaagtct acatctgaag
    34621 gcgtcatttt tcgaatttcg tatttattca cggcttcttc ctttcaatag atccttttat
    34681 tgcctttttt gacaaaattc caatcttcgc taacattctt gcatacttta tttaaaagat
    34741 attccaattg ttttgcttct tcgtcagaaa gaccatttaa tgcgactgca ttggagtagt
    34801 tgttttctcg aatgatgaaa ggatagattt ctgctccttt tttagtcgga tagagtttct
    34861 tgattttttt attttcttta tcttccaaac gttcgatcat cccattggat tctaatttct
    34921 tgattgctcg ggcagtcgtt gtacgatcta ctttgatcat ttctgctagt ttttcttgga
    34981 tgattccagg attttcgcaa atacgtacta aataaagata ctgtcctctt gttaaatcga
    35041 cttctttgaa ttcgatattg ctaatagaat ctagcgctcg ggcaatcatt ccgatgtctc
    35101 gaaggatttc agccatttca tcccaccttt attttgtttg taagactagt tcacctcttt
    35161 ttgttgcaaa tgcaactatt ttcaataaaa aaatcaagtt cttttttaat aactagtaaa
    35221 gtatattctt ttcttctttt acgaaaaagc tcaatcacaa tagatctggt ttttgttttc
    35281 taaaataagt aactgtttct tcgttgttcg cttttctgat agctttggca actcttctat
    35341 actaaaaaat cccatgttgg aagtttcatt attctcaata aacttggcct cttcaccgtg
    35401 gatcgcacaa gcaaaaacaa gtttataata ctgaaaaagc tgtggaatat ctttttgttt
    35461 attcgtatca aaaactgctc gcaactgagt agtttctact gttaatcctg tttcttcata
    35521 gacttcttta cgcacatttt cttcaggaga caatcctatt tcagcaaatc caccaggaag
    35581 tgaccattct ttcgtccgtt tatcttcgat tagtaggacc ttgccatctt ttttgatata
    35641 ggcacgaaca tctacttttg gtgttggatg tccttctcca atcgttgtga gcgcttttat
    35701 ttcttcgaaa gtttcttttc ctatttcact gattagttcc aatgaaatcg tccggatctc
    35761 ctcaaaacgc tctttatcaa atacatcttt tccataatat agaccagctt gagaaagtgc
    35821 gagtagtctt ttgtattgag ccaacttctt gttcattctc ttcccttctt ttttagcaaa
    35881 tgtatgacta tgtaatcaag tatagaagac tggtttaatt acggcaaata aatataatga
    35941 aatctgcaat aaataaaaga atgttaaaaa actcgagaac aaaagacatt cgacttctct
    36001 ggggctgtga ataaatggcg ttcaaaagct tgcatctgcg gtaataagcc ccaccaaacg
    36061 aaaaatatga cgagctattc ttgtctggct gttcttatta attgaggcag gacagctttt
    36121 tcacaacctc cccactaaac ggtgttctcc taccaactcc tcggtcacaa gtcacaatat
    36181 tcatcaaaca tgagaagctg tttttttgaa attgctcctt gtgactcgga gctgaacgac
    36241 aggctcacga cctctcggta aacagcgttc aaaagccaat ttttcgatat taagccattt
    36301 ctttgttact tattgtcatt gatttctttt tctaatttat ccaatagtgg agtgtaatcc
    36361 acttgagtat agtctgttac atcaaattca tatagtgttc ctaactggaa tttgtcatat
    36421 tttcggtcgg cgatgatctt tttgaatgct tctttcgtaa tatgattggt ccctttcgtt
    36481 cgatcttcca atacgtcacc atagtgataa tgatccatga tatagctcaa atgacgatct
    36541 gattcacgat cacgtttgta ccgacgttgc cataacactt caaagtctgc tgttaggcga
    36601 atcgtgatca cctgatatcc gtatctatct gctaattctt ggagtcgtgc tttttgctta
    36661 tcactaaaag gatactcgga cacaatcact ttctttcctg cttccatata caaatcaagt
    36721 gctttgtaat agaaaggata aactttcgtc ctttcttgtt ccgcccgttc ttccaaattg
    36781 ttaaacccga tggattctgc atagtattcc ttgatttcat cgagcgtgat ggcatacata
    36841 tctggaaatc gttcccgtag tttattcata agatatgttt ttcctgtacc aggactacca
    36901 gccagaagaa tgaaatactt tttcatctca tttatttcct aagttaattg gactttccaa
    36961 gttcataaac agtccaatct tatgcttgac aatttctttt actgcttcat ttgctggaat
    37021 cacattatgg cgaagagact tgttgatttc tgtttcacta aaggtttctt tagctacttt
    37081 cgtccagttg actaaaagct ccgttccaac attgaatttg cggatcccgt tattgatcaa
    37141 ttcaggataa tcttcttctt tcacacctgt tcctccatgg ataactaggg ggacatcaac
    37201 tactgcatcg atttctttca gcaagggaat gtttacttct gtttttgatt tgaattgtcc
    37261 atgattcgta ccgatagcaa tagctaatgc atccacgcct gtagcttcta caaatttcac
    37321 tgcgtcttcc ggtcttgtat ataccttgtc attttcagcg acatggattc cttcttctgt
    37381 accgccgatt gttccaagtt ctccttctac ggaaacaccg tgcgcatggg catattctac
    37441 tactgctttt gtcttcagga tattttcttt gaaaggcaga tgggacccat catacatgac
    37501 agaagtatat ccgctgtcga ttgcttcttt gatatcatca aagtctcggg cgtggtctaa
    37561 gtgcaagact gcatcaacca tttcttcttc tgcaatagct gtcattacat tgactaacac
    37621 atgcatgccg atatatttag cggtatcgac acttgtttga ataatgatcg gcgaacccat
    37681 ttcttttgct gcgcctagca tagcaggaag catttctagg ttatgcgtat taaaagctcc
    37741 aactgtaaaa ttcaactctt ctgctgtttt tgttacttct ttcaatgttg tatacatctt
    37801 ttattgccac cttatctttt tatttgtttc ctttgatcgt tacttgtttt gcaatttgtc
    37861 gcatctcatc cattttgccc atgtagtaat cgatcccttg atcatcacca gcacgagcag
    37921 catctgcacg cttctggtta tagaggctca tcagtttttt atacccatct ccgatcgtct
    37981 gtttattttc caaactcttt tctaaatatt ggatggcttg atcgttcaca tacaattcag
    38041 aaaatttaag tccaacttgt tcataaagtt tcgctaattt atgcttatct tgggtagtgg
    38101 aaatctcttg tttcaattgt gtaatctctg attgaatctt ttcggtcgct tctggcgata
    38161 gggctttttc ttcttttgcc agaacttttt tcggttcttt ttcttttttc ttaaaaaatc
    38221 caaacatcat tttccctact ttcaattaaa atgctttcaa aactgggctt aagatccagg
    38281 catataagag tgctgcggct actgtatcta catcggttgc tgtagcattg atgaatccca
    38341 tcgaattaaa gatcgttact agcaaagcgg gcaataatgt aataaagaaa ccatgagcaa
    38401 taccgccaat gatcgctcct cggcgtccgc caactgcgtt gccaaatatc cctgctgtcc
    38461 ctccggcaaa gaaattggtt agcataccag gtaaaatcat cgctaagccg aacatgggca
    38521 aagtaaacat ggcaataatc gtaccaatcg ttgtcgtaat gaaacctaaa atgacagcat
    38581 ttgggctata aggaaagaaa actggacaat ctaaggcagg gatcgcatca ggaactaatt
    38641 tcatagctat ccctcgaaat gccggcacga tttcacctaa cagtagacgt acaccagcta
    38701 gcaatacata cacacccact acgaattgga tggcttgtaa aaaggcaaac atgatatagt
    38761 tttgatctcc tgataattca gaagcgaatg gttcgcctgc aaataaaaca gtgatgatat
    38821 atagcgggac catcacgacc atgacagaca aataagtatc ttgcagaaat tcgaaatgtg
    38881 tcggcaactt gatatcttcg atcgactttt tattttcgcc tttctcacca aaaagcttag
    38941 caacaccggc ttcaaataag tacccgatcg tacaaaaatg acctaaagca atatcatttg
    39001 atccagtgat tttacgaatg atcggttgcg ctactgccgg catagcaatg gcgaaacaag
    39061 ctccgataaa atcaccgacc aagatcaata cgatccctcg cagaccggca aaatagccaa
    39121 agactgtcgt catcgttgcc atccataaaa ttgcttgacc agttaaaaaa atgtacttcc
    39181 attttgtgaa acgagccaaa ataatattga atacaaaaat ggctaagaac gtcagtgcaa
    39241 tatctctacc taaacccaaa tcattcattg cttgaccatt gatagattca atagaaggga
    39301 tgatcccttg catatgaaat ccttcagtaa agattttccc gaaataagtt aaacttccaa
    39361 cgatgatgct cgaaccggca ctcaacactt gaaatcctag gagtgtcttt aacgtgccag
    39421 agatgacttg tcctgctgat ttcttctgca gtagtagacc caacatagca atcaatgcaa
    39481 tggtgatcga tgcctgagtc aaaatatttt cgatgataaa attgataacg cccatgtttt
    39541 taccctcttt tctttttgta tttagataac tcccttatct tgcagaactg gggtgatttt
    39601 ttcttcaatt tcattttttg aaacaatatt tttcaaatag atcatcgccg ttttaggatc
    39661 aactgcgaac ttttcgaact gcgaacgaaa attttctgct gtgatgatca catctggttt
    39721 catggaaact gcggaagaaa tatcacaatg gtccagtttg gcttctactc ctaatttgtt
    39781 caaaacatcc tcagcagaca tctgtgctgc aaaactactt cctaaacctg caccgcatac
    39841 gaataaaatg ttcaatttgt tcatctttgt tctcccccgt atcatttatt atttctcaac
    39901 tactgaaaaa agcagttgtt tgaaatcttc gatatttgtg cattcaatca atcgatccaa
    39961 cttctcttcg ttgttgatca attcaattag ttctttcatg atgttcagat gcgagtagga
    40021 gtctactgct gccaaacaaa aaataatctt tactggatcc atttcaggat taccgaaatc
    40081 gattggttgc tcaatcgtag ctacgctgac tcctaattta ttgaccccat cttctggtcg
    40141 ggcatgggct agtgccatgt gtttgccaat cacgatatac ggtccgtaat cattcactgc
    40201 acgaatcatc gcttcgacat agcgctcttc gacaatgttt tctttaacca atggtctagc
    40261 agctagttca atcgattcct cccaagtagt ggctttttct ttgatcatga tattgctgtc
    40321 cgtcaaaata tcttttaaca taggctggat ctcccttttg ttgatttcta aattgtttgt
    40381 ttcgaataat ttttctaact tgccatagat gattcgatct actcggccac cactttcttt
    40441 catgacatct attatttgag tgaataactc cgtcgattca tgactgttag gctctaaccg
    40501 ctgtagttct tcatttcttt tcaaaaagtc ttctataacc aagatattcg tctcagttaa
    40561 aatcggatcg acaactaaaa gcggcttatt tcgataattc aattgaaagg tgctgaaaac
    40621 cagattgaca tccaatttat ctactaattc gatttctttt gaacttaaaa ctgcagtaat
    40681 ctcgatctga ggaaactttt ctttcagatt ctctgctaac agatttccag tagccatccc
    40741 atggttacag acaacgactg atttataaac ataattcaag tctcgcttga ttacactggc
    40801 gatcgtcgaa aagtggatga caagaaaagc tatctcgtcc tccagtatct tgccaccaat
    40861 tacttcttcg atcgtaggaa caaaatgagt gactgcgcgg tagattggga aataatttgt
    40921 tcggatgttt tctttcaatg gattcatgac ttggatatga ttcttgattc ttacaatcag
    40981 tgcagccatg tgcttataga gattttcgaa taaagcttct tcctttagat ggaaaggtac
    41041 gtgtgtctcg ttctctacaa attggatcaa ttggatcgtt agtaattgag cttgtaccca
    41101 ctcgattgaa ttggagatat ctctagcatt gaacgtctca atagtgaaac gaagataatt
    41161 tctttctact tgcgggacat tgtccaattg aaattcctcg atcatgtggt caataaatgc
    41221 agaaaagcta ctgtctttta tttctgtatt tttccaatta atggcagaga taaattcatg
    41281 tttcctgatt cgctggatcc agatcaatgt aaaaagcagg atttgttttt tataaatatc
    41341 atcttcttgt ttcaacaact tattggaata gatctcctgt atttttttga tttccaccaa
    41401 aggaaaataa tggagaaaga ttttttgagc cggtgttaat tgtgcatctt gattcataaa
    41461 gaagtcggtc attcccagat tctgattgat aaaatcatag atcatcgtac ggatagatcg
    41521 ttctgaacct ttataaacca gtccttgctt tccataactg acgatctcta tcccataact
    41581 gaccagtgtt gctcgtaacc gtctcatatc ttcatctaat gtacttttag agatttgaaa
    41641 ttcttcttct tttttgttta gatggatcgg gattcggctg taagcaacgg ctaaaactag
    41701 atcaaaaata cgttcgcgcc gattcaaaaa gccgtctttc acatctttta tttcagtttc
    41761 taatcgagct tgcttttcct tttccagctt caacaaaaaa cctttgttgc gaattgtacg
    41821 gatctccgga agctttttac tgctcaacca gatattcgct tcaagaactt cctgacggat
    41881 cgtccgctga ctgacattga actcacttgc tagatgtttt gcttttactg gatattgggc
    41941 tgtcatgatt ctgtgaagta tttcaattgt tcttgttttc atagaaatga tctccttctg
    42001 atttcaagta tatggttccg cttacataat aaaaagtaga tatttctgcc acttgaagtg
    42061 gaaagaaagt aagcaaagca aacaaaaaat aagccatatg ctttttcatc tcctcaacga
    42121 aaaagacata cgcctattat tacaaaaatt ttgcccatct atacaaaaaa gaggttgtga
    42181 aaaagctgtc ctgcatcaag taataagaac aactaaacta aaatagtgct tcctattttt
    42241 cgtttggttg ttcttattat cgcagatgca agcttttaaa caccatttag tggagaggtt
    42301 gtgacagaga tgttcagcct tgagcgataa gaagcgattt tgaaaaatcg cttcccatat
    42361 tttacaaaat cgtgccttat tgccgatagg ctatctctgg cacaccgttt attcagaaaa
    42421 aggagctgcg acaaggcttt tgtcacaact ccgttcataa atatttcctg tcaatccagc
    42481 ataatcggct gaataaaatc ggcttgccat cttttttctt tctcagaaaa atcaaaatac
    42541 catatctgag aaaaatactg tcgttgtgtc ttacttcctg agatcaatcg cccatctttt
    42601 cgatcgactg aataatcaca gcatctgaaa tcaattcgga tggcaaaact attttcgtgg
    42661 atctgtcgat aatttcctac ttcctgaata gttatttttt tagtatgatt tcttacaccg
    42721 tctgctttgt ttttttgcag aactttctga tgttcggcaa acagcttgtc tgtataacag
    42781 cttctggctt tttcaggagt ttcttcttcc caagcggatt ggatcttcat gaatatcttt
    42841 tggatttcca gaaactgtgc tttcttttct ttagccgttc ctgacatgcg ggacaatatc
    42901 tccgctttca gccttttctt ttgtctttta ttcttgacga tagaaaaagc agaaacccct
    42961 cctactgaca aaacagctaa tgcaagaaat cccgtttgct cataactaga aggacctgta
    43021 cctggaccat aatacccata agaatctctg ccgtaagaac gactgccaaa ataactgccc
    43081 ccatatgaac gaccaccaaa tgaacctctg cccgaacttc gaccgctaga tgtacctcca
    43141 ccatgaccac ccgcgacagc gaatccttgg gtcggcagag caaacaaaca taggcccact
    43201 aacaaaatga ttgctaaata attgattttt ttcattgtct tcctcgttat cttttattac
    43261 aaaaaactat ttttatgata gccttgctaa aaggaagagt caataaccag atgcataaac
    43321 tgttttttta gcaattttgt cttatttagt cattgagtaa catcggacaa atgtatgtgt
    43381 cggcagtcca taattcctct atcttcagca tgaacaagct tgcagacaag agatctgcgc
    43441 ttcctccagg agagatttgg ttttcctgac aaaagtgcaa cagtgctgta aatggacgat
    43501 ttggtaaagc actttgacta gcagcatgag caagtttttg catttccact aacgttttct
    43561 gatcactgcg atgcaatacg catgtgtcat ctagcgaact catcaaaact aacaacatat
    43621 gcatttgttt ctgtacatat gaatcattat ctagctcctt agctgcttga attgcaagcc
    43681 tgatatgcgg ataccctaat atcgcttctt catatgcacc atttacgcca tatttttgct
    43741 tcaccctatg accatgagtg gtttttttat gacgatattt tgtatcagga aaagcagcaa
    43801 gcttgctgac atcatcaagt attttcgata aagaaaaagg ctgttccata ctgatttttt
    43861 gtgcaatgac actgatcaat agccccattg cccaaatcgc tcctttatgg gtattgatgc
    43921 catttgtagc aatcagcatt gccttttccg cttttcgccc aatctcagca attctttctc
    43981 ttaactcctg atcaatagca tgatgccatg ctatttgagc catttcttca aaaaaaggag
    44041 ttagcgtctt agcagactta agaaataaag catagtccat atcggaatgt gcacccgcat
    44101 ccagtgcatc cactaatcca ggttttggac ttaatgttac ttctgcgatc aatgcttcct
    44161 ctaccaacgc agcgagttgc tgagtcactg ctttttttcg ttcgtcattt atcatgacac
    44221 tcactccttc ttcctactat tacttgctga aacctttttt gatagctacc caaatgatat
    44281 gaagtaacca gcttaaagca aatgcacaac ttgccgtcat tagataagct acaagaatca
    44341 tgactcctga aggtaactgc agccaactat ctttaaacaa taataacagt acttggaaaa
    44401 caaatacatt ggctaaatac gtacgataag cataaacaga caaccatttg aacaatggca
    44461 attttggcga atcgtttaca atcattttgg aagcgcctat gaagacagca aagatgatga
    44521 ctaaactgta taaactttgg atcgtattca agtaaggtgc attcgcaaag ctcaagtctc
    44581 ctggatgtgc gagcaatgaa cggacagaaa agaacgcgat aactaaggca acaggtaaga
    44641 aaagataacg tactctgtcc aaatattgat agactttttc gtgataaaca aatgcggcta
    44701 ccccataaat catgaaacta gcaacaaacc gatctaataa gtaccagctg tcatgataag
    44761 gcccagtcaa tacttgtgtt tgatagaaca gataccatgc gacatataaa atcgttgaac
    44821 caatcaatac tggccataca tattttttat tagcaaatac tttgtaaccg agccaaacaa
    44881 aaaacggcat gaacaattgg atctgcagca tcataacggt ataccataaa tgaggcgctc
    44941 catcacctgt gacatatttc agtaaaaagc ttgcagtatc cgtatacgga gtttgttgtt
    45001 ggactgctgg aaatagccaa agataagccg tcgtccatag aagatacgga acgactagtt
    45061 caaaaaactt ttctttcaaa aattcccaat aagacaaatg ctgacttgtt tttaccatat
    45121 tataaacaat tgcaaaaata aacattggtg ctgtgtattt aacgatgacg taaaaggtac
    45181 caagaaaagc tgtatttgtt gcgctgtggc tgtttgccaa agcaaagctc aatatcgttt
    45241 gcatcataac agccgttaca gctgatactt tctggaagtc acttacgttg attttgattt
    45301 ttttgttttc aaacatctct ttctctctct ttttctttat taccaaagtt ctttggttaa
    45361 tttaggtcct tcgactgttt tcaatagaat ttttttctct ggctctctca aatactcttt
    45421 tagtgaaaaa ccgccttgcc gagtcactac ttgggtatcg aattgctcaa aaaaagcagg
    45481 atgcgattga attacctgaa ttggcaattc aatcggtgaa tttgcgtaca gcagcaaatc
    45541 aaaatcactg gtttctttta ctgccggaat cccagtcgat aattcaaatc ctaagctgcc
    45601 gccgattccc catttacatc ctgataatat gtttctagca gcatgaaatt gctgataaac
    45661 aggataatcc atgattttct cttgtctata cgattcttgt tcgatgatgt cccacggatg
    45721 aatgacttgt ttgacggcat gttttgagat ttctgttgac catctctgat tgcgggcagg
    45781 tccacgtaaa ccaatcggta gtatttctgc gtgatccgtc gacgcacgac gaactgttcc
    45841 gaacatcttt tcagttagaa cgacccattc aggcaaggtg aacccttcta tttcatgttt
    45901 atcaaaaagg acaatatcat gtgcttgaat cattttttat gcatcccatt cttcgtccat
    45961 tttggcacgg actttatttg tttcgacacg tccgaatgtt ttggctgttt cgtttgtgta
    46021 tcgatttgtc agcatcgtgt catttgtatt gcggacatct tgaatggctt cattgattgc
    46081 ttcgatgact ttgctgacat tttgttctga agcagcttgg tcggtgatat cttctaggaa
    46141 atgatagatc gctcctagtt ttgtataatt attgatatcg taagcgatag ctggaacttt
    46201 ttcagcagct gcttcgattt cagcaaccga acgttttgtc acacgtgcag cactttcttt
    46261 agacatcgct tggacggtaa tttctttatt gtttaaagca atcaagcggc ttgattgtaa
    46321 tccatgtgct aaaaatgcac ctgaaatagc atttcctgca atcaatccaa taactggatg
    46381 tccagcttga cggagttttg cataagcagc agcactatta gccaaagcca catggatacc
    46441 gatcaattct tcgttatagc cgtatgcttg gcttggtaca tcgatcacaa cgatgattgg
    46501 ccgtttcact tttttgtctt tatcttcttc gtaaacgtga tccaaaattt gtcccatgcg
    46561 gaaaccttca actaaaccaa cttcaccgtt tcgtacacgg tacatcgggt ttttaggatc
    46621 aggtacgatt gatgtcacga tggcttcttc tatgaattta cttgatttac cataatacac
    46681 agtactaata gaagaagttg gatttttcat gccagttagt gccgcaaacc aatcgtaacc
    46741 aacacttgct gcagctggtt catttccttc tgctacttct ggtaagtcaa ttgattttgc
    46801 ttgatggtta gcaattgctt cattgtaatc gtcaatggcc attggttttg aaagatctaa
    46861 agaatcaagt aatgataaat aaaatgctga gctttcactg cgatgcgtgt cttttcgttc
    46921 gtccattgct gcgatgacag cagctttgat tgcttctaca ctatcagtca ctaattcatc
    46981 aatgattttt gattctaccc gttgacgaga tcctaatgta ttccaaatca agtctttgtc
    47041 actagaatca aattctcgaa cgcctgcttc ttgttcaata acttctggtc cattcaaacc
    47101 gactctcgct ttttttgttg cgattaaata actcattaat gctgaagtaa tcgacatacc
    47161 gccaaatgat cctacacgtc ctggaatcaa accgatgact ggtacatatt gttttagagc
    47221 aatgattaca tttccgattt ctgaaataga taacagtccg tagtttgctt cttgcaaacg
    47281 aacaccacct gtatctagta caatgactgg aaagatctca tttccttttt tattttcttc
    47341 taacacatgt tcaagtgcag caacgatttt tgcaccggaa acttcaccga taccgccacc
    47401 ttggaatttt ccttccatag cgattactac tgcttgtttg ccattgatcg tgccacggct
    47461 gacaacgatc ccgtcatcac tttcagggac gattccttgt gctggtaaac ttggcgcgat
    47521 gatttgatcg aatggatcaa tcaattcacg tccattgtca agtagagcgt tcactcgttc
    47581 tctggcgttt aattctacaa aactattttt catctgaaag ttcctccatt gcttgcgtca
    47641 atcgtaggta cacaactcct ggtgtagcac cgaagtcatt gatcacgata tctgctgaaa
    47701 ttggataacg atcaaaaaat ctcgttaata cattgttcca tacttcgccg aagccatcgc
    47761 ttcctgtaca aatttttaca gtagattctg ttttttctgt tggaaacatc aagatttcca
    47821 aatctcctga accgaccact cctacatgga ttttcttatt gatcggctgt ttcgttggat
    47881 atttataagc taattgttcc atggatctct cccctttttg taaaacagag catacacgtt
    47941 ctgcttattc gtctttcttc ttccatctgg gtaaatggcg acaaaaggtt tttctcgcca
    48001 attttatgac caagttctga atttcattgg tggttcatac aggccatctg accattcgat
    48061 caaatcatcg atggtttgtg cagctaataa tgaacgtttc gcttcactac gtttgatgcc
    48121 tagatcttct ggtaatttca cgatgccggc tgcacgcaag ctatctagtg attctttcgt
    48181 gctagtcatt ccaagaggtg taacaccgcc aattgctgca attgctgctt gtcgttcttc
    48241 ttttgttttt gctttgtaca aataagcaat tccttcttct gtcacgatat gtgtagtatc
    48301 ttcgctataa atcatcactg gtgcattggc taagcctgct tgtttttgaa cagctagtgc
    48361 atctaattct tcgacaaaga ctggtttttt atttgaacca tatgtttcaa ccatttgaac
    48421 aactaatttt tggcctttcc ctaatggatc atcattgtcg cgaagtgatt gccatgctgg
    48481 tgtagaatga cgacgaccgc caggattatg tcccatgtta ggcgcaccgc caaaaccaga
    48541 taaacgtcct tttgttacgg tagaagagtt tccttcgtaa tctaattgca aggttgaacc
    48601 gataaacata tcgatggcat attgtcctgc agcttgtgat aatgttcggt tactgcgcat
    48661 cgtgccgtct ttaccgacaa aaaagacatc tgggcgagca gcaatatatt tttccatacc
    48721 aacttcgcca ccaaaactat ggatgctttc aacccaacct gattcgatgg ctggaatcat
    48781 cgttggatgt gggttcaata cccagttctt cgcgattttc ccttttaacc ctagtgattc
    48841 accataagtt ggcagtaaca attcgatagc tgctgtattg aatccaatac cgtgattcaa
    48901 agattgtacg ccgtgttctg cgtagattcc tttgattgcc atcattgcca ttagaatttg
    48961 caattctgtg atgttttgag gatctcgtgt gaataaagct tctaattgat aaggtttatc
    49021 tgctttcacg acaacgtcta cccagtcacc agggatatct acacgtggta aagaatcgac
    49081 aacttcgttg acttgaacga tcacgatacc atctttgaaa gctgcagctt cgatgattgt
    49141 tggtgtttct tccgtattga aacctgtgta caagttgccg tctttatctg ctttatctgc
    49201 agctactaaa acaacatttg gaatcaaatc gatgaataag cgtccataaa gttccaaata
    49261 agtatggata tcacctaatt tcattgtgcc gtcttcaatc atttgggcga cacgcaagct
    49321 ttgtgcacca gcataagaga aatcgatctt gcttgcgatt cctttttcaa aaatattcaa
    49381 atgttctggt cgtgagatac tagacatgat caaatgcaga tcattcactt tttctgcatc
    49441 tactttttca agactttctg aaagaaaact tgcttgtttt tgattgtcgc cttctaatac
    49501 aactttgtcg ccgggagcaa tcagtttttc cattacttct acgatttttt cagtttctac
    49561 atacttgcca ttgagcaagt tgctgatttt ttccaatcgc tgcgcttttt tttcgcgttt
    49621 agaagcccag ttgcggtttg gtttttccat aattagtcat ctccattttt gatatagaaa
    49681 cgtggcgtca tcaataccat gttggtctag attgatcgta cggatccctt tatctacacc
    49741 aaattttgta tgaatcagct ttgtcaaagt attgccgggg ggaaattcaa tcgtcagatc
    49801 cattcctaat tcttttgcca agtccatcat ttggttccac tgcacaggga aagctaggtt
    49861 ttccaacaaa tctttacgaa tctcttctgc gtcctgagtg gctcttccat ccgtattttt
    49921 tatatacaaa catctagcat cagatagatg gacagactgc atatacggct tgaatttctt
    49981 gaccgtatca ttcatcaaga gacagtgaga tggcacaggg actttcagca gcttcgctgt
    50041 ttgcgcttgg tgccgtttgg cttctgccaa cgtaacggat aaaccttcga tactcccaga
    50101 taacgtatgt tgcatcggac aattttcatt tgacagataa actggatggt caggatcaaa
    50161 tgtttttgct acaatttcct cagcttcgct tctcgtcaca cctactacta cgcccattgc
    50221 ataaccgctt ggataagctt ctttcattaa gactgcgcgg tgatagacta gttccgctgc
    50281 attctcaaat ctcaaagatc gacaagcaac agctgcacaa aaagcaccaa tcgaatgtcc
    50341 tgctgcaata tcaggctgaa taccgttttt ttccatttca tctaaataaa atactgcttt
    50401 tgtcagtaat gctagctgga taaaaaccgt atcttgatag ttttcttctt tatcaactaa
    50461 ccgatacccc gtcacatttt ctaaacgttc catgtacatt tcagggatat ccgctaacat
    50521 ccctaacttc tgactgcctt gtccaggaaa taagaaacct gtactcatga gcctcgcctc
    50581 ctcagcactt actttttcca ctgctatctt agtcaatttc tgctataata aaaaatgcca
    50641 aaaaaagaaa aaaccataac aaaaaggtat ggatgggatg gataattatg aaattgcttc
    50701 atctgcagta ttttaaaaaa gtattcgaaa caaaaaatgt tacccaagca gccaaagaat
    50761 tatttatttc tcaacctgcc ttgagccgtg cgatcaaaca tttggaaaac gaattaggtg
    50821 tccctttgtt ttaccatagc ggcagaaaca ttgagacgac cgtttatgca gaagaatttt
    50881 atccatatgc agtcaagaca ttagacacat tagaagaagg aatcaaatta ttgtcttcgg
    50941 tcaatgagaa gatcgttact tccgtcatat tgtatttaga ggtagcctct gtttctattc
    51001 cgaacttggt ccgaattttt atggaaaagc atcctgatat ccaattaacg atcatgcaac
    51061 atcatttacc agatgatatt accgatcctg tactgtacat cacttcggag atgaagcctg
    51121 gcatgaccaa tattcctatc atgaaagaac ctgtttatgt cgccattcct aagaaacatc
    51181 ctcttgctaa aaaagaacat ctgcaattag aagatatcca acgcaccccc atcttgatgc
    51241 tgtcaaagag caacgccttc cgtcatacac tggatgcagc acttgaagcg aaaagtatcg
    51301 aattgacgat cagttcgacg acagatgatc ctgcgacatt acgttctatt gtcaagcaag
    51361 gattagctgt tagctttttc ccaaaagttt cttggtctta cgataaaaat gatcctttcg
    51421 tcttgcggga aatcaaagat ttgcccttga cacgaacaat ttatttatct tctagcttca
    51481 cagaagatca tcctttgatc aaaatgattg caaaaacgat gcgggaattt tatttaggaa
    51541 aataaaaaaa aaagagctgg gacaaaattc ttgtcgcagc tcttttttcg aacaaacggt
    51601 gttccagaag taatttctta gaaaataagc cgaaatttcc caaaaatttg agaagcaatt
    51661 ttcgtaaatt ccttcttatt tcttgaagct aaacatttct gtcacaacct cttctctatt
    51721 gtcctagaca ttcattgcgt tgatttaaaa cttccatcaa tcaaatctgc tagttcatct
    51781 agcttttcta ttttacgtag atcaatagag atccaatgtt ctttattcat gtgataggct
    51841 ggaaaatacc cctcttttcc tcgcaaaatt ccgccaagtt caggatcgac cttcaaatca
    51901 agaatattga tgatcctatg gtcacttgca tcatcataga ttttttcttc tggaacagac
    51961 atcaggaccc caaaccattt tttgcttttt tgatgtctga atacgcaata atcaggaaat
    52021 tttttaaaaa tatattctgg agacaaattg tatgtttcat tgatgtgatc gattagttct
    52081 tttttcgtta gcatctgctt ccatctcttt cttattgatt cgctttattc aaagatacca
    52141 cgtaagaata gaaaaatgaa tacaagtagt tgctaatcaa atacttcgat atttttcttt
    52201 tttatcaact cttaaatgtt caatccgcct gtgttggtct tgctaccatc tactattaaa
    52261 atgtttatta ttgtttgccc acctattttt tgattttagt ggtatcattt ttcaagttca
    52321 tgatgaaatt cttatcatca gtaaatgctc cagaaaaata aacaatgatt gaaaaatcag
    52381 ttgaaacttg accaccgttt attttctccg tattcttaga atagaaggga gtctgattga
    52441 tgtattcact aatgaaaaaa atcattaccg aaaaagatat tcgacgtcat gtttctttag
    52501 tagaacaatt gctgaatcat acaaagataa ccgtaaatga attagctgaa atcataggga
    52561 caaccgaacg aacgattttt tctgaccttc aatctattcg ctctcagctg cccgaaggct
    52621 gggacatcat cagcgatcaa gcaggaatca gtttgcaaaa ccagcaaaat ttattaacaa
    52681 atgacctttg ggagattttt ttcaaacaat cagtcagtgt cgaactgctg aaaaatctgc
    52741 tttttacaaa aaaagttgct gtccctgatt ttctagccga ccatgggctt tcttatggga
    52801 cattgaaaag acatgtgact aaaatcaatc agcgtttagc aagttacgac ttgcagatcg
    52861 atttgacgaa atatacagct tgtattcttg gaaaagagcg tgcgattcgt actttttatc
    52921 atcgattgct gattcctttc actcataaca actatttttt cgaggattat tcgatccatg
    52981 aatcccatta ttttcaattt ttaagaaacc tcagtcaaac tgaactagcg gttgaaacag
    53041 aagagatttt cggaacatgt tggttcttta tcaatacgat ccgtataaaa gcgaattgcc
    53101 gattagattc ttctatccat accaacagca cactctcctc cctgtatgac tctgcattga
    53161 aaaaattgta tttaacggaa ggtatttatc ttaaagacac tgagctttct tttgcttctt
    53221 tctgctttct ggaaagttgg aattacaaca ataactatgg acaagaaacc gctcgctgcc
    53281 tgcatcattc tccattttta gaggtcctcg aaacgtttgt agaggaacta gcttcagagc
    53341 tgtctcttga tcaactaaaa aaaacatctc tgactgataa cttggctctc ctcatattaa
    53401 aatatcatga atcgccgata ttgattgaag cattggaccg tcaataccat cgttttttag
    53461 aaacatatga tcagcaatat gcacacttgt atcaacagaa agagaattta ctgaacgatc
    53521 taaaaaaaga aatagaaatc aatgaaccaa attactttct ccaactcttg tctctactga
    53581 tccaacaaac gattttttct atcaaaccga atttgttcaa tgtctatttt attttccaag
    53641 gagaaccttc atggaaggcg ttcttgcagc aggaattaaa agattactta ggaaaacgtg
    53701 tctgcttctt acctatcgaa ctaaccgatc tttccactat ttcttttgaa aaaacagata
    53761 tcttgatttc caatttccct ctagattctc tagatatccc tattgtatac atttcttcta
    53821 ttccaacgaa aaatgagctc aatcgtttga ctgaactcac tttcaaaact tttttatagt
    53881 aacggctagc gactgtattc tctagctgtt ttttcttttt tgcgaaacag tttgttcatg
    53941 atcccttttt ctatttctac aactaagaat agaagaatca catttgctcc aatcaataac
    54001 tgttgtgtca tcgttaaact tactgtaccg atcagctgct ggccgactgg tagaaaaata
    54061 accatccctt gcaataaagc aaggatacct aatgaaagaa aaagcgcttt gttttgcaaa
    54121 agaccttggt tcaatgacgg cttggacaac tctctgcaat tgatcatgta aacagcttga
    54181 gctaagacga tattttgcag aagaatggtt tgctgtaagc tttgcccttc aaactgcata
    54241 gccaataaat aggcaggaac catgatcagt agggagacat agatgatccg aaacaaatga
    54301 taaccagata ggattccttg ctttggatct cttggtgggc gcttcatgat ttctggatct
    54361 ggcgactcga accctagtgc ataagataaa gtgattgtcg ttaccatatt gacccataaa
    54421 atctgtactg gggacaaagg tagcgggcga ttcagcataa gtgcccaaat caagatcaat
    54481 ccttgagcta atgcagttgg caagaagaaa ttgatggttt tttgcaaatt atccaaaatc
    54541 cgccggccct cttttacggc ttttgcaatc gtatggaaat tatcatctcc taaaaccata
    54601 tcagctgcct gtttgcttac ttcactacct ttgattccca tagcaattcc tacatcggat
    54661 cttttcaaag caggtgcatc atttacgccg tctccggtca ttccgacgat ttctccattt
    54721 ttctgcaaag ctttaacaat tcgcagttta tgttctggtg tcgttcgagc aaagacatcg
    54781 actattggca cttgctgaat caactcttca tcagacataa gatccaaatc gatcccttct
    54841 aaaactttgg cagtatgttt taagccaatt tgttccgcaa tcgcttttgc tgtgtctttg
    54901 tgatcccctg taatcatttt cactgagatc cctgcttgtt ggcattcctt tacagctttg
    54961 actgcacttt cttttggcgg atcgatcaat ccggcgatcc ctgcaaaagt taattgggtt
    55021 aaagtctcat gcgtgagttc ctgtttcgaa tctacttttt tataagcaaa tcctaaaaca
    55081 cgctgacctt ttctcgcaaa ttctgcagct gtctgactcc atgcttcttg ttctgcagaa
    55141 gaaagagttg atttagcaaa taatacttct ggtgcacctt tgacgtaaat caccgctcct
    55201 ttttcctccg catgcatcgt tgccatatat ttgtattcag aactgaacgg aatctttgct
    55261 tctatttttt tcaaaggtag attggctgtt tctgtgtgtc gaatcagcgc aacttctgtc
    55321 ggattgccac ttaaattttc tgttttctgt tcttcttttg tttttaattc ctgacagttt
    55381 ttcataatgg acaacacgca ggcttcttct tttgcagcta catccacaac tgtcatttca
    55441 ttttttgtca atgttcctgt cttatctgaa cagatcactg tcatagaacc taatgtttct
    55501 accgaaggaa gtcctttgat gatcgccttt tcttttgcca tttcatgtac tccaacggat
    55561 agaatcatgg tcaaaacagc tggcaatcct tcgggtacca ttgacaccac caaagcaatc
    55621 gtagccgaaa gaaggatatg ccaatccata ccatatcgaa atgtcgtaaa aataactaag
    55681 aataggctca aacaaagaat gccttgaaaa atttgtttgt ttaatcggtt gattttttta
    55741 atcagaggcg tcgtttgttg ttcgaccgat tgcaatgctt gattgatttt accgatttct
    55801 gtcgtgtttc ctgtttctac aacgacaccg actgcagaac cagattgtac aagcgttcct
    55861 gaaaaaccca tatttttctg gtcgccgatc gattcttctt ctgtcaaaac ggcatgactt
    55921 ttttcagatg cttctgattc tcccgtcaaa atcgattctt ccactaataa atcatgtgct
    55981 tcgattaatc ggatatctgc tggaacgaca tctccggcac gtaagacaat gacatctcct
    56041 tttaccagtt ctttcgcagg gattttttct tgcatcccgt ttgatagtac tatcgcttct
    56101 tgtcccatca gctgcttcaa accattcaat gattcttccg cttttctttc ttgccagtaa
    56161 ctaacgagtc cattgacgat cactacgaat aaaataatac ttccttcaat atattcacta
    56221 gaagcaaatt tcaaaaaaga ggcaatgatc aacacgatca tcagcagatc agtaaaatgc
    56281 tttgctattt ttttccatcg ttttgtctgc tgccttgctt ttatttcatt atatccttga
    56341 tcagtcaggc gtttctgtcg ttcttcttgc gacaagcctt ctgttgatgt ttgatagttt
    56401 ttcaatacat cttctaccgt caatctgtac cagttcatcc tatcccctcc tgtttaattg
    56461 atactgttat tatacgcagg gaagtttttt caggcgtatc gattatttca ggggggtctg
    56521 aaataattcg ttttgcaaaa tgtatctggg cctaactgat atttctattg cttattcttt
    56581 tatatacaaa atttaagaat acaaaccaga taaccaataa aaaaggaata aagcgtgtcg
    56641 tgctttcgaa taacaagctg aaagcaattg aagtaaaaaa caccaacaaa gcaagatctt
    56701 tatatctttg tgtagtgttc cgtttctttt ctttaataaa ttgaacatgt gcacacaaga
    56761 tcgaagacca cacaaataga aaacaactcg ttgtcatgcc tgccaaaagc tgaaaaaaca
    56821 atcgactatc agctacaaaa aaatgtagac aaagaccggc aaaaaataac attcctgtaa
    56881 ttaaaatacc gtgtaaaggt acgcctttct tagaaagcgc acaaaaccaa tggggcaaac
    56941 ttttttcttt tgctgtttga tataaaatcc tgctagtact gtagactgca ctatttgctg
    57001 aggacaaaga agcaaccaaa atcattagat tgacaattgc tgctccgcct tggcaatgga
    57061 tcacttgcag catagtcact aaaggacttt cttttaaatc taaacaatgc catggaacaa
    57121 caaataaaat cgacaaaatc gttcctatat agaaaaagag aatacgccaa ggcagacagt
    57181 tgattgcttt tttcaaattc ttttgcggat cacttgtctc gccaacggtt aagccgatca
    57241 tttcaattcc agcaaaactg aataaaacca taggaaatga gactaccatt ccagcaaagc
    57301 caaacggtag taattcatcg atctgtccaa aattttcttt gattccgata gactgggtat
    57361 gaaaatctga gacactcaat cctataccca ataagataaa aaggaaaatc cccaagatct
    57421 tgatgattga gaaaaaagat tccaattcac caaaccactt gactgcaaca aggttgactg
    57481 ccattaagat cattagtgcg ctacctccgc ttatcaaagc tggtacatgt acaaaccaga
    57541 aatggatata caatcctatt gctgttaatt ccgcaagtcc agctccaagc cagcaaagcc
    57601 aataagtcca attgacaaaa aatgcccact ttttgcctaa ataatagtca acgaaatcac
    57661 tgatagagtt aaatgtacta tttgctaaaa ataaatcacc catggcccgc atcaaaccat
    57721 aaatagccaa accgcatatc aaataaacga gaataacagc tggccctgct gatgcaattg
    57781 cctttgctga acctaaaaat aatcctgttc caattgcgcc acctaatgcg attaactgga
    57841 tatttcgatt agttagagtc cgtttcattg ccggtttttc catcaagttc acctttttct
    57901 ttttcaagca gcatggcgac ttcctgttcc caagaaggtt tctttatttt ttcaatacag
    57961 agtggtacta caaacaaaat gacactgatg gctgtgactg caattagatt gatccatgtt
    58021 ccagctttca tcgtcagtcc gacagaaaat ccgattgccg caaataaaac aataacgaca
    58081 gtccaaactc caagattgct ctttttctct ttttttccaa ttctaaatgg tcgattcaac
    58141 tttgcatgtg tataacgcaa tctcaaaact gcgatcccca tgatgacata gacgatacag
    58201 tagataacag tagttgaatt tacgagcatc aaaaatgctt gattgacgcc aggaatcagc
    58261 aaataaaaaa gtgcaaagat tgagataatg acagactgag tcaaaataac ggatttggat
    58321 acgtcaaatt gattcgtctt ccaaaaattg aattttggtg gatacgcacc ttttctagca
    58381 ctttctgtca ctgtctttgc tggtcctgag gcccaagcag ataattggac tgctacacca
    58441 atgaagacaa gtaaactaaa cagattcaca ataagatgtg gcaaaccaag aatttggcaa
    58501 taaatcgaaa tagattgcgc gatattattc aattccattt gtccttttgg tacgacattt
    58561 gctacaacta aagcattcaa aatattgacg aaaaatataa aaattaacgc ggcaaatact
    58621 ccgcgaatat acgttttaac tggattttcc aatcgagtga tatacacaga ggacatttcg
    58681 ataccagtaa aaataaacat gatcggcgca aaataaacaa atgaggatgc agtcgtagta
    58741 tctggtatta atttgtccca tgaaaaactg cctaatgttc cggttggtac gatcccaact
    58801 ttgatccacg cagcaaaccc taataagagc atcatcgtca aaggcacgta caatcctaac
    58861 caaacaccga cttttccgcc gatttttgcc atatcaaatt tcaaattcaa aaaagtgatg
    58921 atccaataaa cgactaaaat gacaactaat gtaaatttgc tgttcaaacc aagcggcaca
    58981 ttatcgataa tattaccaaa caacggagcg agtgctgaag cgaccatcac catcccagga
    59041 aacatttgga cccataacag ccatgagaca acgaaccccc atttttttcc tagagcattc
    59101 gatacccaaa gttctggacc acctttttgg ggaaacattc cagcaaattc accagagatc
    59161 aatgagattg gaaaagcgta caataatact gcaaccagca tgtaaaaaat catcgtccag
    59221 ctcgttgctg ctacatctgg aatatttcgt acacttgcta caagggcgca ggtcattccg
    59281 ataaaggtca tggtcgtgat ttgctttgat gaaccagtat ctttcatctt tattccttct
    59341 ttcaatagcg acatatgttt ttgttttctt ttatttttgt tcaagaacag aaatgacaag
    59401 gtttcatcga ttcagtacaa aacccagtat caccgaaaca tccattgaac gatcttagtg
    59461 aactgggttt gatacatgaa acgaacgatc caacttatag aacgttttat aaaaaagaat
    59521 atcttggcga ggaatatatg aaaaacaggg ggaaatacaa ttgttttgat gaagcaaata
    59581 attgtctgtt ctccatatgt ctcttgttat tctttcacac aaaaatcagt tctattggat
    59641 gatttcgttt agtttctttt ccattgcttt ggcgattttt tttgtataaa aattgaaaat
    59701 tcgatcatca ttcaaataag gagtcatgat agccgcacgt agcagagtga ttttctgttc
    59761 ttttttccat tcttctttcg ttagacccat tctttcaaca aaacgaatcg gagaatcacc
    59821 gtaatcttct tgtgtaaatg tagtatgaga agtaataaac cgttcaccat aaacatcgcc
    59881 atccatataa gaagaccgat cgaacatttt ttcatttaat tcattgatag cgttcaaatc
    59941 tgtacagcct tgttctttga atacccaatt gaccatatta aaatcaggat gattcaatgg
    60001 atagacttcg attgtttttc ctttaacagt aaaagtcaga tgatcgagaa attctctgaa
    60061 tctttgagct gcctcgattg aagccccaat caattgacca tatccggtca cattcaatgg
    60121 caatacacga tgtgctgtcc agactgcggc ggcggttgct ccagcttttg atccttccaa
    60181 aatataagct cctaacatat ctggagcctt tactgatttt tcaaacacat atggcgcgaa
    60241 ataagaaatg atatttctca tatttttatg tttgattacg attcctccag cagcataagg
    60301 gacatagccc atcttatgag gatctatcgt gacagaatcc gcttctgaaa tagctctgaa
    60361 cccttcatat acctctttgt caatcgttac gcagtggtgg aaaacatgat gttcttcaaa
    60421 gaattcagct aaggaagcat acggcacaaa ttctcctgct tcgtttagaa acagtgaacg
    60481 cgcatagccg ccatatgcgg catcaacatg taaatagaaa tagatccctt catcttttaa
    60541 cctttctctt aattggacga ttttatctac actgtctact tgaccttctt ctgtcgttcc
    60601 tacgacagca accacaccta gaattgggat tttttgtcca gctaattcac gaattgtttt
    60661 ttccaaagca ttaatatcca ttcgataatc ctcttgaact gggatagcaa ccatctgatc
    60721 taagccgact ccgcaaatat ctaacgcctt catccaagaa tagtgttttg tttgagggac
    60781 cagccatttc cctaatcttt ggatattttt tccgctacgg gaagaagctg ctttgacctc
    60841 atccatttct tcgtccgtaa agctttcggt catttccaaa atttcttcaa cagataaatt
    60901 caaaagttcc cactcagaca tttttttcac tttttcaggc agcacttcct tgacagctaa
    60961 aggaatcgat ttgatgcaac gggcgtacca taatccttca agattagcaa tagaaccatc
    61021 tgctgcaatg tgtccccatc cgtctgtcat attgaataat gaagcaaaat cctgtcctac
    61081 ttctgcttcc atttgcgaag ttgccataga agattccaat gcaacattat ttgggttcca
    61141 cagcatcgca tagttgtaag ctaataaagc aggcatcaat gtttcagcat tcatttgtcc
    61201 ccagtaacgg cctgctgaat gccatgggat cgatcctgcg cgtaatcgct gactgacttc
    61261 atccaagacc tctatcatat ggtcgcgggt ggctagataa tctggagtga gcttatctcc
    61321 ttcgctaatt gcaggcatat ctgaaggaat ataattttct ctccatccaa gatgttcatc
    61381 taccatcttg ttcaacaaca ttttataaac tggtccattt tcagctttgt cgcctataaa
    61441 gacggccttg atatccatat ctttcatttt tcttccctcc atattttgtt ggtcaatgtc
    61501 ttgcagatac atgtgtttat ctgtaacacc tcttcactat agcgccaaaa atgagaattt
    61561 tttttttata acatcaaatc cacgtagatt tttacaaaca aaaataaata aagtcggatt
    61621 tttctgataa ttcaacgcaa aaaagcgaac aatttttcaa taaatcagtc ttctaaaata
    61681 gataacctaa aaaaagcgaa caaacaaata aaatgactgt ccttcattca ctaaacatat
    61741 ttttattttt ttatattgtt aaaaattcgc aatttatttt ttaatagaat tatctgtttt
    61801 ccaaatttta taacataaaa aacctttttt aacggcattt atatgctttt tcagaaatta
    61861 actgatgatt tcaaaaagaa aacatgtcat aatatttccc atattgtgca aaaaaataca
    61921 aggcggaggc tctactatga ttgaagaata tattgagaaa aatattttaa gacagctgtt
    61981 tttatgtggg caattctatg taaataaaga agtcaatcta gaaaagctct ccaatctcct
    62041 gcatgtttgc aaaaccactt tactcaatga tatcaataac ataaaaaaag aatttgaaga
    62101 acagatcgct tatacacatc gggaaaagga ccgttacact ttatattttt cagaacatat
    62161 acctcgatgc aagatcatgc agcaattgtc tcaaaattcg ttgtttttaa aaacttgtct
    62221 gctttatttg gaagaagatg aacctgatta tcttcaatta actgaatgtg aattcatctc
    62281 tgtcagcaaa gcttattcat taaaaaaaca agtattagct tattttaatg actgcgggat
    62341 cgaaatcgac cgctactccc ctcgattcac tgaaatggaa agacgtctgc tgcttcttaa
    62401 tgtgtcgtat cgtttaggcg gttttaattc ttgggagcta cctgaatcgt tttttgaacg
    62461 tgccgatcgt ttcattgaat ccgtaacgga aaatagtggc agattttatg ataaagaaaa
    62521 taaagaaatc ttatcgattg gttttgctat cagtttccta cgccagcaag tgtgtgctgt
    62581 gacaatagat tcaaaattta tcgaagaaat caaaaaacgt cctatttaca attatgtcga
    62641 atcagcatgg gaaaacactg atttccaaac ctattataaa aaagaagaat tcgcctttat
    62701 tttgacacta ttcaatcttt gtaattatgg tttccattct tatcagttga ttgcggaaga
    62761 ctttcaacag ctacaccaag tgtttattga caatactccc gaaataaaag aactagttgc
    62821 tacctttgaa tctcacttca atcaagaatt attcggaaac caaccgttcg aacgtgcgct
    62881 gattcatctg atgcgttcgg cttgggataa ctatcaatta ttcatgccag aaaaatttta
    62941 tcttttaaat gaggaacaga caaatttata taaagaagtc cagacaattt tttccagctg
    63001 gtccagccag ttaccttatg atctacggtt gaatcctaat tgcatgcggg cttttgtgat
    63061 cgaattgagc ggaattctcc gtctgacaaa agaacatctg actatctata tcgtcacaaa
    63121 ttcggatgtt cattatctga tttatcggga agccttggaa gctgtaacta ctttcgattt
    63181 tcaagttgca ccaacaattt attcaagtat atctgatata aagaagtatg cgcagcagtc
    63241 ctcaaaccgg gtattatgtg aacgtacatt atatacacca gatgcggtcc aatatgaaaa
    63301 tattattcct atttcgatca atacgatcga tcgagctatc atttcagctg tgcaaaacaa
    63361 ataaggggct gtgacaaaaa tcatgtcaca gcctcttatt tgttgaagat gcccatttct
    63421 gtaacaatct cttgatacac gtcaggctca caacctcact tattttggac atctacgggt
    63481 ccgatctctt tatttaaaaa ataagaaatg atggttcgga taactaccaa cgccgctagt
    63541 tggaaaatat cctgcaaggt aggtttgata atcgattcga tgatcccagc tgaaacaaga
    63601 atttccaaac ttagaagtat atagcctccc aacatctttt taatagcatt gttctcgctg
    63661 actcggtcgc tttgcacttt tgtatggaca aataaatatt tcaaaaaatc cttgattgat
    63721 agacaaacac cccaaaccaa taaacagata gcaaagatat caagtcccag tacaagtttt
    63781 tcgaaatatg gaagaagaaa ctgcatcaac tctgtcgtca tcctacctct cctcttcttt
    63841 gtttttcttt gtcttctatt tcctgattca agaaataaga aatgactgtt cgaatgataa
    63901 taataagtgc aagcttcaaa atatctgtcc aagtcggctt gataactgac tcgatgatat
    63961 cagcaacgac tagtacttcc aagcttaaca aaatataact tgctagcagt tttcttgtat
    64021 ctgcattacg agtattacgt tctgcatagt ttttcttgac atgagaccaa tcaaaaagtt
    64081 tgaatagaac aagaacgatc ccgacaatta agataccgat agaacaaata tttaaaatag
    64141 caatgatcca ttctagaaat tcaattaaat ttgagcgaaa catatacgct acctactttc
    64201 ttttaatttg ttcctattct tttattgtaa aagaaagtta ccttgttcgt ctatttaaaa
    64261 gttgttctaa tgataacggt tcgcttaaat ttttcttttt cactctccca tttttctccc
    64321 tccatccata aatcgtggaa gtatccaaaa caacgtagca agttaaaata aggcttagtc
    64381 cgtcatcagc ttttcaaaga agcactgtct cggtgctttt tttgtaccca aatttctaaa
    64441 aatagaacca tacacctcct caaatctttt cttcttacct accctatttt tatttacagg
    64501 aaaatcagac acttcttctt ttttgtcaaa atttcctttt tcttctcgtc ctatcatttg
    64561 gcattctaat aaaaacgaac tatccttgga tatagaaaga gaaaacaagg aggcgttttt
    64621 catgagtaaa aaattaatca aagtcggcat cggtttaggt ttgcttgccc ttggcgctgc
    64681 atatctagga aaaaagacag gactattcga agatgacagt catttatatg atgaattcga
    64741 atcaatctag catcctattt agttgaatca ctacggacat acttggaaga cattggagga
    64801 atcacaatga gaaaaagtaa agcaataatg attggtgccg gtattgccaa tatggcagcg
    64861 gctgtttatt tgattcaaga aggcaaatgg aaaggggatc agatcacctt ttattcattg
    64921 gatgatcacg gttcaaatga tggtgcaccg accgacactg tagtggatga atattggaat
    64981 aaaaaccatc cattagaaaa ccaaaaaggc tatattgctc gaggcggtcg catgcttaat
    65041 taccgtacct atgtagattt gatggatctg ttaagtcgaa taccttctgt tactgagcca
    65101 gggatgactg ctgaagaaga tacgagagat tttgatgcaa aacaccgaac ctttgacaaa
    65161 gcacgtttga tggaaggtgg caaaggaatc attgatggcg gaaaactggg attcaataat
    65221 aaagaccgta ttcttctgac taaactgatt gctatgcctg attcagaaga agaaaaacta
    65281 gacaatatca ctatcgaaga atatttcaaa gatgatccac acttttttga aacaaacttc
    65341 tggtttatgt gggaaacaac atttgctttc agaacacgta gttctgctca agaattgcgt
    65401 cgctatatgc atcaaatgat ttatgaattc actcaaatcg aacatctagt gggcgtcaat
    65461 cgaacacgtt acaatcaata cgaaagtatt atgcttcctt tgatcgagta cttgaaagaa
    65521 caaggatgca aaatcatttt gaaccgccgt gtcactgact gggaattcaa agaaacaccg
    65581 atgcaagatg aaatcactgt gactggtttg aaaattacca atacactgac tcaagaagaa
    65641 gaatacgttg tggtcgatga agatacagca gttattttca ctaatgggtc cattacagat
    65701 tcagctactt taggagatta cgaaacacca gctgtagaaa atatggatta tggtgcagct
    65761 tctagtctct ggaaaaaagc cagtgaacgt ttctacaact tgggaaatcc tgacaaattc
    65821 tttgctgatc gagatgcaag cgaatgggtc agctttaccc tgacgacgaa aaaccatttg
    65881 ttgttgaatg aaatcacccg tatcacgact caagaaccag gaaatgcctt gaattcattt
    65941 atttcaacca caccgatcac gccgttaggc caaaaagatg tcaatatgtc tatcgtcgtg
    66001 catcatcaac cgcattttac gtctcagaaa ccaaatgaaa cagttatttg gggttatttc
    66061 ctttatccaa gacgacgtgg cgaatttgtg gataaacagt atattaaaat gaatggaaaa
    66121 gaaatgctag aagaactgat tggacaactt tcaaaagtag atcctggacc agtgaatatt
    66181 cgtgaaaaag aaacagaaat tttcgacagc gtaataaata atatccctgt ctatatgcct
    66241 tatgcttccg cgttgttcaa taatcgtgcc aaaagcgatc gaccaaaagt cattcctaaa
    66301 cattcgacca atctggcctt tacaggagaa tttgtcgagc agccttatca gatgatcttt
    66361 actgaacaaa gtgctgtacg ttctggagaa atcgctgctt tccattttgc gggtattcct
    66421 atgtcccgtc ttgtcaaaac accgcgttac gacaaagata ttcctactct agctcgtgcc
    66481 gcaaaaaaaa tgtttgaata atcaagaggt tgtgaaaaag ctgccctgca tcaagtaata
    66541 agaacaacca ggctaaaaca gcttcttatg tttttgattt ggttggactt attaccgcag
    66601 atgcaagctt ttgaacaccg tttaccaaga ggttgtgaaa aagctgccct gcatcaagta
    66661 ataagaacac ccaagctaaa actgcttctt atgtttttga cttggttgga cttattaccg
    66721 cagatgcaag cttttgaaca ccatttacca agaggttatg aaaaagctgc cctgcatcaa
    66781 gtaataagag cagccaagct aaaacagctt cttatgtttt tgacttggtt agacttatta
    66841 ccgcagatgc aagcttttga acaccgttta ccaagaggtt atgaaaaagg cgtttagttt
    66901 cgagtatgaa gaaaaatttt gtgaaaatgg ttcctcacgt ttttgcataa atttgactta
    66961 ataccgagaa actgatccct tctgtcataa cctcttttta tttatgtctg tttctttttg
    67021 aaaacaacta ttttttcaac gtttactctc ttgccaatcc aacatcatct aacggataca
    67081 actatttcaa tgattaccat tacactaaaa aatcggaaac acacctctcc gaacacaaat
    67141 acataagact atagaatgtt tcatttaaga aaaaaagcgt ttcattatca aaaaggtaag
    67201 atctccttta aaatgaaatt atctgtagta ctaataatgc agacaatttt atgaatctga
    67261 aaggagcatc tccaatgaaa gcagtcactt ggcaaggaaa acagaaaatg gaaatcagaa
    67321 acgtagatga tccaaaaata ttagaaccaa cagatgcaat catccgtatc acagcaacag
    67381 ccatttgcgg ctccgatctg catctttacc atcatggtga agcagttttg gaaaaagggt
    67441 atgttgtagg acacgaacca atgggaatcg ttgaagaagt gggatctcaa gttcaaacat
    67501 tgaaaaaagg gcaacgtgtg gttatccctt ttaatattag ttgtggtcat tgtcatttct
    67561 gcctgaatca catggaaagc caatgtgatg aatcaaatcc agatcagtta tatggcgggc
    67621 ttttcggatt tggcaagttg aacggtaatc attggggtgg tcaagcggaa tatctaagag
    67681 ttccttatgc agactctact tcatttgttg taccagataa tgatcttcct gatgaaaaag
    67741 ttttatttct atcagatatt ttgcccacag cttattggag cgttgaaaac gcaggagtaa
    67801 aaaaaggcga tacagttgtg attctaggtt ctggtccagt cggtctattc gctcaaaaat
    67861 tcgctgttat ggctggagca gagcgcgtaa tcgcagtaga tccagtacag caccgtctag
    67921 ataaagcggc taattacaat ggggttgaaa cttatttctt agaagacacg gcacaagctg
    67981 gaacagaatt gtatgaactg gctaaaggtg gcgcagatgt cattatcgat tgtgtaggaa
    68041 tggacggatt agagcctgtc aaagaaaaag cgaaaaattt agtaagctta caaagcggca
    68101 caatctctcc attacagatg gcatcgcaag ctgtcaaaaa atttggaaca gtccaagtaa
    68161 ctggtgttta tatgactcca gcttcttctt acccgctgca agaatttttt atgcgggata
    68221 tcgctgtcaa gcatggacag gcaccaatta tccatctaat gccaaaaatt tacgcaatga
    68281 ttgcagaagg actattcgat cctacacaaa tcattactca ttcgctgcca ctatcagaag
    68341 cagcacaagc atatgagatc tttgacaaaa aagaagataa aaatataaaa gttgttttga
    68401 aaccttgaat tcagtaaaaa atacaggtga ttttctttat gcccaaaatc aaacgaaata
    68461 cccatgagat cgaaatagga aaagaagaag atatcgaaat acgaggacgt cgcttccgct
    68521 tctatttcca aaatcgttac acattgatct cactggctgt cgatttatta accgggattt
    68581 tctatatttt tggaagcctt gcttccttaa ctaaaatccc cgatcgatat ggcacctatt
    68641 tttatttggc tggtgctatt ttcttgacga ttcgtcctat tctcagaatc gtaaggaaca
    68701 tttttattta cgacgaaaaa aaagcaatga agagaacaag caaaaaaaaa gaggcatgag
    68761 aatttttcaa atctcatgcc tcttttttca ccctatcgta tcactttgat acagacgagc
    68821 ggtcgtccca ctttcttcct tgaccattgt caaaaatgtc cactcgtatc gttcataaaa
    68881 cgtggtatga tctgtaatta agtaaagttt ttcgtaccca agttgatgca tttcttttct
    68941 gatttccgct aatatccgct tggctatccc ctgcttacgc ttttccggtt caacaaacag
    69001 ggcacaaaga tttggtgtca gatcagggcg gttatggaag tcgttttcaa tgacgcccgc
    69061 tcctccgacg atggtttctt tttcatctaa gaccacatac cattgaggaa tactttcctt
    69121 attagcgatt ccagtacgaa tactttcctc atacacaaca gcaggaactc cccattttga
    69181 tgaaaaccaa ttcgcgcttt gttttactaa ttctgggtgt tctcttaatt tgatccagtt
    69241 atatgtaacc aatgtttaaa cctccgacta aaataaaacg tttacaaaaa ttatacaagt
    69301 ctttatgaaa attagcaatg acaacaatag tgatgtaaaa aaaaaaacgg aaaacaatca
    69361 cttgttctcc gttttttgat tgatcaagca tctaaagctt cttttcttct ttcttggatc
    69421 gtagctacct tgacgaacgg tagatagatc aaaatagaaa gaaccaaatt gacagcggct
    69481 agtacaccac ctgcaatact ttttgttgcc aatacaccgc caataattgg tggagttacc
    69541 catggaggca taacggtagc tgctggcact aaacctgtag aagtcgcaaa gtaagcaaca
    69601 ctaactaaga ccattggtgt caaaataaat ggaatgaaca tgatcgggtt caacacgata
    69661 ggtaacccaa acatcgttgg ttcattaata ttgaaggaca cctggcgcaa tcgacaagtt
    69721 tgttacaacc atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc
    69781 taaagttgca cctgttcctc ctaagttgac aaagctgtca aagaaaggtt tgttcacgat
    69841 aaacggtgcg ctatgcccag ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt
    69901 gattgtttgc atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga accataagaa
    69961 tggtgtgata aatgcaagca gtaaggcaga tggataagag tttgcaagtc ccataaatgg
    70021 ttcttggacc actgtataga aagaacctac gatatcatca acaccgaatg cagcaaaaat
    70081 tgcagcaact aaagcaaacg cagagatagt gatcattgct ggtagtaatg aagcaaatgc
    70141 ttttgcaact gccggtggca caccatcagg cattttgatg atcaattttt catttccgct
    70201 taaacgtaca aagatttctg ttgaaataat cccaacaata atagcaataa acaaaccgtt
    70261 tgagctcata cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc
    70321 ggaaacaccg tcttttcggt agccgttagc taaatgataa gcaagcaaga aagcaatcaa
    70381 gacagaaaga atggcaaatg taccgttcca agcagcagcc ccgaatcctt tccatgattc
    70441 accaccaaaa attgagttca tcaattcttg gaacccggga atcggtaagt tattgatcat
    70501 tactgctaat gctcctaaga tcattaacgg catactcacc ataaatgagt cccgaatcgc
    70561 aactaaatgc cgttgtgcac caatttttga tgctacaggt ataaaatgtt tctccataaa
    70621 tgcaacaaat ttatccataa atcttccctc ttttctttac tgtagattac gcgttcaatc
    70681 gacgatacag atcaatgatc tcttttgcta aatctgtaaa agctatagat gtcatcagat
    70741 gatcttgact gtggaccgtc aaaagcgtga cttcaacgtg atttccttgt gcttcttgtg
    70801 tcagcatctc tgtttgagag tgatgtgctt ggactaaaga ttcctctgca tctttgattt
    70861 tttcatctgc taaagtgaaa tcaccttttt tcgcagcagc aatcgcttcc attgcatcgc
    70921 tttttgcatt tccgccaaac atgatcagac ccatgatggc ttctagattt ttttgatctt
    70981 ccatttattg tatcctccga taatttttat tatttgttta ttagtttttc tgcttggtcg
    71041 agtacttttt caccattcat catgccatag tcagccatat tgattacatc taaaggaatg
    71101 cctttaggtg ctagcttttc agcaaattga ttttgcataa agcgtacttg cggtcctaaa
    71161 agtaaaacgt ctacattttt agattctagt tgattatccg catctgaagc agatacagca
    71221 aagatgtctg cttccattcc ttttgcttct gctgcctttt gcatttttgt gactaggaga
    71281 cttgtactca ttccagctga acatacaagc atgattgttt tcttttccat tttaaacacg
    71341 ttcctttcta tacttacact tgtatataag caagtagcgt gccaacttta aaagcgcttt
    71401 aaaaagttga tatcatcaca tttaaggtct ataccaagtt gcatacacac taaaaaagaa
    71461 agcgcacact aaacacacaa attaattttt attacctttt ttcttttaac gtgcacaaaa
    71521 aaagttgtga cacaaaactt gtcacaactt ttttcaaata aacggtattc aaaagcttgc
    71581 atctgcggta ataagtccaa ccaagttaaa aacataagat gttgttttta ctttgctatt
    71641 cttattactt gatgcaggac agctttttca caacctctca ataaacggtg ttcaatcagc
    71701 tgaccctggg tattagctca aaacgctgga ttcacaacct cttttatttc aaataaccag
    71761 taaatacaat gaacatctac aaaaaacttc tatttattta tagatttcgt caggcaaatc
    71821 caattctctc ttatcaatca aagtctgata ccacgaagca gattttttca atgttctgct
    71881 tcgttcatcg ttcaattcga ttcgaactaa tccatatcga ttcttaaatg cattcattgg
    71941 tgacacacag tcagtgaatg cccataacat atagccttcg caatttgcgc cttcttctgt
    72001 tgctttgatc aagtaatgca aatgctgtcc gataaattcg atacggtaat catcttgcac
    72061 gattcctttc tcatccatat actgttcttc atattctctt cccataccgt tttctgttat
    72121 cagccaaggg atattatgat aattttcttt tagatacatg gctatatcat acatgatttt
    72181 cggatagatt tcccatcccc tggaattatt cattttcttc ccaggtaaat caaagacttc
    72241 ataatatcgt tcaggatgga aaggtgtctc ttcattccat tgataacgag gggcgcgaac
    72301 gcgtttagga taatattgat tgattccaag gaaatctact gtatgatgct gaatcgtttc
    72361 taaatcctct gttgcaggat cgaaataaat cgattgtttt tgacacaact ccaggaactc
    72421 ttctgtgtag tatcctttta ccatcggatc aaaaaatact cgattataaa acaaatcata
    72481 catataagca gctttttggt cttctggaga attggatcga gcatagacca tttcaggatt
    72541 taaaatacag ccaatccttc caccataatt tccgctgcgg taaatctcta ctgctttagc
    72601 cgttgctaaa actttatgat aattccacat catccacttt tttgtgtttt gttcatgcgg
    72661 ccagcgaaca gcatccaaat agcaacgcgt ttggggaacg attggttcgt tgaatgtaaa
    72721 ccagtttttt accctatcac cgtaacgatc aaaggcaatt tgagcatact tagcataaaa
    72781 atcaactact tttcttgaag accagccatc atatttttcc aaaagaaaag ctgggacttc
    72841 ataatgttcc aaacaaatca tcggttctac gtctgcttcg atcaaagagt cgatcatttc
    72901 acttatatgc tgagcatatt cttcatctac tatacagttc tcataatcag taaaaaaacg
    72961 agcccaattg atagaagtcc gataatgtgt cagatggatg gatttcatca gatccacatc
    73021 ctgctggtat tgttccataa aattagttgc tacggctggg ccatacccat tatgccaaac
    73081 aaaatgttca tttttatacc agctatctat aaacgaatcc tgtccttctt tttttccttt
    73141 ccaaccttcc gtttgccaag cagaagatgc agcaccaaga ataaaatttt ttggaatagt
    73201 aattttcatg atttcctcct gttttttaga tcccatcatt ttccacacga tttgctactt
    73261 ttacaaatgg cagatagatc aaaatagaaa caataataca aacaagttgc gtaataactg
    73321 caccgatatt tcctgctgtt gccagataag cattgacgat cggcggcatt ggccaaggga
    73381 ccattacaac tgctttcgcc gcaaatccta aagcggttgc aaaataacca atcgttccag
    73441 tgataagagg cgttaagata aacggaatag ctaaaattgg attcagcatg atcggcatac
    73501 caaaaataac tggttcattg atgttgaaga tcccaggagc aagggataac ttggtgattt
    73561 gtttcatatc ttcccgtttt ccaactaaca atactgcaat cagtaaaccg atcgtgactc
    73621 cagacccgcc catactcata tacatatccc aaaatggcat agtaataatg ttcggtactt
    73681 cttttccagc ttcaaaagct tccgtattta cagcaattgc cgctaaaagc aacggttccc
    73741 gtatcggctt caccatttga tttccatgga taccaatcac ccaaaagact tgcgcaataa
    73801 acatcaatag caaaataccc ggtaaccctt gtacgacacc ttctaatggg cgttgtacga
    73861 cattgtaaat gatatcataa aggtacattc ctgtaagttc tttgatgata aatcccgcag
    73921 ccgcgatacc cgatacagtc agaatcgtcg ggaataaagc agaaaaacta gcagaaacat
    73981 tcgttggcac ggtatcaggc attctcagct gtagtttctt ctgtttcctc aaccagcaat
    74041 aaagttcaat agaaaggatg gagaccaaca ttcccaaaaa taaccctttc gtatctgtat
    74101 attgtttagc caatacgttt tctactataa cagtctgatt ttcattcact aattcataaa
    74161 cagttggatt aacagataaa taagacatca ctgcgatgat accagggaat acaccatcca
    74221 ctttattcag cttggctaat tcgatcccta tcagaaaaac agcatagatg gtcaagaaac
    74281 ttagtgtgac atagctgatg gcagatgcga taggctttaa ttcttctaaa aaacgcaaga
    74341 aacttatctg tgctaagcca ttttccgagt caaagaccat tgctgaaaac aatgtgccaa
    74401 aagcacccgt aataattacc ggaatcaatg cagcaaatgc gttttttatc accatgatat
    74461 accttaaatt attgattctc gttgccacgt tccctaaaac attggctaat ttatccataa
    74521 aactcattcc agatcccctc attcctgctt cttctccttg acgtcatctc tttttgtcta
    74581 ttagtcagcg cttacatttc gatgaacaga aactatttac tcctcttttt taccaaatat
    74641 aaaacaaaaa ttcatctgat gtatttatca taaaatacat cagatgaact gtcaattagt
    74701 ttctttttct cctattattt tctgtaattc tctccgattt attgccatat ggacagtcat
    74761 tgcatcaaac gcagcaagtg cattccgcct ttcgatggcc tgaacgatct ctgtatgaat
    74821 atcgatcgtc tcgattttca gatgctggat atcataattt ttattaaaca aagcaattga
    74881 ttcattaatg attgggataa tatgcagcaa ggctacgttt ccgctagctt ctgcaatcat
    74941 cgtatgaaaa tcgatgtcta attgaacatg ttcttgtgtg ccttctcgaa aagaagtttc
    75001 aatcttttgc gttaattttt tcatttggac gatttgattc ttcgttgcat attccgctgc
    75061 caaacctgcc atcttaggct ccaataaata tctcagttca aataagtctc gtatcatccg
    75121 atcctgatct tcaatcaaag aaaaaccgag tgggtcattg gcaatccctc gcttatcact
    75181 gacaaatgtc cccgctcctt gccgaacttc aaggatattc ctggaagcta gagcccgcac
    75241 agcttctcgc accgtgcttc gccccacctc taaataatcg gacaattcat attcattcgg
    75301 cagtttatct cctacttgca actgcatttc ctttaaatat ctaaggatct tgtcagtagt
    75361 tacttctact agggttttat tttcttccaa accacatacc tccttttcat ctgatgtatt
    75421 ttttcgtaat tattataaca cgtttgaatc atctgatgat tttttgtata caaaattgat
    75481 taatccgttc atagacatac aaacgaagaa gatatttacc ataaaaaaga ctaggataaa
    75541 attcactcct agccttcgat catttttatt ttgaacgaca aaaaatatga tgttcaataa
    75601 cagacgatct tcattcgatt cttgatgtca tcttttgttt tttttaatat atggataaaa
    75661 agtttgatta catcgtttct attctagaat ttggtcgatt ctcaattctt cttctggtga
    75721 gaaatctaaa ttatccatca ttcgaacact ttcttgtaac tgacttaacc gacttgctcc
    75781 gaccagtaca cttgtaacag atttttgtcg caaattccat gcaagggcca tttgcgctaa
    75841 tgattgtcct cgtgatacgg cgattgtttg cagtgctttg attttttcca gagttgatcc
    75901 aacttgttct tctgaaagga atggtatttc cttacgatgt gctctagaat cttcaggaat
    75961 accatgtaga taacgatttg tcagcaaccc ttgagcaagc ggactgaacg tgattgcccc
    76021 tagcccttct tcttctaata ctggagatag atcgtcttct agtagtgcac gagaaaacat
    76081 attgtagcgc atctgatgaa taatgaacgg tgcttccttt ctttttaaaa tttcagtcat
    76141 tttttttgta tcttctccat tatagttgga tataccaata tataatgctt ttccttgtct
    76201 tacaagttgc atcaaagctt ctgctgtttc ttccaaaggt gtatcagggt ctgggcgatg
    76261 atgatagaag atgtcaacat aatctagccc cattctttgg agactttggt cacaacttga
    76321 aatgatggat ttacgagagc cccattcccc atatggccct tcccacatat gataacctgc
    76381 tttgctagaa ataatcagtt catcacggta ggcttgaaaa tcttctctaa aaatacgccc
    76441 aaagtttttc tctgcagctc cagcagggcc tccataatta ttcgcaaggt cgaaatgggt
    76501 aattcccatg tcgaatgcgc ctcttaaaat ctctctttga ttatggatag gatcataatc
    76561 accaaaattt tgccataatc cgagagataa aatcggtaat ttcaaacctg aatgaccgga
    76621 tttacgatat tccatttttt cataacgtgc actatctgca atatacaatt tttctcctcc
    76681 tcatcaaatc tttttaaaac gctttctttt ttctattttt agtttactac attttaaaga
    76741 aaaggagtta atcaaaatga ttttttcgta tatttttttg ccatttgttt tttactcgtt
    76801 gatagatcag aaattgatta cgtgcttgct ggattttttt ataacgtttc ggttgttttt
    76861 tgtaaaattg ctgatgatag ttttctgctg gccaaaacgt accggctggt tcgatttttg
    76921 tgacgattgg ttggtggaaa gttcctgaac tgtctagttt ctgttttgat tgttccgcta
    76981 attctttttg tcgttcgcct tgataaaaaa tcactggacg atattgcttc cctctatctt
    77041 gaaattgtcc aaatgtatct gtgggatcag taatttgcca atagattgtc agcaactcgc
    77101 tataacttat ttctcttgtg tcataaatga tctccacagc ttccacatga cctgtgtaac
    77161 caccacttac ttgatcataa tttggttttt caacatgtcc gcccgtgtat cctgacaaaa
    77221 cagataggat cccttttttc gattcaaacg gctcgaccat acaccagaaa catccccctg
    77281 caaatactgc acgttcttga tagtcagcat cttgcatggc atgcttggaa aagtcatatt
    77341 tttgctcctt atcaaatcct tccgtaatca ataaataaaa gtccattaca tcaggcgtca
    77401 gattcattcg gatagctaat ggacgtagtg ttgcttctag ttttgataac tgttctttaa
    77461 cggatatatt ttctcttatg tcattctttg tctgaatcaa tacttttcgt tcccaatctc
    77521 gtgtattcgg attcaaaatc agattataaa gtgtttgaat gaatatttgt tcctcatcca
    77581 tagattctcc tcctttccga agaagacaag ctagtgactt tagctgtaat ttatcataaa
    77641 gtgaggaaat aagcgattac ttcatccccc tacagatttt tcgtataaaa aagagagaat
    77701 ccttatcgac agattctcct ttttaatcaa tttattttat aaatgaaaag ttaatttacc
    77761 ttttatggaa aactatttta aaaaataaac ataaatatgc agttaatgta acaagataag
    77821 aaataatagt cgttactgta taacttgtgc ttactttaat atcagcaact cctttgactc
    77881 cgcttatttg taccaatcca ttagcattca cctgctcctt tacaggttga tgatttattt
    77941 ctacattcgt tcctaaataa gcatatacag gaagtgtgat tacttggctc ttctcattag
    78001 ttactctata tatgatagaa ctaccagttg ttttataagg aaggtttacc cattgactgc
    78061 caatctttgc ttcgtgtttt attatatgct ccttattctc caatgaagcg ataggagaat
    78121 aatcatataa aaaataatcc attcctttag tggtatacgc ctctactgtt tctttgttta
    78181 caacaatatg tcccggctga gaaattattt tttgattgaa atttttttta ctagaaacag
    78241 ttaaagtgat taataacaaa acagtcataa ataaataaaa tagttctctt gtcttattgt
    78301 atcttctatt tttgaaaaat atcatcgtta atatcagaga agagaatatt atttgcaagc
    78361 ttaagatccg ccaaggaaat tgtaacaatt tggctggcgt attttgcaga agataccatg
    78421 gcaccaaact agttgtagct agccaagtca aacacgtacc ataataaatc tttttttcta
    78481 tgtttgttaa ttttttaaat aaaatcaggg gaatacataa agataacaga ccaactagtc
    78541 ccattgagta agtagttaag tcgttgttca tagcttcagt cagactatcg aacacattag
    78601 atgcatgagc atataaattt gtcacgctag gtttgttgat tttttggtag agcatttgtt
    78661 caaacatcgg ataccaaaaa gcactcgtca gaaccaatgt cattcctgcc gcactaaata
    78721 attttttaaa tatagcaata aaatctgcat tcttgaaacc tttagaaacc aaacgaataa
    78781 aaatgataat taatgctgta ctcattaatg ttgatagtac atggctgtac actagcaaac
    78841 tcatactcaa tgctagcttt acagacggat acttttcttc ttttccagag atgatttgat
    78901 aagcataaaa taatacaggg ataacaagtg ttattgcgat agcttcggca attgcggaac
    78961 gatagtagat gtctactgtc cgataagcag agaaaatata gagacaacta aataaaaatg
    79021 ccgctttttt ttgttttaaa aaccgctcgc cataatgata agctacgagt gttgtacaca
    79081 agttcaataa ccaaacgtaa ataatatagc ttacaatcaa attttttgtc atccaatata
    79141 acattacagc tggaaaaaaa gtcagaaagg gataaaaata atttacacca tatccagtat
    79201 aattgaatgt ctcataatta atcggactgg taaaaatagt cgataacccc ttgattcgag
    79261 ataagtgaaa agaaagatct ccagtggtat aaatactctg tgtatttttg aaaaagatga
    79321 aagaatatat actactaact ataattaatc cactcaatat tactactttt ttatttattt
    79381 tcattcttct tgtttatctc ctttttagtc acatatcgag aatctttcaa cttattaggt
    79441 gcaaatcgtt taaaacttga atacaccact aaacaataag tcagaatact gatccataaa
    79501 gccatgagag cagttggagt atattttgtt gtaatttcta tcttattttc tccagcattt
    79561 acatccacat tcactaagcc atgtttttta taagagtcat ttacgacttt accgtttact
    79621 tttacctgtg tacctaaata agcatatact ggtactgtca ctttttgctt tttgttgctt
    79681 gccactgtgt aagtaatgtt attatctgca gctttatact tccctttttc ccacgattct
    79741 cctactttta cttcatgttt ttctaagtga ggcctttctt ttatcgcttc tgttggggcg
    79801 taatcgtata atcctcccat atctgatgtt gtataacgtg ggagtgtttc ttcattgata
    79861 acaatatgac cgtgttttga ttggataact tttgcgtaat tttcttttgc tgctatagac
    79921 gtgacgagta gaaacaccac agtagcgcca atgattaacc atgaatattt tttattcata
    79981 gtctttttca taaaaacaag cgttatgatc attgaagaaa aaaagatttg gatacctaag
    80041 atacgccaag gaaactggag caagcttatc ggtgtttttt gaaacaaaaa ccatggaaat
    80101 aaattagtta cgcataccca tgtagaaact acgccaacat agatgatttt ttcttttttc
    80161 tccatttctt tcagtatgaa taaaggaaaa atcaacgcaa ccaatcctaa taaccccata
    80221 gtgtatgttg taatatcgtt atttaacgct tgaatgatac tatctgaaat agaaagtgct
    80281 tctagctgca aatctgtttt gaagggactg tgtatttctt gataattcat ctgctgcaac
    80341 ataggatacc aaaaatagct agttaatgca caagtcaaaa aaacagcctt tactaaattc
    80401 acgaccacaa attttatatc gttttttatt tgcttgctta aaaacaaacg aactataatc
    80461 atacaagcaa tcaatgcact acacaatagt gtagttaaga catgagtata cacaagtaga
    80521 cttatactga cagataaagc gatgactttt ttttctctat tgaatatcaa tccataagca
    80581 taatataaaa cagctgggat aatcgtaaga gcgattgctt ctgcaattgc ggatcgataa
    80641 tagatatcaa ctgttcgata agttgcaaaa gtatataaac aactaaataa aaaagcagca
    80701 tctatctttt taaaaaactt ttctccataa taaaaac
//
LOCUS       DARPZJ010000007        80102 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.007, whole genome shotgun sequence.
ACCESSION   DARPZJ010000007 DARPZJ010000000
VERSION     DARPZJ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.007"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            374..3181
                     /locus_tag="SLE23_000592"
     CDS             374..3181
                     /locus_tag="SLE23_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8467518.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3372..3863
                     /locus_tag="SLE23_000593"
     CDS             3372..3863
                     /locus_tag="SLE23_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8467519.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3966..4955
                     /gene="manX"
                     /locus_tag="SLE23_000594"
     CDS             3966..4955
                     /gene="manX"
                     /locus_tag="SLE23_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEI8467520.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4988..5791
                     /locus_tag="SLE23_000595"
     CDS             4988..5791
                     /locus_tag="SLE23_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEI8467521.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5812..6726
                     /locus_tag="SLE23_000596"
     CDS             5812..6726
                     /locus_tag="SLE23_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEI8467522.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6809..7183
                     /locus_tag="SLE23_000597"
     CDS             6809..7183
                     /locus_tag="SLE23_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEI8467523.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7322..7567
                     /locus_tag="SLE23_000598"
     CDS             7322..7567
                     /locus_tag="SLE23_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8467524.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7739..8803
                     /locus_tag="SLE23_000599"
     CDS             7739..8803
                     /locus_tag="SLE23_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEI8467525.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9049..9474
                     /locus_tag="SLE23_000600"
     CDS             9049..9474
                     /locus_tag="SLE23_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8467526.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9467..9916
                     /gene="nusB"
                     /locus_tag="SLE23_000601"
     CDS             9467..9916
                     /gene="nusB"
                     /locus_tag="SLE23_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEI8467527.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10013..10867
                     /locus_tag="SLE23_000602"
     CDS             10013..10867
                     /locus_tag="SLE23_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEI8467528.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10868..12205
                     /locus_tag="SLE23_000603"
     CDS             10868..12205
                     /locus_tag="SLE23_000603"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEI8467529.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12210..12434
                     /locus_tag="SLE23_000604"
     CDS             12210..12434
                     /locus_tag="SLE23_000604"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEI8467530.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12436..13326
                     /locus_tag="SLE23_000605"
     CDS             12436..13326
                     /locus_tag="SLE23_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEI8467531.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13335..14153
                     /locus_tag="SLE23_000606"
     CDS             13335..14153
                     /locus_tag="SLE23_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEI8467532.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14260..14709
                     /locus_tag="SLE23_000607"
     CDS             14260..14709
                     /locus_tag="SLE23_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEI8467533.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14727..16409
                     /gene="recN"
                     /locus_tag="SLE23_000608"
     CDS             14727..16409
                     /gene="recN"
                     /locus_tag="SLE23_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEI8467534.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16464..16580)
                     /locus_tag="SLE23_000609"
     CDS             complement(16464..16580)
                     /locus_tag="SLE23_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEI8467535.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16653..17609)
                     /locus_tag="SLE23_000610"
     CDS             complement(16653..17609)
                     /locus_tag="SLE23_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEI8467536.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17780..18148
                     /locus_tag="SLE23_000611"
     CDS             17780..18148
                     /locus_tag="SLE23_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEI8467537.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18319..18750
                     /gene="mraZ"
                     /locus_tag="SLE23_000612"
     CDS             18319..18750
                     /gene="mraZ"
                     /locus_tag="SLE23_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HEI8467538.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18771..19730
                     /gene="rsmH"
                     /locus_tag="SLE23_000613"
     CDS             18771..19730
                     /gene="rsmH"
                     /locus_tag="SLE23_000613"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEI8467539.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19735..20136
                     /gene="ftsL"
                     /locus_tag="SLE23_000614"
     CDS             19735..20136
                     /gene="ftsL"
                     /locus_tag="SLE23_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEI8467540.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20137..22329
                     /locus_tag="SLE23_000615"
     CDS             20137..22329
                     /locus_tag="SLE23_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEI8467541.1"
                     /translation="MSLKNKIRRFMEKKNLNPINNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGIAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22355..23317
                     /locus_tag="SLE23_000616"
     CDS             22355..23317
                     /locus_tag="SLE23_000616"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEI8467542.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23331..24692
                     /locus_tag="SLE23_000617"
     CDS             23331..24692
                     /locus_tag="SLE23_000617"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEI8467543.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24718..25806
                     /gene="murG"
                     /locus_tag="SLE23_000618"
     CDS             24718..25806
                     /gene="murG"
                     /locus_tag="SLE23_000618"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HEI8467544.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25821..27041
                     /locus_tag="SLE23_000619"
     CDS             25821..27041
                     /locus_tag="SLE23_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEI8467545.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27197..28522
                     /gene="ftsA"
                     /locus_tag="SLE23_000620"
     CDS             27197..28522
                     /gene="ftsA"
                     /locus_tag="SLE23_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEI8467546.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28545..29786
                     /gene="ftsZ"
                     /locus_tag="SLE23_000621"
     CDS             28545..29786
                     /gene="ftsZ"
                     /locus_tag="SLE23_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEI8467547.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29803..30480
                     /locus_tag="SLE23_000622"
     CDS             29803..30480
                     /locus_tag="SLE23_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEI8467548.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30494..31093
                     /locus_tag="SLE23_000623"
     CDS             30494..31093
                     /locus_tag="SLE23_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEI8467549.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31108..31395
                     /locus_tag="SLE23_000624"
     CDS             31108..31395
                     /locus_tag="SLE23_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEI8467550.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31444..32226
                     /locus_tag="SLE23_000625"
     CDS             31444..32226
                     /locus_tag="SLE23_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEI8467551.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32247..32954
                     /locus_tag="SLE23_000626"
     CDS             32247..32954
                     /locus_tag="SLE23_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEI8467552.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33216..36014
                     /gene="ileS"
                     /locus_tag="SLE23_000627"
     CDS             33216..36014
                     /gene="ileS"
                     /locus_tag="SLE23_000627"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEI8467553.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36063..37589)
                     /locus_tag="SLE23_000628"
     CDS             complement(36063..37589)
                     /locus_tag="SLE23_000628"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEI8467554.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37604..38251)
                     /locus_tag="SLE23_000629"
     CDS             complement(37604..38251)
                     /locus_tag="SLE23_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEI8467555.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38435..38764)
                     /locus_tag="SLE23_000630"
     CDS             complement(38435..38764)
                     /locus_tag="SLE23_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HEI8467556.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38941..39669
                     /gene="sfsA"
                     /locus_tag="SLE23_000631"
     CDS             38941..39669
                     /gene="sfsA"
                     /locus_tag="SLE23_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HEI8467557.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39685..40698
                     /locus_tag="SLE23_000632"
     CDS             39685..40698
                     /locus_tag="SLE23_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8467558.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40698..41975
                     /locus_tag="SLE23_000633"
     CDS             40698..41975
                     /locus_tag="SLE23_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEI8467559.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42038..44740
                     /locus_tag="SLE23_000634"
     CDS             42038..44740
                     /locus_tag="SLE23_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8467560.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44892..45209
                     /locus_tag="SLE23_000635"
     CDS             44892..45209
                     /locus_tag="SLE23_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8467561.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45239..45559
                     /locus_tag="SLE23_000636"
     CDS             45239..45559
                     /locus_tag="SLE23_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEI8467562.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45667..47127
                     /locus_tag="SLE23_000637"
     CDS             45667..47127
                     /locus_tag="SLE23_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8467563.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47195..47416
                     /locus_tag="SLE23_000638"
     CDS             47195..47416
                     /locus_tag="SLE23_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467564.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47447..47629
                     /locus_tag="SLE23_000639"
     CDS             47447..47629
                     /locus_tag="SLE23_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HEI8467565.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47629..48042
                     /locus_tag="SLE23_000640"
     CDS             47629..48042
                     /locus_tag="SLE23_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEI8467566.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48165..49346
                     /locus_tag="SLE23_000641"
     CDS             48165..49346
                     /locus_tag="SLE23_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467567.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49417..49581)
                     /locus_tag="SLE23_000642"
     CDS             complement(49417..49581)
                     /locus_tag="SLE23_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467568.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49735..49808
                     /locus_tag="SLE23_000643"
     tRNA            49735..49808
                     /locus_tag="SLE23_000643"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49769..49771,aa:Arg,seq:cct)
     gene            complement(49877..51016)
                     /locus_tag="SLE23_000644"
     CDS             complement(49877..51016)
                     /locus_tag="SLE23_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8467569.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(51315..51950)
                     /locus_tag="SLE23_000645"
     CDS             complement(51315..51950)
                     /locus_tag="SLE23_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467570.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(52063..52698)
                     /locus_tag="SLE23_000646"
     CDS             complement(52063..52698)
                     /locus_tag="SLE23_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HEI8467571.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(52732..53193)
                     /locus_tag="SLE23_000647"
     CDS             complement(52732..53193)
                     /locus_tag="SLE23_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HEI8467572.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(53323..53754)
                     /locus_tag="SLE23_000648"
     CDS             complement(53323..53754)
                     /locus_tag="SLE23_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEI8467573.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(53772..54092)
                     /locus_tag="SLE23_000649"
     CDS             complement(53772..54092)
                     /locus_tag="SLE23_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467574.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            54391..55167
                     /locus_tag="SLE23_000650"
     CDS             54391..55167
                     /locus_tag="SLE23_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HEI8467575.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            55182..55385
                     /locus_tag="SLE23_000651"
     CDS             55182..55385
                     /locus_tag="SLE23_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467576.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            55401..55739
                     /locus_tag="SLE23_000652"
     CDS             55401..55739
                     /locus_tag="SLE23_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HEI8467577.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            55726..55905
                     /locus_tag="SLE23_000653"
     CDS             55726..55905
                     /locus_tag="SLE23_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467578.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(55948..56418)
                     /locus_tag="SLE23_000654"
     CDS             complement(55948..56418)
                     /locus_tag="SLE23_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467579.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            56505..57203
                     /locus_tag="SLE23_000655"
     CDS             56505..57203
                     /locus_tag="SLE23_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HEI8467580.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            57381..57722
                     /locus_tag="SLE23_000656"
     CDS             57381..57722
                     /locus_tag="SLE23_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467581.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            57715..58386
                     /locus_tag="SLE23_000657"
     CDS             57715..58386
                     /locus_tag="SLE23_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEI8467582.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            58392..59078
                     /locus_tag="SLE23_000658"
     CDS             58392..59078
                     /locus_tag="SLE23_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467583.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            59081..59830
                     /locus_tag="SLE23_000659"
     CDS             59081..59830
                     /locus_tag="SLE23_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467584.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            59842..60111
                     /locus_tag="SLE23_000660"
     CDS             59842..60111
                     /locus_tag="SLE23_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467585.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            60117..60281
                     /locus_tag="SLE23_000661"
     CDS             60117..60281
                     /locus_tag="SLE23_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467586.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            60274..60573
                     /locus_tag="SLE23_000662"
     CDS             60274..60573
                     /locus_tag="SLE23_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467587.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            60573..60875
                     /locus_tag="SLE23_000663"
     CDS             60573..60875
                     /locus_tag="SLE23_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEI8467588.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            60915..61280
                     /locus_tag="SLE23_000664"
     CDS             60915..61280
                     /locus_tag="SLE23_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467589.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            61770..61910
                     /locus_tag="SLE23_000665"
     CDS             61770..61910
                     /locus_tag="SLE23_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467590.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            61907..62095
                     /locus_tag="SLE23_000666"
     CDS             61907..62095
                     /locus_tag="SLE23_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467591.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            62103..62297
                     /locus_tag="SLE23_000667"
     CDS             62103..62297
                     /locus_tag="SLE23_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467592.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(62330..62542)
                     /locus_tag="SLE23_000668"
     CDS             complement(62330..62542)
                     /locus_tag="SLE23_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467593.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            62667..62870
                     /locus_tag="SLE23_000669"
     CDS             62667..62870
                     /locus_tag="SLE23_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467594.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            62867..63139
                     /locus_tag="SLE23_000670"
     CDS             62867..63139
                     /locus_tag="SLE23_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HEI8467595.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            63140..63325
                     /locus_tag="SLE23_000671"
     CDS             63140..63325
                     /locus_tag="SLE23_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467596.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            63312..63659
                     /locus_tag="SLE23_000672"
     CDS             63312..63659
                     /locus_tag="SLE23_000672"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467597.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            63619..64095
                     /locus_tag="SLE23_000673"
     CDS             63619..64095
                     /locus_tag="SLE23_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEI8467598.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(64241..64969)
                     /locus_tag="SLE23_000674"
     CDS             complement(64241..64969)
                     /locus_tag="SLE23_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEI8467599.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            65017..65295
                     /locus_tag="SLE23_000675"
     CDS             65017..65295
                     /locus_tag="SLE23_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467600.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            65297..65683
                     /locus_tag="SLE23_000676"
     CDS             65297..65683
                     /locus_tag="SLE23_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467601.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            65680..66060
                     /locus_tag="SLE23_000677"
     CDS             65680..66060
                     /locus_tag="SLE23_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEI8467602.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            66172..66624
                     /locus_tag="SLE23_000678"
     CDS             66172..66624
                     /locus_tag="SLE23_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEI8467603.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            66621..68348
                     /locus_tag="SLE23_000679"
     CDS             66621..68348
                     /locus_tag="SLE23_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEI8467604.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            68412..69599
                     /locus_tag="SLE23_000680"
     CDS             68412..69599
                     /locus_tag="SLE23_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEI8467605.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            69571..70140
                     /locus_tag="SLE23_000681"
     CDS             69571..70140
                     /locus_tag="SLE23_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEI8467606.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            70153..71517
                     /locus_tag="SLE23_000682"
     CDS             70153..71517
                     /locus_tag="SLE23_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEI8467607.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            71519..71800
                     /locus_tag="SLE23_000683"
     CDS             71519..71800
                     /locus_tag="SLE23_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEI8467608.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            71778..72104
                     /locus_tag="SLE23_000684"
     CDS             71778..72104
                     /locus_tag="SLE23_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEI8467609.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            72094..72432
                     /locus_tag="SLE23_000685"
     CDS             72094..72432
                     /locus_tag="SLE23_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467610.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            72422..72787
                     /locus_tag="SLE23_000686"
     CDS             72422..72787
                     /locus_tag="SLE23_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEI8467611.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            72794..73420
                     /locus_tag="SLE23_000687"
     CDS             72794..73420
                     /locus_tag="SLE23_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8467612.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            73420..73884
                     /locus_tag="SLE23_000688"
     CDS             73420..73884
                     /locus_tag="SLE23_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467613.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            74079..76388
                     /locus_tag="SLE23_000689"
     CDS             74079..76388
                     /locus_tag="SLE23_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEI8467614.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            76400..77104
                     /locus_tag="SLE23_000690"
     CDS             76400..77104
                     /locus_tag="SLE23_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8467615.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            77101..79860
                     /locus_tag="SLE23_000691"
     CDS             77101..79860
                     /locus_tag="SLE23_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8467616.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            79873..>80102
                     /locus_tag="SLE23_000692"
     CDS             79873..>80102
                     /locus_tag="SLE23_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HEI8467617.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKI"
BASE COUNT        27133 a        13157 c        16845 g        22967 t
ORIGIN      
        1 aaaataaaag ttgtagtgga ggctacgaag tttactttgt ctttttacac ttaatatttt
       61 tttgccaatt tggaatcagg atgttttgat aactatcgtt ttcaattgat ggaagctata
      121 ttgtttgcta tcagtgaaat aattatatgg taaacagtgt tctttttctt gtttccatta
      181 taaaaatcgt atcgggattt ttcgttcttt taaattgaac atttctatct atccgcgtgt
      241 tatcaacaaa acaaaatcag gtaaatagtt gacgaaacag aaataaatac atagtattat
      301 gttttgaagc ctaagtacaa tagtctatag aaaaggagcg ataccattgg caaaacgcat
      361 tgaccgaatt tatatgtatg tcaaagaaaa aaccgctcat ttaacaaagg cagaatatga
      421 tcaaggagta acaacacagg aaattgctga agtgttaggg attcagcgaa caaatagcag
      481 taaagatctg aatcagctag tgcgcgaagg aaaactgata aagacagacg gacgaccagt
      541 acgttacata tatcaaacac tcgttacgca cgtaaagcca gttacaaaac atgtagtcag
      601 ttacaaagaa acgccggtct ctgaagaaaa aaatacactc caaatagata ctaaggatat
      661 ctttgcaaaa atcattggag ctaacggcag catgaaaaat tcagtggaac aggcaaaagc
      721 tgcgattttg tatccgccaa gaggattaaa ttgtttgatt acaggaccta ccggatcagg
      781 aaagacttat tttgcacacg cgatgtatca ttttgcaaaa gcgcatcatg taatagatga
      841 ggaaacggaa ctgattgttt tcaattgtgc tgattatgcc aataaccctg agcttttgat
      901 gagtcattta tttgggtacg caaaaggtgc ttttacaggc gcagatgaag aaaaaatggg
      961 gattatcgat caagcggatg gcggtatgct gtttttggat gagattcacc ggttgccgcc
     1021 tgaaggtcaa gaaatgatct tttactttat ggatcatgga acttacagtc gtcttgggga
     1081 aacaacgaaa tcccatgaag caaatgtacg gatcgtaggt gcgaccacag aagacccagg
     1141 ttcttctcta ttagaaactt ttgttcggcg tatcccaatc aatatcaaac ttccggcttt
     1201 tgaaaaacgt cctgcaaatg agaaagtcga tttagtaaaa atcatgattg cccacgaagc
     1261 aaaccgcacg cagcgaaaga tttctttgac agaagatgta gcaaaagcat tgatcggcag
     1321 tgtgacctat ggaaatatag gacaattgaa gtcaaatatc cagttagtat gtgcacgagg
     1381 atttctaaat catatgcaat cacccgaaat ctcgatcaca atcgatgatt tgacagaagg
     1441 gattcgtagc ggattgattc aattagcaag caaccgcagt gcaatggcag agctttctaa
     1501 aatattggag ccaaagataa ctgtagcacc aaatgatacg atcatgaaaa tccaatcgga
     1561 ctcctatgag ttaccttata atctatatga tatcatcgga gataaagcag ctttactgaa
     1621 gtcggatggt ttggatcaag aagcaatcaa tcatttcatt tctacagata tcaacatcca
     1681 tctgaagtct ttctataaag accatggttt ttcttttaat gcagacagca aattagcaga
     1741 atttgtagat ccgaaaatca tagaagtgac caatcagatt tatgtaatgg tcaaaagatc
     1801 tttaccatat gagtttcagc aaaactttat ttatgctatg agcttgcata tcagttcttt
     1861 tttgaaaaaa atcaacttag gagaagaacg gcatacgaat gataacatcc gtgagatggc
     1921 ttttgatttt ccagatgaat atgctgttgc gaaagaagtg cgtagttata tcgaaacgta
     1981 ttttcaagtg gagattccag aaagtgaaga ctattacttg accgttctac tcgtctcgtt
     2041 acgggcaaat caagcaagcg gcagaatcgg tgtagtcgtt gcagctcacg gaaacagcac
     2101 agcaagcagt atggtccaag ttgtccaaca gttgttagat gcagagaacg tacgagcagt
     2161 agacatgcct ttggatatgg atccgaaaac agcattggac cgaattgaac gcaatgtaca
     2221 agaagtagat gaaggaagcg gggtcatact cttagtagat atggggtccc ttgcgtcgtt
     2281 taattcgcaa attcaaagag acactggaat tccagtacgt actgttgata tggtaacaac
     2341 ttctctagtt ttggaaactg tacgaaaggt ctcagtatta gggacagatc tagatatgtt
     2401 gcatgaatca ttgaaaaatt ttcgaggtta cgcagaaata tcttctgtag aatctgttca
     2461 ggaagcaaaa cctattcata agaaaaaagc tgttttggct atctgcgcat ctggcgaagg
     2521 tacagcacaa agaatcaaag aattgatcga acgagcggta aacaagcgtc aagaaacaga
     2581 attagaagtt ctagctttgt cgattgtgga agtgaaagaa gaactgccag ttatccaaaa
     2641 agaatatcag atcatagcta ctactgggat tactgatttg aatatccaag ccccatttat
     2701 tcctttagaa cgttttattg atcaaaatat cgaagtcatt ttggatcagt tgctgatgga
     2761 atcagaattg gaggaaactg aattcatctc cctagatgaa gagtcagcta aaaatacgtg
     2821 tgttgagttt atctctgata acttcatctt tattaatggt agtaagttaa tcgatccaat
     2881 gtggcaattt tctacacaaa tctctcagac gacgggaatc ggcgatgaag aatatggatt
     2941 caaaatcaac ctagtgatgc acacagcagg aatgatcgaa cgtattattc ggaatgaacc
     3001 attgactgtg gaagaaaacg aattgacaaa tacaacgaat gatcctcttt atagccaatt
     3061 ggcagcctca gttgttctgt tggaagatca gataaaagta aaagtgccga tagaagaaat
     3121 gtattatctg ctacgtctag tccataatca gttagataaa aaagaataca ctgtgccatg
     3181 aatacacaaa aacgatacac ttttatagtg tatcgttttt gtgtattggt taagaatcct
     3241 ttaaattcaa ttagtgtatc gtaaaaaagt tggcacgctt tttgcttata gtagtgtgtg
     3301 ctaggaggtg gttgttcaca cagaaatgat aggggtttct gtgaagtagt gaggaagaag
     3361 gagttttgca gatggatatt cgattggcac gtatagatga tcgtttaatc cacgggcaag
     3421 tcgcaacagt ttggtcgaag caaacaggtg ttgaacgtat cattgtgatc agcgatgtag
     3481 tcgctcaaga taaattgaga aagtttctac taaaagaagc tgcaccgccg gggatcacag
     3541 caaatgtaat aaccgtgcag aaaatgattc aaatctatca tagtggatta ttatcacgag
     3601 caaaagtgat gcttttattc accaatcccc aagatgttga agcggttgtc cgctgcggtg
     3661 tacagttgaa gtcgttgaat atcggcggta tgagttttac tgaaggcaaa tcaatgatta
     3721 ccaattttgt ttcagtaaat caacaagata ttgattcctt tcgttacttg aacagtcaag
     3781 aagtggagtt agagattcga aaagtacctg ctgacaggaa aatccttttg atggaactac
     3841 tagcgaaaat caaaaaggtg tagcaagaat ggttgttgga aaaggtcaaa taattctgtt
     3901 gtaatggtta gcaattatta atatttttga atttgttaca acaaaagtaa ataggaggta
     3961 taaatatggt agggattatc ctagcaagtc atggacaatt tgctgaagga atcttacaat
     4021 ccggttcaat gatctttggc gaacaagaaa acgtcaaagc cgtgattttg aaaccaagtg
     4081 aaggtccaga tgacttgaga gccaaattgg aagaagcggt tgcttctttt gataatcaag
     4141 acgaagtgtt attcttagtt gatttatggg gcggaacacc gttcaatcaa tcaaacacat
     4201 tattcgaaga gcacaaagat aaatgggcaa tcgtcagcgg tttgaattta ccaatgttga
     4261 ttgaagccta cgcatcacgc ttttcaatgg aatctgctca tgaaattgca gcacacatca
     4321 ttgaaacagc aaaagacggt gtaaaagtaa aaccggaaga attagaaccg gcagaagcac
     4381 cgaaagcagc agttgaagac gcacaaccta aaggagcact tccagaagga actgtggtcg
     4441 gagacggaaa aatcaaatat gtattagcac gtgttgactc acgtctgtta catggacaag
     4501 ttgcgacagc ttggacaaaa gcagtgcaac caaaccgtat tatcgttgtt tcagatgcag
     4561 tatcaaagga tgatctgcgt aagagactaa tcgaacaagc tgctcctcca ggtgtaaaag
     4621 caaatgttat tcctattagc aaaatgatcg aagtagcaaa agaccctcgt tttggaaata
     4681 ccaaagcatt gcttttattt gaaaatcctg aagacgtatt gacagctgtt gaaggtggcg
     4741 tagacatcaa agaattaaat gttgggtcaa tggcgcattc ggtcggtaaa gtcgttgtaa
     4801 gtaaagtatt gtctatggga caagaagacg ttgaagcgtt tgagaagctt gaacaaaaag
     4861 gtgtgaaatt cgatgtacgt aaagtaccta atgattcacg cgataacatg gatgatattt
     4921 tgaaaaaagc aaaagctgaa ttagcaaaag cgtaataaat aatattaaaa tttataggag
     4981 gcttatcatg tctattattt caataatttt agtcgtatta gttgcctttc tagctggtat
     5041 ggaaggtatt cttgatgaat ttcaatttca tcaaccacta gtggcatgta cattgatcgg
     5101 tttagttacc ggtaacctcg aagctggtat cgtacttggc ggtacgcttc agatgatcgc
     5161 tttaggttgg gcaaatatcg gtgccgctgt agcaccagat gctgcattag catcagtagc
     5221 atcagcaatt attttagttt taggtggaca aggtgttaaa ggtgttcctt ctgcgatcgc
     5281 gattgccgtt cctttggctg ttgcagggtt gttcttaaca atgatcgtac gtacaatcgc
     5341 tgttccaatc gttcatttga tggatgcggc tgctgaagaa ggaaacatcc gtaaggttga
     5401 aatgtggcac atcattgctg tatgtttaca aggggttcgt atcgcggtcc cagcagcagc
     5461 gttgctattt atcccagcac aaactgtgca atcattcctt gaatcaatgc cagcatggtt
     5521 aacagatggt atggctatcg gtgggggaat ggtcgtagct gtaggttacg ctttggtaat
     5581 caacatgatg gctacaaaag aagtatggcc attcttcgtt attggtttcg ttgtagctgc
     5641 aatttctcaa ttaacattga ttgctctagg tgctttaggt gttgcattag ctcttattta
     5701 cttgaacctt tctaaaatgg gtggttcatc aaataatgga ggcggaagca actctggtga
     5761 ccctttaggc gacattttga atgactatta atcttgaagg aggaaaataa aatggcagaa
     5821 gaaaaaatca aattatcaaa aaaagatcgt ttagctgttg cgtggcgctc taccttcatt
     5881 caaggttcat ggaactacga acgtatgcaa aacggtggct gggcattttc tatgattcca
     5941 gcaatcaaaa aattatacaa aacaaaagaa gaacgttctg cagcattaaa acgtcacttg
     6001 gaattcttta atacacaccc atacattgct tctccaattt taggggttac attggctctg
     6061 gaagaagaac gtgcgaatgg cgcgcctgtt gatgatgtag cgattcaagg ggttaaagta
     6121 ggtatgatgg gtcctttagc tggtgttggt gacccagtgt tctggtttac agtacgtcca
     6181 atgctaggtg cactaggtgc ttcattagct atgggaggaa atatccttgg accaatcatc
     6241 ttcttcttag gttggaacat tattcgttgg gcattcatgt ggtatacaca agaatttggc
     6301 tacaaagctg gttctaaaat tactgatgac ctttctggcg gattgttaca agacgtaaca
     6361 aaaggtgctt caattttagg gatgttcgta ttagctgccc ttgtacaaag atgggtatca
     6421 atcaaattct taccagttgt atcaactgta aaattagata aaggtgctta catcgaatgg
     6481 gataaattgc cttcaggtgg tgaaggaatc aagagtgcat ttgaacaagt taataatggc
     6541 ttagcccttt ctcctgaaaa ggtaacaaca ttacaagaca acttagacca attgattcct
     6601 ggtttagctg cattaggatt aacattgtta tgtatgtggt tgcttaagaa aaaggtttct
     6661 ccaatcgtta tcatccttgg tttattcgta gtcggtgttg ttggacacgt catcggactt
     6721 ttataatcca taaaaatata gctcgggcgt tgtcccgagc tttttttata tagtatactg
     6781 ttcataaaca aatatctgga gggagaaaat ggttcaatca atcaatacaa aagtagactt
     6841 ggtaattgat gctacttcgt ttacgggtct gacagattac gggcaaatca tgataggtga
     6901 taatggtttt gagttttacc atgcgcgaga tagacgcaaa tatatccaaa ttccatggga
     6961 agaagtggat tatgtactag catcagtcat gctaaaggga aaatggattc ctcgatatgc
     7021 cattcaaacg aaaaaaaatg gtacatacac attttcttcc aaagaaccta aaaaagtgct
     7081 tcgtgcgatc agagaatatg tagatgaaga tagaatggta caatcattga gtttctttga
     7141 tgtagtgaaa cgtggtattc gtagtatgtt taaacgcaag taaaaaataa agaaaacttc
     7201 taagaggagg ttttctttat ttttttactt tgcagaagaa aatatgaaat agcaaaacca
     7261 attatttgtc ccctttaaat cccatatgct aaaattgatt agcaaagaag gaggttatat
     7321 tatgagttgg ttatggacat tgattgttgg agccgtgatc ggagcaattg caggtgcgat
     7381 caccagtaaa ggaaattcga tgggctgtgt aacgaatatc attgctggac tagtcggttc
     7441 aagtattgga caagcgattt tcggcgaatg gggaccaaaa gctgcaggta tggcacttat
     7501 tccatctatt ttaggcgcag tgattttggt agcagttgtc tcatttttct ttggaaaacg
     7561 atcataagtt tttacaaaat agtaaactaa aaggagttgc agcgagactg tgactccttt
     7621 ttggctttat ttatttaaaa taaaaagaag ttttccggaa atttttattt aactgtcgtg
     7681 tacgaagaaa agtttgctat aatggaaaaa agcgtgcaaa gaaagaggga gtttcattat
     7741 gatgctacgt gtagaaaaat tgcgcaaaaa aatgcaagaa gaaaatttgg attcattttt
     7801 ggttaccagt ccgtacaatc ttcgttactt aacgaacttt acaggtacga caggattagc
     7861 tgttattact ttggaaaaag cattttttat tactgatttt cgttataccg agcaggcggc
     7921 agcgcaggct caagggtttg aaattattaa aaatgtcgga cctatttttg atgaggtagc
     7981 aaacttagta cgcaaagaag aactgcactc attagctttt gaggaaacaa cagtctcatt
     8041 tttagaatat tcggttttag aagaaatcat cgatgcggaa ttagtacctg tttcacagat
     8101 gatcgaagaa ctcagagaag tgaaagatga agaagaaatc gctattatcg aaaaagcatg
     8161 tcatattgcg gatatggcat atgatcacat cctgaaaatg atccaaccgg gcatgactga
     8221 gattgaagtc gcaaatcaac tagactttta tatgcgttct cttggcgctt caggtgtttc
     8281 ttttgatacg atcgttgcta gcggattgcg ttcggctatg ccgcatggtg tagcaagcaa
     8341 aaaaatcatc gaacaaggtg acttgatcac attggacttt ggttgctatt acgaagggta
     8401 cgtttccgat atgacacgta cattcgctat tggtgatcct ggggaaaaat taaaagaaat
     8461 ttatcaaata gtcttagatg ctcaattagc agttattgat gctgcaaaac caggaatgac
     8521 tggtgtccaa ttagatgcag ttgctagaga ttatatttca aaacatggtt acggggaagc
     8581 atttggacat tctacaggac atgggatcgg tttagagatc cacgaaggac caaacgtttc
     8641 ttctcgtgca gaaaagcaat ttgtaccagg aaatgtgatc actgatgaac cagggatcta
     8701 cttaccagga atcggtggag tacgtattga ggatgacttg ttgatcacag aagatggaaa
     8761 tcgtgtgttg actcgttcac caaaagaatt gatcatctta tagtttcatc aatagaagaa
     8821 gtaagcgtaa aaatcagtgt tcacagactt tgttatagaa aatcactcga tttaatgata
     8881 cactatagaa gaacttttaa gctgtaagag ataataaagt tgggtgtttt ctccaattca
     8941 tagcagtttg cagctgatcg gcggcagttt tcttaccacg tgatcactat gccgcatcat
     9001 agagaattcg gatgtatctc gtgcttaggc aaagggagga ataaataaat ggcagatgaa
     9061 aaaaatttga ttttaaacgc aaaccaagat ttaggagaga tcgtgatcgc tcctgaagtc
     9121 atcgaagtaa ttatcgggat tgcagcttct aaagtagaag gcgtatacgg aatgcgcgga
     9181 acttttgcca gcaatgtcac tgaattatta ggacgtgcag ctcacggaaa aggtgtttac
     9241 ttagcaaacg aggaagatgg cttgaaagta gatctttact gttatctaga atatggtgtt
     9301 tcagttccta aagtagcaat ggaaatgcag gaacgggtca gccagcaagt ccttttcatg
     9361 acggatatcg atttatctga agtcaatatc catgtagtag ctgttgttcc tgaaaaatta
     9421 gaacaaccaa caatcgaaga actttttgaa gacgaagagg aagagaatga ataaagaatt
     9481 atcaagacac gagattcggg aaatggcatt gcaggcttta tttccattag acttcaatgc
     9541 agacctaaca aaagaagatg cgattttcaa cgcaatcgaa ttagaccacc gcgacatgat
     9601 caacgaagat gaatcagagt ttgttcctgt ttatcttgat acgctagttg gcggtgtctg
     9661 tgcaaaaaaa gatgaattgg ataaagtgat tgaaaaacat ttaaaaaaca attggcacat
     9721 caatcggatc tcaaaaatgg atttggtgat cttgcgtatc gcgatttttg aaatgactta
     9781 tgtgacagat gtaccagcgg ctgttgcttt aaatgaagca atcgagttgg caaaaacatt
     9841 tagtgatgac cgttcacgta aattcgtcaa cggtgtttta tccaatgtat tgaaagaatt
     9901 agaagctggg gcgtaagtcc tagctttttt ctatgaatca tcataaacct gttataaatc
     9961 gggaaaattc tatggtagaa tgaaaacaca aaaaatatct gggagtggtt agatggcaga
    10021 attgattaac ggaaaagaat tagctgaaaa aatgcaggca gagattgctg aaaaaatcca
    10081 aaaattgaaa gataatggta tccatcccgg attagtcgtt ttattggtag gggaaaatcc
    10141 agccagccaa atctatgtaa gaaataaaga acgtgtagca aaagaaatcg gaatccattc
    10201 attggtagag cgttatcctg agacgatttc tgaagacgaa ctacttgcag aaattgaaaa
    10261 atacaatcaa gatcctagtt ttcatggtat attggtccaa ttaccattgc caaagcatat
    10321 agatgaagaa aagatcctgt tagctatccg ccctgaaaaa gacgtagacg gttttcatcc
    10381 gatgaattta ggcagactcc ttgcgggtaa accggacaag attccttgta ctccatacgg
    10441 catcatgaaa atgtttgaag cttattctat cgatccggcg ggtaaacgag cagtagttat
    10501 cggacgaagc aatatcgtcg gtaaaccgat ggctcagcta ctcttgatgg cagatgcaac
    10561 tgttactgtt gctcattcta aaaccgaaaa tctggctgaa ctggcacaag aagcagatat
    10621 tttagtcgta gcaataggac gtggacattt tgtcacaaaa gaattcgtaa aaccaggtgc
    10681 tgtagtgata gatgtaggga tgaatcgtga tgctaacggt aagctgatcg gtgatgtgaa
    10741 atttgatgaa gtggagccta ttgcaggctg gatcactcct gtgccaaagg gtgtagggcc
    10801 aatgactatc acgatgctga tgtatcaaac cgtaaaatct gccgaagctt ttggagcagg
    10861 tgaatagatg gcacaagaat atttaactgt cactacatta acgaagtatt tgaaaagaaa
    10921 atttgatgcc gatccttatt tagaacgcgt atatttaaca ggcgaaatat cgaatttccg
    10981 tttacgtgcc aatgcccatc aatatttcag cttaaaagat gaccatgcaa aaatatctgc
    11041 tattatgttc aaaggagcat tccaaaaatt acgattccag ccaaaagaag gaatgaaagt
    11101 ccttgtcgtt gggcgtattt cattatatga agcgggaggt tcttatcaaa tctatgtaga
    11161 gcacatggag cctgatggaa taggtgcttt atatcaagaa ttggaagaac gaaaagaaaa
    11221 gctgatgaag gaaggccttt ttcaagggcc taaaaaaatg ctgccacgtt tcccaaagcg
    11281 aatcgcggtc cttaccagtc caagcggagc ggttatccgc gatatcatca cgacggtgaa
    11341 aagaagatat ccaattgtcc aattggtttt gttcccaaca gttgtacaag gaaaccaagc
    11401 agcggacaat gttgtcagga atatccagag agtagaagag atgggcaatt tcgatacaat
    11461 gatcatcggt cgtgggggtg gttcgattga ggatttatgg ccgtttaatg aagagcgggt
    11521 tgctcgggcg atttatcaag ctaatacgcc ggtgatttca tctgtaggac atgaaacaga
    11581 taccacgatc gctgatttag tagcagatgt tcgggctgcc actccaacag cagctgcaga
    11641 attagctgtt cctgttttgt cagaagagtt gatgcgcatt caagaacggc aagctagatt
    11701 gcagcaggcg tttgtacgcc agatccagcg caaacaagaa cggttcgagc gtgctcgacg
    11761 ttcctatgta tttcggcagc ctgaaagatt gtatgaaggt cagaccatca aattagacca
    11821 gttgaaacag cgattatatc aagctacaca gcaaatttat catgcgaaag aaaaacaaac
    11881 gatcgcatta agccaccaat tggaacaagt ggctccgctt tatcgagtta aagcagctcg
    11941 ccaagaaact gcttatctag aaaaacgctt agaagagaaa atccaacaat atatgaaaca
    12001 acagcagcag cgttttgctc aagctgttca atctcttgat ttgttgagtc cattgaaaat
    12061 catgggaaga ggctacagct atacgacgtt aaatgatcaa gtagtaaaaa gtgtcaccga
    12121 gattcatcaa ggggatttgc tgacgatcca ttatcaagat ggaatcgtta aaggacaagt
    12181 acaagagata gacaaaggag aataaaaata tggaaaatcc aacttttgaa gagtcactgc
    12241 aagaattaga aaaaattgtc atgcagttag aacaaggaga cgttccatta gaatcagctc
    12301 tagattcgtt taaacgagga atggaattaa gcaaacattg ccaagataca ttagctaaag
    12361 cagaagagac cttgacgaaa atgatgacag aatcaaatga agaagttgat tttgacggaa
    12421 acgaggaaag ctgagatgag attaactgac ttttcagcta ttcatctacc tgctgtagaa
    12481 aaagaaatct tgtctttttt agatgagcat acaacggata gaggactcta tgatgcgatg
    12541 agttattcag tgaaagcagg cgggaaaaga atacgtccct tattactttt aacggccgtt
    12601 gcttcctttg atgagcctat tgatgttccc gtctatcaag tagcagctgc tttagaaatg
    12661 gtgcatacgt attccttgat ccacgatgat ttgcctgcga tggacaatga tgatcttcgt
    12721 agaggaaaac ctaccaatca taaagtattc ggcgaagcat tagctatatt ggccggagat
    12781 ggtttgctta caggagcatt ccagctaatc agtatggcac acttaggtaa ttctcctaag
    12841 cttctgctgc ttcagcaatt agctgtttgt gcgggatcac aaggtatggt tgctgggcaa
    12901 gctgcagata tcgagggcga atcgaaaaag ctttctttag aagaattagc atttattcat
    12961 gaaagaaaga cagggcattt gattcgttat gccttgctgg ctggtggcat attagcgaag
    13021 caacctgaag aaatcttatt gctacttcaa cgattagccg aacatttagg tttagctttt
    13081 cagataagag atgatctact cgatgtgatt ggtacaacga aaacattagg gaaaacagct
    13141 ggtaaagatg aacgtatgga aaaaaatact tacccgcgtt tattaggcct agaaaagaca
    13201 cgtgaggcgt tggagattga gctgttatcc gccaacaaga tcatagacaa attagaagag
    13261 gacgtttttt cttttgatgg cgggctgatg cgccagatga tcaagcaatt tgatgtggag
    13321 aaatgaggga aagaatggaa aaagaacgcg tagatgtatt agcggtcaaa caaggattat
    13381 ttgaaacaag agaacaagcc aaacgttcag tgatggctgg tttgatttac aacgaaaaaa
    13441 acgagcggtt tgataaaccg ggagaaaaaa ttccagtgag tagtgaatta agagtcaaag
    13501 gtaaaaaact tccttatgtt tctcgagggg gattaaaatt agaaaaagca ctcaaagcat
    13561 ttgatctatc tgttgaagga aaaacattgt tagatattgg tgcatccact ggcggattta
    13621 ctgatgcagc tttgcaaaat ggcgcaaaaa tgagttatgc tttagacgtt ggctacaatc
    13681 agctagcttg gaaaataaga caagatccta gagtcgtcgt aatggaaaga gtgaattttc
    13741 gttatgcaaa acccgaagac tttaccttag gaattccaga agttgctgtt atcgatgttt
    13801 cttttatttc actaaaactg atgctgcctc cattacatgc tattttaaaa gaagagggag
    13861 aagtgattgc tttaatcaaa ccccaattcg aagcaggcag agaagctgta gggaaaaacg
    13921 gaattgttcg tgaccctcag acccatcaaa aagttttaga agacattttg tcatttgcgg
    13981 cacaaggtgg atatgatgtg ctggaattaa gttattctcc gatcacgggg ggagaaggaa
    14041 atatcgagtt cttggctcac ttgaggaaag tacccgaaag cggaacaatc aattcagcta
    14101 ttaatatggc agaagtggtt tcaaatgcac acgaacagtt tgaccataaa taaattgtaa
    14161 ctgtgaaaat caagtgagaa gtatgcggat tcttctttat tataccaagg aaataagcta
    14221 tcattgatta agaagaatat gctaaggagc gaagacgtaa tgagaaaaaa agatcggcat
    14281 cgtttgatta ctcgattgtt gagtgagcaa gatatccgaa agcaggaaga atttgttgaa
    14341 atcctgaaaa gcaaaggaat atctgttact caagctacga tttccagaga tataaaggaa
    14401 ctgaaactga tcaaggtacc ggcttcagat ggcggctacc gttatagcat accagctgaa
    14461 acaaacgaag atgtaaatac taaattggaa aaactattaa aagacgcttt cgtggcagtt
    14521 gaccaaatgg aaaaatttgt tattttgaaa acattgccgg gaaatgcttc ggcagcagca
    14581 aatttgattg ataaacgtta caagaaagaa ttattttcga ttatcaatga tgacgataat
    14641 gttttgatga ttacacgaac tgaagaccag gcagttttat tgaagaaaga cttcctgcat
    14701 tacctttaag ttgaggagcg aatgtgatgc tacaagaaat cagtattact aactttgcga
    14761 ttattccgga attgcggctt tcttttcacg aaggaatgac cgcgctgacc ggagagactg
    14821 gtgcgggtaa atccattatt atcgatgctt taggtctgtt agcaggagga agaggttcaa
    14881 gcgattatat acgtcaagga gcagaaaaat gtgtgcttga agggttgttt gaactaccaa
    14941 aacaagaagg attctctgaa ctgatggttg aattagggat cgaaacagat gaggacaatc
    15001 tgattgttcg acgggatatg tccttaactg gaaaaaatgt ttgtcgagtg aatggtcata
    15061 ttatcacatt agctaatctg agaagaatcg gcagttattt agtagatatc caaggacaaa
    15121 acgaacatca ggaactgctc cagcctgaat cacatcttgc tttattggat cgttttggag
    15181 atgtagcttt ccaacagaag aaaaagagtt atcagcaaga atatatctct tatcgtgagc
    15241 tggaaaaaag ggtacgaaaa gtgcagcaaa atgaaaaatc ctatgttcag agaatagata
    15301 tgctccattt ccagcaagaa gaaatagctg ctgctgattt gcaagtcgga gaagaagaga
    15361 aattaaaaga agaaagagaa aaacttagca attatcaaaa aattgctgat ggattagctg
    15421 caggttacgg agcactgacg aataatgaac aaaacagtgt agatggtgtt ggcttggccg
    15481 tttcagaact gcaagggatc gcccatctag atgtggagta tgaagcaatt tatgaaaata
    15541 tccaaagtgc ttactatttg ctgcaagatg caatcggcga tatgagtcgt cagattgatt
    15601 tattggagtt agatgagagt cgtttagaag aagttacgca acgtttagaa ttaatccgac
    15661 agttgaaacg taaatacggc gaatccattg agtcaatatt ggcttactat gacgaaatca
    15721 ccgaagagct agcttcttct gatttttcag aaggtcaatt ggacaaaatg aaagaggaac
    15781 tagagcaaaa agagcttcta cttcagcaac aagccgcaga tcttcatgaa gcgcgtaaaa
    15841 aaatcgcaaa agaattggaa aaatccattc tgcatgaatt gaaaagtctg tatatggaaa
    15901 acactgagtt tgaggtacgt ttcttaaaag aagaaaatag acaattgaat catgatggat
    15961 ttgaccaaat cgaattttac attacgacca atccaggaga gccactgaag cctttggtga
    16021 aagtcgcttc tggtggcgaa ctgtctcgga tgttgcttgc tttgaaaact attttttctt
    16081 ctgagcaagg tgtgacaagt attatttttg atgaagtgga tacaggtgtg agcggaagag
    16141 ttgcacaggc catcgcagat aaaatttctc aaatatcgaa atactctcaa gttttgtgca
    16201 tcactcatct gcctcaagtt gctgcagtcg ccgactatca atattatatt gtgaaagcag
    16261 tgattgatgg acgtacgcaa acttctgttt cagagttgaa aacaaaagaa agagaagaag
    16321 aaattgcacg tatgctggct ggaagtgaga ttacaaaact cacactcgaa catgcaaaag
    16381 aactattgaa actcgcaaaa aggacctgag ccacctcgca gtggttcagg tccttttcag
    16441 cagctgatag ctatatttta tttttacatg acactcatta cagcagtcaa tacaacagat
    16501 ccaatcgtta aaatcagcat tgtccaaatg acaaattttg ttactttagc aaaagtactt
    16561 gtttgttttt tttcacgcat tgttttcaac ctcgtcatta attagttgat tcaagtgtac
    16621 aatctttttt ccatttccac aagagggctt ttttataaaa acttcccttt ttttaaataa
    16681 taggtagtta cgatacaaat aaataatgtt aatagaacta gccatataaa ggcatcatcc
    16741 ctttcagcaa taggtaactt aatgttcatt ccatagatac tgccgacgat tgtcggtata
    16801 gttaaaataa tcgttaaaga agttaaaatt ttcataatat tattcagatt attcgatacg
    16861 attgctgaaa aagtctgatt catttgttct actagtttta attgaatgcg agaagtagtc
    16921 attgcctgct ctgtttccac caatacatca cgtaaatgat ttttcaaagc atgattttct
    16981 tggaaaagtt tattttgcgc tagttctttc aatgcatcta aattagcaga agtcgcttct
    17041 ctgaaataaa cgaggctttt ttggatatcc atgatttgat aaagttgttt gttttcagtg
    17101 gatacttgaa gtttggcttc caaagtatcg cattgagatt gaagcgtagc taaataactg
    17161 ttgtaagaga gtgtgacctg ccaaatgaat tgaaagaaga tattgagatt aggcgaaata
    17221 tcactttttg gaaaggtctg gctaaagact ttctttaaaa acagtggttc atgattcgta
    17281 attgtgataa gcttcttttt gggcgtcaaa ataatagaga gcgggtatgt atccacttga
    17341 aaataaccgc taggacttgt tttagcaaaa ggatattgta acaataataa cgctggcttt
    17401 gtcaactttg attgattgaa ttcttctgta cgggaatttt ctgcatcgtc caatatggaa
    17461 gtgatgtaat ctgacggaat ttcaaattga tgtgtcagct gatgaatctc ttcttgatta
    17521 ggacgttcta cacaatacca gatcgtttgg tcagtttcct ttccggtatt acgcagtttc
    17581 tcattatcta atgtaaaata tttgatcatg attttcctcc tgttgcctgt ttcttttatt
    17641 ataacggata gggaattgga atacatggaa tgtgtttgta agatatagaa tataactgca
    17701 taaatttaaa taaaatgaaa cagttgtgta aagtatatac agtatacttg aagcaacgat
    17761 aaaaaaggag tttacgttca tgggcacatt cacaccactt atcttgtttt ggtatattta
    17821 cccggtaatc gttttgtttg gttgccaatt tcttgtaaaa ttattttcgt taaatcgtcg
    17881 ttttaaaata aaagcccctg atttggcgat tccttttttg tggggcggta tgcatgcatt
    17941 gtctagaaat acagggacaa tttctatctt accgtttttc tttatttctg ttttgctaat
    18001 gggaatttgt attgctgttt tccaagcata ttattatgaa gaaattattt atccgcgtta
    18061 tttcaagatg acttggcgtt tggtttttct gttgacaatc gtcttgtacg ctgtcttgat
    18121 cattgtgaac atactttctt acctatgaaa aaaatagaaa agctgtaaaa agtcttttaa
    18181 aaggcttttt gcagcttgat ttttaaaaaa atgtttatga ataaaaaaag ttgttcccgg
    18241 atttcccaga aaaggtggta gaaagtgggg gattgtggta gactaatttt agttagtgga
    18301 ggaatggggg ggctttcaat gttgatgggt gaattccaac ataatattga tgcaaaagga
    18361 cgtttaatcg tgccctcaaa acttcgtgaa gaacttggcg aaaagtttgt tctgacacgc
    18421 ggattggatg gctgtctttt cggctatccg atgagcgaat gggaaaatct ggaagctaaa
    18481 ctgaacgaaa tgccgttggc taaaaaagac gcacgtactt ttgtgcgatt cttctattcg
    18541 gctgccactg aatgcgaact tgataaacaa ggacgaatca atatacccag cacgttaaga
    18601 aattatgcag ctttgacaaa aggttgcgta gtcatcggtg tatctaaccg aattgaaatt
    18661 tgggatgaga cacgatggca agatttttct gcagcagcag aagagaactt tgacgaaatt
    18721 gctgaaagta tgattgattt cggactataa gaataggaag aggctgacta atgactgaaa
    18781 catttcaaca ctatacagtc atgttgaaag aaacggtaga tggattgaac atcaaaccgg
    18841 atggcgttta tgtagactgt acactcggcg gtgccggaca tagtgaatat ttattaagcc
    18901 aactaagttc taaagggcat ctgtatgcgt ttgaccaaga tcaaaaagca atcgatcacg
    18961 ccaagctgcg tttagcttct tatgtcgaac aaggtatggt cacatttatc aaagcgaact
    19021 tcagagaatt agaagaacgc ttgagtgagc atgtagataa ggtagacggc attttgtatg
    19081 atctaggggt ttcctctcct cagctagatg aagcagaacg tggatttagt tatcatcaag
    19141 atgcaccgtt ggatatgcgc atggatcagt cagctccttt atccgcttat cacgtaatta
    19201 atgaatattc ctaccatgaa ttagtaaaga ttttcttccg ctatggcgag gagaaatttt
    19261 ccaaacaaat tgctcgtgaa atcgaacgag tacgaaaaac aaaaccaatc caaacaactg
    19321 gtgagcttgt cgaaatcatt aaacaagtca tcccagctcc cgcaagaaga aaaggcgggc
    19381 atcctgcaaa aagaattttt caagctgtgc ggattgcagt aaatgacgaa ctcggtgccg
    19441 aagaggcctc tttagaacag gcaatccggt tattgaaagt caatggaaga atcagcgtaa
    19501 tcacattcca ttcattggaa gacagaattg tcaaaagtat gtttaaagaa tatagtacgg
    19561 tacaagatct accaccggga cttcctgtca tacctgacga attccaacca gaactgaaag
    19621 tcattactcg taaaccaatc cttccttcag aggaagagct aacagaaaac aatcgatcac
    19681 gcagtgcaaa gttacgtatt gcagaaaaaa taagaatgaa agaggagtag aatgatggca
    19741 gaattaaaga aaatgcaaga ttacgaatat gatttacctg aattggtgga tcagccggaa
    19801 caacaaatgc ctgattcttc ttcgaatcaa gaaatcattc ttccacaatc accggcaaaa
    19861 cgattaaagc agatttctgc tttggaaaaa attgctgtgg caagcgtggc gattgctatt
    19921 gttgctttat gtgttttaac agttatgctg cgcacaaata tcagcggagc tgaaaaagaa
    19981 atcacgtcaa tacaaacaga aatcaatgat aaaaagcaag aaaaaacgag tttagaacaa
    20041 gaaaaaaacg aactttctcg tactgaacgg attaaacaaa tcgcagaaga aaaaggattg
    20101 tctattaatg acgacaattt aaggaaagtg aagtaaatga gtcttaaaaa taaaattcgg
    20161 cggtttatgg aaaagaaaaa tctaaatccg ataaacaatc gcaaaaaagt aggtatcatt
    20221 ttatttgcta cgagtattgg attgttcttt ttatttgccg tccgtttctc gtatatcgtt
    20281 attggaggtc atgttgctgg tacctcatta gctgaaaaaa caaaacagtt gtaccaagga
    20341 agtgaagtag taaaagcaaa aagaggaacg atttatgatc gtaacggtgt ggcgctcgca
    20401 gaagatgcct cctcttattc aattaaagcg atactctcaa aaacatatac ctctggggat
    20461 aaaaaactgt atgttgaaga aaagaatttt gataaaatag cagaaatcct gcataagaat
    20521 ctttctatag acaaaaaaga tgcactgaat attttagagg acggcgcaaa aaaagagctg
    20581 tatcaagttg aatttggtag ctatgggaaa aatatctccc aagaaaccaa gcaaaacatc
    20641 gaagcggaca tgaaaaaaga aggtgtcgct ggtctttatt ttgtcgacca tcaggctcgg
    20701 atgtatccaa atggcgtctt ttcttctcat tttattggat acgcagttcc agacaaagat
    20761 gagaatggct tagttggtaa actaggtttg gagtctgctt acaatgatat cttgagcggt
    20821 aaagatggta agattattta tcaaaaagat aattttcaaa atcctctgcc aggtacagtg
    20881 gcagaagaag aaaaagctgt cgacggacaa gatatctaca cgactttaga cagcagacta
    20941 caaagttatt tagaaacact gatggatcaa gtaaatgaag aatatcagcc agaagaattg
    21001 acagcagtcc tgatgaaagc aaaaaccgga gaaatcttgg caatgggaca acgacctact
    21061 ttcaatcctg aaacaatgga aggattgact ggaaaagatg ctatctggcg taatttcttg
    21121 gtacaagata gttatgaacc aggatcaacc atgaaagttt tcactactgc agctgctatc
    21181 gaagaaggag aattcaacga gaatgaaacc ttccaatctg gaaaaatcca agtagaagat
    21241 gctacgatca atgaccatga ctttggtgaa aaaggtgtgc tgaccatgcg tcaagctctt
    21301 tcatggtcaa gtaacgtcgg gatggtcata ctggaacagc gattaggcgg acgatggtat
    21361 aactatttac aaaaactggg atttggacaa agtactcatt ctggattaga tgatgaagta
    21421 aacggtgctt tacctacatt aaatattgtc gaccgagcaa tgagtgctta tggacaagcg
    21481 gtaggtgtga cgaatttcca aatgatgaaa gctttcactt ctattgcgaa taacggtaca
    21541 atgattcaac ctcgatatat cagcaaagtg gtggatcccc aaactggaga agagcgaaca
    21601 actcaaacag aagttctagg gcaacctttt tcaaaagaaa caacagaaaa agtccgtgaa
    21661 tatatgagag atgttgtcga aagcgaaaac tacggtagtg cttatggtgt atatagtgta
    21721 cctggataca atgtatcggc aaaaaccgga atagcccaaa tcgcttctga tacaggggga
    21781 tatcaaacag gagatacagc ctacctgtat tcgattgtgg agatggttcc ttctgaagat
    21841 ccagactatg tcttgtatct aacaatgaaa caccctaaga catatgatcg aatggcattg
    21901 gctaaaatcg caaatccatt gatgaaacgg gcaatggatt ttaaagaaac tgaagaagat
    21961 tcagatacag aaacaaaaac agaaaaagta tccgtagccg attatcgtaa tcttgaagcg
    22021 gacgttgcag cagctgatgc tcaaaaaagt ggactgcaac ctgtagtgat cggtaatggt
    22081 aaaaaagtac aaaaacaatc tactgccaac ggtgatcagt tgatctctgg agaaaaactg
    22141 atcctatata ctggtggtga taagctgatg cctgacgtaa caggatggtc aaaagcagat
    22201 atcatgaagc tggggaaaat cctcggtatt gaagttagtt ttgatggaga tggttattgt
    22261 gtcaaacaag aacttgctcc atatgaaaaa atcactgaag acaaacttag ttttacttta
    22321 gaagaataag aagagaaata ggagagaaaa gagcatggaa tggacacaag cattgattcc
    22381 cattgtcagc agttgtgcaa tgacaattgc cgcaatgccg ctatttattg gttattttca
    22441 aatgaaaaag caaggtcagg cgattcgtga ggagggacca aagtggcaca atagcaaagc
    22501 cggaactcct acaatgggcg gcttagtgtt tctgatcggc tctattttga caggaatttg
    22561 ggttggagct tggcaaaaac agctaactcc tactcttttc atcttgcttt ttgtattagc
    22621 gttatacgga gtaatcggct ttcttgatga ttttataaaa atattcaaga aaagaaacat
    22681 gggactgaac tcgaagcaga aattgattgg acagattcta gggggaatca tcttttatct
    22741 tgtttaccgt tctgaaggtt atccaggtgt attgaatttc ttcggactag atctaccttt
    22801 aggaatcatt tatggtattt tcgctctctt ctggcttgtt ggattttcaa atgcagtaaa
    22861 tctgacagat ggcatcgatg gattagttgc tggcttagga agtatctctt ttgcagctta
    22921 cggtctaatt gcttggcatc agcatcagta tgatgtatta atcatttgct taagtgtttt
    22981 aggaggttta ctgggtttct tcgtctacaa cagaaaacct gccaagattt ttatgggaga
    23041 tgtcggttca ttagcgttgg gcggactttt agcggcaatt tctataatgc taaaccaaga
    23101 atggacattg cttttgattg gtttgatcta tgttatggaa acagcaagtg tgatgcttca
    23161 agttacttcc tttaagctta caggaaaacg aatttttaaa atgtctccaa ttcatcatca
    23221 ctttgaaatg tgcggatggt cggagtggaa gattgataca gttttttggt tgatcagcat
    23281 tgtgacttcg ttgatcacat tatggatcgt ttggtaggag atgacgggaa atgaaaaaaa
    23341 tatcaacata tgaaaataag aaagtgcttg tcttaggact cgcaaaaagc ggagtaagtg
    23401 cggccaaatt attacatgaa ttgggcgcac ttgtcaccgt taatgatgga aaaccttttg
    23461 acgaaaatcc ggaagcacaa gagctgcttt ctttagggat aaaagtaata acaggtagtc
    23521 atccaatcga attgttggat gaagaatttt cattgatggt caaaaatcca gggattccct
    23581 acagtcatcc tttagtagca aaagcccaag aaatgggtat tccggtaatt acggaagttg
    23641 agctagctta cgaagtagcg gaatgcccaa ttattgggat tacaggaacg aacggaaaaa
    23701 caacgacaac aacgatgaca ggactactac tgaatgcagg agcagatcaa ggaattgcac
    23761 gtttagcggg taatattggg tatccagcaa gtggtgtagc gcaagaagca aaatcagaag
    23821 ataaaattgt gatggaattg tctagcttcc aactcatggg aatcacagat ttccgccctc
    23881 atatagcggt gattaccaat atctatgaag cacatattga ttatcatggt acaagaaaag
    23941 aatatgtcaa agctaaatgg aaccttcaaa aaaacatgac agaaaaagat tatctgatcc
    24001 ttaactggaa tcagtcagaa ctacaagaat tagcgcaaag aacaaaagca cgcgtactgc
    24061 ctttctcgac aaaagaagtg ttggaagacg gtgtgtatgc tgacgattac tcaatatact
    24121 ataaaaaaga aaaaataatg gaaatatctg aacttggcgt accaggtaag cataatgtag
    24181 aaaatgcact agctgctatt tctgtagcaa aattgtatgg tatatcaaat gaagctatac
    24241 gagaaacgtt gcattttttc catggcgtac cacatcgtac gcaatatgta ggagaaatcc
    24301 aaggcagaaa attttataat gattcaaaag caaccaatat tttagcgact aaaatggctc
    24361 taagtggatt tgaaacgtct aaggtcgtgt tattggctgg cggattagac agaggaaata
    24421 catttgatga attaattcct tcattaaaag gaatcaaagc aatggtcgta tttggccaaa
    24481 caaaagaaaa gttgatggat gctggaaaaa aagcaggcat cgagacaata gtaacagccg
    24541 attctgtaga acaagcagtt cctttagcat tagaaaacag tacagatggt gatgtagttt
    24601 tattatcacc agcgaatgcc agctgggatc aatacccaaa ttttgaaact agaggaaaca
    24661 gattcatgga agctgtgaac cgattaaaat agaaaaagta gaagcgagcg ataaaaaatg
    24721 aaaattttgg ttacaggcgg aggaacaggg ggacatattt atccagctct tgcctttgtc
    24781 aattatgtaa agactcaaga accgaatgct gaattcatgt atgtgggagc aaaacgaggt
    24841 ctagaaaaca aaatcgtccc tgatacagga atgcctttcc ataccttgga gattcaagga
    24901 tttaaacgaa aaatttccat gcataacatc aagacggtcc gattgtttct taagagtatc
    24961 cgtcaagcaa aaaaaatcct cagtgatttt caaccagata tcgttatcgg tactggagga
    25021 tatgtttccg gagcggtagt gtacgctgca gccaaaatgg gtattccaac agttatccat
    25081 gaacaaaaca gtgtaccagg tgttaccaat aaatttttaa gccgatatgt ggatcggatc
    25141 gctctttcat ttaaagatgc ggcttccttt tttcctgaaa acaaagcagt tcttgtaggt
    25201 aatcctcgag cacaagaagt agcagatact aaaaaatcag atattttgaa aacatttgat
    25261 ttggatccag aaaagaaaac agtcttgatt tttggcggta gtcaaggagc acttaaaatc
    25321 aatcaagcag tatcagtttt tttaagtgaa tatattcctt cttcttacca agttttgtat
    25381 gcttcaggag atagatatta tgaagagatc ctaaataaaa taaatcctga aatacaaaat
    25441 attagtgtcc agccttatat caaaaatatg gcagaggtca tggcttccag tgatctgctg
    25501 gtggggcgtg ctggtgcaac ttcgatcgca gaattcacag ctctggggtt accggcagtg
    25561 ttggttccca gcccatatgt tacgaatgat catcagacta aaaatgcaat gagtcttgtt
    25621 cacgcaggag cagcaaaaat gattgcagat aatgaactaa caggtgaatc actaagtcag
    25681 acagtcaacg aaatcatggg tgatgaagaa ttgcaaaagc aaatgtgccg agcttctaaa
    25741 gaacaaggaa tccctgatgc ttcaaaacgt ctttatgact tagtaaaaca aataatcaaa
    25801 aaataaaggc ggtggtctta gtgagtaaga aaaaagaacc aaaaaaattg tctcatccgt
    25861 cttctgatga aaacaatttg actccttggc aaaaggctaa ccgaaaatat ctggcagaac
    25921 aagagatgaa aaaccaagag ccaaaaaaag aagacataac attagataca cccctttcag
    25981 attctgaaga agaaaaaacg gttcaagagg aacagcaaga agaaagccag tccgagaaaa
    26041 aaatcgaatt ttttgaagag atcaagcaaa agaaaaacgg tggaccatat aacggttctt
    26101 ttttgaaccg gctgcccaat ttaaaaagtc aacggcacaa agtactattt cgtcggttag
    26161 ctttgatcat cactgtattg ggtataccgc tgattttttt gatctattat gtttctcctt
    26221 atagcaaatt acaagcagtt gcagtatcag gcaataagac agtcaacagc caagaaatca
    26281 tctctgatac aaaattgtca ttaggagaaa atgtttgggg acagtatttt catcgatcta
    26341 cttatatcga tcgccttaaa aaagcacagc caagaatcga aacagcaaat atacatttca
    26401 aagggatgaa tgaattcgat ttggatgtaa cagaatataa agagattgct ttgatcgcaa
    26461 aaaacaatca atactaccca gtgattgaaa atggaacagt attagatgaa aaagtagcaa
    26521 atcctacaaa aaatctccct atcttggaag agttcaaaga ctctgcaaaa atcaaagaat
    26581 taacaaagca atacaatcag ttatcatcag aattacaaaa agcaatttct gaaatcaagt
    26641 acacgccaag agcaagcaat aaaaatctga tccaattgaa tatgaatgac ggcaatcaag
    26701 ttattgtaaa tatcaataat cttgcgaacc aaatgaaata ttattcgcaa gtagccaaag
    26761 atatggatga aaaaggtgtg atcgacatgg aagttggtat cttctcgcat ccttacggta
    26821 gcactcaaga aacggaagaa tcgggccaat cggaagaaac aactgaaagt gaagaaaatg
    26881 cggatcaaac aaacgaatca agtgaagagg cagaaacgca aaaagcacaa acacctggat
    26941 cgtctagcac aaacggatca tctgattcaa atgattcaag tgaaacaagt caaatagaag
    27001 ataatccaag tacaactccg tcaagtttaa atgaaaattg ataaaacaac tttaaaaagt
    27061 aagaatgtac tttctaaaaa ccagtaattt atggtagaat tggaagcagt gaatatatct
    27121 attaataagt atattttaaa acggacgcta gttgttcgct tgtatatgga atagtaagta
    27181 ggagggaatc ccattcatgg caaaaacagg aatgtatgta ggccttgata ttggaacgac
    27241 atctgttaaa gttgtcgtgg ctgaatatat cgacagccaa atgaatatta ttggagtagg
    27301 aaacgcaaaa tcagaaggga ttaaccgagg cattatcgtt gatatcgata aaacggtcca
    27361 agcgatacaa cgagcagtac gacaagcaga agaaaaagca ggtatccaga tcaaaggcgt
    27421 aagtgtcggt ttgccagcaa acatgcttga agtagaaaat tgccagggaa tgattgcagt
    27481 taacggagat tcaaaggaaa tcaccgatga agatgtcaga aatgtggctt cagctgccct
    27541 tgttcgttca atacctcctg aacgtcaaat cgtgtcaata ttgccacaag attttactgt
    27601 cgatgggttc gagggaatca aagatcctcg tggaatgatc ggcgtaagat tagaaatgta
    27661 cggtctgttg tttacaggac ctaaaacgat catccataac atacgtaaat gcgtggaaaa
    27721 tgccggatta atcgtcaacg aaatggtgat tactccttta gcgctgactg aatcaattct
    27781 ttctgacgga gaaaaagatt ttggtacgat cgtcattgat atgggtggcg gccaaacaac
    27841 aacggctgtt atgcatgata agcaattgaa gtttaccaat cttgaccaag aaggtggcga
    27901 atttgtcact aaagatatct ctattgtatt aaatacgtca tttaacaatg cagaagcgtt
    27961 gaaaataaac tacggggatg catacccaga acggacatca ccagatgaag aatttccagt
    28021 agatgtgatt ggtcagtcag aaccagtgaa agtcgatgaa cgctacttgt cagaaattat
    28081 ttcagctcga atggaacaga ttttcaacaa agcaaaagat gcattggacc aaatcgaagc
    28141 attagagttg ccaggtggcg tcgtattgac aggcggagct gctagtcttc ctggtgttgt
    28201 ggacttggca caagaaatct tcggcgtaaa tgtaaaattg tatgttccaa atcacatggg
    28261 gctgagaaac ccggtattta caaatgtaat aagtatcgtg gattattcag caaacttgag
    28321 tgaagtgtat caattggcaa aaattgctgt tacgggtgaa acctcagcag ctcgtcaaat
    28381 ggtagttgaa caagaaacaa caaacacata tgagagctat gaagcacctg aagaaacaat
    28441 ctacgatgag ccggaaccaa aagagtccgg agaaaatgta aaaaataaaa tcaagggttt
    28501 ctttacaaat atttttgatt aattcatcct gggaggaata agatatggaa ttctcaattg
    28561 ataataatat caatgacggc gcagtaatca aagtcatcgg agtcggtggt ggcggtggaa
    28621 atgctgtaaa ccgaatgatt gaagaaaacg ttaaaggtgt tgaattcatt acagccaaca
    28681 cagacgtgca agcattaaaa aattcaaaag ctgaaacagt tatccaatta ggccccaaat
    28741 atactcgtgg tttaggtgct ggttctcagc cagaagttgg acaaaaagcg gcagaagaaa
    28801 gtgaacaatc cttacgcgaa gctttagacg gtgcagatat gattttcatc actgcaggaa
    28861 tgggtggagg aaccggtaca ggtgctgcac caatcgttgc aggtatcgcg aaagaattgg
    28921 gcgcattgac tgttggtgtc gtgacacgtc cattcacttt tgaaggaccg aaacgtggcc
    28981 gttttgctgc agaaggtatc gctcgtttga aagaaaatgt ggatacatta ttaattatct
    29041 caaataaccg tttattagaa gttgtagata aaaagacacc gatgcttgaa gctttccgtg
    29101 aagcagataa tgttttacga caaggtgtac aaggtatctc tgatttgatc acagcgccag
    29161 gttacgttaa ccttgacttt gctgacgtga aaacagtgat ggaaaaccaa ggtacagcat
    29221 tgatggggat cggtgtggct agtggagaag atcgcgtagt agaagcaacg aaaaaagcaa
    29281 tctcctctcc attgcttgaa acatctattg atggagctga acaagtactt cttaacatca
    29341 caggcggttt ggatatgaca ttgttcgaag cacaagatgc ttcagatatc gtagcaaatg
    29401 cagcaactgg cgatgtaaat atcattctag gtacatctat caatgaagaa atgggcgatg
    29461 aaatccgtgt gacggtcatc gcaacaggta tcgatgaatc aaaaaaggaa cgcaagtcta
    29521 gccgaccagc tagacaagca caaatgcaat cacctgctca aaagactgta ttagatatgg
    29581 atcaagctaa accaacttct tcagaagaag aaaacagttt tggcgattgg gatatcagac
    29641 gtgaacaaaa tgttcgtcct agagttgatg attccaattt tgacaatatc gaaaaaaaag
    29701 aatttgatac attcaaccgc gaagaaacaa aatctcatgg cgatgatgaa ttaaatacgc
    29761 caccgttttt ccgtcgtaaa aaataaagga gaggaagagc acatgattgc tgacaacttg
    29821 cagaaaatca agcaagaaat tcaggattcg tgtgctcttg ttcatcgtga tccgaaagaa
    29881 gttacattag tagctgtaac aaaatctgtt gaatccgctc aagctgaaga attggttaga
    29941 gctggcgtta tgaattgtgc agaaaaccga gtagataaat tattagaaaa gaaacaagat
    30001 ttatttgatt ttcctgaaat aaagtggcat ttaattggta atttacagcg cagaaaggta
    30061 aaattgattg taaatgaaat tgattacttt catgcgttgg acagtttaag attagcagaa
    30121 gaaatccaga agcggttaga gaaagaatta tcctgtttta ttgaagtaaa tgtttctggt
    30181 gaggaatcaa aacatggaat ttcaccagat gagcttttac cgtttgtgga atctttagct
    30241 gcctgcacaa aaatcaaggt tgttgggttg atgactatgg cgcctaaaga agcttctgat
    30301 gagcaaatcc ataaagtgtt tggtacgctg aaagaattgc gtgatcttgt tcaagcaaaa
    30361 ggttatgccc atgcaccatg tagtgaatta agtatgggga tgagtcaaga ctttcaaatt
    30421 gcgattgaag aaggtgcaac atttatccgt gtaggaacag cgctattcaa agacgaataa
    30481 aggaggaaca aaaatgccgc ttttaaacag aggagcaatt gctaattttt tcggattagc
    30541 tgatgaggaa gagtacgaat accaagatta tcctgaaaca acaaaaaagg ctgtacagcc
    30601 aactaaaaaa aatacaacac agaatcaatc aactcattct gtatctgctg cgaatactca
    30661 tgaaaaacaa aaaacggcga cttcacgtcc tgtaacgcat gaaagtattc agccggctga
    30721 aaagaaaaaa gtaattgaac tacatcaatc acctacaaaa actgtagcga aagaaagaac
    30781 agcttcaaga acctctacac aacctaaagc aaatcttgct ggaaaaatca ctgtaatgga
    30841 accaagagct tattctgaag ctatggcgat tgctaaacga atcattgctg gagaagcaac
    30901 cttagtgaat tttcatttag tagaagaaaa acaagcgaga agaatcgttg attttctaac
    30961 aggaacagtt tatgcactag atggagatat caaacgtgtt ggagatgaga tttttctttg
    31021 tacaccgact gggatggaga ttgacagttc aaccgctcaa tcttttgcag atgcgaattt
    31081 gtttgatctg taagaggagg aactacgatt tatactattg cactattact tcatttactt
    31141 caacgggcag cctatttcta tagcattatc ttgatggtat atgcattgct ctcttggttt
    31201 ccaggcgggt atcaatcagg gctaggacga ttattagcta agatctgcga accgtatatc
    31261 agtttgttcg atcgtctgcc tttgaggatt ggacccttgg atttcacaat tttaggggca
    31321 atcctgatct tgaacttagc cgtacaaggt ttagcacaga tcgttatatg gataactgtc
    31381 catttagttt attgattgaa gcaacaaaat ctttattctc agaatagata ggaggggaaa
    31441 attttggatg caaatgtata ccagcacttt cgggcagatg aacgtacatt tatcgattcg
    31501 gtaggcgatt ggattgaaca ggttcaagga caatatgcac cctatctgac cgaatttctt
    31561 gacccaagac aatcctatat tttagaaaca ctgattcgac aaagcagtga tttgcgtttc
    31621 atgttttatg gcggatatga acaggcagaa agaaaaagat gtttgatttt ccccgattat
    31681 tacgaacctg tagaggaaga ttttgaaaca gcattgtatg aaatccatta tcctagcaaa
    31741 tttgccagcc taagtcatgg gaaaatcctt ggaactttag tgggaacggg gatcaaacgc
    31801 tcttactttg gcgatatcat ctcggacggt gatcgctggc aagtatttat tgcaaatgag
    31861 gtggatcatt ttgttgctgc acaagtaaca aagattggaa aggttgctgt acgcttggaa
    31921 ccaatcaaat acacagaaat gattatgccg aaagatagct ggacacaaga aagaggaaca
    31981 gttagttcca tgcgactaga cagtgtgatc tctgagattt ataatatttc cagacagcgg
    32041 tccaagcagc tgatcgaagc tggtaaagta aaagtgaact ggacagaaaa tacaagacct
    32101 gattttgtac ttgaactatt agatattatt tcagtcagag gttatggcag agtccagatc
    32161 caagaacttg aggggaagac gaaaaaagaa aagtacaggg tactgttcgg tgtattacgt
    32221 aaataaaata aaaaggtggt ttactcatgg ctttaactcc attagatatc caaaataaga
    32281 cattcccgac aaaaatgcgg ggatataatc aagacgaagt agatgatttc ttagatttag
    32341 ttgttcgtga ctatgaggaa ttgactcaaa gaaatcgaga attagaaaaa gcagtcaaac
    32401 attctgaaga aaaacttgag tacttcaatg aattaaaaga tgctttgaac caatcaatca
    32461 tcgtagctca agatacggct gataaagtaa aaacaagtgc aagcaaggaa tccgaagtga
    32521 tcgttacttc tgcacaaaac aaagcagatg agttagttgc gaacgctgaa aaacgtgcac
    32581 atcaattaac aactgatgca gaagaaaaag caagaaaaat cttgacagat gcaacagaaa
    32641 aagcaagaca gcttgcgaca gaaactgaag atcttaagaa aaaaacacga gtattccatc
    32701 aacgtatcag cttgatgctt gagtctcaat tagaacaagt gaaaagtccg gaatgggatg
    32761 aaattttaca accattctcc agctacgtga ctgacagcca tgaagtgatc aaagaagttt
    32821 tagcaaaaca gcttgacaat gaaaatgata ctgatgtaaa ctcagacaca ggagtcatag
    32881 aagcacctat gacggcattt gatacacagg ctattgatat ctcgatcgtg cctggtgaaa
    32941 atgaaaacga gtagaacaga aaagcacttt gttattctta aagcgagccg atgagagtgg
    33001 aagttcggta agacactgca tggtgaaaga tcctctactt gagacctgct tttccgaaat
    33061 tagagtaaga agcagcggct gacctcgtta ttggtcacag agagtttgca ctagatagat
    33121 gcaactaaat ttgggtggta ccacggcatg ttcgtccctt gcggctgaac atgctttttt
    33181 gtgtccggaa aacaaataaa ggagtgtatg gttgaatgaa aatgaaagaa accttgcaat
    33241 taggaaaaac aaaattccct atgcgtggta atttgccaaa ccgagaaggc gagtggcaaa
    33301 aagaatggga agaaaatcga atctaccaaa aaagacaaga gttgaacgaa ggaaaaccta
    33361 gctttgttct tcatgatgga cctccatatg ccaatggtaa tatccattta ggacattcat
    33421 tgaataaaat cagtaaagac attatcattc gttcaaaatc aatgtctggc tatcgtgcac
    33481 catatgttcc aggatgggat acacatggat tgccgattga acaagtattg gctaataaag
    33541 gcgtgaaacg taaagaaatg tccatggcag aatacttgga aaaatgtcgt gaatatgcac
    33601 tttcccaagt agataagcaa cgagcagatt tcaaacgcct aggagttgca ggagattggg
    33661 aacatcctta tgttacatta gatccttctt atgaagctgc acaagtacgc gtatttggta
    33721 aaatggctga aaaaggctat atttacaaag gattgaaacc aatttactgg tctccgtcaa
    33781 gtgagtcttc tttagcggaa gctgaaattg aatataaaga tgtaaaatct ccatctattt
    33841 ttgtagcttt caatgtcaaa gacggcaaag atattcttga tgaagataca gcttttgtca
    33901 tttggacgac aacaccatgg acattgccag caaaccaagg tattgctgta aatccaaaat
    33961 ttacgtatgt attggtggaa gccgatggcc gtaagtttgt cgtagcgaaa gatttgctag
    34021 aaacagtcca atcagaaatc ggttgggaaa atgtaacagt tctaaaagaa tttgctggac
    34081 aagaaatgga atatatgact gcaagtcatc cattctatga acgtgaatca cttgtgattt
    34141 taggcgatca tgttacttta gacgctggta ctggattagt ccatactgct ccaggacatg
    34201 gggaagatga ctatatcgct ggtagcaaat ataaactatc tgtagtgtca cctgtagact
    34261 caaaaggatt gtttacagaa gaagcacctg gatttgaagg tatcttttat gacaaagcaa
    34321 atcctatgat cactgatcta ttaaaagaaa aaggagcttt gctgaagcta gatttcttta
    34381 ctcatagtta tcctcacgat tggcggacga aaaagcctgt gatctatcgg gcaactccac
    34441 aatggtttgc atctatcgat aaattccgtc agaatatttt ggatgaagta gaaaaagtag
    34501 agtgggttat cccatggggt aaaacacgtt tgtataatat gatccgtgac cgcggcgatt
    34561 gggtaatttc ccgtcagcgt gcatggggag taccacttcc gattttctat gctgaaaatg
    34621 gagaagcaat catcacacca gaaacaatcg aacatgtggc aaaattattt gctgaacatg
    34681 gatcaattat ctggtttgaa aaagaagcga aagaacttct tcctgaagga tttacccacc
    34741 caggttctcc taatggcgaa tttacaaaag aaaaagatat catggatgtc tggtttgatt
    34801 ctggttcttc tcatgaagct gttttacgtc agcgaccaga attatcattc ccagcagata
    34861 tgtatttaga aggatcagac caatatcgtg gctggttcaa ctcaagtatc acgactagtg
    34921 tggctatcaa tggtgtagca ccatacaaat cagttatttc tcaaggattt gctttagatg
    34981 gtgaaggccg taagatgagt aaatctttag gaaacatcat tgcaccagaa aaagtgatca
    35041 aacaatttgg tgcagatatc cttcgcttat gggtatctag tgtagattat gaagcagatg
    35101 ttcgtgtttc tatggatatc ttaagtcaag tggcagaagt atatcgtaaa atcagaaata
    35161 cgatgcgttt cttattagcg aatacagaag atttcgatcc taaaaaagat actgtttcgt
    35221 acaatgattt acgttctgta gacaaatata tgaccgttcg attgaaccaa gtaatcaaag
    35281 aaatccgaga agaagggtac gacaaatata acttcatgca tatttaccgt acagttatga
    35341 acttcttgac ggttgatcta tcgtcattct acctggattt tgctaaagat gtagtttata
    35401 ttgaagcaga agatgattat caacgtcgtt gcatgcaaac tgttttctat caaacagctg
    35461 tagctttgac aaaattattg actcctatca ttccgcatac agcagaagaa atctggtcat
    35521 tcctgaaaga agaagaggag tacgttcagt taagcgagtt tcctggttat gaagagtttg
    35581 caaaccaaga agaattgatg gatacctgga ctgctttcat ggacttccgt gataatgtct
    35641 taaaagcatt ggaagaagca agaaacagca aattgattgg taaatctttg gaagcaaaac
    35701 taactgttta tccaaaacaa caagttcgtg aaatgttaaa agctttggat gcagatattg
    35761 cacaattatt gatcgtttca ccagactact ttgaagttat ggcagcagat gaacaagtgc
    35821 cagataacgc tatggtattt gatgatgttg ctattacagt ggaaaaagca gacggggaaa
    35881 cttgcgatcg ctgtcgccaa gttcgtaaag atgtaggagt agatgaaaaa cttcctcatc
    35941 tatgcggtcg ttgtgcaaaa atcgttgaag acttctatcc tgaagctgta gctgaaggat
    36001 tcgaagaaaa gtaaaaggga aaagggggtg tgacatgttc tttgtcacac ccccttttgt
    36061 tatcaatcgt ttaattttcc acgttcacga taccagttat ctggttgcca gatccattcg
    36121 aatccgtctt tttcaagtag ttcgaaagct gctttaggtc ccattgatcc agctttgtag
    36181 ttgggaaaat ccggttgtgt ttggtcccaa gcttttcgaa tgacatccac gatatgccaa
    36241 gattgagcga cttcttccca atgagagaag ttcgttccat caccattcaa cgcatctaat
    36301 agtaattttt cgtaagcttc tgggctattt tcaaccattt ctgcactatt tctaaattcc
    36361 aatttgattg gttccgtttc aaatccttgc cctacttctt tcccattcaa ggataaagaa
    36421 aatccttcag ttggctgaat atagatcgtt agaacattag gtggaagtgt cgtatcgtca
    36481 catggttcat cgacagatgt tttgaataca ttaacaggaa cttgtttgaa tacgatgttg
    36541 atccgagtcc ctttttcagt caaacgtttg cctgtacgta catagaaagg aacacctgac
    36601 caacggaagt tatcgatagt gaatttgcct gcgacgaatg tttcagtctc tgattgagca
    36661 tccactttgt cttcttcgcg atagcccttg aattgtacac catccaattc accttgagca
    36721 tattgcccgc gaacgaagtt ttctaacact tcttcttcgt tataaatgcg gatagctttc
    36781 aatgctttga tcttttctgt acggatttct ttttcggaaa atgctactgg cggttccatt
    36841 gcaagtaatg ctacaacctg taaaatatga ttttgcacca tgtctttaag tgcgccacta
    36901 tgatcgtagt agcccccgcg atcttctaca ccgaggtttt cgccaaaagt aatttggata
    36961 ttgtcgatat agcgattgtt ccattgagcc tcaaaaatat tattggcaaa acggatagct
    37021 gagatgtttt ggatcatttc ttttcctaaa taatgatcaa tcctgaaaat atcttgttct
    37081 gggaatactt ctctgatttg ctggttcaat tcaaaagcag actggtaatc agaaccgaac
    37141 ggtttttcta tgatcaaacg attgaagcca ttttttgtca taatattttg tgatttcaaa
    37201 tgagaaacga tcgttccaaa aaattgaggt gccatagcca aataatagac acggttaccg
    37261 tttaattgat agtgtccatc taatcggtca gacaattctt ttaatgtctg ataatgcgtt
    37321 gaatcattta catcatggga ttgatagtaa aaatggcttg caaaggtagt tgcttcttca
    37381 tctgaaggat tcaatgcacg gattgtttct ttgacaactt cacggtagtg ctcatcgctc
    37441 cagggacggc gagcggttcc gattacagca aaatgctcgc ctaaatttcc ttttctgtaa
    37501 aggcggaaca aagacgggta caatttacgc tgggctaggt cacctgtacc gccgaatatc
    37561 gtaaacaata catttttttc attagacatg tggatacact cctttatatt ttatcgacaa
    37621 aaatcgtgct ggccgcctta aagctgacgg ggattttctt tctatcattt tggatagtga
    37681 tcggtccttc ataagctgcg atgtcaacga tctcatattc ttcgttgata ttcaggtcaa
    37741 tagtgactaa gtaatccaac aattcttttt catcaagcac tcgtgcgata cgcacttttg
    37801 taccgacagg ataggactcc aatgtttgtc ggcgttcttc atggacaact tcctcttttt
    37861 taggaatcga tcctccatga ggacaatgtt caggatgatt caaatagttt tctaaatgat
    37921 ctgcaagatg ttccgaagtc acatgttcca atacttcagc atcatcatgg acttcattcc
    37981 agctatagtc taaatgttca actaaaaaaa cttcccataa gcgatgtttg cgaatcagac
    38041 tgctagcttt ttgcagtccg cttgcagtca attgtacacc ttgataaggg gaatgttcta
    38101 caagctcttc tttcacaagt ttagaaatca tttcactgac agatgcagct gagacatcta
    38161 gactagatac gatttgttta ttgttgactt tcgttgtatc tccacctagt tctaaaatga
    38221 ttttcaaata atcttctcga tttggtgtca tattcgatca tcctttcatg gtaaaaaacc
    38281 atcattagta agtgtaacaa aaaaaacgtt aattgactat ttttctaaat aaaaaacaaa
    38341 ggatttttag acgtttttac aacaaaaaac gaaagatgat agagaagact cattctttcg
    38401 tttataaagg atatatatat acattgggag ggatctattt ttcagataac aacttatatg
    38461 aagtgtctgc agattcgtca taaagagttt gttcgggata agaaaagata agataaaaac
    38521 catactgatc acgtacgact aaacgatatt catctatttc taccacagat gtgccaagag
    38581 actgaccgtt gatcaaaaac gtgtaatcag atgtaatctg taattgttgt ttttgctggc
    38641 tatcactaaa gaaccatgta ccttgatact ttgagagtcc ttctgacttt tccgcttgtt
    38701 ttttcttttt caagtaaata aaacttgaga gaacggtaat gagtgaacca agaaaataga
    38761 tcattttttt tatcaccaaa tcactccttt atgagaaaat aatcgcatag acatattctt
    38821 tcttctttat ttcattgtac cgaataaaag ctaaaatttc tctaagactt tcgactggtt
    38881 tttttactgt ttttctacaa attatgatag gatacatagt aggaagaaag gtgacataat
    38941 ttgaagtatc agcaagtgga aatagctttt tttattgacc gcccgaatcg gtttatagca
    39001 cattgtatga aaaaagacgg agaaataatt attgcgcatg tcaaaaatac aggtagagga
    39061 aaagaggtcc tgataccagg cgctgaagtg gctattgtat ttgctcctgg acctaaacgg
    39121 aaaaccgcct atgatctgat tgctgtaaaa aagaagggtg actggtttaa tatcgatagt
    39181 caattgccta atcggctggc aattgatggt attttagacg gcacgatcct tttaccagga
    39241 ttaactggtc catttacggt atacaagcgt gaagtaactt atcttcactc caaatttgat
    39301 atttatttag agacggtggt cggacaaaaa gcatttgttg aagtcaaagg tatgacactt
    39361 gaaaataaag cgattggtgc ttttcctgat gcgcccacac tcagaggatt gaaacatata
    39421 ggagaattaa cgtatgccgc acaagatggt tatgccgctt atgtcttgtt tattgctcag
    39481 ttcgaacatc ttcatctggc aacgatccat gaagaaatgc aaccagcact agctgatatg
    39541 gttcgacatg cgcagcaaag cggagttcaa atcctcgcct ataattgtca agtatcggca
    39601 gatgaggtaa ctgtcaagca ggccattcca tttgatgtag atatcccttt tgaagatcct
    39661 atacaataga aagaaggtaa aataatgatc aacttaggta ttatcggaac aaattggatt
    39721 actcatcaat ttgtccaagc agctttaagc acaaaaaaat atgaattgac agcggtatat
    39781 tctagacatt tggaaaaagc acaggaattt ggttctcatt atgaagggga tatcgaattc
    39841 gcaacagatt tgaagacttt tttcaatatt actcatatgg acaccattta tattgcttct
    39901 ccgaatagtc ttcactttag tcaagctaag caagcaattt tggcaggaaa aaatgtgata
    39961 gttgaaaagc cagctttttc gacgccaaaa gaaatggatg aaatcatcca tttggcaaat
    40021 gaacacaatg tgtatttttt tgaagcagca agaaatatcc atgaatcagg ttttaaaaag
    40081 attgccgatt acttaccatt aaaagacgag ataatcggtg caaatttcag ctatatgaaa
    40141 tattcttcgc gctatgacca agtattagat ggagaagaac cgaatatctt ctcgactcat
    40201 ttctcaggtg gtgcattgat ggatttaggt gtttaccttg tatatgcagc tgttgcttgg
    40261 tttggaatgc caaaagaagt ccattatttc ccaagaaaga tttctactgg tgtagatggt
    40321 cttggatggg ggatcttacg ttatgagaat tttgatgtat cgatccagcc aggtaaaatc
    40381 ggtgattctt atttaccgtc agagatttat tttgactcag gaacgctagt gatgaatgga
    40441 gtcaatgcaa ttgaacaagc acaatttcat gatcgcgcgc ataaagaaat cattgatttg
    40501 gcggtaacag ctgcagaaaa tccaatggca gatgaagcag aggattttgc caatgtcatg
    40561 gctcatccga aagatccagc ttggggattg ttgtatgaag agtggatcga gctagctaga
    40621 aatgtgaacc aagtgattta tgatttaaga aaaaatggcg gcatcaaatt cgatgcagat
    40681 aatgaggaag atttttaatg aacgaatttg tacaagtatt tcccgaaaat tggcagaaaa
    40741 aatatgagga taaagggttt atctcacctt ctcttattca acgagcagtt tttcagccac
    40801 taagtaataa acaaagtata gtagcggttt ctcctacagg ttcaggtaaa acactggctt
    40861 atctttggcc tctactacta aacgtggaac caggtgaagc aagtgcgttg gtcatttttg
    40921 cttcttctca agaactagct attcaagtag cagatgttgc acgtgaatgg ggaaaagaca
    40981 aagagttgaa agtccaatct ttggtgggcg gagccaacgt caaacgtcag attgagggtt
    41041 tgaaggaaaa accagaaatc ttgattggta caccaggaag aatattggaa ttgatgaaag
    41101 caaaaaaaat aaaagcacat caagtgaaaa caatggtatt tgatgaagca gaccagctat
    41161 ttgacgctgg gaacagccaa atcattgatc aaattcttca tcaagctcca acagagtatc
    41221 agctagcttt tttttcagcg acagcagatc gttcccttga aagcattgaa aaaatcactg
    41281 ggaaaacgtt tgagacaatt gacgtgacag cagaggacga ttctcgaaaa ggactgagac
    41341 attacttttt acgtgtaccg atacgaaaga aagatgacta cttgagacgt ctcacgcata
    41401 tagaagattt tcatggtctg attttcttta atcaactgac tgaattaggc gtaatggaag
    41461 aaaaattgct gtatagaggt gtaccggtag gaagtctggc ctctgatcag aacaagctac
    41521 tccgaaaagc agcgctagaa caattcaaaa agaaaatggt cagagcactt ttgaccacag
    41581 atgtggcggc tagaggttta gatattacag gtcttcctta tgtagtgaat gcagaagttc
    41641 cgttaagtga agaagcttat ttgcatcgtt cgggaagaac tggtcgaatg ggtaatgaag
    41701 gaatagtaat tacactcgta caagataata atctaagaga tttaaaacgg cttttacgtc
    41761 catcaaatat aacacttgaa gagatttttt tatacggagg taagctgcaa actgagcagc
    41821 caaccaaaga agatgcagct cctgcagtaa ataaaaagta tgcgaaaact ttttctggaa
    41881 aggagcagaa cccagaatat aacaaagaaa aaataagaaa aaaagttaaa aataaatcaa
    41941 aaaaagagag aaataaagga gcaaggcgca aataagcgcc tttttatgct atgattatga
    42001 aaacgggaac aaaattggtt gccagaggag gggttatgtg aaagaacgtc aagaagagat
    42061 cttgcagcta ttgacagaaa accaacaagg attgacagca agtgatgtag ctgagcgctt
    42121 aactatcgat cgaagcaatg caagccgata tttaagtgaa ctatacaagg cccatcatat
    42181 tgtaaaaacc gctggccgac cagtcgttta ctctttgcca acggaaaagt caaaatctga
    42241 tgaagtgcat gtcgactctt ctacgcaagt gacttttgaa acactcgttg gagaaaatga
    42301 ttctttaaaa gtcagcatac agcaggcaaa agctgcgatt ctttatccac cgcgggggtt
    42361 gcatacgatt atttttggag aaactggtac agggaagtcg atgtttgctg aatgtatgta
    42421 tcattttgca atcgattcag agatgctttc tgcagatgcg ccatttgttt ctttcaattg
    42481 tgcggattat gctcaaaatc cgcaactgct ctttggacac atctttggga tcaaaaaagg
    42541 ggcttacaca ggagcagctc aagatagtcc cggtctaata gccaaagcag acggcggtat
    42601 attgttttta gatgagatcc accgtttacc gccggaaggg caggaaatgc tgtttacttt
    42661 cattgataaa ggtatttacc gtccgcttgg agaaagtgca caagtacatg aagcatctgt
    42721 tcagatcatt ggggcgacga ctgaatcttc agaaagtttc ttatctacgt tcaatcgacg
    42781 gattcctatg gcaatcacct tgccgaatct tgcttcacgt tcactggatg agcgttatga
    42841 aatcatctct ctttttatca aacaagaagc gaatcgtttg aatcaacgta tcgatatcga
    42901 aaaagaagcg attcttgcct tcatgcttta tgatgcggaa ggaaatatcg gtcaagtgaa
    42961 acgagacttg aaactagtct gtgcaaaatc ttttttacat taccgtactc atcatgagaa
    43021 aaagctaatc attcgaaaag aagaactttc ccttcaagta caaaaaggat tactgaaaat
    43081 caaggaaata ccggaacgtc tcgaccgatt catggacagc aaaagtcagt atttgacatt
    43141 tgaaccagga tttgctgatg ttgtctggtc acaagatcca gaacgaaaca tgcaggtcta
    43201 taacgatatt gaggaaaaag tcacttctct ttccgaaacc ggtgtggaga acattgatct
    43261 agagaccctc atttcaaaag atgtggatgc ttatttccag acatatgtca aagaattgac
    43321 taaaagttcg attcccaaag atcttttgcc agatgaaatc tggcggttaa ccaatcaatt
    43381 gtatgatgtg gctgaaaaac ggttagaccg tatttataat gaaaaagctc gttttgcttt
    43441 tgctttgcat ctgcaaagta cattggatcg tgtgagagaa ggtcatatga tcgtccaccc
    43501 agatttgaat aacgtacgga aaaattttaa gagggaattc caggtagcaa tcgatctttc
    43561 aacgatcatt gaagaagaag aacaagttga gattcctttt gatgaaatcg gctttattag
    43621 tatgtttctt tctatcaatc taggagaaag tgagcctgtt aaagaaaaca aagtagatgt
    43681 tctcatattg atgcacggca gacagactgc ttcaagcatg ttggagatgg cacaagaact
    43741 attaggaaca aaagtaggga aagcttttaa tatgccactg gttatggaag ttcaaacaat
    43801 gtatgaagaa gtgttacaat atgtcaaaaa ctatcaagag catttgacga atggcctact
    43861 cttgttaaca gatatgggat cattaaacac cttcagtgat ttgatttatg aagagactgg
    43921 cattcggacg aaagctatca cgatgacaag taccatgatt gtgatagaag cgatacggat
    43981 ggcaagtgtt ggaagaagct tagaagatat ttatcaaaat atccagcttt cctttgaatc
    44041 gatcgtacgt gatcagttca aagcggaaaa gtctgaaact ttacagcgta aaaaagccgt
    44101 aatcgtgaca tgctttactg gtgaaggagt agctgccaaa ttatatcagc gtattatgcc
    44161 agtgattaat caaaataagg tagaactgat ccagatgcag tttttagaac gtgaatcatt
    44221 caaaaaacac atcgatgcct tattggaaga atatgagatc aaagcaattg cgggaacagt
    44281 tgatgttgat tatcaaaata tcccattttt ttcagcctat gacgtttttg atgatgaaaa
    44341 actaaatatt ttaaagcgta tagctgatga tgagatcccg acagctaaaa ttgtcgattc
    44401 acttgctgga tcattaagcg atgtcttttc tattgatgaa ctgatccgtt cattgcaaaa
    44461 gacagttcag cagatccaga ccgatttgtc gattatcgtg gaacctggag tagatactgg
    44521 aatcgttatc catttagcct tcatgttaga cggattgatc aaacaagaaa gccatcggca
    44581 atttgagaaa ctgtctattt tctcaaaaat ttatcgtttg gaaatggata tcgttcgggc
    44641 aaacttgatg gcactagaac gaaaatatca ggtaaaaatt ccagaagatg atatcgcatt
    44701 tcttacacaa atgtttcttg aaaataaaat aaaaaaatga acacactaat catactgttt
    44761 acacactaaa catctgtgtg cgcactataa aaaagagcta aaaagcatga aaacgctatt
    44821 tcagctcttt tttttattgg catgcttctt gcgttatata aaagtgtaaa aaaataaaag
    44881 gagtgttaaa aatggcaaaa aaaacaatca tgttagtttg ttcagcaggg atgagtacga
    44941 gtttattggt cacaaaaatg caaaaagcag cagaagaaaa agggatggaa gccgatattt
    45001 ttgcggtctc tgcctcagat gcagataata atttagaatc taagaatgtc gatgtattat
    45061 tattaggtcc tcaagtacgt ttcatgaaag ctcaatttga acaaaaactt gcgcctaaag
    45121 gtattccatt agatgtcatc aatatgcaag actatggcat gatgaacgga gaaaaagttc
    45181 ttgcacaagc agaaaatcta atgaaataaa tcaagtatgc agttgggggt ataacaacgt
    45241 ggaagatcaa caaaatctag aagccatcat ggggttaatc atgtttggcg gtaatgcaaa
    45301 gagcgatgca atggaagcga ttgcggctgc taaaatcggt gattttgagt tagcggatag
    45361 gaaaatcgct gatgcagaag aatcacttat acaagcgcat catgcacaaa cagacatgtt
    45421 gacacaagaa gcacaaggaa atcatatgca agtgacatta ttgactgttc acagtcaaga
    45481 tcacttaatg acatctattg cgtttactga tttagcaaaa gaaatcatcg aactttatcg
    45541 tcgcgtatac agcgaataaa tacaacttct tttttgaacg gaagaagaaa aatttttgaa
    45601 cggatttttt attttgttat aaggagaact ctctttatat aaaaaactta taggaggaag
    45661 taaaaaatga acggactatc aagttggatg gagaaataca tcctgccggt tgccgcaaaa
    45721 atcggagcgc aaaaacattt agttgctttg cgtgatgctt ttatcggcac actgcccgca
    45781 acaatggcgg gatcagtcgc tgtaatgatc aatgcaatta ttcgtgattt accgcaacag
    45841 tttaacagta cctatgctga cagtttagca gcagacaaag gaatctttgc cgtattgaat
    45901 gtcatcatcg gaatcaatgg ttttgtctgg aacggtacac tagcaatcgc cggattgatc
    45961 tttgcctttt cttgggggta taatcttgcc cgagcttatg gagtaaatga tctagctggg
    46021 gggatcgttg gtttagctac cttgattcaa ggtatttcct ttggtccagc attatcagca
    46081 gcattagatg tgaatgttcc ttcaaatgtc gcagatgcaa tcaatagttc tgagattggt
    46141 gcaacgattg cagatggcac actgtcagtt ggattatggg gttggctaaa actagatcat
    46201 ttgaatggaa acgcttattt tacagttatg atcatgggag ctatttcagt cattattttt
    46261 tgtaaattga tgcttgccaa cattacgatc aaaatgcctg attcagtacc accagcagta
    46321 tctaaagcat ttgcagccat tttaccagcg acgatcgctt tatacgtcat tgctattatc
    46381 aattatatcg taggtcgtgt agctgatggg caactgatca ttgatttggt gcaaaaatat
    46441 attgcagaac cattcctagg attatctcaa gggttgggag cagtattgat cgtcacagta
    46501 tttgttcaag tattctggtt ctttggtatt catggaccaa atgtattggc accagtgcta
    46561 gagggaatct ggggacaagc acaactaatc aatattgata ttttccaaaa aggttataac
    46621 ggaaaaactg gtacaccagc cgtgttagat gcaatcgaag atggaaaagc ttatatgtgg
    46681 gtccgcggat cgttcgatgc ttttgcatgg tttggcggat caggcggaac gatcgtctta
    46741 ctgatagcta tcttgatttt ctctaaacgt gcagattatc taacagtagc taaattatcc
    46801 attgggcctg gtatcttcaa tatcaacgaa ccagtgatgt ttggtctgcc aatcgtattg
    46861 aatgcaatca tgtttatccc attcttgatt gctccagtag tagcaacagc aattggatgg
    46921 acagctactt atcttggcct agtcgctccg gtatcgcagc aagtcacatg ggtagtaccg
    46981 ccgttcttat tgtcattctt agcaacagga gcggattggc gggcaccgat cgtaacatta
    47041 gtatgtatgg tcgtgacttt cttgatttgg gcaccatttg tcatctctgc aaacaaaatg
    47101 gaccctgccg caggcgaaca acaataagat gaacgtgagg agcgggacgc tttaagtttc
    47161 gttcctcata atgaattttc taggaggaac tgaaatgatt acaattgcca gtgcaatgca
    47221 acaagatgaa atcaaagaat tgttagaagg atacaatgaa gaaggaatga cttttacatt
    47281 taaagaaaaa caaggaatca agctgttctt tgaaacaagt gcagaagatc cggaagttgc
    47341 ggctaaaaaa gcaaaggaac taatcaaagc acagccttgg ggaacagtcc tttattttca
    47401 atcaacagct gtttagaaaa tggtttaaaa agataggatg gttgagatga taaaaaacgg
    47461 tttattttta tgtagtattg gttctttgat cgtgttgtat agtttgaatc cacattcgca
    47521 aaggtatgat ttgtatagta tggtcacagg tctttttcta acaggattag gaatctattt
    47581 cttcatgaag gggaaaaaaa gagaagaagc aaaggagaaa aataactaat ggaaatcacg
    47641 aaaaaattaa atattccagc atcgtttttt tacgataaag ttatggactc tgtccttttc
    47701 gatgtacgta aagcgaccgg caaatcagta actagaaaac agctgaaaaa tttggagtac
    47761 gtcaaacaat tctcgcaaaa taaccgggct cgcataaaaa tcgaagaagt cattgaaaac
    47821 cagtcttata agtttcgtac atcgacaacg aagaatgaat tcgtcgttca ttatcaaatc
    47881 aaaccattgg acgattcgac ctgtgaggtt cattacacag aaaaaatgga gtcttatggc
    47941 atgcttcaaa agttgaatga tatgctttta ggaacaatct tgatgtattt taaacggaga
    48001 cgtttcaaaa aaatgctaga tatgatcgaa gcaacgtatt aaatcaatga aacatggtac
    48061 tatttagtta ttgaaaaatg aagtaagcta gaaggaattt ttcataggaa gatagatctt
    48121 tcctgcgaat cctcactagc ttttttgtag gaaggggcag caaaatgaca aacaaagtaa
    48181 gagagctagg tgtatcttcg attgaggaaa tgtttgattt agccacttat gcatttaatg
    48241 gggcagatac acctgaaagg cgagaacgtt ttcgtacact tgcggagaat tcttggaatt
    48301 acggattttt tgatgaggag gatcggctaa caagtcaagt catggcgacc ccttttccag
    48361 tgaattttta cggacaagag tacctaatgg ccggcattgg ctatgttgct tcttatccag
    48421 aagcaagggg acaaggcggg atcaatcaga tcatggaaaa gatccttgaa gattgccgtg
    48481 atcgtaaagt aagcttatct tatctggcgc cattctccta tcccttctat cggcgctatg
    48541 gctatgaaca atcatttgat aaaatcagtt atcaactaaa cagtcgtgat gtgccgttta
    48601 tcaaaaaaaa atctggaaaa ataaagcgta tggattttga agatgcaaaa gctgcaatca
    48661 gaagaattta tgaacagatg ccggaaaacc aacgagctgg tctgaagcgc gaagactggt
    48721 ggtatacgta taaattcaag caaaaaggca attaccagtt tgctttgcat tttgatgata
    48781 atgaggaagc aacgggatat atcgtttatc agcttgcaac gtcttccttt attattgcgg
    48841 agtggggatt tttggatcat gatgcttttt gcagccttgt tcgcttcgta agttctcaca
    48901 atggtgcttt tgaaacattt gaatattcat gcggctacgg cggtaatgat caaaattatc
    48961 tattagaaaa tccatttgct tctgtaatga tcacacctta tatgatggcg aggatcgtag
    49021 atatttcttt gtttttggaa aattatccat ttaaaaagag acaagctgca tttgccctac
    49081 aaatagaaga agatcattat gcgaaatgga atgaaggaat cgtggaagta acaatcgaaa
    49141 atggaaaaaa tcatctctca aaagtagaac aaacaaaact cccaatcgtt cgaggaagta
    49201 tccaacatat cacgcagcta ttattagggt atcgtaaagt ggaagagttg gtattccaag
    49261 aaagaataca ggtgacaaaa gaatatgaag aaacgttaag ctcaatcttg ccacagcaac
    49321 agccaattct taatgactat ttttgataaa aaacgggtga tgacaatatt tttgtcacca
    49381 cccttttgtt tttcatttgg catttgaagg aaaatgttaa agtaaatcct cttttttcgt
    49441 aaatttgaat tttttgtttt cttttgtttt agggttttct tttttgtggt cttggattgc
    49501 ttctttcgta atcttttccc gatttttttt agatgaatct aagcgttctg cgtatacttt
    49561 ttcttttggc ttatcattca ttggaaagga cctccctaca ttatttcatt ctacctctag
    49621 tttatcatct gttaaggact agtggaaacg ttttgcctaa cttataagct gattttttta
    49681 gcagataagc ttgcaagtaa aaaacaaaca agctacaatt gatttattga aattgttcct
    49741 gtagctcagt aggatagagc aatcgcctcc taagcgatag gtcgctggtt caattccagt
    49801 caggaacgta taaataaccc ctgtatcctt tgcggtacag gggtttgttt tgtatttgtg
    49861 ccaaaaatgt gccaaactag ttatcatttt tatataaact atcgaacaca gtattgattt
    49921 tttctttatc ctgatcttca agctctcgaa caatatgaag ataagtagac attgtagttt
    49981 ctaaactgct atgtcctaaa cgtttcgata cgctaagtat atttactcct tgataaagta
    50041 aaatagatgc atgtgtatgc cttagtccat gcaaagtaaa ttgcttttca atccctaatt
    50101 cttttaattt tttgcgcaaa tatttgctga cggcgtttga tgaaactaat ccatttttta
    50161 agttgaaaaa aacaaaatta tgagggtttt tgatttcaaa attctcgaat aattcttttt
    50221 gattgatttt aaactttttt aagagatcaa tcgtatgttt atcaatggaa attttcctat
    50281 ttgaagtttc gttttttgtt tttccccatt catttaattt ataattccat gttttattaa
    50341 tagtgatgat ttgatcttcg aaatcgatat cttcccatgt taatcctaga agttcagcaa
    50401 atcgcattcc agtggcacca gcaactaaca cgagcatagg agaagagtac tgcgcagaaa
    50461 ggttttcttc tacgagtttc attaaagatt taaattgatc ataatctaaa tatttatctt
    50521 cttttggctt caatgaatct tttcctttga ttactgcttt tctagttgga tcaaacggaa
    50581 ttaatccttc ttctacggca tctttcaacg acgctctaat atggttatta aacttaataa
    50641 cggtagattt tacatggtct ttagcatact tatttaaaaa gcgttgatat cccactctat
    50701 ctaaatcaga aatcaatacc gctggcatat atttctttat gttcattaac gtatcttcgt
    50761 attttctata agtgatagga gatactgttc cttctttata aagttgcatc caatcctcaa
    50821 agtaatctga taataataga tttttgcgat cccctttaag gcctttgttc aagttatatt
    50881 ctaattcgtt ggcggcatct tttgcttctc cttttgtctt aaatcctgat tttcttatct
    50941 tcgtgtattt tccgtcatct tttttgtatg aaatttcgta ttgccaacta tttccacgtt
    51001 tgactaatct tgccataatt gaatcagctc tctttctctg atacaatagg aactataaag
    51061 aagcccattg tttgggtttt attatttttt gcacatcctt tttgcttgcc ggcgcaagga
    51121 tgtgctattt gtcgttttaa tggtataatt ggatgtgtat tagatcatcc aatcagaggt
    51181 gtttattatg attaaagtga tttttaaaag aataactgaa cttccagagt ttagattatt
    51241 tgttgattat tggtatgtct ggttttttat tgttgcattg ctgataggtc tagatgtcat
    51301 attagaaaga aaacttaagt aagagttgag ttaataaatt gaattcctaa atgagatatt
    51361 ttgtagccca tattttgttt gccgacatca cctaatacta tggagctaat cgttttttct
    51421 aacagaccaa aatcagataa tctatttaag ctaccatcta ttagctcttg tgaatagcca
    51481 gacatgctga tatttccagt gaaattttcg tttccacgac tcattaagca tgctaacaat
    51541 tgaatctcaa tcgatgttaa ttgattcagt acaagaagat aatactcctc gttatcccat
    51601 gaagcgctgt taattcgaag taaacaattc ttataaagat ttttatacat atctatttta
    51661 ttttgtgcct ttgatttttc tacctcgtca tttatccctt cgaatattcc aatgagttgg
    51721 tccttgttct ctaagttgaa aacatcttct ggaatttgat cgcgaatgtt ttctaatgat
    51781 tcgtttaaat ttttgtagaa tttctcgatg cgtttgaaac gcttctcgtt tttagaccca
    51841 aaataaagtg actgcacaac gccaccaata taaggaattg ctccaatacc gccttcaact
    51901 attaattcaa gatattcttt tttggttagt ttttcattgc tattatccat agttacctcc
    51961 tattttgtca tttcctttac aagcattgtg actcctgatg gcactctttt gtataggttt
    52021 tattattgtg cacaatctaa ctcttagtgg ggcgtggttc atttattttt tacttacttt
    52081 actattaatc atatcccatt gagcatagga tttttctatg ttcgatcctc ttgaactaat
    52141 ttctcctgta aaagttactt tatcgccctt tgtaaaggta tcagcattgt ttaagtcctt
    52201 cgcaaaaatt acatatgaaa ctttaggtgt tgcagaaata tcattccaac ttttatcatc
    52261 gtactctttg tctgctataa tggctattct agtagtcatt gattcgataa cagttccttc
    52321 aaaagtatat gttttaccac taatatattt agtaaaagct gtattttgct cagtagctgg
    52381 agtaatagaa taataactat ctaagaaagc accccagtca tgattatttg tctctaaaaa
    52441 ttcttcaaat tgagttaggc ttttattgct gctgttagat gtagtagttt gagtatcaga
    52501 tgatgagctt tcctgtttgt tattgtcatt tgcctcgttt gatgaggaaa gcgagaaacc
    52561 tacggtagta aaaataatcc cgataataag gagaatcata ggtgttttct tatttgtttt
    52621 tttgataaat cttacaatta acatgattaa acctataata aataaaacaa taccagtaaa
    52681 accaaatata ccgtccatta atagatcctc tttctctttt gatattgaat attataaacc
    52741 aagcaattct tttttcttaa aatcgaattc ttcttgatta ataatccctt catctaacaa
    52801 ctctttatac tttttaattt catctgcact tgaaatttgt gtttctttgg aattattatc
    52861 taatatagat tgttgcttct ctatatattt ttttaaattt tccatttcat tccaatattt
    52921 ttttgtaaac ataacggtgt tttcatcttt cgtggccgct aatatacctc cgcgactttc
    52981 gtttccgcct agcaaggtaa attgtatata accattactc atacctggtt tttttaattg
    53041 tacggctgat atatttttaa aggggatagt tttttctcct ttaatacctt gattaactaa
    53101 atttataaat ccttttctaa taattgaaat agaatcatca gttactttaa tcaaggtttt
    53161 tcctggagat tttattaaaa tctctttttc cattttttct tcctcatttc tgtgatatga
    53221 ttttttttgt agaagctcat atatgaggaa agagcccgtg ttgcagcacg ggctttttta
    53281 atgttttgct gaaatcggtt tttttaataa ttcttgatgt attcatacat attgccttgc
    53341 gtaagaatat tttttcttaa aatagcattg gcagacagca taacaagtgt atctgagctt
    53401 attctgaata gaataatact ccataaattt ttcgagatta aactgagatt catcagtcag
    53461 ttcgttctca atatagatat ttaataaaat tagaatagct attttatctg cttctgtttc
    53521 aaattttgag tgaaaagttg tagaagtatc gtacaaaact gaaaattcaa aatgagaggc
    53581 gctgaaatgt gcaagttcat gagataaatg aaaggcttct gcagtttcac cgtatagatt
    53641 ttcattcaaa aaaatgattc tgggttttgg atagtagaaa ccaggctctt tcatctccat
    53701 ataaactact ttcaaattgt attcgctcaa catttctttc aatttcaaat acatacaaac
    53761 catcactcca actattcatt ttcctctaaa gctttagcaa ttgcaatcgc tttacgcatt
    53821 gtctccttag atatttcttt tccatcaaaa gaaaaaacag tatcgtcttc tgataaatcc
    53881 acatgtttag gggtttctct ttcttctcta cctagaaggt agtctacaga gacatcgaaa
    53941 tagtcagcaa tccgacttaa ttcatctgaa ttaggagtat tatttttcca ctttgctaga
    54001 taaccgttag aatatccaaa attaatttct aactgccgta tagatatctt tttcctcttc
    54061 gccaagtctt ttattatttc ataggtattc atcgataaaa caacctttct aaatgtttac
    54121 aaaaaaagtt tagaaaaata cgcagaaata atttgactaa ttctgagtaa tgagctatac
    54181 tatatcttgt aaacagattt aacaactaaa aagacaacaa aaaacactat tgatatgtaa
    54241 atgcagaccg ccaagaaagc tttaaaatca atgtttttat gtcttattta attatgctct
    54301 tagtatagag tattactcag atactgtcaa ttgaatttag aaaaaagttg ttaaatttgt
    54361 ttacgaatat aaaagaaagg aatgagaaat atgaacacac cgcaaatttt taatttcgaa
    54421 caaaacgaag ttcggacaat tttagtaaat gatgaaccat attttgtagg caaagacgtt
    54481 gcgagtgttt tgggttattc aaacactaaa gatgctttgt cgcggcatgt agatttggaa
    54541 gataagatgg ggtcgcgaat cacgacctca ggtcaatcaa gagagatgac aatcatcaac
    54601 gaatctggtt tgtacagttt aatcttaaaa tcaaaacttc cctctgccaa aaaatttaaa
    54661 cgttgggtaa caagtgaagt gttgccagca attagaaaac atggaggtta tctaactcca
    54721 gaaaaagtag aagaagcttt gcttaatcca gatacaatca ttcaattagc aactcaacta
    54781 aaagaagaaa gaactggaag attaatcgca gaacaaaaga ttgcagagta cgaacctaaa
    54841 atctcctatt tagatagcat attatcttct acagattcag taacaattag tcagattgca
    54901 gcagattatg ggatgtctcc acaacagatg aataaattac ttcataaact aggtattcag
    54961 aaaaaagtcg gtaaccaatg gttattgtgc aaaaaacaca tgaaccaagg atacacaaaa
    55021 tctcatacaa ctgagatccc gaaagccgat ggtggcacta aaattgtaat gaataccaaa
    55081 tggacacaga aagggcgtct atttatctac gaattactaa aaaaagaagg atattaccct
    55141 caaatggatt tagaggaaat tggttagaaa ggagttttag tatgactgac attgcagaaa
    55201 tcactcaacg agatagagaa aaaatcaaag aatatgtcga aagttcaaag ttcttaactt
    55261 acaccatgct tgctgaaaga tttggaatta gcaaaagcta cttatcttta attttaaacg
    55321 gtaaaaagac ttctgcagaa gcaaacagaa ttatagattc gattatcact atgtacgaat
    55381 tgtaaaggga ggaacagcta atgcaatatc tagaagcaaa aatcccaatt ccagaaggct
    55441 atgtaattat ctcccaagtg gattatgagg agttaaaaaa agctgatgat actggtagat
    55501 ggatgacgtt gccagaagtg ctagaacgga ttaacagaaa atatgattgg tttacttcta
    55561 gagttttaaa gaacccaaga tatagaaata ttatcgatat cgagaaaaac aaaaatggat
    55621 ttgtctatta tccagttgaa ggaagagaca catatctatt tttaagaagt aaaacacttg
    55681 aatttttaga aacaaatttt tcggaaatct taaggaggca agcggatggg aaaatttaat
    55741 agagcgctag tgttcagcgc accgctaatc atctacgctt taggactttg gggaagcagg
    55801 caagcgttga taggaacgat tgtttacatg gtttggattt ttatggggct tgatgaagct
    55861 gaagctgagt acagagcgaa aaagccaacc gagggggctg actaaaaatg aatagaaaag
    55921 agaaactaga atgtatatta ctattactca gtttaattct ttcactaatt tctctattgg
    55981 gaagtttgta tttttgatat caacaatttt gtggatttgg gttctattta gagtaaatat
    56041 catttttgtt tggtgattaa ggagtttatt aaaattaatt ttccctactt caaatgcaag
    56101 gtaacaagat atagcacttt taggaggaat atttagcggt acagcttcag agtatattct
    56161 attatcatcg actgatcctc ctttagcaat taatttctta aatggagtag ctgaccatct
    56221 gcggtttaag ttagcggatg aaagttctaa attaactaac atagctggtt ctgttgaata
    56281 gttagaaatg attacttttg tataaatcat atctgcagcg aagtaagaag cattaagttc
    56341 aacttctagt tgagggcgca ttccttttat ttttatccct gttaaaaacg tactcaatat
    56401 aaaacttatt attgacatcc attgaaaaat tgttaagtga aaaaaattca aaataaacac
    56461 caccagtttt taactaaatt ataccaaaaa ggagagaaga aataatgcaa gaattagtaa
    56521 ttttgaaaaa taaagaagct gtgactacga gcttacaagt ggcagaaagc ttcgagaaaa
    56581 aacatcaaca tgttttaaga gatattgatg cactaaaaaa agatgtgtcc aattttggac
    56641 agatgtttgt agaaggtaat gaaccagatt catatggcag aaatcgacga gttttcttca
    56701 ttagtagaga tggatttttc ttgctggcta tggggtttac aggaaagaaa gctatctact
    56761 tcaaacaaaa atacattgaa gcattcaacg aaatggaaga tgttattcgc aagaatactg
    56821 ttcctcaaac aattgaagat atgatgatct atcaattaga agaaatgaaa gatgttaaaa
    56881 aagatgtttc catgcttaaa gatactatgc gaattagcgg acaacaagag tttgaaatta
    56941 agcaaaaagg aaatatgaaa gttatgggag ttctaggggg aaaagaaagc cgagcttatg
    57001 aagaaatcag caaaaaagta ttctcaaaat tttggtctga atttaaacgt accttttcaa
    57061 tcccaagata tggcgagtta cctcgtaaga gattcgatga tgctgtttca tttattgaaa
    57121 tgtggttgcc agaaactgcg atccgtatgg aaattgatca actgaacaga caacagagac
    57181 tttttggtga tgacaatgaa tagagctgaa gcgctaagaa tagggacggc aattgctaat
    57241 tgctggtgga aatactataa accaatcatc ctaagccaac aacatattga caagcaaaaa
    57301 gcatggcaac aaataaaaaa gtgactccgc cggcaagcaa agagtcacaa agaaaacaca
    57361 tcataaggag attttagcat atggaaaaag aactttccac tctagatcaa tatttgattg
    57421 atcctgattg gggcaagccg aaaattgagg aaacaagtgg tcgaaaaatc agacgaaatc
    57481 ttttgacgaa tgaagaacta gcttgggatc aagatgattt aggcaaccat gtaactattt
    57541 gggatcatgt ttatcttatc catctatcga agcattcgaa taaacctgaa tatatttacg
    57601 tcatcgaaga tggcttgatt gatgcgctag aagagtacga cagagataac ttgattgata
    57661 tctcttatta cggaccaggt aagaaataca ttgctgaaat ggaggcagaa tttgatgagt
    57721 gaaatcaaag ggacaacgaa ctttgaaaaa ctttttagtc gtaagttaaa taaaattctc
    57781 aagaaaaaag gaaattttga ttatttatct tgggctcacg cgtgggagat tatgaaaaag
    57841 aatgatccac aggcaacggt aactattaat gagtacaaac actacagggt tgtttctgga
    57901 actcatcaag actttcttgt tgaggaatat aaaccttttc ttatggatga aactgggact
    57961 tatgtatctg tctcagtaac ggttaaagga cacacggaaa ccgaattatt tcctgtttta
    58021 gattatcgaa accaaccagt tgttaaacca aatgcaatgc aaatcaataa ctcattgaag
    58081 cgatgctttg tgaaagcatt ggctctacac ggactgggat tatatgtatt tcaaggggaa
    58141 gatattccaa caccacctag aatcgataca aagaaattaa acatgctaga gacgattcta
    58201 gaagctttca atgagcagat gggtaaagat atgaccaaaa ccttaatcga atatgttaat
    58261 gagcagacag ataaattagg gctcttagct gataacgttg aaactattga acagttaagc
    58321 tatgagcaat gtgccttgat ggagcgagca atagcagcta agagaaaaga attagataag
    58381 aagtgatatg agtgtttaaa ccattaatcg attcatattc agcggttctg aaaaagttca
    58441 aaggaaaaga cataagcgca accatcaatg aggaagtgaa cattgatcga ctaaagacga
    58501 tgtatgacgg ctacgatggt gatcgagtca ttgaaattcg ttttattgat cctagacgtt
    58561 tcaccgtaca gcaacgaaac ttcatctatg cgctgatagg cgatattttt atcgatacag
    58621 gcatgccaac ggacttctgg aaggaattct tctactttcg ttttgaaggt gtcacagggc
    58681 gcaaaataag cctgaaagac gaatcgaata caactgtgag tgatgccaat gtcttagcaa
    58741 atatcatctt agatttcatc tttgaacatc atattccttt caaagaaggc tatgagattt
    58801 tacctgcgaa tcaagaatat tacttctaca aatgcatcac aaaaagagtc tgctgcatct
    58861 gtggcaaaac aggagctgac atcgatcact ttgacaaagc gctaggaaga cgaaagcgca
    58921 aagaagttga tcatgcagag tacacatttg cagcactctg cagaatccat cacacagaga
    58981 agcacaaaat aggtgtgatt aatttcaaaa ataaatatca aatcaaaggg atcaaattaa
    59041 accagaaaac aatcaaaaag ttaaatattg gagggtaaaa atgacagaac atcgaagtta
    59101 ttatgcgatt ataccagcca acgtaaggta cgacaaaaga cttaaaccaa atactaagtt
    59161 gttatacgga gagataacgg ccttgtgtaa tgaaagaggc ttttgttggg caggcaatga
    59221 gtactttgca gatttatatg gtgtgaataa agagaccata tcgcgatggg taagtgattt
    59281 gattaagttt ggatacttga atcgggaaat catttacaaa gagggtacca atcaaataat
    59341 caataggtac ctacgaatta atcaataccc tattgacgaa aaacgcaata cccctattga
    59401 cgaaaaagtc aaagataata atacatctat taataataca tttaataata caaaagaata
    59461 tataagagag ttaccgcctt cgaaaaaatc gaaggctaag cccgtccgtc ataaatacgg
    59521 agagtataaa aatgttcttt tgtcagatga gcagatggag aaactcaaaa cagaattccc
    59581 taatgattac caagagcgaa tcgaacgact gtcagagtat tgtgaatcat ctggtaagac
    59641 ttataaaaac tatttggcaa ctattcgaag ttgggcaagg aaagaaaaaa gtgaacctaa
    59701 gaacgcaagc agtggataca agcgcacagg aagacgagag aagcttcctg aatgggcaat
    59761 cgaccaagaa gcctatctca agaaaaaagc gctagaacga gctaatagac aatcaaaagc
    59821 accattctaa gaggtggaaa aatgaagatc gattatctag aactaattaa tgaaatagcg
    59881 aattataaaa agggcgagga attagacgtc ctgagagacg tatatgatca actcgaagaa
    59941 gctggaattg aaggaattaa gaatgatcgt tcgagttgga gtaaactcag atactatttc
    60001 gcactctata tcgatggaac gcaattaaga aatttagcat ataccaaatt actattcatt
    60061 gattgtgtta aaggcttgca aaaacatctt aatgaacttg agcaggtgta aacaagatgg
    60121 acctaaagac atttacagca cagatcgaat taatgcatca agaagcttta agacaaagtg
    60181 tgtcgtacga agacaagtgg ctcaacacat ttcatggcgg acgtgagagc gcacttgatc
    60241 aagtactcaa attactgaaa ggagaatgtc gggatggata agaaagcggc aatgcagcga
    60301 attatcgaat tgacttattc agaagattgg caggaagata aaaaaatagt tgcagaagtc
    60361 caaaagctcg gtaaatcaat gtggactgaa aagcccaaac ggagaacgcc gagaaagatt
    60421 gcaatctggc atggtgatcg aattctagta acgggtaccg ctaaacagtt atctgaaatt
    60481 actggtctga gcaaaaatat tatttgggat agagctagga gcttatggat tgattcaaaa
    60541 ggaagacagt ttaggtatgt ggaggagaaa taatggacga actaatcgcg aaagtagagc
    60601 agtgggcaaa agataaggga ttggatcaag cggatttcag caagcaaatg ttaaaaacgg
    60661 tcgaagaaat cggggaagtt gccgcttctc tagctagaaa agatgaacat ggtttaagag
    60721 acggaattgg cgatgtagta gtaaccttga tcatcttggc aatgcaaaat gatatggatt
    60781 tatacgagtg cttggatttt gcttatgacg aaatcaaagg tcggactgga aagatggtca
    60841 atggtgtttt cgttaagtcc agtgacctga aataattcca ttaatggaag aaataactga
    60901 ataggaggat agacatgatt gatgcaaaac aagtgcaaaa acagaaagat ggaatgttga
    60961 tgtttgaagc atatgttcta ccatttctta atcaatttga agttttggaa tgctctgcca
    61021 gcggagaaga attggagtat gttgtaattc gtgaaaccaa agaaaacgtt cagaagctaa
    61081 acgaatttct ttgcactatt aactgttggg atatgatagc tccaggattt ttatgtccag
    61141 ctatgggaga atttttggaa tattgtcgtc ttgaagatgc aggcactttg gatttagctt
    61201 atctggtata caactaccta aacatcaaca cagatcattt gtggtttggc actgccgaaa
    61261 gaaaatgggt agtccgctaa ccaccaatat caatgaaaaa aggcggtttc ctgaaagtgg
    61321 aattgccgcc attgctgtaa ggttctttac gcgactcaag gtcacagaaa tataaatgca
    61381 aatctctttt gaagtgatcc aaagctctcg gaaaatggaa gttttttgtt tcaaagaata
    61441 aatgagattt gcgtcaagaa cctgagagtt atttccaaaa aagcttccaa agaaccgaat
    61501 gagctaagga catcatgtgt aaacacataa tatagctctc ctttcacggc taatcataac
    61561 atgaaaaata ttcgatgtca gtaggaaaaa aggtgaatta tgaaaagaat attaaattat
    61621 cccggcagta acagattctg caattaaact ccgaagctga tgtatcagta tcaactgtag
    61681 aatattatga gcgtggagaa agtcaagcag tcacaaatgt aaaaatcgat aacgtcaacg
    61741 gtcttatctg tttagatgaa ggcgatagta tgaatgaaat tgctgcagac catgaattat
    61801 cagaaactgc tttaattgat caaatcgaat tagctagaca atactttgtt ccatatgcag
    61861 atacctggtc caagcataag aatgacatca tttttccaga ggaacaatga gagcaactga
    61921 tccagtaatt atccttgagg aagccaaatt tatttggact cacgaagaga tagagcaagc
    61981 acgcttgctc ttttctcaag gagttaagcc gagcaaagta gctgaaataa tgggtcaaaa
    62041 gattcttgat gtcggattgc ttttgctcca tctagcagaa aaaaatttga tttgaggtga
    62101 aaatgatgat tcaacttgca ggcatccaaa cagggaaaat ttatttttct ggagaaagca
    62161 aaagcgaagc caaccaatgg ctattgaaaa cttacacgaa caataagaag ctaaggaaaa
    62221 aatatcctga tttgttgcta aaggatgatc agattatgcc ggaaccgatg attttgaccc
    62281 gtaaggaggg aagttgaaac taaaaaacca gccgtgtggg ctggagttgc tatttctttt
    62341 taataatgag tttttctaaa tttaattcat tctcacgagt ttgcgtccaa taatcagaat
    62401 aatattttaa ttgtttaaga gtaggaatgt cgtcttcggt aaaattagaa aataattctg
    62461 gagaattatc tttttttaat tgttctaatc ctgattcttt aaaacgttgt tcaacgagtt
    62521 ttactaaatt gttgatattc atgataaatc acctttttaa atttaatttc gatttgatta
    62581 atcgatacaa gtattatatc aaataaaaaa gctgatttag ggggtcttac aaaaacacta
    62641 aaattttttc aaaaagagga ggaacggtgg tgaaagtcag agaacaattc aagatagtga
    62701 gcgacgaaga taatgtttac aaaataaaga tcgttaatat taatgaatat cgagaagcag
    62761 atcacaaata tttggttgac ttatacatga acgataaata tttgggagaa ggattttgtg
    62821 gagattcact ttttgatgat gagcgaattt tgaaggagga aacagaatga tccacgaact
    62881 aaaaatacta ccagaatatt ttgaagcagt gacgagcgga cgcaaacaat tcgagatccg
    62941 caagaatgat cgtgacttca aagttggtga tcagttaata ctacgtgaat ataaaaaata
    63001 cattaaacat gaattacctg gactaacgag accaacattt agttacactg gtgactcata
    63061 caaagcagag atcacttata ttactgatta catgcagaag tccggatatg tagtgttggg
    63121 gattaaaggg gtgaattaaa tgaaagtata catcttagct atcacagagg gcacatggat
    63181 gttcccagtc ggttccggaa aaatctataa atcaaaaaca gctgcttata aagcatttga
    63241 aaaatacaaa aaagaaaacg gtggcggcac taacgcaaag attctagtgg ctgataactg
    63301 gcatgaagaa ggtgaacgta attgatttac ctgttcattt tcgtggtact aactattttt
    63361 atgctagtaa tcttattcaa aaaaagatga gtaaagacga acgaaaaatt ctggccaact
    63421 tttatttagt attaaaaatc gaacaaaatg tgttttcgga aaggagaatt gtatgggaaa
    63481 aacaaaatca aagattaaga agaaaaaacg acgtttggaa caaaaggcaa tccagaatgg
    63541 aacggctaag aaaaaataaa aaagctaccc ctttcgagat agcagcgcaa tactattcta
    63601 ccataagggg tggcgtttgt gagatttcat tggttaaaag attaccaaga actagatgag
    63661 cagattcttt acttaaagtg gaatcttaat aaaagtaagc ttgaattgaa tcgatgggtc
    63721 tgtggtgatt tagcaaacgt ccgcatcgaa aagaattcga gaacttcttc tttagaagag
    63781 aatatccaaa agatagaaaa tgaattggaa ttgttgatcg agcaaaaaga agaaatgtta
    63841 ttgctgatag atagcttttc tggtatcgat aatcaaattg ttaagatgaa atatgttgat
    63901 caaatgagct tagaagatat tgctgaatct gttgggtata gctcatcgta tgtcagacag
    63961 cgacatgcag aaattagaaa gacattgaac tttttagatg agtatgaaca cagacaagct
    64021 gaccgattga aaaaagaaaa cgaaattgat ttttacaata gcgagaagta caaagaacaa
    64081 ctctctttat tctaaaatta cactgttcac taaatgttcg gtcattgtag ctatgtaaac
    64141 attgttagca gcatgatatt ctattagtgt caaaaaaata tgaaagagcc aagatatccc
    64201 aaccgtttta ttaattggta tctgtggctc ttttattctt ttaattagta gttggcataa
    64261 agttatttcc atttataaat tgatcagcta aatcagcatc ataatcagcc gcgataaatt
    64321 gcgctgctga tttaataaat gcatccatat catgaacatc tttattagta tgtctacgaa
    64381 catagtgcgt ttcatcatta ccaatccaag tagcagcttt ggctaatctt tggagtttag
    64441 gaaaatcatt caaataattt tcaattgttt tacctaataa catttttttt attttatctt
    64501 catcctctga atttttagat attgcataat ctttaattag aaattctaga gcttttctat
    64561 aaccaactcc agcaatttgt tccaattgct cagatttagc ttgtgtggct tgagtataaa
    64621 tatcaacaaa tgtaggagaa actttttcaa tattttctgg taaatctatt ttaatcggcg
    64681 gacggtaata atctttaatt aaaatatttt cagaatatcc ttcatcttca ttaaacgtat
    64741 ttataaattg taaactataa aatttgttgc actcatcatt tatacactgt actaatacgc
    64801 caaagattct atcattatcg aacgcactat atgatgaaac cccaaaatac acatacggag
    64861 tcattatatt tccgcaatgc ggacaactat ttggcaaata aattgtctct gtattttgac
    64921 gatcacgata cttaatatta acttcttgaa gcattaaaac acctcgcatc ttttttataa
    64981 atcataccac aaaatatctg ataggagagt aaacaaatga atgattttca tgaagcggta
    65041 cttagtattg aagtagaatc aagtttggct aaagtttata agaaagcaat tgaagcagag
    65101 aatagtccgt acagagaaaa ttggaatggt aatcatgcac atgtgcaagt ggagaatgat
    65161 gattacagaa ctggaatgaa tacgttagtt atttctttat tgtcacacac tctacccaat
    65221 ctgcaggaaa cgattgaatg gtatgagcga atgggcgcaa aagtaatccg tacaaattac
    65281 aaaggagaga attaaaatgg caatgatcaa aattagaaca tccattagtg gaacagagta
    65341 ttgggattca gaaaagaaaa ggacagtagt tgttccgaaa gatcaagaac caaattttga
    65401 agtaaaagaa gaaaaaggaa ttttgagtga tggcaaatca tttgttgctg tcaatggcga
    65461 actcatagct catagcagtg aaattcttga tagcgatgga aacactgctg ctaattttga
    65521 tggagacgaa gctactaatg atcagtccac tgaagatacg gatgaactgg acaatatgac
    65581 tgcaaaagaa ttgcgtgcat atgctaagaa acatggtatt gatattcctg gtgctatccg
    65641 tgcaaaaggc gatatcataa atcttattcg tgaagtagaa tgaaatactg tcagtttgac
    65701 ggatgcacga acaaaatagc aaagggtatc tactgtactg aacacaagag atcaagcaga
    65761 tcacgcaaga agaagcagca agcaaagtct gtttatcatc atgagaacaa accattctat
    65821 cgaacgcaag catggaaaga tatgcgtcaa tttatttatg aaagagaagg tggtcattgt
    65881 cagcggtgtg gtcagttcat atttggaaag agagcacacg tccatcacat tgtaccaatc
    65941 aaagacaacg aactgcttaa gcttgatcca aacaatctca tgctattatg ttcaaaatgt
    66001 catccaattg ttgaaaacga aacggaagac aaaaaagttt ttccttcgta tttcaattga
    66061 agccccccta ttcattttca aaattttttc gcgtggggag atagggtagc ggggagtcac
    66121 gcgcatcgtt aggtcaaatt tttcaaaaaa caaagggggg tgtatacaaa aatgacgact
    66181 aaagcgcaac gtaaagcgat tattgatgaa aaagtaagtg ctgaaaaagc tcgtatctta
    66241 gaaataatga atttgtctga tttgtacacc atcactcttg atccattaat cgaatcatac
    66301 ttggatattt ttgaaattta ccaacacaaa tatttattgt ggaaggaaaa aggatttccg
    66361 gagacgcaaa aattcacgaa taaatcagga gctactaatc aatcaaaaca tccattggca
    66421 caacaagtag aaacttgggc agataagaag atgaaagctc tagatttatt aggattaaca
    66481 aacaaagcaa aaactggtag actaattgct ggaggatcga ccgcaagaaa agatgaagaa
    66541 attacacgcc cagaagtaaa gccagtagat gaactagcag cgcacagaaa taaatggcgt
    66601 aagaaggcag gtgctgaaaa atgattgaac ctggtgtaaa ttatgctgat ttatttgcaa
    66661 aagaagtaag aaagaaacct aagaagtatc ctaagaccgt tcgtttagca atagatcgct
    66721 ggtatcagtg gaaaaaaaga aaagatattt ggtttgatgt agatcgcgcg aatgaaatga
    66781 tggattgggt agaatcattt attgttcaca caaaaggaga aatggtggga aaaccgtttc
    66841 ttttagaacc ctgggaaaaa tttatttatt cttggattta tggttgggtt aaagaaaatg
    66901 aaaaaggcca aattgtacgc gttactcgtg aggcttatgt ccagattcca aaaaagaatg
    66961 gtaaaacatt gattgctgtc ggttcattag gatatgcaat gtacggagaa ggggcgttat
    67021 cagttgattg ctatgcttgc gcatctgatt ttgctcaagc gcaatatgct gccaaacctt
    67081 ttgcagttac aatcttaaac aatccaatcc tacttgaagg aactaaaata tttagggggc
    67141 caaagggaac tgtttctagt attacttatg actatattca tgaagatatg gcttactcaa
    67201 ataaatttat tgttcaaacc aagaatattg ataatatcga gggatccaat ccatattttg
    67261 tattgaacga tgaattgcat aaacaggaga aaatggaaca gtatgacaat tttaagtctg
    67321 ctcagatatc tttaccacag ccattgatgt ttaatatctc aactgctggg aaaggttcgt
    67381 cgtctgttgg aatgcgtgta tatcgcgaag caaaagaagt gttgaaacgt gatgataatg
    67441 attcaaactt tgttctaatc tatgagccaa ataaaaatta tgattggacg gatagaaaag
    67501 tctgggaaat gtgcaatcct aactggggaa tatcagtcga tttatctgct ttagaatcgg
    67561 catttaaaac agcgcaacgg tcagctcatt ccaaagctga atttctaacg aaacacttgg
    67621 atgtatttgt gaacggcgcg gataatttct ttgaacagga tcaagtagag ccatgtttag
    67681 ttaccacaca agaacttggt gatttaagtg gcgaaccatg ttatatcggt ttagatttat
    67741 cacgtacacg agatttgacc tgtgtatctt taaacttccc aacatgggat gaagatggta
    67801 aagcggttct taaagtaaag caactttatt ttattccgaa tgaagattta gagtttcgag
    67861 aaaaagaaga taatgttcct tacagtgatt tggctgaaca aggtttcgtt gaattttgcg
    67921 acggaaaaat gattgatcaa gatcagattt tgcagtacat agaggactgc atgaatttat
    67981 atgatattca gcaagtgaat tatgatccag cgatgagtga caaacttgtt gagaaattag
    68041 aaaacttagg attggaatgc gttgaagttg ctcaatatcc taaagtattg aatgctcctt
    68101 ttgacgatgt cgaacggttg ttttatgaga aacgaattca atttgataat ccattattcc
    68161 tttattgcac tttgaacgtt gtagcaatta ctaacatcaa tggacaaaaa gcgccaagta
    68221 aacgtcaatc aaagaaaaag attgatgggt tcgtggcgtt tttgtgtggt cataaggaaa
    68281 cgatgaatca aatgacagat attgattcag atgagttaga tgattaccta agttccatct
    68341 atagataaat agaaaggcgg tgaaaaaaat tgaaattacg tgatcggtta tcgaatgcag
    68401 tctattcttt tatggaaaaa cgtggatata tcgaggatat ttttggacac tacacacgtt
    68461 atggtcaaag atatgtgacg gattcatcta tcatggaatc ttctgatgtt tatgaattag
    68521 ttcaagacat atctaatcag gtggcattgg ccacaccaat tgttattggt cccgacggca
    68581 acgaagtcaa agatcatcac ttactaaata ttttgaagag tcccaatgat tatttgacag
    68641 gattcgaatt taccaaattg gaaacaaata ctttattgat caatggtgag acattcccat
    68701 taacggatag ggatcagctt catttggcgt acggtgtaac aactaaaatc aatgaacgac
    68761 ttcaagaaga atttgaaatg aatggtcaaa aaatacctgg tcaaatgatt cgacacatta
    68821 agaacatcgg aactgattca ttaaaaggtg ctggaataat tgatcttgca agaaacactc
    68881 tagaaggcgt tctgagcgct gaaaaagttt tgacggacaa atatactaaa ggcggtttac
    68941 ttgcgttcat gcttaaacta gacgcccaca tcaatccaaa taatagcgcc caaacaaaaa
    69001 ttgtcaaagc tatattggat caactggaag gaacgcaaaa tgagagtgat cattctgtta
    69061 agatgattcc tttgggaaaa ggatattcca tcgagacatt aaaaagtcct gttgatgacg
    69121 cggcaatttt gaattattta ggtgtttaca aaaaagactt aggaaaattt ctaggaatca
    69181 atgttgatac gtatcaatcg ctgatgaaga cagatattga aaaagcgatg atgtatctgc
    69241 acaacaaagc aatcaaacca atattgaaaa acaagagcga acattacacc gctctttttt
    69301 ttatgcctaa ttctggctat agagtggaat ggaaaattaa tattttggat tttgttcctt
    69361 actcaacaaa aacaaatatt ggctacaaca tcgttcgtac cgggattaca agtccagata
    69421 acgtggcaga aatgcttggt tttcctaaac agaatactcc agaaacacaa gctatctata
    69481 tttcaaatga cttatctagg attggccaga aaaatgcaac agatgattcc ttaccaacga
    69541 atgatcaaga cttgaaagga ggtgatggaa atgaagaaga aggaaattcg cacgattgac
    69601 atcaccaatc tttcaacacg ttccgatgaa gaaactcata cgaggaccat tagcggctac
    69661 gctgctgtat tcaacagtca aacactttta tgggatgact taagcgaagt gattgttcct
    69721 ggtgcattct caaaggcaat tagtaattcg gatgttcgtt gtttgttcaa tcacgattgg
    69781 tccaatgtgc taggacgtac taaaagcgga acccttcgcc ttgaagaaga tgaacgtggt
    69841 ttgaaattcg aagttgattt accggacaca acggtagcaa gggacttagt taaatctatg
    69901 gaacgaggag acatcaacca atgtagtttt ggttttgtgc cgactgaaga aacgtgggac
    69961 tacaattctg aaccaatgct tcgaacaatc catgaagtgg aattatacga ggtttctatt
    70021 gtgcctttgc cagcatacga agatacagaa gctgcattaa gaagtcgtga tgaattagaa
    70081 aaaaacgtcg aagaaagaaa aaaattaatc aaaaaaatta atcaagcgct agaagcgtag
    70141 gaggaaaaat acatggataa agaattattg aaaaaaatga aggcacgtcg tgagcaacga
    70201 ttgactgaat tacgtgaaaa agttgaatca ggagaattac gcgaagcaga tttagaagcc
    70261 gtgaaagaag aaattgacag tgttattgat gaattgaacg gaattaaaga cgaattaggc
    70321 gcagattctg gaactgatga aacagacgac aatacagatg atcaatcgaa tagtacggat
    70381 tcagacgaaa gccgttctgg tgaagacaac gatcaagaag aagattcaga cagtgaagat
    70441 agttcagaaa atcgttctgg aatgattact caacagcaac gagatggatt acttggatca
    70501 attaagaacg gattggaggc acgtgcaaaa atgaccaaga aacaaaaaga tcaacaacta
    70561 cgaaaagcat ttgctaattt tgtagctgga aatatttctg aagcagaagc tcgagcttta
    70621 gggattgaag ctggcaacgg ttcagttact gtcccagaag taattgcatc tgaagttatt
    70681 acttatgctc aagaagaaaa tttacttcgt aaatacggaa cagtggtgcg aacatcagga
    70741 gatgtcaaat atccaattct tgtgaagaaa gcagatgcga atgtaaacaa gaaagagcgt
    70801 tcaactgata ttgctgaaac agctattcag tttgatgaaa ttttgcttaa tcctgccgaa
    70861 ttcgatgctt tggcaacagt aactaaaaaa ttattaaaaa tgtctggtgt tccagttgaa
    70921 gatattgttg tggaagaatt gaaaaaagct tatgtgcgta aagaaatcaa ttatatgttc
    70981 aatggtgatg acgctggaaa tgaaaatcct ggtgcattag ccaaaaaggc tgtagcattt
    71041 aaaaaacctt tagatctaac tgcttcaggt gctgggcaaa aattatatga tgcattaatc
    71101 gaatttaaaa atacaccagt gacagaagtg atgaaaaagg gacgctttat tattaatcga
    71161 gctgctttga ctgccattga aaaaatgaaa acagatgatg gatttccttt gttgcggcca
    71221 ttcacacaag cagaaggtgg aattggttac caattagttg gctatcctgt ggattggaca
    71281 gatgcagcag ataaaaaggg tgaaccagac acgccagttt tatattttgg cgatttttct
    71341 gcatttaaaa ttcaagaagt tattggtgcc ttggaaattc aaaaacttgt tgaaaaattc
    71401 tctggtaaaa atcaaattgg attccaaatt tacaacttgc tagatggtca attggtttat
    71461 tctccatttg aaccggcagt atatcgctac gaaattacaa aaccagttgg tggttaagat
    71521 ggaagagcaa actaaagaat tgtctttaga ggaaaaattc aaatcacata ttcattttga
    71581 agagggcatg gatgattctt tgctctcttt ttatttaaat atggcaaaag attatgtcaa
    71641 aacagcaact ggtggccaac aagaatatct tattttgatg gttgccggca ttgcctatga
    71701 atatagagtt tcagaggatg aactcgacaa agctatgaat gccatgacgc catttatcgt
    71761 gcaaggagcg attcaaaatg ccgaagagac agaccaataa tctcagatgg aaagccgaat
    71821 tgctagacat caaaacagga acagacggaa acgatcgtcc aactacaatt tacgaattta
    71881 agcgtctaat attctatgaa gaactcggtg tgacttctca agaaaaatat ttatcacagc
    71941 aagccaagac agacgttgtc agacgaatta aagtcagatg ggataaatcc atcacagaga
    72001 aattaagtgc gctcaaaatt gattctgtaa cgtataacat tactcgcatt tatacgaatc
    72061 ccgatgcaag agaaatggag ttgagtttag cttatgtcga ttagctttga tgaattgaaa
    72121 acagcgctga aatcaacaaa gttagcagtg ttcagagaca aagccagatt agggacgatg
    72181 tatccataca ttgtgtactc aaatgtgagt aacagcaaaa aaatggcatc cggtaaagtc
    72241 tataaaaaat taccttatta ccaagtctct ttttttacac ttggaacaga acaggattta
    72301 gttgttattg aacaagcgct gcaaaatgct ggcattccat attcagattt tacaggtata
    72361 caaggtgatg agaacgacga taccgtaacc aactattaca catatgtgag gtgtgtggaa
    72421 aatgccaagt aataagaatg gtttttctga aatatcggat tatttaggaa acctttcaaa
    72481 agttgatccg aaaaaattat cgttggaatc tttagaagaa gcagctaact tttatctaaa
    72541 gcagttgctt cctaatattc ctaagtcgct cttaaaaaag aaacatatgc gcgatcaaat
    72601 aaaagtagta gttgaaaacg atcaagtgaa agttcaattt gaagagacgg ccttttactg
    72661 gcgctttgcc gaaaatggca caacaaatca acgtgcccaa cattttgcaa gtggtacgta
    72721 tgaacaaaac aaagaaaaaa ttgaagaaat tatgactaga aaaatacttg atttatggga
    72781 agggtgattt taattgggaa aacaagatac tttttatttt gaaggattgg acgacatttt
    72841 aattgcgatg atggcaacgc cagattctgt tggaactgca ccgacttata gtgaagtttt
    72901 acgattgcca attgccacaa aaatcggtgt caaagggaat ggaacagcat tagaaaaatg
    72961 ggcatccagc aaaatgtttc gtcgtgtgtc gcgagaaaca aaacatgaac ttgcgttgga
    73021 tcacgtgggt attccgatag aagtgatgga tgaaatcaaa ggattagttg ctaaaagcgg
    73081 agtaacgttt agcaaaaata ccgcacgaga atttccgtac ttcgcctttg gatttattgg
    73141 aaatattgaa aatggcggta aaaaagcagt ttggtatcct aatacacaac tatccaatgt
    73201 gattgacgaa gagtatgcca ctgcagagga agaaacaaaa attgacgatg taactgcaaa
    73261 tctggtttcc atcggactga aatacaataa tgtgatgtat gcaagttttg attcaaatag
    73321 agacggagct tctctagaat tatttaataa attcattgct caacctgtat acgatgaaga
    73381 acagtggaaa acattggcta aagttggagg tgcgggttaa tggctcggtt atctgattat
    73441 ggaattcacg ttgaagactt aaaaaattct gctgttgtaa ttattcaagg cgcagaattc
    73501 cctatttcat ttactatgca aacgatggaa tttatagcag atgtgtatgg tggagattat
    73561 tcgcaatttg aatctgatat gaacgccatg ctatctaaaa aagaaggaca aatttcttct
    73621 gctaacttat cgcctagtga tctaaaaatc atgcgtgcct tgatttatgc catgctgcgt
    73681 actggtggtt tagaggaaga tccagaaact attttcaaat ttttgggaat gagtggagag
    73741 gtgttgtctg cttatagtac ctgtatggaa atttttgcta gccagacatt tcaggtggaa
    73801 gacctaaaaa aatccaagaa gccacaagac tttcaaaaag cgcaagcaaa aagaaagaaa
    73861 aacaaaaaga atcggaagag ataggaactc cttggagttt ttatatttac gttgctctca
    73921 ctctattgaa ttggagtgag agtttctttt taaagtctac acctaacttg tggctcaaat
    73981 cttatttaca gtggttacaa caaaacaccg attttgaacc acctcaatct gtaactatgg
    74041 ataaatcgcc ttggtggtag aaaggagcgc taagataaat ggctggtaaa gaatctgatg
    74101 tcgttcttaa ttttaaaacg aatggcgaag tcagttattc gaaaacaatc aaagaaatca
    74161 acaaagaaat gaacttagcc gctgccgagt acaaaaacca agtgtctgcg atggacaagg
    74221 atgcaactca aacagaaaaa ttgcgagcgg ctaaacaaaa attagaaaaa caattaggat
    74281 tggctgaaca acgatctcaa atgctgagag aggaatatga aaaatctgtc aaagaaaccg
    74341 gtgaatattc tgctgaatca gaaaaacttt ataaacaatt actcaattct gaaaccggag
    74401 aaaataaact tcgtacagca ttagaacaga cgaacgatgc acttaaagaa caaggtgacg
    74461 tttctgttga tacagcaaaa aaactccaga aaatcgaaga aacaggtgag aaagtaaaag
    74521 gcgttggtga aaaaatgtct gttggagtaa ccgcgcctat tgtagcggca ggagcagcag
    74581 gacttgcagc atttggtgaa gttgacgagg cacttgatac catcattaca aaaaccggag
    74641 caacaggtga tcaagctgat agactttcac agtctttcaa aaacgttggt tcaaatactc
    74701 atttaccttt acaaacggtt ggggaagcta ttggtgaggt aaatacacaa tttggattca
    74761 tggataaaaa actggaagat tcaaccaatt atctcctaca gtacgctgaa atcaatgata
    74821 cagatgtttc gcaatcagca atatctgctc gacaagctat tgatgcttat ggactagaat
    74881 atgatgattt gaattctgtc cttgatgtaa caacgaaaac atcgcagaat actggtcaat
    74941 ctgtagacga cttgatgcaa aaagcaattg atggcgcacc acaaattaaa caattagggt
    75001 tgagctttgg tgaaggggtc actttacttg gacaatttga gcaatctggt gttgattcaa
    75061 gcgcagcttt aagtagttta tctaaagcaa cagtggctta tgcgaaagac ggaaaatctt
    75121 taagtcaagg actagaagaa ctacaagaca aggtaaaaaa tgcaggttct gaaacagaag
    75181 ccatcaatgc agcagcagaa gtattcggga ctaaaggcgg tcctagaatg gccgatgcaa
    75241 ttcgtagagg tactttgaac ctggaagatt tagcaaaaac tgctggagaa agtgggggag
    75301 ctgtaggaga cacattcgat gctactctcg acccaattga tcaagccgat caagctatga
    75361 acaatgcaaa attagcaatg gctgacgtag gtgaagcagt ccaagtaagc cttttgcctt
    75421 tttttgaaaa agcaacttcc ttattacagg aattctctaa atggtggggg tctctagatc
    75481 aagatacaaa gaattggatc ataacaattg ctggtatagc ggcagcagtt ggaccagtac
    75541 taatcgttct tggttcactt atgggatctg ttacaaaaat cgttggggaa gttaaaagtt
    75601 ttataggagt ttggcaagga cttgctggtt tatttggaat gtcgggaggc tggtttgcat
    75661 tagcagttat agctattggc gcattagtta ctggactaat ttgggcatat aataacgtta
    75721 aatggtttca tgatggagtg aattctttct tcaaaggtgt ttcagatgta gctgttgaaa
    75781 tatttaattt tttaagtggt tattttggtg gatttttcga tggtgttata gcaaatttca
    75841 ataattttta taatgctgga aaacgaattt tcagtggttt tctagatttt atcactggag
    75901 tatttacagg gaattggtca aaagcatggc aaggtctagt tgatattttt ggaggtattt
    75961 tcgatggtat tgttgctgta gggaaagctc ctattaatgc catgattgga ttgatcaatg
    76021 gatttattgg tggattgaat aatataaaga taccaaaatg ggttcctggt gtaggtggaa
    76081 aatcattttc tatttcaaaa ctgccttatt tagcacaagg cggtcatcta atcaatggac
    76141 aagcgattgt tggtgaagct ggacctgagt tactgactgc caagaatggt aaaaccacag
    76201 ttactccatt atcagacgaa gaaaaacgca aagggatcag tggaagagtt tctggaggta
    76261 gcattgaaca gcatatacac attggcaaag tcgatgcaaa caatccatct gagttagatc
    76321 gtatgaatcg taaatttgct aaagcaaaca aacaggctat tcgtgatttg ggaggtgttc
    76381 ctatttgagt cgacaattta tgaatccaga tgaaccaaat tttatttgga aaaatcggaa
    76441 tgcagtaatt gatatgaatt gcatcattga ggcagagctt ccagatatta tgccgaacaa
    76501 gcgatacgaa acttacacga ttcagggccg aagcggagaa ttgacggaga cgtttgatga
    76561 ctatgaacct tttgatttgg aaatagaagg gatcactatt ccacattcga aactgagaga
    76621 agtcaaacga tggctcactg gtaaaagcca attaatcaca cataatgatc cagacaagta
    76681 tctagaggct atctgcagca tggataaaga agtccctttc gaaaacgagt ggggcttctt
    76741 ttatacattc gatgttactt ttcgttgtca gccactcaaa agaaaaatcg gtgaagcacc
    76801 taaaattttt cattctagtg ttatggatat ttttgatcat ggtgacgaaa ttgcacatcc
    76861 ctatctggaa atagaatcga acggaggaga tataacgatc gctgtcggtg ataaaagcct
    76921 aacaatactt aatacgttag ctgcaacaat cgtggttgat actcagcttg gaaaagcaat
    76981 acaagaaggt ttgaatttat ttacgcgtgg tgattggcca gtattgcagc ctgaatggaa
    77041 tcaggtaaaa atatccggaa aatttaaaga agtgcggttt tggaatagga gtgtgtatct
    77101 gtgacgcaag aatttattta tgcttataaa aaaatgccag atgatttgag cgtgaacgga
    77161 gcgtcgttag ttgattggga agatttgcca gaaatcaatc gtgtgctgaa tggccaatat
    77221 cgtttttatg gtaactattc aagaagcgga cagtatcgct cttatttaaa aaaaggaaat
    77281 tttataaaag cgaaggtacc agatggatca tggcaatatt ttgaaattta taatgtcaaa
    77341 aagaatttga cctccgtttc tgtaacagct cggcatattg gttttatggc caataagaac
    77401 tttattgtca agtcgtttac ggataacggc aatgggtctc agatcatgac caatcttaaa
    77461 aacagtttgg catttgatca aaaatttaac tatctttcga atgtagggac aacgcaccaa
    77521 tttacagcaa gacaagtcgc gccagttgaa gcaatcattg gttcaaataa cggtaatcaa
    77581 aatttgactg gcgtgactag cgcggaactt gatatggata actatgattt gaaactggta
    77641 aaacagattg gatcagataa tggttttcgg attgattttg gcatcaattt agaagcaatc
    77701 gaagaagaaa ttgatgaaga atcaattgtc aatagtttgt atttggttgg cggtgttcct
    77761 gataacgatt atgatgaaga caaagaacct atcgaatatg gttatttaga aattgatgga
    77821 gtaaccaacg agaatcgacg tattgccaaa cgtgaaaacg gagattgtaa aacagttgat
    77881 gaattgatca aatggggcaa aaccttattt gacaatgatc gtatccatga gccaaaagct
    77941 actcatacag tcagtatggt ggcgttggaa cacacactcg aatacggtga catgtatcaa
    78001 gagctagcgt ctttacactt tggtgatgtc gctcatgtta gggcgaaaga gctagatatc
    78061 gagataaaag agcgtatggt cgaatacact tatttcccaa cgcttgggaa atataaggat
    78121 attgttttag gtaatgattt atcactgtac acttcggcag taaatactca agcacaagaa
    78181 ttgaaaaaga aaatcgacaa tcgaacagaa acgttagttc aaaatgtgtt gaatgcgacg
    78241 gcatggatca ctggtaattc tggtgggcat gtcgtttttc gtccagaaaa agctccatca
    78301 gagattctta tcatggatac tccaaatgtg gcgaatgcaa agcgagtgtg gcgttggaat
    78361 ttaaatggct taggttattc agacaacgga gtaaatggcc cgttcggtat tgctatcaca
    78421 tcaaaaggag aaattgttgc tgacttcatc aaagtaggaa caataaatgc agaagtattc
    78481 gaaacttcct ttaatgctta tggtgatgtg ttaaaacttg taaaaggcac gcttcaaatt
    78541 tggaatgaaa acaaaaaaat catggagcta accaaaaaag gtatggaatt ctggaataga
    78601 aaagaatcca ttggaacgat cggaacaaca gattcagcag gaaatccatt tccaaatgct
    78661 gtaacaccta cacctcttga ggaaaattct ttggtaatac gtacaaatgg cgatggaaaa
    78721 tacattttaa tttctccaac tgcagaaaaa ggatttgtgt tattaggaaa cggaaaagca
    78781 tattatttcg gtgatttaga tattcaggga aaacttactg ttagaggtaa agaagtgata
    78841 ccaggacaaa atggcggtcc atctggcgga ggagaaacac ctggtgggta tcctgatgaa
    78901 ttaaaaacag atgcagaaaa gagagcttgg agaatatacg atattttgtg taataacgga
    78961 tttacgaaac aatctgcatg tggaatattg gggaacattc aacaagaaac aggaggaact
    79021 tttgatcctg atactgttca aataggtgga ccagcatacg gattagttca gtgggatggt
    79081 tcttcatatc ctcttgttgg tccagcaaca tgggatggaa aagtttatgt tcaaaactta
    79141 tttaatgctg caggtattaa agaaccaata acgagcttag atgcacaagt tcgattgctt
    79201 atttggacat ttacaaatgg acaatggatg ggcgtagtac aacctacgac ggttgatgga
    79261 tttaaggcct gtactgatcc aagacaagca gcatatgctt ttgaacgaaa ctatgaacgt
    79321 ccggcagcga cacatcctga acgtcaagat tatgcagtta actggtataa caaatttaaa
    79381 gatttaaaac caggaggagc tactggagaa gcaggactaa aacatttaga gtctttgatt
    79441 ggacaacgaa ttggcaatgg tcagtgttat ggcttgtctg cagaatattc aggatatctg
    79501 ggtggttgtg gcatgggtgc tggaacaaaa tatggtttaa ctcatgtgat aggaaatact
    79561 tctgcagcat ctgatattgg tattgcctat gattggtctg ctgttggttg gaaagtgatt
    79621 caaaacccta gatatgatca attagtagtt ggtgcaatta ttaattgggc aagaggtgga
    79681 caagtgggtt catggtttgc agacggaact tatggacata ctggcgttat ccgaggctta
    79741 gctaatggtc gtatgcaaac ttatgaacaa aacacagagt taggtatgat ttgtggaaag
    79801 ttagatcgcc agtattatag tgcaagtgca atttcttcca ttgtcatacc accaaaatag
    79861 ggaggtgatt taatggcaaa gtggaatgtc atattaagta caacagaacc ctataattac
    79921 gtggggatga ttcaagttcg acaaggcaat aaaaacactg aagttatgga agctacaatt
    79981 gtcgaaaatg gtcttccata tgatttatca gaatgtaagg tatattttga atcagttgtt
    80041 ggcggaaaat atccagtcca attagaaaca agaattgtgg atgctaaaaa agggaaaatc
    80101 aa
//
LOCUS       DARPZJ010000008        74633 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.008, whole genome shotgun sequence.
ACCESSION   DARPZJ010000008 DARPZJ010000000
VERSION     DARPZJ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.008"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(3..2189)
                     /locus_tag="SLE23_000693"
     CDS             complement(3..2189)
                     /locus_tag="SLE23_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEI8467618.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            2407..3090
                     /locus_tag="SLE23_000694"
     CDS             2407..3090
                     /locus_tag="SLE23_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEI8467619.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(3171..3890)
                     /locus_tag="SLE23_000695"
     CDS             complement(3171..3890)
                     /locus_tag="SLE23_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEI8467620.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4202..4408)
                     /locus_tag="SLE23_000696"
     CDS             complement(4202..4408)
                     /locus_tag="SLE23_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467621.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            4653..5255
                     /locus_tag="SLE23_000697"
     CDS             4653..5255
                     /locus_tag="SLE23_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEI8467622.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            5396..6677
                     /locus_tag="SLE23_000698"
                     /pseudo
     CDS             5396..6677
                     /locus_tag="SLE23_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
     gene            6690..7418
                     /locus_tag="SLE23_000699"
     CDS             6690..7418
                     /locus_tag="SLE23_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8467623.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(7487..9010)
                     /locus_tag="SLE23_000700"
     CDS             complement(7487..9010)
                     /locus_tag="SLE23_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEI8467624.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            9262..10443
                     /locus_tag="SLE23_000701"
     CDS             9262..10443
                     /locus_tag="SLE23_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8467625.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(10503..12131)
                     /gene="treC"
                     /locus_tag="SLE23_000702"
     CDS             complement(10503..12131)
                     /gene="treC"
                     /locus_tag="SLE23_000702"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEI8467626.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12582..15293)
                     /locus_tag="SLE23_000703"
     CDS             complement(12582..15293)
                     /locus_tag="SLE23_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467627.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(15303..16004)
                     /locus_tag="SLE23_000704"
     CDS             complement(15303..16004)
                     /locus_tag="SLE23_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467628.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            16190..16789
                     /locus_tag="SLE23_000705"
     CDS             16190..16789
                     /locus_tag="SLE23_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8467629.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            16870..17883
                     /locus_tag="SLE23_000706"
     CDS             16870..17883
                     /locus_tag="SLE23_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEI8467630.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            17991..18908
                     /gene="rbsK"
                     /locus_tag="SLE23_000707"
     CDS             17991..18908
                     /gene="rbsK"
                     /locus_tag="SLE23_000707"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEI8467631.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            18936..19331
                     /gene="rbsD"
                     /locus_tag="SLE23_000708"
     CDS             18936..19331
                     /gene="rbsD"
                     /locus_tag="SLE23_000708"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEI8467632.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            19331..20704
                     /locus_tag="SLE23_000709"
     CDS             19331..20704
                     /locus_tag="SLE23_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8467633.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            21061..23205
                     /locus_tag="SLE23_000710"
     CDS             21061..23205
                     /locus_tag="SLE23_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEI8467634.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(23257..24297)
                     /locus_tag="SLE23_000711"
     CDS             complement(23257..24297)
                     /locus_tag="SLE23_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEI8467635.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24574..26376)
                     /locus_tag="SLE23_000712"
     CDS             complement(24574..26376)
                     /locus_tag="SLE23_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467636.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(26390..27142)
                     /locus_tag="SLE23_000713"
     CDS             complement(26390..27142)
                     /locus_tag="SLE23_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467637.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(27151..27513)
                     /locus_tag="SLE23_000714"
     CDS             complement(27151..27513)
                     /locus_tag="SLE23_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8467638.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(27689..28561)
                     /locus_tag="SLE23_000715"
     CDS             complement(27689..28561)
                     /locus_tag="SLE23_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEI8467639.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(28612..29100)
                     /locus_tag="SLE23_000716"
     CDS             complement(28612..29100)
                     /locus_tag="SLE23_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HEI8467640.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(29238..30029)
                     /locus_tag="SLE23_000717"
     CDS             complement(29238..30029)
                     /locus_tag="SLE23_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEI8467641.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(30084..30692)
                     /locus_tag="SLE23_000718"
     CDS             complement(30084..30692)
                     /locus_tag="SLE23_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEI8467642.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLVWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(30685..31002)
                     /locus_tag="SLE23_000719"
     CDS             complement(30685..31002)
                     /locus_tag="SLE23_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8467643.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(31158..31886)
                     /locus_tag="SLE23_000720"
     CDS             complement(31158..31886)
                     /locus_tag="SLE23_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HEI8467644.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFTLVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            32045..32926
                     /locus_tag="SLE23_000721"
     CDS             32045..32926
                     /locus_tag="SLE23_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8467645.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(33163..34206)
                     /locus_tag="SLE23_000722"
     CDS             complement(33163..34206)
                     /locus_tag="SLE23_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8467646.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(34209..34877)
                     /locus_tag="SLE23_000723"
     CDS             complement(34209..34877)
                     /locus_tag="SLE23_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8467647.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            35019..37355
                     /locus_tag="SLE23_000724"
     CDS             35019..37355
                     /locus_tag="SLE23_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8467648.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(37470..37781)
                     /locus_tag="SLE23_000725"
     CDS             complement(37470..37781)
                     /locus_tag="SLE23_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467649.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            37962..39437
                     /locus_tag="SLE23_000726"
     CDS             37962..39437
                     /locus_tag="SLE23_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HEI8467650.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            39484..40068
                     /locus_tag="SLE23_000727"
     CDS             39484..40068
                     /locus_tag="SLE23_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HEI8467651.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            40070..40489
                     /locus_tag="SLE23_000728"
     CDS             40070..40489
                     /locus_tag="SLE23_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HEI8467652.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(40770..41054)
                     /locus_tag="SLE23_000729"
     CDS             complement(40770..41054)
                     /locus_tag="SLE23_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HEI8467653.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(41406..42116)
                     /locus_tag="SLE23_000730"
     CDS             complement(41406..42116)
                     /locus_tag="SLE23_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HEI8467654.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(42113..43585)
                     /locus_tag="SLE23_000731"
     CDS             complement(42113..43585)
                     /locus_tag="SLE23_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEI8467655.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            43723..44196
                     /locus_tag="SLE23_000732"
     CDS             43723..44196
                     /locus_tag="SLE23_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8467656.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(44349..44900)
                     /locus_tag="SLE23_000733"
     CDS             complement(44349..44900)
                     /locus_tag="SLE23_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8467657.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            45005..45535
                     /locus_tag="SLE23_000734"
     CDS             45005..45535
                     /locus_tag="SLE23_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HEI8467658.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(46018..46461)
                     /locus_tag="SLE23_000735"
     CDS             complement(46018..46461)
                     /locus_tag="SLE23_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467659.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(46477..47637)
                     /locus_tag="SLE23_000736"
     CDS             complement(46477..47637)
                     /locus_tag="SLE23_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8467660.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            48144..49844
                     /locus_tag="SLE23_000737"
     CDS             48144..49844
                     /locus_tag="SLE23_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467661.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(49946..50779)
                     /locus_tag="SLE23_000738"
     CDS             complement(49946..50779)
                     /locus_tag="SLE23_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEI8467662.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(51083..53248)
                     /locus_tag="SLE23_000739"
     CDS             complement(51083..53248)
                     /locus_tag="SLE23_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8467663.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            53508..55802
                     /locus_tag="SLE23_000740"
     CDS             53508..55802
                     /locus_tag="SLE23_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEI8467664.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFKLLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            55795..56460
                     /gene="pgmB"
                     /locus_tag="SLE23_000741"
     CDS             55795..56460
                     /gene="pgmB"
                     /locus_tag="SLE23_000741"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEI8467665.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFTKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            56453..57460
                     /locus_tag="SLE23_000742"
     CDS             56453..57460
                     /locus_tag="SLE23_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEI8467666.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            57482..58501
                     /locus_tag="SLE23_000743"
     CDS             57482..58501
                     /locus_tag="SLE23_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8467667.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(58782..60150)
                     /gene="nhaC"
                     /locus_tag="SLE23_000744"
                     /pseudo
     CDS             complement(58782..60150)
                     /gene="nhaC"
                     /locus_tag="SLE23_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(60259..61680)
                     /locus_tag="SLE23_000745"
     CDS             complement(60259..61680)
                     /locus_tag="SLE23_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467668.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(61923..63800)
                     /gene="tdc"
                     /locus_tag="SLE23_000746"
     CDS             complement(61923..63800)
                     /gene="tdc"
                     /locus_tag="SLE23_000746"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEI8467669.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(64091..65347)
                     /locus_tag="SLE23_000747"
     CDS             complement(64091..65347)
                     /locus_tag="SLE23_000747"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEI8467670.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(65459..65664)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            65927..67228
                     /locus_tag="SLE23_000748"
     CDS             65927..67228
                     /locus_tag="SLE23_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEI8467671.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(67297..67896)
                     /locus_tag="SLE23_000749"
     CDS             complement(67297..67896)
                     /locus_tag="SLE23_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8467672.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            68150..69031
                     /locus_tag="SLE23_000750"
     CDS             68150..69031
                     /locus_tag="SLE23_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467673.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            69044..70654
                     /locus_tag="SLE23_000751"
     CDS             69044..70654
                     /locus_tag="SLE23_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HEI8467674.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(70731..71390)
                     /locus_tag="SLE23_000752"
     CDS             complement(70731..71390)
                     /locus_tag="SLE23_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEI8467675.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(71673..72338)
                     /locus_tag="SLE23_000753"
     CDS             complement(71673..72338)
                     /locus_tag="SLE23_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HEI8467676.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(72485..73090)
                     /gene="dhaL"
                     /locus_tag="SLE23_000754"
     CDS             complement(72485..73090)
                     /gene="dhaL"
                     /locus_tag="SLE23_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HEI8467677.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(73118..74128)
                     /gene="dhaK"
                     /locus_tag="SLE23_000755"
     CDS             complement(73118..74128)
                     /gene="dhaK"
                     /locus_tag="SLE23_000755"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HEI8467678.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(74103..74549)
                     /gene="dhaM"
                     /locus_tag="SLE23_000756"
     CDS             complement(74103..74549)
                     /gene="dhaM"
                     /locus_tag="SLE23_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEI8467679.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
BASE COUNT        22151 a        15175 c        13350 g        23957 t
ORIGIN      
        1 tatcactttc cttttttcac acgactcccg gtttctttga taaatctcga tactttcaat
       61 tttcttgaat ttttcatttg aggtacacat agatacagac gatttcttgc tctagtcatc
      121 gcaacataaa atagtcttcg ttcttcttct atcgtcgtta ctggttctgc ttttatttca
      181 ttaaagtcga ttactttctt ttctgtcgct ccgttataag gcaaacttcc ttcgttacaa
      241 ccaatcaaaa agacatttcg gtaactaaga cctttacttt tgtgaatgct ctggatacat
      301 agtgcatcaa gttttccttg tctgtaagca atcaagcggg tttttaattc tttagctgtc
      361 gcttgggttt cttgcgataa ggcttggagt cttctgaaag tagcatgctg ctttacttct
      421 tctcgtatcc attcttgatc actctggtcg atttccttag ctatacgtgg cagatgaaga
      481 tagctttgaa caagcgaata gatttcttga tgctggtctg ttttacgcaa cgcttcctca
      541 aactctcgga tttctgcaga tttcgatttt aaattggggc ttatcgacaa aatataatct
      601 gcaacggata tattttgata tttaggagaa aagtattgat cgcattcact ttttttcagg
      661 tagcagtctg ccatcagctg ccggagcaat tgctggtagg cctgattttt cttttgcaga
      721 ttcagtgctg tttgccaatg aacaattttt tgatagaaat gttggaaaga cttgatacca
      781 aagatacctt catatggact atctgcttcc agtacaaaag gaatattcgt tttcagcaga
      841 gattggacaa gctgctgcgt ttgtgaagct gatcggtata atatgattga ttccttatat
      901 ttcccatttt tttgaataaa tgtctgaatt tgtttgatta gccactgact ttctgcttta
      961 gtatcagaaa acaaataggc ttccataaca cctgcttctt tttgtgctgg aatcatcgcc
     1021 tttggtatcc gatcattttt attatagctg atcaatctat ttgctccttg gacaatagct
     1081 gcccgagaac gataattagt taataagaaa agagttttgg taggatattc tttttcaaag
     1141 ttcttgatgt atgctggctc tgatcctctg aatccataga tactctgatc atcatctcca
     1201 acaacaatca acttgatcct gttttccttt gtcatccgtt tcacgatttc ccattgaagt
     1261 ggattagtat cttgaaattc atcaatgaat agataatcat atttttggcc gatataatgc
     1321 tggatctcct cattctccaa agcgcttttc agattttgga gtacatcatt gaactctagc
     1381 aattgctggc ttcttttttg ttcttggagt tccgtgagca atccatacag tcgttctgat
     1441 atcggctgtc gtgcattctt atcaatggaa tcatattttt ctttaactaa ctgaaccatt
     1501 tcttctactg aaaggttcat attctgccaa tagtctaacc gagaagcaat cgttttttct
     1561 ccatattgat caaatatata aagattatat ttacgtatca gctgttgcaa aacagcattc
     1621 actttttgtg cagtatcctt tgaaaagtct ccttgtattc cttgcattgc tacttcagga
     1681 aattttcgac aaatttcatt gtatatccta aaaaagatac tatggaatgt tccgatatgg
     1741 acagcggttt ttctctggct gaaattatct actcgttttt ttagttcatt tgcagcgttc
     1801 cttgtaaaag tgatcattag tatgcgttct tcgtctactt gtttttgcgt catcagataa
     1861 acagcttttg cacagattgt ttgcgttttg ccgctcccag ctcctgctat gattcgaaga
     1921 tgtttcttca tatcatatgt gatagctgct ttttgttctt gattgaagcg attataggaa
     1981 cgtttctcca tcattttaaa gaaagagctg tttccttcac tttcttttac ttgtacttct
     2041 tcctcaataa gtccgggtgc ttcgccataa gccgcttcat aggtagcaat gatttcttct
     2101 tgtagccgaa agacttgttg aagcttttta tacttgttct cccagcgttt caattctttt
     2161 tgtaatcgga gaatttcttt ttcattcaac tgattgattt ccttcccatc tttcttcttt
     2221 gaatttgttt atttcaagtt ggttatttaa agtttcgttg tctatttttt ctttatacta
     2281 acagaccttt ctaaaaatga aaatgggaag cgatatgatt ttagttttct gaaaattttt
     2341 cctttttttc aatcgtttat gctaagataa ggaagacaaa aatattcata aaaggtgatg
     2401 aaaaaaatgc agacttcctt tcacgagggg cgtacaatag gacttttgct gacatttatc
     2461 ggaggagcca tggacagtta tacttatatc caatatggtg cttttgcctc tgctcaaact
     2521 ggcaatatca ttctatcgat catccaagca tttgacggag aatggctaag tgttggtaaa
     2581 aaagtattgt ctaccctttt ctttttctta gggattcttc taacaaagta tctaattgat
     2641 tattttagaa aaaaagaaaa acatttctgg cgcttgtttg ttctatatta tgaagcagtg
     2701 atttttttct ttgttagttt gacacccgtc catgagcatc ccgcattagt aacgattttg
     2761 attgctttta ctgcatcgat ccagtgggta gcttttgata aaatcaacgg gcgtgcctac
     2821 actaatttat ttacaactgg aaatttaaaa ggggtagcaa cgaacttata tgattattgt
     2881 atttctaaag aaaaagcaga ttttgatcga tttttccact atctaagtgt cgttcttgcc
     2941 tttatcgcag gagctattgt ccttgttttc tgtcatcatc tgtttggcgc ccattcgatt
     3001 ttgatcgttt ccattttatt tttgatcatg gccctcactc agacatttca tttatggcaa
     3061 ttttatcata cgaatcggtt cactatttga tctcaatgaa tcaaaaaaac taagcaagat
     3121 gctgctcaca gagaaatatc tgcgagtgag caatttgctt agtttttata ttatttagtt
     3181 gtaaagattc cctttgcttt cgggttattt gtagtgtagc ggatcgactg ggcatctgcc
     3241 tcttctgtca ttttctttgc ccgcatcttg atttcttgta cgatttgttc tccacatgcc
     3301 ggatcggcta cgaaatcata tttgtcccca tcgatcacta ttttgggaca tatatcaaac
     3361 tgttcatacc actcttcgta tcgtcgattg agttctttat agtaggaata gagttcagga
     3421 tcttgttcta gctgttcata ttcccggcct ctttttttga ttctcgctaa catagtttca
     3481 aaggatacac gaatataaac cagtagatct ggtttctttt gtggcgaaat ttcttctaac
     3541 tccttcagca tcgtttctaa aagaccttca tactgcttta cttctacttc agaaacacgc
     3601 cctaaatctg cattcaaatg aaacagcata ctatcttcgt agatggagcg gtctagtacg
     3661 ttgtcatcat ggctgaaagc atctttgatt gccaaaaagc gtttgttcaa aaagaaaatc
     3721 tgtaataaaa aagtatactt ttctggatta gaataaaata gcggcaatac ttcattatct
     3781 tccacgttct cataaaaagg ttttgtttct aaatcttggg caagcatttc agttagtgtg
     3841 cttttccctg caccgatcgt tcctgcaaca atgatcacaa ttatcggcat ccttcctgta
     3901 ataaaatctg ttcttcattt tactacttca tttatagaaa taaaagcctt gactttatct
     3961 gctccttaaa agctacttct ctaaaagtag ccaaaagtaa ctcctattca tgaaaataaa
     4021 ggctgtgaca aaagtcttgt cgcagccctt ttttcaaata aacagtattc tcctgccaac
     4081 acctcggtca caaggcaata ttcataaaac atgaaaagct gttttttaac attattcctt
     4141 gtaactcaga gctaaacggg agactcacaa cctctttatg ctctcaacat tttatctgtt
     4201 tttattcttc tattgtactt gatttgcgta caactaactg ccagtgcaga ttatgagcgg
     4261 tatcattgtc ttctactgcg catttcatga cacgtatcat cacactattt tcatagattt
     4321 tttctatttt tccttttatt ggtgattcaa ataaatcaga tttaaatgca tatgtttcgc
     4381 cgacttcaaa caattgttca ttttccataa gaatccctcc atcacctttt ataaggtcag
     4441 taatttttta acataaatca ctcgaaaaag cacaaacttg tcataaaaag tacttttcgt
     4501 atcaaaactg tcactttttt tggtaaggtt cttggaaaac gaagattttt ttaggagatc
     4561 atgacggttt tgatgtcaaa accacttttt atgaaacaaa agacgttttt tatttttttt
     4621 agcataaaat ttgtggtgga ggtacgtatg agatgaaaga taaagttgtg aacaaattat
     4681 tagaagcctt attcagcgga gacaaatcgg aagaagatat ggtgtatgtc caagtaaaat
     4741 ttgtcttaga agttttattg aataatcttg gaaaactagc ggtcgttcta gtcttttctc
     4801 tggtgacagg ctcatgggcg gaaacaggaa tcacctttct ttcttatatc tgcatccgca
     4861 gatatgctta tggattgcat tccgactctg aattcgtttg tctgctgtgg acactacttt
     4921 atttatgggg cgttcccttg gtgatgaaac atctgcaatt gactatctcc ttcccaatga
     4981 tggtcttttt gttaatcagc tgctttttgt tactgcttcg ctatggatca agaggtacag
     5041 caatcaatcc cattgaaccc gagaaacgtc ccccattatt aaagaaggcg atcagcatgt
     5101 ttctaatttt ttctctcatt acgttatttt tctcagcttc ttacttttct acctatttgc
     5161 tacttgggat tgttttagaa atagctacgt tgcttcctat tacaaactac ttgatgaatt
     5221 ttggaggaat ctttcatgaa aaaaacaatc attaaacaat taactaactt atctgacttt
     5281 tttgtatctg gctgctgctt tggtatgagt tctgaattca aaatccctga aaaattaaaa
     5341 aaataatacg ccaattgtgc tataatttgg taaaaatcaa tgggagctgt actttatgtt
     5401 tttatggtcc atagcgttgc aatatttgat ttacacaatt tgtatcttat tgattgacca
     5461 tcacatccga tacaaatatc tgtttgcggg agtcattctg atttcttgta ttttgattgg
     5521 atgggtctat tcgattttag ggatttttac tgctctaatt gctataggaa tgctgatgct
     5581 tacttttttc ttcttttcga cttcgcgtca acaattggtt tacgcgcttc cttttgggtt
     5641 attgacgtcg cttttaggag atcacttaac aagcatcggc gatttttttg ttttgaaatc
     5701 ttcggttatt gaaccaggag attcattgca gtattttcac attgtcttat ccgctttttt
     5761 atctgcttta ttagcttttt gtttaaaaaa atcgttagag acttggtttc acactgtgga
     5821 ccgccgtatg atcggtacga tcgggacatt gatattattt acatactata tcattatttt
     5881 ttatacccgt ttttctggtg aaacacctga tgtcttagct ttgaatacga gttttttcat
     5941 tctatatctg tgtgttggcc tgatcatctt ggtttattat tggaaaatct ctaataagaa
     6001 attagctgat cagttattag agcaacaagt caggatgcaa caggattata tcaaagatct
     6061 agaaaaaaaa ctatcaagac ttgagagaat tcaaacatga ttaccaaaat ctgctttttt
     6121 ctcttcacag ctatatttca gaaggcgact tagaaggatt acggtcttat tatgatcaaa
     6181 cgatattacc tacacgccag atgatgaacc tttttccggc caatctaagt atgttggata
     6241 atatgaaagt tcctgagatc cgtagtttac tgtcattaaa actcatgatg gcacaggaaa
     6301 aagggttgat cgtccagctt cattttcctg agccaatcga actggatacg aaacatacgg
     6361 taaaccttgt acgtatgctt ggtattatct tggacaatgc gattgaagga gctagtgctg
     6421 caaagaagaa aaaaatcgaa ttgaccatac tcaagaagaa tcattccgtg atgattcgtg
     6481 tgatcaatac aacaacaaat acattaccgt taaaccagtt gaaacaaaaa gggttctcaa
     6541 caaaaacaaa tccaaaaaac gaaggccttg gcttgtttat cttggatgaa ttgacaaaga
     6601 ccaatcctta tcttttcctt gaaacatcaa ttgaaaacca gcgtttttct caaacgattt
     6661 atatacaaat aaaataaagg agtaatgata tgattcccat ttatatttgt gaagacgatc
     6721 caaaacaatt agaagtttta tcaacggtga tcaaaaatag aatcatgatt gaaaacttag
     6781 acagttatgt ccatatttct acctctgatc cggaagaact tctcaatgca gccaagatca
     6841 gaacttcttc ttttggtatt tactttttag atatcgaact agaagacagt gaaatggatg
     6901 gtgtagcgat cggtaaattg atccgtgaat tagatccttt aggaaaaata atctatgtga
     6961 cttcccatac ggaaatgtcg atgaaaatct taaaaagcaa catcgaaccg actgattata
     7021 tcgtcaaaga agatctttat gatttaaaag aaaatgtcga gcatatcctg agcaaaattt
     7081 tcgaagattt tcaaatgtcc caaatccaaa aagatatctt caaaatagag tttaatgatg
     7141 agatcaaatt tttaccgatc aaagacatcc aatatttttc tacttcgcta ggagcgccac
     7201 ataaactgga agtccatttg actcatgccc aattacaatt ctatgagaag atcaaagaaa
     7261 tcgagaaaat gcatcggaat tttatccgtt gtcataaatc ctatgttatc aatacacaaa
     7321 atgtgcggtc gattaataaa aaaaccagag aagtcacgtt ggcaaacggc gagaccatcc
     7381 cagcctctat ccgtggatta aagaaattga tttcataaaa agaaccgaat agtttggacc
     7441 gactaaatga ccagccgatc caaacccttc ggttcttttt tgcctatcag tgcaaaagca
     7501 tttcctgtgc aatttcacgt ccatccattg tatctggata aaatgttggc caattctcca
     7561 tttctttcag caatacttct tgactttcat ttcctgcata taaatgaaaa tgttcggagt
     7621 cagccggtgc aatcgtgtga tcactgaatt gaatatatct aaaagcgcca ctttccttat
     7681 cttctgcttc gaatagatac cttacgccac ggtttcctgc ctcgtaggtc aagatttctt
     7741 tccctacata acgataattt gaacgtttcg ttgttccatt cttaaacgta aatgccatct
     7801 ctttctcact gatcttgatt gaagcaatat ctgtttgata gcccttcgta taatattctt
     7861 tatattcttg tgctgtctta tcctgattca atttttcttt atattcaaaa acaggatcaa
     7921 aagtcccatc ttctacatac gtatctactg tttgccaagt tcctgcccaa tctgaaagag
     7981 agcgatcttg tacatcctcg tcttcaaaat aaccgttgta gacgctcttt tcttttttgg
     8041 gggtcaaagt atcttctagc gggttttctg tctctgtcgt ttttttcaac gcttcgaggt
     8101 ttgcttccat gatagaaaga tagttttctc cattttctat ttgttcattc gtcaatcctt
     8161 ccaaaggatt caatacttct aaagatacac ctgcttcgtt tgctaacgtt ctggcaatac
     8221 tatctttggc gttttcttca aaataaatat agttgattcc atgttcttta acaaagtgtt
     8281 tcagttcagc aattctcgcc gcagacggtt cttcactaga agaaagacca gcaatcgata
     8341 cttgattcaa tccatattct aacgctagat agttgaatgc agcatgttgc gtgacaaaag
     8401 atctttgttt tgcttgctta aaggtttctt gataaagctg atggagtgct tgaagtttct
     8461 cggtataggc tgctgcattt tttgtccata cttcctgttt ttctgggtaa gcttcaatca
     8521 gctgatcacg tatgtttgct acctgcttga ttgctaaact tggagctagc catacatgtg
     8581 ggtctagctc atgtgtatgg ccttcttccc cgtgttcatg gtcatgatca tgtccttctt
     8641 cacttcccgg aagtaaaagc ataccttctg tcgcttttat cgtatggaca ttgccttctt
     8701 gtaatgtttt ttggattgcg gggacccatg tttccatgtt ttcatcatta taaacaaaga
     8761 tatctgtatc ttggatcttt gccatgtctt tagcagaagg ttcataatcg tgggaatcag
     8821 tccctgctgg aatcaataac tctacttctc cttcatcccc gacgattgct tttgtaaaat
     8881 catacatggg ataaaaggtc gtcatcacgc tcaatttttc tttactgtcc tcggctttcc
     8941 cacttgcccc gcaagcagtt aacatacctg ctaaaaccag catggccaat atacctatca
     9001 atcgtttcat ttatgacact cctcttctca tcttctttca tttgaatgtt ccgattcgct
     9061 tttcgcaaac cgtaatagtt acgttttagc aacaggattt aatttatcat atggttaaaa
     9121 gaactgtcaa gcgttttctt attttaattg atgagaaagt ttatatgaat gattgacgat
     9181 atttttgcaa tcaacctcta tcattttcct tttatacccg cttttgtcta taatgaagtt
     9241 atagataaag gaggaaaaag agtgaaaaaa gaaacagata caacgaatcg tttgatccgc
     9301 tttttaggag gaaaaacctc ttactatgtt ttaggaatag ttatcttact tgcgctgatc
     9361 atttattttt tccatcagat ctcgtttata ttcaagcctg tcggaatcat tatcgctact
     9421 atcttgcccc cattattgtt tgcactgatc ttgtattatc ttttggaacc agtcatcaaa
     9481 cgtttgagca agcacctttc gaggaacttg tcagtcatta tcgtttatgt gattatttta
     9541 tttttattgg ggcttggaag catatggctt attccttttc ttgaagaaca ggcaaagaca
     9601 ttgatcagta gtttgccaga tttgtttcaa gattttcaag agagtctccg acaatttttg
     9661 gagaaaacac cttttgccga ttcatttaat caatttttcg cttctattga cgacgtgacg
     9721 tctgatatag ctggatttat tggaaattat tgggaaagtg gcgcacaacg gatcagcaac
     9781 attttttcaa ctgttacagc tatttttatt actttattta ctggtccaat tgtcgctttt
     9841 ttccttttga gagatcctca aaaattttat cagtcagttt tagcgattgt cccaccagca
     9901 tttcgtacag attttaaaaa tttgacaaag attgctaatc aacaattggg ttcatttcta
     9961 aaggggcaaa tcattgcttc atttatcctt ggagcagtct actgggtttg tttcttactg
    10021 atcggattag aatttgctag tgttttagct atttctgctg ggttgttatg tatcattcca
    10081 tatattgggc cgtttatcgc cttctttcca ggtttgatca ttgcattcca agactctact
    10141 tttatggctg tcaaatttgt cattgtctgg tttgccgtac aacttctcca cggtgacttg
    10201 gtgattcctc gagtaatggg tgatcgttta cagatccatc cgattacgat cttaatcgtt
    10261 ttacttgtca tgggtgatct aatgggaatt gtgggcgtta tttttggtat tcctatctat
    10321 acgttagtca aattactcgt tacttttatt ttccgtaaat tcaaacaacg ctacaataaa
    10381 ttttatggcg ataaaggaga gtatgaaaac tcttcatttt ctgaagaaga ttattttaaa
    10441 taaaacacaa aacgtcgatc ttacgagaat agctcgtagg aacgacgttt tgtgtttttg
    10501 ttttaatttt tcagcaaagc aattgcctgg tatggtttta gctccagact ttgatgaaga
    10561 acagtatcgg aataattatc gataagaata ttggcttctg tgaatccttc tgggatggcg
    10621 atccttgtat ctttatcata gaaatttgtt aatacaagca gctgctgtcc ttcaaattgg
    10681 cgaagaaagc cataaacttc cggatgattt gcttcataag catgataatc tccttgtgca
    10741 acgattggat atgtttttct cagccgaatc aatttcttgt aataggacaa aatagaatct
    10801 tcagaagata gttctttttc tacattaatc tcttctagct tgcctccaac ttttaaccaa
    10861 ggtttccctg tagtaaatcc tgcttgttct gtgtctgacc attgcatggg tgttcgagag
    10921 ttatcgcgag attttgcttt gatccgacga aacgcttctt tttctgtgaa tccttgttca
    10981 aggagtaact tataagcatt caaactttct acgtcaatat agtcggaaat cgatgaatag
    11041 tctgggtcga tcatgccgat ttcttctccc atataaatat agggcgtccc acggttcaaa
    11101 tggatcatgg ttgctagcat ctctgctcct tgttttcgat actgatcgat agctacaaat
    11161 cgattgagcg cacgtggctg atcatgatta ttaaaaaata gagcattcca gccgttaccc
    11221 tcactcatct tttctcccca tgtatgaaat agtcgcttta attctgcaaa atcaaatgga
    11281 ggagtagacc atttattccc attttcataa tcgactttca aatgatggaa attaaagacc
    11341 attgataatt cttctctact aggttctgta tacaagatac aattttcgat cgtcgtagag
    11401 ctcatttcac cgactgtgat gatagtggaa tccgtcccaa acgttgcttg gttcaattct
    11461 tttagatacg tatgggtgat tggtttgtcc gtatattcag gtttgccatc attttcttta
    11521 ttatttttca attgttcgtc tttaccgata acattgataa catcgaaacg gaatcctttt
    11581 accccttttt ccatccaaaa acgaacaact ttgaatagtt cctctcttac tgcttggttc
    11641 cgccagttca agtcagcttg tgtccgatca tataagtgca aataatattt ccccgtatct
    11701 ccaaatggcg accaagcact tccaccaaat tttgataccc aatccgttgg ctcttctctt
    11761 aaaatgaaga agtcctgata atgctggtcc cctgctagtg cttttttgaa ccattcatgt
    11821 tctgtcgaaa cgtgattcag caccatatcg agcatgattt ctatccggta tttctttgct
    11881 tcggctatta gctgttcgaa ttcctccatc gtaccaaaga taggatcgat ggctgtgtaa
    11941 tcagagatat cataaccgtt gtctttttga gggcttggat aaatagggtt tagccaaatc
    12001 atgtcgatgc ctagatcatt cagatacggg agtttttctt tgattccttt taaatctcca
    12061 attccatcac cattactgtc tttgtaagat ttgggataga tttggtaaat gactttgtct
    12121 ttaaatgtca tggatattta cctccattca actgatttat tacctaccac aacttatata
    12181 tacaagttat catttattat tataactgaa ccgaaagcgt ttgtaaaatt tatctttata
    12241 cattctaaga ggtctgttgc ccaataaaaa acaagagatc agacatgtat ttgtctatcc
    12301 tcttgtttaa aatagcaaaa tattcttgtt tcttctataa atggtgttca aaagctttta
    12361 tctacggcaa tcagtcttct caaatgtaaa acatgaggag ctaattttat ttgagtattc
    12421 tttttgctcg atgcaggacg gcttttttac aacctctgat tcatggtgtt caatcagctg
    12481 tccttcggta ttagctcaaa aaacggcaaa atatgaaaaa ctattttgcc gtttgtttct
    12541 ctaatactca ggtcaaaccg ctgatttcac aacctctgtt tttattcatt cgatttcaac
    12601 gcatcaatca tatcgatatg ctttaatttg aaatgggtaa caatcatcac aataaccgta
    12661 aatacgatag ttaatcctgc tgataagaca taagcccacc atgtgatcac taatggaaag
    12721 atgacattct ccatagacgc ttgttgcaag atgaagtcag tcaatatata tcctacacca
    12781 aatcctccga tgattcctaa aagagtaaag atgatatttt ctcgaacaat gtacatcgtg
    12841 acttctttat caaaaaatcc aaggactttt attgtagata attcgcgtac acgctcggaa
    12901 atattgatat tagttagatt atacaagacg ataaaagcca gcagtcctga taatacgaca
    12961 aagattaaga caaccgagtc taagttcgcc attgattctt cttgcgtttc gatttgtttg
    13021 gacatgaaag acgtatttgt cacagcgtct gtggcaagca gtttctcgga aagcatttct
    13081 tcttcttttg ttgtcatctt atctgtacgc agcaaaaatg cattatccat catcgattga
    13141 tcagtaactg aagcataata ttcaggggac atataaataa agctacctag atagtttttc
    13201 acgatttctt ttacttcgac tttccattct ttttgatctt catcataaag cgaaatatga
    13261 tctcctgtag ataagtcaaa tagttctgct actttttgcg taatagcgat tcctgtttta
    13321 ggcaaggagc gtgggttctc ttcaagatca gttaaatgga taaaacgatc caaatcagct
    13381 gttttacttg gtacgatcac tgtcagactt tgcgaagcat gtcctttttt tctcaattct
    13441 acggtttgag tatgaatagc taggatctca tttacttttt cttgcttctg cagcatatcc
    13501 gctgcttttt gacgactatc ttccgtggat gaatccaatg taacgattgc ttgatagtca
    13561 atgatcgttc caaattgttt ggctgaaaca gaacttagag aatctttcaa tcccacgcct
    13621 gcaaccatca gcccggcaca tccagcaatt ccgataatcg ccataagcat tcttgactta
    13681 tatcggaaga gatttcggta actgattttt tgattaaagc taaggcgtga ccacagcgga
    13741 gtgatgtatt caagaaaaat gcgtttccct ggcttcggtg ctttcggttg aagcaatgca
    13801 gcaggccgtt ctcttaaatc tttgaataaa acgatcattg cagcgccaaa tgcggcaatg
    13861 aagaatgcgg cagctgcttg taaaatcggc ggccagtcat aaaaaataag cgcactccca
    13921 atatcatacc gctcgttaga cagctcaaaa atgatccttg gcaaaagatt cgttcctaat
    13981 atcgttccta aaacaatacc tatccctgag gctagacttg catagattgc atattttttt
    14041 gcgatttcaa ctttcgtata acctaacgcc tttaatgtcc cgatttccct gcggttttct
    14101 tctaccatac gtgtcattgt cgtaaaggtg atcaatgcgg caataaagaa aaagaaaaca
    14161 ggaaaaacat tggcaatcgc agcgatacga tcagacagat caccaaattc ttgaaaaccg
    14221 acattttctg aacgttcatt gtataggtat gatggtttag ttaaattttc aattttttct
    14281 gcatttcgat tcaattcttc ctctgcagag gccagttcac gttctttctc aactaattgc
    14341 ctttcttgtt cagcaagttg agcttcttgt tgagataatg tttgaacagc gattgttcgt
    14401 tgcgcttcag gaagctgctg gatagttgct gactgttgcg ctaactgttt tttagcatct
    14461 tctaaccgtg ttcttgcttg cgttgtttgt gctttgccat ccgctatttt ttgctgtgcc
    14521 ggttctaatt cttcgttggc cgattttttc agctcttcta agcgttcttc gggtcgatct
    14581 tgtaaatact tttctgcctt ttcttgattt tgctccattt tatctttgta agctttgctg
    14641 tacgtattca aattctttac gtttgtaaaa tcaagatata agacagaata aatatctgtt
    14701 ttaaaaacgg attcaggtaa atagacaaaa taatcgacgc taccatttcc gacgttcgcg
    14761 tatcctctct ccaaattgtt gatgaacaat ggagaacgga caaagcccgt gatggtatac
    14821 tctttttctt tcaattcatc tgaatcaatc tgataaatat caccgatttt atacccttca
    14881 tcttccgctt tttcatccaa tacaagctgg tttggttttt ccgggagttt tccatcagtt
    14941 aattgtagct tgttctgctt gttatttttg ttataagaaa atatttgaat cacttcgttt
    15001 ttgccagtat tggaataata gatctgtttt cctgtttcta cttttgcatc tgggatcttt
    15061 tctgcttgag caatatcttt ttgtgtcaag ccaccagtag aaacgatttg caaatcagaa
    15121 agtcctgctg taccaacata gtgatccatc gttttttgca tgacaggtcc agcagttttg
    15181 acacctacaa ataaaagtgt tcctagcatg acaataagga tgattgcaat gaatcgtcct
    15241 ttagattgcc gaatttcgcg aaaacctgct ttaagatatg ttcttgtttt cataaaatcc
    15301 ccctaccata caatctcatc aatggatgaa ggatgatcat ttaattcaac agaccttact
    15361 ttagcatcat taatgtgaat gactctatca gcgatgggcg ctaaagcaga attatgtgta
    15421 atgatcaaaa cggtattgcc gtgttgtctg ctagcgtttt gcaataattt caatacttgc
    15481 ttgcccgttt caaaatccag cgcgcctgtc ggttcatcac ataaaagaag tttgggattt
    15541 ttagctagtg cacgagcaat tgaaaccctc tgctgttcgc ctcctgataa ttgggacgga
    15601 aagttattca atcgatgagc taggcccact tgcctcaata cctctacagg atcaagcgca
    15661 tcaggagaaa cttccgttgc caattccaca ttttcttttg ctgttagatt aggaacgaga
    15721 ttgtagaatt ggaaaacgaa ccctacatct gttcgtcggt aagcagtaag ctgtttatct
    15781 gaaaattgcg caatatctgt gtcatcaata atgatctgac cttcatcagg tgtatccatc
    15841 ccacctaaaa tattaagaat cgttgacttt cctgctccac ttggaccaag tataatcact
    15901 aattcgcctt tttcaattga aaaagaaata tcgtcatttg ctgtaatggt cgtttctccc
    15961 attttgtatc gtttgtattc attttttact tcgacatact tcactctgat tcctccattt
    16021 tcacgatatt tctcgctata tctatgcatc gaatgcgttt tctcacactt atttatttta
    16081 ccactgaatt tctctagact aaagaaagga atcctttaat ttagttgaca aataaacgat
    16141 ttatgattta cttacataaa aaacattgtt atttgaaaga aggaacatca tgaatgattt
    16201 aaaggaaaat atgatttttg atttatcaaa aactgctttt gtcgcgatcg acatgcaaaa
    16261 agagatcgta aataacggta cactctctcc acacactgca gcatctattc tgacaaacaa
    16321 tgatttgtta gtaagaacat tgaaacgtac cgctgccttg aaagttttag tgaacgtaga
    16381 catctccact ttcccttatt tgagtcaaca aactgatatg ggtggaatga ctgcttctgt
    16441 acctccagaa ttcactgatt tacttttgaa ggattctttg aaagatacag ataatatgtt
    16501 gactatcaca aaatacaatc caagtgcttt ttttggtact tctcttgatc ttcaacttcg
    16561 ccggcgtgga atcgaaacta tcattttaag cggtgtagcg acaacaaacg gtgtatatgc
    16621 tactgcatta gatgcctttc aacacgggta ccatatcgtg cttgctgaag atgcttgcag
    16681 tgatcgtgac aaagaatccc atcaattgtt cataaaaaag atatttccga aaactgcacg
    16741 agtacgctca acgaaacaaa taatcgaagc tatccaacaa agcaaataag tactggcaca
    16801 cgtgattttc atttacttct ttttgatttc atgggaaaat aaccacagga tttagatagg
    16861 agtatgaaca tggtgaaaaa aaagatcaca atcaaagaag tcgctaaact ttccggcgtt
    16921 tcaatcacaa ctgtctcctt gatattaaat ggaaatacgg agaaattcag tccgaaaact
    16981 gttcagaaag ttttagctgc caaagaagaa ttaggctatc agcctgacta ttttgctaga
    17041 caaatgatta ccaaggaaac gaaaacaatt ggtgtactcg ttcctgatat cacgaatcca
    17101 ttcttcagta cactgatgcg aggaattgag gatatcttgt ataagcagaa tttcgtcacg
    17161 atattatgta atgctgattc tgatcatcaa aaagaaatcg aatatctagc cgagctcaca
    17221 cgtcgaggtg tggatggatt cattatcgcg acttctgctg tctctacaga tgcaatcaac
    17281 gaaaatttga aaaaacaagg ccggcccttc attgttttgg atcagaaaaa atctgaagga
    17341 tttagtgatg ccgtacgaac agacgatttt cgcggtggtt acctagcggg catgcacttg
    17401 cttagtctag gacatcaaac gatcgccctt gtctatcctg aaaatccacc ggaaaatgtc
    17461 cacgctcgga ttgaggggtt taaatctgct cttgatgttt accaaatccc tcacgaccaa
    17521 ctgatcctct tacctacaca gttctcaaaa caaggtggct accagatcac agcagaactt
    17581 cttgattctg ctgcaactgg tgtgtttgct ttaaatgatg aattagcttt tggattatat
    17641 cgcggattag aggaagctgg aaaaagcatc cctgaagact acagcattat tggctatgat
    17701 aatatagata tgtgcgagta tatcaagccg aaactgacaa cgatcgcaca accaatcttc
    17761 gaattgggac aaacatctgc caagttattg ttagatcgga tccaattccc agaaaaagaa
    17821 tgggaagaaa aaagattacc tgtacgatta gaaaaaagat tttcaactgc acccttgaaa
    17881 tagctttcaa ggtgtgctat atttttatcg aactattaaa acgttttact aaaacgtttt
    17941 aaaaaataat tttcccatca aaataaatga gatagttgga ggtttgtaaa atgaacacgg
    18001 ttacagtaat tggaagtatt aatatggaca ctacccttcg tttaaccaac atgcccaagc
    18061 caggcgaaac gatgcatgcg catgagattt ttcacgctgg cggaggtaaa ggtgccaacc
    18121 aagcagtggc agccaaacgt tcaggcgcac ggacatcttt tattggaggc gttggggctg
    18181 acagcgaagg acaacagtta ttagatctac tgacaaaaga aaacatcgat acatctggga
    18241 tagctgaaat ccaaggcgcc acaaccggac aagcaatgat tatggtagac gcagcaggag
    18301 aaaatagtat cttgatccat gcaggggcaa ataatgcttt ccatgaacaa gaagtcctaa
    18361 aaaacaagca actgattaca aacagtgact ttattattgc tcagtttgaa agtagcttag
    18421 atgcgacgat cctagctttt tctattgcaa aagacgcagg aaaaacaacg atcctgaatc
    18481 ctgcaccagc tcgtgaaacg attcctactg aactacttga aaagacagat atcattatac
    18541 caaatgaaac agaaacagaa atcattacag gaatcagagt gacagatcat aacagtttgg
    18601 tcgcagcagc cgaaaaactc catgaattag gtattggaac agtaatcatt acactaggca
    18661 gtgccggcgc tttctatcat acagaaaaag aacacggtat cgtccctgct tttaaagtgg
    18721 atgccgttga cacaacagcc gcaggtgata catttattgg cgcattaagc agcacacttc
    18781 agccagacct tagtaacttg aaagaagcga tcctttatgg aaatctagcc tcttctgttg
    18841 ctgtgcagtc ttatggtgcg caaccttcta tcccttaccg cgaagcttta gaacaatcag
    18901 cagtctaaaa ttaacaatga gaggaagaaa caaacatgaa aaaaggaaaa gtaatcaatt
    18961 cagatatttc acgagtaatc gcacaaatgg ggcactttga taaattaagt atcggggatg
    19021 caggcatgcc tgtccccttt ggtactgaaa aaatagattt ggctgtctca aacggtcttc
    19081 caagtttttt atctgtttta gaaaacgttt tagaagaact tgaggtacaa tcgattgaat
    19141 tggcggaaga aataaagaca atgaacccgg aaatattgga aaaaatcaaa ttattgttac
    19201 cagatacacc gattagcttt atcccacatg aagaaatgaa aaaagagttg aataactgtc
    19261 atgcatttat tcgtacaggc gaaatgacac cttacgccaa tattatatta gtgagtggag
    19321 tggtcttcta atggaaacga caatgaatcc tgaacagatg gtactgtccg agcagattca
    19381 tatgctgatt gaacagttgg gaggaaaaga caatattgat tctgtccttc catgtgcgac
    19441 tcggcttcgt atcaaattga aaaaacagcc agtagccaat gcagaaaaat taaaacagca
    19501 aatcccttcc attaagtatt tcattttact cgatagatat gcagaaataa tcatggatca
    19561 gggattggct cctgcttaca aggaattgac gcgtcaaatc gatcattcag ctccgaaaga
    19621 aaagctaaat ccgatcgaaa aactatttgg tttgatatcg gaaatcttta cgccgatcat
    19681 tccgctgttt gccggttctg gtatattaaa aggtctggtt gttttagcga ctacgattgg
    19741 ctggcttagt gaaacaagcg gaacttatca tattttgtct gctgcgtcga atgccgtctt
    19801 ttattttctg ccaatctttc ttgctttttc tgctgccaaa acgtttaaag tgaatggata
    19861 tattgcggct gtcattgctg cagcactgat tgaaccgaat ctgacctctt tactttcaga
    19921 cagtggcaaa gcagctactg attttctggg gattcctgta gtactgatgc agtatacgtc
    19981 tactgtcatg ccggcgattt taggtatttt cttttattct tttgttgaaa aattcctcaa
    20041 aaaatatatt cgcgaaaata tgcaattagt atttgtacct ttactttcat tagttatcac
    20101 ggttcctttg acgttaatgg tattcgggcc tgcgggtgtt taccttggcg aaggtttagc
    20161 tgccgcaatt acttggatga tggatattaa cggaccgatc agtggcgcaa tcatcgctgg
    20221 tggttggaat attttggtaa tatttggtat ccaatgggct gtaaaccctg tcatgatcag
    20281 taatatctct gcttatgggt tcgaccgaat cgttccgttg acaggagcag ccaattttgg
    20341 aatggctggt gcagctttag gtgtatttct gcgaagtaaa cgttcaaaaa cccgttcgat
    20401 ctccggttct gcttttgctt cgattttact tgcgggagtg accgaaccaa ctgtttacgg
    20461 aattgcgatc ccattgaaaa aaccatttgt tgctgcttgc attggtgcag ctgctggtgg
    20521 agctgtaatg ggatttgccc aagtgaaagc gatcgctttt gtatttggta gtctgaccac
    20581 attgcctgca ttcatttccg gtactttttt ctggtactta gcaggactgg ctgttagtct
    20641 agtcgtagca atgatcacta ctctcgttag cgggtttgat gaagacctaa tgtcttatga
    20701 atagttaatg aaaaagactg aagtatgaga tgtttatcac atatttcagt ctttttcttt
    20761 ttaggatcat tatttttata aatttttgtg atactttcca aactttggta taatttacat
    20821 atgcataacc atttttatcc ccacttgttt atccccaaac aaaggtggtc tatgcaataa
    20881 aatgaacgtc aaagaaaaac gaatgaatgc tcgttgctta tttacaaatt gttttattta
    20941 gaatacacag acagatttat gaaaagaaaa agcttttcga cacgattatc tgttccaaaa
    21001 aatgtctaat gaatgctgaa taagacagaa aatcaatgaa aggaaaagga ctagtttatt
    21061 atgaaaaata aaaaaacgat acgtttgcta gctgctactt ggctgattgc tccgtctgtt
    21121 ttgtcgacca ataccgtatt tgccgtagat aatcaaatag ctgatcaaac agtcacaaca
    21181 gatacgacta catccagctc agctactagt gaaacaacgg attcttttac agaagaccca
    21241 actggaacaa ctaactcaac aacaggatcg accgagccaa ctgaaattga tccggctgat
    21301 ccatcagaaa atgaaaagcc agccgagaca tattccctta caattgctcc ttctttgatt
    21361 ggtaagatcc aactgactgc ttcgacagcg gattcccctg aacagcaacc tttggatatt
    21421 acggaaagtg gaacggtaga aggtttatta gcggaaacga aggtaactta cactattacg
    21481 ccagctgaag gtgaacaaat tgcttcagtc gctgttaatg gtgccaaaga agtaaattat
    21541 gatgcaaaga cctttacagt aggtacgaac aatttatcta ttactgcaga atttaaagct
    21601 ggaccggata cttcaacaga gaaaccaact gatcctagtg aagaagtccc tagtacacca
    21661 gatccggaaa cgccaaacaa accagatgtg ggtaataaca acaataataa tggttcaaat
    21721 aattcaaaca ataataacaa taattcgaac agcgggaatt cttcgaatca aacaaaccca
    21781 tctggatcga ataacaatgg aaatactcag agagaaccaa accatccaaa caatggttca
    21841 tcgaatggcg gaacgaacaa tgcttcatct cgtccaaata cagcaaatca aagcggtata
    21901 gagaatccat cttctgcttc ttctgatttt gttgtaaaat caccaattga tgctgtattg
    21961 cctacaaata caacgaatgt ccaacaagca atcgttcgag aagcattcaa gcatcttgga
    22021 aaaccatatg tatggggagc aaaaggtcca aatacttttg actgttctgg tttgacttat
    22081 tacgtatata tgaaagcaac cggtcattat atcggtggct ggacaggcga acagcaatat
    22141 gcaggtacgc agattccagt aagtcaggcc caacctggcg acctcgtctt ctggggacct
    22201 tcttccggtg ttactcacca tgtaggtatc tatattggga acggacaatt tatccatgcg
    22261 cctcaaccag gagataaagt tcgagtaact tctatttcag atttcacgcc tgattttgct
    22321 gtccgagtaa acttagcagg tttacctgct gcttcaggtt cgctgacagg cggctcatct
    22381 attttagatg gattagatgg ctcgttccat ttcagtcaaa accaaacaac tgatcagttc
    22441 ttgaaaaaga ttgcagatga tgcacaggaa atcgggcaaa aagaaggaat ctacgcatca
    22501 gtcatgatgg ctcaagctat ccttgaaagt ggatctggaa acagcttatt atcaagcgaa
    22561 ccaaatcata acctttttgg tatcaaagga tcatataaag gaagcagcgt gaccttcaat
    22621 acacttgaac aagatagttc cggacaaagc taccaaatcc gcgcacaatt ccgtaaatat
    22681 ccttcttaca aggaaagttt ggaagactat gccgacttga tcaaaaatgg actgactggc
    22741 aatcctgatt tctacaaacc aacttggaag tcggaaacaa aagactacaa agaagcaacc
    22801 aaatatttgg aaggacgtta tgctacagat cgccaatatt cacaaaaatt gaacgcgatc
    22861 atcgaagcgt acgacctgac aaaatatgat gaaccgaaaa aagaagcagc aacaactgaa
    22921 gaagcaaacg ctgaaatcct caatatgtct aagcgattcg atgtgccaat caaatggaca
    22981 acagatggcg tgccaatcac aggattagaa ttttcaacga taaaacgcgt caacaacgct
    23041 tcttccatct tccgtgtcgc ttcaatctgg gatttgtgga acaattttac ggcaagacag
    23101 ataccagaaa caactactcg tacagttaaa gctgcaactg ttcctgtact aaccttgtta
    23161 agtttagaca aatcattctg gcttgatctg cctttaaaga aatagaataa attaaaaagg
    23221 ggatgtgaca ctgtcacact ccctttttaa tttattctat ttctttatat ttattttgta
    23281 ttccgttaca aactcgcgta cttggttagg ttccagagtg acatctccaa aactttcaag
    23341 tcgctccgct cctggcagtt cttgagtctc aaatgtgata ccgccatgat ttactaattt
    23401 attcccgcgc atttccggtc catcttctcc aaaatttgct gtaaaaatca cgattcctga
    23461 agcatctgtt tttacttgga tcgatacttt ttcatctggg cttgtcaatt ccgcagcatt
    23521 tagtaaacca gattgttttt tcaacaaaaa tggatgatcg atgccgccca ctatcattga
    23581 ttggcgaaaa tcactggcaa agacctcacc taatttttta ggacgttgga agtcaaatgc
    23641 tgtgccactt actgaaacta cttctcctgt aggcgttgta tctttattga gcgtagcaaa
    23701 taatcggcta ttcaaccaaa gtatatgttc gtcgattgac tgtgctggat caccggttaa
    23761 attgaaatag acatgatttg taggattgaa tactgttttg cggtcactga tcccttggac
    23821 cgtcactcgc catgtatcat cgttcgtcag cgtataccgt acttctacat ctaaagttcc
    23881 aggaaatccg ttttccatat ctgggctagt ctgatagaaa atgaccgatg cttcgttttc
    23941 accattgatg actgtataat gccactgctt ggcttcaaag ctaggtgcac caccatgtaa
    24001 acaatgacca gtgtccgggt ctgtttttac ttcgaacgtt tcatcatcta atttgaatgt
    24061 gccattcgta atccgtccag ccatacgtcc gattgaagca ccgatataag ggtctttttc
    24121 tagatattct tttgcttcat caaaacctaa gatcaactct cgtttttcat tatcgattat
    24181 tgtttgaaaa tgaacaaccc gtgccccaag atcactgaca gacaaagatg tcccattttg
    24241 attcgtgatc gtaatcaagt gatagttttc gccaaaattt tgttcattga tttccatgtt
    24301 ccttgcaccc tcttttcttt catttgcact gattccagca tacatggaaa ccgttttctt
    24361 aacagcttat tccgtgagta acgagaaaaa atttactata ttctaataaa agaccgtgaa
    24421 aaaaaggttg tgacaaaaat attgtcacaa cctctttttc cgaacaaacg gtgttcaaaa
    24481 gcttgcatct gcggtaataa gcccaaccaa acgaaaaata tgaggagcta tttttgcttg
    24541 gctgttctta ttacttgatg caggacagct ttttcacaat ctctttttca atacgattcc
    24601 agtatataac catgtcgtca gtacatagta gatgaaatac aatacgaaga atatcgtaaa
    24661 cggaacccaa atatctttgt atggattttg catgaataga ccaaacattt gtaatccgaa
    24721 taagacatgg actacaccta agattcctgg tgctaagaat aacacgccta cttctctacg
    24781 gatcgattgt ttaagcaacc cgcgtcgtgt tcctatcttt tcaagcattt cataacgagc
    24841 aatgtcactc ttgcttcctg acaagatctt gaacatcaaa cagctagcaa gcatggtcaa
    24901 gaaagctaaa cctaggaaga atcccataaa ttcaaaacca gagaatagac cattatacac
    24961 ttcatacatt tcatatttct ggttgctgta ctctactttt tgcaaagatg gattgttcat
    25021 tttattttga gcaacaagtg tttcgattgg tttcaggttt gcttggaagt cttttacctg
    25081 aactagctgt aaagtggatt gtggcaagtt cagttgatca aattctgatt gactgactac
    25141 cttgatttct ttttcttgct gttccggcaa ttcatagctt cgaagttcct cttgtacagt
    25201 cagttcattc atttttttag caggaacttt ttctttcgtg atcttcggcg gtgttccatc
    25261 ttcatgtttt atcatgatca atggttgagc cgcaaattca cttgcattat agtaaatcgt
    25321 tcccgcatct tctttttgag tataagaagc agaaagtgtt ggtgaaagtt ctttgatttt
    25381 ttgctgatct tctgcccgag gattattcat cactagatca tatccagaat tgttttctgt
    25441 caagtctgca atttcatttt taaaacctaa tcctaccgtc aaagcgccca gtgccaaggc
    25501 aaacagcata gcgaccattg agagcatttg tgtatattca cgaatacgaa agtttaactg
    25561 tgacaatgtg aaattgttca attttttcaa tgaaatctgt tctgatttct ttagtaatga
    25621 taaaaagaaa atgatcacag aatggaaaat gaaataagtt cctaatacga tcgtaactaa
    25681 ggctacccct ataccaaaga cttgataggt ccccacgtgt ttcatcatat agtaaccgca
    25741 gcctagaaaa gcaattccca gtactacttc aaggaaaaac aagaatttat gctgcttgat
    25801 tcttgttggt gtctgatccg cacgaatcaa tgctaaaatc ggttttttga caatcgaaaa
    25861 agcattgaca acagcagcta ataaaaacaa aacagcaaaa aacaaaacag tgatcaacaa
    25921 cccgtgaata ctaaaaggtg taaaatgcga aatattgaga tctaactgat ccactaataa
    25981 tcggtggacg atacttgtca atcctacacc gacagctgaa cccactaaag tagctgcgat
    26041 ccctactaag aatgtttcag aaaaaatcat ctgtgcgatt tttctgcctt ttgctcccag
    26101 catcataaac attgcatagt ctttttgccg catcgtcatc aaaaaggaat ttgcatataa
    26161 aatataaacg aatgtgatga tccctagtaa aacagaaccg aatcggaaaa tgataactgt
    26221 agccgcaacg atcgtattac ttttcaaaaa agcttcgttg cttgccattg attcaaacat
    26281 gtaaaaaata gcagatgcca taactaatcc tgagaataac accaagtagt ctcttaaacg
    26341 gctcttgatc ccagtaagtg ataatttcca aagcatagtc aatctccccc tactgttcca
    26401 agtttccaag aatagatagt atttctcgat agaaggaatc acggctttga tctccacgtt
    26461 tcacttcttg atggataccg ccatccttga tgaataaaat acgttggcaa taacttgcag
    26521 aaaacggatc atgcgtcaca agaagaatcg atacatgatc ttttgtattc aattcgtcca
    26581 tcgtatctaa aagatcccgg gcacttttgg aatccagcgc acctgtaggc tcatccccta
    26641 atagaatcgt tggttgtgtg atcaatgcac gtgcggcggc gacccgttgt ttttgtccac
    26701 cggaaatctc agaaggatag ctttccaaaa tatgagagat ggataaacgt tctgcaattt
    26761 tttggacacg ttgcttgatt tcttttggtc tgacgccttg taaagaaaga ggaacagcga
    26821 tattttcttg tgctgtcaag ctttctaata aattgaaatc ttggaaaata aagccaatct
    26881 cattcgcacg aaaatctgct agttgatttc cttttaatgt ggtcacatct ttttgattga
    26941 ttcggatatg cccatctgtt ggtttatcta atgtggataa aatattcaaa agtgtcgact
    27001 taccagaacc agaagcgccc atgatcccaa taaattcgcc tttttctaca tcgaagctga
    27061 tgccgcttaa tgcttgcgtc tttttctcat tgttttttcc gtatactttt gttacattct
    27121 gtacttcgac tattttgttc atttctttcc ctacccttta attagttttt ccagtgctgt
    27181 tttcggcacg tctttttttt cgacttcttc atacgaagtg acacctttat ttttgttcca
    27241 ggtgattttt aaatatgctc ctttacgaag cggtcgagtc aattgtccct tgaagtccag
    27301 ttctttttcc ttaccctctt tcgtatagcc aggcaggata tatctatagt tgactgtttc
    27361 ttgtccagag tctgattttg aaactgtttt tgtaccatct gtcgtaattt gtacatagta
    27421 ttcttctcca cccataacta cgtaatctgc gattttcacc cctgcaagta ccacaacgat
    27481 gaaaacaagt agaccgatca gaagtttttt cactttttcc ccttctctct tactttatat
    27541 actgattata gaaaaaagcg aacaattctg ccttcgaatc aactatcatt cttctttcaa
    27601 ttttgtcatt ttctttaaaa caactaaaaa aagagttcaa gacaataatc cgtcctaaac
    27661 tccttcttcc tatcttacaa aaagtatgtc acttacggtc tttcatgtcg cctgtattga
    27721 taacaggttg cgttcctttg tctgtaatga ttgagacaag taaattattg atcaattgga
    27781 ctttccgatc atcggtgaaa ttgatttctt gtccatcttc gatttgctct aaggccattt
    27841 gagtgattgt gacagctcct tcaacaatgg tttgtcgagc agacaaaatg gcttttgctt
    27901 gttgacgttg gagcatggca ctagcgattt ctgttgcata ggctaaatgg ttcaagcgtg
    27961 tttcgattac ttcgacacct gctactgcta aacgctcttg cagctctttt tgcaactcgt
    28021 cagacactgc cgtcgtgttt cctcgaagcg tcaaatcatt ctcattgaat gtatcatacg
    28081 ggtattggct agcgatatgc cgaatggctg tctcactttg gatttctaca aaatcttgat
    28141 aatacgctac atcgaataat gcctttgctg tatcaacgac tttaaagact actactgctg
    28201 agatttcgat ggggtttcca tccaaatcat tgacttttaa aacagaacta ttgaaattcc
    28261 gaactttcaa cgaaacagtc attttttgtg ccaaaggtat cgtaaggaaa aagccatttt
    28321 ctcgaatcgt acctaaatat tgtccaaaaa acaaaattac ttttgcttga ttaggactga
    28381 ctacagttgc cgaacttaac aacaataacg tgatcaacca aagaaaaata cttaaaaaaa
    28441 gtgcccaaac tttcgcttgc cacataccta aatagaagaa aaacaatcca actaaagcta
    28501 atacgaccaa tccgacaatc cctgcataac cattgatata aaatgctctt ttttctctca
    28561 tgctacttcc tgcgctcctt tatccttcaa taaatatcta atgttacttt tttaattttt
    28621 ttttcgaata cgcgccatta caccttctag ttctaactct ttgtcttcag tgatgtacca
    28681 accgcttgcc tgtgtccctc cggctgcctg cggtaaataa tccaattttg ttcgaaccca
    28741 gtgcttttct tctgtaaaat agtcttctac caagacctct agatccatcc ctgctgaaag
    28801 aggcaaatct tcccgaacag atttaaagat aaatcgttcc ttcttcccat catacttcaa
    28861 tattcctgta tcgataatcg gtaaagaata ataatccagc tctttcttca ccgtcaataa
    28921 atgtttgaaa acttcatggt acacttgctc taattggcga ccttctgaat tgttcgggta
    28981 attaaccatc actttttctt tgtctggatc atagaaggtt tggcttagtt gagtgatata
    29041 agtatgtaat ctttccattt ctgtttttaa cttttctctt tgaccttctt ctaccttcat
    29101 atactctttc accctgtttt ctttttagat attttctttc ttattttact atagttatgt
    29161 gcgttaagcg atgaaaaaca gcaaagattg gaaggatctt tgctgttttt tcttaaaata
    29221 tccagttgag tacaggatca atctgtttca ttgtcctctt gatccgtcgt aatattgatc
    29281 gatgtgtctt tagcagtgat ctttagcttt ttctgtcctt gttctaacaa agtatttgtt
    29341 attggctggt agtctttttc aatataagat tcaccagacg tttggatagt atagccactg
    29401 ttttccatct catgcaaaga taaattgcca ccgtttagga tgacttttcc ttctttgctg
    29461 atcaaactgt cttctagatg gaagttgctg ttttcacctg tgacgatcaa gttatccaca
    29521 ttggcctcat ctaatcgaag tgagcctaat tcatctttcg cagttattgt tcctcctgta
    29581 aattcattga acgataccca gccatcatgt gtcttagtat tcactttttt gattgatact
    29641 tcgttgatat caattgcact attattccct tcgattgtca attcagataa ttcatgatct
    29701 gcagggacaa caatagtgat ttgtgcactt gtgtcttcta aactaatgat tgcacctgtt
    29761 gattttttga ctgcattcac agtcaacacg ccatttttct cctttatttc tggcttttct
    29821 gtcttatcat aagtcgtttt tatctcaaaa tccaatccgc gtatgaccga aactgtttga
    29881 ttttctgcat ggatgacgat tttgtttgca tccttgattt tttttgtctc agtaaccata
    29941 tcgatcaacc gaggaccatt atcccaagtc agactctttt gagcgcctaa tgtataagtt
    30001 gcacctgcta ggaggccacc agtaagcatc agaccaatac cggtaatcaa aaaatgtttc
    30061 aatctcaatt tatgtgtcct ccttcaaacg cccgctgaat gcagatctct ttttgtaata
    30121 aaacgtcgtc ccatccattt aacaaagttc atcatgacat aaaaaagccc ttttgttcct
    30181 ttcagcaaca gtggcgaaat aaatactgcg cttcctgtgg cgaacagacc gacaccgata
    30241 aagaataatc cactcagaat cgattgtcca aacacactga ttcctgagat gatcatgaat
    30301 aggccaacac ctaagatact gatacataaa acatagatac taaaaatgag cgctagtaaa
    30361 gcaaccaata gtcccccaat aaccaatata aaccccagtg ctagtggaat gaggacagga
    30421 gaagcaaata aaccgataat gattaaccaa accaggcgaa tttgtctttt tggatttttc
    30481 actaactcgt tttctgcttg ttcttcttct gaaaagtaac tgatttttaa ttttaaggca
    30541 aactgctttg gtgtaccata ttcatcaatg atctgatcta atgtttttcc agaatctaaa
    30601 aaatattcct cataatactg gatcaaatca aaacgatcgt cttcaggaat ttcttgaaga
    30661 tgatccacaa cttcattcaa atattcattc atttgtgctc tcctccaata accggtctaa
    30721 agaatctcga aaaacaatcc attcatcaat aatttcttct aaatgacgac ttcccattgg
    30781 tgtcaacgag taatatcgac ggtttctgcc ttcaaaaggt tcatcatagg tctcaagata
    30841 tccttctttt ttcaatcttc tcaaaaccgg atatagtgta gattcactga cagagagact
    30901 ttcttgtacg atttttgtta aggcataccc atacatatct tccttgctta atgctgctag
    30961 cacagtacca tcaagaagaa cagttggaat ctggatgtgc attacgtcac cttctattct
    31021 caagtgtaat attttatttc aatctatatt atacaacata taatatagtt tcaaaatcag
    31081 tttgtcaaat acaaaaaaac tgactaaaag atttgatcct ttttagtcag caaaaaatgg
    31141 cttctctttg atttttatta taacagtggc ataatccaat ttgtccacat ccagctcagt
    31201 ggcatgataa cgatcattgc aggtatcatg tcagctactg ggaacatttt cacgttgatc
    31261 attctaaaac cggtagcgac catcaagaat ccgccgcaag ctttaaaatc taagatcatg
    31321 tctggtgtag tcaatggata aataaatttt gccaataaga acaaaatata aaaaataatg
    31381 aattggggaa ttgctatcac agaaacgaca taccctaaat tacacgcaaa aatagctgct
    31441 gtgaaaaaat caaggacaga tttagaaatc aaaatcgtac tgtctcctgt catcccagaa
    31501 tctaaacttc catagatccc cgtaccactt gcacaaaata gaacaatgac cgtcactaat
    31561 gtgctgataa attcatcgtg ggtcatacca agcttttcac tagggaagat tttagaaata
    31621 ggtacttgca tcagcgcagc ccccttattt atcccattac ctaaatgaac aatcaaacca
    31681 atcgctgttc ctatcactaa agtaaaaata acagccggca tatttttcat cggcgcaatg
    31741 gaatagattc ccatccccat cgaacacaca ccaaaaacca tcgtcagctg tgctttaaaa
    31801 tgttcactta atttatttcc tactaatccg ccaattagtc cgccaaacaa aacggaacct
    31861 acattgatca aaactccagt tggcatcaaa aaactcctct ctttttctac gaagcgaaaa
    31921 aaatcagaaa aatttctgta attattgctt tcgctgcaag aaagattgta acagacagag
    31981 aagattacac caattcattt tttgtgttaa agtattcttt attggaataa gtaggaggaa
    32041 tatgatggat atccataaat tcgaagtttt tcttgattta gccgaaacaa tgaatttcac
    32101 caaaactgct gatcgacaat tcaccaccca aggaaatatt tctaaacaga ttctttcgtt
    32161 agaaacagaa ttagacgtca aattattcga acgcgcccat agaaaaatcg aattgaccga
    32221 agctggaagc ttattgctcc catatgtaaa aaatgtcgta gaacaatacc atgctatgca
    32281 agaagtgctt gaaacctata cgaaagacaa caatctttca ttaaatatct taacgatacc
    32341 gacaatgatc aattataaag gtttttccaa aatcaccgag tttttgaaac gccatcctga
    32401 atttacagtc cagttgaaag aagtggaaag tgtcgaatta acttacaatg acgccaatga
    32461 acatagtgac acgatccact ttgctagaag tttccaggcc ccaccaagtt cgattgagtg
    32521 gttgcctact gaaacagacg attttgtagc agttctacct aaaaatcatc ctttagctag
    32581 taaaaagaaa ttggatctaa gcgaactgaa aaaggagaac tttttgctcc ttggccccac
    32641 tacgaacttg tatcaacctg tactagatct gtgtcgcgaa gctggatttg aaccaaaaat
    32701 ctcttataaa ggagcaagaa tcgacttgat catcaatatg attgcaaatg acatggggat
    32761 tgctattgtt atggaaaaaa cagtcaagaa tctattaaaa gaaaatactg tgattctccc
    32821 tatttctcca acaacagaga gttatcttgc atttactcgt aaagtcggtg agcattcttt
    32881 ggcttcagat acattttggg agtatttaaa tcaagaagaa aactaagccc tacattttct
    32941 gtccatctat ccacccaaaa aaagagagcg acgcatgact ttcgctctct ttcttgcatc
    33001 atgtccttgt ttcaatgaca cctctaacat ttctcgtagt tcaataagaa agcagcgatt
    33061 tttatgccaa aagaaccgta agaacatttc cctaatcaca aaaaaacgac taaaaacccc
    33121 taaaaacctt caatagaatt tttaggggtt ttattctttt tcctattgtt tacttaaccg
    33181 tatcattgct gtcgttccta ctccttcgat actgctataa tcaatacgtc catcatgcag
    33241 ttctagaatt tttttaacca gtgaaagtcc tagcccattc ccagaaattt gacgacttgt
    33301 atctccttga taaaattttt caaacattcg atctctggtc tcttcattca ttcctacacc
    33361 tgaatcggtc acttccagta caatctctgt ggctgtctca aatagtttga tatgaatctg
    33421 tccattgatt tgattgtact ttatggcgtt atccatgata ttcagccaca cttggtacaa
    33481 aaactcttca ttgcctgtgt aatttactgc agcaagttcg atatccaatt ctagctgttc
    33541 tttctcccat ttaggctgaa aaaaaacgat tacttctctg atttgttcat ctaatcgata
    33601 ctctttcttt tccagttgga tacgctggtt ttccagtttg ttcaatttta agatgttctc
    33661 tgttaattgt gaaagctgcg tgatactttc gataatccga tataaaaata tttggcgttc
    33721 ttcgtcagag agatttgggg cttgtaacaa ttgaacatat ccttggattg ttgctagtgg
    33781 tgttttgaat tcatgggata cactggacac aaagtcattc ctcagtgtct cgatactatt
    33841 gagttcttgg accataacgt tgaaatcttt atacagttgc tgtacttctg ctactttctg
    33901 ctgttcatcc attcgaatcg aaaaatctcc cgttgctacc agactcatat ttgtccctag
    33961 cgcactgatt ggatgcagga tacgccgccc aacaaaaatc gatattcctg tacccacgac
    34021 catactgaac cccgcaaaga cgaataacgg gtataacgtt ggttttccag ccgattcagc
    34081 aggcgagata gaatgtcgag acaataagaa aataaaaccg agaaaacaca gcagtgtcac
    34141 taagatcgaa atgaagacaa tactagcaaa atagatccat aattgtgaaa atagcttttt
    34201 tttcatcttt aaataaccgc cttatagcct agtccccgta ctgtgatgat ttgaaaatct
    34261 tccgtctttt caaaacgggt ccttaaacgt ttgatatgta catcgatcgt tcgttcttct
    34321 gtattcgtat ctaatcccca aatatcatcc atcaactgtt ggcgagtgaa gatcttgttg
    34381 ggataagaca gtaatttata cagaagcaga aattcttttt gaggcagaat caacgaatgc
    34441 tgatcttgta acactgtata agcatctagc tctaattttg tttgtccgat tatcaagcta
    34501 ctgctgtaat tgatctttga acgtcgaagc aatgcttcca cacgtaggat catctcattg
    34561 acatcgatgg gttttgtcat ataatcatct gctcctaatt tgaacccgcg tttcttatcc
    34621 tcaaaatcgg cctttgccgt aatcattaga acaggtgtgt caaatctggt gctacgtaat
    34681 gagtctagca agtcatagcc atccattttc ggcatcatga tatctgtaat gattaattct
    34741 atacgtgtcg cttctagttt tttcagcgca tcctctccat tcaatgcggt gatgactgaa
    34801 aagcccgctc gttccaacac agaacggtaa agcaactgta attgcggatc atcttctact
    34861 actaaaatac gattcattga tctccctctg ttttttgaaa aatttctaga ttttttcttg
    34921 tagttcatct tcagttaaca tttatttcgt atactacgat cattgttctg atatacttat
    34981 tagtataccg aatatttcaa tacgggagaa gggtgattat gcttcaatta aaagatataa
    35041 aaaaatatta taaagtcggc gaaaccacca ccaaagcatt ggatggtgtg tctgtcgctt
    35101 tcagacaaaa agaattcgta gcgattttag gtcctagtgg ttctggtaaa acgactatgc
    35161 tgaatgtgat tggtggacta gataattatg attccggtga tatggtaatc aacggaaagt
    35221 ctactaaaga ctttaaggac agtgactggg atgcctaccg aaacaactct atcggtttca
    35281 tttttcaaag ttacaacttg attggtcatc taggcattat tgaaaacgtt gaacttggga
    35341 tgacattaag tggtgtttct aaagacgaaa aacgaaaacg ggcagaagat gcattgcacc
    35401 gagtcggctt gacaaatcat atgcataaaa agccaaatca gttatctggt ggacaaatgc
    35461 agcgagtggc catcgctcga gcactagcca atgacccaga tatccttttg tgcgatgaac
    35521 caaccggagc gttagataca gaaacaagta tccagatcat ggaattgatc caagagttat
    35581 cgaaagaaaa attagtgatc atggtcacac ataatcctga actggcccat caatacgcag
    35641 atcgaatcat tgaattttct gatggtaaga tcttaacaga ttcccatcct cacatcgaac
    35701 gaccaaaaga tgatcaattt aacttacgca gaacaaagat gagtttttgg acagcgttaa
    35761 agctttcctt caacaatatc cgaacaaaaa aaggacgtac tttcttgacc tcctttgctt
    35821 ccagtattgg gatcatcgga atcgcgatcg ttctgtccct ttcttctgga ttccaaaaac
    35881 aaatcgataa cacgcaagct gaaacgatgg cgaaatttcc gattactatt tctaaggtaa
    35941 cgactaacca gactcgtgac gatgccggat tgggtgcaag caaagcggat tatccagaca
    36001 gcaaaacgat tactgcaaaa gtcagcgaag aagataaagc acagcacacg aataagattg
    36061 atcaaacata cgtcgattac gtaacagaca tcgatcctaa cttaagtaat aatatcggat
    36121 ttacccgtac tacaggaatc aatcttttac gtgatgtaaa tggcaaagta cagcctgtca
    36181 gcttctcgaa tcaaaatcct gatacggaat ctctttcttt atctagtacg atgtcagcaa
    36241 tgacaggtgt gggagtgtca agtttcccta cacagcttga cactagcaaa gaaaactttt
    36301 taaaagacaa ttattcttta cttgccggaa gttatccagc ctcagcaaca gatgtcgtgc
    36361 tgatcgtaga cggcaataat aatactaata tcaacgcatt gaagaatctt ggatttgatg
    36421 tgaaagaaga cgaaaaactt gattttgatg atatcgttgg tacaacattc aaattagtaa
    36481 acaacaatac ttactataca aaacttccaa ctgggaattt tatccctaat acagattatg
    36541 atgcgatgta tcagaatgct tctgatgaat tgaagatctc ggggatccta cgcgtgaaat
    36601 cttcttctac aatgaatctc ttatctccag gaatcgctta tagcgatcaa ttaacgactc
    36661 aaatcgtcaa cgaaaacaaa gaatcagaaa tcgtcaaagc tcaaagagac agtggtgtaa
    36721 atgtcttaac tactgaaaaa gttgacgaaa atgccaaaca aacattgctt agttatttag
    36781 gtggagacag cttgccttca agtatcatga tttatccgaa caattttgaa gacaaagaaa
    36841 agatcttgga ttatctagat gattacaata aaggcaaatc agatgaagat aaaatcattt
    36901 atactgattt agctggaacg atgactgaac tgactggcgg attgatggat gctatcactt
    36961 atgtccttat tgcttttgca gggatctctt tagtaacaag tatgatcatg atcagtatca
    37021 ttacttatac atctgtgatt gaacggacaa aagaaatcgg tgtactaaaa gctttaggtg
    37081 cacgtaaaaa agacatcact cgcgtatttg acgcagaaac gtgtatttta ggtatttctt
    37141 ctgggatatt aggtgtgttt attgcatggc tagctacgtt ccctatcaat agcatcttat
    37201 acaacatgac ggatctaaaa aatgttgctc aactaaatcc tgtccatgcg attattctag
    37261 tgatcgtctc tactatattg acgatgcttg gcggtcatct tcctgcacga atggcagcga
    37321 aaaaagacgc cgctatcgct ttgcgtgcag aataaggttg tgacaaccac atttagattt
    37381 gagtcataag agcgctgaaa tagtagaaaa cagcaagaaa cgaggaagta atatgttcct
    37441 tgtttcgcgc tgtttttttt aattattttt tataattctg gtatactttt ctttcctttg
    37501 taccacaact cttctggcgt atacctgtct tttccattta tgaatactgt tccatctgct
    37561 tcaatcgtta cttcagtccc aatccacata ttacgagaaa gtgcgagaag attttttctt
    37621 tttcctcttc ctttttttcc aaattgcaag gcatcggtta tctcttctgt ccaatgagat
    37681 ttcacgtatt ttacttctcc gttttcaaat gtaactttca aaatattcgc tatattttcc
    37741 acttttactg ctttaggaaa tgactcctcc atttttttca ctttccttcc tccaacacta
    37801 agtatgcgct ttcttttagt gataagtata tcatagttta ttctattatc aaaaaaacgc
    37861 atccattcca ttgtagaata ctttaccgaa caagttgaat tgttttcctc tttttcacct
    37921 tttactatag ataggtaaag acaactaagg aggaatctct catgacagat caaccgtatg
    37981 atttaagaaa agtcatcgaa gaactaaaaa cacttccagg tcaatatcac gaaacagata
    38041 ttgaaatcga tcctgaagca gaattatctg gtgtttaccg ttatatcggt gctggcggta
    38101 cagtaaaacg tccgactcaa gaaggaccaa ctatgacttt caacaatatc aaaggtttcc
    38161 ccggcacacg tgtgaacatc ggaacaatgg ctagtcgtaa acgtgtaggt gaaattttgc
    38221 accatgatta tcgaacactt ggtcgtttct tgaaagacgc tgtagaaaat ccaatcaaac
    38281 ctgtgaaagt agacaaagca gacgctccag cacaagaagt cgttcatcta gctaccgatg
    38341 cagacttcga tattcgcaac attttgcctg cacctacaaa tactcctgaa gatgctggtc
    38401 catacatcac aatgggtgta gtcttaggat cagatccaga aaaaacaatg agcgatgtaa
    38461 cgatccatcg tatggttcta gaagataaag atacgatcgg tatgtacatc atgcctggcg
    38521 gacgccacat tggtcacttc caaaaacaat tcgaagcctt gaataaacca atgcctatca
    38581 ctatcaatat tggtttagat ccagcaattg ccattggcac gactttcgaa ccacctacca
    38641 ctccacttgg ctacaatgaa ctatggtgtg caggagcttt gcgtaacgaa cctattcaaa
    38701 tcgttgatgg tatagcagtc gatgaagtgg gtattgctcg tgctgaattc atcattgaag
    38761 cagaaatcat gccaaatgaa acaatgcaag aagatatcaa cacgaactca ggaaaagcaa
    38821 tgccagaatt tcctggctat actggggatg ctaatccagc tgtacaagta gtgaaagtca
    38881 aagcagttac tcaccgaaaa gacaatccaa tcatgcaaac aacgattggt cccagtgaag
    38941 aacacgtatc tatggccggt attcctacag aagcaagtat tcttgccttg gtcgataaag
    39001 ctattccagg aaaagtagta aatgtctaca atcctcctgc aggtggtggt aaattgatga
    39061 ccatcatgca aatccgtaaa gaaaacgaag cggatgaagg tattcagcgt caagcagcta
    39121 ttcttgcttt atcagccttc aaagaattga agacagtcat tttagtcgat gaagatgttg
    39181 atattttcga catgaacgat gtagtttgga ctttcaacac tcgtttccaa ggagataaag
    39241 atatcatcgt gatcccagga atgaggaacc atccattgga cccatcagaa ttaccagaat
    39301 ataatcctgg ctctattcgt ttccgtggga taagtgcaaa aactatcttt gacggtacag
    39361 ttcctttcga tatgaaagaa cattttgtac gtgcaaaatt ccaagaagta gaagattggg
    39421 aaaaatattt gaaataatga atgatctgca actgttttga catcataaaa aggagtgcgg
    39481 aaaatggaac aattggcaca acggaagaaa aaaatcgtga ttggtgtaag tggcgcttca
    39541 ggcaccattt atgccatcaa cctagtgaag aaactaaaag aatatccgat gatagaaaca
    39601 cacggaatca tcagtccatg ggcaaaacag aacttaaagc tggaatccga cttatcacta
    39661 actgaattcg aaagcctgtt tgattaccat tattcaaaca aagatttagg tgctgctgtc
    39721 gccagcggat catttttgac cgatggaatg atcatcgtac cggcaagcat gaaaacagtc
    39781 gcaggtatct ctgttggttt aggcgacaac ctgattgcac gtgctgctga tgtaacaatg
    39841 aaggagcaac gaaagttagt cattgttcct cgtgaaacgc cattaaatgc cattcacttg
    39901 gaaaacttga ctaaattagc acgactaggt gtgcaaatca taccaccaat tcctgctttt
    39961 tataatcagc ctcaaacgat ccaagatctt gttaatcacc atacaatgaa acttttggat
    40021 caatttgaaa ttgtaaatga gcattcaaaa cgttggcagg gtgattaata tggaaaaaga
    40081 aacgatagtt gaagtaacca aactaggttt cacgatccaa gctgctgtta aagtaatcgg
    40141 taaagactta ttgatcactt taacaggcgg agatacacca catatcggaa cagtcactac
    40201 attttctcgt gatacagaga tgcaaactgt acgtttccct agccacgatg gtcggttcca
    40261 taaagacgat gtcttagccg aaaaaatagc tgtgatcatc aaaactgccg ttccgggaag
    40321 ttgtacgatc acttccggta tccatgttga ccatatctcc aatgcacaaa tcaacgcctc
    40381 ttttccgatg tcagaagagt taggttacaa gattttagat tggttggaaa aaatagattt
    40441 ccatatcaaa gaaccagttt attataaaga tggtgaaaaa ccattatgaa agaagaggtt
    40501 gtgaaatcag cgttatgacc tgagtatgag agaaaaaaat ggaaaaatag cttctcatat
    40561 tttgccgttt ttgagctaat accgagggac agctgattga acgccgttta tcaagaggtt
    40621 gtgataaagc cgcttcgttt cgagtagtaa gaaaaatttt gtaaacatgg gtttccacat
    40681 ttttgcataa atttgactta ctaccgagaa actggctttt gaacaccgtt tatcaagagg
    40741 ttgtgacacg tcttttgtca caacctcttt tatttttgct tcactgtaac tgctacaata
    40801 tcaccgattt cttttccgat gtttttacga atatcttttc gtagtccaag gatgtagcag
    40861 actgaaccat ctggattttt cacgcccata ttcacgatac tgccttcata tggcacattg
    40921 tcaaaagttg cttggacttt aactcttcca gcaccgaatt cttttcttat atcatacgga
    40981 aaaataatat atgccccgcc cttgccgact tcggaagcat agatttttga ttcaaaagaa
    41041 taaatttccc tcattttatt tctcctattt tttacatcta gtatagcata gcaaaaaaaa
    41101 gaaggaactg tgacaaaagt cttgtcgcag ttcctttttt cgaataaacg gtgttctcct
    41161 gccaactcct cggtcacaag tcacaatagt caacaaacat gagaagctgt tttttgaaat
    41221 tgctccttgt gactcagagt taaacggcag gctcacaacc tcttccttaa acggtgttca
    41281 aaagcttgca tctacggcac taagcccaat cagatgaaaa atatggagtg ctatttttat
    41341 ctgattgttc ttactgcttg atgcagagca gctttttcac aacctcctac atggtgttca
    41401 aaatattatt cgccttttgc ttctttcact aattttgcga atgcttgttg ttggaattca
    41461 gcagctaagg ctttcgtacg ttgttcttgc tctgctttgc tcatttttgg attttcagtc
    41521 attgctttta ccataccgtc ttgaacataa gcttttgctt cactttccat cgtactttgc
    41581 tgtttcttca ctaattcagc taacttggct gcttggtccg tacttaattc tacccatgtc
    41641 tctgggattt tgaatgtatt cactcggctg tcatattcgt gattgttatc agcaatattg
    41701 aaccagaatt tatacatgtc gtttttgtat tcccaataag tagttttcgt cactttttca
    41761 gcatcgccgt ctgtcttttc tactttattt gtttcgttat ccgtaccagt tgcttttggt
    41821 ttttcttgtt tttcatttgt tcggtaaaga tacacttttt cttttccatt ccctaaagct
    41881 ttatacaaaa gcatatctgc tccttgggaa tcagcactgg aaacaatttt ttctgttttt
    41941 gtttccgtta ctttttccat tccaaagtga ttggacaaat tagcgacgat caaacttagt
    42001 gaagcgacga agattagtcc gaaaatcaaa gataaaaagg tttgccatgt ttttttagcg
    42061 aacacgttcg ttaaagcaaa agcaagcaag ctgacaatca aaactccaat aatcatgcat
    42121 tatcccccgc tttcattaga acaggttctt ttttcttcaa taaaaaggca ataataaagc
    42181 caagaatccc aaagatgatc gctacgataa acgcggcatg gtaacctgac agtgtggcat
    42241 tgattgcctg atctttataa gctaatggcg tattatccaa tacagatttg cttgggatat
    42301 ttgcttttgt cacattcgtc aacacactga tcaaaatagc tgtaccaatc gagcttgcga
    42361 tttgacggaa tgtattattt accgctgtcc catgactgat caagttattt ggcaatgcat
    42421 tcataccaga agtcgttacc ggcatcatga ccatggagat cccaaacata cggatcgcat
    42481 aaaggatcac gatatataaa actggagtcg tttttgtcaa gaaagcaaat ggtgcagttg
    42541 ccgctgtcaa aatgaacatc cctgtgatgg ctaaacgttt cgcgccgtat ttatcgaaaa
    42601 tcgcacccgt cacaggcatc atagccccca tgatcaatgc acccggcaac aacatcaagc
    42661 cagaatggaa tgctgattct ccacgaatat tttgaatata caatggtacg accatttctg
    42721 cccctaccat cgccatattt gttacaccag ctaaaacagc tgcaatcgtg aatgtagatg
    42781 atttgaatac acgaagttcc aagaatggat gttccaaatg taattgacgc catgagaaca
    42841 aggcgatgaa aatcacacca acaactaaga aaccaattac tttcaagctt ccccagccgt
    42901 catctcctac actagaaaat ccgtaaagta aactaccgaa tccaatcgtt gataaaatag
    42961 cggataaaat atcaatgcta ggatttgaca atggaataac acttttcatt aggaagaatg
    43021 ctaaaaccaa gacaagaaca acgattggca gtaccatacc aaacaagtca cgccaatggt
    43081 agttatcaat gatataacca gataatgtag ggcctaaagc aggagcaagt ccaataacga
    43141 tccctgacat ccccattgct gatcctcttt tttctggcgg gaaaatagat agcatgatat
    43201 tttgcaataa tggcatcgat actcccacac cgcaagcttg gatcaaacga ccgattagta
    43261 atgtactaaa attaggtgct gtaaagcaag taatcgttcc gatcaaaaag atcgtcatgg
    43321 cagaaagata taaatttctt gaactgaatt tattgatcag ccatgctgtt attgggatca
    43381 tgatcccgtt gactagcaag aaaccagtcg ttaaccattg cacatcagac gctgaaatat
    43441 cgaaagcttt catcaatgta ggaaaagctg tcgtcaataa ggtctgattc aaaacggtac
    43501 aaaatgtacc aattaataag acaacaacta aaagtgtccg attatatggt tttccgtaaa
    43561 tatctacggg ttggttgtta ctcatatttc tccttctttc tgaatttttt ctgaaactac
    43621 tagaatactt tagtcctaaa ttcgctattt gtcaacctac ttgacacata agttaatacg
    43681 gatataatta agggaagcaa gaggacaaaa ggagtgacaa aaatggttgg ggcttccctt
    43741 aaacgtttgt tggaaaatga tcaattggtt gttggcatca gtgaattaag tgatatcgta
    43801 ggtgtgtctc cacgtcaatt aaggtattgg gaacaaaagg gattcattcg ttcgatcgaa
    43861 gctgatgcga attgtcctag aaaatatcgt ttacctacag tcataaaagt agaactgatc
    43921 aaaaaatatt tagatgacgg atttactttg tcaaaagctg cagaaaaggc agaaatccgc
    43981 caaaagaaaa tgcaccatgt ccgtaaagtt ttttcaaaag caatcaaaga tatcgaattg
    44041 atcgacgaac gctatacgat tttacaaatc ggtaacttca aagaagagaa tgctaagatg
    44101 tacatcattc atgacaacga gacagacgaa ttaacttaca agctccttcc tgtcgatgaa
    44161 aaagctgact acgaacagtt gttaaaagaa ctctaaacgc cactaatctc ctaagtacca
    44221 agctttttaa taagtagatg ctacataaat acttgaaaaa aggcctgttt gaacataaga
    44281 atatccgaac ggtgatctgc gtttctttca tatagaaagg aattctccat cactgttcgg
    44341 atattttttt atttttttcg gttactttct tctaatacat ctgttagcca atttgcatat
    44401 tctgtttccc gattgatcgc atgcgctaaa atcaggtagt gtccgtaatt ttcatgtttt
    44461 tctttttcag taggaaagat cgtttttttt cgctctaata gatgaagtcg tttttcttca
    44521 tgaaggtcac gctgctgctg aataatttct actaatgccg gatcattcac gtctttgacg
    44581 aaatacaatt tcagaacaaa ttcgtctcga ttaaccggta gttcattggt gggtgtatga
    44641 atccactctg ccaattgttc cttcccttct tctgttaatt cataaacttt cttttccaat
    44701 ttttcacctg tgatctctac ttgatgctga atgattcctt gctcttccat ttttgcaagt
    44761 tcaggataaa tctgactatg ttttgcttgc caaaattctc ctatttcatt tttgaacgat
    44821 tgattcaatt catatcctgt catcttcttc ttacttaata accctaacaa aatatatcga
    44881 agtgtatttt ttcttgccat cagttttccc tccttgacaa atctttaaat ccattctatc
    44941 ataaatgagt aatcgaaaac atgtagttta ttacatgttt taatttataa ggagatgctt
    45001 aaacatgaaa gaatttaaag aattggaaga ttttattgga actcacttta tctatacgta
    45061 tgacaatggt tgggaatatg aatggtatgc caaaaatgac catactgttg attaccgtat
    45121 ccatggcgga atggtcaaag gccgttgggt aaaagaccaa gaagctgata tcgttaaatt
    45181 gacggacggc gtattcaaaa tcacttggac agagccaaca gggacagacg tggcattgga
    45241 ctttatgcca aatgaaaaga aacttcacgg aatgatcttt ttccctaaat gggttgaaga
    45301 acatccagaa atcactgtta ctttccaaaa cgaacatatc gcagaaatgg aagcagctcg
    45361 tgaaaaatat gaaacttatc caaaattact tgttcctgaa tttgctacga tcacttatat
    45421 gggtgatgca ggtatagaca atgaagatgt tattagcgaa gaaccatacg atggaatgcc
    45481 agatgatatc cgtagcggaa aatacttcga tgaaaattat aaacgagtaa aataaggttg
    45541 tgaaagagag gttgtgaaat cagcgttctg acctgagtat tagagaaaga aacggaaaaa
    45601 tagttcctca tgttttgccg ttttttgagc taataccgag ggtcagctga ttgaacaccg
    45661 tttatcaaga ggttgtgaaa tcagcgttat gctttgagta ataagaacgc tagttagaaa
    45721 atagcttttc atattttcta ggctagtggg cttattaccg agaagcagcc gtttgaacac
    45781 cgtttatcaa gaggttgtga aatcagcgtt ttgacctgag tattagagaa acaaatggaa
    45841 aaatagttcc tcatattttg ccgttttttg agctaatacc gagggtcagc tgattgaaca
    45901 ccgtttatca aagattgtaa caactgcata ttcacacagt taaattagtg acttcaaaat
    45961 gaaataatgc tcccagcaaa aaattaggct gggagcatta tttcgttatt ctgttcatca
    46021 aaaatcagcg ttttgattcc atttcatcac aagttcctcc tcatttactg cttcatcttt
    46081 ttgctgtgtt tgaattgtaa aaccttgtga aagatagaaa tgaatagctg attgattttt
    46141 ttgatagact gtcaaagtca gtgttttatt ggtttctttt atttttttca ttagttgcgt
    46201 accgattctt tgttgccggt attccctttt cacaaagatt cctgcgataa actgatcaat
    46261 caccccagca aaaccaataa tttcttgatc tatttctgct aagtaaatca ctgcatctgg
    46321 taaagctttc ctaacagatt ctacttgatt ctcccaataa gttgatggaa tgaattcatg
    46381 agaatccaag ttagcatgca gccaaatcga tagaacagat tccagttctt tggcagacaa
    46441 ttttgttgtt gtgcggatca ttttttctct ccttacttat tcattgattt taaaataaaa
    46501 accatttttt tgaagctctt ttacaagttt tcgcccctca aaaaagtata tcttctcttg
    46561 ttttactttt ctaataccaa aagaaacagc aactttagga tcatcagctg aaacgattcg
    46621 ataagttcca ccaggcaatt gatccagctt gactttccca tgatggtcgc tttgtactga
    46681 aaacggcaca ccatttctag taagtgtttt tttcttatgt ttcaaaatga atgaactacc
    46741 atttaccggt ttccctgacg aatcactaat aataaatgaa aaatcaagca cttttttact
    46801 taatctatac tgatagatta gtcgtccgat aaacactaac agtatgacta cagctattat
    46861 cgttcctgca agaataaacc attgccgcat ggttctttcc tgatttcctt ttccttcttc
    46921 tttttttacc gattcgttat aaggaatccg atgtcctgtc actagcaaac gatgcgtgtt
    46981 gatcatatac ggcgtacatg taagcaaggt aactaagtct tctccttctg aaatcgttag
    47041 aacagacgtg tcatctggca gtaccacttg tatattttta acttgataag ccaatttctc
    47101 ccccaaaaca gtcaaaataa acgtgtctcc gttttctaaa cgatctaatt cggtaaataa
    47161 ccgtcgatta ggtaaaccgc tgtgagcaga gatcactgaa tgcgtcgaat ttccaccaag
    47221 cgggaaagag gttccttgca agacgcctgc tccattttca aggatcctac cattgagccg
    47281 atcataaagt gaaatattta attggatctt aggtatattg atacttccga tcagccattc
    47341 ctctaattgg ctggatgttg tactttcatt tctgttcttt tcattgaaag gatcagtacc
    47401 aggattgaat ccttggtcag ttaatcgttg gtttttctcc tccattttct ttcgctgcac
    47461 ttcaatttca gctgcggtcc gtttttgtac ttgttcgata cgtttttgat caataaaact
    47521 atttaaagaa tccacataaa atggatataa agcgatcagt aaccctacga cgatacatat
    47581 taataaaaac aaacgaaaca aaagtcgacg agactgtttt tgcttactct gcttcacatg
    47641 tgtcctccct tgcaagtttt tttgttcttt cttttattat atgggttcag gaaaaaaata
    47701 gaaaatgaaa gccgatgagg ttgtgaaaaa gctgtcctgc atcaagtaat aagtacagcc
    47761 caaaaaaata gctactcata ttttttgttg ggttgggctt attaccgcag atgcaagctt
    47821 ttgaacaccg tttaaggaag aggttgtgaa aactgcgtta tgctttgagt aataagagcg
    47881 ctagtcagaa aatagcttct catattttct aggctagtga gcttattacc gagaagcagc
    47941 tgattgaaca ccgtttaccg agaggtcatg aaaaagctac tttgtttcga gtattaagaa
    48001 aaattctgtt tcaaaacaag gagatgcaac aaaacttatg tcgcatcctc tctccttaga
    48061 actttcactt atgtttttct tgtaaaattc ataaatattt tcatgaattt tctaatttct
    48121 tgcctacctc tcgcatagga tatatgatga atttatctaa agtttgcaaa ggagttcgac
    48181 aattgaaaaa atatggccca tttttagcaa tttttttcat tgctttggca tttctcatgc
    48241 ctcatttatt cacacataaa ctaattttgg gtgctgatgc cccattccat tacaatcggt
    48301 tctatgatgc cgcgcaacaa attaaatatg gggatttcca ttattttcct tccctttatg
    48361 gattccagca aagtggcagg atcgtgaatg ccgtttacgg cccatttttc gcttatttac
    48421 aaggattgat cgtgttgctt gcaggtagct ggtttcatta tcagattctt tcaaatttca
    48481 ttctttatct tatttcagga ttttctatgc tgattttact gagatatgtc aatgttcgaa
    48541 attgggtaag tgtaccagta gccgttttat tcatgagtac gtattctatt caatactggt
    48601 ctatcaacca aggattcact agctggggga cttgttttta tcctttatgt atgatcccta
    48661 ttgctgattt cgtccttcat aaaaagttcc ctgttatcaa agtcgctgtc tcagtgggac
    48721 ttatgacaca gatccattta ctgtcttcga tcatgttagc tttgatgtat atcccttttt
    48781 atctttatta cttttttaac cagactgaaa aaggaaaagc actgcttcaa ctgattaagt
    48841 cggtcttgct ttattttgtt ctgacagcaa atatttgggc aggattagct attgtttaca
    48901 gtgggaataa gattcttcct ccctttgtta acagagaaat gagtcaaaag gcgatagatc
    48961 tggatggcag ttattggctc cattacccta aggcctttcc tatattgata ttatcaggtt
    49021 ttttgctttt tattttcttt caacaaaaga acaccttatt ccaaaaaatc gtgttgtaca
    49081 caagtcttgt tttctttttt ctttctacta gcttgattcc atggacgaca ttgatcgaaa
    49141 aaaatgtgcc ttttattagt ttgatccagt ttccatttcg atttttcgtg ccatttacgc
    49201 tattgcttct actttacctt gccctttcac tgaaccagtg gtctgaacaa aagtggttcc
    49261 gtcttttaag tatatttggc attcttattt tttcagcaca gacgatccag aacttatacc
    49321 agcatctgga aaagtgggaa aatgaaacat ttgtcagtcg acatacttat ctattcgata
    49381 cgccggaaga agcaaggaaa acattcttca gcaaagatat gtctaccagc ttgttcgttt
    49441 tccaaaaaac cacacctgac tatctgccaa tctataagga gacaaaagac aataaatacg
    49501 accggtataa cgaagaaata ctagaaaacg aaacaacttt tataaaaaca catccaggcg
    49561 gtcttttgac aatcaagtgg aaaaacactg gggacaaaac tgttcatatc cctgttatcg
    49621 tctacgatcg gactgtgcta cagcaaaatg gaaaaacatt gactgattat gaagtaacag
    49681 atatcgggac cccaatcgtg aagcagcaaa aaggaatcaa cgagctcacg cttcattatc
    49741 aaacgccaat ctatttctat ttcattcttt ctcttacttt gattggctgg tttaccttgc
    49801 tatgtttatt tatttatcat agatacaagc ttttacgtgc ttaggcaaaa gggataaata
    49861 catccgatca aaaaactctc caaacggtat aatcgtttgg agagttttat tttaatcagt
    49921 ttttttatgt tatatgttat attttttatt cgttcacatc taattcgatt tccaccccgt
    49981 agtgatcact gatgattgga ctatcgatcc catcaaaaat ccgttgatat tttttaacct
    50041 gcattccttc agggacgaaa ataaaatcta tacgcaattt ttctgtattt tgttcccaac
    50101 catctatttt cttttccaca gtagctgctt ttcctttttc attcgcgaca acatacgaat
    50161 cttgaagaag aaggcaactt tctcttacag tataataacc ttgagagtct actggattat
    50221 tgaaatcacc taggaaaaaa agtggtacgc gagtttccaa aaagtagttt tccaagtttt
    50281 tccactcaaa ataaaagcca ctttttttat ctgtccacca agaaaagtgg cagctcgaga
    50341 caaaaatgtc ctgatcatct atctttgttt tcccaatcaa gatcttgcgt gtctgataat
    50401 cttctttctt ttgaaattgg gagacggtaa ggacctgact ttccaatgtt tttttcgtaa
    50461 gcagtgcatt tccttcttca tatttatcat aaccgatgtg gctcatttcc caactccaaa
    50521 aatactcttt tccgtgttcc tttaaaagct gaactaaacg gtaggcaaaa ttatctttac
    50581 ggataggtac ttgattcttt accggacaga acttcattag cttcgcaggt tctacttctt
    50641 cagattccag taattggttg atttcttgta aagcaatcac ttcataatct tctaacagga
    50701 tcttatctgc taattcttgc aattttttct ctggttctgg ctcaagccag ctatgcgtgt
    50761 tgagtgtcat gaatttcatt ggttttctcc ttgtcttcat ttcgaaacaa aagggttgtg
    50821 acaaaatttt tgtcacaacc tctccagcaa atagtgttct cctgctaact cctcagtaat
    50881 aagctcaatg gaccaggagc tattttttgt ttggctgttt ttatcacttg gtgcagggca
    50941 gctttttcac gacctctcca ctaaacagta ttcaaactgc tgcttctcgg taataagccc
    51001 aaccaaacga aaaataggag gagctatttt tgtttggctg ttcttatgac ttgatgcagg
    51061 acagcttttt cacaacctct ccttacattt taatggagcc gatcacttta ccagctgtca
    51121 ctgtacctaa ttgcttgatc actacttctt ctactttatc gtttgtaaat acgatcatga
    51181 tcgttggatc tttttcttcg ttttggatca catcaagatc catctcagct aatttcgttc
    51241 ctgttcctac ttcttggcct tctttgacag caatctcaaa agctggctga ttcatttgga
    51301 ctgtatcgat tcccatatgg atcaaaactt cgataccatc tttcgtttcc agcccaattg
    51361 catgtttgct agggaaaata cttgtcactt ttccagcgat cggcgcaaca acttctcttg
    51421 atgttggaat aacagcaaag ccgtcaccca tcattttttg tgagaatacc ggatctttta
    51481 cttcagataa aggaatcact tctccagaag ctgcggaaac tagttcttgt tctataccta
    51541 agtattgctt actacctgct tgtccatttc ctgtagaaac catttctggc tctggaatct
    51601 ctgctcctga ttgcagcaga tcttcgatat ctgatttcaa gacatctgct tttggtccat
    51661 aaactgcttg gactccattg tctttgacga tcaatcccat cgcccctgct cgtttccagg
    51721 cttcttcagt ccctactttt tctcgatcat ttacacttac gcgtaaccga gtcatacaag
    51781 catcgacatc tttgatattt tcttttcctc ccagcaaatg aatgatctgg accacttgct
    51841 gatctgctgt tcctgttccg ctgttagata caacggtttc ttcactgtca ttgtcgtaat
    51901 ttccgttacg tcccggtgta gcaaagttga attttttgat caagaaattt gctaagaaat
    51961 acgtaacaac accaaaagcg atcacacaca acacgaagtt gataagatct ccacctagac
    52021 ccgctttgat agctaacggt gtccgagtca gcaattcgat attcccaaat gaatggaccc
    52081 gcaatggcaa gatatctgcc atcgcaaatg cagccccttg gatcactgaa taaatgacat
    52141 ataatggcac agcagcaaac ataaacatga actccaatgg ttctgttaca cctgttagaa
    52201 agacagccaa cgctgctgaa aaatacattg atttatatct tgctttctta tcaggatcga
    52261 cattacgata catcgcaaaa gccattccca tcaagatacc tgaagaacca atcatttgtc
    52321 ctactttgaa acgagccggc gtccagttat gcaacacaaa ctcatattgc gacatatccc
    52381 ctgcaccttt aagattcact aaatcagtgg cccaagccaa ccataacgga tcttgcccaa
    52441 atacttgtgt ccccgcctgt gcgcctgata aaatctcata cgatccgcca agctgtgtat
    52501 agttgatagg aatcgtcagc atatgatgca atccaaatgg caatagtaaa cgttctaatg
    52561 ttccaaataa aaacggtgct agaatcggtg cgctttcttg tgattctgca atccataaac
    52621 caaaattatt gattccagcc tgtacgtttg gccacaccac agcaagaatc aatgccacga
    52681 ttgttgacca taagataaca acaaacggaa caaagcgctt tccattgaaa aatgacaaag
    52741 catccggcaa ttttctataa ttatagtact tattataagc cattgccccg acaaatccag
    52801 cgatgatccc tacgaatact cccatattca aagctggtgc ttccaataca cttgtaaaaa
    52861 atcctttaac catgatcttc gtaccgaaca gagtgtgggt aaatgcatct tcattcgcaa
    52921 gcatgtcact tgtgacacca aagatagccc cagtgatccg attgattaaa ataaatgaga
    52981 tcccagctgc aaatgctccg cctgctcttt cttttgccca acttcctcct attgctaaag
    53041 caaataaaat atgaagatta ccaataattg cccaaccaat attttcaatt actccgcccg
    53101 ttgtgacaag cggcgtccaa tcaggattga tcaagggaat tgatttccct atactgatca
    53161 tcaacccagc tgccggcata actgctacca caaccattaa agcctttcca aatttttgcc
    53221 aaaactcaaa actaaatatc tttttcattc cgtttagctc ctttacgcaa tcggtttcgt
    53281 taaacgtatt atagcgtgcg ttttcttttt tgtaaatgct ttatttttta tttttctgtc
    53341 tataccattc tataaaacct ataatacgtg tgttcccttc tataattttc tcctaaaaat
    53401 ttattttttt aagctttttt ctatgaaata ttttcttttg tctattgact tgtgcaatcg
    53461 gttgcgttta ttatgaacgt ataaaacagc tcattaggag gagaaaaatg aaacagatca
    53521 aacgactatt tgctattgat ccatggaaaa tcagcacgac acaattagat aaaaaaaatc
    53581 ttcgactgca agaatcttta acaagtattg gaaacggtta tatggggatg cgcgggaact
    53641 ttgaagaaac ttactcaggg gaccaccatc aaggtactta tttggcgggt gtctggtatc
    53701 ccgataagac acgtgtcggc tggtggaaaa atggttatcc agaatacttt ggaaaagtga
    53761 tcaacgcctt gaactttatc gcgatagata tttcgatcaa cgatcagctg atcgacttgg
    53821 cttctttgga accagaagac ttttactggg aattagatat gaaaaatggt gtattatctc
    53881 gtacattcac aatcactact tctactaata aagtacgcat ttccttcgaa cgttttctga
    53941 gcattgtcaa aaaagaatca gcttatatct atttaactat agaaatgctt gaaggtagcg
    54001 gaacagtcaa actcgtatca aaattggatg gaaatgttca aaacgaagac agcaactatg
    54061 atgaacattt ttggaatgag attgatcgtg gaactataga agaaatcggc tatttgacga
    54121 ctaaaactat tccaaacaac tttgggattg aacaatttac tgttactgca gcaatgcgcc
    54181 atttcgttaa tggaaaatca gtcatccctg actatcacga agatacttta gcattacatg
    54241 gttgcttgtc tgcagaatta tctcaaggtg agacatggtc agtggaaaaa gaaattatcg
    54301 ttcttactag tagagatatt ccagaagcgc agcaagcaga aaaagctgtc tcagaattaa
    54361 cgaaccagac aaacaattat atccaagcaa aagaagagca aacagcggct tgggcagaac
    54421 gatggaagct tgccgatgtg gtcatcgaag gagacgaaga agcacaacaa ggtattcgat
    54481 tcaatttgtt ccaactattc tctacttact acggcgaaga tgaacgattg aatatcggcc
    54541 ccaaaggatt cacaggagaa aaatacggcg gagccactta ctgggataca gaagcgtatg
    54601 ctgtccctct ttatcttgct ttagccaaac ctgaagtaac taagaatctg ctgaaatatc
    54661 ggcataatca actgccgcaa gcaatccaca acgctcagca acaaggatta aaaggcgcgc
    54721 tttatcctat ggtcaccttc actggtgtcg aatgccataa cgagtgggaa atcacattcg
    54781 aggagattca ccgaaatggc gcgattgcct atgcaatcta caattatacg aattacaccg
    54841 gcgatacgga atatttgaaa aatgaaggac tggaagtttt agcagaaatc gcacgcttct
    54901 gggcagaccg tgtccatttt tcaaaacgag caaataaata catgatccac ggtgtgaccg
    54961 gcccaaacga atatgagaac aatatcaata acaattggta tacaaatacg atcgcagctt
    55021 gggtcttgcg ttacacgcga gaaaattatt taacttatca aaaagaagct gctatcacta
    55081 tcagcgaaga agaactagcc aaatggaaag atatcgcaga gaacatgtac ttcccagttg
    55141 acgaagaatt aggaatcttt gtccagcatg acacattctt agataaagat ctcatgcctg
    55201 tatccgatat tcccacaagc gatcttcctc tgaatcagca ttggtcttgg gacaaaatcc
    55261 ttagatcttg cttcatcaag caggcagatg tactacaggg gatttatttc ttcaatgata
    55321 cttttacaaa agaagaaaag caaaaaaact ttgatttcta tgaaccaatg actgtccatg
    55381 agtcttccct ttcgccaagt atccattcga ttttagcagc agaattagga atggaaagca
    55441 aagctgtaga aatgtaccag cgaacagctc gcttggattt ggataattac aataacgaca
    55501 cagaagacgg cttgcacatc acttccatga ctggtagctg gttgtcgatt gtccaaggat
    55561 ttgctcaaat gaaaactgcc catgatcagt tgagattcgc accatttctg ccaaaaactt
    55621 ggaaagctta ttctttccat atcaattatc gcggacgttt attgttcatc tcagtcacag
    55681 atgaacaagt tactttcaag ttattagaag gttctcctct agaaatttac gtctatgaac
    55741 agtcttattc tttagcggat cgtctagaaa taacgctaag aaaggaggaa gcaaatgttt
    55801 aaaggggtat tgtttgattt agacggtgtc attaccgata ctgctgaatt ccattatcgt
    55861 gcttggcgaa agcttggtca ggaaatcggc attacgatcg accacacatt caacgaacag
    55921 ctaaaaggcg tcagccgaga agactcactc tctttgcttt tagcttatgg cggaaaagaa
    55981 cactctttta caaaggaaga atttgcagaa ttagcgaaaa gaaaaaacga ttattattta
    56041 gagatgatcc agacgatcga accaaaagat gtcttccccg gggtcgtgcc tttactggat
    56101 tctttaaaag aagaaaaaat caagattgct cttgcttctg caagtaaaaa cgggccattc
    56161 ctacttgaaa aaatgggtct tacaccttac tttgatgcta ttgccgaccc ggcagaagca
    56221 acaaacggaa aacctgcgcc agatatcttc ctccttgcag caaaagctgt cggactaaaa
    56281 gcagaagaat gtatcgggat cgaagacgcg caagccggta tccaagccat cctctcaagt
    56341 ggcgctcaac caattggcgt gggacgtgct gaagaccttg gagaggagat cccgcttgtc
    56401 cctgatacga cttttcttac gatcgattac ttgaaagaaa agtggcatga ccatggataa
    56461 tccagagatc tccgtcgtac cagttccaga gactgaaata aagaaaatca cattgaagaa
    56521 cgactactta gaagtcgttc ttctcaatta cggtgcccgc ctgcaccaaa tcttcgcacc
    56581 agacaaagaa ggaaaatcag aaaatgtttt attgtcttac gatcgtttcg aagatgttct
    56641 aacagacaaa agcttttttg gagcaactgt cggacctgta gccggaagga tccgggatgc
    56701 ttcttggggt gagcatagat tggagaaaaa ctgcggatca caccatatcc acggtggcac
    56761 gaaaggctgg tctttccaat tttgggaagt agaagttttc aaaactccat catcaatagg
    56821 tgtggtcttt tacttaaaag atgaattttc tacctatcca ggaccaatca ctgctacgat
    56881 cacttaccgt ttaacaaaaa acgaattaga gatgacaacc tctgctagta gccttgttga
    56941 aaccatctgc aatccgacca accatgccta cttcaacctt tcaggaaatg gaacaagaga
    57001 catctatgaa catcagttaa cggtcttttt agatggtgtg cttgaattag atcaagaaaa
    57061 actgcctact ggaaattgga caaaaaaaga aaaactgcca atcgacttta gaaaatcccc
    57121 aacactgcaa gagatccttg catgttatcc agatggacta gatgatgtat ttcttttgca
    57181 tcatcctagg ctttccaaaa cttccttaca attattcgag aagcattctg gtcgccaaat
    57241 gactatagca acttctaata aaagtatggt attattttct acgactggat tcgaagctga
    57301 tttctctgtc aatggaaaac agatgcattc aaactacgga ttagcaatcg aaccgcaaga
    57361 aatccctgat atcgttcatt tccccaaatt tggatcgatc aacctccatc ctggtcaaga
    57421 acggatcagt cagacgattt atcggttctc tgcacaataa caagagaaag gtgtttttat
    57481 catggctatt accgtaaaag atgtggcgaa aaaagccggt gttgccacct cgaccgtctc
    57541 tcgtgtcatc aacgatcatc ctagtatttc cgagacaaca aagaagaaag tccgaaaaat
    57601 tatggatgaa ctaggttatg ttcctaacat gactgcccgc aatctaggaa aacgcatttc
    57661 cagtgccatc ggcgtaatct taccccctct tgattcaaaa gagcggatcg gtaacccatt
    57721 ttatcttgag atcatggaag caatcaacga agaagcgcgg aattatgata tgactacagc
    57781 aatcgctact gctaaaaatt ttgaattgct gttagagaac gtccagcgta tgcatttaca
    57841 aaaacaagta gatggtttta ttctagtgta ttcagatagt caagatactg tcattgatta
    57901 tttataccaa aaccacatcc ctttcacttt gatcggacag ccttatcatc atgagaacga
    57961 aatcgtttat gtagataatg ataaccagct tctaggtaaa caagcaacag aatttttgat
    58021 ccagaatgga cataagaata tcctgtttgt gacaaacacg actcatgaaa gtttgtattt
    58081 cgaacgatat ttcggttatc aaaaagcaat gatgatggct ggtcttcctg cgttatccag
    58141 tgtagtacta gagcatccgg aggattatct gtcctttgag aaaacgttga aagaaaacga
    58201 agccacagca ttggtggtca ttgacgatat cttcgccctt cgcacgatgc agttggcgca
    58261 aatgtatggc tatgtcattc cagagacact ctccgtcatt agcttcaaca actcgatctt
    58321 ctcaacatta acacaccctt accttacaag tatcgatatc gatatctccg aattaggacg
    58381 tgtcgctatg caaaagctgc gcgaattgat ccatgaagaa ttgagcagtg gcgtacgttt
    58441 ggtcatccct catcgcttga tcaaaagaga gacagtcgtt cctttagaaa acccatacta
    58501 aatagctgac tcactaaata cgctgaccat ttatcctatg gtcagctttt tatgtaaaag
    58561 aagatactac ttctaacaca ttgtttatct gtaaaaaaga gcgtgggaca aaagtaaaga
    58621 acacttttgt ctcacgctct aaacacgtat aaacggcgga agcagaagca actccttcgg
    58681 aaataagctg aaattcacaa aaatttaaaa agcaattttc ttgagtttct tcttatttct
    58741 tggagttaaa cgcttctgtc ccagcctctt ttttccttcc ttcaattttt tacacgtcga
    58801 cgattcaata aaaaaccgcc taatattgta aagacaggtg caagaatcga gaaaaaggcg
    58861 aatggcaagt aatgcaacgc gctaactttc atcgttccca taatgaatgt gccgctgact
    58921 ccccacggta cgagagaatt gacggtcgca cctgaatccg ctagtgttcg tgtcaaatag
    58981 gtttttgata agccaacgtc atcaaaagaa cgcttgaatg tttctcctgg aagaatgatg
    59041 gacagatact gttctccaac gatcagattg attccgatac agctcaaggc agtaaacccg
    59101 actaaacgag aaggtcggtc catcttttct tttaattctt gaacgatggt atcaacgatc
    59161 agatatttga tcagtaaccc acctaatgcc aatgcaagta aaatcaaact agcagaacct
    59221 aacatactca tgatcccgcc tcgagaaagc agttcatcta gctttggatc aggtgtattt
    59281 gcgacataac cattcatcaa gatgtctgct gcttttccga ccgtcaaact tttctcatgg
    59341 ataaaagaaa gaacgagagc agctgtcgat cccgctagta atgtagggat agccggaatt
    59401 tttttgattg ccccccccaa ataaaataac tagtggaatc aatgtccaag gagagatcca
    59461 aaagctcgct ttcatgtttt ggatcatttc attgatacta gctagatcgg ctgaatgact
    59521 gttatgtcct aatatcgtat aaaaaatcaa cgaaaggacg aatgctggga aatccgtata
    59581 acgcatacca gcgatatgtt cgaatagatt aactcctcca atacccgctg ccaagttggt
    59641 cgtatctgat aaaggcgagc agttattccc taaaaaggca ccggaaacga ctgcgcctgt
    59701 agtcattgca tcattgaatc caagtaaatg accgatcccc aaaaaagcaa ttccaatcgt
    59761 cgaaatcgtt gtaaatgaac tgccgacagt cactccgaca attgcacaaa caagaaatgc
    59821 tgtcggtaaa aagaaacgca cagaaacaag tttaaatcca taaaccataa tcgtagggat
    59881 ggttccagat aaaatccatg aagcaactaa gacaccaatc aaaagaaaaa tcaggattgg
    59941 aatgatccct ggagtgattc ctttgatgat cccgtcatgg atctcatccc atgtgaactt
    60001 tttaaatctg ccataaaaca acaaacacat gaaagctgca aggatcggga tatgtggcga
    60061 gagctggaat ccgatgatca gtactcctag gagtgccaac aacacgatca atacagcgat
    60121 actttctttt aaagaaatat ttttattcat cgtcgatctc ctatttcaaa tgaaaaggcc
    60181 ctgccatgaa aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg
    60241 gctgaaagac ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga
    60301 atctttcttg aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc
    60361 tactaataat gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat
    60421 agagaagatc agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg
    60481 gtaaggacgt tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa
    60541 aatgtacacg atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact
    60601 tacgtcatcc attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag
    60661 aacgacattt ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag
    60721 gaatccttca cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa
    60781 ttgtaaaagc acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa
    60841 gcctaggatt tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc
    60901 atctggtacg acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat
    60961 caaagcgata aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta
    61021 aacagaactc atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga
    61081 atcaatatgt tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt
    61141 tgagactagt ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg
    61201 gatatatacc cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa
    61261 gttcaagatc gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt
    61321 attgccaagt tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac
    61381 cattaccata cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt
    61441 gctgcccagt gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgtgga
    61501 aagctcaccg gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata
    61561 aaaaatcaat gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag
    61621 tgccattgtc agaccgataa aggtcccaag acccatttta cttacttcag atttactcac
    61681 cgttgacact ctccttgatt ttttggataa aataacggtg tctttgaagt agtttcagca
    61741 ataaacgaaa caattcagcg aatatttgag gggattcttt gagtttattg cttgaagggt
    61801 ttcttcaaag acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc
    61861 agatccaaac atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt
    61921 gcttattttg cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga
    61981 agagctgctt tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt
    62041 gtcattacgc tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgag
    62101 aatcctagtt ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca
    62161 gtatgtgaag ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca
    62221 tatacgtcat ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat
    62281 acatagtcta ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct
    62341 cctactttaa atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat
    62401 gcacccatta atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa
    62461 acgctggctg ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct
    62521 gggatatctg cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg
    62581 cggatatctt tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg
    62641 tcaatcgtta cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag
    62701 atataatctt tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca
    62761 aatggaatga agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca
    62821 gcatctacgt gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg
    62881 attttatcga taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct
    62941 aggattggtg ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc
    63001 atgcgatagt tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg
    63061 tcggcagctt ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt
    63121 tctaaatgtt ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg
    63181 ctgtctaaca gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt
    63241 ccagcaacta gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg
    63301 gcataccaaa gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca
    63361 tctttatagc tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt
    63421 gcaggagaag attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct
    63481 agtaaagatg gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc
    63541 caaggaacgg aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta
    63601 ttcacagtgt gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct
    63661 tgaggcatgt agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct
    63721 ttatagattt ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct
    63781 ttcgacaatg attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc
    63841 cctacattac acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata
    63901 ttttaatatg tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag
    63961 ggaatttaca aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt
    64021 ttaggatggg tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac
    64081 ttactaaatt ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa
    64141 ccacaaactt accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc
    64201 ggtcaccgtt aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg
    64261 gttcaatttt tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa
    64321 cgttcggcat tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc
    64381 cagagaacaa tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa
    64441 atcttgtaac ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta
    64501 cttttttcgc taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt
    64561 tcactacatc gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt
    64621 tcttcggatc aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct
    64681 tcagcatcaa tgggatcgtt aaaccgaacg cttctgcttc tggtccttct aattttcgga
    64741 ttaggtctaa tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca
    64801 catcgtatgt tttatgcaga tgcaaaaagt cgatagattg caggatttgg taagtaaact
    64861 ctgtaaatga gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt
    64921 tgatgttgaa gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc
    64981 agtcgtagtt gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat
    65041 tggaaagtgc gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt
    65101 tgcggccgct tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat
    65161 ggcctgccaa ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg
    65221 aatcaccagt tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc
    65281 gaagtctttc ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa
    65341 tattcatttt actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg
    65401 taattaatta tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc
    65461 aagggacgaa atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc
    65521 gaacatttaa cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt
    65581 taaagcatgt actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta
    65641 cttcgtttcg atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt
    65701 tctttgtcaa cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc
    65761 gctctaattc cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt
    65821 ttttctgcaa tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat
    65881 aaggaatggg acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca
    65941 aaaaattatt ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt
    66001 ttttgtcatc cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga
    66061 aaaagcaaaa gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc
    66121 tcaaagctac gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc
    66181 tactgaaaca caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg
    66241 gtctgatcct actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa
    66301 agccttccac tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt
    66361 caaccgttcg atcgaacaac tttatcaaaa tgattttgtt ttagttaatt tgaatgattt
    66421 gatccaaaaa gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa
    66481 aaaaccattg gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg
    66541 ttttcctagc cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa
    66601 agataaagaa gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa
    66661 acatcctgat ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg
    66721 agttttaggt tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga
    66781 gattaaagaa gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc
    66841 ccatacatgg ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa
    66901 tgaattgtgg cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc
    66961 atttggtgca gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta
    67021 cttgaagagt caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg
    67081 acaattaggt acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca
    67141 atctgattta gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta
    67201 tgacaaagaa gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa
    67261 ctgacatttt atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc
    67321 cttgatcagg acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg
    67381 cttagaaatt ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt
    67441 caaatccact tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact
    67501 ttcttgcgta tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta
    67561 tgtcatcaaa tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc
    67621 actcatggca atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc
    67681 ttgccctaaa tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc
    67741 aaaatattta aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt
    67801 cactccagcg gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt
    67861 ctttttctct tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa
    67921 acttttataa tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga
    67981 aagtatcaag ctagcaattc cttgtttatg aattcattga cagaaattta taaaaagaat
    68041 attatgtact aaaataataa aaaaagtttt ataaaaaggt ataaaacctt tttattaaac
    68101 tatttaatct tgtttagtat atatttttag aaaaaggagt ggggttttta tggcagaaat
    68161 cgtcaaagtc acacatttga aaaagagctt tggtcgtttc gaagctttaa aagatgtctc
    68221 tttcaccgta cattcaggtg aagtcgttgg atttatcgga ccaaatggtt ctggaaaatc
    68281 cacgacgatt cggacacttt tagggattat aaaaaaagac ggcggaacgg caacgatttt
    68341 tgggcaagat gtatgggaag atagtttatc tatccatgaa cgtctttctt atgttccagg
    68401 cgatatctct ttgtggggaa atttgactgg aggagcgatc atcgatctct tcatgaagct
    68461 tcatggaaaa gggagtgctc aaaaaaaaga tgaactgatt caacgtttct ctcttgatcc
    68521 taagaaaaaa gcaaaaaact attcaaaagg aaatcgccaa aaagtgggct tgattgctgc
    68581 tttggctgtt gattcggatc tctatttatt tgatgagcct acttctggtt tagatccttt
    68641 gatggaaacg attttccaag aagaagttga aaaattgaaa gaacagggca aatccatcct
    68701 actttcttct catattctca gtgaagtcga gcgactagcg gataaagttg tgatcatacg
    68761 cgaaggaaca ctcgatgaag aaggaacact cgatgaattg cgtcatttga ctcgttcgac
    68821 catcactata gaaacagaag cagagaatag tcacttagca caattgaacg gtgtccatga
    68881 ctttgtgcaa aaaggtcacc tcgctcaatt tgctgctgat aacgaagctt tcgatgtgat
    68941 tttagctgaa gcgtccaaat taggtgtgaa aaaatttgaa tctattccac cgactcttga
    69001 ggatttattc atgagacatt atgaaggatg aggaggaagc gaaatgactg ataaattttc
    69061 acgctggtcc accctttttt ctcaaaacct tagccgtgac tggaaaaaga tcctgatatg
    69121 gctagtcggt gtcactgctt tttctggtgg ttttgtccct gcgtttgaag aattgacttc
    69181 cggacaagga ttagctggat tatacgaaac cttgcaaaac ccggcaatga ttgcaatggt
    69241 cggaccaact ccagcttcga atgctgctga gtatacttta ggagcgatgt atgcaaatga
    69301 aatgttgctt ttttgcagtt tgtttgctgc tgtgatctct gttttacacg tggtgagcca
    69361 aacgagaaaa aaagaagaac ttggtctgat tgaacttatt cgttcctttc gagtcggacg
    69421 tcaagcaaac tctttagctg tcatcgctga aagtattctg atcaatttgc ttttagcaat
    69481 atcgatcagt tgtacgatga tttttttcca agcggattcg atcactgcag aaggtgcttg
    69541 gctttttggg ctatctgtag gtagtatggg gattttgggg agtgccgttg cactgtttgc
    69601 tgcacaactg atgccaagtt cagccagttc gaatggtctg tctttagcgt ttttaggtgg
    69661 actttacctt ctacgagcaa taacagatgt agctgattcc tccctttcga tgtggaatcc
    69721 tttaggctgg tcttatttga cctatccatt tacaactaac aactggattc ctttgcttta
    69781 tttgtttttg ttcagtctaa tcttgataat cagttcattt gttttagagg aacatcgaga
    69841 tttgaacacc ggctatatcc ccgaacgtga aggaaaaccg tatgctaaac gttctctttt
    69901 atccttgcgt ggtttattat tctatctaaa taaagggatg acaatcagtt ggcttatcac
    69961 ttttggtttg atgggggcgg catacggctc tatctacggg aatatgcaac agtttttaga
    70021 aagtaacgac ttaatgaaac agatgtttat ccaatctggc gtctcaattg aaaaaaactt
    70081 tacaagcacg atcatggtcg tcttgatttg tctagctgct attttaccaa ttgctagcat
    70141 caatcgttta tttacagaag aaacccacgg acgtatgaat cagctgttcg caacaaaaat
    70201 ttctaggaac caactttatt ggaccaatat gttactagct attctatttg ctatattggc
    70261 aatcctgatt agttctggtg cactagggct ttctgctttg gcttcgatga aggatgcgaa
    70321 agacatggat ctattgatgt ttcttaaagc cgggttcaat ttcctgcctg ccgttttagt
    70381 gtttatcgga attagtggct ttctattcgg atggcttcct cgaatcggta aacttgctta
    70441 tatctactta gcttactcct ttgcactcaa ttactttggc ggaattttgg atttaccaga
    70501 atggttttcc aaaacagctg tccctagctg ggttccacgg atgccaaacg attcttttga
    70561 tctttccgtg ttccttacgt tatcatgtat cagccttgca ctgttcgtcc ttggttctat
    70621 tggttatagg cgaagagact tactagaagg ataataaaaa agcatgtaca atttcatgct
    70681 agcctccaaa tctgggtcaa aaatccaaca tttggaggtc atttttttat ttacaagtct
    70741 tctaactgct ctttatcaat gatccagact tctcgattct ttctttttac ataaccattc
    70801 tcctctaata atttaaattt tctagataaa gtttcggggg tcgtaccgat aaatgcagca
    70861 agttctttca ttttcattgg caggaaaaag tgatccttcc ctgtcgcttt agctaagtca
    70921 agcagataga cagcgactcg ttcttctact ttttccatca tcaaaaaagt tgtctgctgc
    70981 tgtacttttg ttaatttctc aacgttgatt gctaaaagtt tcagactaag ggcgggataa
    71041 tgcagtaaga gttccgagaa atctttttgt ctcaatatgc aaatttccgt tttttctagt
    71101 gcttcgccaa ataaagactc atttggaacg cctagcaact ggctctctcc ctcatatccg
    71161 cccggctcta ttactcgtaa aagctgttcc tttccgctag cagataattg atacactttc
    71221 atactgccgg aggccacgat cactaattga ggttctccat tcggcgcaag aatctgttct
    71281 cctttttcca catagtgatg tttgacaagt gcgtgtactt tttcttgatc ttgctgtact
    71341 aagtgattga acaaaggaac aaatgaaaca cataaatgat catgactcat aatctctcct
    71401 ccttctaaac agctatttct aataaagaaa cataacttcc cttattccaa ctgataattt
    71461 tcttttatca tagcataaac gtcaagcgaa ccagatacca gcaaatagag tggatttctt
    71521 tttgtccctt gctttatttt ccttcttttg agaccttaag taattgattc ctatcaattt
    71581 tttaaatatt tactttttga ataatcaaaa acaaaccttc actcgcaagc cgagagtaag
    71641 gtttgttttt cgcattgctt atttcgtgtt gtctattgaa atttttccgc acctagcttt
    71701 tgatatagtg gtgctagttc ttgtaaggtt tcagcggtta tttgctcaac gtgttcgatt
    71761 tcttgcggat agaagaatag tttacccatt tgaaaggttc ggtctctcat cgcttttttc
    71821 aactcttctt gtttctttgt atcggacaaa tagtcagaca aagctaagtg gtcgtcaagt
    71881 tcatgttctg gttgcggcca tatgtaataa tccttgatat cgactgtttt gctccactct
    71941 ttcagtatcg caagcaactg gttatacgct gcaatgctac catatcgttc ttcgctttta
    72001 taatgttggt acatcaaata gatttggtat tgtttttgat tcaacaaaac tgctagacag
    72061 gcattctcgt cttgacgaga ttcgcttcgg tacgcgctcc aaaaatgact gcgtaaattc
    72121 cagccattcg tccagctttc gattttaggt ttgctcatgc cgtacatatc aggcaaaagt
    72181 gcagctgtct ggagctgaat ctctttccat ttttgccagt gttctttata ttctttcttg
    72241 atttgttcaa tcttatctgt tggatggctc tctttgagct gtttgaatgc gtagattggt
    72301 cgatcaaaca actgataatc tgattttcca agttccattg tttcgcctct ttccgttatc
    72361 ttttgtattc tacctgaatt ttgcgatatg gacaaataga ggttgtgaaa aagctgttct
    72421 gcatcaagtc ataagaacag ccaaacaaaa aactgcgatg agcatcaccg cagttttatt
    72481 gaacttaagg ttgattgatc acatctaaaa gcgttgaaaa taaaatggca ctagaagcag
    72541 ctcctgggtc gatatgtccg attgcacgct ctcctagata ggaagctcgt ccttttttag
    72601 ctaccaagac tttggtgtgt tcttttgcct ggtcaatgat ttcttttgtt aaattccctg
    72661 ccttcaatgc ctctgtgact ggcagccaaa catctaacat cgttttatcg tcagcttctg
    72721 cctttcctcg gctttgaata cccgctgttc cctgctcgat cacttcgcct aatttttctt
    72781 gagaatcaat agaatcgacc tcttttgtcg ctttcatcat gttcatgaat gcagatccgt
    72841 ataacggacc agaagcccca ccgactttcg atatcatcgc catagagaat actttgaatg
    72901 tatcgctgat tgtttcagga tgatcggctt gaaaagcttc ttcataagct gaaacccctc
    72961 ttcccatgtt atttccatgg tctccatcgc caatcggggt atctagatca ctgagatatt
    73021 gtttgttctg attgattgcc tctgcaaatt gcgtgagcca ttcttggatt tcttgaacgg
    73081 ttagtttcat attatcaccc ttttatcttg agatttttta ccatgaaatc gtctgtacat
    73141 tgctttctaa agaatctttc cattgtgtct ccgtcaagtc gatcagtgtt agagaaagac
    73201 cttgcatatc tagtgaggtc ataaaattac cgacttttcg gaaaactaca ttgacgcctc
    73261 tttcttccaa cagagctaaa acatcattca tgaacacgaa ctgttccatc aaaggcgtcc
    73321 cgcccattcc gttgactagt acacctgctt cttttggtaa attcgagtaa tcatctaaaa
    73381 tcttagtaac aagttccttt gccagtactt tagaaggctg catcttttct cgacgatagc
    73441 ctggctcacc gtggatacca acaccatact cgatctcatc ttctcctagt tcgaatcctg
    73501 gtttccctac ttctggtaca gttgctgctc gaagcgctag accgatcgtc ttagttgcct
    73561 gtacgacctt ttctcccagt tctttcaact cagctaggga agcaccgttt cttgctgcat
    73621 cgcccacgat tttgtgtaca aggacagtac ctgcaactcc gcgttttcca gcagtatacg
    73681 tactattttc aacggcgata tcatcatcta cgatcacact ttctacttca atatcgtcca
    73741 tagcagctaa ttcctttgcc atatcgaagt tcaatgcatc ccctgtataa ttcttaacga
    73801 tcagcaaaac tccttttcca ctatcggctt ccttaatagc cgtctgaatc tgatctggag
    73861 ttggagaagt aaacacatca ccaagcaccg ctgcacttaa catcccttcc cctacaaacc
    73921 cggcatggga tggttcatgt ccgcttcctc caccagaaac caaaccaact tgttccgctt
    73981 tctgattctt ggctacaaca cgggaagatt ctacacgatg aacaagttct ggatagcttt
    74041 ttactaatcc ttccagcatt tcttcgacaa tattgcttgg atcattcatg atttttttca
    74101 atttattccc atcctttctt tccggcattt tgtgcttctg ttaagatttg ctgagtatca
    74161 tctgttatac cggcagtgat ggctgctgca aaagctcctt ccactaaagg cgcatccacc
    74221 agatgataac gttgctgctg ctcttcttcc aacatgtctt ttgccagttc cgagttcaat
    74281 accgcgctac cgatatccgc aaaaacaaaa taactagctg catcgcttga ttcattgact
    74341 gcttctacga ttttcatcgg gtctgatccg atctcgccat ttattccgcc gagagaaaaa
    74401 atttgcacct cttcggattt ttgcatctgc tcaatcattt ctttaatacc atctgttact
    74461 ttttgactat gagaaataag caaaatactt tttttcacaa gaatcttcct ttcttttaca
    74521 tagttgctaa cgattggttt cgctttcatt aatgaacaat tcaagtatat aataaatttc
    74581 taattttggg aaaatatgtg tagtgcttct tgaagtttgt tatactttaa tta
//
LOCUS       DARPZJ010000009        72317 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.009, whole genome shotgun sequence.
ACCESSION   DARPZJ010000009 DARPZJ010000000
VERSION     DARPZJ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.009"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(157..1299)
                     /locus_tag="SLE23_000757"
     CDS             complement(157..1299)
                     /locus_tag="SLE23_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8467680.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGICLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(1304..1489)
                     /locus_tag="SLE23_000758"
     CDS             complement(1304..1489)
                     /locus_tag="SLE23_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEI8467681.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(1843..2088)
                     /locus_tag="SLE23_000759"
     CDS             complement(1843..2088)
                     /locus_tag="SLE23_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467682.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(2082..2483)
                     /locus_tag="SLE23_000760"
     CDS             complement(2082..2483)
                     /locus_tag="SLE23_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8467683.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(2668..4476)
                     /gene="uidA"
                     /locus_tag="SLE23_000761"
     CDS             complement(2668..4476)
                     /gene="uidA"
                     /locus_tag="SLE23_000761"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEI8467684.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KLITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWKERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLQKRWSSIPNFSYKK"
     gene            complement(4499..6265)
                     /locus_tag="SLE23_000762"
     CDS             complement(4499..6265)
                     /locus_tag="SLE23_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEI8467685.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IISDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIEPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(6278..7072)
                     /locus_tag="SLE23_000763"
     CDS             complement(6278..7072)
                     /locus_tag="SLE23_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8467686.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYYQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGEYVDIEQKFIDTFWKNLTNK"
     gene            complement(7082..8458)
                     /locus_tag="SLE23_000764"
     CDS             complement(7082..8458)
                     /locus_tag="SLE23_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8467687.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLIIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQFKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKTSNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANIQTGDVLEKLYNASTLIPSICFFIVGLILFFLYPLSKDKVLENC
                     ELLKQKYK"
     gene            complement(8578..9225)
                     /locus_tag="SLE23_000765"
     CDS             complement(8578..9225)
                     /locus_tag="SLE23_000765"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HEI8467688.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSLENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(9318..10745)
                     /gene="uxaC"
                     /locus_tag="SLE23_000766"
     CDS             complement(9318..10745)
                     /gene="uxaC"
                     /locus_tag="SLE23_000766"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEI8467689.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLGYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(10819..11898)
                     /gene="uxuA"
                     /locus_tag="SLE23_000767"
     CDS             complement(10819..11898)
                     /gene="uxuA"
                     /locus_tag="SLE23_000767"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEI8467690.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLQTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(11901..13532)
                     /locus_tag="SLE23_000768"
     CDS             complement(11901..13532)
                     /locus_tag="SLE23_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEI8467691.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSNIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            13838..14509
                     /locus_tag="SLE23_000769"
     CDS             13838..14509
                     /locus_tag="SLE23_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8467692.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQHGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKINNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKSI"
     gene            complement(15212..15567)
                     /locus_tag="SLE23_000770"
                     /pseudo
     CDS             complement(15212..15567)
                     /locus_tag="SLE23_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15584..15751)
                     /locus_tag="SLE23_000771"
     CDS             complement(15584..15751)
                     /locus_tag="SLE23_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467693.1"
                     /translation="MQTLINALQGKNYDYAVKILLDVAKRSLTPAQFAKFNAATIAAG
                     IAINAISCWGK"
     gene            complement(15751..16158)
                     /locus_tag="SLE23_000772"
     CDS             complement(15751..16158)
                     /locus_tag="SLE23_000772"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467694.1"
                     /translation="MSRFFKFFSLLGVMLIGLSTLVGAGTSVYAAEKVNEVPDIETQR
                     QQAVESLKFYLEEAGYVDTETHQYIVTDLEAIQKKAELDGSEGIAGKFILENFVQPTG
                     KRQKRDLQKYAACVVMNSLPFGVLFGIYLIVKI"
     gene            complement(16659..16853)
                     /locus_tag="SLE23_000773"
     CDS             complement(16659..16853)
                     /locus_tag="SLE23_000773"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467695.1"
                     /translation="MKDQKTNNKTGERSACSWAFTGAGLLHSGIYTAAALGLSLTGVG
                     AAVIPFAVGTAYGIAGAAIC"
     gene            complement(16867..17205)
                     /locus_tag="SLE23_000774"
     CDS             complement(16867..17205)
                     /locus_tag="SLE23_000774"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467696.1"
                     /translation="MKRIVKIFGILGVFLIGLSTFVSAGISVDASETNNFLVKQQETE
                     INIIQNNLATHKDSKGNRLVYIIDESDLKSSLDRINSEITVSEIQQYLNEFNRSIQKK
                     WPWMANRSAS"
     gene            complement(17249..17581)
                     /locus_tag="SLE23_000775"
     CDS             complement(17249..17581)
                     /locus_tag="SLE23_000775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467697.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRKEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLVWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(17595..17852)
                     /locus_tag="SLE23_000776"
     CDS             complement(17595..17852)
                     /locus_tag="SLE23_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467698.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KVYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18047..18583)
                     /locus_tag="SLE23_000777"
     CDS             complement(18047..18583)
                     /locus_tag="SLE23_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467699.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLTTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDYMT
                     DRCIKDNSIDVDPHVQMKTTGKLHQVTQDIENPDQYLLFGEETTNEVTQFVLLQLKVD
                     QEAQKIDAIKIYYVRSVY"
     gene            complement(18604..19695)
                     /locus_tag="SLE23_000778"
     CDS             complement(18604..19695)
                     /locus_tag="SLE23_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEI8467700.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEDGGEATGLAVAFNWE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESTYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKDCYDYYGFLVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYQGAMSIIKSYNLTEYDTFAIKHWNSLPTKK
                     SSLVAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YDWTAYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSDGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(19703..21913)
                     /locus_tag="SLE23_000779"
     CDS             complement(19703..21913)
                     /locus_tag="SLE23_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467701.1"
                     /translation="MAYIKRKEKKWCVWLFLTVGFGLFFVGGLVYAVEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYLLLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLGIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPAFDYMIMNTLKSFLSLMFQKSFYSVIILVAFLIY
                     NIVDDLILMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGGQVINPFELGGRSNQDLPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQSSKQQGNNQRKPLLNKGIAFVGQSIPLPAGKVPVPQLTAAGSLS
                     QQIHQVKNQAKNGSYPAMQQLLNQYSVPKSSVATLSGNRSVQRQIQRSSESKPSISVP
                     KSLQPAFSSFNNPVEQSKKIEKKNETLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(21929..24457)
                     /locus_tag="SLE23_000780"
     CDS             complement(21929..24457)
                     /locus_tag="SLE23_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8467702.1"
                     /translation="MVLVKEPVKALKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFYDVLNLIWLDVAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRMPKEHKGLLQLEDELGTSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEYKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATIIQQLHTTIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAIGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVEYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILTHLRLEVNEANLSEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQIEEQDTLIMQ"
     gene            complement(24511..24921)
                     /locus_tag="SLE23_000781"
     CDS             complement(24511..24921)
                     /locus_tag="SLE23_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467703.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFFIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYVV
                     RMMNGDCVYYNWDKVSNNALEELLFANKYVYLED"
     gene            complement(24934..25152)
                     /locus_tag="SLE23_000782"
     CDS             complement(24934..25152)
                     /locus_tag="SLE23_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467704.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25149..26141)
                     /locus_tag="SLE23_000783"
     CDS             complement(25149..26141)
                     /locus_tag="SLE23_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8467705.1"
                     /translation="MKKRQLRRKEKVYTEKVPNQRKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSQSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQEILKKEFYAQNFIQEPGSVSGIRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMDPENKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKTFIVKATVVFRDGDTSLLQKEQMTLVITKKTNQYYVEKLTHNWLDRKGDERK"
     gene            complement(26220..27131)
                     /locus_tag="SLE23_000784"
     CDS             complement(26220..27131)
                     /locus_tag="SLE23_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8467706.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLSDVETELNGGTTEKPAEPEHLQPEKPEKEPVAPEPEIPESTLPTDPIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSETNTDSSSTEQPTMSFTSEEPKEEPKQPAEKSEAIPK
                     ENKPIVPAKEVTVSVTPNGEITTNNSQGMSVPIVTSNVEELTHIPTPTTPLKAEGGQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEVKTADGKTKVLPKTGEEIHVVLS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27150..27494)
                     /locus_tag="SLE23_000785"
     CDS             complement(27150..27494)
                     /locus_tag="SLE23_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467707.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLGPRTERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(27514..28071)
                     /locus_tag="SLE23_000786"
     CDS             complement(27514..28071)
                     /locus_tag="SLE23_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467708.1"
                     /translation="MSLEFLGEPIEKEEFVSHYMDLFIRVIKKLCTIDEFYPREQDYL
                     AAERIKISLLWEKFTDENNRPPDYRYLSDCLTNNVLSKEYLFHKREKNQMSAEHFCDC
                     YIALLRSQQLLTVERYGAEFGYVMQAERHRATRCYEKEDQVIDGYEELCIRNNRYLQQ
                     RLYEKLMMDFSDLYRGYECSVIQER"
     gene            complement(28151..28651)
                     /locus_tag="SLE23_000787"
     CDS             complement(28151..28651)
                     /locus_tag="SLE23_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467709.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPKEYPIEKRELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPINFLKKC
                     HLRILP"
     gene            complement(28652..29197)
                     /locus_tag="SLE23_000788"
     CDS             complement(28652..29197)
                     /locus_tag="SLE23_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467710.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGTLKFIRFYRFSLPVPAILAVK
                     KGCDKMKIYENCVAALSNEKPLVEEISLATVTWEMNRQPTEEQTYLSLEEIELELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29194..30450)
                     /locus_tag="SLE23_000789"
     CDS             complement(29194..30450)
                     /locus_tag="SLE23_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8467711.1"
                     /translation="MTPIELRNYRKKLSAIHASGGGKKLLSQKRFAQLLGCSVDYIKK
                     MEQGKKKIPEDFEKRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKIVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKQTVTQNVLVQFSGQGCREYEEVMREQRTD
                     WRTWLYSIWKNQGKLEAGYKRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKKFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISEIEAL
                     TKYGIYNRYELRLANEKATQAVEAFILDHSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDERWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIENAELNDEQQSYLEWMGTSGGKIA"
     gene            complement(30813..31127)
                     /locus_tag="SLE23_000790"
     CDS             complement(30813..31127)
                     /locus_tag="SLE23_000790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467712.1"
                     /translation="MGEVLYRVSSAAGEISPDFAVRRLYEWINKVEYYTKGSYVFRRI
                     ERETLFVTRNQIVLTKEDILRFRQVYRLCKEKNIQLRLAILQCFAPEQYKELQEKEDS
                     LV"
     gene            complement(31254..32447)
                     /locus_tag="SLE23_000791"
                     /pseudo
     CDS             complement(31254..32447)
                     /locus_tag="SLE23_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(32637..32993)
                     /locus_tag="SLE23_000792"
     CDS             complement(32637..32993)
                     /locus_tag="SLE23_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467713.1"
                     /translation="MNLDKTNQTLREIMVCCQNIQQLIEYFGDNPTIFIQTNEYICAV
                     IGQCMFLRDLVRFSLPYQWKQDHQEVVWIRVVRICNMCAHPYKNRLNLFRLWFFIKCD
                     IPVLVAFCQKFLAQEK"
     gene            complement(33059..33511)
                     /locus_tag="SLE23_000793"
     CDS             complement(33059..33511)
                     /locus_tag="SLE23_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467714.1"
                     /translation="MGLKFPNNYDITEALDETCIGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNSNPKQSQEKGLDQKQPSADSKEKEKK"
     gene            complement(33513..33878)
                     /locus_tag="SLE23_000794"
     CDS             complement(33513..33878)
                     /locus_tag="SLE23_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467715.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIEEVL"
     gene            complement(33895..34089)
                     /locus_tag="SLE23_000795"
     CDS             complement(33895..34089)
                     /locus_tag="SLE23_000795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467716.1"
                     /translation="MEKKNINICFLSGKECTYEECTDISVHERDGMLIVDMSPSDEPF
                     VVKHYFPLCNIESFRIDCEF"
     gene            complement(34106..34351)
                     /locus_tag="SLE23_000796"
     CDS             complement(34106..34351)
                     /locus_tag="SLE23_000796"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467717.1"
                     /translation="MEEIFFCMMVEFLFVSIGFLIMGEAIMIYLFPFDSKDECIFSSI
                     IIFFILACVWILAREIYHQFVLEDGKGIITWFLQKRK"
     gene            complement(35067..39362)
                     /locus_tag="SLE23_000797"
     CDS             complement(35067..39362)
                     /locus_tag="SLE23_000797"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HEI8467718.1"
                     /translation="MYAKTKMNWLKALALVALSQFCFLVGTAQAHAEETTATQPTVEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPVT
                     SQPVEETASITTPASETSTPEGEKAAEATPSVKPESSEKQAEEKQRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKLNKESTASIEDQKKKEQDIPKTGTPTLLVTVP
                     TNRSVRVRRATNTAVLGGRKIDWGENIGVTSSPNNPNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALENYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLLNNFDVRATFHNQTHTIKIGETLKVKSGNDFLQRV
                     KGIQKPKGINVSIHGNEAWITVTKEAPEKAKIHFNQIEVLGTPLAYRRPGAQTIGILN
                     PFEPGDSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KNMNGKVQAEIKDLDPGKYVLKEIKAPKGYALSDETIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKIANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKERYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVT
                     FTLYNGKGQAIGKYTTDQNGEILVKGLVANNYYFTENVPLESFQPNTGKQAFTITFRQ
                     NAPDDGETLLVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQEGKEITSILTFIADKANGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAVHVDINDDNQSVRVNNPTVHTTAVFEDGLTIADPTGLFTLNDTVEINE
                     ILPGKAYLVKGILMDKATGEALLVHGQPVESAVGFIAKAENETVIVPFTFDLTGLNGR
                     EMVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLIVGKTYTVNGVLMDKVTEKPVLVDGKEVSSTLTFVAETTDGTVNLDFILD
                     AHALRSKEVVVFEDLFREGVLLASHADITDKDQTIKIVSPTITTKATNANGGKEILAL
                     PNQKVVEWVQVNGLAIGQIYKLIVQGYLTPDGTPFEGTHAEKVFMADKEMMEFLFEFI
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQFVEAPKPPQPVK
                     PNEPQPVKEVKQAAMVPMLPKTGSEDNVLWIMIGMIFVLAAGLIGYDLYKVRD"
     gene            complement(39509..39748)
                     /locus_tag="SLE23_000798"
     CDS             complement(39509..39748)
                     /locus_tag="SLE23_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467719.1"
                     /translation="MIDISIPEDLKPDPATIGNSGMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMIFGDGEVANKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39838..40110)
                     /locus_tag="SLE23_000799"
     CDS             complement(39838..40110)
                     /locus_tag="SLE23_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467720.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(40193..40444)
                     /locus_tag="SLE23_000800"
     CDS             complement(40193..40444)
                     /locus_tag="SLE23_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467721.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFVESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(41442..42353)
                     /locus_tag="SLE23_000801"
     CDS             complement(41442..42353)
                     /locus_tag="SLE23_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467722.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGQLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEISKESNRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFNKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42550..44385)
                     /gene="lepA"
                     /locus_tag="SLE23_000802"
     CDS             complement(42550..44385)
                     /gene="lepA"
                     /locus_tag="SLE23_000802"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEI8467723.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44532..45752
                     /locus_tag="SLE23_000803"
     CDS             44532..45752
                     /locus_tag="SLE23_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467724.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45772..46266
                     /locus_tag="SLE23_000804"
     CDS             45772..46266
                     /locus_tag="SLE23_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEI8467725.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            46244..46930
                     /locus_tag="SLE23_000805"
     CDS             46244..46930
                     /locus_tag="SLE23_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467726.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(47081..49690)
                     /gene="clpB"
                     /locus_tag="SLE23_000806"
     CDS             complement(47081..49690)
                     /gene="clpB"
                     /locus_tag="SLE23_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HEI8467727.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(49941..50987)
                     /locus_tag="SLE23_000807"
     CDS             complement(49941..50987)
                     /locus_tag="SLE23_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HEI8467728.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(50998..51270)
                     /locus_tag="SLE23_000808"
     CDS             complement(50998..51270)
                     /locus_tag="SLE23_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEI8467729.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(51305..52213)
                     /locus_tag="SLE23_000809"
     CDS             complement(51305..52213)
                     /locus_tag="SLE23_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HEI8467730.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(52345..53577)
                     /gene="pepT"
                     /locus_tag="SLE23_000810"
     CDS             complement(52345..53577)
                     /gene="pepT"
                     /locus_tag="SLE23_000810"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEI8467731.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(53592..54713)
                     /locus_tag="SLE23_000811"
     CDS             complement(53592..54713)
                     /locus_tag="SLE23_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEI8467732.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(54710..55411)
                     /locus_tag="SLE23_000812"
     CDS             complement(54710..55411)
                     /locus_tag="SLE23_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEI8467733.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(55555..55995)
                     /locus_tag="SLE23_000813"
     CDS             complement(55555..55995)
                     /locus_tag="SLE23_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEI8467734.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(56124..57050)
                     /gene="dnaI"
                     /locus_tag="SLE23_000814"
     CDS             complement(56124..57050)
                     /gene="dnaI"
                     /locus_tag="SLE23_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEI8467735.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(57050..58423)
                     /locus_tag="SLE23_000815"
     CDS             complement(57050..58423)
                     /locus_tag="SLE23_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEI8467736.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(58446..58937)
                     /gene="nrdR"
                     /locus_tag="SLE23_000816"
     CDS             complement(58446..58937)
                     /gene="nrdR"
                     /locus_tag="SLE23_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEI8467737.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(59249..59581)
                     /locus_tag="SLE23_000817"
     CDS             complement(59249..59581)
                     /locus_tag="SLE23_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEI8467738.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(59633..60262)
                     /locus_tag="SLE23_000818"
     CDS             complement(59633..60262)
                     /locus_tag="SLE23_000818"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEI8467739.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            complement(60226..61062)
                     /gene="mutM"
                     /locus_tag="SLE23_000819"
     CDS             complement(60226..61062)
                     /gene="mutM"
                     /locus_tag="SLE23_000819"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEI8467740.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(61107..63752)
                     /gene="polA"
                     /locus_tag="SLE23_000820"
     CDS             complement(61107..63752)
                     /gene="polA"
                     /locus_tag="SLE23_000820"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEI8467741.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(63878..64561)
                     /locus_tag="SLE23_000821"
     CDS             complement(63878..64561)
                     /locus_tag="SLE23_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEI8467742.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(64554..65039)
                     /locus_tag="SLE23_000822"
     CDS             complement(64554..65039)
                     /locus_tag="SLE23_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HEI8467743.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(65346..66680)
                     /locus_tag="SLE23_000823"
     CDS             complement(65346..66680)
                     /locus_tag="SLE23_000823"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEI8467744.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(66811..67572)
                     /locus_tag="SLE23_000824"
     CDS             complement(66811..67572)
                     /locus_tag="SLE23_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEI8467745.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(67588..68070)
                     /locus_tag="SLE23_000825"
     CDS             complement(67588..68070)
                     /locus_tag="SLE23_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEI8467746.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(68090..70270)
                     /locus_tag="SLE23_000826"
     CDS             complement(68090..70270)
                     /locus_tag="SLE23_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEI8467747.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(70414..71145)
                     /locus_tag="SLE23_000827"
     CDS             complement(70414..71145)
                     /locus_tag="SLE23_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEI8467748.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(71214..72155)
                     /locus_tag="SLE23_000828"
     CDS             complement(71214..72155)
                     /locus_tag="SLE23_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEI8467749.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
BASE COUNT        21154 a        15196 c        11173 g        24794 t
ORIGIN      
        1 ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct cgtccatttt
       61 cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaaaa aaaaaatagg
      121 ctgtgacagc agcgtgacag caaaaaagat ggaaagttaa atatcaaacc tcgtaatttc
      181 atttgcgagt gcttgatttg tttctggata taagtgtcca tatttgtcca aagtagtttt
      241 aatagaggca tgacctagac gcttagatat tgcatagata tttttattat gttcaattaa
      301 aaaggcaaca tgcgagtgtc ttaatccatg catatgaatt ggttttactc ctgcaatttc
      361 agctaatttt tttattctgc ttaaaatagt tcttggagat ggcggtaatc catcaaaaga
      421 aaaaaccaat tctatatttt tcccaattga ttgttgagtt tttttccatg tttttaaatc
      481 ttcaacggtt tgtctgtcta acgaaattat ccgaatactt gatgtatttt ttgtttcagc
      541 aaattcataa tcttgtcttg tacggatgta aattgactta tttacgctac atctgccatt
      601 tattaagtca aagtctttcc attgtaacgc taagagctcc tcactcctta cacctgtaac
      661 aaaaataaaa cgcatcaaac gtttataaaa ttcttcataa aaatccccgt gataaacact
      721 attatatact ttcttaaatt catcaactgt ccaaaattct acttgaggac gctgagtttt
      781 tattttacct atagtatcta caggattttc ttcaataatt tcaagtacaa ttgccctttt
      841 aaaaactact ctcaacttat tgaatatctg tttaatataa tttggtgata atggttgctc
      901 aatgcccttt tttacaacat ggattttcga taaaaactgt tgaaattcct gtatatgaat
      961 tggtcgaatc tttacaacct gcatttctcc aaaaaaatcc aatgcacgtt gtaaaatatg
     1021 atctgttttc atatatgttt tttctacagt tcccaactta taccaaggaa aaaaatactc
     1081 tcgataaaaa tcatgaaacg ttattccttg cagacaaatt ccttgtgaat cagaaaaact
     1141 ttgttttaac tcttcgagtc cccttctagc ttctccttga gttttgaagc ctcttctggt
     1201 cacttgaatt ctttttccaa agcgatcttg tcctaaagtt gcagaaaaaa accaagtgcc
     1261 tctttttctg tctttataaa cattcgcaat tttcctcatt ttactattcc tcccaagaaa
     1321 tatggagaac ttcttctaaa attgaaatag gaattctttt tatttttgaa ttacgataaa
     1381 aaaagtatcc tttctcaact aaaagttctt tacattcctt gaagatttta ttagcatagt
     1441 actgagaaaa acctagatta atcaaatctt ttcgagtagc tgttttcatt atagcacctt
     1501 ccttactttt tttcatttat ttctatcagc tgcttttgtc aaaagcacat aggaatttca
     1561 cctctcccca agtttacggc gagccttacg gaagtatcat tatcccaact ttaaatcatc
     1621 gctttttatt gactataaaa attattttag aatatttatc gctccttctt tacagcaaga
     1681 aatcatggcg caactaaaat atgctcctta aagtgttaac gtactgatag aatctattta
     1741 attttcaatg aacaataggt tttctaccta aaagaatcta ctaattcctt aactattaga
     1801 agattctttt aaacagaaaa agtggaaagg agattttttt aattagttaa ttttaaattt
     1861 taagatcgct tctattaatt taatttctag ctgacttatc atatattcat ctacataggt
     1921 aacgaattga cctacctcgt taaatccatt tgtcaaacat aacttagcca tataactatg
     1981 ataatgtttg agtatcatct tgatcgaaat tggatctcct tctagagcag ataagataat
     2041 ggatagtgga actaataggt actgccgctt tttggattta tctaccatag gtcatacccc
     2101 attttcaatt gttcaactgc cttctttcgt tgataccaga taccacttgt gctcatattg
     2161 agaattttac cgatttcagc atcattaaaa cctgcaaaat aataaagtag gataatcttt
     2221 cttcttatct ccgataactg atcaattgct gctgataact tttgatctga aattaatatt
     2281 tccattccaa ataagaaata gacatcttgt tcatcaaaat gagtttggga atacctgcct
     2341 tcatttgaat ctgccaatgg ttcctcatta tcctttatgt tagcatttcg ttttcgaata
     2401 gacttagctt cgtttcgtaa tactttttta cagtaggcat caaattggtg ttgtatagat
     2461 atgtcattgt aatgttgttg catgataata tgctcctttt tccccctttc cactaataca
     2521 acaatcagag agcccctttt tttcgaaaaa actagaaaaa aacataaaaa tatttatcat
     2581 tctttaaaca gaaaatcttt ctataaaaaa caaaaaaacg attaggctag gctaatcgtt
     2641 ttttgaacat tcttaaaaaa atccaaatta ttttttataa ctgaaattgg gtattgatga
     2701 ccatcgtttc tgtagatagt gagcaatcat tttaggtttt ctatctctag taaagattcc
     2761 tttcttattt ccttgcactc ttaaaatccc ttgactcgtt gcaaaatctg caaaattcca
     2821 cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg cttcgtaata
     2881 agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc cagctactgt
     2941 atctgctcca tattctgtaa acattattgg cgtatcagga catctttctt tccatccatc
     3001 tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa cataccaacc
     3061 ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa tatctggcgt
     3121 tgattttaga taagtaacta ttgttacagg tcttttctgc ggatcaagtt ctttagttaa
     3181 ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg gttcatttgc
     3241 aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt ccttgatcac
     3301 cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt ccacattatc
     3361 atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt catcaataac
     3421 tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat aatgtgatgt
     3481 tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat ttacagcctc
     3541 attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt taaaataaaa
     3601 aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa taccaaattc
     3661 ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca tactatataa
     3721 ataagcatct agaggttccc aaaaaattgg attcttaagc tgaatcattc ctttctttcc
     3781 ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga tttttccggt
     3841 ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc ttgtattaat
     3901 agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc tatgaatacc
     3961 tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc cattttcctg
     4021 tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat tgtttacagc
     4081 aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact caaatggtgt
     4141 aaacccacct ttgtgttgag taatcaactt tccattcaaa aaaacttttg cttcatgtgt
     4201 tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa gagtcacttc
     4261 tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa ataaatcatt
     4321 ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt ctaaagcaag
     4381 ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc ttaagtcaat
     4441 tacttgcctc gtctctgtca taatgggata caacatataa accactccta tctaaatatt
     4501 aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc ttaaattcag
     4561 aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca tcataagtat
     4621 taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt acagatacaa
     4681 aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta cttgctggcc
     4741 agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc aagtcatatt
     4801 ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata tttttaattt
     4861 tttcttcttg cgataatcct ttcaactctt cttcaggtga aatgtatttt tcaacttcaa
     4921 atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta tttccagcaa
     4981 ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc cttttatatt
     5041 tttctggttc aataggccaa atatcttgtt tatctttaac taatgtaatt gcttggtcag
     5101 ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga gcttcttgct
     5161 taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct tttaacccta
     5221 aaattctttt taaggcatct aataaccgat catcagagat aattccttta cgataacctt
     5281 ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga tcacatccag
     5341 ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt cctaacatat
     5401 gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt aagtcagtga
     5461 ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca ggattaaaat
     5521 gttttgaata agctggcata tggatatgac ctgccataat cgaaggtaat ccagcttcta
     5581 ttaaacctga gtatactttt ccaaaagaat tatcccattc ttccgtacct aaactattaa
     5641 tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa tgtttagctg
     5701 caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt tctaaaactt
     5761 tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa tttctattaa
     5821 tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca atcccagaaa
     5881 ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt acttctacac
     5941 caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta gcagcaatta
     6001 ataaaggaat tttgctttct gtttgtagga tatagttttg atcatatacc tcatcagcag
     6061 ttcctgggtt atatcgtaca gctccaatat ggtactgatt gaccatatta ctcaagtaat
     6121 ttttatcacg actagatccc atattaacaa acaattgacc tattttttct tccaaagtca
     6181 tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta tatggttttt
     6241 ttcgtaagtc tacttttata gtcattttct ttctcctcta cttattagta agatttttcc
     6301 aaaaagtatc tataaatttt tgttcaatat ctacatactc tcccgataaa catttaaata
     6361 aaacatcagt tcttaagttt tcccatgatt ctttttcttt attaaccaaa ataggataaa
     6421 agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca atcattaata
     6481 tcttatccaa atcacaacca ttttcaatta cacttcgaat aatgtcttct ttttttcctt
     6541 tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc cattcttctt
     6601 gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt ttcagagctt
     6661 ttatagtatc tctagcactt aaaaagggtt tatctaatcc tttagcttga ctaatctgtt
     6721 gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga taatattcta
     6781 tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag tgctttaatc
     6841 gattaatgga tgttacatca tttttttcta atgttttaac taaacctaaa aatctgttta
     6901 ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat ttttctctat
     6961 gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt ttataagtca
     7021 tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc atatttctct
     7081 cctatttata tttttgtttt aaaagctcgc aattttctaa gactttatct ttagataatg
     7141 gataaaggaa aaataaaatt aatcctacaa taaaaaaaca aattgatgga attaatgttg
     7201 aagcgttata taacttttct aaaacatctc ccgtttgtat atttgctaaa gagtcatagc
     7261 ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct atttttctag
     7321 caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt acttcttgat
     7381 catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc aaacccatat
     7441 agccaaccga actaagaatt aagaatacat acatattact agtttttatc aaaaataaga
     7501 tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt tttccatatt
     7561 ttttacttaa aaacaaagtt aaaggtgaaa caactattaa aaccaaaata ggattgataa
     7621 aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca taattattca
     7681 tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt atagaaagta
     7741 atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg aattgagatt
     7801 ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa ataagtgcac
     7861 atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact atttgagcgc
     7921 ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgatc aaacttgcta
     7981 aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta atagaagtaa
     8041 tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata ctcccccata
     8101 atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa atcatagaag
     8161 tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa atccacggtt
     8221 taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata gttacatcag
     8281 taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct ccgcttatcc
     8341 ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa gtaaaatcgt
     8401 ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt ctttccatac
     8461 aattctctcc cttcttttgt taagcgtttt cattcttatg aaagtacgta ctatactctg
     8521 aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt ttttctccta
     8581 ataattcttt atctcataaa acttatctat atatttacta gctactcgac ttacttcttc
     8641 aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg caacaactcc
     8701 tacttcaaac caatcttcta agttctctag acttactccg ccagtaggca ttatatttac
     8761 gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag aacctgggaa
     8821 tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa ttgtcataca
     8881 acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc gatcaaaaga
     8941 tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa acgcatctaa
     9001 aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag caatttcttt
     9061 gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa ttccacccgc
     9121 aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta caaccgcaat
     9181 cactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta tctcctctat
     9241 ctccttcttt tatggataca tactttgtct agctgtacta acttaaaaag aataaattta
     9301 agcttttatt tcaagtatta ttttctactt ccgatttcaa aaaaattaaa ataattatac
     9361 gcattacgat aacaaatatt ctccactatc tgactaagat acatttcatc atctggaatt
     9421 cggcctgctt taacccactc gcttagtaat tgacataata ctcgacgaaa atactcatgg
     9481 cgaggatagc ttagaaaact tcgagaatca gtcaacatac ctgtaaaatt cgataacaaa
     9541 ctttgttgcg ccatcgtagt caactgttga cgcattcctt cagctgtatc attgaaccac
     9601 caagcacatc ccaattggat tttttgaatc ataccccctt ggaagctttg cattgctgtt
     9661 gctagtggaa gccaatcagt tggatttaat gaatataaaa ttgtttttgg taagcaccca
     9721 ctcttttcag cggtatcgaa caatgctaca acattttgtg tcaaactagc ttgatccccc
     9781 atcgaatcac caccgacatc tactccaatt tgttccttta atatacttga attatttctt
     9841 aaagcattta aatgcatttg catcgtccaa ccatatcttg tatactcaga catcaaatgt
     9901 aattgaatac ctgtaacaaa ttgtgcaatt tctgataaat ggaaatccgt ttttcctgct
     9961 aaagctttta ttaacagatt gtcgagtatt ttttcatctg ctatttcata aaaataagta
    10021 ttcaaaccgt gatctgctaa tcgacagcca atttgatgaa aatgatccac tcgttggctc
    10081 aatgcttgct tcaacccatt aaagtctttg attggtatag ccgctgcttg actaagtttt
    10141 aaaatatagt tcgaaaagcc tgatgatttg atactccaga ccttatctgg acggaaagta
    10201 ggtaatacct tgaaagaatt atcctgttta gaaagctcag tatgataccc caagtcatct
    10261 gtaggatcat ccgttgtaca gatggctttc acatccatca tctccaacaa ttctttcggg
    10321 cgataggaat ccgtttggat tttttcgtta gcacgtcgcc aaatttctgg tgcattcttc
    10381 tcagaaattg tcaaatcaat atcaaagtaa cgttgtaatt ccaaatgaga ccattcaaaa
    10441 ataggattac ctggcgcctt ctccactgtt tttacaaaag ctaaaaattt ttcataatca
    10501 tcacctggac cactgatcaa ctcttcttct ataccattag ctcgcatcaa tcgccattta
    10561 taatgatctc cagctccttt atcatttaac catacctgag tcaaattctt gtattgctta
    10621 ttttctagca aatatgctgg gtctaaatga caatgatagt cgataattgg ttggtgtttt
    10681 gcaaatttat gaaaaagtct tttagctatt tcattctcta ataaaaagtt cttatctaaa
    10741 aacatattta aacactcctt tccttccgtt agtttttaga agagaaaatt tttcctctaa
    10801 ataaactcca ttatataatt atttactcgc ccccttttca agcgcttccc aaataccatt
    10861 taaataaact gcacctagag ctcggtcata taatccataa ccaggtctac cggtttctcc
    10921 ccaaatcatc cgaccatgat ctggacgaat atagccatta aatccattat cgtacattgt
    10981 ttttaatatc ttatacatat ctagagaacc atattctgat ttatgcggcg cttcgtaaaa
    11041 atcgagtcca ttgtcactta aatatttgat attacgaaca tgtgcaaaag gaatccgatc
    11101 ccgttgacaa aattcagata gaatttcata gacatcatta tctggtcgtt ctgcaatact
    11161 tccagtacat aatgtaatac cattagaagg agaatccact acattacaca accaatctaa
    11221 atcgtcacga tttttaacaa tacgaggtaa tccgaaaatg gaatatggtg gatcatctgg
    11281 gtgaactgcc attttaatcc caacttcttc acatgtcggg ataattgctt tgagaaaata
    11341 tgcaaagttc tctcgtaatt tctcttcatc aacttcttta taggcttcta ataattgctt
    11401 aatttgtgat aaccgatgag gttcccaacc cggcaattca aaattattag tagaattttc
    11461 tacttttcta ataatttcct ccggatcagt agggatattt tttgaaatat aggctaacgt
    11521 agaagaccca tcatctaaac gataatccaa atccgatttt acccaatcaa atactggcat
    11581 aaaattataa cagataacct caatcccaaa ttctgccaaa ttgcgaatcg tctgtttata
    11641 attctcaatg tattgatctc gtgtttgtaa accaattttg atatcatcat gaacattaac
    11701 actctcaata actttcaagg taagtccatt ggcttcgact tcatctttta aagatttaat
    11761 tcgttctctc ggccaaacct ctccggctgg tatatccatt aatgttccaa caattccttt
    11821 cattgctggg atctgacgaa tttcttgtag tgagattttt tcttcatttg ccccatacca
    11881 tctaaaagtc atttccatag ttactttcct ccaacttctg ttatatattt attgattgtt
    11941 ttacgaactg cttgaggacc tactagcatt tcgcaaaaga ttttttcagt tttctttcct
    12001 accccaactt gatataaatc taaaccaaaa atttctttat tttctaaaat ttcctgtacc
    12061 gcacaatgaa tatttgaagg atcttgttca cctaatttca atactgataa tttatcctgc
    12121 aactctacca ataacggatc aggacttggc acaaaatttt ccccttgatc atcgactgcc
    12181 agtaaataac gtaaccaagc agcaatagcg ataggaataa atgttagatt ttctgcattt
    12241 ccgtcttttt cgacatactt tttaattgtt tcaccatagc gaatcgctac tttttgagaa
    12301 gtatctgttg caattcgttg tggtgtatct ggaatatagg gattaggcaa acgtttatta
    12361 attacttcat caataaattg ttttggatca ataatgcctg gattttcaac tactggtaaa
    12421 ccttctaaat aacctattcc tttgattaaa ccaaccaaat catcatcctg catctctgct
    12481 gaaattgatt gatatcctag cagacaacct gttactgcca aagcagtatg aagtggattc
    12541 aagcttgtcg taaccttcat gatgtctgct ttatcaaccg tctctctatc tgtcataatc
    12601 acaccagcct tttccaattt aggccggcca tttggaaaac tatcttcaat aactaaataa
    12661 tgaactacct cagtattagt gaaagcagca atattggtat gtttttttgt gtgaatgata
    12721 tctaaatcct cgagccccat catcaataga tcttccttta cattctctga aggatttggc
    12781 gtaattcgat caatcatact ccaaggaaaa gtcacttttt ctttatcctt taaataagca
    12841 ataaattttt cagaaacata tccttctttt tgccaagctt ctgcaatcgt aaaaatacta
    12901 tcttgaaaac gttgaccatt ctgtgagaaa ttatcagtag aaaccatcgc aatcggcaac
    12961 tctccagcat taaatctgct atataacaag gatgttacaa tactcatcgt atgttgagga
    13021 ttgctaggtc cagatttgat atcagctttg actaccgaaa agaattgccc tttagaatct
    13081 tttaaactgt aacctttttc agtaatagta aacgttgtaa actgtaattt aggatcttca
    13141 aaatatttaa ccactctttg atagtccgct atattcttcg gattgcaata taaactatca
    13201 gccgttactg ccaaaagcct ttttttgagt tcaccatctc cactcataac aatttccaaa
    13261 atgtcattgt tgtagtcatg ataagctttt tccactactt cttcatcaaa tgtttcacac
    13321 acaactactc ctgtttctaa ttcattttga tctgctaagc attgagcaat ttctgcatga
    13381 aatcctcgat aaagatttcc tccaccaaaa tgaagccata ctggatgttg ctggccttct
    13441 tgcttaactt ctttgacatc aaaacacggc agtagaatct gcatttcatt gaattcttcg
    13501 atagaatttt gccaattttt aatcgaaacc ataattaacc tccttaaact aatatgttag
    13561 ttttgataca ttttatattt taaaacccgt tgtaaccgtt gtcaatataa aaatggaata
    13621 aacttgcttt ttttctacca tatcagaatt attgtatttt ttattcagaa aaataaaata
    13681 ctccttcttt ttggactgat tttatcgaaa cttatttttt tctttttttc atgtattctt
    13741 ttatttttat aactagtgta ttacttcaaa atttgatatt atatggcatg aacagaatta
    13801 aaatatcagc taaaataaaa gttaaggagc attgagtatg acaattaaaa ctagtctcca
    13861 aaatcaagct taccaatcta ttcgccgaca aattatctat gctgacttag aacctggaaa
    13921 aaaagtatca gaaaaaaaat tagaagaaac actttctatt ggtcgtacac caatacgtga
    13981 agcactgatt caactccgac aacatggtct tgttgataca attcctcaaa gcggaaatta
    14041 tatctcatta attgatttag attcggccaa aaatgctcga tttgtcagag aacatttgga
    14101 acgacaaatt atgttagagt gttgtgccaa aattaataac caaaaaaaac ggattttaga
    14161 aactataatt tcagaacaag aaaaagctgt tagtcaaaaa aatgctcgta gtttttttca
    14221 taatgataat ttattccata aagcttgttt tgaaattgca gagcgagaag aagtatggca
    14281 atggttagaa aataacaata cacacttaga acgatttcgt tggctacgag taaaaacgga
    14341 aggattaaag tgggaaaaaa ttatggaaca acattatcaa ctatttgagg cattaacaaa
    14401 acaagatcca gaagaagcta actttctaac atcgttgcat cttcatttaa tgcttaatga
    14461 gcaaaatatt gttttagcta ctcatccaaa atatttcaaa agtatataac ttttaactct
    14521 ttttaaatta aatgattgtt ctgatcagaa aaatatcgct tgttttctta ttatgtaata
    14581 tatttcataa actattctgc ataacaacta ttgtttgtac tttttacatt ggataactaa
    14641 ttatgactgc tgataacttt tgatattaaa ctagtatctc caatccaaat aaaaaataga
    14701 tatcttgttc atcaaaatta gttcatggat acttaccttc atttacatca ttcagcggtt
    14761 tctcattttc ttttattcta ttatttcatt ttctaataga cttggcttca tttcgcaata
    14821 cttttttaca ataggcatca aattggtgtt gtttagatat ttagttgtag ttttgtgaca
    14881 tgataagtat gctccttttt gtcttttcca ctaatacaac gatcaaaggg tgcttttttc
    14941 aaaaaactag aaaaatcaaa ataagattcg tattttgatt ctatatatcc tgtttcaact
    15001 acatcttata tttcataata gaataaatag ccttttgcat agctgcttaa cttataagaa
    15061 attgcaattt acttcttcaa agtgaaaacg aatatgagta aaataaaatt attcttctta
    15121 cagataatta aaaatagcgc gtaacaaaaa tcggcattca atcacataat taggattgat
    15181 gccgattact tatattctac gtatagtttt agtattcttt ttttatcacc agtaaccaat
    15241 tgagaacagt cctaaagcag aatagtcttt tatctcaaaa cgcttaattt caggcttagg
    15301 aatatgaata atcttttgag tatattcttt ctcttttaat cttactgaag aaataccact
    15361 gcctatcttt tttacaaata tttcatttgg tgtacagact aataaaacaa tatttgtaat
    15421 caatccttgc actaaagaat taaaaggaag actatttaaa acagggtgtg cataactata
    15481 acatgtgaag tagttatttt gaactttaac ttttaaaaac tttaaaaata atcttatttg
    15541 ttcttctaaa caatcatcta tactcatata atcactccac taattacttc ccccaacaag
    15601 aaatagcatt aatagctata ccagctgcaa tagttgcagc attgaatttt gcaaattgtg
    15661 caggagttaa acttcttttt gctacatcta aaagtatttt aacagcataa tcataatttt
    15721 tcccttgcaa cgcattaatt aaagtttgca ttagattttc acgattaagt atatcccaaa
    15781 caacacacca aatggtaatg agttcataac aacacatgca gcatactttt gaagatcacg
    15841 tttttgacgc tttcctgttg gctgcacaaa attttctaaa ataaatttcc ctgctatacc
    15901 ttcagagcca tctaattcag cttttttctg tatagcttct aaatcagtaa ctatatattg
    15961 atgtgtttct gtatcaacat aaccagcttc ttctaaatag aatttcaaac tctctactgc
    16021 ctgttgtctt tgtgtttcta tatcaggaac ttcattcact ttttcagcag cataaacact
    16081 ggttccggca ccgactaacg tacttaatcc aattaacatt acacctaata atgaaaaaaa
    16141 cttaaaaaaa cgactcattt ttatccctcc tgaaaagtat tgttgattat caatttttat
    16201 ccttttaagc tgttcaataa gacgttttta cgttccttcc gtttctattt tattctttct
    16261 gtcttataac agcttttttc aagtaaagaa cgatataatt cttcttaaaa aacagtctat
    16321 tttttcggta tataataaaa ttgtattgtt acctacatag cgaaacagta ccaacatcat
    16381 tcaaatgaag atagcaaatt tgcttcttcc tttttcttaa gtgactattt aaataaccag
    16441 aaaaaaacta aaatcacact gatatcccaa ataaattgaa ataaaggaaa aagttttttt
    16501 ctaccatgat agtttttcaa aaaatagaaa ctcgtactat ttaaaagtaa aataactagc
    16561 atcgtaaaga ctactgattt atctaaactt ctataaaaaa gtgggctaaa taataaagta
    16621 attaaaaaat gaactatttg atattgtttt ttttcatatt aacagatcgc agctcctgcg
    16681 attccatagg ctgttcctac agcaaatgga ataacggctg cacctactcc cgtaaggctt
    16741 aaacctagag cagcagctgt ataaatccca gaatgtagaa gtccagcccc agtgaaagcc
    16801 caactgcagg cacttcgttc accagtttta ttatttgttt tttgatcttt catataattc
    16861 tcaacttcat gaagctgatc ggttagccat ccatggccat tttttttgaa tagaacgatt
    16921 aaattcattt agatactgtt ggatttcaga aactgtaatt tcagaattaa ttctatctaa
    16981 acttgatttt aaatcactct catcaataat atatactaat cgatttcctt tagaatcttt
    17041 atgtgtggct aaattatttt gaatgatatt tatttcagtt tcttgttgtt ttactaaaaa
    17101 attatttgtt tcagaagcat cgacacttat tccagcgcta acaaaagtac ttaaacctat
    17161 taagaaaaca cctaaaatac caaatatttt aactattctt ttcataattt ttcctactta
    17221 aaaataagtt atttttaaaa tatcttgatt atgaattcat cccccaaagg ccttttaaga
    17281 ttgatacagc agtccgttca cttcttttag acttgtcata taagtctttt aaatgatccc
    17341 ataccagact agtttgtcta tctagcttca atccattaaa cgctaatgaa cggttcattt
    17401 tttctattac tttagataaa gctacagaaa tttttatacc ttcacaacgc gcatcttgga
    17461 tttcaataat agtatcatca attagttttt gaatttcttt cctatcaaca tattcaatct
    17521 tagaaagaga atcttttaaa gctactaatg attcaacgat ttcttttttc tcttcagaca
    17581 ttctcttcct ccttctagtg acccgtaaag ccatgtagag cagagtccat tgaaccagta
    17641 attacactat ctacaacgcc attccaattt actctacatt ttccattttt cagatttgtc
    17701 ggtccatacg gatagacttt ttgacattca atgttcggat tataccagat aggattatac
    17761 cattcagccg cagaagcaga ttcagtcgat acaaacaatc ccacaccaac aaaaccaata
    17821 cacatcacac tatagccaat taattttttc atctcgtatc catctcctaa aaaatagaat
    17881 agttcttgta gttattcata agacatattt tttccgtttt tgttttatcc tttctgtcct
    17941 ataacaactt ttttcaagta aagaatgaca tacttcttct taaaaaaaca gtctgttttt
    18001 ttctattttt tcggtgcata ataaatatga gtgttcattt tttattttaa tacacacttc
    18061 gtacataata aatcttgatc gcatcaatct tttgagcttc ttgatctact ttcaattgaa
    18121 gtaatacaaa ttgagtgacc tcattcgttg tttcttctcc aaataacaaa tattgatccg
    18181 gattctctat atcttgtgtc acctggtgaa gtttcccagt tgttttcatt tgtacatgcg
    18241 ggtctacatc aatactattg tctttaatac aacgatccgt catatagtcc ctcacagctt
    18301 gattgcgttt ataaacatct gtgaaattac tccattttct agcaaaatct tttaagaaat
    18361 tttttgtcat ttcatctatt tgttgcgctg tctcgtcttc taatgaacca atttgactgt
    18421 tactttcagt actttgaaga gttccacttg tttcttttac tgcttcgatt gtttcttctg
    18481 tcgttgtcaa ttgtgttttt tgtttttcag aagaaaacca atgacaacca gtaagaccta
    18541 tcaaacataa ccaactaaat actaaaatta ttcctttttt cacgcttcta gacactgcct
    18601 ttcttatttc accttacgaa ccagactacg aatttttgtt tgattgtacg tgcgttgata
    18661 ccgagccata atccgtcctt gctcggcatt ctgttccaca ctagagaaat gttgtccgcc
    18721 atctgaaaca tctgttataa ttccggtgtg accatagatt ccaggagaca atgcaccacc
    18781 tgcttgccaa ttcaccacat ctcctgcttg taaatcactt ggttttgggt tcatgatcac
    18841 ttgccaacca taggctgtcc aatcataatc ttcccctatt aacatcgcaa acatgtgtcc
    18901 agaacccatt aactgtgggc cacctagttg ggatacatac cacgccgtgc caccataaca
    18961 ctctccatta tttaccgatc gtccaatgat ccgatctaaa actttcgcat tacctttact
    19021 tttccctgca acaagtgacg atttttttgt tggtaggcta ttccaatgtt tgatcgcaaa
    19081 agtatcatat tctgttaagt tataagactt tatgatactc atcgctcctt ggtaatacgg
    19141 actgccttcg gtaatacctg ccgccgcata gcctccacga cctagaatca ataaacaact
    19201 cccaggatct ttattgccca cacattgatt aaagttgctt tgactcgcca ccaaaaagcc
    19261 gtaatagtca taacaatctt tcaggttcgg aaacttcata tagaagccac cttcagaacc
    19321 accaatcccc cgtgcagaac cttgtggata gggacaacca ggaaaccagg taatcccaaa
    19381 gaagtttgta tcgtttcttc cagattgtga ttgtccataa gtcgattcat aacctaattg
    19441 agaaagaatc acacttggta ataactgata ctttaccgct gcaccgactg ctgcttgcgc
    19501 atgttcatct gtgatcggac cacgtccttt aatctctgaa aaaatcggta atccttcggt
    19561 atattcccaa ttaaaagcga cagctagacc tgtagcctct cctccatcct cggaaagttc
    19621 tcctgaaaaa aagaatggca atagaaaaaa gggaagaata aagaaaagca gacaacctag
    19681 acaccctttc ttcatttctt cctcatcctt tcttcgataa tggtttttga actgttcgtc
    19741 cttttggtaa agtaaaatcg gttcctggtt ttgcgtccaa aatcggcaat gtttcatttt
    19801 tcttttctat ttttttcgat tgctctactg gattattaaa agaagaaaat gcaggttgta
    19861 aggattttgg tacggaaatc gacggtttac tttcagacga acgttgtatc tgtcgttgca
    19921 cagaacgatt tcctgataga gtggctaccg acgacttagg aacagagtat tgattcaata
    19981 actgctgcat tgctggataa ctcccatttt tcgcctgatt tttcacttgg tgaatctgtt
    20041 gtgaaagaga accagcagct gttaattgtg gcacgggtac ttttccagca ggcaacggaa
    20101 tcgattgacc aacaaaagcg atacctttat ttaacaatgg ttttctttga ttattccctt
    20161 gttgcttact cgattgtgcc aacgattgta cctgttgttt cggtcttact gaattcatgg
    20221 acgaatttgg aatcaaacca tttgaaagac cagaattcca ctctgttttt gatttggtag
    20281 aagacatttc aggctctacc ccatgataac gaacatgacg accactataa ggcaagtctt
    20341 gatttgaacg cccacctagt tcaaagggat taatcacttg cccccctttt accgattctt
    20401 gtggtgtacg tttttgttga aacttttgaa atccatgtat cgctgcagaa gcgagtggat
    20461 tcgttgctcg gtacacattc cctgctaatc ctgcaccttt gattgccaaa ttttgcccag
    20521 cagttgatag ttgaccaggc agttgtttca tttgagacaa agaatgactt gctatgtttt
    20581 tcgtgttatt tatggtttga tctgcagctc ctaaccctag tttctttaat aaatctttcc
    20641 gttttacaat gagtaaaatt gataggagtg ctttgacaaa catatttcct aaaaaaccaa
    20701 aaacagtatt cattagaatt aaatcgtcta ctatgttata gatcaaaaat gccaccaaaa
    20761 taatcacact gtaaaaagat ttttgaaaca tcaagctcaa aaaggacttt aaggtattca
    20821 tgatcatata atcaaatgct ggaacaaaag aagcgagtaa tgaaaaagga atcacaagta
    20881 ataaacacaa caccaacatt tgaaagataa aacgaatcat gccaatcact acaagtggta
    20941 atccaatacc tagattaagc aatggcacca tagaaccaac gactgcttta taaacagctt
    21001 tagttggttg aatatagaca cgataagcct tctttttccc tctatcttct cctgcagcag
    21061 tggtcacttt tgtctcaata tcagataatt cttcacttga cgcttccttg gctagaaatt
    21121 cttgtggttc aatctctgct tgatacaatt cttctaaatt tgttgtccca taatttaaca
    21181 atagatacgg atcaacaaca gccgctttat aataaagttg gcgcactttt tgaatggctt
    21241 ccttttgtgt cgttggcact aaaacaccat tgacatcttt tgtcgccaat tcatctagac
    21301 tatttgtagc agaaaaaata aagccttcta cctccacgga caaatcattt aaccctttag
    21361 taaaagcttc tcctttacta ggtacgttac taccatagcc aaaccaaacc attgaaaaaa
    21421 tgacaacaaa gagaaatcga ataaacacca tttttgcgta atgtttccct ctaaatatac
    21481 gaagagtaaa tagatataac acatacaaga cgacaatccc cgcaccaata ggatcgtata
    21541 ttttcgaata aatagtatcc gaaaaagtga aaaactggtg aattaactcg ttcattgcag
    21601 ctccttcata gagcttctca atgacaaaat caaggccttg ccaaatcaat ttacttaaac
    21661 taaagaacat attcgtcatc atttttagaa aatctgtgcc atttgctcca aataacattt
    21721 tgcctaatga aaattcacta tcagataaat aagaagaaaa ggtatcaata tgaaatttcc
    21781 cgatctcata gatcgattga tccacctgtt tttctaccgc atataccaat ccaccaacaa
    21841 aaaacagtcc gaatccaacc gttaaaaaaa gccaaacgca ccatttcttt tccttacgct
    21901 ttatataagc cattgtttca cctcgtttct attgcatgat taacgtatcc tgttcttcta
    21961 tttgagagtg acttgttttt tccgttgttt gtaatgcagc ggtcatttct tcaaacaaac
    22021 tgtgtacatt gagttttcct acacgtccat agggatctaa catccaacac tgtcctttaa
    22081 tcatatggct catttcagat aagttcgctt catttacttc caaacgtaaa tgagtcaaaa
    22141 tcttttctcg ctcactgtct tcatcaaaag cgaagacaac accaaaattc cctttttctt
    22201 tatctgaacc taagtcgcca ataaattgtg tatctagcac taattgattc atctgtgaac
    22261 gccccacacg cgccattgct gcaataatac tacgtcccgc gttcgaatta ttaaataccc
    22321 atgcttctgt aaaataaatc gctgttttct tactactatc tcgttttcca aacatttcac
    22381 aaaaacgacc taaactaatc atcaaacaca aagactttcg atccgcatct gtatatagtt
    22441 ctggtcggac attgtcattt ggtaatttca aatcttggat ctctaaaatc gttgttttgg
    22501 cattaaagtc taatcccggg ttttctccat aagaaaatcc taaacgtaaa atcgaatctt
    22561 ctaccgtcaa gcgtaaaaac tcaccatatt ctcgaacctc tttttgttcc atttgttcta
    22621 aatactcgac cacatgcatc aagccaactt gttgtccggc ttctttttga actaaaactt
    22681 cttggattcc ctttaatacc gcccctttta aaaggtgatt ggtacctaac ggacttaact
    22741 catcaatcat atcctgggct acttgtttcg catctactcg ggataaacaa acaattggat
    22801 ctaatacgcc ataattacgg ggatttgtag catctaacgt gacataactc attttttgca
    22861 aatgttccac aaacaaaggg taatgtttct gataatacgg gtcttgaatg agtttcgtaa
    22921 accatttgcg cttttctcct ttgggatcca caaataaact ttgtacattc ataaacgaac
    22981 tatacaaaaa gagcaatcca actaaaaagg tcttcccttt accggttttt ccagttactg
    23041 ctacatgagg cgcatcaaac aacgcacctt tgattccttc cgcaatagct agaagattca
    23101 aaaagacaaa acgatttgac gcataaatta attcttctaa tggtgttttt tctcctcgag
    23161 aaccaccatc ccctaatgta tcttgccgac caatatacca gccggattcc atacctaatt
    23221 ctgatactgc tgaaaacaac cattcgccaa ttgcttctac agttgttcgg tgcttccaat
    23281 gcaactgtcg acccaatggt tgccctaata aacatttata gaacaattct cgttgatcat
    23341 tttttgcacg gtggatatgg atagtcgtat gaagctgttg aataatcgtt gcactatttt
    23401 gacgaacttc ttcaaccgtt tgaccgtata caataaaaca tgcgatccaa tcgacgacag
    23461 gttggccatt atctactcgt tgctttaaat gttttactaa tccccgaaca gttaataagc
    23521 gttcgctagg ttcttcatcg ttttgaacca attccttata ttctgttttg aaccgttccg
    23581 atagccaatt tagttttaaa ccaatacctc cctgtccttt caagcgtgga tagtgaattt
    23641 tcattcgtaa ttctgctggg aaagaaagat cctgtgcaaa ttgaaataga tcacagtttc
    23701 tcatattttc aggtgtttct ccaataggta acaacgctaa ataactagtc cccaactcat
    23761 cttctaattg aagaaggcct ttatgttcct tcggcatacg tacatacgtt ccttgattgt
    23821 ctttcagtac ttcccaatta ttttgttctt ctactttatg agccattcct cgaatatatt
    23881 gcagacgatt gagatacaac agctcttttt ttactaaggg acgaatagaa aagctataaa
    23941 gtaattgtgt cacttctttt acataaggat cactttcaga aaacaaagtt tctaaatcat
    24001 ctacttctaa tccaaataag cgtgctaaac ttcctgctac atctaaccag attagattta
    24061 gtacatcata aaaactctcc acggttgctt tttctttgac tttgattcct aaaataaagg
    24121 aaggacgata gacttgacct tctcgttcca acaatgtcac tgtttctttt gcataatacg
    24181 caccaattgc ttgactatcg ggagaaaatc cctttcctaa tgtgtcaaat ttcgtccgta
    24241 aattcattgt tcgtggatac atcaccaact ccacatcttc ataatctgct aaaagtaaca
    24301 gtaaacgagc catcatttct tttatttcct gtgtcttttt tggtgtgttt tttgaaatgg
    24361 ttcgtggaaa aacatgatag taggcccaga tacaatcctc gccatttaac aaacaatttt
    24421 tctttaatgc tttcactggt tcttttacaa gtaccaatag atctcacctc ccaattaaaa
    24481 aaaggaacaa ccagttgatt gtcccttttt ctaatcctct aaataaacat acttattcgc
    24541 aaaaagtaat tcttccaatg cattatttga taccttgtcc cagttataat acacacaatc
    24601 accattcatc atacgcacta cataacaaaa ccaatcccat aaataaaaat gcactttttt
    24661 tccatcaggt tttagttttg ccagtgctaa cacacataaa tagggtagcc ctataaaaaa
    24721 aacaacccct gctggtggaa aaaaagaaat aacccaacca ataaatgaac gtaaaaataa
    24781 atattcaaag attacgacca ataaaaaagt tgctgcattg actaatgcaa ctggaaatgg
    24841 aagacgccaa ttgcttgtaa tctgttgtac gcgataaggc tccgcataaa caatcgaata
    24901 atcgtaaggt tcccaatcca cttcactatc ctcctaatcc ataaataatt tttcaatgat
    24961 tttaccaaac gcatcaaata cacgcgttgg atcatttaag aagaaataga ctgcggcacc
    25021 tgctgcgata gatattaatg catttcctac ttttgatttc ataaaatttc gcaatcccag
    25081 ataaacaacc accattatta aaaaatagcc accttgcgtt aatataaaat ctacaattcc
    25141 cttcagtgtc atttccgttc gtctcctttc ctatccaacc aattatgtgt gagtttttca
    25201 acataatact gatttgtttt tttcgtaata acaagcgtca tttgttcttt ttgtaaaagt
    25261 gacgtatcac catctcgaaa gacgactgtt gcttttacaa taaaagtttt tttcgtttct
    25321 ttataacgca atactttcat ctctacttga tcaactttag ctgtctgatt gagtccttca
    25381 ggttctttca tcatgtatga catatctttt gcattgtttt tcgcatactt atctaagaaa
    25441 tcttccacaa atccttccac atctttcgct tccgacgcat caaccgtttc gtataatgtg
    25501 tcatcataag taatcattcg ttgtttttct gtattctttg gtagtgccgt aaaataagga
    25561 taagcaataa tacgacagcc cttgtttgaa atagaaaagg gaagattgag tacttgtgtg
    25621 attgtcacac ttgtttcttt cttattctct ggatccatcg agcgaatatc ataagttact
    25681 ttataactag ctgttggaat ggtttcaatt tcttttaatc caataaacga agcagcagtt
    25741 aattttcgaa tacctgaaac acttcctggt tcttgaataa agttttgtgc ataaaactct
    25801 ttttttaata tttcttgacg ttgttgttct tgttcatgat tatcgaatgt attcatatac
    25861 aaagcaacaa aacgattcat aaaggattca atttcaggtg tgtacgttaa ttctgactga
    25921 ctttgtactt ctttcttttg taattgttgg atttcatctt tcaaaaacga cacttgaacc
    25981 ttcgttttca tggattgaaa aaatgccaag ccccctgaaa aacaaagaaa taaaaccaaa
    26041 caccaaatcc atttcactgc tttttttgaa tggattttcc tttgattcgg tactttctct
    26101 gtataaactt tttctttccg ccgtagttgt cgttttttca taagctactc cttctagtat
    26161 gtttttacta gtacgtacga ttgacaacga taagcttgtt tttctgaaaa atagtccatt
    26221 caattaccct cattttctat tccttttctc tttcttttat atccaacaaa tccagcaata
    26281 cttgtcaaca ctcctcctag aacagaaagt acaacatgta tttcttcacc agtctttggt
    26341 aagacttttg tttttccatc tgctgttttg acttcaatat tgccacttgg aagtttcttt
    26401 acaggaatcg acaaatcctt taccaaattc ccttcactat cttggattaa tggaattcca
    26461 tcttttacac caacaattgt ttgtccacct tctgctttta gtggagttgt tggtgttgga
    26521 atatgggtca attcctctac attactagtg acaatcggta cactcattcc ttgagaatta
    26581 ttcgtcgtaa tttcaccgtt tggggttacc gatactgtga cttcttttgc tggaacaata
    26641 ggtttatttt cttttggaat tgcttctgat ttttcagcag gttgtttcgg ttcttctttt
    26701 ggttcttcac tggtaaacga catcgttggc tgttccgtac ttgacgaatc ggtattcgtt
    26761 tcagaagaac tggttgttcc tgattgttct ggagttgtga ctatacttga atccgttgtt
    26821 gttgaactgt gcacaccttc ttcttcaatt ggatcagtcg gcaaagttga ttcaggaatc
    26881 tctggttctg gtgccactgg ctctttttca ggtttctctg gctgcaaatg ttcaggttct
    26941 gctggttttt ccgttgttcc tccatttagc tctgtctcaa catctgataa tccttcccct
    27001 ggcaatgttt ctacaatttc tgacttaggt gtttctacag tttcatctgc ataaaccaat
    27061 gaactcccta attgaaacga aaataatgaa attcctagtg ttgttacgac tgctaatgtt
    27121 gtttttttca tgattattcc tccaattttt tatgcaattc gtgttttgtt catagacgcc
    27181 gcactaatat tatctgaacg ataaaagaac tcccgtccgt tttcttctaa cccaacatat
    27241 ggattatttt tgaataattg aatcaatagt tcactggtgt tgtattttgg atagtttgca
    27301 aaaaaataat actgtgcttg tcgcccatcc gaaaattcaa caagtaattc ataacgatac
    27361 cgcttcaatc cttttcgttg ttttaaagga tctctatacc aacttgtcca tcgttccgtt
    27421 cgtggaccga gatagacacg atacacatag aacaatgcca taccacatac caccaaaaat
    27481 aataatcgcc acataaaaat tccccctttt cttctacctt tcttgaatca ccgaacattc
    27541 ataccctcgg tagagatccg aaaaatccat cattaatttt tcgtataaac gttgttgcaa
    27601 atagcgattg tttcgaatac ataattcttc atagccatca atcacttgat cttctttctc
    27661 atagcatctt gtagctctat gacgctcagc ttgcatgaca taaccaaact ctgcaccata
    27721 tcgttctacc gttaataact gttgactacg caataatgca atataacaat cacaaaaatg
    27781 ttcagccgac atttgatttt tctcacgttt gtgaaatagg tattctttag aaagcacatt
    27841 attcgttaaa caatctgata aatagcgata atctggcggt cggttatttt catctgtgaa
    27901 tttttcccat aataaactga tttttattcg ttcagcggct agatagtctt gttcgcgtgg
    27961 ataaaattca tcaatcgtac aaagcttttt tatcacccga ataaacaaat ccatataatg
    28021 cgaaacgaac tcttcctttt caattggctc tcctaaaaat tccagtgaca taccatcttc
    28081 tccttcctta aaaaataaaa aagcagaaac cgatttggct tctacttttc tttcctttta
    28141 tagctctttt ttacggaaga atccgcaaat gacatttttt caaaaaatta atcggcacaa
    28201 gttcacgaaa acttggagca attttagata gaatcacttc cccatcttgt aaaatacaat
    28261 cataaaaatc atcagttact tgatacttac gcttcttaca ataattgata aaatagtagc
    28321 gatcattttc tatttccatt cgttgttcta ctaagcgcat acgaacatca tcatagaaat
    28381 aagccacaaa tcgcccttca agttcacgtt tttcaatggg atactctttt ggtaacaatc
    28441 tattttttcg tcgtttatac attgctggat accttagaag aagttcatcc aaacgtctgt
    28501 cagtatatgg caactgacga atcaatgatt ccaatcgttc tttatacaga tagaataatt
    28561 ggcgcaagca atagtgtact gcttctggat tttctaatac tgttggatca cgcgaccaat
    28621 acgcaccaac ataaatcata atttttttca tttagacaat cacaccagca atactaatca
    28681 ccgatccaca ataggtagaa caagtggcat agcggccgat ttcctctaat tccagctcaa
    28741 tctcttctaa agaaagatac gtctgttctt ctgttggctg gcgattcatt tcccaagtaa
    28801 cagttgccaa cgagatttct tccacaagag gtttttcgtt gctaagtgct gccacacagt
    28861 tttcgtatat cttcatttta tcgcagcctt tttttaccgc taaaatcgca ggtaccggca
    28921 atgaaaatcg ataaaagcga atgaatttta gcgttccttt tcttcggcta aattccaact
    28981 cttcgagttc ttgttcgtac cccttacgaa cttctaataa gcgtgcaatt tcttgccagt
    29041 tttctttttc ctgataacgt ccagccttta ccgcttgttc aatataagga actcgaaaac
    29101 gaaaataaga caaatcaacc atcttttcat ttaatgcttc aattgcagcc tttaaatcca
    29161 aaagacgcag ccattctgtt gtcgtatatg cattcatgca attttccctc ctgacgttcc
    29221 catccattct agatagcttt gttgctcgtc atttagttca gcattctcaa ttccttcttg
    29281 tacaaagtct cttcctaaaa tacgatctgc ttcttgtaat aactttaatg tcggagctac
    29341 ttgtttcaaa aaccagcgtt ctgaacgatc taatgagaat ttttctggct ttacggtaaa
    29401 atccaattct tccatcgaac gaaacaattt tgcccatcgt tcatcaacaa ttcgtgcatc
    29461 actttccagt cgatcccaaa caataagttt tgcattaatt aaaccaacgc caatctctcc
    29521 taaacgttta ggggaatgat ccaaaataaa cgcttctact gcttgtgttg ctttttcatt
    29581 agctaggcgt aactcatatc gattataaat gccatatttc gttaatgctt ctatttctga
    29641 aattttctca cgattcgcaa tttcaaaacg tttttcgtag aaattgaaaa acaatggact
    29701 ctttcgcgat ccaaaataca aggataaccc ttcgcttcgg aaataaccat catctaaaaa
    29761 acaaccgcca atattctgaa atttcttaaa gtccatttct aataaacctg ctttttgttt
    29821 ttctagtaat tcaaagagat caaaatgttc ttctgtttcc aatccccaaa gttcatctaa
    29881 cgcaatatcg aatcgactac attgtactcg tttataacca gcttccaact ttccttgatt
    29941 tttccaaatg gaatatagcc atgttcgcca atctgttcgt tgttcacgca tgacttcctc
    30001 atattctcgg caaccttgac ccgaaaactg tacaagtaca ttttgtgtta cagtttgttt
    30061 tgaatgccag aatacccaga tatttccacg aacagaaaga caatcaaaaa gatacaagcc
    30121 cgtcggacgt gtttcaaatt ctgttagatc cattcgtaac acacgttgaa tcactatttt
    30181 gtagtctgtc ccaaaaaagg agagacgcaa atagtcgatc attgctcgaa gatctattcc
    30241 gcttttcata tacaatcgaa agcgttcctt gattcgtttt tcgaaatcct ctgggatttt
    30301 cttttttcct tgttccatct tctttatata atctaccgag catcccaata actgtgcaaa
    30361 acgtttttga gagagtaatt ttttccctcc acctgaagcg tgaatagcac tcaatttttt
    30421 tcgataattt cgcaattcaa taggtgtcat attctacctc ctttataaaa taacaaattt
    30481 cgattttctt aatctgctag aaatcccgat ataacaggtg gtacccccta atttttctaa
    30541 aaaggagtac tccttctaac cttagctaaa gccttgatat aactgattta aatacacttt
    30601 tttatttgtg ttatgttatt tctgcccccc atattatata tcggggggct ttacacaaag
    30661 aggccgtgcg caagcgcacg acctctttgt gggcacacat gccaagcatg tgctgccacg
    30721 actggtctcg gtggcttcgc cgacacaagc cgcggcagca catactcgga caatgtgttc
    30781 tcccatagtc cctatgaaag ccaccccgat atctaaacca atgaatcttc tttttcttgt
    30841 aattctttat actgttcagg agcaaaacac tgtaaaatcg ctaaacgtaa ctgtatgttt
    30901 ttctctttgc ataaccgata tacctgacga aaacgcaata tatcctcttt tgtcaaaaca
    30961 atctgatttc tcgtaacaaa caatgtctcg cgctcaattc gtcggaaaac ataagaacct
    31021 tttgtgtagt attctacttt gttaatccac tcgtataatc ttcgaaccgc aaaatcaggt
    31081 gaaatttcac ccgcagctga agaaacacga tacaaaactt cacccatact tcaccacttc
    31141 cttctaaatt ataaaagtgt ataactttcc tcatctaccc catttgtttt cgtatttcct
    31201 tttaacgatt gcgcttgacg atcaatttgt tcttcgtaac tagtaaacgc ctcttctttc
    31261 agtacagaaa aatcttgcac aatcattgtg tcaaattttt taaattcctc aataaagtga
    31321 tagtctttgt aaacaaatgg cgcaaagaat tctacaggca catcaaaacc aggaaaagca
    31381 tacccacgac caggttgatc tttgttataa aacggcttat tcttaaaatc ctctccaaaa
    31441 gtcattaaat agccaatggg agataaacgg ccaacagaaa tacggaacgt taaactatct
    31501 cgaacaccac ttggaaaata ttccgcatct ggtcgctgca tcgctaaaat aacatacatg
    31561 cctgcttgac gaccttttaa tactaatggc tgaattaatt tatcaacttt gtttctcgtt
    31621 tccatatcca acgaaccata gaaagctgcc cattcatcaa aaaagataaa atgcggcggt
    31681 atcccataat aagcataatt tttccctggt tcatacttag gctctttcat cgttttcata
    31741 taggtatatc gctgattcat ttcttgtaac gcatttcgta agcaaataat catttcttca
    31801 ttcgttttgt aaaacacatg tcctttgaat acatcaatat cacctaatgc cgctaaatct
    31861 gccgctttcc catcgcaaat atctactgtc cctacatcta aacaagcttt gatcaatgaa
    31921 tacaataaat aggtttttcc gccaccaatc gcaccagaaa ttaatagatt tggcgattga
    31981 tcatataccc aatccaatgt tttcattaaa tgaatacgtc cattttctgc tatacattga
    32041 tcaataggaa tccgaccaga atcggaaaga aatacataat tgattcgggc tttttctcgt
    32101 tcttcacgaa ttaaatcacg caaaaatact tcggataata agctacccat ttttaaaaat
    32161 cgttcgtgga aacggccacc atctaaagga aaagaaacca ctaattcttg tttcttttga
    32221 taaaaataaa cttttggtaa tctcattttt tccttcgttt gtttctcacc aacttgcttc
    32281 tttgtataaa caaaccgatt gtcaattaac attcgagcaa gtaactgacg ccaataaaca
    32341 gaagcaaaat atccttcctt tagtcgcgac caacgcatca aacctaaaat taatccacta
    32401 accagcaaca aatacatcac aatactgatt ccaggaataa gatacatttg ccaattcgaa
    32461 tacgtattta aacgaggata aaatactttc caactaaacc aacttaatag aatcaaaaat
    32521 ggtaacagaa agaaaccata ataacaaaac cataaataac gattgaaata acgaattcgt
    32581 cgaccacgat acttaaaaaa atgaggttcc aattgtcaca ttcctccttt ctgtttttac
    32641 ttctcctgtg ctaaaaattt ttgacaaaaa gcaactaata ctggaatatc acatttaata
    32701 aaaaaccata atcgaaaaag atttaatcga tttttatatg ggtgtgcaca catattacat
    32761 attcgtacta cacgaatcca aaccacttcc tgatggtctt gtttccactg atacggtaat
    32821 gaaaaacgaa caagatcacg taaaaacata cactgcccaa taaccgcaca aatatactca
    32881 tttgtttgta taaaaatcgt tggattgtct ccaaaatact caatcaattg ttggatattt
    32941 tgacaacaaa ccataatctc tcgaagtgtt tgattggttt tgtccagatt caaaatctcc
    33001 ccttccttct accttaaata gaaagagtag gaagacttcc tcctactctt taaaaaactt
    33061 attttttctc tttttcctta gaatcagcac ttggttgttt ttgatctaaa cctttttctt
    33121 gtgattgttt cggattagaa ttatttgttg gagcttctac tttctctaat cctttcgcat
    33181 aaatcactaa atctgaatat tcacgattgc catcttgtgc tggaatatat accacatgat
    33241 attctggatc aattaatttc acaggatcac gtcgtttaaa accagtcaaa tctacatctg
    33301 ctggaaattt aactcgtcgt gcaatctttg gttcatctgg atttccaaaa actaattgtg
    33361 ctcgctgtga tcgaatttct cccgtataat cgcctgtttc attatcaaat acacgatcgg
    33421 actcttctaa tgcgccaaag cgtacggctc ctatacaagt ttcatctaat gcttctgtaa
    33481 tatcataatt atttggaaat tttaatccca tcttacaaaa cctcctcaat ttttacacca
    33541 gttaaaaaga caccgacatc ttgatagcca gttgttcgac gctctgtttg tcccatatca
    33601 tttgtttcac gactattcac tctttcttta cgaaaaacaa aataagcttc ttcaaatgaa
    33661 atacgtacct ctttttctgg taatcgtaat cttttatcct cttcagctgt gagataaaca
    33721 aaaaaagcag gctgttcttc tcgcgaacat tctgcttgta attgaacata tcgcccagac
    33781 acaccattaa tttcctttgg tggattaggt tcccgtgaac ccaataaaaa tacctgacct
    33841 aaaaactctt tcttcatacg caatgctttt tctgccatat catttttcct cctcttaaaa
    33901 ttcacaatca attctaaacg actctatatt acacaatgga aagtaatgtt taacaacaaa
    33961 tggctcatca ctaggagaca tatctactat taacatcccg tctcgttcat gcacagaaat
    34021 atcagtacac tcctcatacg tacattcttt tccactcaaa aaacaaatat ttatattttt
    34081 cttttccata ttcttttttc ctccattatt ttcttttctg taaaaaccaa gtaataattc
    34141 cttttccatc ttccaacaca aactgatgat atatttccct agcaagaatc cacacacatg
    34201 ctaaaataaa gaaaataata atactactaa agatgcactc atccttgctg tcaaacggaa
    34261 aaagatatat cataattgcc tcccccataa ttaagaaacc aattgataca aacaaaaact
    34321 ctaccatcat acaaaagaat atttcttcca actcttttac atcctttcta actttttata
    34381 aaaaaggaga ttatttttat aaacactttt attcaacaac tattttcaaa tgaattacac
    34441 attatcatct caagtatagt ttcaatcgtc actattgttt ggtccatttc tagcttttat
    34501 ttaaaacatc gctatacaag aaaaaagaaa agcactgaaa ccctaacaaa agaaatgttt
    34561 attccattta aatcttcaat tgaaaattat ctatttcaaa aaattacaag aaaaaatatt
    34621 ctagaacgaa aacaaacaat tcaacatcta atccaaacag ttgaaaataa aaatatagac
    34681 ttttatttgc cttatgaact tatttatttt gccaaagaaa tacaaaaaat aattaacaca
    34741 aataaacatt cgaaaaaaat cctcttcaaa gtacaaagaa tgtattttga attctcatac
    34801 tgctacctag cagaactaaa taaagtaaga aagcaattag gagtagctaa acgtgatttc
    34861 ttctatagaa aaaaagaaac tgtattatca cataattata ttctatctct tttggatcct
    34921 taaattctta tttattacac tcagtatttc ttggtgtatc ctcatgatca tttactactc
    34981 aacacaataa tttatttgcc tttgataaaa aattctttct aaaaactaaa caagcggcta
    35041 gttgcctaac cgcttgttcg tcctctttag tctctgactt tatacaaatc ataaccaatc
    35101 aatcctgccg caaggacaaa gatcatacca atcatgatcc ataatacatt gtcttcagag
    35161 cctgtttttg gcaacatagg taccattgca gcttgtttca cttcttttac aggttgtggt
    35221 tcgtttggtt ttactggttg cggtggtttt ggtgcctcca caaattgaac cgtttgatct
    35281 ttgtttgtta gatcgacgtt atgttttgcg acttcttcaa acgtttcttt ttcatcttct
    35341 gttttggctt ggagccattc cgcaaaactc aatccttttc ctgcaaggtt gcgaccgtca
    35401 acgatgaatt caaacaagaa ttccatcatt tctttatcag ccataaagac tttttccgca
    35461 tgtgttcctt caaatggggt gccgtctggt gttaagtagc cttgaacaat cagtttgtaa
    35521 atttgaccga ttgctaaccc attaacttga acccattcga caaccttttg atttggtaaa
    35581 gctaagatct cttttccacc atttgcattg gtagcttttg tcgtaatggt tggactgacg
    35641 attttgatgg tttggtcttt gtcggtaata tctgcgtgag aagccaataa tacgccttct
    35701 ctaaacagat cttcaaaaac tacgacttct ttgcttcgca acgcatgtgc gtctaggata
    35761 aagtctagat tgactgtacc atcagttgtt tctgccacaa acgttaaggt acttgagact
    35821 tcttttccat ctactagcac tggtttttcc gttactttgt ccattagaac accgttgact
    35881 gtgtatgttt ttccaacgat caaatcgtgg tatttcacag cgtctgtaat ggtgactttc
    35941 gttaatggat taacctcttt caagccagtg ggtttatgtg tagccgttgt acgtacactt
    36001 gggttcgtta ctcgtaccgt ttgacctttg tcgttgatgt ctttatggtt tgctagttct
    36061 tcgtcatttc taaaaagact ttcaaacacg accatttcac gaccatttaa acctgtcaaa
    36121 tcaaaggtaa atggtacgat caccgtttca ttttctgctt tggcaataaa gccaacagca
    36181 ctttctaccg gttgaccatg aacaagtaag gcttcaccag ttgctttatc cattaagatt
    36241 cctttgacca agtaagcttt tcctggaagg atctcattaa tttcaacggt atcatttaag
    36301 gtgaacagcc ccgttgggtc tgcgatcgtc aacccgtctt caaatacagc tgtggtatga
    36361 accgttggat tgtttacccg aacactttga ttgtcatcat tgatatccac atgtaccgca
    36421 acttcaatgc catcacggaa aagtttttca aagacaacga ttgtttgacc tttcagaaca
    36481 ctagcattaa ccacaaattc aagatctttt gtgccattgg ctttgtctgc aataaaggtc
    36541 aagatacttg tgatttcttt gccttcttgt aaaattggcg cattcgttgc cttgttcatc
    36601 aatacacctg aaatagtgta ttctttgccg acaaacaggt tggtataaga aacactatct
    36661 ttaatgacga tagtttctaa tggatcaacc actttttcac catcggcttt atttgacgct
    36721 tgtgtttcta attttggtgg aatcaaatag ttacgtacag aaaccaataa cgtttcccca
    36781 tcatctggcg cattttgtct gaatgtaata gtgaatgctt gtttgcctgt atttggttgg
    36841 aaactttcta atggtacatt ttcggtaaag taatagttat tggcaaccag accttttact
    36901 aaaatctcac cattttgatc ggtggtatat ttaccaattg cttgaccttt tccgttatat
    36961 agcgtaaacg tcacaccggc aagtggtgtt ttcttcttgt tccattcttc atacttgaac
    37021 aattttacac ttttccgtgc ttgacggttc gcaaaatgga tcactttgat cggttctgta
    37081 tcattggtaa tcgagaacac taatgggttt tgattcaaaa cgtaatttac gggtgctttg
    37141 atttcttcca aacgatagcg ctcttttcca taagtaagtg taccgttagt taggaaaaag
    37201 cctttttcat tggttttaaa gatatccgtt gtttctgtat catttggaat ctccattgtg
    37261 acataacgat tggctaaagt atcaaaaatc ttgaattctg tattggcaag tggaatcact
    37321 tttcctgttt cttgatccac tttcaccact ttaagacgtt gttcaattac tttatcttct
    37381 aaaacataat ggaaagtttg cccattttca gaaattgtga cttcaagtgg ttcaaatagt
    37441 ttataccctt cttttccttt ggtttcagaa agaatgtagg tatcaaagac aacagtattt
    37501 ttaccaaaag tagcgtaacc atcattgtct gtcacaacgg ttttcaccac tttgccagtt
    37561 gtttttgacg tcaaagagat ttcaatgcca gctaattttg gtttgttatc tggattggtt
    37621 gaatcgacta aatctttatt agcaattttc actaaatcaa tggttccttt gatcacttga
    37681 tcttttgcgg tcgcattgac agtttttcct ggttcaacaa caatttcaat tgtttcatca
    37741 gaaagtgcat agcctttcgg cgctttgatt tcttttaaaa catatttgcc aggatcaaga
    37801 tctttaattt ctgcctgtac tttgccgttc atatttttca aggtaatttc tttgatcttt
    37861 ttcccatctg cttgatacaa gccatacacc gcattttcta aagaagctgc gccttgtgct
    37921 ttcacaccgg tttctgcatc ttctttaaag acacgaatgt ttccctgttt caaaatagtc
    37981 aaattgacaa cagagtcacc aggttcaaaa ggattcaata taccaattgt ttgggcacct
    38041 ggacgacgat acgctaatgg cgtacccaat acttcaatct gattgaaatg aatttttgcc
    38101 ttttctggtg cttcttttgt gactgtgatc catgcttcat tcccatgaat agatacattg
    38161 atcccttttg gcttttgaat gccttttaca cgttgtagaa agtcattgcc actttttact
    38221 tttaacgttt cgccaatttt tatcgtatgt gtttgattat gaaaagtagc tcttacatca
    38281 aaattattaa gcagacgttg aatttctgct tttcgacgat cataatcaac acggatattt
    38341 ttgattggga tttttgtgcc caaagcttcc caaatcataa attgtgccgc aatgtattgt
    38401 tcatcggatt tgtctttatt tgtgacatat cctaaataag agatcaagct tgtttttttc
    38461 cgtacatttg aatttttcaa atagttttcc aaagcagtag ctgtataaac ttgaccttct
    38521 gcggctgaga caccaggctc aatacaaaac gccacttgtc cattaatctc aaaacgaacc
    38581 atataattta aagtgaagtt tggattgttc ggactagaag taacaccaat attttcgccc
    38641 caatcaattt tccgaccacc taaaacagct gtattggttg cacggcgaac acgaaccgaa
    38701 cgattggttg gtactgttac taacagtgta ggtgtacctg tttttggaat gtcctgctct
    38761 tttttctttt gatcttcaat actagccgta gattctttgt ttagtttcgt tggttgattt
    38821 tgactagctg cggttgaaga gattgttttt tcaacgtttt cctcattttt tccttctttg
    38881 tcagcagtag ccgctggttg ttccactgtt tcttctattc gttgcttttc ttccgcttgt
    38941 ttctcagaag actctggctt cacagaaggc gttgcttcgg cagctttttc tccttctgga
    39001 gtggacgttt ctgaagcagg ggttgtaatt gaggcagttt cttcaactgg ttgtgaagta
    39061 acaggactat tccctgggtg ttgtgtttcc ccaatcgtct gatcgagagt cgttttggaa
    39121 ttaaccgttg gcgcttctgt cacaggggcc tgttcaacag tggcttcacc agctgggacc
    39181 ccggcttctg ctggttggac ttctgtcact tcagaagcga cttgggcaat ggcttccacc
    39241 gtaggttgtg tagccgtcgt ttcttctgca tgtgcttgag cagttcccac caagaaacag
    39301 aattgagata aggccaccaa tgcgagtgct ttcaaccaat tcattttcgt ttttgcatac
    39361 acaagaattc ctccttttcc tgagaatttt atataataaa acaaaacacc gttaccaaaa
    39421 gtgataacga cgtgaactgt ctcttctatt tttatctggc gctcttatct gaacacattt
    39481 catcaatgat tttaccctcc cactataatt acagaacaaa aaaagaacct gcttcgtgga
    39541 aatcaactgt ccatttccca attggaatac cagctttatt ggcaacttca ccatcaccaa
    39601 atatcatgcc ataccaatta ctaccttcat ccttaatttc tttccaacca tatgacatag
    39661 cttcatctaa cgaatcaaaa atcatgccac tgttgccaat tgttgcagga tctggcttaa
    39721 gatcttctgg aatagaaata tcaatcacac cataatgatc cgattcccca gtattattgt
    39781 cattactagc tactggtttg gttgttctac tgacttattt tgatacaaca agtacgctta
    39841 ttcttctttt acttctccgt tttcaatttc ccattcaaac cactccgcaa agtcttgctt
    39901 aaaaccatct actcgatacc tattttgtaa ataggcatct tctgacgtcg taggatctaa
    39961 ataggtaggt ttattctctg gacgagcata gacacctacc catgtttcgt aatctccttc
    40021 aaaataacta tctaccaaat agcctttttt tctaagaatc tcccgaactt gatttttaat
    40081 tattgatact tgttcaaaac catcactcat tctatcacct caaataactc tagattctca
    40141 taaatattcc cgacaatttc aatcctatca atgatctcta acaaatcgct acttatgctt
    40201 ccccattcgt ataagaattt cccttccgca aaataaattt tccataaact tcttcatgat
    40261 cgtcccaacc aatatcactc tcgacaaatt ccacgttgtt cttatctttt agctcagtaa
    40321 atgccataag ttcaacatgt tttccaacct cgaaacaatc acaccaccca tcaaccgtta
    40381 cacgtgtgcc ttcaatacct aagaaacttt gtcctcgtgt attaaacact aaaactttcc
    40441 gcattttttg ctcattaatt aatcacgcgc gaaatctagg aatcacaact tgttcgcttc
    40501 ttctttataa aataaaaaaa ctccaataat cggaaattac tatcttttcc tcattccttt
    40561 tttaaatctt catacttctt cttatctttg tcctaaccta ataacacaaa ttttgaagaa
    40621 aaactcagta aaacctgatt ctttttttat cttcacaaca accaactttt tcttcagatc
    40681 cttttactag aacttgtata caaaaattgt tgaatgctga tacaatttgc ggttacttga
    40741 aaaaacgata gatgtaaaaa gataaataga atcatttttt tattctatat cagtctatga
    40801 ttcattgctt atcaatcacc caacccattc gatgccgttt ttttaagaga aatttaaaaa
    40861 agaccgtacg aatctcgcat tgtccgatta cttttctaga aaagatcccc aattctgtat
    40921 aaataaccct atcttcttgt tggtttcatt ttctcatata agaattcagt caatctaccc
    40981 actatgacca ttactacgtc caacacaacc gacatattaa ccacgtaagt attccctcac
    41041 agatctccga atttccatgg tatggattcc catcctgacg ctgcagagga caacatattt
    41101 catgtggctc tgtacccttt tgatttggaa agactacaaa tcaatactca tctataactt
    41161 atcaagcgaa ctttcgctag gcttctagtg attactaaat tgttggataa catacctagc
    41221 ccattttatc tagctggtat tcataacagt tatttcttgt attacttctt ccgcttgtgt
    41281 tgccattgag cttgtcaaaa agttacttag aaaaaagctg ccagtaaagc aactttcaac
    41341 aaaccctttt tgtttcttat catatcaaga aacctccttt tataaatttt tctataataa
    41401 aaaaacgtcg ataacttaat aagtatcgac gtaaactatt tttatatccc gtaaatcaaa
    41461 aattctaaag aaagatttcc tatataagca tattggataa ttcgattagt attgggtata
    41521 tctctaccat tctcatacct atctatggac cattttgaaa ttgaaggaga aaaaagcttt
    41581 ccaaactcct ccctttctag ataataatct ttcctaattt tcctcatcct taatcccata
    41641 ctaaaagaat ttatcttgtt aaaatcgcta actctttcat cttttggaag tatattctta
    41701 taatcttctc cgtacataag gtaaggaaca gtgaccttac caagataggc aatattcatt
    41761 agtttttcaa tatctggaat attaatacct ttttcccatc tacttataac atttttgcct
    41821 gtatagatgg taaagttttt accaaatttt tcaagcgtct cttcccggtt ctttcggact
    41881 tctcgtattc tttttcccat aacaatttta tcgtcttttg ataaactaaa tatctcacta
    41941 tcacgattac tctccttcga aatttctttt tcattactta atagaaaaat atcgattttt
    42001 ttttgcattt cttttgacgg atttctcttt ctatttaaca cataactgag taatacttca
    42061 ctaattccta tattatcagc taactctttg ttaagtaact tattcatatc tctgtatgca
    42121 attagttgac cgatgagaat ctcaatctta tcttcctcat cttttattag agtttctata
    42181 ttcaaaatct tgcttagagt attatctacg tctttaggga tttttcttga ccctttttca
    42241 tatttaacta aagtactttg tgaaatacct gctaaatcag ctaacttttt ttgagatagt
    42301 tttttctctt ttcttagaga tttaagaacc cttccacttg aattatcaac catgaaaaaa
    42361 gcaccttcta tgagatgctt tcatcatata ctgacagcta aaaatcttca agaaaaaata
    42421 ttccaatttt gttaatttta gtatcgccgt gataaccaaa tgacagttta aaatctttta
    42481 tacagataat cctcagtgtt gcatctactc aaaaaggttg atttaatagg tttttcgatt
    42541 gattataagt tatttcacac tatcttgctc atccattttc agaacggcca tgaaggcttc
    42601 ttgcggaact tcgacggagc cgatttgttt catccgcttc ttcccttctt tttgtttctc
    42661 taagagttta cgtttacgag aaacatctcc accataacat ttagccaaga cgtttttacg
    42721 caaggctttg atgtctgaac gggcaacgat tttttgtcca atagctgctt ggattggcac
    42781 ctcaaattgt tggcgtggga ttagtttttt cagtttttca acgattgctt ttccacgttc
    42841 ataggcaaag tctcggtgaa cgataaagct taatgcatcg actttttctc cattcagcaa
    42901 gatgtccatc ttcactaact tgcttttttg ataaccagac atttcataat ccaatgaggc
    42961 atagcctttc gtgcttgatt tcaatttgtc gaaaaagtca aagacaattt cagaaagcgg
    43021 aatattatag acgacattta ctcggtaatc atctaaataa tccatcgtaa tgaattctcc
    43081 ccgttttcgt tgagaaagtt ccattactgc accgacaaaa tcatttggga ccatgatctg
    43141 tgctttgacg aatggttctt ctacatcctg aatcgttaca ggttcaggaa aatctgccgg
    43201 gttatctact gtagcagtcg taccatccgt tttattaaca tggtaaataa cggatggtgc
    43261 agtcgtgatc aattctagat tgaattcccg ttccaagcgt tcttggacga catccatatg
    43321 aagaagtccg aggaatccac agcggaaccc aaaacctaat gcttgagagg tttctggttc
    43381 gaattgtaaa gcagcatcat tcaattgcag tttttctaaa gcttcccgca aatcgttgta
    43441 acgagaagta tcaattggat aaagaccaca ataaaccatc ggattcattt ttcggtaacc
    43501 tggtaaagct tcagcggcag gattgtctgc taacgttact gtatccccta ctcgtgtatc
    43561 ttggacagtt ttgatacttg ctgtgatata accgacatca ccgaccatca aaaagtctct
    43621 agcaactgct tttggcgaga agaccccgac ctctgtaaca tcaaatgttt tgccattact
    43681 catcagtttg attttgtctc cgggtttgac cataccgtcc gtgatccgga catttagaac
    43741 aacaccgcgg taactatcat aaatagagtc aaagatcaaa gcttttagcg gtgcatctaa
    43801 gtctccactt ggtgcaggaa catattccac gatctgctcg agaatatctt caatcccaat
    43861 ccctgatttg gcactggcta atacagcttc actagcatcg attccgatta cgtcttcgat
    43921 ttcttgacgg acacgttcgg gatctgctgc gggtaggtcg attttattga tgactggcag
    43981 gatctccaaa tcattgtcta acgctaaata aacattggcc aatgtttgtg cttcgattcc
    44041 ttgtgctgca tcgaccacta aaacggcacc ctcacaggca gcaaggcttc gagagacttc
    44101 ataggtgaag tcgacgtgcc ctggggtgtc aatcaagtga aagatatatg tttctccatt
    44161 tttcgctgtg taattgagtt ctacagcatt taatttaatc gtgattccac gttcacgttc
    44221 caaatccatc gagtctaaca gctgatcttg catttcgcga gacgtcacag tgtgcgtcat
    44281 ttctaaaata cgatcggcca atgtagattt cccatggtcg atatgagcga tgatcgaaaa
    44341 attacgaatc tgctcttggc gttctttcat tttctttata tccatagcgt ctcctctttt
    44401 catataatca gcactttcca ttataccaac gaaaagcagt aatttaaaga gtttttaatt
    44461 agtcagctat agaagttttt tttgtagaat tttgctatac tgttatcaag ctaataaatg
    44521 gagatgaaaa aatggatcaa aaagatttta gagaaaatct tgaattaaaa ccggtcactc
    44581 aagaacatat cgatcaattc aatgaattgc tttcctatgt gttccaagtg actgaagcag
    44641 acatcgagga aagcgggttt gagaataaac gagcttttat ccgttccaaa aaaccgattt
    44701 tggaagtatc gaaagtgttc ggatggttcc acgaaaataa actgatctct caaatcgcta
    44761 tctatccttg tgaagtcaat attcacggtg cacgttataa aatgggtggt gtgactggag
    44821 ttggaactta tccagaatat gctaaccatg gattgatgca agatctaatt atcgttgcat
    44881 tggataatat gcgcaagaat aagcaatgga tctcttattt gtatccttac agtatcccct
    44941 actatcggcg taaaggatgg gaaatcatgt ctgataaact ttcctttaaa atcagagata
    45001 cacagctacc taaacaaatc ccagtaagtg gtatggttga gcgattacca gttgatcatc
    45061 cagacgtatt ttccgtttat gacaaatttg cccaacaaaa ccatggtgct ttattccgca
    45121 gtgattttca ttgggaagag tattggcgtt tcgaaaatga agatgagcgc acagccgctg
    45181 tctactacga tagcaaccat gaaccaagag gtgttctgtt ctactgggta gctgaagaaa
    45241 tatttcacgt aaaagaaatg ttctatcttg atcaagaagc tcgaaatggc ttatggaact
    45301 ttatttccgc acatttttcc atgatctact gggtacatgg agatatttat aaaaatgagc
    45361 ctttagcatt tttgattgaa gatagtcaga tcaaagagca gatcgaacca tattttatgg
    45421 ctcggatcgt tgatgtaaaa gaattccttc aacggtttcc gtttgttgga acagctgatg
    45481 cttttcattt catcattgaa gatcctgtcg ctccttggaa taatggtgtc ttcgctttaa
    45541 catgggatga acagggacaa gtccgtgtct taaatgaacc tataggaaaa tccgttcgac
    45601 tggatatcca aacattgact tgcttgatga tgaattatcg ccgtgcttct tatttggcaa
    45661 gaatcgaacg gttagaaaca gatgaagaaa cactgaagtc actagagcgt atcattccaa
    45721 acatggaagc ttactttagc gattattttt gataaaaagg atgatgttta gatgaaaatt
    45781 tattttgccg caccaatgtt tgctaaaagt gatttgttat ataaccaaca gttagttaaa
    45841 gaaatcagag agctctcttc tgagctttcg atctatcttc ctcaagaaaa tgaagcaatc
    45901 aatgacaaaa ctgcttatgc agacagtcga atgattgctc ttgctgacac agaaaaagtg
    45961 ttggctagtg atttaatgat tgctttacta gatgggctga cgatcgatgc cggggtagca
    46021 tcggaaatcg gtgtggctta tgcgaaaggc atcccagtga tcggcttata tactgatact
    46081 cgacagcaag gcggaaccca cccgaaaaaa atcgctgcac tacaagaaac agctgaaaat
    46141 caatttcact acctgaactt atatacaata ggtttgatca aattgaacgg aaaagtggtt
    46201 tcttcagaaa ttgagttgct ttcagaagta aaaagatttt tagatggagg gactttcagt
    46261 gattaaagaa atcaaaaagg tgcaaatagc tttacttgct tttggtgtat tcgttgtctg
    46321 ctataatttt tatgaattta tcacacaaaa atattcgact tctcaaggaa tcacatttat
    46381 cgtggaatct ttattaggga ttgcattgat tttcatgcca caagtcattt tgaaagtttt
    46441 caaacttaaa ataccagcag caatcgtttt gttttactgg tttttcttgt tcatctctgt
    46501 ctttttaggc acagggatgc atttgatcag tatcatctct ttttgggaca aaatcttaca
    46561 tgcggtgagt ccaatggtcc tgacagctct tggctatgga ttgattggtt acttgatgaa
    46621 agatgctgag atatcaaaaa ccagtccttg gttgttcctc ttattcggct ttgcgtttgc
    46681 tggactttgc ggcgtgtttt gggagttctg ggaattctta tgcgaccagt tcttaggcat
    46741 gaatcttcaa cgttttgctg cttctgatgg cacactgttt gtcggacgag cagcattgat
    46801 ggatacgatg ggcgacttgc tgacaaatac gataggtgct gccttaatgg gattgtttgc
    46861 atggtctcaa agtaaaaaag atgagcgtta ctttgaaagt tataaattag aaaaagtgaa
    46921 aaatacctaa taaaagaggt tgtgacagaa gcgggcagct tcaagaaatt tcggcttatt
    46981 tttcgaagaa actacttctg gaacactgtt tatttgaaaa aaggaggtct gacactagtt
    47041 gtgtcagacc ccttttttct tttatagtct caatggaaga ttagacgatt tcttctagct
    47101 cttctgtttt gaaatgaagt tgtccatcaa gtaaagtaat cgttactttt gatttaggca
    47161 taacatgtcc tgcaacgatt tctttagcta gtggtgtttc tacttcctta gtgataaatc
    47221 gtttcaatgg tcttgcacca tatgctggtt cataagcatt ttcagcaatc cacgttttgg
    47281 cttcatcact gattgtcagc aggatttctt gatgttccag acgttgtgcc aattgcgcca
    47341 ccattttgtc aacgattcct ttcacgttgt ctaggctcaa tggtgtaaat aaaatcgtgt
    47401 cgtcgattcg gttcaagaat tctggtttga agtttccacg taatagcgtg ttgacttgtt
    47461 cagccactgc ttctggaatc gttccatcag cagtcacgcc ttccagcagt aactgtgaac
    47521 cgatattgct ggtcatgatc agaaccgtat ttttgaaatc tactactcgc ccttttgaat
    47581 cagtcaagcg tccgtcatct aggacttgta acaagatatt gaagacatcg ggatgcgctt
    47641 tttcgatttc atccaacaag acgattgtat aaggatttcg tctgacagct tccgttaatt
    47701 gaccaccttc ttcgtaacct acatagcctg gaggagctcc gactagacga gacacagcat
    47761 gtttttccat atattcactc atatcgatcc gtaccatatg atcttctgag tcaaacaagt
    47821 tctcagctaa cgctttcgct aattcggttt ttccgacacc agttggtcct aggaaaagga
    47881 aagaacctag aggacgattt gggtcttgca atccagcccg tgaacgaatt accgcgtcac
    47941 tgaccgcatc aactgcttca tcttgaccaa tcactcgttt atgaagtgtt tcattcaatt
    48001 taattagttt ttctcgttca ccttctacaa gtttcgttac ggggataccc gttaatctgc
    48061 caacgacttg agcaatctca ttttcggtaa cggactcttg aaccatctta atctcgctgt
    48121 cttttgcttt agcttctaat tccttcaatt ctttttctaa ttgaggtatc gtaccatgac
    48181 gcaatacagc agcgcgttct aaatcatagt tattttctgc atcttctaat tcgtgttttg
    48241 ctttatcgat ttcagcacgt tttgctgaaa cagaattgac ttcttctttt tctgtttccc
    48301 actgcatctt catcgcattt gcttcttcac gaagttcagc taattcttct tgcaaatttt
    48361 tcaagcgttt tttacttgca tcatctgatt cttttttcag tgcagcttct tcgatttcca
    48421 actgcatcaa acgtctagta acttgatcta attccgttgg catagagttc atttctaccc
    48481 gaatcgttgc actggcttca tcgatcaaat cgattgcttt gtccggtaag aaccgatcag
    48541 taatataacg gtcagataaa gtagctgctg ctactaatgc gttgtcatgg atgttaacac
    48601 catggtggat ctcaaaacgt tcttttaatc cacgcagaat actgatcgta tcttccactg
    48661 ttggttcttt gactaatacc ttttgaaagc gacgttccaa cgctttgtct ttttccatat
    48721 attgacggta ctcatctaaa gttgtggcac cgatcaaatg taattcaccg cgagcaagca
    48781 ttggtttcaa cagatttccg gcatccatac ttccttctgt ttttcctgcc cctacgatat
    48841 tgtggatttc atcgatgaac aagaggatac gtccatcact ttttttgact tctttcaaga
    48901 ctgcttttag tctttcttca aattcaccac ggaattttgc tccagcgatc aatgcaccca
    48961 tatctaatga aaaaatcgtt ttatctttta aattttcagg cacatctttg cgtacgatac
    49021 gttgagcaag cccttcaacg attgccgttt tccctacacc gggttctcct atcagaacag
    49081 gattattttt tgtttttcgt gaaagaatac ggatgacatc acggatttct tcatcacgac
    49141 cgatgattgg atccattttt ccgcttttga cttgctgtac taaatcaacg ccgtattttt
    49201 ctaatgcttt gtattgttct tcttggtttt gtgaggtcac tctttctcct cctctcatct
    49261 cttcgatgtt tttacgcaat tctttttcag ataatccgtt tttattcaaa taaacagtta
    49321 acggataatt ttttaatttc atcaacgcta aaataacgac ttccgttgaa agaaactcgt
    49381 cgccgaagct ttcacgtatt tggtctgctt cattcaataa tcgaaagaaa ttctggctga
    49441 ggttttgtcc atattggacg tttccaccag aaacaactgg atactcatcc agtagacgat
    49501 caatttcatg ttcaaaagat tcgacatcca atccggcatc cgtatagaaa tttcgaccaa
    49561 aatgattagg ttgtaaaaag attttccata catgggcaat gtcgatatct tgatgttttc
    49621 gagtgaccgc aatctgttga gcttcagcaa tcgcttcttg aagcgtcgta gtcattttct
    49681 caatattcat acaggtatac cctcctaatt aaaggtaaga tcacttattt ctttgatctt
    49741 tacaaaaact attatatcgc tttggtcaat tttggtcaaa atatacacat ggttttttga
    49801 ctttttttct cgacttatat aaatcttaaa aaaacaaaat tgattgtatg tatataaaaa
    49861 aagagccaaa caaacgtaaa attatcttat ccataacgtt tttctttgat ttgataaaaa
    49921 gggtagatct tataaaagac ctacccttga ttttctttat tctctttttt tacttctatt
    49981 atttcttctt tgatcactct tcgccgttca gcaatcacat acacaaatcc atagagaaat
    50041 ggcaagataa aggaactgaa acgatacagt aaaagcgaag aaactgcgtc aactgttcca
    50101 acaactggtc tgaataataa caaatagaca aattcaaagg aaccaatacc agcaggcgta
    50161 ggaataaccc ctgaaagcac tactgcaaag ctgataaacg aaatggtcag tagaaaatct
    50221 attttaggat ggttttcaat cagaatcaaa taaggaagta cataccaaaa tacaagtttt
    50281 aacatattcc atagataaat ccgcaatagc gcagtcctgt cttggataat ggtttggacc
    50341 gtttccctta aagagtagat ctgctgattg catgtatcca cccatttccg caaacgctca
    50401 cttttaaata acttattcga taagctgaca aaaaatattt gaacattcaa gctgacggac
    50461 atcgccaata aaaaggcaac aatcacgatc gtcaaaagga taccagcgat gataaaccag
    50521 atcattgatg gaccattaga ataaaaaaga gagaattgga tgaccaagcc agctaatgca
    50581 taagtgatca ctgccagttt gtacataatc atatggagtg ctgtcacccc tgctccctgg
    50641 gatagcttca ttcctttttt gttataaaaa taaatctccg agatcagcgt tcctgtacca
    50701 aacgaaacga ttcggtaaaa cgcaatatag ctagaggtca agaacccatc tttcgttgta
    50761 aaattcggcg cgaaaggttc agcaatttct ttgattgagc gcccttcagc gatttggtaa
    50821 actgtcccta atataacagc cgctgccaaa acaacaacac tggtagacag caattcggca
    50881 aagatatctg caaatgattg attgattaaa taataaataa tggcaaaaat cacaatcagc
    50941 aaaagcagat tcagaatgat tttagttttc gttcctttag acgacatctc ctgctcctta
    51001 atggaaaaaa taaatgagaa tcaaatcaac aagtacacct gcagcgaatc ctatagtaaa
    51061 cttctttttc cgagttttat gatggaaaac ttttcgagag atcaatcctc ccaaaccacc
    51121 gcctaacagg ctgacaaata tcaaattatt ctcaggaaca cgccagccgc tagttctagc
    51181 ctgatgttta tcatacccca tcagacaaaa taagtaaaaa ttcacaatga aaaggtaaaa
    51241 ccacaaaaga ttgtgtaaca atacatccat tactcttctt ccaactttct gttaactact
    51301 atttctaagc tttttcttct ttctttggtg aataaactgt taatcctttt gatacaacag
    51361 ataattcaac tggaagatca tctgtcgtgt ctccatccgt tcgagtgccc acagattttt
    51421 cctgcgcttg gattttcatg cgtttggctg tgaaataagt aatgccgggg atcgtataga
    51481 atttgcctct catgattcta ggcaaataaa aaataaatcg gaaaatatct aaggaaggta
    51541 cgatcgttac atgaaatttt ccatcatcta gggtcgctga gtcgtcaaaa tttgtaaaac
    51601 cgcccacgga gttagacatc gtgactgtca acagttggga ttttcctttc caatgctcct
    51661 cgtctgtttc taaatccaaa tgatattttt tcttcttcag caataactta aaaaacttct
    51721 tgataaagat ccacgagccg taacgctgtt tttcttcttg actgatccaa actgctgtat
    51781 ctgctaagat tccgattgtc agtgtagaga taatgacttc atcattgact tgaccatagt
    51841 ctattttccg tacattgcct tccaggatca cgtcagcagc ttcttctttt ttgaggggaa
    51901 tctcaagaac acgtgcaagg ttgttgacag ttccacctgg aagtaatccg acatggtatt
    51961 gagataatgt tttttggaac gcttggacga tatgatgaat cgtgccgtct ccacctataa
    52021 ttactaaagt atcagcttct atggcttctg ctttcttgac taattccgca tcatcaatcg
    52081 atgggccagt ttcagctagt tctacatata attctggctg cttttctttt acataatctt
    52141 gaaaccagcg tgctaatttc tcaccctcat ctttccctga acttttgtta taaaaaacta
    52201 gcagcttttc cattctttac ctcctattta ctcttcaaaa aagagggcgg gacaaccaat
    52261 tccattgtcc tgccctttag ccttagacag atgacattcc atcattggga cgaacgcctt
    52321 gtcataagct gttctttttc gattttaact ctttgtgttc aattctgcaa tttttacaat
    52381 cacgtctgtt gctttttcca ttacttgtaa agaaacaaat tcgaatcgtc cgtgcatatt
    52441 ttctcctccg gcaaatagat ttggcgtcgg aatacccatg taagagattt ttgaaccatc
    52501 tgttcctcca cgaactggtt cgatcactgg agagatacca agctcgatca ttgcttgttt
    52561 cgctaattcc acgatgctca tatctttttc aatgatttct ttcatgttgt aatattgatc
    52621 atacatatct actttgattc gttcttgatc aaatcgctga ttcaactctt cttggatatg
    52681 tgtgatttgt gctttgcgtg cttcgaattt ttcacgatca tgatcgcgaa tgatataact
    52741 catagaagct tcttcaggat tcccatccaa tgccatcaaa tggaagaaac cttcgtatcc
    52801 ttccgttttt tctggaactt catcggctgg aagctgatta tgaaaatcga ttgctaactg
    52861 tagagcattg atcattgtat cttttgccgt ccctggatgt acatttttcc cttggatcgt
    52921 aatatttgct tgagcagcac taaacgtttc atactgcaac tcacctaaag gaccaccatc
    52981 gactgtataa gcaaaatcta catcgaattg ctcaacatcg aatttatccg ctccgacacc
    53041 gatttcttca tcaggaccaa aagccacttt gatggtaccg tgagggatag aaggattatt
    53101 gatcaagatc tccattgcag tcatgatttc cgcaatccct gatttgtcat ctgctcccag
    53161 taatgtactg ccatctgttg tgatcaatgt gtggccttca taatttttca aatttggaaa
    53221 atcttttgta ttcaatgtat agcgttcttc cgcatctagt acgatcgtag actcgccatc
    53281 atagttttca atgatttgtg gattgactcc tactgcatta aaatctgctg tatccatgtg
    53341 ggaaataaat ccaatggaac gcacttcatg atcaacattg cttggtaatg ttcccataac
    53401 gaatccgtta tcttcattat agaaaacatc agctaagcct aactcttcta attctttttt
    53461 caattcttgc gcaaaagcaa cttgtgtctg agtcgatgga gtcgttttgc ttgttgcatc
    53521 ggagcgtgtt tctgttttga catatcgtaa aaaacgtggc aaaagatttt cgtacatagt
    53581 attctctcct tttaattaaa ttgaaatggg tttgtatttg tttcagaaac gaaaaagtta
    53641 atatcccaat tttcttcttg tttccaagat tcaaatttct cgataaatcg ttgcttgcat
    53701 aacgattcaa tataatgacc gggatcaatt gcaatcaacc cagcgctttg catatcatga
    53761 gccgtatgat aatagatatc tcccgtgata tagacatctg ctctttgggc gattgcttgc
    53821 ggataaaatt tttcaccgct tccaccgcaa atcgcaatgc gcttcacaga ggattttgca
    53881 ttttttggct ggactattct cagtccatct agttggaacg cttcttttac ttgttctaca
    53941 aatgcctcta tagaaatttc ttgcggcaat tcacctactc gtcctaaccc aaacatttcg
    54001 actggttcat ctatagcgaa aagatcataa gcaggttcct cataaggatg agctgaccgc
    54061 atggcttgaa tcacttgttt ttcgatagtt tccggcaaaa taacctcaac ttttgcctct
    54121 tgaacttgtt ctgtcttccc tactttccca atcgctggtt gtgcaccagc ttccggagta
    54181 aatcgaccgt gtccaatcga ggtaaaactt gtaccggtat aatcaccttg tgtaccagca
    54241 ccagctgcag ctaatacttc acgcattttc tgtgcatgat ccacaggtac ataaacggcc
    54301 agttttttat aatgaatctc atgagtcttt actaaataac tctccacttc aataccgaga
    54361 agttcacaaa accagtcatt cagtccatcc caaataatat ccatgttcgt gtgtgctgca
    54421 tagacggcaa tatcatgttt caacaaatct gcatacattt tttcttgtgg ctgatcagta
    54481 accagccgtt ttacaggacg aaagattgga ggatgtttag caatcagcaa atcgattttt
    54541 ttcttgattg cttcttcgac cacttctgga cgaacgtcta atgtcatcat tactcgttgg
    54601 attggcttat ccaatgttcc gatatgcagt ccgactgggt ctccttcttc agctagccac
    54661 tgaggacaat agctttcaaa cttttggatg aaagtgcgtc cgctgattgt catggcttta
    54721 aaacctcctc aatcatttgg atttcctgct cgatttgttt ttgacgtgcc tcttgattag
    54781 ctgcttgttt gagctgttca cggatagctt ttctttgttg aagctctctt gtccattttg
    54841 atttgaagat ctcacttttc tcttcaagca gaaatggccc gaacatcagc tccatttcat
    54901 tgtaagtaac tggtttttgt tctttttcgg ctacaatgat ttcatatatt tttttatttt
    54961 cttcaagtat tttttctgat tggattttat actgattttc ttgcagccaa gatcgtaatg
    55021 tacgctctcc gatgtttggc tgaaggatca aacgttcttg tccgcttaag cgttgattca
    55081 acttgccagc ttctaggata tctcggatca gtgaacctcc catacccgca atcgtgacag
    55141 ctgtaatacc atcttgtggc tggatagcat ctagaccatt tgcaaggcgt acggtgatac
    55201 ggtcttctaa tccatctttt ttgacttgct tacgtgctga ttcataagga ccttgaacga
    55261 cttcaccagc aactgcatat tcgatttttc ctcttaatat caatgcaacg ggtaagtaag
    55321 cgtgatctga tccaatgtct gctaaacgag cggattcagg gacaaagtca cccactgcgg
    55381 ctaagcgctg agataaatct aaatggttca tagcttcact ccttctagat aattatagca
    55441 ttttccaaat aaaataagga gactaggaat aaaaaaattc ccatatctcc ttaaaaaata
    55501 taccttttcg ttctataaaa caacattttc ttatttttga aaaaatgtta ttggttattt
    55561 gttcaatgaa acatcaataa tcgaatctcc aggaacttgc ggtgggatag acatcgtcat
    55621 gatcggcatc tcaactaatg taaattggac tttgtcaccg attttcaatt catttatgtc
    55681 cacgcttatt ttttcagcag tagcatttaa gatcactccg tcattgctga atgacgttcc
    55741 catattcgct ggatcttctt tggccatgac atcgacgagt ttcaactgaa gcgtttcttc
    55801 ttctgcttct acttgagtaa tactttcaat cgttccgaca aatatgcttt gtctctccgt
    55861 tttcgtactg cttgttttta ctgtttgacc cgcatcaatc gaatcaacag aacctgtgtt
    55921 gctatctgcg ctaccgcagc ctgctaaaag aaaaaataga ccaactacag atatactaga
    55981 aaaaatagcc ctcataaaaa atcctccgtt taagtttctg cattacttgt tgcggtgatt
    56041 gtctccggtc atttctgtcc atataatgat tcgctgacct gcttttacta ctaggtcaaa
    56101 tgtcagttgg acttgtcaac tgttcaacca ttgcgtcggt tgcgaccagt catttcgatt
    56161 tcttttgtca aataacgtat gcgttccatt atccgtttcg cttttagcgg ctcttcatct
    56221 ccacgttgag tgacggacaa atgctgttcc aattcatcca ttgtaaaatt cgatgagaag
    56281 aaggttggta actgttcctg catccgatat tgaaggataa caccgaatac ttcgtctcgt
    56341 atccaactac tcatcgcatc tgcaccaatg tcatcgatca tcaaaatagg tgaacgtttc
    56401 actgcatcta acttttctgc cacttgatct tttccgattg cctgtttcat ctcaacggca
    56461 aatgtcggaa aatggactag cgtcgtggtg aatccagcaa tcgctaattc tctcgctgtt
    56521 gctcctaata aatatgtttt tccaatacca aaacttccta ctagatacag tcctttatga
    56581 tacccttttg gatcagcagt atatttctct acaaaatcta gggcttctaa gctcgcatat
    56641 cctcgtccat ctgtacgttc aaagttttca aaagaagccg attgaatatc ttttggcata
    56701 tccattgctt ttactcggct tctgatttct tcttgtcttt gccgtgctaa caatgcttcc
    56761 gttggtacat aagtgacatc cacataatga aaattcaacg tcagcttcgg ctcatagccg
    56821 ggagcgatca tcgttggatc gtttttttga tatttacgct tttcttgcac gaattcatac
    56881 aatttagcgt aacttttttc aatatccgct tgtgtcaatt cttcttggtg tgcgcttaga
    56941 aaagcttgaa catccgcatc atttaagact tcagcgatca tttcagcata cttttcttga
    57001 taattgcgtt tgctgatgat cctcttcaat tctttgccta cgtcttccac tagatatcac
    57061 cctccttttt tgccaggtat tctttaaaac ggcggtcaat ctctgctttt ttctcgctgc
    57121 tgatctgttt ttcatctttt ggctggttga cccaatcagg aagcttttcc cgtcgaacat
    57181 ttcgcttgcc agtttgataa tttgtttgct tcttttgttt tgattgtttt gcttgattac
    57241 ttatttgccg aatgtgctgg atcgcttctt ctgctgtggc gattttcttt tgtgcccatt
    57301 catttgccac tgtatttaca taactggcat ttaagctagc attattcttg atcactagta
    57361 cataattcag caaaacattg atcacgctac tggaaagacc tgattgagaa acaagatctt
    57421 gcagtaacca gttttcttgt ttagaaacat atccgccttt ttctgacttg attgcttcca
    57481 gatatttcat cggtggaatg ctctgtgctt cttttatcag ctgaagcgct gcgtttgtca
    57541 aatgttcgtt tgacgagggt tcattactgt tttcagaaac cgcaactgtt tcttttgttt
    57601 gcttcaccgg acgtctctgc attgccaaaa tggctttttg cagttctttt tcagatactt
    57661 tttgttcact aaagtcataa gattgactga tcagttcgcc aagtgtcaat tcatcgaaac
    57721 cgtaaagctg atgatacatg tcgacttgtt tgatgattgg atcatcaaga cttgcaatat
    57781 gtttttttgc cagccaatca ttcaaaaact gccaatcgaa tgtcgaatct gcttcaagta
    57841 atgctactga ttcagattct tcaaaagatt tattcagcga ttcgatgttt tcttgattag
    57901 cagcgtacac tgcttcattg aagcgataaa catctaaaaa tttttttgtg attttttgat
    57961 atccctctgc tgtatgcctt ttaggttcaa agaattgggt aagcttctgg aatcgtcgtt
    58021 caccaacttt ttccagaaga agaaaagcca gaacagagtc tttgaaaaat gctttaggaa
    58081 tgagtggttc taacagctca taaataaaac gaggtcccag atcactatct tctttaaaat
    58141 aaacatccag taagccgatt ccttctagct tttttcttgc atcataaaat tgcgggatac
    58201 cgcagcctag actactaagc agatctgcat gcatcccttc aggacctttg ccagattctt
    58261 gagagatttc tgataacagg gtgaaataga tactcaaggc ttctccgccg attagtggct
    58321 gataaagata cagcaaggcg ttcttgctgt cttctctcag cggagccgct tttcttcctt
    58381 ggtaaatatt ttttggttga agctctttcc aagcattttc caaggaaatg cctccttttt
    58441 gtttcttaat tgttttcttt attattctct ttattatttt cttttgcttt atccacgata
    58501 tcttgcaact cttttaagaa aacagacata tctttgaact ggcgataaac acttgcaaaa
    58561 cgaatataag cgatttcgtc taaatcaact aaatcttcca tcacatattc accaattaga
    58621 ttcgtcgata cttcgttttc tccgagactg cgtacgcggt tttcgacatg gttgacgatt
    58681 tgttccattt gttccatagc tacaggtctt ttttctgctg aacggatgag tcctcttaaa
    58741 attttatcgc gattgaactc ttcgcgttcc ccgtttttct tgattactaa taacggagca
    58801 gcttcaattc gttcaaatgt agtgaatcgg aacgaacaat tctcacattc gcgacggcga
    58861 cggatcgcac gtccatcatc tgcttgacgg ctgtcgatta ctcgtgaatt attatgttga
    58921 catctgggac atctcatttt gtctcacctc ttgcatcgca ttttatataa aggatgtgtc
    58981 tttctttaca actagttgta ttataacacg aaacaaatca caaacgcgac tgtcctaccc
    59041 aaaaaacacg gatataagaa caattttttc tactttcatg cgtaattgtg tcccctgtcc
    59101 ttactaaatt tcaattttcc aatactgatc accttgatta ctgagaaata acttacacaa
    59161 aagctgattt agtcatctag cacaaaaaac ttgaagcaga tgaacacctt ctcatctgct
    59221 tcaagtcaca tctcgatttt ttactatttt ataacttctc ttcgattcct gtatagtgtt
    59281 tcattcgctg ttcctcgatt ttttgctcat cggaaatgtg gtcactttct gggagcggtg
    59341 ttttactacg atcaggtgtc ggattttttc gttcttgagt caaatcttgc cgcttcgctt
    59401 cttcttctgc ctgctggtct tctatttcat cgattcttgc ttggtactgc ttttcttttt
    59461 cttctgctgt ttctgattgc gtacgacctt catcgattag attttcttta ttgagcatct
    59521 cgccgatttt ttcttttgcg ttacctacga ctttatcctt ttgatttttt aatgatccca
    59581 tcgctatccc tcactttcta tatactcagg atagcaaaat tgacacagat actcaaagaa
    59641 agcgattagc aaaaagccaa ttttcgattt gtcccacaag tttttctttt gttccattgt
    59701 tgtcgaacaa aatatccgca cgctgctttt tttcttcgat tggaagttga ctactaattc
    59761 tctgctgcgc ttgttctagc gtcagttgat tacgtttcat caaacgctga agctgagttt
    59821 ctggcgtagt ataaacgaca gctactgcat ccatatagtg gtcataatga ccttcgtaga
    59881 gcaatgggat atctacaatt actaaaggat gattggaact tagagaggcg atttgatctt
    59941 ttatcgcttt tcggataaac ggatctaata gctgatcaag tttttgccgt ttttcctttg
    60001 atggaaaaac aatcatccca agtttccctc gatctagttg cccatcaggc tgcaatacct
    60061 cttggccaaa cactgataca attttcctca gagcaagcgt tccaggctca acagtttctc
    60121 tggcaatcac atcgccatcg atcaaaggaa atccatgaga ctgaaagact ttggctgccg
    60181 tacttttacc ggtagctatt ccacccgtca aacctaaaac aaatcctact ttgcgatttt
    60241 tagcctttga caattcggac aatagtgcgt ccccctttgt gccacttttg ttttcacgat
    60301 cggcgttcca caacgtatac atggtttgcc agtttgctga tagacatgca gtgctacttg
    60361 aaatccgcct gattctccta atgcattcaa ataactgcga atcgtggtac ctccggcttc
    60421 tattgcacga tccaaaacat caatgatcga tagacgtaat tgttctacct ctttggggcg
    60481 cagtgtgttc gccggttgtt ctggatggat cttcgcttcc cataatgctt catctacata
    60541 aatattacct agaccagtca ctagacgttg gtctagcagc aatggcttga ttgctttgtg
    60601 ggactttttc agtccatttg cgaaatctgc taataagaag ctatctggca aaggctcagg
    60661 tcccaatttc atgattcctc ggtaagttgc acttgctcct ttttcgacga ttgtcatacg
    60721 accaaatttt cgtacatcgt tgtagcgaag ttggcttcca tcctcaaaaa agaaaagtac
    60781 atgcgtatgt ttatcgattg gtgtattttc tttcgtaaat tgatattttc cttccattcg
    60841 caagtgtgag atcagttcac aatgatcgag atgaaaaatt aaaaacttcc ctctacgtcc
    60901 aatggattgg atggtttcgc caacaagaga agcctcaaag atgggtgtct ctggttgctc
    60961 gatgatcttg ggccacaaga cctgaacttt ttgaatcgtt tttcctacta ctaaccgttc
    61021 caatccttta cgaacggttt ctacttctgg taattctggc attttttctt ttcaccttca
    61081 ttatattgct ctgtcttaaa caatgtttat tttgcttcgt accacgtttt tccccaactg
    61141 ctgtcagtga tcagtggtac atgaagagaa acagcttgtt ccataacttc cttcaccaat
    61201 ttatctaatg attcaagttc tttttccggt acctcgaaga caagttcatc atgaacttgt
    61261 aacagcatcg tagcttgaag acctgtttct tttaatcgtt tatccaattc gatcatcgcg
    61321 attttcaaaa tatcagcagc acttccttgg attggtgtat tgatagctgt tcgttccgca
    61381 aaagaacgga tattgtaatt tcttgaattg atgtctggca gatatcgacg gcggtgatac
    61441 agcgtttcga cgtagccttg gtcttttgct tcgcgtacga ttctttccat atattctttg
    61501 acacctgggt atttttcaaa gtacgtatcg atgtattgct gtgctgcttt tcggctgatt
    61561 cctagatttt gtgaaagtcc gtaatcagag atgccataca cgataccaaa attcactgct
    61621 tttgcctgcc tacgcatatt tggtgtgaca tcctctgcct tttcgattcc aaatacacgc
    61681 atcgctgtgc tggcatggat atcttgacct tctaggaagg cagctttcaa atgttcatca
    61741 tttgagatat gcgcaagtac gcgtaactcg atttgtgaat agtcagaaga ataaatcagc
    61801 cagtcttttt ctctaggaac aaatgcctga cgtatctttc tcccttcatc taatcgaatc
    61861 gggatgttct gcaaattagg atcaacagag cttaatcgtc ctgtttgggt caatgtctgg
    61921 acataacggg tatgcacttt tccatctgat tggatcactt tcagcagtcc ctcgacatag
    61981 gtagattgaa tttttgcaat ttgacgatag gtgaggatat cctctacgat tggtgcttgt
    62041 tcacgaagct gttccagtac atctacggct gtggaatatc cagtttttgt ttttttgata
    62101 acgggtaatc ccattttttc aaataagatc actcctaatt gctttggtga attcaaattg
    62161 aattcttcgc cggcttcttc gtagattttt tgttcgatct ctcttaagcg agcagagaac
    62221 tcgcccttca tttcttgtaa gcgagtcgca tctactttga tcccgcttat ttccatctct
    62281 gccaaaatga tagacaatgg cagttccatt ttccggaaaa gatcttcttg gtttttatct
    62341 gccagttctt ggctcaattt tggtgtcaac gcattgattg cagctacttt tcgcgctaaa
    62401 tgagcaaaaa agagttcctc ttcttctggt aaaccttttt tcgccccttt gccgtataca
    62461 gcttcatctg attggatatc gttgtatccg taatgagcag ctattccttc gatatctgtg
    62521 cttttttcat tcgtatcgag aaggtatgca cctagcaaga catcaaaatc gattcctttc
    62581 gtttttccag tatagcggtt taaagcaaca taagttcgtt tcgcatcata tacttttttc
    62641 agccgagtcg gatcagtgat ccaagaatgg aacgctcggt tttcgaatac agatagatcg
    62701 ttcgtgacat aaattttctt ttctgtcccc cacgctactc cgacgatttc ctctgtatga
    62761 taattgtcgc ccatcatttc cacgtacaac gccatatccg tagtaaacat ttcctctttg
    62821 aattcatgaa cgacttcaaa caaaatatca tccattttta cttcttcttc tacgatattc
    62881 aatttagaaa ggaactgatt gaaatccatt tctttataaa acggaacgag tttatcgaga
    62941 tttttccctt catacttcaa tgagtcgata gagacatcca caggcgctga agtattgatg
    63001 gtcgccaatt ttttcgataa gaaagcctgc tctttgtcat ttatcagatt ttctttcatt
    63061 ttgctttgct tcatttcatc gatatgttca taaattcctt cgactgagcc atattgtttc
    63121 aatagcttga tagctgtttt ttcaccgatt ttagtcacac cggggatatt gtcagaggca
    63181 tctccggcta gtcccttcat gtcaataatc tgttttggcg tcaacccatc atatttttcc
    63241 gctacatgtt ctggtgtata gctttcgata tcgctgacac cttttacagt gatatccact
    63301 tttacttctt tactagctaa ttgagtcaaa tcccgatcac ctgaaagcac gacgacatca
    63361 aattgatctt tgtctacttt ttctgccaaa gtaccgataa tatcatctgc ttcataattg
    63421 ggcaattcgt aatactgtac ccctagtcct gtcaacaaat cacgtatata tggcatttgt
    63481 tctttgaatt cgccaggtgt tttggatctt ccacctttgt actccgcata catttctgtc
    63541 cgaaaagtcg tttttcctgc atcgaacgca accagaacat gagtcggttg ctctttttgc
    63601 ataacatttt caaacatcgt attgaatgca tagattgcat ttgtatgaag accgtttcta
    63661 tttttgaaac gttcaagaga attgtgaagc gcaaagaatg cgcgaaaagc cacactgttc
    63721 ccatcaacga gtaataattt attttttgtc atcttcttaa ctccttactg taaagttctt
    63781 attcattcta acaaagaatc ctgcggaatg cgaaaagaaa aagcgggacc ataccaaata
    63841 attcggtata gccccaactg atgaattttt ttctttttta gttgttccgt ccaaagattc
    63901 tcagaaacgc caagaacaag ttgataaagt ccaaatacag cttcaatgcc atgaatacag
    63961 caattccact atgtgctgtt ccgtttgtct ggacatagat attacggatg ctttggttat
    64021 cataagctgt aatccctgca aagatgacga ctaacagtag ggagatgaac agctcaacta
    64081 cgctacttct caaaatgaag atgttcaaga ctagtgcaat gatcactccg attaaagctg
    64141 cctgtcctgc tcttccaacc ccgctaagat ctctttttgt tgttactccg acaacagaca
    64201 tccccatgaa catcaaagta gctgtcaaga aagcttgcgt tactgttcca atatcgtagt
    64261 atgcaagagt aaccgctaat gttatgccat tcaaaagaga gtaggcaata aatccaccga
    64321 ttgctaagct cggattcttt tgtgctttta cgcctagaac cattactaaa atcagttcaa
    64381 cgatccacag acccacaaag cctagtggaa aattattgat aaaagttgct aattgcaaag
    64441 gaaataccca aagagccaag taagaagtga ctgcactaag ggcaagtccc atacctaaaa
    64501 atccataaac ttttgcataa aaacgattga tacctgacat tgatgtactt ggattattca
    64561 ttcaattcac cttcactttc gattgctatt tccaattcag gaacttgtgg cggttggacc
    64621 ataacgacag catccaacac acgatcttcg ttcgtattct ccgcttctac agaaatcgtc
    64681 accacatcct tcatcttatc tacttttatg acctcaaact gaaaagtcag tgtttcataa
    64741 tggaaaaccg gttcaataaa attgacagaa aaattgacaa catgtgatcc tggtccagga
    64801 agatgctttg aaattgcact tgtgatgatc cccatcagca tcactgatgg aacgattggc
    64861 tgttgatatt ctgttttttg tgcaaagtca tgttggatat acaaaggatt tgcatcattc
    64921 gtcaatccca aatacagcaa aagctggtta tcttcaatag attctgttaa ggataacgag
    64981 tcgccttcct cgatttcatt tattgttttt cctagttttc tcggcttacc tatgttcaag
    65041 atagaaaccc tccagtttat ttttaatcat acattattgt accaaaagta gcgtaaaagg
    65101 caagttctgc tcccttgatt taacagattc ctatagttta cagaggtcgt gaaaaagctg
    65161 tcctgcatca aataataaga acagccaaga aaaaacagct tctcatgttt ttgatttgat
    65221 tgggcttatt accgcagatg caagcttttg aacaccgttt atcataagtt gcaaaaaagg
    65281 gggcttggca agatttttgc cactccccct ctttctattt ttataaggac actgcagtaa
    65341 ttgtattaca gtacattttt cgtcgtgctg cttaaaagtt tttcatacgc ttgttcaaat
    65401 ttttgaacat ctccagcacc catgaagatt actactgcat catgataatc taacaatgga
    65461 gatacattat tttctttgat gacttctcca ccttttttga ttttcgctcc aaggtcttca
    65521 atcttaacgt ttccttgttc ttcccgagcc gaaccaaaaa tatcgcataa gtaaacttta
    65581 tcagctaaat caagtgcttc tgcaaattca tccatcaatg caatcgtacg cgtaaacgta
    65641 tggggttgga aaactgcaat tatttcttta tctggatatt tttggcgtgc gccatcaatc
    65701 gttgctttga tctctgcagg gtgatgcgca taatcatcga ctacggtcat gtctgctacg
    65761 atcttttcac tgaatcgacg ttttactcct gggaaagtca gcatttcttc tgcaacttct
    65821 ttcagatcca gtttttcgaa ataagctact gcaataacac ctaaagcatt taagatattg
    65881 tgtttaccga atgctggtac agtgaagtgc ccaacaaatt catccccatg atagacatca
    65941 aaagcagaac cagaagttgt gcgttcgatg tttcgtgctt ggatatcatc gttttctgtg
    66001 acaccataat aataaatcgg cacatttgct tttaatttgc gtaaataagc atcgtcacca
    66061 tacgcaaaaa tagctttttt cacttgtcca gccattgttt ggaaagctgt aaatacatcg
    66121 tcgatacttg tataataatc cggatgatca aaatcgatat tggtcatgat tgcatagtct
    66181 ggtgaatagg caaggaaatg acggcgatat tcacaggcct caaatgaaaa gaattccgct
    66241 tgcggatcac catgtcctgt tccatctcca attagataac ttgttggacg gacaccactc
    66301 aatacatgag agagcagtcc agtcgtactt gtttttccgt gagagcctgt tacagcgata
    66361 ctcgtataat tttggataaa atgaccaata aagtcgtgat agcgaatcac ttccaaacct
    66421 aattcttttg ctcgctggat ttcttcatgt gaatcaggaa atgcatttcc tgcaatgatc
    66481 gtcatccctg gttttacatt atctgcgtta aatggcagaa tcgtgatatt tgctttttct
    66541 aaatctcttt gtgtaaagaa atatttttca atgtctgatc cttggacatt tagaccttgt
    66601 tcatgtaaaa caagagccaa ggagctcatt cctgaacctt tgataccaac aaaatgatac
    66661 aatttatttt gattttccat ttgaatcctc ttctcttatc tagcgtccat tcttttagct
    66721 attacattca acacgctcct cattatctta taaacgattg aaaatttcaa ccaaatttat
    66781 ttggaaagga ggattcgctt gctaaaatgg tcaagtacga gaaaaatccg tttttattga
    66841 ctctttaatt ctggtgtaag aagaccaaac ttcctctgat atatcaatgt gaggaataaa
    66901 atcttttcct ttcggaccat agccgttctc atcgtcatgg agacgttcca tttctcctaa
    66961 tactagcgca tggaaatatt ccttaggcca ttgatgattc agttcttttg ctgtaaagat
    67021 gatctcttca gaaaagtgaa ggatttccgg cacaaatggc acagcattcg cgaaaatagt
    67081 ttgttcattt tgccatactt tctcaaaagt tgctcgagtc ctgcgttgca gtgtcggatc
    67141 attcatcaat aagatttttt ctggtacagc tcctaaggaa tgaagaatct ccagtgaaaa
    67201 agtggcgttc tctccagaat ttgtagactt cgattctatc agaaaagcct tatcgggcaa
    67261 atcatagact tcttttagat actgacgaca gatttcactt tcactcatgc catcttcaaa
    67321 atgaaatcct tgcttttcaa aattctcata aaggattcta gtcgcatgcc ccacccctcc
    67381 gaccaaaaac aattgatcta cttggccatt taaatacatt tgtgctgctt tatcagctaa
    67441 gataggaaga cagtttccag ctaaaataag tgtaggtgcc gtcagttcct caaaatttcc
    67501 ctcttcaggt gcggctaaaa aatttaatag ctgattccag tcttttagat tcctctgctc
    67561 acttttttcc aaaggccttc tatcctttca tctgattttt tgtgcttcat taaagtcttc
    67621 tctttttgtc tcaatccatt tgatttctcc atgacatctt ccacaacgat atttgcgtac
    67681 atcgattctt ctcttgcggc agatcgtggc agaacaatct tggcatcgat aatactccat
    67741 ctttatctgt ttcttcgtca aggctggtgc atagcgcaac cctcctgttt ttttcaaaag
    67801 atacttgaaa tccatatctt tatgctgata ccctcttcca gctagatgaa gatgataatg
    67861 gcaaagttca tgtttgatga ttcctgcaat cgtctcttcg tctgactctt caaatagctt
    67921 cgcattaaaa tctaaatgat gatcgtttaa atgatagcgc ccgccagttg tacgtaagcg
    67981 tggattgaac attgcttggt gcttgaaagg aagctggaag ctttttaatg atatctcttc
    68041 tactaactgc tgcagttctt cttgtgtcaa tttttgttac tcctcattgt tactcttcat
    68101 aaggggaaag catcgtcaaa ctgattctgc cttttttcgt atcgacttgt tctatccaaa
    68161 ctgttacgat atctcctact gacacgacat ctgtaggatg cttgacgaat tttttgctga
    68221 gtttcgatat atggacaagt ccgtcttgct tcacaccgat atcaacaaat gcgccgaagt
    68281 caatgacatt acggaccgtt ccagtcaatt ccatccctgg tttcaagtct tccatactca
    68341 atacatctgt acgtaataag ggcgctggca tctcatcacg catatctcgt ccaggttgtg
    68401 tcagcccagc taaaatatcg gctaacgttt cttctccgac tgataggctt tcagccagtt
    68461 tctctacgga taatcgtgtc aatttttcta ctgcttcttc tgtaccaagc tctttttctg
    68521 aaagttggac tgaagttaat atttcttttg caatagaata actttcggga tggatacctg
    68581 tgttgtccaa aatgtttttc ccaccaggga ctcgcaagaa tccgattgct tgttcatatg
    68641 cttttggtcc taagcgtggc acttttttca attgagttcg tgcggtgaat tctccgtttt
    68701 cttcacgata aatgacaatg ttttgggcag ttgttttatt caatcctgat atatgctgca
    68761 agagctgcgg gcttgctgta ttcacatcca cacctacttg gttaaccgct gtttccacaa
    68821 caaaatccaa ttgttcagcc aaacgttttt gagaaacgtc atgttggtac tggcctactc
    68881 cgacagcttt aggatcgatt ttgactaatt cagctaaagg atcttgcagg cgacgggcaa
    68941 tagaaacagc acttctttct tcaacttgta gatgcggaaa ttcttttcgt gcaatttcgc
    69001 tagcggagta aacagaagcg cctgcttcgt tgacgatagc gtaataggtt ttatggtcgg
    69061 cggatttcaa ctgctcagcc acaaaaagtt cagattcccg actggctgta ccatttccga
    69121 tagctaccat atctacttga tatttattaa ttaattggat aaaagctggt ccagcagctt
    69181 ctctttttgc ttgcgctgca ggtttatgag gataaataac ttcgattgct aaaactttcc
    69241 ctgtcgcatc tacgactgct agtttacatc cagtacgata agccggatca aatcccagga
    69301 caactttacc ttttagtggc ggttgcaaca aaagattacg gaggttttcg ccgaaaatag
    69361 cgattgcttg ctcatctgcc ttttcagtca attcattgcg cagttctcgc tcgattgctg
    69421 gctgaataaa gcgtttataa ctatcctgat aggcttctct gacgaatgaa gaagaaggag
    69481 aggcaggatt tttgactatt tggcgatcca agtaagctaa aattgctgct tcatctactt
    69541 gaaagaatac tttcagaata tcttcttttt ctccacgatt agtagctaat attcgatgag
    69601 aaaccatttt atggacgggt tctgcaaagt cataatacat ttcatatacg cctttttcat
    69661 ctgcttgctc atccttgaca ttgctgacat acataccttt gttatacgta taagaccgaa
    69721 tccaagtccg aaattttgca ttatcgctga cttgttcagc aataatctca tgagcaccgt
    69781 gcaacgcttc ttcggcagaa gagacttctt tttctttgtc aatatatttt tctgcttcag
    69841 attgcacctc tccatctgta agctgcatca gccacttcgc gagtggttca agtccttttt
    69901 ctttagcaat cgttgctttt gtccgtcgtt tttgtttgta tggacgatac aaatcttcca
    69961 cttgttgcat tttcacggct tgggtgattt ctgcttctaa ctcgggagtc agtttccctt
    70021 gttcatcgat tagccgaatc acttcagttt tacgtttttc taagttttca agataggcat
    70081 accgctcttc gatttcacga atctggactt catcaagact tccagtcatt tcttttcggt
    70141 aacgcgcgat aaaaggaaca gtgtttcctt catttaacaa attaagtaca gtagtcaact
    70201 gcttaggacg atagtctgaa agttcttttt gtacaagctg aatgatcgtc tggttcaaat
    70261 tttccgtcat taaaatgcct cttttctgct aaaaattgct tctttattct atcatacttt
    70321 ttatcctggg ttaaactact gaaagaaaca atattctcta taaaaataaa aagagccgca
    70381 acaaagtcac agctccttca ttctttccat tagtcagatt ccatgccaag gtccttcgtt
    70441 gttctgatat tcaatatctt gaagaatacc ttccttgtca aaaacaaccc catgcaatga
    70501 ccctccgaat acagccccac cgtccattcc gattttatga tcctgaatcc agaggtctgt
    70561 tgtctgcata tctccatgga gcattggtgt aatcgtatgt ccaaatacaa ttgtcttacc
    70621 tgtattgttt ttcccttcat gaaatggttc ccttatccaa ataaagtctc ttagacttgt
    70681 cttacgccag tctttctttg tcaaatccac accggcatgg acaaaaagat aattttccca
    70741 ttcataatac aaggggcgct ggactaaaaa tttaatcagt tctgaatatc tcgattggat
    70801 catcatcgag atttcagttg gggagtattc ctccgatgcc cctgggtgaa tcaggctttc
    70861 aaacgtttct tttccaccat ttctcatata aggcgcatac cagtcctccg gtgattgcag
    70921 aaattgcaaa aaatattctt catggtttcc ccggaggtaa atggctcctg tttcttcgac
    70981 taattgcttt cctaataaaa aacattcttt tgtacgagga cctcgatcat tgagatcccc
    71041 taataaaaca agctgatgga tctttggatc ataatagtga ataagttttt caaaaagctc
    71101 atgtttgcca tggacatccc caatagcata aatcaatgat ttcatgtgga tcaccatcct
    71161 caacgctagt atagcgcata ttggaaatgg tcgacaatca aaactattgt tttctattta
    71221 attaaagctg taaaccgcag ttctgcttct tctggagaga ttccatggtc ttgaacatag
    71281 cgattgcgcg gatgtttcgc acactctatg ctacatgctc ctaaatgttt ttcttcattt
    71341 tcaatggaag caagaatctg acgattgcac tcaggattgc tacaattgat atatcgttca
    71401 catggtgttc cgtcaaacca gtcgcgaccg acgatttgtt tatctacttg gttgatatcg
    71461 acagcgatcc gttcatcaaa cacatacatc ttgccgtccc ataattctcc ttggacttca
    71521 ggatccttac cataagtagc aataccgcca tgcagctgtc cgacatcttt gaatccttca
    71581 cggacaagcc aaccagaaaa cttctcgcaa cgaatgccac cagtacagta ggtcactacc
    71641 cgtttttcca taaattcttc tttgtgctcg cggatccagt ctggaagctc tcgaaaactg
    71701 cgtatatctg ggcgtacagc ccctcgaaaa tgtcccaagt catattcata atcattccgt
    71761 gcatcaatca ccactgtctg ttcatctaaa atagcttctt taaattcttg cggtgaaaga
    71821 taggcacctg tcacttggtt tggatcaatg tcctcttcta gctttaaact tacaagctct
    71881 ggacggtatc ttacaaacat cttcttaaag gcatgtcctt cgcttggatc gatcttgaac
    71941 atcgtatcag caaatcgagg atcagctttc attgctttca tataggcagt cgtgttttca
    72001 acggttccag acacagtacc atttattcct tcttcagcta ctagaatacg acctttaaga
    72061 tccaaagatt tgcaaaaggc taaatgattt ttggcaaatt cctctggttc ttcgattttt
    72121 gtataattgt aataaagcag tacttgataa tccatgtatt tcttccttcc ttcttttcgt
    72181 tcctaaacag tataaagaag gcgttcgcat ttgacgattt atttgcttgt gtataattac
    72241 gcatggaaag ttttttgttt acataatatt attatttgaa ttaaaaagac ttcgctttcc
    72301 tgtttcgcac agaaaaa
//
LOCUS       DARPZJ010000010        67763 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.010, whole genome shotgun sequence.
ACCESSION   DARPZJ010000010 DARPZJ010000000
VERSION     DARPZJ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.010"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(99..1229)
                     /locus_tag="SLE23_000829"
     CDS             complement(99..1229)
                     /locus_tag="SLE23_000829"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEI8467750.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="SLE23_000830"
     CDS             complement(1878..3080)
                     /locus_tag="SLE23_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8467751.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="SLE23_000831"
     CDS             complement(3140..3343)
                     /locus_tag="SLE23_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEI8467752.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEQLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="SLE23_000832"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="SLE23_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="SLE23_000833"
     CDS             4880..5692
                     /locus_tag="SLE23_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467753.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6913)
                     /locus_tag="SLE23_000834"
     CDS             complement(6716..6913)
                     /locus_tag="SLE23_000834"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEI8467754.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="SLE23_000835"
     CDS             complement(7059..7937)
                     /locus_tag="SLE23_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8467755.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="SLE23_000836"
     CDS             complement(7976..9094)
                     /locus_tag="SLE23_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HEI8467756.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="SLE23_000837"
     CDS             complement(9091..11190)
                     /locus_tag="SLE23_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HEI8467757.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="SLE23_000838"
     CDS             complement(11241..12062)
                     /locus_tag="SLE23_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8467758.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="SLE23_000839"
     CDS             complement(12059..12868)
                     /locus_tag="SLE23_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8467759.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="SLE23_000840"
     CDS             complement(12889..13383)
                     /locus_tag="SLE23_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8467760.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="SLE23_000841"
     CDS             complement(13395..13883)
                     /locus_tag="SLE23_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8467761.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="SLE23_000842"
     CDS             complement(13960..16656)
                     /locus_tag="SLE23_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8467762.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="SLE23_000843"
     CDS             complement(17084..18157)
                     /locus_tag="SLE23_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8467763.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="SLE23_000844"
     CDS             complement(18154..18981)
                     /locus_tag="SLE23_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467764.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="SLE23_000845"
     CDS             complement(18982..19788)
                     /locus_tag="SLE23_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467765.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="SLE23_000846"
     CDS             complement(19800..20885)
                     /locus_tag="SLE23_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467766.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="SLE23_000847"
     CDS             complement(20902..21444)
                     /locus_tag="SLE23_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467767.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="SLE23_000848"
     CDS             21702..22691
                     /locus_tag="SLE23_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEI8467768.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="SLE23_000849"
     CDS             22688..23425
                     /locus_tag="SLE23_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEI8467769.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="SLE23_000850"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="SLE23_000850"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEI8467770.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="SLE23_000851"
     CDS             23989..24621
                     /locus_tag="SLE23_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8467771.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="SLE23_000852"
     CDS             24706..25353
                     /locus_tag="SLE23_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8467772.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="SLE23_000853"
                     /pseudo
     CDS             25358..26341
                     /locus_tag="SLE23_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            complement(26744..28258)
                     /locus_tag="SLE23_000854"
     CDS             complement(26744..28258)
                     /locus_tag="SLE23_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HEI8467773.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="SLE23_000855"
     CDS             28396..29202
                     /locus_tag="SLE23_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467774.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="SLE23_000856"
     CDS             complement(29377..29946)
                     /locus_tag="SLE23_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467775.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="SLE23_000857"
     CDS             complement(30029..32089)
                     /locus_tag="SLE23_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEI8467776.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="SLE23_000858"
     CDS             complement(32366..33844)
                     /locus_tag="SLE23_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467777.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="SLE23_000859"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="SLE23_000859"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEI8467778.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="SLE23_000860"
     CDS             complement(35150..36070)
                     /locus_tag="SLE23_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8467779.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="SLE23_000861"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="SLE23_000861"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEI8467780.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="SLE23_000862"
     CDS             37799..38332
                     /locus_tag="SLE23_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HEI8467781.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38822..39346)
                     /locus_tag="SLE23_000863"
     CDS             complement(38822..39346)
                     /locus_tag="SLE23_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467782.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="SLE23_000864"
     CDS             complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="SLE23_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEI8467783.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39935..40915)
                     /gene="pta"
                     /locus_tag="SLE23_000865"
     CDS             complement(39935..40915)
                     /gene="pta"
                     /locus_tag="SLE23_000865"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEI8467784.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41068..41748)
                     /locus_tag="SLE23_000866"
     CDS             complement(41068..41748)
                     /locus_tag="SLE23_000866"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEI8467785.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41874..42743
                     /locus_tag="SLE23_000867"
     CDS             41874..42743
                     /locus_tag="SLE23_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8467786.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42769..43284
                     /locus_tag="SLE23_000868"
     CDS             42769..43284
                     /locus_tag="SLE23_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467787.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43331..43924)
                     /locus_tag="SLE23_000869"
     CDS             complement(43331..43924)
                     /locus_tag="SLE23_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8467788.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43949..44128)
                     /locus_tag="SLE23_000870"
     CDS             complement(43949..44128)
                     /locus_tag="SLE23_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467789.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44205..44714)
                     /locus_tag="SLE23_000871"
     CDS             complement(44205..44714)
                     /locus_tag="SLE23_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467790.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44810..45190)
                     /locus_tag="SLE23_000872"
     CDS             complement(44810..45190)
                     /locus_tag="SLE23_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8467791.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45520..46269
                     /locus_tag="SLE23_000873"
     CDS             45520..46269
                     /locus_tag="SLE23_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEI8467792.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46453..47730)
                     /locus_tag="SLE23_000874"
     CDS             complement(46453..47730)
                     /locus_tag="SLE23_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467793.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="SLE23_000875"
     CDS             complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="SLE23_000875"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEI8467794.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48652..49596)
                     /locus_tag="SLE23_000876"
     CDS             complement(48652..49596)
                     /locus_tag="SLE23_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEI8467795.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49598..50284)
                     /locus_tag="SLE23_000877"
     CDS             complement(49598..50284)
                     /locus_tag="SLE23_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEI8467796.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50758..51078
                     /locus_tag="SLE23_000878"
     CDS             50758..51078
                     /locus_tag="SLE23_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEI8467797.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51232..52137
                     /locus_tag="SLE23_000879"
     CDS             51232..52137
                     /locus_tag="SLE23_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8467798.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52134..52907
                     /locus_tag="SLE23_000880"
     CDS             52134..52907
                     /locus_tag="SLE23_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8467799.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53088..54512)
                     /locus_tag="SLE23_000881"
     CDS             complement(53088..54512)
                     /locus_tag="SLE23_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467800.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54723..55169
                     /gene="nrdI"
                     /locus_tag="SLE23_000882"
     CDS             54723..55169
                     /gene="nrdI"
                     /locus_tag="SLE23_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEI8467801.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55234..57216)
                     /locus_tag="SLE23_000883"
     CDS             complement(55234..57216)
                     /locus_tag="SLE23_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8467802.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="SLE23_000884"
     CDS             complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="SLE23_000884"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEI8467803.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58129..59190)
                     /locus_tag="SLE23_000885"
     CDS             complement(58129..59190)
                     /locus_tag="SLE23_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEI8467804.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59401..59967)
                     /locus_tag="SLE23_000886"
     CDS             complement(59401..59967)
                     /locus_tag="SLE23_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8467805.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="SLE23_000887"
     CDS             complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="SLE23_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEI8467806.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61755..62876)
                     /locus_tag="SLE23_000888"
     CDS             complement(61755..62876)
                     /locus_tag="SLE23_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEI8467807.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63002..63943
                     /locus_tag="SLE23_000889"
     CDS             63002..63943
                     /locus_tag="SLE23_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEI8467808.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64093..64989)
                     /locus_tag="SLE23_000890"
     CDS             complement(64093..64989)
                     /locus_tag="SLE23_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEI8467809.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65258..66598
                     /locus_tag="SLE23_000891"
     CDS             65258..66598
                     /locus_tag="SLE23_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8467810.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66816..67259
                     /locus_tag="SLE23_000892"
     CDS             66816..67259
                     /locus_tag="SLE23_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEI8467811.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT        19977 a        13995 c        11788 g        22003 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagctgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactag cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc aagaggttgt gaaatcagcg ttttgacctg agtattagag
    38641 aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata ccgaaggtca
    38701 gctgattgaa caccgtttat tcaaaaaaaa tggactgcga cacgactttt gtcacagtcc
    38761 cttcgtgtgt ttttctgcct tctcaaaagg atgacagttt ctcactcttt tcctatttct
    38821 tctattcaat caaataactc attttatata catctaaaaa ttcacctaga tctgttcttg
    38881 cccctctagg catgaccgct tcgatttgga agcccatttt tcggtaaagg tgtacggctc
    38941 tttcattacg aacttgaacg tcaagctcca atcgaaaaag tacacccatt tccttcgccc
    39001 aactgatgat ttcttctagc ataagagtgc ctagtcccat tccccaatat tcctgcagaa
    39061 tactgatacc gacttctccc acgtgagaca aacgaaattg actgtctgcc ttgacagatg
    39121 ctgttccaat aatcgtccct tcatagattg caagcagcaa taaattatta ttgctttcgt
    39181 atatataatc caactcttct tctaaggttt ctggtggtaa caggagttct gcttcatcca
    39241 aaactaaaaa ttctgtctcc ttattaactt gtcccatcat caaaagaatg tcttttgcat
    39301 ctcctggcac tgcttcccgc aagatgatcc caacttcttc actcatgatt ttcagcccat
    39361 ttttctagaa ttcgctgttt gaaggtttca ctttgctccc cgtatgagat tagtttcaca
    39421 taccgctttt ctaaatctgt atcacttttt tctaaaatca gttccaaata atcctccggc
    39481 agtgcttctt ctaatagatt tccccattca acaacggaaa gcccatcacc ttcaaaatat
    39541 tcatctaacc ctaaatctgc tccgctagct gctacccgat aaatatccat atgatacaac
    39601 ggaatccgac cttgactata ttctctaata atcgtgtatg tcggactttt gatcatttgc
    39661 gttatcccta atccttgggc aattcctttc gtcaacgttg ttttacccgc acctagatca
    39721 ccagtcaata tcagattgtc acctggcatt gcggaatgac caattgcctc tgcgaattgt
    39781 tctgtcattg ttaatcctga tagttcgatc atttttcatc ttctcccgct cttctttctt
    39841 tttgccagta tatcgcgtaa tgaagttttt ttaaagaaaa aatgaactag tcaagaacag
    39901 cagctgctgt ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg
    39961 tgataatcga taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg
    40021 gtttgttcaa gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa
    40081 ttttatagcc gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag
    40141 ctacttctga atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt
    40201 gcaattcgcc gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa
    40261 ctactttgtc tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta
    40321 cttttggttc gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca
    40381 attcttgcgc agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat
    40441 ctcttccacg taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga
    40501 tgatctgaag tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc
    40561 cgtctgcaat ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct
    40621 tttctgcttg ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt
    40681 catcccactt atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc
    40741 tggcatgcgc tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt
    40801 cttctgcttt caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa
    40861 cgattttgat cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat
    40921 gacctccaga cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta
    40981 ttttatctgt atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact
    41041 gcactataac aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg
    41101 ttcttctcct aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa
    41161 gccacgactt gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt
    41221 atcgatcatt ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt
    41281 ttcccgttca tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg
    41341 atgagaatac gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg
    41401 tttagcccat gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag
    41461 ctctttatag atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga
    41521 taagccatga gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac
    41581 ttcttcataa ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt
    41641 ttgggacgca tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa
    41701 ttctgaggac aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc
    41761 ctaataaaaa gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca
    41821 cttgattaat atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca
    41881 aattaattgc atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg
    41941 aaaatgccga ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg
    42001 gtcgaaacta tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga
    42061 tcactttgaa cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga
    42121 ttccaaataa tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg
    42181 aagtagcaac caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg
    42241 cttccatggt ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct
    42301 cagctaagct ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag
    42361 aaaagaatct ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag
    42421 gtccagttgg aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa
    42481 acaatatcga agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc
    42541 acgagcgtgg gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca
    42601 gcatgctgca agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag
    42661 attatgccaa atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc
    42721 gcgcgattgc agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt
    42781 ttcattcagg aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga
    42841 cattccctgt ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat
    42901 gccatgaatg gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt
    42961 tttgagctgt ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc
    43021 ggtgactttt attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat
    43081 caatatcaaa tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt
    43141 tcaggagatt actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt
    43201 attgctgcgg ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt
    43261 tcttaccgac ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag
    43321 gtacatcttt ttagatattc ttttgcatat gatcataaag atgaccactg atcatccgct
    43381 gaccgacaac tttgaagtca tggcgttcgt ataatttttt agcctttgga tttttttcat
    43441 ccacacttag accgatgacg gagcgattag ctttcttcgc caatttaggt aatgcttcta
    43501 ataatcgcga accgatgcct tgtcctctaa aatcttctga tacactgata gagtccaaat
    43561 accattcgtt gggaaacgtt tctttatcaa tgaacaaacg tgtagacgca tctagctgat
    43621 atttctctaa gataggtacc agtggctgat cgatgattga ttcttcttca tctgtataac
    43681 cgtaagcaac tcctgcaact ttaccgtcta tttcttctac gatacctcgt gaataactgt
    43741 aacgataatt tggatcagtg attgcttctt ctaaaatctc taaagtcttt tgttcccctg
    43801 tctgcttcaa aaatggcagt tccatatctt ttagaatcac taagatcaat ggggcgattt
    43861 ctggagcatc ttcttttctc gcaaaacgaa tcatagtttc ctctcctttt ctccattcta
    43921 acatgcagaa aaagaaatcg caaaatcgtt attttaaaaa atcttcaatc ttttcagtaa
    43981 tgaaataacc atgagtaacg attcttgccg cttcagttcg gcaataaggg cagacgactg
    44041 gcatttcttt atcattatgt tcgactacat tattgacttc ttcgtatgca aatttttttc
    44101 cgcaattagg gcatttcatt ttttccatgt tatctcaact tcctttcatc tttactctct
    44161 tagcttactc ttatattgta aaaaagagaa gcaatatcct tcttctatgc agatatccat
    44221 acctgacggt cctgttctcc atctattaat cggactttat aataaggacg ttcatctttg
    44281 actagaagtg tccactcttt cacttttgct tttttcccgt agtagctgac tgcttccttc
    44341 atcgctgctt gcggttgttt gaactcttcc gttttttcta tatcaaaaag atgttctgcg
    44401 gccttttccg tgtcatttcg tacggttgtt ttcccagtgg atggattgac tgctatgact
    44461 tgtccttcac aaaaaaactg gtattcatat gttgcattcg taggattctc caaatctttt
    44521 tcaactgcaa aatgaatagc agatatgtta tgttcttttg tttcgttttt tacgattgct
    44581 gctgcttttt tcaatgagat ccgatattcc tggtcactaa tatcatccat gtgaaaagcg
    44641 gcattgagca gtcccgtcat accggtaatc cctattacga tgagggcagc aacaccaaac
    44701 atcatttttt tcattcttca ttctcctgtt tctttttttt aaagaatatc aagaaatgaa
    44761 cgaatgaaaa atcgaatgaa acgaaaaaaa agtgacaatt ttgttatctt tattcgtgca
    44821 gttctaatgg caatccgtct ggatcaaaga aaaacgtcat tttttttcct gtaaaggtat
    44881 cttctctaat cggttctgat tcgatcccta aggactgcaa ttctgcaatt gtttcttcaa
    44941 tatcgtctac tttgaaagca agatgacgca agccacaagc ttctggatag tttggtcgtt
    45001 gtggcgcatt agcaattcca aaaatctcca attcagcact tcctagtttc agatctaatt
    45061 tatagtcatc tcgttctttg cggtaatttt ctctgattac ttcaaatcct aatttattaa
    45121 cataaaaatc acgtgatttc tgataatctg aaacaatgat ggctatatga tggatcgttg
    45181 taaggttcat atgagcactc ctattcttcg tttaagctcg gatctatatt aatctccagt
    45241 tccattgtaa atgtgtcaga ttgaaaaaaa tagctgtttt tcctttttat aagaaaaaag
    45301 gcaaaaaaaa cagaaagtag gtcctccaag acactcttcc tgttcccaat ataataaatg
    45361 aaagtaagaa attatatttt caagaaaaca aacagaaaat tatcataaca caaattattt
    45421 ataattgaaa gactagtttt ttttcaagaa aagcatacaa tagattgtgt tagtaaatac
    45481 agaacacact acatttagtg tcttaaggag tcctcataca tgaagtcata ttttcagttt
    45541 ttagctcatc agctaaaagg ctggccgcaa caaaattatt atcttttctt tttcagtctt
    45601 ggctgccagg tcatgactct tgtcaatagt cccatcactt ggctgtccgt tattacattt
    45661 atcggtacca cgcttggtgt attgtgtatt ttatccatca atgcggcaaa atcagtcaac
    45721 ggtattttag gtattttgtc tgcgatttgt tttattatcg ttgggttttc agcaaagaac
    45781 tatttaagta tcggtgaaca gattgcttat atgatcacat tggatatccc cgtattgtta
    45841 agtaaagaat ggaatcataa tatggcttca aaaatccgaa aattcactgg aaaaagctgg
    45901 tttatcgcaa tcatcagtac tttccttgtc tatcttgttt caggattcct gattggtcgt
    45961 tatacagatg atcctcggcc gtgggtagat gccattgctt tttctattag cttgactgct
    46021 ggtatcatca gtttcttgcg ttacaacaac caatattact ggtggttagc ttcagggctt
    46081 gctcaaatgg tcctttggta tatttcattt acgcatggat ctgcaagttt ggcgatgttc
    46141 gtgaacagct ctgtttactt gctgaatgat gtccttgcat ttaccgtttc accttggtat
    46201 aaccaaaaag aacgtgaacg tatgcaaaaa atggaagaag aatactacaa cgcacaacaa
    46261 cacgcataaa aaaactgagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    46321 acacgtataa acggcggaat cagaagcaac tccttcggaa ataagctgaa attcacaaaa
    46381 atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc
    46441 agcctctatt ttttatagta attccttcag atactttctt gcctcatcat tgaaacgcag
    46501 tgattcttct aacttctgat aatattccaa cgcttgtttc tgagcttcag taaaacgata
    46561 atgttttcct ttccatttgt cgattgtctc ttgcacattt ccagattgga tatctttcac
    46621 tactagttgc catttttctt ttgagactgt acggtctttc ttatcagcag attgtatagc
    46681 ttctcgttct ttacgcaata cttttaaaaa accatttctg actatccgag gaatgctgtc
    46741 gaagaaccct tctgtaaaac catagtgaca atattgcttc caaataaata gatagatttt
    46801 tggttggatg aatcgttggt ttttcgcaaa atattccatc tgagcagtga cttctggtgt
    46861 tcgttgacgt tttgtctttc tcaacacgga aataaatgtt tcaaaataag cattaggatg
    46921 tactggcact tcttcatata cgatggattg ccaatcttta cgtaaaaatg cgcgatagtt
    46981 gatcaagaat tcttctacat cctttactaa ttcttctgca aagtcgtcaa atagttcttt
    47041 ttttatctgt cgcttttttg actgcccatt gatgtgttca cttattttct tgatttcatt
    47101 ttccaatgct tgataatccg ctatgtaaat cggcatttct acttggcgaa attctgcgag
    47161 ccgctgagct aattttatat ccggtaaata tggctgtttc atccgacgat tttggtacaa
    47221 gacaaaacag tatttttgcc atagtccttc aggaaaatcg atattcttct gcttaagcca
    47281 taataattcg tctaaggcca gatcaacttt tgtcattccc tgatggatcg aagctgccac
    47341 tgtcggagag acatgcaggt gatcggcaaa gtggttgatg cctagtttta ggatctttcc
    47401 ggtttttggc gatttaacga tgtattgcac ttttaattct ctaccacact cacaatacaa
    47461 tttttgctgg cttcgttttg ttcgaaaaaa cggattgatc ttgaagtcag aaaacaccca
    47521 atctgttgca gctaaataat gttcttccat aaaacgagag ctgattagat atcggcggtg
    47581 cttatcgact agttcccgct gttttttcgt taattttgca tagatctccc aacgttgact
    47641 gcttgtgtat tgtttagaaa ttttgatggg atagcttttg ctgatttctt ttggaaacca
    47701 ttcttcaaag acggattgcc attcttccac ggctgtttct ttcctttcta attacaaaaa
    47761 gctggctact aacataacgt tagcaaccag ccagtgtttc ttgctaaatt agtgagttgt
    47821 tccggcattt ccggaaatat cttctttatt ttctactgct gcttcaactg cataagtcaa
    47881 agaagaagca atgtcttcta aagacataga aggcgtaccc actggacgat cgatcacttg
    47941 atcgggtgag aatggcacgt ggatgaaccc acctcgaatt gccgggaatt gtgtttcgat
    48001 caaatgaagc aaacgataca tgatatcatt gcagacaaat gttcctgctg tataagagat
    48061 gtacgctggt agaccatgat cttgtacatt ttttgtcatt gctttgattg gcaatgaggt
    48121 aaagtaagcg gctggaccgt tttcttctaa agccgtatcg aatggctgat ttccttcatt
    48181 atcagggatt cttgcttctg ctagattgat tgcgacacgt tcgaacgaga ctgctgaccg
    48241 cccacctgct tgtccgacac agatcacgac atctggttgg tgctgttgga tggcttcttt
    48301 gactacttga ctgctttttt cgaatacggt cggtacttcc actttgatga tttcagcacc
    48361 gctgatttca tctggcattt tttttactgc ttcataggct ggattcactt tgtccccacc
    48421 aaatggatca aaacctgtta ctagtacttt catctgttgt tcctccgtcc gattgattta
    48481 acatatggtt atcttttatc ataccatttt ccttgaacag cgtaaataaa ggaaacaata
    48541 gtttaaataa cataacagat caaacttaat atattcttat aaaaaaatag tgttccacta
    48601 caatgttaga agaggttgcg acaattattc tgtcacaacc cctctcttct attatttaaa
    48661 tagaatcata taagcaattt ggaaaactag cataaataac gcaataaaca actggttttt
    48721 gatcactccg tatttgtctt tcatctccag catcgctaca ggcacgatat tgaagttagc
    48781 agccatcggt gtcagcaggg tcccacaaaa accgcaagtc aatgcaacca ttcctattaa
    48841 cgctggattc gctccatgac taaatacgaa tggtgcaccg atcccaaccg tcatcacggt
    48901 gatggccgca aatgcattcc ccatgattac cgtaaatatc accatgccaa gagcgtaaat
    48961 gatgatgccg atgttcacat ttccttctgg aacgatcgta cctactgcat tggaaatcac
    49021 tgtcccaact ccagcgcttg taaataccgc acctagagaa gctaaaagca ttggcaacat
    49081 gcttaacggc cctactgtgc ccagcatatc tgctgcatca tctaaaaatg tacttggtcg
    49141 attatctcga gaaaagaaca tcaagattag catggctgca aaaacaccga cgcccacgcc
    49201 gactaaagca cctaaattgg taaatagagc aaacaagatc gcaaagacac cgatactcaa
    49261 agctggaata aaaattttca ttcctagttt gtctgacatt ttttccatat attcttttga
    49321 tggaagccgg ctttctcctt tgctgacttt cttagcaatt gctggtatgg tcatcgcaaa
    49381 gatcaagcca ccgttcacga ttgccggaag ccatcttcct cctgcaataa ctacccctaa
    49441 gaccgtccag aaaaaggctg acccataacg atgaggattg gttttatctg ttaaatttct
    49501 tactccagtg taaatcaata cgagtcccat cacgatataa aggatctcca gtaatttatc
    49561 gcctaataaa atatcaggat ttgtaaaaaa gtccatctta ttgccccttt cctggataat
    49621 atttcttcgc taatttcttt tctttaagat agaagtagac acttgccaca actaaagccg
    49681 tgatagccac tggaacttcc actaaagcaa gctgtcccaa tgttacgtca tatcctagat
    49741 ctttcagtgt tgattggact agcaacgccc ctgctcctcc gatgaatagt acttggccaa
    49801 agaaccagca gacattttcc atagctgaag ccataccttt tagttcttct tcatgcttag
    49861 gatggacttc taaccctttt gattcgatgg tccccaatgc catcggtaaa atgattggac
    49921 gaacaaatcc agcaactcca ccaaaactca cgttaaaagc cgcaaagatc attcgaaaga
    49981 tcccataaat atctacaatc ataccagcag atactttctt gaatcgcttg atcaaggaag
    50041 ccgctgattc tttcagacca tttctttcaa gcgttcctgt tgccaacata atgatgataa
    50101 aaatcgccat cccgcgattg tttacaaaac ttgtacctaa aagttctaac attccttgaa
    50161 tgccaagacc gccagtcaaa gctgtaacaa ctaaagcaac cattacgatc aatatcgagt
    50221 ctaatttaaa tgcaaacccg agaataacaa tcaagacgcc taaaaggcta agataatttt
    50281 ccatatattt tcctccataa aatgacaata tttttttaat tataaagcaa aacacataaa
    50341 aaatatagtt gttttctcac gaaatagaca ctatttttaa atatttttcg ttattttttt
    50401 atcacaaaaa ttatcttact tattgtaagg taaagctttt tttaatttat tgcccgataa
    50461 tatatagaaa taaggtctag ttactgtttt ttttaaatga ttaataaata acaacttctt
    50521 tctatgaaat tgcaaagcat tcatcttctt ttccgctaac gatatatccg tcagtgcttg
    50581 gtacacttta ctaaaaagta tgagattgcc gatatctgga taggtgtgct atactacaga
    50641 aaaagatata caatctgcca ccgggtagga taaagaggat gatcattcca ttaggtcttt
    50701 gaagggatga ttttcctctt tttgtgtatt tttttatagt taaggaggaa tgtaagtatg
    50761 gcatggatgg aattaatcat agcaggaatt ttggaagtat tctggtcaac gatgatgaaa
    50821 tggagtgatg gtttttctaa aatcaattat tctttttaca cagtgattgg catgattgct
    50881 agtttttact ttttgtcaaa ggcaatcaaa agtttgccga tgagtctctc ttatcctatc
    50941 tggacaggga ttggcgcagt tggttcggtc ataattggtg tggtcttgtt tcatgataag
    51001 ctgaatcttt ccacttggtt ctttgtgggg atgctactca tcagtatcat tggcatcaag
    51061 attactagcg gccactagac acttggaata agtactgatc agaaaaaata agccttttta
    51121 tttaatattc aattttttta tgaaaaaata agaaataagt ccaatgacct agcgacttct
    51181 ccactcatca ggtgtatgct tgtactatct atagaaaagg agtgaatatt tttgaaaagt
    51241 ctttcggtcc aagaattatc caagaacttt ggtcacaaac aagccctcag cgatgtcagt
    51301 tttagcttat cccctggcaa aatcgttgga ttagtaggtc ctaatggcgc tggaaaaaca
    51361 acgatcatga aagctatttt aggactgatc cattactcag atggaacaat ctgtattggt
    51421 gaaaatgaga tttctccctc tagtcataaa gggttggaac aagtaggagc attgatcgaa
    51481 tacccgggta tctatccatt cttaacaggc tatgatcatc tgaagttatt ctctgaaacc
    51541 aacgatgtat ctgctatcga cactatcgtg aatcagctca agatggaaaa gtacattcac
    51601 aaaaaagcga aatcctactc gttgggaatg aaacaaaaat tgggaattgc tcttgcctta
    51661 ctgaaccatc cgtctatcgt tattttagat gagccgatga acggtttgga tccacaagca
    51721 acaagagatg tgcgaaaaat cattaccgac ttggctactc agggcacctc tttcttgatc
    51781 tccagtcact tactcagcga gcttgaaaaa atggtcgatg agctgatcct gatcaatcaa
    51841 ggaaagatca tcaaacaatg tacaatggct gaattgaacc aaacagcgca agatttcatc
    51901 gttatctcta caacaaatga tctagctgct cgaacgatct tgacagaagc tggatatact
    51961 ttggaagatc ctgataaaat caagctttta aaagaaaacg aagaattatt aggaaccgtg
    52021 atccagctat tgtctgcaca aaatatccat gtgacagacg tccagcatct gacgaatgat
    52081 ttggaatctt ctctattgga aattctggat tcagtaaagg gggaagaaga aaaatgacat
    52141 tgcttgtaaa acaagaatta tttaaattga tcaagaaaaa gtcaactgct gttttatctg
    52201 ttctattagt tgttttgctc ataggaacag cacttctagc caaaaaatac acgacgatca
    52261 ttgatccagt tgaaatgact gctcagcttt ttagtgccac atcttggatt gtctttatca
    52321 tgattgcagc tgcaagcacg atcatttcga tggaagcaca atatggtaca ttgaaaaatc
    52381 tcctttatcg aaagtattct cgaggagaaa tattagtaag caaatggatc acattagtta
    52441 tttattctgt ttatttatac cttttagcta ttattgtcac tgtgttgatg aaactgattc
    52501 ttttcccttc gatttccttc acggagaagg tttctactgg tcaaacactg atccaaagct
    52561 tgttcactta tactttgggt agttatatcg gtttatggct gattttaagt ttagtgttga
    52621 tgattgcttg ctttatcaat agttccggcg catccatctc agcaggaatc gtcttttatt
    52681 ttgcttcgtc aatcatatct ggtatcctta ttgcactcat ccaaaaatgg gagtggatca
    52741 aatggaatcc gatcagtatg ttgaatctgc aaaaccaaat tggaaacgaa gagatcatga
    52801 agcaattgac tcatctttct actaatcaaa tgctattcgg taatttagct tacatcgttt
    52861 tgttcttagc attaggatat ctcgtattta agcgaaaaaa tgtatgatga ctcatcaaaa
    52921 aagaggctgt gaaagagacg ttcagcctta ttgccgattg gctgtctctt aaacaccgtt
    52981 tattctgaaa aaggagctgt gacaacattt gtgtcacagc tcctttccta gtatgttttt
    53041 gaataaacga caggctcaca acctctcttt atacttcttt tatacttcta tacgtgaagc
    53101 atcccagtgg caaataaaac cattgcaatc actccgacca tcgtcacacc tataagtaaa
    53161 atcttatcta agtggatatg ttgtacaggc tcgttttgct ccttacgtgc tttgaggtaa
    53221 aaataaatgc ctggcaagaa aagaacaaga acaagcatta cttcattaaa ggctacgact
    53281 agcatagccc atacttgaaa ggcacttgct aaaagcccta ctaaaaattg gacccattct
    53341 ttccgctgat aagaaagttt catttggtac aatcctaaga aaagccacgt gaagaaaata
    53401 gctgctgtac caagtgtgta agcaaagtta taagcactgt cagtgaataa taatgaaagt
    53461 aaaaagacat tcgtacataa cgtcgtcaat acgatagcat aagttggtgc cccatttttg
    53521 ttgagttttc cccatgcttt aggcaaaagt ccgtcttcag ccatgtttcc cattgtttca
    53581 atcggtaaga tcgtccatga gagccaaaca ccaactaaag aaatgatcaa accgccgttg
    53641 atcacgactg ctccccattt accaaccatc atttcaaaca catagcccat agcaggctgc
    53701 gccttgatcg tttgcagctg attcatcgtc attgtcccat atggaagcat ggaaaccaag
    53761 acgtaaataa taatcaagcc gaatatccct agaatcgttg ctttcccaac atctgattgt
    53821 ttttttgctc gtgaacctac gacagaggct ccttcaatac caacaaatac ccaaagcatc
    53881 accatgatgc aactcaatac ttgactggaa aacgggatcg gctgtccatt cgcattcaat
    53941 ataatgtcgc tagaaaagtt atcaatgaat tgttggatcg aaaacgtgct gatagctact
    54001 acaataaata aaaataatgg cactaattta cagaatgtga cgatagcatt gacgaaacta
    54061 gcattttcga ctccccgatt cactagccat gcatatcccc ataaaaagac tgtactcatc
    54121 acgatcgatg ccagattttg cccaccttca aatactggga agaaatatcc taatgcgctc
    54181 atcaacaatg ttgcaaaagc tacgttgcct aaccagcatg tgagccagta accccaaccg
    54241 ctgataaaac cagcgaaacg gccaaaacct tcttctgcgt aactaaagat cccgcctttt
    54301 aaatctggac gttttttatt gatattattg atcgacaagg agagcatcaa cattgctgtt
    54361 cctacgagta cccaactgaa aatagctggg ccgccagccg atccggagat gtccgtcata
    54421 ataccaaata cgccacctcc aatcgctgaa ccaattacta aggcagcaag tggaattaaa
    54481 ccaattcctt ttttctgttg ctctgtatcc atgtaagcat cctccaaaat aaaaccgctt
    54541 ttatcaaaaa gtataacaaa ccttttttat ttttacttaa ttaataaaaa ctttaataga
    54601 aatataattc taccggcttt tttctcatta tacaagcaaa gcgcctagtc cctttccaaa
    54661 ttacaccacc aaaaaactta aaaaagatgc tatactaaaa ggaaagaatt ggaggatgat
    54721 ccatgaacat tttatatata tcgatttcag gaaatacgcg tgcctttgcc aaacatctag
    54781 cagaatatgc tgaaaaaatg catgcagaag atcctgtcaa tcctgaagtt actttaaaag
    54841 aaatccatga aaatagtgat tttacgaaag aaacagaacc attttttact ttcgttccta
    54901 cttatttaga cggcggaaat ggtttagata acggtgatac agaaatcttg accgaaacga
    54961 tgcgtgaata tctggaacat gaagacaatc ataaactttg tcttggtgta gtcggtagcg
    55021 gaaataaaaa cttcaataat cagtattgtc taacagccaa acaatatgca caaacatttg
    55081 gctttccttt cttggcagat tatgaattac ggggaacacc atctgatgtg acacgaattt
    55141 atcagatttt agcagaaaac aataaataat aaaaaagaag aagctgaaaa atagatttca
    55201 gtttcttctt tcgtttctat tgtttctatc atattaagct ttgacatcca tcacaggtgc
    55261 ttttgctttt gctttacctg ttttttccaa gacaaagttt tttacacgat ccatattggt
    55321 taccaagacg atcatggatg tttctttgcc tgctgctttg atcgcttcta agtcagcttc
    55381 tgctacaagc gtatcaggtg tcacttgctg cccttctgtt actttcacat caaatggcgt
    55441 accgcctaag tcaactgtgt tgattcccat atgaagcaag atttctaaac catttggcgt
    55501 tgtgatccca atagcgtgtt tcgttgggaa gacagagctg actaccccag taactggaga
    55561 atagatatgt ccgttttctg gttctacaaa gtagccttca cccatcatct tttgtgcaaa
    55621 aactggatca cttgctttat ctaaagaaac aactgttccg tcagcaactg atgagaggat
    55681 agtcacactt tcagctgaag tttgaggtac tactttttca ggcacttcat ttactgtggc
    55741 tgtttcagtc gctaattctt ctttttctaa acggtcttta ggaataccga agaagaatgt
    55801 agcaacgaag ccaccagcat aagctgccaa taatccaagg atgtagccta accatttacc
    55861 gtcagagatc aatgggatca aagcggctcc tgaaggtcca atagcgatag ccccgacatt
    55921 tccgatcatt ccgatcactg ccccgccgat acctccaccg atacaagcag taataaatgg
    55981 gcgtcctaga ggtaatgtta ctccgtaaat caatggttcg ccgattccta ggatcccgac
    56041 tggtaaagct cctttgatca tttctgttaa ttctttatct tttttgcagc gaatccataa
    56101 tgccaatgct gcacccactt gtcctgcacc agccatcgca agaattggaa gcaatagcgt
    56161 acgaccagtt tcatcaatca tttgcacatg gattggagtc aaaatttgat gcagtccgaa
    56221 cataaccatc ggcaagaata atgtgcctag aacgaagccg gcaaatgctc caccaacgcc
    56281 aagtacccag ttgatcccac cgaccatgcc atcagaaatg aaacctgcta aaggcatgat
    56341 gaagaaaatt tcaatcagac cgatggcaat caacgaaaga gttggtgtaa cgatgatatc
    56401 taccgcatca ggtactactt tatgcagttt tttctcaacg attgacaata gccaaacagc
    56461 gaagatgaca cctaggatcc caccttgtcc agctgcaaga gcttcaccag taaataagtt
    56521 tttcagtggt gcttccggat tcatccctgt cagcatcaca acggccccga taactccacc
    56581 aagagttggt gttgcaccaa aaacttgtgc agcattgata cctgtataga taactaggta
    56641 gctaaacatc ccgtttttca agatgttcat cacatcgata tattgttgcc atgttgctgc
    56701 atcaagtgtt ccggctgtga ctaagtttgc taaaactgcg gcaatccctg ccacgatccc
    56761 agtaccgaca aatgcaggaa tcattggcac aaagatatta gaaatgtctt ttaataccga
    56821 tttgatttta gatggttttt gtttcgattt ttgtgccgct ttcatttctt gtgcccgttc
    56881 gtttacacgg tcttttccag atgctgatga atttgctgta gctgtactta cagaagaaag
    56941 tttttctcct aatttcacgc ctgccaaatc aaccatttgc tgtgctactt tgttcacttt
    57001 cccaggtccg atgatgactt gaagctgttc atcttctact acaccaagca ctcctggaat
    57061 cgcttttaat tcagagacat ttacaagatc atcattgatg atcttcatac gcacacgagt
    57121 catgcagtgg acaatgcttt ctacattgcc catgccgcct gcccctttat aaatttgttt
    57181 tgccagttct tccaaagtca gttcgttttt tgccatggtc ttttccccct cataaggtcc
    57241 cttttacaaa tccgtttgct tcagctaatt ttgcttgagc ttcctcttta tcactatttg
    57301 tcaaaatcat gacgatagcc agcttaacat tttgatctgc ttcttcaaag tacttttcag
    57361 ctgtttcgta atcagcttct gtcgcttgca tgatgattcg ttttgagcgt tcgattagtt
    57421 tttcatttgt tggtttgaca tcgaccatca agttattgaa tactttacct ataccaatca
    57481 tactgatagt agaaatcata ttcaagataa gtttttgtgc tgttcctgac ttcaatcgag
    57541 tagagcctgt caaaaattct ggacctgcat cgacttcgat tgggaaatcc gcgtgtttac
    57601 tgatttcggc ttgtttattg caagaaatcg ttcctgtgac agcaccgatc gattttgcgt
    57661 aatctaatcc accgatcaca tatggtgtac gaccgctagc tgcgatacca ataactatat
    57721 cattttttgt caaattcagc ttgattagat cttcttgccc tagctcataa gaatcttcgg
    57781 ccccttcgac agctacagtc attgcttctt ctccaccagc aattagacct atgaccattt
    57841 ccggttctac accgaatgtc ggtacgcatt cagcagcatc taacacacct agtcttccac
    57901 ttgttccggc tcccatataa atcagacgtc cacctttttt aaaggactca atcgtgttag
    57961 caatcactgg ttcgatactt gtcagttctt tttcaaccgc agcggccact ttctgatctt
    58021 ctttgttcat tagttgaacg gcttgagaaa tactcatctc atctaatcca aaagtttctt
    58081 ggtttctgcg ttccgttgtt aggttctcta aattgatttt gctcattttt atcttccttc
    58141 ttttcttata aattgatagt tcataccagc tttgatttgg ttgatcaatg gtagctcttc
    58201 tttgataact ttagctacta cattcacttt ttcatccgct ggcaaatcat atttggttaa
    58261 ttggatctca cccatatagc gcaaatactt ttcgttatct aaagtaatag accctttcat
    58321 acgcgtagct gtatttcttg ctgggatagg cggaatctct cgaaaacgtg catctacgct
    58381 tcgtatgaca tctcttgcat cgtcttgccg attcgtatgc ttccctaata tatattcgta
    58441 aaattcttca tctacaggtt ccgtatggag caagactgtc tgttcttttt ggaaagaagc
    58501 aaattgctcc tgaacgtttt ctgacagacc tgcatctccg atgtaaacaa tatccgtgtt
    58561 acttgctaat agatctagag cgcctgcaag aggatggatc cctcgatgtt cttccaaagt
    58621 tggcaatcct tgatatagtg ggcctctcaa ctctgtatct cctggtacaa aaccttggac
    58681 aaggagacct tgaattttga gccattgatt ttttttctga taccattctt tgtccagccc
    58741 tgtttcggga cgtggataat aattatgcca agcttcaatc tgtgagaaat cagcttctgc
    58801 ttctttcaat tcatcgatat ctttaggcgt gatcgtgcta gcattcaaac tgattttcaa
    58861 ttgatgtgac cagtcggcaa tctgctgatt ggaaatatga taatccattc ttaaacctgt
    58921 tacaccaatt gctttcaaag gcgttagatc ttctaatgaa aaacccgctc gttccaatgc
    58981 ctctcctgaa atatcgacca tcaattctag tttattcttt ttcgcttcgc ttcctagttc
    59041 gatcaatcgc ttttgatatg ccgaaacatc atcttctggt atatgcatgg aagtgaaaat
    59101 accgacaaag ccattggatg ccatttggcg gatatactgt ttcttctctt ctgacaaaga
    59161 atcgttcata aatattgaaa agccaaacat attatccctc tttttctgta tccgtcttca
    59221 tttctatgac tagagtatat atctaaagaa acaaaatttc aatactttta ttaaaataat
    59281 taaatttcat ttctaaaggt tgagtttata ttatcaaaag aattgtcata acctaaaaaa
    59341 ggcactgcta agcaaaagca gtgccttgaa atattttatt taaataacac aaaaacataa
    59401 ttactcataa gaaaccaatt ctgtattatc taccatgaat gtaaagaacc cctcattagg
    59461 catcggatga aaataagcat tgatcactct tatcaaggca ttatggcaaa ctaacagata
    59521 gacattttct tcgtcttcga tgcattcttt caataaagga acgatccgtg catacacatc
    59581 taagactgac tccccatttg ggaatcgtac agcgaacgct aaacgtgctt tttgaaagtt
    59641 ctcatctttg cttggcagtc catcataatc cccaaaatcc atttctacca atcgttcatc
    59701 aacggtcagc ggcaagctga gacgatcagc aactgcttgt gctgtatctc ttgctcgttg
    59761 aagaggggaa tggatgattt tcgtgattgg aacaggcaaa tctactacct tttctgctag
    59821 tttctgtgcc tgcatctgtc ctttttcagt cagcggcaca tctgcccgtc cgcaaactaa
    59881 tccttgtgcg ttccaagttg tttctccgtg tctcgttaca taaagcatgt gattctctcc
    59941 ttcgttggca aagttcccct taaccatacc ttgttgttct tgagattaca agggttagat
    60001 tctctcaaga gaaataatct cagtagatac tttatccagg aaggtttgat catgttccac
    60061 tagtaacatg gcaggtttca cgttcaagat cagttgttct aattgttctt gattgaagac
    60121 atccaaataa ttcaatggtt catcccatgt atatagttca gctggctgtg ataaagattt
    60181 agccaattcc acttttttcc gttggcccat actcatctgc tcgatcttgt tatgaaaaac
    60241 atctctttcc atcccaagct ttcggaggtt gttcaaaaat gcttggtagt ctacttggtt
    60301 tttctctgca aattccgcca acgttcctcg attgtcttca taattttggc ttgcataact
    60361 aatgctcaga tgttttggct ggtatttttc tcctataacc ttgccgttga atgcccccag
    60421 aagataatgg ataatggatg actttcctgc accgttagga cctgaaatcg ccacccgctg
    60481 atgaggctcg attgtaaaat gaattggctc gaataacaga ttttcatacc ctaattgaag
    60541 atcttctacg cttaaaagtc gcttatggtg agacgcttgg ctattcatcg tcaaagaatc
    60601 gatatattcg atatctttta atagtttttc tttctcgctg atctgggtct ccatccgatt
    60661 cacgattgct ttggatcgtt tcatcgtccg tgcagcatca gcacccactg ctcctttatt
    60721 cactcgtcta gattcagtat cgatgaatcc gacttgtttc tttgttttat ctccttctcg
    60781 ggaacgagac cattcggctt tttcagctgc tgttttcttt agcctactga cttctttttt
    60841 caatttttca ttttgagcca tttcaaattc atcacgaagt tttttctgtt cttcatagat
    60901 agagaaattc ccttgataaa gttccagttg acttttttcg attgctaaaa catggtccac
    60961 tacttcatcg ataaatcccc ggtcatggct gaccacgatg aagccttgtt ttttcttttt
    61021 caaataagcc gctacttgtt ttctaccaga gatatccaaa tgattcgttg gttcatcgat
    61081 taacgggaaa tgagtgtcat ccacaaataa aagtgccagt aggacttttg tcttctctcc
    61141 ccccgatagt gtgctgaatt ctctccataa gatttcagga tctgtttgca tcaattggag
    61201 ctctctttcg atttcccata tctcaaaatc cgtaatatca tttaacacgt aataggttaa
    61261 acgttcttta tcttttgtct gttgcgggaa ataggcaaat tcttgctgat ggattacttg
    61321 cccttgataa ggtagtttgt tttgtagaat attcagtaaa gttgtctttc ctcgaccgtt
    61381 tcgtccgata agtcctagtt tccattgtgt gtcaaaattt agatttgctt gttcaaataa
    61441 taatgtgcct tggctgtcgt agccgaatgt cagatttttt atttcgattt tagacatttt
    61501 ccatcacctc gtaaaaaaag accagtccta ttttcagaac tggctaaaga ggatgcaagg
    61561 gttggataca cacaaaaaga cccatacatc gaaaaaacca agccaatccc gaaaatctgc
    61621 acactgcttc cttgtctcca caaggtacag tctgaatgca gctttcatca atcgacttaa
    61681 tttttcaatg cacggatccc tcactttgtc ctatatttga aattacgata gcataaagaa
    61741 aatgattttg tcaactactt cgggaggatg gtgaaaaatc tgctaagtgt ctgtcctaag
    61801 atttttgttt tttctaatgt ttgcctgtgt tccattgctt cttctaaacc tattggaccc
    61861 aaatgaatac ttaagacaat tgggagaaaa tcagaaagtc cttctagctc ttggtctcta
    61921 cttccgcaaa tagcgattat tggttttcga tatttttttg caagcactgc tacaccgtat
    61981 ggaacttttc cgtggatcgt ttgctgatcg atccgccctt ctcctgtaat gatgacatct
    62041 gcttgttcga tctttttttc caatccagtg atttggctga ctaaatcgaa accagaaacc
    62101 atcttcgctc ccaacaaaaa aagggctcca ccaataccgc ctgctgctcc acttcctgga
    62161 atatcatcta aatccacctc ccagaaatct tttatttgct gagcaatctt tcctgcttgt
    62221 ttatctaaga aagctagcgt cgtatctatt cctccttttt gtcttccaaa ttgccaagca
    62281 gctccttgtt gacctgtata tggattggta acatctgcag cgataatcaa ttttacttta
    62341 gaaacaagaa cgtttcttcg atcaaaatga agttttttag tagataataa aggatttcct
    62401 tctgtgtacc cttctaaaga agcacccaag gattggagta atcctagacc accatcgcta
    62461 cacccgcttc ctcctaaagt gacaataatt tgttctactt cttgaagcag tgcatcttta
    62521 ataagttctc ctaaggcata actggaagca agtcggatag tttgatccgt tggtttatca
    62581 agtagatcta accccaatgc ttgtgcagat tcgatgactg cggtgttttt tccttgccaa
    62641 gttgtcaata aatagctgat ttttcgctga cggaataaga gatccatccc atcaatggta
    62701 cgccatgttc ccctgagcgc gtaatagatt gcttctgcag tattttctcc gccatctgca
    62761 atcggcacat tgatttttct tcctttacga tcttcccagc catttagaac tgcctgattt
    62821 agttcaaatg aagaagcact tcctttaaat gaatcaattg ccgccaaaat atccatctgt
    62881 atccctcact ttcttcttaa gtaagacact ttttttcatt tttttcaaac aaaacaatgc
    62941 tattttcttc catttttcta tatactaaaa gggaactcat tgaataaagg agagaaaaaa
    63001 catgaaaatc gcaatagctg gggccggagc aatgggcagc cgaatcggat tgatgctaca
    63061 tcaaagcgga aatgaggtcc tcttgatcga tcgttggcct gctcacattg aagccattcg
    63121 tacaaatggg ttgattgctg actttaacgg taaagaagtg gtcgcaaaac tgccaatcta
    63181 ttcaccagaa gaaatcatcg aaagcaacga acacgtggac ttgatcgtag cattaacaaa
    63241 agccaatcaa ttagatgata tgttttgttc gatccaatcc attattactg acaatactta
    63301 tgttttgtgt ttactaaatg gattaggtca tgaagatgta ctggaaaaat atgtgccaaa
    63361 gaaaaatatc ttatttggga tcacgatgtg gacagctggt ctagctggtc ccggaaaagt
    63421 cacattgtta ggtgatggag aaatcgaact agagaacttg gaaccagaag gcgaagcatt
    63481 tacaaaaaaa gttgtagaag tctttcaaga agcaaattta aatccgatct atagccataa
    63541 cgttcgttat tccatttggc gaaaagcttg tgtaaatgga acattgaatg gtttatgcac
    63601 gattttggat tgtaatattg ctgaactagg cgcgcaaaaa gcggcagaga gcatggttcg
    63661 aacaatcgta tctgaatttg cttctatcgc agcaaaagaa ggaatcatac tagatcaaga
    63721 agaagtgtac caacatattg cttctactta tgatcctgac aacatcgggt tgcattaccc
    63781 atctatgtac caagacctga tcaaaaacca tcgtttgact gaaatcgact acatcaatgg
    63841 tgccatttgg cgaaaaggac aaaaatatga tattgctaca ccatattgtg cctttttgac
    63901 ccaattagtc catgcaaaag aaggaatcct tggcgcagaa taaaaggctc tctgatgaga
    63961 atcagctgaa tcagcagctg gttctctttt tttaagccca ataaaagatc aaaaagaaaa
    64021 cacaactctc atgatgccat aagaattgtg cttgtttgtt tcagtacata atctcttcaa
    64081 aatgtaggtt ttttatttgt tttcaacaga ggagaggtca tattcgtatt gctcataaat
    64141 agtggaatcg ttagtgataa atcgttttgc ccaattttct gcatcataaa attccaatag
    64201 ctctgatagg attggcttaa atggtgtatg cagaaattcc ggtaattcat ctaaatcacg
    64261 ttctcgaagc aaaaaaatat tttcaggacg ataaaaatga taatgagcaa tcgcttgatt
    64321 atccgtcact agtttctttt gaaaatacat ggattcaaat gtccgcaaag tcactccttg
    64381 ctgaccctcc cgcaacagtt ccagaatccc gcgcgattcc cctgtttttt tcaggtactc
    64441 ttcataagta agatatccag gttgttcatt ccctcgatgt ggaagaatga aatagttggt
    64501 cgtaacatct ctttttataa attcctgctt atagctttct gctcgttctt ttctcccatt
    64561 attcgttgca ccaaaaaata gatccgtctt tggttcgcta gaagaaaaat tcatatgttt
    64621 cgaataaaat gaactattat gtttcagccc aagttctttt gcttccaaaa aatcaaaatg
    64681 ataaatctca tcgattgccg gttcatcttg tgcctgcttc agcatcgcct cgtgttctgc
    64741 tttgaagtga ttccaaaaaa ataacacaat ttttgcattg gtaaatgggc gcacgcgtcg
    64801 agccatctcc atatcaaatc cataatctaa aaaaacgatc agctgataat ttgccaactg
    64861 ttgtctagct gatttaatga attccgactg tagtaaatct tttccggacc aaacatctaa
    64921 agagcggatg gaaggcaaaa aataaagtga tttatttttt gcaactagca gtacgtcatt
    64981 tttgttcatc ttttccgcct cactttctct gtcacttttt cctatgatag cctgtttaaa
    65041 tagtaaaaag ccagtaaaac gtttcctata tttgtatgaa aatttaacat ttgtatgaaa
    65101 atatgatgaa ataaatcatt cttctattaa aattcgccta aaagttttct gaatagttgt
    65161 aattgtctga aaatttgtta tcattagtca ttgttaaata ttgctattta ttcttaatat
    65221 aaattttgat tgtgaattta aaagaaagag gtcatttatg gaagataaaa aattgaaaaa
    65281 acaacttagc tccagacata tcaccatgtt agctttaggt ggagcaatcg gtgcaggtct
    65341 atttaaagga agtggcgaag cgattgggat cgccggccct tctgtattga ttgctttttt
    65401 gattggtggg ctgattttat atatcgtgat gaaaggtctg ggaaaaatcg ttttaagcgg
    65461 tggcgacacg catcacggat tatctggttt gatacgccct tatctaggtg ctcattctgc
    65521 tgattttact gattgggtct actggtctat gtggattatc aatatcatcg ctgaagctgt
    65581 tgcagctgct tcctttttgc agttgtggtt cccgcacatt ccagcctggg tatttgtttt
    65641 tatgttggct gttttaacta cgatcatcaa tctttattcg gtacggttat tcgcagaaac
    65701 agaatattgg ctggcttttg ctaaaatcag tgtcattatc ttactgatca tttttgctac
    65761 ttatcttgtc ggtcagcaaa tgttgggcac aggcgttttc cctacccttc agcaattgac
    65821 tgaccatggt gggtttactc ctcatggtat gaagggaatc atcagttctt tgcttgtagt
    65881 tatctattct tacggcggtt ctgaactgat tgctatcacg gtaagcgaag cagatgatcc
    65941 taaacgtgcg attcctaaag caatcaaagg tgtcatggga agaatcattt ccttttacat
    66001 cattcctttg tttttgcttt tgattctttt tccttggaat actttagcag gcacgaatgt
    66061 cagtcctttt gtgatggtat ttgaaaaaat gaatatccca tttgcagcgg atatcgtcaa
    66121 ttttgtgatt gtccttgctt tgttctcatc tatcaattcg ggtgtgtatg catcttcaag
    66181 aattttgttc ttccgtttga aggatcgaaa aggttcctct agaaaactag ctgttttaaa
    66241 caagcatcaa gtaccgcaac gtgctgtttt attttgtacc agtgttcttt atcttggtgt
    66301 agctctttct tattttgtcg gtgacaaatt atttggctat ctggcaggtt ccctttcgta
    66361 tacagtatta ttgatctgga tcattatcag tgcggcatcc tttgtactgg cactaagaaa
    66421 aggaacatta tgggataaag gaatcagctt ttttgcatta gctgtcttag gattgatttt
    66481 ccttggtatc ctgttcacga actccattgg ggtaactgta ttgactggcc tgctttacct
    66541 gttcatttat ttcagttatc aaaaaaagaa tgatgcgttc gtattgacga atgaatgaaa
    66601 tcgatagaaa attttatttt atttatgtgg aatagatgga gctattgaag aaaggagttg
    66661 tgacaaaagt cttgttgcaa ctcctttttc cgaataaaca gtctcatgac ctcttggtaa
    66721 acggtgttca aaaaccctct gtgcaaaata attgattgtt ctccatgctc atgacatgat
    66781 agaagaaagg aatgaaaaaa aggagtttgt tttaaatgaa aaagtattgg aagtttttgt
    66841 tgatgatcgg tgtttcaacg gtagttatgt ttggtatgat gtacttgaat gtctatgcgc
    66901 tcgatcatat cttcttcagt cgtacacgag tattcatggc gttgatgatg ggtgcagtca
    66961 tggcagtcat catgctgttg ttcatgtgga aaatgtatga aaacaaaaag ataaatgtta
    67021 tgatcttagc cgctagtctt cttgtttttg ccggttcctt gtttatggta cgaagccaaa
    67081 ctactgtcaa cgacacagct tggatgaagg ccatgattcc tcatcattct atcgctatcc
    67141 tggcaagtaa acgagctgat ttaaaagatc ctgaagtaaa aaaattagcg gaagaaatca
    67201 ttcaggcaca agaagaagag atcgacaaaa tgaaaaaaat gatcaaagaa atggaatgac
    67261 cattatccgt ccaaataaaa aaagaggatg ttccagaagt tatcagcttc aagaaataag
    67321 aagaagctac ttctggaacg ccgtgaataa ggggttgtga aaaagctgcc ctgcatcaag
    67381 taataagaac agccaaacaa aaatagcttc tcctattttt cgtttggtta ggcttattac
    67441 cgcagatgca agcttttgaa caccgtttat taagaggttg taaaatcagc gttctgacct
    67501 gagtattaga gagacaaatg gaaaaatagt tcctcatatt ttgccatttt ttgagctaat
    67561 accgagggtc agctgattga acaccgttta tcgagaggtt gtgaaaaagt cgcttagttt
    67621 cgcgtattaa gaaaaatttt gtgaaatggc tttccacatt tttgtataaa tttggcttaa
    67681 taccgagaaa ctggcttttg aataccgttt attcgtaaaa gggattgtga caaaagtctt
    67741 gtcacaatcc ctttttatgt ttt
//
LOCUS       DARPZJ010000011        65562 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.011, whole genome shotgun sequence.
ACCESSION   DARPZJ010000011 DARPZJ010000000
VERSION     DARPZJ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.011"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(23..391)
                     /locus_tag="SLE23_000893"
     CDS             complement(23..391)
                     /locus_tag="SLE23_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HEI8467812.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1002..2393)
                     /locus_tag="SLE23_000894"
     CDS             complement(1002..2393)
                     /locus_tag="SLE23_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HEI8467813.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2606..2992)
                     /locus_tag="SLE23_000895"
     CDS             complement(2606..2992)
                     /locus_tag="SLE23_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEI8467814.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3048..3671)
                     /locus_tag="SLE23_000896"
     CDS             complement(3048..3671)
                     /locus_tag="SLE23_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEI8467815.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3735..4403)
                     /locus_tag="SLE23_000897"
     CDS             complement(3735..4403)
                     /locus_tag="SLE23_000897"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEI8467816.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4415..4855)
                     /locus_tag="SLE23_000898"
     CDS             complement(4415..4855)
                     /locus_tag="SLE23_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467817.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4914..5585)
                     /locus_tag="SLE23_000899"
                     /pseudo
     CDS             complement(4914..5585)
                     /locus_tag="SLE23_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5770..6168)
                     /locus_tag="SLE23_000900"
     CDS             complement(5770..6168)
                     /locus_tag="SLE23_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HEI8467818.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6165..6938)
                     /locus_tag="SLE23_000901"
     CDS             complement(6165..6938)
                     /locus_tag="SLE23_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEI8467819.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6935..7618)
                     /locus_tag="SLE23_000902"
     CDS             complement(6935..7618)
                     /locus_tag="SLE23_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEI8467820.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7785..8672)
                     /locus_tag="SLE23_000903"
     CDS             complement(7785..8672)
                     /locus_tag="SLE23_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8467821.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8669..9538)
                     /locus_tag="SLE23_000904"
     CDS             complement(8669..9538)
                     /locus_tag="SLE23_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8467822.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9675..10961)
                     /locus_tag="SLE23_000905"
     CDS             complement(9675..10961)
                     /locus_tag="SLE23_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8467823.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11234..11812
                     /locus_tag="SLE23_000906"
     CDS             11234..11812
                     /locus_tag="SLE23_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEI8467824.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11812..12741
                     /locus_tag="SLE23_000907"
     CDS             11812..12741
                     /locus_tag="SLE23_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8467825.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12738..14474
                     /locus_tag="SLE23_000908"
     CDS             12738..14474
                     /locus_tag="SLE23_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEI8467826.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="SLE23_000909"
     CDS             complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="SLE23_000909"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEI8467827.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15370..15879)
                     /locus_tag="SLE23_000910"
     CDS             complement(15370..15879)
                     /locus_tag="SLE23_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEI8467828.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="SLE23_000911"
     CDS             complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="SLE23_000911"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEI8467829.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRCIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17180..18271)
                     /locus_tag="SLE23_000912"
     CDS             complement(17180..18271)
                     /locus_tag="SLE23_000912"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEI8467830.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="SLE23_000913"
     CDS             complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="SLE23_000913"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEI8467831.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="SLE23_000914"
     CDS             complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="SLE23_000914"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEI8467832.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="SLE23_000915"
     CDS             complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="SLE23_000915"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEI8467833.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22234..23208)
                     /locus_tag="SLE23_000916"
     CDS             complement(22234..23208)
                     /locus_tag="SLE23_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HEI8467834.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23189..25072)
                     /locus_tag="SLE23_000917"
     CDS             complement(23189..25072)
                     /locus_tag="SLE23_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HEI8467835.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(25090..27315)
                     /locus_tag="SLE23_000918"
     CDS             complement(25090..27315)
                     /locus_tag="SLE23_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEI8467836.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27430..28464
                     /locus_tag="SLE23_000919"
     CDS             27430..28464
                     /locus_tag="SLE23_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8467837.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28531..29544)
                     /locus_tag="SLE23_000920"
     CDS             complement(28531..29544)
                     /locus_tag="SLE23_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8467838.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29622..29810)
                     /locus_tag="SLE23_000921"
     CDS             complement(29622..29810)
                     /locus_tag="SLE23_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HEI8467839.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30250..30378)
                     /locus_tag="SLE23_000922"
     CDS             complement(30250..30378)
                     /locus_tag="SLE23_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEI8467840.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="SLE23_000923"
     CDS             complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="SLE23_000923"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEI8467841.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31865..32920)
                     /locus_tag="SLE23_000924"
     CDS             complement(31865..32920)
                     /locus_tag="SLE23_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEI8467842.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="SLE23_000925"
     CDS             complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="SLE23_000925"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEI8467843.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="SLE23_000926"
     CDS             complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="SLE23_000926"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEI8467844.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLAHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="SLE23_000927"
     CDS             complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="SLE23_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEI8467845.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="SLE23_000928"
     CDS             complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="SLE23_000928"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEI8467846.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="SLE23_000929"
     CDS             complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="SLE23_000929"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEI8467847.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40682..42241
                     /locus_tag="SLE23_000930"
     CDS             40682..42241
                     /locus_tag="SLE23_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEI8467848.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(42352..44283)
                     /locus_tag="SLE23_000931"
     CDS             complement(42352..44283)
                     /locus_tag="SLE23_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8467849.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="SLE23_000932"
     CDS             complement(44301..45215)
                     /gene="pfkB"
                     /locus_tag="SLE23_000932"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEI8467850.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(45212..45964)
                     /locus_tag="SLE23_000933"
     CDS             complement(45212..45964)
                     /locus_tag="SLE23_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8467851.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(46123..46332)
                     /locus_tag="SLE23_000934"
     CDS             complement(46123..46332)
                     /locus_tag="SLE23_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467852.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(46343..47671)
                     /locus_tag="SLE23_000935"
     CDS             complement(46343..47671)
                     /locus_tag="SLE23_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467853.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47807..47962
                     /locus_tag="SLE23_000936"
     CDS             47807..47962
                     /locus_tag="SLE23_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467854.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(48036..48623)
                     /locus_tag="SLE23_000937"
     CDS             complement(48036..48623)
                     /locus_tag="SLE23_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEI8467855.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48706..49956)
                     /gene="clpX"
                     /locus_tag="SLE23_000938"
     CDS             complement(48706..49956)
                     /gene="clpX"
                     /locus_tag="SLE23_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEI8467856.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(50203..51492)
                     /locus_tag="SLE23_000939"
     CDS             complement(50203..51492)
                     /locus_tag="SLE23_000939"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEI8467857.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51646..52578)
                     /locus_tag="SLE23_000940"
     CDS             complement(51646..52578)
                     /locus_tag="SLE23_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467858.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52735..53394)
                     /locus_tag="SLE23_000941"
     CDS             complement(52735..53394)
                     /locus_tag="SLE23_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEI8467859.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(53397..54422)
                     /gene="sppA"
                     /locus_tag="SLE23_000942"
     CDS             complement(53397..54422)
                     /gene="sppA"
                     /locus_tag="SLE23_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HEI8467860.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54435..54725)
                     /locus_tag="SLE23_000943"
     CDS             complement(54435..54725)
                     /locus_tag="SLE23_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467861.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            55134..56939
                     /gene="glmS"
                     /locus_tag="SLE23_000944"
     CDS             55134..56939
                     /gene="glmS"
                     /locus_tag="SLE23_000944"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEI8467862.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(57011..58366)
                     /locus_tag="SLE23_000945"
     CDS             complement(57011..58366)
                     /locus_tag="SLE23_000945"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEI8467863.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(58390..59559)
                     /locus_tag="SLE23_000946"
     CDS             complement(58390..59559)
                     /locus_tag="SLE23_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467864.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59556..60443)
                     /locus_tag="SLE23_000947"
     CDS             complement(59556..60443)
                     /locus_tag="SLE23_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEI8467865.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60632..64324)
                     /gene="nifJ"
                     /locus_tag="SLE23_000948"
     CDS             complement(60632..64324)
                     /gene="nifJ"
                     /locus_tag="SLE23_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HEI8467866.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64523..65044
                     /locus_tag="SLE23_000949"
     CDS             64523..65044
                     /locus_tag="SLE23_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEI8467867.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT        18251 a        14203 c        11673 g        21435 t
ORIGIN      
        1 aaaaacaaag tctttatttc tattatttac ctgtaaccgc aaagtagttg ccatcgggat
       61 cagcaaagtt aaagacatat tcttctccaa gctgtaccat atcacctaat gtgactgatt
      121 gcgtctgcat ttttttatat agtccaaaga tatctttact gtaaaacatc aaagatgggg
      181 cactagtagc tgtgccaggt gaatgggact caacaaatgc tcgatcatat aacagaaatg
      241 aggtttgact gtcctcaact cctacttcaa ttataagcgt cccatccatt tcttgacgat
      301 ctttttccgc aaagccaact gctctccaaa acgttgcatt tttttctaca tcgtccacat
      361 aaagcatgat ttttatttca ttcgtaaaca tctgtttcct cctaaacgat ctgttctaac
      421 attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag ctctcaacag
      481 aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt ttttgttatt
      541 tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata aaaaaagagg
      601 tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca actcctcggt
      661 cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct ctttgtgact
      721 cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
      781 cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg ctgttcttat
      841 tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag aagtagcttc
      901 tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa acttcttctt
      961 atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt cacatcgatc
     1021 actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc acttgtcacg
     1081 ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc gattaatggt
     1141 tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc taaaacgatc
     1201 agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact gattgttaca
     1261 attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc tgctggtgcg
     1321 acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc aatagacaaa
     1381 ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt tgtctgagtc
     1441 tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa gctcaatacc
     1501 ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa aatcagtgag
     1561 tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt acctaaattg
     1621 acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa tactccataa
     1681 ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag actgtcgact
     1741 aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag ataagcgatt
     1801 ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact acctgctaaa
     1861 tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga taagttttca
     1921 actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc tccttgtgtg
     1981 aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa tgctgcaata
     2041 gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag cttttcagaa
     2101 actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat aactagcatt
     2161 tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga ttgagtaacg
     2221 actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat accaactcct
     2281 aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg atagaacaca
     2341 tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt catttttctc
     2401 ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga gaatgattct
     2461 tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac gatttttatc
     2521 gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg atagctttaa
     2581 tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa ttcaatttta
     2641 ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt acgatatcga
     2701 ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga ccttcaattt
     2761 tccgattgag gatatgattg atctgactca cacttccaga taaaacatat gtatcaaaca
     2821 ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag ttttcgatcg
     2881 tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg ttcggcaatc
     2941 tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc atataatttt
     3001 atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta ctttttaatg
     3061 atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc cgggatctca
     3121 cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt ccctgcttcg
     3181 atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg aaaagtatcg
     3241 atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc gatccctact
     3301 acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt tgattctgtc
     3361 aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc cagtacttgt
     3421 ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg gtgaaataat
     3481 tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt agaatacttt
     3541 ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt tagtgcttgc
     3601 catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa gtcccatata
     3661 taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct ctcactttta
     3721 gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc tgccaatgta
     3781 tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc aggaacatct
     3841 tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag taaatcttgc
     3901 cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg attcactgtc
     3961 atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata tctgcggtca
     4021 aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca tgtttttact
     4081 tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag atccccataa
     4141 tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc catttcttct
     4201 agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac ggcatcgaat
     4261 tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt tcctttttct
     4321 gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc gctttcgcca
     4381 tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg aattttatac
     4441 cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc tgcttttgat
     4501 gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact tgctttttgt
     4561 tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa cgttgattct
     4621 catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat ccgaaaaaga
     4681 cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa ctaaagacaa
     4741 gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt ccctgcataa
     4801 gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc atcatattat
     4861 ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa gccttaattg
     4921 gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc aatcacaatc
     4981 actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg aagaaacagc
     5041 ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat caattgagga
     5101 aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt cgttttgatc
     5161 agattccgtt ttttactgat cactttttaa aagcttttta gaatcttttg ctgacgtcta
     5221 aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg cagttctgct
     5281 gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg aaacagttca
     5341 accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac tggtaattcc
     5401 aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata gatttctcct
     5461 aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt attttcctgc
     5521 aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac aactaaaaaa
     5581 ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa aagaaagtct
     5641 gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac gagaaaaata
     5701 caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat ttcctcttca
     5761 aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa gttcttgcat
     5821 tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt ctacatcaat
     5881 actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa tcgcatccat
     5941 tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt ctggcgaaat
     6001 gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat gtaagatcgt
     6061 tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca ttcctccgtc
     6121 aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt gctttccccc
     6181 aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt ataaatatat
     6241 cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac accaaacccg
     6301 tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat tgataaaata
     6361 aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat tgctaaaaag
     6421 atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat caagaaataa
     6481 taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc gccgatccca
     6541 attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa ttcttcaacc
     6601 tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc cattaaaaag
     6661 ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc taaatgctgt
     6721 cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc aatagtcgtt
     6781 atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa actaatgata
     6841 ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc catggtaacg
     6901 atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc cccaaaatca
     6961 tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg tcattttcat
     7021 ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata aatggaacag
     7081 ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat tcggaactgg
     7141 tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga taataggata
     7201 gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg acgctgacga
     7261 tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact tgttgtccca
     7321 aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat cccaaactga
     7381 ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct ccgacttcca
     7441 tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg attgccgcac
     7501 caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac gttaaaatga
     7561 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
     7621 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
     7681 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
     7741 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
     7801 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
     7861 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
     7921 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
     7981 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
     8041 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
     8101 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
     8161 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
     8221 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
     8281 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
     8341 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
     8401 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
     8461 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
     8521 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     8581 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     8641 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     8701 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     8761 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     8821 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     8881 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     8941 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     9001 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     9061 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     9121 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     9181 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     9241 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     9301 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     9361 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     9421 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     9481 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     9541 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     9601 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     9661 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     9721 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     9781 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     9841 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     9901 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     9961 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
    10021 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
    10081 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
    10141 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
    10201 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
    10261 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
    10321 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
    10381 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
    10441 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
    10501 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
    10561 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
    10621 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
    10681 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
    10741 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
    10801 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
    10861 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
    10921 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
    10981 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
    11041 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
    11101 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
    11161 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
    11221 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
    11281 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
    11341 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
    11401 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
    11461 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
    11521 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
    11581 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
    11641 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
    11701 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
    11761 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
    11821 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
    11881 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
    11941 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
    12001 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
    12061 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
    12121 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
    12181 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
    12241 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
    12301 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
    12361 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
    12421 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
    12481 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
    12541 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
    12601 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
    12661 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
    12721 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
    12781 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
    12841 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
    12901 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
    12961 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
    13021 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
    13081 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
    13141 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
    13201 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
    13261 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
    13321 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
    13381 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
    13441 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
    13501 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
    13561 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
    13621 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
    13681 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
    13741 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
    13801 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
    13861 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
    13921 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
    13981 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
    14041 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
    14101 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
    14161 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
    14221 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
    14281 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
    14341 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
    14401 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
    14461 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
    14521 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
    14581 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
    14641 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
    14701 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
    14761 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
    14821 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
    14881 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
    14941 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
    15001 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
    15061 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
    15121 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
    15181 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
    15241 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
    15301 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
    15361 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
    15421 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
    15481 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
    15541 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
    15601 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
    15661 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
    15721 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
    15781 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
    15841 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
    15901 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
    15961 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
    16021 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
    16081 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
    16141 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
    16201 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
    16261 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
    16321 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
    16381 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
    16441 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
    16501 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
    16561 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
    16621 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
    16681 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
    16741 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
    16801 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
    16861 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
    16921 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
    16981 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
    17041 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg cagcgatggg
    17101 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
    17161 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
    17221 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
    17281 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
    17341 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
    17401 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
    17461 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
    17521 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
    17581 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
    17641 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
    17701 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
    17761 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
    17821 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
    17881 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
    17941 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
    18001 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
    18061 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
    18121 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
    18181 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
    18241 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
    18301 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
    18361 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
    18421 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
    18481 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
    18541 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
    18601 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
    18661 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
    18721 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
    18781 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
    18841 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
    18901 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
    18961 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat ttttttggca
    19021 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
    19081 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
    19141 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
    19201 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
    19261 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
    19321 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
    19381 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
    19441 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
    19501 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
    19561 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
    19621 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
    19681 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
    19741 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
    19801 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
    19861 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
    19921 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
    19981 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
    20041 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
    20101 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
    20161 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
    20221 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
    20281 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
    20341 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
    20401 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
    20461 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
    20521 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
    20581 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
    20641 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
    20701 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
    20761 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
    20821 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
    20881 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
    20941 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
    21001 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
    21061 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
    21121 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
    21181 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    21241 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    21301 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    21361 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    21421 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    21481 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    21541 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    21601 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    21661 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    21721 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    21781 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    21841 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    21901 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    21961 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    22021 ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac
    22081 tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta
    22141 tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta
    22201 aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg
    22261 gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc
    22321 cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc
    22381 ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa
    22441 tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc
    22501 caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg
    22561 gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc
    22621 agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt
    22681 cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata
    22741 ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg
    22801 ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc
    22861 attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac
    22921 cagtacttct atttctttga cttttggata caatccggct cctaaccaca taccggattt
    22981 aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt
    23041 ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata
    23101 agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat
    23161 tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa taatatctta
    23221 cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt
    23281 catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga
    23341 ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca
    23401 tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt
    23461 catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga
    23521 tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg
    23581 gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat
    23641 cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa
    23701 tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct
    23761 gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc
    23821 atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata
    23881 aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat
    23941 tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg
    24001 gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga
    24061 ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc
    24121 ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc
    24181 acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt
    24241 gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt
    24301 tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta
    24361 agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat
    24421 ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc
    24481 ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt
    24541 cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca
    24601 ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta
    24661 atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt
    24721 ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg
    24781 gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa
    24841 cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta
    24901 ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg
    24961 atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt
    25021 ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt
    25081 ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc
    25141 ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg
    25201 ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg
    25261 agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa
    25321 catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg
    25381 gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct tttcttcttc
    25441 aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc
    25501 tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc
    25561 tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac
    25621 tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa
    25681 ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg
    25741 ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg
    25801 gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc
    25861 aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa
    25921 ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg
    25981 cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc
    26041 aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc
    26101 atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct
    26161 ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc
    26221 aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac
    26281 cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc
    26341 atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg
    26401 tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc
    26461 gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata
    26521 aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc
    26581 aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc
    26641 agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat
    26701 gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag
    26761 tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc
    26821 agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat
    26881 caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc
    26941 tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt
    27001 cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc
    27061 ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa
    27121 tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa
    27181 ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt
    27241 tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct
    27301 atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa
    27361 ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag
    27421 tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca
    27481 gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg
    27541 atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag
    27601 agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc
    27661 tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg
    27721 aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt
    27781 gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac
    27841 atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca
    27901 gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga
    27961 atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct
    28021 ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa
    28081 tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat
    28141 ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca
    28201 attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta
    28261 gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa
    28321 atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt
    28381 atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt
    28441 atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata
    28501 ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt
    28561 ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat
    28621 ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg
    28681 attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt
    28741 tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt
    28801 tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa
    28861 tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat
    28921 ggttcctttc agactatctt ttggaagtag atgtttgatt ttcatttgtt tagcatacgc
    28981 atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc
    29041 aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt
    29101 gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata
    29161 attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac
    29221 acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg
    29281 ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact tggactcata
    29341 cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt ttttatcagt
    29401 gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc tgggggaaag
    29461 ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga accatccgat
    29521 aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa gcattctgat
    29581 tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt ttccccaaac
    29641 ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa caaaacattt
    29701 tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc caaaggcaga
    29761 tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat ttcgccattt
    29821 ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct ctaaaagaac
    29881 aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat tttcttgagt
    29941 aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg aataataatt
    30001 tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa taaaaatctt
    30061 tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa tgacgttcat
    30121 tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc gccaaaataa
    30181 tgtagactaa ctaaaaagac taagaaacaa taacaaaagt taacacttct tagtctttct
    30241 ttagcacgtc tatttattaa agattttagg gccttttctc atgtttttac gatcattctt
    30301 aggtgtttcc atttgtttgg atcggcctcc accttgtttc tttttgatca attctttcat
    30361 tttttctttt tggtccattt ttattctcct ttaacgaatg aagcgactaa ttcgatatga
    30421 tgggtttgcg ggaaaagatc tacaggctga actttcttca cggcataacc tgcttctgca
    30481 aataacttag catctcttgc aaaagttgcc ggattacatg agatatagac gattcgttct
    30541 ggtgacattt cgattgctga ttcaataaaa tgatgatcta atccttttcg tggagggtca
    30601 actacgatca cagatggttt gatccctttt tcttgccatt ttttcataac tttttctgct
    30661 tttccgactt cataatgaac attttcgatt ttattattta aagcattgaa ctgtgcatct
    30721 tcaattgctt ctggaataac ttccatccca tacaccttat ccactctgtc tgctaaagac
    30781 aagccaatcg tacctattcc tgaataagcg tcgatcacaa tgtctttttt atctaactcg
    30841 gcaaactcga tggctgtttg gtacagatac tctgcttgtt gagtatttac ttgataaaat
    30901 gactttgctg agattcgata ggtttttcct aatagctgat cttcgatata gtctctgcca
    30961 tataaaactt tttctttgtc tcctaaaatc acatttgttt tttcttcatt gatattttgg
    31021 atgaccgaaa ccacttctgg caattcttca tgaatagctt cagcaatttc cttggattta
    31081 aagaattttt ctttacgagt aactaaaacg accatcattt catgggaata atgaccacga
    31141 cggataatga tgtgacgaag ctgtccttca tttttttctt cattatatcc tcgtacttgg
    31201 aaccgttgca agatatctct gactactttg attgcttgat cgatgacagg atcttggata
    31261 taaaaatctt cgatagggac tagatcatgg ctattctttt tgtaaaaacc ggtggctaac
    31321 tgtccatcga tacggcgaac agggatctgt gctttattac ggtagccgaa tggttctgcc
    31381 attccgaccg ttggaagtac aggaacttct ggcatcttag caatcttcgc cattacatgc
    31441 tctacttgtt tttgtttgaa gacaagctgt tgttcatact tcaaatgggc taaaggtgcg
    31501 atacctatgc gaagtaatgc attgttttct acaggctgac gatcaggtga ttgtgtaata
    31561 aatgtttcga cttttccata tccaaactta ttgcctgctt ttactactag tatttctact
    31621 tcttctccag ggagtgcatt ttcgataaat aatggataac catcgatttt tgctaccccc
    31681 attccttcat aactcaagtc gacgatttcg actgtatatc gttcgttttt ctttactatt
    31741 tgctgttctg tcatattttg ctcctttaag cctatttttc aatcctactg aactctacta
    31801 taaatcagct aattacacaa ctaaaaccgg cactgacctt actacgttca gcaccggctt
    31861 ttgattaatt cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg tcgatatctt
    31921 catccgttaa acgttcgact tcttttacga attctttgct gacaacctct aattcttctt
    31981 catctgtacc tgtgattgct tcatcaggaa tctgatcggt attggcaaag aactcaatgt
    32041 gttgatgaag attttggaaa tgcatcggtg cttccccgcc gtattcacca tctaagttga
    32101 tcattactgg tcgattgata tcatcttctg tttcaacgaa caaactgctt gttttggtat
    32161 agattattct tggatcatcg acatgtcgac cgccattcag catgagtgct gcaatatgca
    32221 agatctcaaa gatatttgct gtcttcacaa tgattaaaga aaacttccca tcatccaatt
    32281 tggcatctgg cgcgatctgt tcgaatcctc caacagagtt cgtcagccct aggaaaaaca
    32341 tcgaagcatt tccgatatat tccccttcat catacttcaa gcgcattttg attggcttta
    32401 ctcgagggag catctctgct cctttcgcaa gataagcaag ataaccaaaa atactcttta
    32461 gttctgatgg aacttcataa gtcaattctg tcaaatagcc acctgcagcg atattgatga
    32521 agtaactgtt atcagaaagg ccgatgtcca tttttacggt ttggtgtttt tttatcactt
    32581 ctgctgctgc tttaatatta tctctaggaa tttttaatgc tcgagcatag tcgttcgttg
    32641 taccagctgg gatgatggcc attttaggac ggtgttcaag cggagcgatt ccattaacca
    32701 cttcgttgat tgtgccatcg ccaccagctg ccactactag atcaaaacct agttctgcga
    32761 ctctacatgc ttcattcttg gctgaatctg gttctggtgt agttgcatag gcgctggctt
    32821 caaatcctgc ttcttctaat gcctgtagga tatccgccaa attttttttc aataattctt
    32881 ttcccgaggt ggggttataa attacgcgtg cttttttcat tttcagcctc tatcgtttcg
    32941 ctaattcatc tttaagtagc ttattcacga caccaggatt tgcttgtcct ttagttgctt
    33001 tcatgatttg accgactagg aagccaaccg cacgatcttt tccatttttg aaatcatcga
    33061 cagattgttg gttgttatcc aaaatttcat taatgattgg cagtagtttg ttcggatcag
    33121 ataattgcac ccaaccattt ttttcaacta cttcttgggc ttctccgcca tttgtgatca
    33181 attcacggaa gacttttttg gcgatttttg agctgatcgt tccatcggcg atcaaacgaa
    33241 tcattcctgc taagttctca ggtgtcaatt ttgtctcagc taattccagt ttctcactgt
    33301 tcaagtaagc agaaacttca cccatcaacc agttagatgc ttgcttggca tctgcaccat
    33361 tttccaaaac agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat accattgcgt
    33421 catactctgg aagtccaaac tcacggatat agcgttcgcg acgagaagct ggcatctcag
    33481 gcaaactagc ttttactttt tgaatccatt cgtcatcgat cacgaatttc gggatatcag
    33541 gctctgggaa gtaacgataa tcactagacc cttctttgac acgcatcaaa actgttttat
    33601 tcgttgtttc gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa agaagaactt
    33661 ttgcttgacg tttttcttca aaagctaaac cttttttcac gaaagataaa gagttcaagt
    33721 ttttcaattc tgctttcgta ccgaactctt cttgtccata agggcgaaga gaaatattgg
    33781 catcacagcg catagagcct tcttccattt tcacatcgct gacttctgta aattggataa
    33841 ttgatcgcaa tgcttctaga taagcgtatg cttcttctgg tgaacgcata tcagcttcag
    33901 aaacgatttc gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa taaccgccaa
    33961 taccatgcat gttttttcca gcatcttctt ctaaatggac acgttcgatc cggatttttt
    34021 tctttttacc ttctacttcg atttcgatcc atccgtcatg accgattggt tgatcaaatt
    34081 gggaaatttg atatgctttt ggattatctg ggtaaaagta atttttccgg tcaaaatgag
    34141 tatctttaga gatttcacag tttaatgcca aagctgcttt catcccgaat tccagcgcag
    34201 ctttattcat tactggcagc acgcctggat aaccccagtc gatcacgttt gtattgctgt
    34261 ttggttctgc accaaaatga gctggcgctg gagagaaaat ttttgagttg gtttttaact
    34321 cgacgtggac ttctagtcca atgactgttt caaaattcat tcgtctttcc ctcctaaaat
    34381 agctggttgt tgtttatgga attctgttgc ttgttcaaac gcatatgccg cttgatacat
    34441 cgttttttca tcaaaataat taccgatgat ctgcaatcca actggtaatc cttctgataa
    34501 acctgccggt acagacatac ctggaagtcc agccaagttg acagggatcg ttaagatgtc
    34561 actcatgtac attgtgattg gatcgttaat gttctcaccg attccgaatg caactgttgg
    34621 tgaagatggc ccgatgatca agtcataatc tgcaaagact ttttcaaaat ctcgtttgat
    34681 caatgtacgg acttgtcctg cttttttgaa gtaagcgtca taataacccg cgcttaagga
    34741 gaatgtacct aacatgatac ggcgttttac ttcttcaccg aatccttctg aacgtgagtt
    34801 gacatataca tcatctaatg atttcacatt ttcagagcga taaccgtagc ggataccatc
    34861 gaatcgttgc aaattggaac ttgcttctga tgaggcaatg atataataaa cagccacacc
    34921 gtattttgaa tgagccaagc tgacttcttc cacaacagca cctaatgaac ggaatgtttc
    34981 tgctgctttc aatacagctt cttttacgcc aggggccaca ccttcgccta agtattcttt
    35041 aggtaaagca atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa aatcaggaac
    35101 tgaaacgcct gaagaagtac cgtctttttc gtcataaccg ctgatagctg tcaatgctaa
    35161 tgcattatct ttcaccgtac gggtcattgg tccgatttgg tcaagagatg aagcaaaggc
    35221 aatcaaacca aaacgtgaga cacggccata agtaggtttc atccctacga tgccgttaaa
    35281 agctgctggt tggcggatac ttcccccagt atcactacct aaagaaactg gaatttgtcc
    35341 agctgcaact gctgctgcag aaccaccaga agagccacca ggtacttttg ttgggtccca
    35401 agcatttttt gttttcttga aataagaagt ttctgtactt ccacccatag caaattcatc
    35461 catgtttagc ttaccaacag ggatcatatc tgcttgatag attttatcca tgaccgttgc
    35521 atcataaatt ggttcaaaat tgtaaaggat cttagatgca gcggttgtca agatatcttt
    35581 tgttacgata ttatccttga taccaattgg aataccagca aggacgttgc tttcatcaat
    35641 ccctttttca tctaaagctt ttgcctgttc caatgctttt tcttcgttca atgtaatgaa
    35701 tgcctcgacc tcaggctctg tttctttgat tcgttcaaat gttgtttttg tcaaatcttg
    35761 tacagtgatt tctttcgata caagcatatg atgcagttct tctagagaac gattgtgtaa
    35821 ttctgtcatt atgcgccagc ctccccatta tcgatgattg cgggtacttt gataaagccg
    35881 tcttctgttt ccggcacatt tttcaataat tcatcgcggt tccatccagc ttgcgcccga
    35941 tcttgtcgca tcacgtttac tgtttcaacc acattcgacg taaatggaac accttccgta
    36001 tctacttctt ccagcatttc aaccatatcg atgattttac ctaattggtc ggtaaaactt
    36061 gcaagttctt catctgcgaa cgcaagtttt gctaatttgg caacgtgttt cacttgttct
    36121 tcactaatcg ccatactacc ccttctttct aaacgagtta aaaactttgc tctctatttt
    36181 aacacaagag tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa actcattttt
    36241 cattcttcta ctgagcgact tttagccaat gcatctgcca tttgatcttc tgtccaaact
    36301 tcgattccta attcttgtgc tttggtcagc ttgctgccag catcttctcc tgctaccacg
    36361 atatccgttt ttttcgatac gctaccagtc actttcccgc caagattttc gatcgtctct
    36421 tttgcttctt cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt tttttcttta
    36481 aaaggagact cgacttcttg caattgggca tttcgaagcc ctttgtattc gaaattgacg
    36541 cctgcttgtt ttaattcatt catcaattca tggacttctt cgttactgaa ataagtgact
    36601 acactgtcgg caatgatatc accgatcgta tcaagcgcaa taatcgactc atagtcactt
    36661 ttactcaatg tttctagatc accgaaatgt tctgctaaaa tttttgctgc tttcgctccg
    36721 acatgtcgga ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt gctgttgtcg
    36781 attgctgtca aaatattatt tgctgatttt tcttttattt tgtccaacgt caataactct
    36841 tcttctgtca atttgtaaag atcagcaaca tctgctacta gttttttatc atacatctgt
    36901 tctagtacgc gcggccccaa cccatcgata ttcatcgcat ttcttgaaac aaagtggttc
    36961 aaaccttctt tcatttgagc agggcattta ggattgatgc accgtaaggc tacttcttca
    37021 tccaaatgga caagttcact tccacaaact ggacaatgtg taggcaattg gtattcttcg
    37081 ctgtctttag gtcgtttatc taacacgact tgcgaaactt ctgggatgat gtctcccgct
    37141 ttataaatca gaactgtatc tttcaagcgg atatccttca acttaatata atcaccgtta
    37201 tgcaggctgg cacggcttac tgtcgttcct gctactcgga ctggtgtcat gatagctgtt
    37261 ggcgttacta cccctgttcg accgactgtc cattcgatgt tttcgattag cgtttcaact
    37321 tcttctggcg gaaacttgta agctgctgcc catctcggtg ctttgatagt aaaaccaagt
    37381 tgatcttgta gcgagaattc attcactttg atgacgattc catcgatttc atagggcaaa
    37441 tccacacgtt tgtcatgata ttcttcaatg tatgaccaca cttcatcaat cgaatgacat
    37501 agacgttttt cccgattcgt gtggaatcca attttttcta gctcttctag cgcatcatac
    37561 tgggtttttg cttgcatagg accgaaatca gctactgtgt ataaaaaagt gtccagattt
    37621 cttttcgctg tgattttaga atctaactga cgcaaagaac cagctgcggc gttccgagga
    37681 ttcgcaaaga tatcttttcc ctctgcttct ctgtcttggt tcaattggac aaatgaccgt
    37741 tttggcatga aacattcgcc tcttacttcg atgttcattg gttcttttaa tttgattggg
    37801 accgaccgga cagtttttag gttttcagtg atgttttctc ctacagttcc atccccgcga
    37861 gtcgcacctc tcacgaaatt tccatcttca taacgcaaag aaacggaaag tccatctatt
    37921 tttagttcac agcaatagtc aactacacgt cccactgctt tttgtacacg ttgatcaaaa
    37981 gctatcagct cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat atcatgagtg
    38041 actttttcaa aaccttctaa tacttttccg cctactcgtt gagtgggaga atcagacgtg
    38101 atcaaatcag gatattgttc ctcgattgct actaattctg cgtattcttt atcataaaca
    38161 tagtcttcca ctgttggttt atcttctacg tagtattcgc gagaccattg gttcagtctt
    38221 gtacgaagtt cttctgctcg tttagcagct tcgtcaatcg tcatttcatg ttccatcatt
    38281 taccctccac tactaagctt tttcaattgg cgcaaaggca gccaaaagac gttttactcc
    38341 ttgacttggg aaagccacat ctagttctag atccttcgac gtcccgctta ctcggacgac
    38401 tgttcctaga ccccattttt tgtgtttgac tttatctcca ggtttccagc tgttattttc
    38461 ccctccagta gcacttttag agggaacaac cgctgtctct ggctgtttat agctatatgc
    38521 tgttttttta gcgaatacag gcgttttttt aggcgtagga cgcatgcctt cgatttccag
    38581 taactcctga tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg tccgtccata
    38641 taatgttctg gagaaagcat ttgttaaata caacgcttct tctgctcgcg tgatccccac
    38701 atatgcgaga cggcgttctt cctccagttc gctttcttcc atcaatgctc gagataaagg
    38761 aaaaaccccc tcttctagac caatcaggaa tacaactgga aattctaatc ctttggctgc
    38821 atgcaaagtc atcaatgtca cttgggaagc atcttcttct aaattgtcaa tgtcggaaac
    38881 aagtgccaga tcatttaaga agaccgttag tttttcttct ggtgcatcag cgtcttcttc
    38941 attttgctgt tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt cctccaagtt
    39001 ttcgatgcgt gcttgtgctt ctaatgtatt ttggattttt aagtcttcta gatatccgct
    39061 acgatccaaa acctctttcg tcaattctgt cactgtcaag tatgggatca tctgagtgac
    39121 ttcttggatc atctctccaa atgcacctaa ttgctgtcct gcttttccac cgatatttgc
    39181 cagatccaca ttttgcgctg cttcaagcag tggccattca tgaagagaag caaaactgcg
    39241 tagtttttcg atagatcctg gtccgatgcc tcgtttgggc gaattaacga tacgctcaaa
    39301 actgattgaa tcttgaggat ttaccagcac attcaaatac gctaaaatat ctttgatttc
    39361 tttacgatcg tagaacttgt gccctccaac cattttataa ggaatatttg ctttcaacag
    39421 agtttcttcc attacacgag attgtgcgtt cgtccggtac aagatggcaa agtcgccgta
    39481 attccgatga ttgcttcgaa tctcttcttg catccggtct acgataaaac gggtttcgtc
    39541 tcgttcatta tctgcacggt agtaagtgat cttgtttcct tctttgtttt ctgtccacaa
    39601 gttttttggt tttcgattgc tattgttttc aatgacttgg tttgctgcgc taaggatgtt
    39661 tttcgtggag cgatagtttt gttctagcaa aattactgca gcatctggat aatctttttc
    39721 aaaatccaag atgttctgca tatctgcacc gcgccagccg taaatacttt gatctgcatc
    39781 tcccacgacg cacaggttcc taaatctacc tgccaataaa ttgactagcg tatactgtgc
    39841 gtgatttgta tcttggtact catctacatg aatataatgg aatttgtttt gataatacgt
    39901 gagtgaatca ggatgttctt caaataatcg aatcgtattc atgatcaggt cgtcaaagtc
    39961 catacattga ttatattgaa gctctttttg gtaagcagca taacattttg ccgcaatctc
    40021 ttcgtaataa ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc tgttttttgc
    40081 ttgagagatt gttcctaata tacttcgagg atcatatttt ttcggatcaa tgttcagttc
    40141 ttttagtatc cgtttcatca aggtcagctg ttcagaagaa tcgatgattg taaagttccg
    40201 gttatacccg ataaaatcaa catctcttct taaaatacgc acacacatcg agtgaaaagt
    40261 cgatacccag acatcttcgc ctccagatgc gagaatcgca ttgacacgtt ctttcatttc
    40321 ttttgcagcc ttattggtaa aagtaatcgc taggatgttc caaggattga cttctttttc
    40381 ctcaatcaaa taggcaatgc ggtgtgtcag cactctcgtc tttccacttc ctgcacctgc
    40441 cattagcagt aatggtccgt cagtgtgaag aacagcttct ttctgacggg ggttcatccc
    40501 gtttaataat tcagctttgg atgacattaa caacatcctt tcttttatca atcttgttaa
    40561 ttatagcatt ttcttggctt tcattaaact agctagttca aaatcatttg tttcttttta
    40621 tggatttttc cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc gaggcgtttg
    40681 aatggaaaaa aaaggaaaaa tcaagaaatt agataagact cagatatatt ttattctaaa
    40741 aggaatattt gttggactgc tgacaggaat cgtcgttagc ctgtttcgat tatctatcga
    40801 aaagctaagc gatttagttc gaagtatcta tgaaatgagt cgggaacagc cgatttactt
    40861 aattggccta gctatttgct gcatccttgc agcatttttc gtgggttatc tggtcaaaaa
    40921 tgaaccggat atcaagggaa gcgggattcc acaagtagtg ggacagcttc gcggggaatt
    40981 atcaatgaac tggttctctg ttttatggaa aaagttcatt ggcggtgtac tttcagttgg
    41041 tgcgggcctt tttctaggta gagaaggacc ttctatacag cttggcgcat ccattggaca
    41101 aggagctgga caattgtttc ggagtccatc ttcagaagaa aagattttaa tttctagcgg
    41161 tgcaagtagc ggacttgcag cagcattcaa tgctcctatc gcaggattac tctttgtttt
    41221 agaagaaatc catcactcct tttctccact tgtttggctg acatcatttg cttcagcaat
    41281 cactgctaac ttcgtctctc tttacttttt cggcttgaga cctgttttat atctaggtga
    41341 ccttccttct ttgccgttga aatattatgg ttccttagtg atcttaggag tacttctagg
    41401 catcttaggt tttatttatc agaatgtctt gctggctttg ccaaaatttt acaaccgatt
    41461 gcctttacca gcttattttc acgggttcgt tcctttcttg ctgattttgc caattggtta
    41521 tttatggcct agtactctag gcggaggcaa tcaaatcgtt ttagcttttg gacatgcttc
    41581 cttgccaatc attatgatta tcggtttgtt tgttcttcga ttcgtttttt ccatgatttc
    41641 ttacggtggg ggtcttccag gggggatttt ccttccgata ttgacattgg gggctttaat
    41701 cggtagcttt tatggaaaca ttatggttga tttcgggatg gatccaatct acatcaagga
    41761 ttttgtcgtt attgccatgg ctggttattt cacagcgatt ggaaaagcac cgctgacagc
    41821 aattatttta gtgacagaaa tggttggctc tcttaatcat ctgatgcctt taggattggc
    41881 tgctcttgtt gcttatatcg tcaatgacct tctcggcggt aatccaattt acgaatcatt
    41941 attggaacgt ctacttggaa atactcagac cgcctcacta aaaggtgcaa ggacaacttt
    42001 tgattttcca gtaacggcag agagttcttt agacggatta atggtacgag acttcaattg
    42061 gcctaaaaat atgctgctaa tctctatacg cagaggaaat caggaaatct tgactcacgg
    42121 tgatacgatc atgaatgtag gagatatttt ggttatcttg actgatgaag caaacttgcc
    42181 aagaatcaag caggaaatcg aggctaaatc ttctatcaca aatttgaagc aatcatttta
    42241 acgaacatgg aaaaactatt ttacaacaac tattcatcta cactacttga ttctatatga
    42301 ttctataaaa aaagaagagg ctgggaaaac ccagcctctt cttttttatt tctatgcttc
    42361 tgctactgca ggagcttttc tcaataaacc ataaatcaca ccagatacga ctgctccgat
    42421 agcaataaac accaaataca tgaccgggtg actcagtaag aatacaacga aaatcccgcc
    42481 gtgaggagcc agtaatttga ttccgaaagc tccgactaat ccgccagtta aagcagaacc
    42541 aataataaaa cttggaatgg cacgaatcgg gtcagctgct gcaaatggaa tcgatccttc
    42601 cgtgacaaac gatagtccca tcacgatgtt cgtcaaacca gcatcttgat ctgttttgct
    42661 gaatttattc ttaaacaaac gtgtagcaac gaaaattgcc aatggaggta ccattcctcc
    42721 agccataaca gaagccatca cgacacttcc gccagttgca acagtcgtag ctaaagttgc
    42781 tgtaccaaac acataagcgg ctttgttgat tggaccgcct aaatctgccg ccatcattcc
    42841 agctaataat gcaccaagta aagcagcatt cgaaccactc atacttgtca agaaaccgtt
    42901 caatgcatca ttgattgctt tcatagggac attgaccagc aacatcaaga aaccagtaat
    42961 cagtaagcca aacactggat aaaagaggat cgttttaatt ccatccaatg attttggtaa
    43021 gttcttgaat aatttacgta aaaatacgat gacataacca gctaagaatc caccaatcag
    43081 tgcacctaag aatcctgcac cgcctgtatt agctaatgca ccagcagcaa atccaacgat
    43141 caaaccaggg cggtcaccga tacttgaagc aataaatcct gctaataccg gcagcatgaa
    43201 accaaatgca gcttgtccga tttggttgaa ccagctagca gcttgattgt aattccctag
    43261 atttgataat tgatcatgtg gcacgccaat aaattggtcg atcatgaaag aaagcgcaat
    43321 agcgattcct ccaccaataa cgaaaggtaa catgtgtgat acgccgttca tcaaatcttt
    43381 gtaaattctt tgtccgatag taccatccgc atttccttct tctgaactgc tttcttttcc
    43441 atcaccatgg aatactggtg cagtaccact aagggctaga ttgatcaact cttctggttt
    43501 acggatacca tcactgacag gacgattgat cagttctttt ccgtcaaagc gattcatctc
    43561 tacttttttg tctgctgcaa cgattacacc ttctgcacgg gcgatgtctt cagcagtcaa
    43621 tcggtttttg attccttctg aaccgttcgt ttcgactttg atctccacac ccatttcttt
    43681 cgcttttttc ttcaaagcat cttctgccat gtaagtgtga gcgatccctg ttggacaagc
    43741 tgtaacggca acaacgaatt ttctttctgg atgagcagaa gcttctgcag cttgtgtttc
    43801 ttgttctgct ttttcttctg cttctttttg ctcttcagct gtttggaaca agtcttggac
    43861 ttcttctggt gtatttgctt cttttaattt tcctacgaaa tctgcatcaa tcagcaatcg
    43921 agatagtgct gctaatgctt gcaaatgtgt gtcgtttgcg ccttctggag ctgcgatcat
    43981 gaaaaacaga taagttggct gtccgtctaa ggcttcataa tctactcctt tttggctttt
    44041 tgcgaataaa actgttgctt ctttaactgc actgtttttc gcgtgaggca tggcgattcc
    44101 atcaccaaga cctgtagaag tttgtgcttc gcgggctaga attccttctt tatatgtttc
    44161 gatatcggaa atccggccgg catcaaacat tttttggacc atttcatcga ttgcgccttt
    44221 tttatcagtc gcttgcaaat ccatgatcat cgcttctttg accattaaat ccttgatatt
    44281 catgattatc ctccttgaaa ctaatcaatt tttgtgattt caacttctgg cagcaactca
    44341 tcaatcaatt cgcgagctgc caagtcatca gaaaaagctg ttgcgcttcc gcaagcaact
    44401 ccccatttaa aggcttcgat tggatctttc gtacggctgt aagccccaat aaagccagca
    44461 atcattgaat cccctgcacc tactgaattt ttcaatgggc gaactaatac attcgtttta
    44521 taagttcctt gttccgtgaa gagcaaagca ccgtctccag ccattgagat cagcacattc
    44581 tgtgcccctt cagctagtaa ttttttccca tacggaatga tttcttctac agattggaag
    44641 gttgtgttgt aaagctcagc taattcgtga ttgtttggtt tgatcaacaa cggtttctta
    44701 acaagtgcat tttttaggtc atcacctgtt gtatcaatca cgaaatctgc acctttttct
    44761 cgaatgatat caatcagttc ttgataaaat ccttttcgca ggctagctgg cgcgcttcct
    44821 gacaatacga cgatatctcc ttgtcctact gttcctaatg cttgcttcaa ctcatcgatt
    44881 tcttcatctg aaatagatgg gcctaagcca ttgatctcag tttcagtgtc tgattttagt
    44941 ttgatattga ttcttgtatc ttcttttacg gttgtgaaca aagactggat ttgttctttt
    45001 tcaagccact tcgaaataaa ttcgccagtg aaccctccta aaaaccctag tgctgtagat
    45061 tgagaatcga tccgtttcaa aatacgggaa acattgatcc cttttcctcc aggtaacttg
    45121 aagtcttcct tcattcggtt caaatcgcct agttttaacc catctacgcg tacgatataa
    45181 tcaattgatg gattaagtgt tactgtgtaa atcattgtat tgcctcctta attgttgtct
    45241 tttcacggaa ttcattaacg aattctaatg gacaacgctc ggttatgatc gtggctgctt
    45301 ccaaaggtgc aacagaggtg aaggacaact ggttgaattt ggtatgatca atcaatacaa
    45361 atgtctcttc ggaatttttc atggctaaac gtttaacagc tgcctcttct ggatccggag
    45421 tcgtgaatcc ttgttcaaga tgggcaccgt tcattcccat aaatgcttta ttaaaatgaa
    45481 aattttttag ttgttctatc gcattagatc ctaaaacagc attagttgcc agctttatcg
    45541 ttccacctaa aataatggta gcaagctcca aatcaactaa atttgccgca tgttgaacgg
    45601 aatttgtcac tactgtgatc tgttttcctt gcagaaaagg aatcatttct aacgtagtag
    45661 agccagcgtc taaataaatg acatcttcgt cattaatggt ttcagctgcc gatttggcga
    45721 tttgctgttt ttcgtgaacg tttttgagtg atttttcact catattctgc tcaaaattca
    45781 ataattgctc tttcttagct ccgccatgaa ctctttctag aaacccacta ttctccagct
    45841 cttgtaaatc acgtcttatc gttgattcag aagcattcaa aaggtttaca agatcttgtg
    45901 atttcacgat tttctgctgt tcaagcaagt ctaggatttt ttgtctgcgt tcctctgtaa
    45961 gcattttcac gatcacctca atacaaataa tagcatattt tttttctact agcaatataa
    46021 atcagtcaaa aacgttcata aaaattataa atcagtcaaa aaaaaataaa aaaccagtca
    46081 gaaagactgg ttttttattt ttttgtctat catcaagccg ttttatcgtt ttttattttc
    46141 gcttcttgtt tttttcatat aaacagaagc aggttttctt tccttatgaa gaagataata
    46201 ataaagtccc atcccgccaa acatgaccaa aaaaccgatg actgatcgaa taggaaaatt
    46261 aggaacaaaa aagagacaga cggataataa tgatgccgga accattattc gataatagag
    46321 ttgtttatcc attttcttca cctcatattt tttgtaaagt aatcaattgt tctaattctc
    46381 ggtaatctaa aaattgcaca cgcagatgct gctcaccttt cttgacatcg aattggatac
    46441 ttcgccgctt tttctttatt cgtttgaagg taacatcaga gagtctatgt ttgatttcct
    46501 ttaacggtaa ttctgacagg gattctgaag gaacatagat tcttaaggat aaaagatact
    46561 cttgatattt ttcatctgtt acctctactt ctagatattc cctaatataa taacaataag
    46621 cttcgattcc attatccaaa gcaacagtcg gatcgataac tttatagcac atcatgcgtg
    46681 atcgattctc gtcaacccaa ggaaaatacg cctgagcatt tagtgttccg cgaacacgcc
    46741 tttctttata atctccttgt tggatatcat aactttttgt tacaaaaaat gaagcattct
    46801 ttttaggaac aggttgcatt tgtgcattct gatactggac agattggatc gtatggtcag
    46861 tgtaaatgta ttcaacgaat ggcggtttca ataaaccgac accattgtcc caagcaagat
    46921 gatcaaaccc aagctggtcc ctaaaatagg attgaaacat ttgattgttt ggcttttgcc
    46981 agttaaaggg gtctcgataa agctggatac atatgacttc gttttctaat tccttcactt
    47041 tttctacttg ttggatgtcg agaaaaatcg gtttagggat gatttgatga taatagcgac
    47101 tataatacat ttcccaacac gaagtgaaac ataaaccttg gtaaaaaaga tcgtatcctg
    47161 gaaattggtt gcaatcgact actacttccc cgttttgttg tttcatttta ggtaaatgtt
    47221 cgatttcatc ctttttctca aacaatagcc gttgagagat ctgttttgta ttgtgataga
    47281 taaactcgct ataagctcgc atataggcga acaccccatg agcaatcatt tttttctgaa
    47341 tgaagtctcg aatcaaaaat tgcttttctt tgaaaacaga gatagacaat acatttttta
    47401 tcaataattg attatcttcc aagcgaaaac tacattcgtt ctcgtcattt cctacaacta
    47461 accaactttc gtctcttacc gatgctagca ttattttttc ttgaagcttt cgaagatcat
    47521 acggatccgc ttgttgtgtg aaagagcgga taaatgttgg ctggatcaac agacgtgtca
    47581 aaatagccca atcgcttatt tcctgttttt tttcttcttc atttaagtct gtgagctgga
    47641 tagtcatcaa taatttatct tcgccaatca ttttctcacc tctttcaaat ctttttataa
    47701 tttaattata accaatgata aagaaaaact aaaactttat gtcttagaaa ccaatttgga
    47761 cgattacatg atagactaag taaaaagaaa caaagaggtg tttacaatgg ggttgaaatt
    47821 tgaacgtaca gataatttag ataaactttt cgaatcattt gctgtcgatc cggaaaaaac
    47881 agttgcacca aaagaagaga tcgatcgatt tctaaaacca cagccacaaa atgaaaagaa
    47941 aaaagacaag aaacaaaagt aagttaagct caaaaaaaga cttaccagcc aaacttttat
    48001 gaaagagttt gactggtaag tcttttttat tctttttatg attcaattgc ttgttcgatt
    48061 gctgcccacg cttcttcttt tccctgtttt gtaacggaag aaaagagaat aaacgtgtca
    48121 ttgcgatcaa aatccaacgc ttttttgatt tcgctctcat gcttgttcca tttaccacga
    48181 gggatcttat ctgccttagt ggcaacaaca attacaggga tatcataata cttcaaaaat
    48241 tgatacatct ggatatcttc ttgagaaggc ttatgacgca aatctactaa agaaacgacc
    48301 gcacgtagct ggtctctagt cgttaaatat gtctcgatca tctttcccca ttttgctcgc
    48361 tcagttttgg atacttttgc atacccatat cccggaacat cgacaaaatg taatgcgttc
    48421 tcgatcaaat aaaaattcaa tgtctgggtc tttcctggct taccggaagt acgggctaaa
    48481 ttctttcgat caatcaatgt gttgataaaa gaagatttcc ctacatttga tcgtcctgcc
    48541 agagctattt ctggcaattg tgtatctgga tattgttttg gtgccactgc acttatgata
    48601 atttcagctt gatggacttt catggtctct ctccttaaca aggtgatgaa taaagcaagc
    48661 ggctgtcgca aaagccaaaa tgacttttac ggcagcctct tttcatcaac ccgctttttt
    48721 ctctgaatct ttatagatta ctgttggctc accagacaat tcagctgctt cttttgtgat
    48781 aatcactttt tcgatgtttt catttgaagg gatatcaaac atcacatcca tcatgatttc
    48841 ttcaatgatg gaacgaagtc ctcgagcacc ggtattgcgt tcgattgctt ttttcgcaat
    48901 ggctctcaac gcttcaggtt cgaattcaag ttcggtatta tctagagaaa gaagtttttg
    48961 atattgtttg actagcgcat ttttcggctc agtcaagatc cgtaccagat catctgttgt
    49021 caatttctct aaagctgcca taacaggtaa tcgtccgata aactcaggga tcaatccgaa
    49081 ttttagtaaa tcttcaggaa tgatatgctg catgacactt tcgtcttcag aaagtttttg
    49141 gttttgtgta ccaaatccaa tcgtcttttc gcccatacga ttcttcacaa tcgtttcgat
    49201 gccatcaaat gcaccaccta cgatgaacaa tatgttcgtc gtatcaatct gaataaattc
    49261 ttgatgtgga tgtttacgtc cgccctgagg tggcacactt gcaacagttc cttctagaat
    49321 tttcagcaag gcttgttgga caccttcgcc ggaaacgtca cgagtaatag atacattttc
    49381 gcttttacgc gcaattttat cgatctcatc aatatagatg atcccttttt ctgcaagttc
    49441 cacattgtaa tcagcagatt gaagcaattt aagcaaaatg ttttctacat cttcccccac
    49501 ataaccagct tctgtcaaac ttgtcgcatc tgcgattgca aaaggtacat tcaatgtttt
    49561 tgctaatgtt tgtgctaaaa atgttttacc agaccctgta ggtccgatca agcagatatt
    49621 gcttttttgc agttcaacat catctgtgtt ttcttgtgct tgctgattga cacgtttata
    49681 gtgattgtat acggcaacag ctaacgagcg ttttgcgcga tcttgtccaa tcacgtagtt
    49741 attcaatact tcaagaattt ctagtggttt agggacttca gtgaattcgc gtacagcttc
    49801 ttcataaaat tcttcatcaa tgatttcttt acataggtcg atacattcat tacagatgta
    49861 gacccctgga ccagctacga tctttttcac ttcttcttgg gttttcccgc aaaaagaaca
    49921 gcgtacggtc tcattgctac ttggattgtc atacatggtc ttcacccctt aacttgcaaa
    49981 aagtatgcaa gaaactatca aagactttac agtcttttac tatcataaca tagtttagta
    50041 aaaagaaaaa gtgtttaaca aaggatcaac tgacctatac ctttgcattt tttactctta
    50101 acaaaaaata aggaactgtg acaaaatcgt gtcacagtcc cttatttcga ataaacaatt
    50161 ttctagaagt agcttcttca gaaatgattt attacttgat ttctattctt tcgcttctgt
    50221 cgctgtacct gtgatcaatt cgattgcttt tttcattgtc acatcatgtt ccagcatatc
    50281 ttctgtcaac acgcgtttga tttgttcgat tggcatgttg tatgtttctg ataattcttg
    50341 gatttctgca ttgatttctt cttctgttgc ttgaagattt tcagcagctg caattgcttc
    50401 gatcacaaga tttgttcttg tgcgcatttc tgcttcacct tcgaattgtt tatgcaagtc
    50461 ttcttctgta gaaccagtta attgatagta catttcagga gagatacctt gacgttgcat
    50521 gttgttcaag aattcgtcca ttgaacgatg tacttcatca tgaaccatca cgtgtggcaa
    50581 ttcaacgatt tctgcgtttt caacagccat acggatcgct gcttcatctt ttgcatcgtc
    50641 cgctgctttt tcttttgttt ctactaattc tttgcgatat ttttctttca attcgtctaa
    50701 tgttgatact tcgtcatcaa catcttttgc gaattcgtca tctaattcag gcacttcttt
    50761 tgcttttact tcatggattg tcactttgaa gactgcttct tttccagcaa gatcttctgc
    50821 ttgataatct tctgggaaag ttacatttac atctagactt tcacctgatt tatgaccaac
    50881 taattgatct tcaaaacctg gaatgaatga gcctgaacct aattcaagtg agtaattttc
    50941 gccttttccg ccatcaaacg cttcgccatc tacaaagcct tcgaagtcga ttactactgt
    51001 atcgccattt tcagctgcag catcttcttt gataactaat tcagcttgtg cttcttgttc
    51061 acgtttgata cgtgcatcca cgtcagcatc tgttacttca cggtcttgtt tttcaacaac
    51121 tagatcttta tattgtccta attttacttc tggtttcact gttacttcag cagtgattac
    51181 ccagtcttga cctttttcca tgctttcaac atcgattttt ggttgagaaa caggatcgat
    51241 gccagcttct ttgacagcag cttcataagc ttctggtaat acagcattca atgcatcttc
    51301 atataaagct tcttcaccgt acatacggtt gaatacttga cgagaaactt tccctttacg
    51361 gaatccaggt acgttcaagc tttttttcac tttattaaac gcagttgtta atcctttttg
    51421 gatttcgtct tgcgcaatcg taaattttaa aacaccatca ttcgtgcctt ttttttcaaa
    51481 tgttgcagtc atttaattcc ctccgagttt agaaattcat tttatacatc aaaaacgttt
    51541 catgcatacc tttaaatagt acactaaccc tttcaaattg taaacatatt gaatggatag
    51601 aatccttgtt tttcataaca tttttatctt tttcactgat aaaatctaat ggaagaagat
    51661 catttgctgc aaaatttttt ctcttttttt taaaaaatct tgtttttcat cttctgtgcc
    51721 ttcatacatc gtttttcctg tacacgcctc tacagtcagt tgaaaccagc gcttcgggtc
    51781 ttcgatgtat gtatcataga caggataaac aattgcagat tgcaacgtga attcttcttt
    51841 taacacggaa ctaagcagcg catcttcatt cccgtaacga tctgaaaata cacataattg
    51901 ctggtaactt gcctgctgct gcggctttgg cagatctttt ggtatgactt tgactaactt
    51961 ttcttcaatc gtcaaataga aaacaggatg gcattcgttc aattgcctaa gtgtctccag
    52021 taattttgcc cttgctaaaa tatggacctc tggcgataca ataagtttac tcgctgtttg
    52081 gataaactca tgataaggaa gctgttcgat ctcatcaata gacgcaagct gacgtgcagg
    52141 ttccaacgaa ggaagttcct ccgatttatt gtggagtgcc ttgatcttct gcctctccat
    52201 ttgtccggat aattcttctg caaattggat tttttcaatg acccgctgct cgaaagcttc
    52261 ataaaaatct gtacttgcta tcaattttct agcatataaa aaatcttgtg tactgattaa
    52321 caagtcaaaa taaaattcag caaactcctc attttgaaga tactgttttt catgcaagag
    52381 tgcttgcttc aatgcttctt ttttctcgtc caactcgtaa agacaaaaaa caagcaggct
    52441 attagcctca aagctttctt tcaactcgta agctcgttga aataattctt ttgcctgctg
    52501 atattgctgg tttgctagtg cttgttgtgc cactcgcatt aaattctcat atttttctgg
    52561 aaaatcaatc ggcttcacgc agtgtcctcc tcttgctcat attcagctca tgttcaatag
    52621 tagcaaaaca aaaaaagcat gacaattaaa aataactgaa gcaccctcta aaagctagat
    52681 tttagatctg acttttagaa ggtgctttca actgttactg ctttttattg ctcatcagct
    52741 gttgacttcc tggttgaacg ctttgatcag attgatcgta acaacacttg tattagtgaa
    52801 aaaatcgccc agatgttgct ttttctgatt aaagactgct ggaagatacc ctaacatcag
    52861 caaaggaaat tttagaatga accggcaagc accttctcta actaaaacgg ttgaccagct
    52921 aagttcttct tcatcaaagc tgatgactcg aataccaaag atcattttcc caatcgtttg
    52981 gccatgattg aatttcgtca ataaaataaa atacgctaga taaataagta aggctgtgaa
    53041 tccgtagaga ctcagataag aatctgaaaa attaagccaa cctagatttt tggcaatacc
    53101 aagtgttaaa cgcgtaatag ctccgataca caaaagatcg accaagaagg caaacattcg
    53161 gataaaaaaa cctgcataga aatacttagg aaaatcattt gcttttggcg gttcatttct
    53221 tgtgtccgta tactttttcc atttacgttg tttctttttg atttcttcgg gcgtcaaagg
    53281 ctctctttca aaagagctca gtaccttttg ggaaaagttg gagtcaggtc ctacagcagg
    53341 ctgctgttgc ttatcttttt cttgttcctt attttcattt gaaagctctg acatgcttac
    53401 tcacctccgt aataatacat tgcttttggt gattccgctg tccctagatt ctcaagaacg
    53461 gataagatct gactagtctc agaaggcttc aatccctgga attctgctag tttacttcct
    53521 aaccatgtac tagcaaaccc agatggcgtg gaagaatatt ctactagttc cgcatcttca
    53581 agctgttgtt cctttcgtat agcttttaaa gcatcttcag gaaatcccaa ttcatcgact
    53641 aaacctactt cttttgcttg gacaccatca taaatccttc catcagcaat ttttttgact
    53701 tcttcttcag atttattccg tccctcgctg acgattgcta caaaacgact atatgcgctg
    53761 tcgatatatg cttgaagcac cgcttcttct tcttttgtct ctggtcgcgt tcctgaaccc
    53821 atatctttca acgctccgct tttaactgtt gtatcttcca cacccagttt ttctagaagt
    53881 cctgaataat tcaatcctga catgatcaca ccaattgagc cggtcactgt ttcttctgtt
    53941 gcaaagattt tatctgcttg agcagaaata tagtagccac cgctagctgc catgtttttc
    54001 atgctgacat acattgggat atcatgttct ttacgaatcg tatccaattt cttagcgatt
    54061 tccgcacttt cgtagacacc gccaccagga gaatttactt ctaaaaagat acctttgact
    54121 gttggatctt cttcaatcgc cttcagttgt tccataaaat ttttatgatt gtaaccttca
    54181 gaagcaaata aacctgaaga ccctcccgca gcaatcgttc catctactga taattttacg
    54241 attttttgcg tactgtctcc ctcttccaac acatttggag ctagttcttc atccccatat
    54301 aaccaactgt tcaatccctc aatttgatcg ttttcctgag gcttagtcaa actagctgaa
    54361 actaacgaaa ccacaaataa tcctgcagca atcagaactg ctgcccaacg tcttttattc
    54421 attctttctc ctttctaata caagtttttt atgacgatca cagtttctga ctgctcagaa
    54481 gtgtcgaacc gctctgcttt ttcttcccgc gcatacccgg aaaacgactc ttttgttaat
    54541 tcatcttcta ccgtaaactc acgagcttga gcaacttcca aggcatcagg tgcgatttct
    54601 tggatgctat cccagccagt atctaaaaat attttcgtat catctgatac accagctgat
    54661 gcttcgaatt tggacaattg tttttttaac attcccagtg tcatgatctc aatttttgaa
    54721 tccattttta ctcctcctct atccgattac tttctattgt accgaactcc tgaaaaagat
    54781 gatagataaa aacccattat tttttgacat aaaaaggaca tttgacaaag aatttgatat
    54841 ataccaattt attttttatt ctttttttgt tgacaagaac attcgcaaaa ggttatgatt
    54901 ttaaatgttt ccagataaaa aacaaaaagg aggatagtta taccttttag gatagcgcca
    54961 ggtctgtgta aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag
    55021 ggactgcact ctacagaaaa tccacaaaaa atgtctgcaa agataaaaca aaaggatttt
    55081 cctgcagctg gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg
    55141 gaattgttgg aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa
    55201 aattagaata ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt
    55261 atctggtcaa agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta
    55321 caggaaatat aggtattggt catacacgat gggcaactca cgggcaacct tctgaagaaa
    55381 acgcccatcc acatacttcc caaagtggac gcttcgtgct cgttcacaac ggcgtaatcg
    55441 aaaactttga agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg
    55501 atactgagat tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg
    55561 cgtttttaaa agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga
    55621 cagcacctga tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg
    55681 atggattcaa tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg
    55741 ttgagattga agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt
    55801 ttgcaggtga catcgtagaa cgttcttcat tcgaagcaca agtagatgct tcagatatcg
    55861 agaaaggtac ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc
    55921 gtcgtatcgc tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg
    55981 tcgatacatt gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg
    56041 cggggttagc aggtaaacag actttggaaa aattgacaca gattcctgtt gaggttcatt
    56101 tagccagtga atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct
    56161 tgagtcaaag tggcgaaaca gcagacagcc gccaagtgct ggtaaaaatc aaccgtctcg
    56221 gctacccttc acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct
    56281 ttacactgct attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg
    56341 cacaaatagc tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa
    56401 cttctcttgt attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg
    56461 tcatcgccca aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa
    56521 atgcctttta cattggacgt ggtgctgact acaacgtttc tcttgaagct gctttgaaat
    56581 tgaaagaaat cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa
    56641 cgattgcttt gatcgaagaa ggaacaccag tgatcggaat catcagtgaa gaagtgactg
    56701 gtgcgcatac tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta
    56761 ttgtctcaga gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt
    56821 atctaactac tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat
    56881 tacggggatt cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat
    56941 aaaagaacaa ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg
    57001 aaaatatctc ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat
    57061 agtaattaac tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac
    57121 cggaaggacg aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca
    57181 cttttttgat tgccggaaca tccatcgcac cgtttttatc acttacgcgg atattcacta
    57241 atttttgcgg atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt
    57301 tcatgatatt cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta
    57361 agaaaatcat gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt
    57421 ctacaacgta acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg
    57481 ctttgtggaa tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat
    57541 ttttttctgc caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc
    57601 caagttcatc caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg
    57661 ctcctttttc aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccgtcat
    57721 tgatatttaa cccgtctgga tttgtgccca ttgtataaaa atctgtttca agatcggcaa
    57781 acaaacgatt aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac
    57841 cggaaaggtc accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg
    57901 gaaattcttc tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag
    57961 catctaataa tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac
    58021 cgaaaaattt gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg
    58081 cgcttgcttt ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct
    58141 ggaacacttc gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac
    58201 ctgagattct tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct
    58261 ggcttaggac ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct
    58321 tgttggcttc accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac
    58381 tcctttaact taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc
    58441 tgatgtttct tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat
    58501 ggttgttgtc gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt
    58561 attttcttgt gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg
    58621 tgtaatctcc acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc
    58681 aattttacga gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc
    58741 accgatcgat gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact
    58801 gaaatcatag ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac
    58861 cgacttgctt ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat
    58921 acttaatact tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc
    58981 atctgtgacc atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt
    59041 gtcacctgta gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc
    59101 agatggtgtg aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt
    59161 ctcaaccgtt actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt
    59221 ttgaattttt agcggaactt catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac
    59281 gcggaacatc cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga
    59341 aagtttgaca gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga
    59401 aatcttgatc ggcacccccg taactgtttg attatacgct tcatttccag aaagcgtatt
    59461 tggaacggac tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa
    59521 actgtaaaga atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc
    59581 ataccgtcta ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatt
    59641 agttctctac gcaagattgc caaatattct tgctgggata agccagccat cagttcatta
    59701 tctaacgtga tgctgacgtc cccggtttct tcagagacaa cgatggtaat cgcgtcactg
    59761 acttcgctta taccgacagc tgcccggtgt cgagtcccga attctttagg gatcaacata
    59821 ctttctgata gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact
    59881 gcaccgtcat gcagcggtgt attaggaata aagatattga tcagcagctc cccagtgata
    59941 tctgcatcta aagcaatccc tgtctcaata tactcatcta atccagtatg acgttcgata
    60001 gtgatcaacg caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag
    60061 atcatcttct catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca
    60121 agatgttcca gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg
    60181 tacgtaatga cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg
    60241 attcggataa caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc
    60301 agcagttgga tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc
    60361 aaaaaattca gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa
    60421 agttccccga tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag
    60481 tatatcatat gttttaattt tagaggctga tatgctcgta tttttcttga gaaaaacgca
    60541 taattttcaa gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa
    60601 cttcagagaa ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt
    60661 gttccatttt tttacgtcgt tctgctctgg cagctcttct agcagctctt ctttcttctg
    60721 cttcaaggtc cgtcgttttt tcttttctag tcttaacggg tacatcgata gattcctctg
    60781 gttcaagtcg tttcttgatt ttttctaatt ctcccgtcag tgcagcatag ttgtaaaaac
    60841 gtgttttagc gtcgtggaca gtcttttcaa ataaagcttt tgcaagattt ggatttgcgt
    60901 tatctagcga ggaaaagcga acttgtttcc tcatgaaatc aggcatagca gagaaatcag
    60961 gttttttgta gtccaaagtc attgggttct tgtttttttc gaccattgta gggttatatc
    61021 gatataatga ccaataacca gaagaaacag cttcttttgc ttctttaagc gattctttca
    61081 ttccgccaag caagccatgt gtgatacaag gcgtataggc aataatcaga gaaggaccag
    61141 gatacttttc tgcttcttca aatgccttga tcgtttgcat ttgattggca cctgaagcaa
    61201 tttgcgccac ataaacattt ccatatgtca tcgccatcat tcctagatct ttctttgaag
    61261 catactttcc actagccgaa aatttagcga ttgccgaagc tggtgttgct tttgaggttt
    61321 gaccgccagt attggaatag acttcgttat ccaaaacaag gatattcacg tctgctccgc
    61381 tggcaagtac atgatcgatc ccgccaaaac caatgtcgta agcccatccg tctccaccaa
    61441 tcatccattg gctgtttttt acgaatagat cctttctctt gtatatatcc tccagttcag
    61501 ggaaaattga tcgttcgctt tcgatcgcag cttgcagttt tgctgctctt tgctgcgttc
    61561 cttcactctc aaacatgtgt actaaccagt cttccatcaa ttctcgtagt tcttctgata
    61621 cttttggcaa tacttctttg attgaacttg ccaaagcctc gcgacgagtc tgtgccgcta
    61681 gaagcatacc ataaccaaat tcagcattat cttccaataa agaatttgac catgcaggcc
    61741 cttgaccaca ttcattggtc gtataaggag aagcaggaga agcaccgccc caaatagaag
    61801 aacagcctgt cgcattcgcg atcatcattc gatcaccgaa catttgtgtc aataatttta
    61861 cataaggtgt ttcgccacag cctgagcaag cgcccgagaa ttcaagaagc ggttgattga
    61921 attgtgtaga caagacagta ttctttcctt tgactggatt tgctttttgt cttaatgtca
    61981 ttgcaaaagc ccaattcaca gcttgttctt tctgttcttc ataaggcttc atcactaaag
    62041 ctttttcttt tgcgggacaa gcctctacac acagaccaca acctgtacag tcttccactg
    62101 aaacttggat acggtatttt acgccgtctg cgcctcgcat ttctctcacg ataaatcctt
    62161 ctggcgcttc ttccatttcc tcttcatctg ctaaaaatgg acggatggca gcatgaggac
    62221 aaacaaaggc acattcatta cacatcgtac agcgatcact aatccactca ggtacttcta
    62281 aagcgacgcc ccgcttttcc atagaagccg ttcctaaagg catttcgcca gttgtcattc
    62341 catttgctac aagtgtacca acagagagtt gatttccttc ctgtgcattc actggttcaa
    62401 gtatttcttg tatataacca gtgttccttt tattgatttt ttcaggcatc tccaacgttc
    62461 tccaatggtc tgggatcgcg acttgatgaa gcagttcggt cgtccgatcg attgcttgta
    62521 tgtttttttc tacgatagcc attgatttat gtccatagct tttcagggct tcttctttta
    62581 gcagcggaag cacctcatca aaaggaatga tgtcagctaa tttaaaaaaa gccgtttcca
    62641 ttgccgtatt gatccggcgt cccaaaccga cttcttgggc caatctcatg gcattgatcg
    62701 tatagaatct aatgttattt tcagccaagt aacgttttaa ttttaagggc agatgcgttt
    62761 ctaattgttc gtcgctccaa agagtattca ataaaaaaat gccacctggc ttcaatcctt
    62821 tgaccaagtc atagctatgc aggtaagctg gtgtgtgaca ggcaacaagg tccgcatgct
    62881 cgacaagata cgctgaacgt atcggcgtat ctccaaaacg aagatgagag acagtcagac
    62941 cgccagattt tttcgaatca taataaaaat agccttgcgc atatttatcg gtgtgatctc
    63001 caataatctt gatagctgat ttatttgctc caactgttcc gtcagatcca aatccccaaa
    63061 acttggcctg gaatgtttgc ggttctgtca aatccagact ttcctttggt tccaaagatt
    63121 gataagtcac atcatccacg atccctatgg taaaccgttt tttgcgtatg cttgggtctt
    63181 ttttcaattc atcaaaaact gctgagattt ggtcgggagt cacatcttta gaccccaatc
    63241 cgtagcgacc accaataaca gccgggcgaa gttcagaatc atataacgca ctttgaacgt
    63301 ctaataagag aggttctcca cctgcccctg gttctttact tcgatcaaga acagcaattg
    63361 tttttactgt atgaggcaac ttttgcacga atgtttccac tggaaaagga cgataaagat
    63421 ggatattcaa aaaacctgtt ttccgtccgt ttgcattcaa gtaatcaatc gtttgttcaa
    63481 tcgtctgtgc aactgatccc atagaaacaa tgacttcttc cgcatcgtct gctccgtaat
    63541 aagtcaccaa gtcataagaa gttcctcgta atcggttgat ctctttcata tatttttgaa
    63601 cgatttcagg taatttatca taataggggt tgatcgtttc ccgttgttga aaatggatgt
    63661 ctggattctg gttcgtacca ctaacagtcg gatgattggg attcatccct cgtttacgaa
    63721 atgaagctaa tttctcctga ttgatcagag gagctaattc ttcatattcc aaaacttcga
    63781 ttttttgaat ctcgtgactc gtacggaatc catcaaagaa attcaaaaaa gggacttctc
    63841 cttcaataga agcaagatgg gcaacaggtg ctaaatccat cacttcttgt acactgcttt
    63901 cagctaacat agcaaatcct gtttgtcttg cagccatcac gtctccgtga tctccgaaaa
    63961 tattcaacgc atttgtcgtc actgcccgac tagcaacgtg gaaaacactt ggcagtagtt
    64021 ccccagcaat cttgtacata ttcggtatca tcaaaagcag cccttgtgaa gcggtatatg
    64081 tagttgtcag tgcaccagtt ttcaatgatc catggaccac accagctgct cctgcttcgg
    64141 attgcatttc tactactttt actggttgac cgaatacgtt ttcttttcct gctgctgacc
    64201 attgatctac taattcagcc atggtcgaac tgggtgttat tggatatatt gcagcaatct
    64261 cggtaaatgc ataagaaata tatgcggctg ccgtattgcc atccattgtt ttcatttttc
    64321 gcatgattca tcatccttgt tcatattctc tcttattatc tgttccatta taacgtaaaa
    64381 catgccattt ttttctttta tttataaaaa tattttacat gtatctattt gaattggtca
    64441 tctaattttt agacaaacag tctaaatcgt tgcctttttt tgtcagacat gtataaacta
    64501 taagcgaaag aggtgtttta acatggatat atcagtgatt gatgcaacga aaacaaatac
    64561 acaaaaagga atcctttatg gttcatcgaa tgctcctaaa aaaatggtcg aattcatcaa
    64621 cttagcttgt ccgtattgcc gacaatggtt tgaagaatct tatgagctat tagaagaagc
    64681 agtccaaagc gggcaattgc agcgagtgat caaattgttc gataaagaaa aagaaagctt
    64741 acagcgaggg aacgtgatgc accggtatct cacaatcagc gatggccaaa aagcgatcaa
    64801 agagatcaaa caaatattcg atactcaaga cgagtggaaa catctttctc tccaagaagt
    64861 agcggatttt gcagtagata aactaaagct gacagaacaa aaagacgaac agctgagcca
    64921 agctgtcatc aacgaagctg agcaagcaca tattcgattt gttccaactg tcatcttggg
    64981 taaagaaatc tttgatgaat ctatttcaat agaggaatta aaagaattga tccaaacaaa
    65041 ataaaaaaat aaggagcgtg ggacaaaagt aaagaacact tttgtctcac gctctaaaca
    65101 cgtataaacg gcggaagcag aagcaactcc ttcttatttc ttggagttaa acgcttctgt
    65161 cccagcctcc ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca
    65221 tttcttatga caagctaagc aaattatctc caccaaataa tttattcata tttttgactt
    65281 gcgcatacta actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta
    65341 atatttatgt acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc
    65401 aattctactt caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg
    65461 ttgagctagg tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac
    65521 caaacgcaag atggcaaaca caaatgcata cgcatctgta tt
//
LOCUS       DARPZJ010000012        59532 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.012, whole genome shotgun sequence.
ACCESSION   DARPZJ010000012 DARPZJ010000000
VERSION     DARPZJ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.012"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(341..1651)
                     /locus_tag="SLE23_000950"
     CDS             complement(341..1651)
                     /locus_tag="SLE23_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEI8467868.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1663..3081)
                     /locus_tag="SLE23_000951"
     CDS             complement(1663..3081)
                     /locus_tag="SLE23_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8467869.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3321..4889)
                     /locus_tag="SLE23_000952"
     CDS             complement(3321..4889)
                     /locus_tag="SLE23_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEI8467870.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4893..5303)
                     /locus_tag="SLE23_000953"
     CDS             complement(4893..5303)
                     /locus_tag="SLE23_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HEI8467871.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5300..6223)
                     /locus_tag="SLE23_000954"
     CDS             complement(5300..6223)
                     /locus_tag="SLE23_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HEI8467872.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6220..7098)
                     /locus_tag="SLE23_000955"
     CDS             complement(6220..7098)
                     /locus_tag="SLE23_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HEI8467873.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7085..8422)
                     /locus_tag="SLE23_000956"
     CDS             complement(7085..8422)
                     /locus_tag="SLE23_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEI8467874.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8425..9528)
                     /locus_tag="SLE23_000957"
     CDS             complement(8425..9528)
                     /locus_tag="SLE23_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEI8467875.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9602..11110)
                     /locus_tag="SLE23_000958"
     CDS             complement(9602..11110)
                     /locus_tag="SLE23_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8467876.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11076..11768)
                     /locus_tag="SLE23_000959"
     CDS             complement(11076..11768)
                     /locus_tag="SLE23_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEI8467877.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11790..12764)
                     /locus_tag="SLE23_000960"
     CDS             complement(11790..12764)
                     /locus_tag="SLE23_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8467878.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13064..13936
                     /locus_tag="SLE23_000961"
     CDS             13064..13936
                     /locus_tag="SLE23_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8467879.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14394..16592)
                     /locus_tag="SLE23_000962"
     CDS             complement(14394..16592)
                     /locus_tag="SLE23_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8467880.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16824..17816
                     /locus_tag="SLE23_000963"
     CDS             16824..17816
                     /locus_tag="SLE23_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8467881.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17876..19297
                     /locus_tag="SLE23_000964"
     CDS             17876..19297
                     /locus_tag="SLE23_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HEI8467882.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19290..20789
                     /locus_tag="SLE23_000965"
     CDS             19290..20789
                     /locus_tag="SLE23_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HEI8467883.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20828..22222
                     /gene="uxaC"
                     /locus_tag="SLE23_000966"
     CDS             20828..22222
                     /gene="uxaC"
                     /locus_tag="SLE23_000966"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEI8467884.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22381..23064
                     /locus_tag="SLE23_000967"
     CDS             22381..23064
                     /locus_tag="SLE23_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HEI8467885.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23066..23902
                     /locus_tag="SLE23_000968"
     CDS             23066..23902
                     /locus_tag="SLE23_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEI8467886.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23913..25667
                     /locus_tag="SLE23_000969"
     CDS             23913..25667
                     /locus_tag="SLE23_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467887.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25943..26284)
                     /locus_tag="SLE23_000970"
     CDS             complement(25943..26284)
                     /locus_tag="SLE23_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEI8467888.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26352..28523)
                     /locus_tag="SLE23_000971"
     CDS             complement(26352..28523)
                     /locus_tag="SLE23_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEI8467889.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGATETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28692..29591
                     /locus_tag="SLE23_000972"
     CDS             28692..29591
                     /locus_tag="SLE23_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEI8467890.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29662..30519)
                     /locus_tag="SLE23_000973"
     CDS             complement(29662..30519)
                     /locus_tag="SLE23_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8467891.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30504..33206)
                     /locus_tag="SLE23_000974"
     CDS             complement(30504..33206)
                     /locus_tag="SLE23_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEI8467892.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33219..34508)
                     /locus_tag="SLE23_000975"
     CDS             complement(33219..34508)
                     /locus_tag="SLE23_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEI8467893.1"
                     /translation="MAYKDIPNSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34658..35704
                     /locus_tag="SLE23_000976"
     CDS             34658..35704
                     /locus_tag="SLE23_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8467894.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35706..37859
                     /locus_tag="SLE23_000977"
     CDS             35706..37859
                     /locus_tag="SLE23_000977"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEI8467895.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38332..39783)
                     /locus_tag="SLE23_000978"
     CDS             complement(38332..39783)
                     /locus_tag="SLE23_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8467896.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39780..41504)
                     /locus_tag="SLE23_000979"
     CDS             complement(39780..41504)
                     /locus_tag="SLE23_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8467897.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41497..42111)
                     /locus_tag="SLE23_000980"
     CDS             complement(41497..42111)
                     /locus_tag="SLE23_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEI8467898.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42456..43913)
                     /locus_tag="SLE23_000981"
     CDS             complement(42456..43913)
                     /locus_tag="SLE23_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8467899.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43954..44874)
                     /locus_tag="SLE23_000982"
     CDS             complement(43954..44874)
                     /locus_tag="SLE23_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8467900.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44886..45833)
                     /locus_tag="SLE23_000983"
     CDS             complement(44886..45833)
                     /locus_tag="SLE23_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8467901.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46312..47031)
                     /locus_tag="SLE23_000984"
     CDS             complement(46312..47031)
                     /locus_tag="SLE23_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEI8467902.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47080..48726)
                     /locus_tag="SLE23_000985"
     CDS             complement(47080..48726)
                     /locus_tag="SLE23_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8467903.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48905..49495
                     /locus_tag="SLE23_000986"
     CDS             48905..49495
                     /locus_tag="SLE23_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8467904.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49587..51092
                     /locus_tag="SLE23_000987"
     CDS             49587..51092
                     /locus_tag="SLE23_000987"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEI8467905.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51176..52528)
                     /gene="celB"
                     /locus_tag="SLE23_000988"
     CDS             complement(51176..52528)
                     /gene="celB"
                     /locus_tag="SLE23_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEI8467906.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52528..53046)
                     /locus_tag="SLE23_000989"
     CDS             complement(52528..53046)
                     /locus_tag="SLE23_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467907.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53062..53388)
                     /locus_tag="SLE23_000990"
     CDS             complement(53062..53388)
                     /locus_tag="SLE23_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEI8467908.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53401..55380)
                     /locus_tag="SLE23_000991"
     CDS             complement(53401..55380)
                     /locus_tag="SLE23_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8467909.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55401..55715)
                     /locus_tag="SLE23_000992"
     CDS             complement(55401..55715)
                     /locus_tag="SLE23_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEI8467910.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55883..56176
                     /locus_tag="SLE23_000993"
     CDS             55883..56176
                     /locus_tag="SLE23_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEI8467911.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56254..57366)
                     /locus_tag="SLE23_000994"
     CDS             complement(56254..57366)
                     /locus_tag="SLE23_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8467912.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57519..57743
                     /locus_tag="SLE23_000995"
     CDS             57519..57743
                     /locus_tag="SLE23_000995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467913.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            57753..57932
                     /locus_tag="SLE23_000996"
     CDS             57753..57932
                     /locus_tag="SLE23_000996"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467914.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58126..58296
                     /locus_tag="SLE23_000997"
     CDS             58126..58296
                     /locus_tag="SLE23_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8467915.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58720..59469)
                     /locus_tag="SLE23_000998"
     CDS             complement(58720..59469)
                     /locus_tag="SLE23_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8467916.1"
                     /translation="MVELTKANRLTPGGVVLTKIDDQSGEVLQEAVFELQDANGTVLQ
                     SGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENR
                     LTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQL
                     VETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPK
                     TGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17805 a        12167 c        10408 g        19152 t
ORIGIN      
        1 agcaactttt atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt
       61 ttcgatttcg tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat
      121 ttgtcaagaa cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt
      181 taacgactta gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc
      241 ataaaatgtt tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg
      301 tcaagctaaa atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat
      361 tgtttgcagc tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt
      421 gtactgcttc gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat
      481 cttctatagg cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac
      541 ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct
      601 ttgattcagg tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat
      661 tgctattttt tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta
      721 catcaatcat attcagattt tctaccctga tattttcgat cactccccct ctttcttttg
      781 aagatttcat tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt
      841 cactaactcc agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac
      901 atctagcaac ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc
      961 cagacttaat agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat
     1021 ttgttgaaga atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta
     1081 ctttttctac taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct
     1141 gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac
     1201 gtttaatagc ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc
     1261 cgcttttttg atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta
     1321 ttccttttcc ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc
     1381 atttcatttc tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc
     1441 tccccttgag gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg
     1501 ctccgactaa ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat
     1561 cgattgcttt ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca
     1621 aagcattgat aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt
     1681 tttcaattct tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa
     1741 aatgattgcg gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct
     1801 ttcttgtact aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag
     1861 tgccagcata aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga
     1921 atttactcca tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat
     1981 cacgtcagta atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat
     2041 aaataaaaga atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta
     2101 catacatgaa gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt
     2161 cagctttgta gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac
     2221 agacattgct tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc
     2281 taaaatctga ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt
     2341 agctaacaaa ccttttacca actgagaagc agatactttt tcgtttttga caactcttac
     2401 tctttcagta gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc
     2461 gattgaaatc caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt
     2521 atacattaaa atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct
     2581 tcggaacgtg gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc
     2641 tccatacggg atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat
     2701 ataagcaatc ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt
     2761 cactaagcaa aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt
     2821 taactctgag acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct
     2881 cgaaatcaag aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata
     2941 aatcatcaag aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat
     3001 gtagcctatc ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt
     3061 aacagcattt tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa
     3121 ttataactct ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt
     3181 gacagataaa aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt
     3241 tacataacaa tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc
     3301 tcatttatta aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa
     3361 tcagcataac ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca
     3421 gtaaaccctc ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca
     3481 gttgatacgt ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa
     3541 gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat
     3601 tctatcatac gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa
     3661 ttggattcat ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat
     3721 tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt
     3781 tcgaaggtag attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt
     3841 gtatcacacc aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct
     3901 ccttcaaatg tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca
     3961 atcattattt cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac
     4021 gtccaataca cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt
     4081 ctggtacaaa gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt
     4141 cctgtacatt gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga
     4201 tcaagctcgt aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt
     4261 cctgtaccgc cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt
     4321 gcctccgttt tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc
     4381 ttcttctctg catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga
     4441 cgataatccc atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa
     4501 gaaggatcaa agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca
     4561 gatgcagtga tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct
     4621 gtgtaaacaa gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca
     4681 tttgtaggat ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag
     4741 ttgactaaat ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca
     4801 ataatgtaat accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa
     4861 ataggatttt tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga
     4921 tataaactga atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga
     4981 gtgccaatca acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat
     5041 tttcctttag cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca
     5101 acggcaaaca gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt
     5161 gaatgatcta cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt
     5221 aaagtaactg ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc
     5281 aatagttccc attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag
     5341 gtcttttgat cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat
     5401 ttttcttgtc atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg
     5461 cttcaaataa gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat
     5521 caggttctgc agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg
     5581 tagatgctgc tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat
     5641 gaaaaacggc atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt
     5701 cataggtctg acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat
     5761 ctttttgcaa atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac
     5821 agttttttaa agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt
     5881 ctcctggacc tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta
     5941 agaaaaaagt agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg
     6001 caaaacgatt accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc
     6061 tgctttctat atattcatca tatcttcctt cttttactat caagaccttt ggatggctat
     6121 ccggcaggcc tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat
     6181 ctatagcatt ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa
     6241 ttgtttccaa atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga
     6301 agaaaagttt tctggactac ccattgattg atactttttg tccagccctt ttctcagctt
     6361 cagtacgcct tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg
     6421 cggagcgatt ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata
     6481 gtaataaaac ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg
     6541 tgccgctaga tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa
     6601 taagcctccc atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt
     6661 ctccaaataa tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc
     6721 tgttaataaa aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc
     6781 ccaagcatca atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg
     6841 agaagctaag taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc
     6901 gtgagaatgc aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag
     6961 ggctggtact gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt
     7021 ttgtttttct cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa
     7081 aaaatcattc aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg
     7141 attgatttga ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg
     7201 gtccctcgtg attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat
     7261 aaaatccttg tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg
     7321 catcttgggc catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg
     7381 ctaatccata aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat
     7441 ggatccttct gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat
     7501 acggttcttt ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca
     7561 cattatccat gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc
     7621 tagatttcaa tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat
     7681 tacgaatact accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg
     7741 tgcaatttgt gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg
     7801 ccttgattgc aatacagtca tctcccacgt caatatggca attactaata cgcacatttt
     7861 tgcatgattc tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca
     7921 agttatcaaa cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga
     7981 tcaatttaat atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac
     8041 gaggataagc gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc
     8101 catctaatgt accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg
     8161 aagcataaac ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg
     8221 gatcgtcaga gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta
     8281 aaaataaagc tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac
     8341 ttgctgcagc atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc
     8401 caaatgtcaa aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa
     8461 tgcaccaacg cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga
     8521 accatctcgc tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag
     8581 ccagccttct tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac
     8641 ttgtggaagc cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta
     8701 aacaaacata ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt
     8761 tacttgatac catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt
     8821 ttctagaatt tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc
     8881 tgctgcagcc atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt
     8941 ttttggatca gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt
     9001 ttttggatcg aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc
     9061 tttttcttca ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc
     9121 atccaaccaa atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg
     9181 tggatggttt gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc
     9241 tgtttctttg tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc
     9301 ttcaacgctg tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt
     9361 tatgaaatca aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag
     9421 tacgacgcca tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg
     9481 tgttctttcc atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc
     9541 tttaaaaatt aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat
     9601 attactgtgc cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt
     9661 gtgctttcca gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt
     9721 attgcaccgt agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg
     9781 gtgaatccaa tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt
     9841 gattagagaa ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac
     9901 gagagcttga taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag
     9961 aaccatcatc attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca
    10021 catcttcttc taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt
    10081 ttacttgaga tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat
    10141 gataaccgcc gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt
    10201 gaataccttg acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag
    10261 ttcttccttg tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg
    10321 ccaaatagcc attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg
    10381 tatcaaattc tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa
    10441 aataagaagt gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa
    10501 aaccaactgt gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta
    10561 cttcataaag ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt
    10621 ttcgaatgac taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac
    10681 cgtcgatact cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt
    10741 ttaaatattc tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt
    10801 ttttcaacat cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag
    10861 ttgttaatct ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg
    10921 ttttttcttc gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat
    10981 ttaaccaagt gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc
    11041 tgccgcatgc ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg
    11101 cttttttcat aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt
    11161 tctgtatatg agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact
    11221 gcggaaaaga agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc
    11281 atcagataaa tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat
    11341 ccgaataaaa atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg
    11401 attgggaaaa tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc
    11461 ctaagatacc aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca
    11521 tatatccagc tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt
    11581 ttcgtcaaag gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca
    11641 tacgatgcag gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga
    11701 aaattcaaat aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac
    11761 tgcagcatat ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg
    11821 gcaatcttat tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt
    11881 gctgtactga aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa
    11941 atttctgcaa cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag
    12001 tctaatgtct gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc
    12061 aatgtaacat gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac
    12121 aactgtgtat cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct
    12181 ttccagatca cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg
    12241 attttttcaa atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa
    12301 aatacataag taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc
    12361 gtttgaatcc cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg
    12421 attggcatcg gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat
    12481 aatgtaaaga atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga
    12541 cttcccatta ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata
    12601 ggaagatacc taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat
    12661 ttattcgttt tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc
    12721 gatagcgtca gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt
    12781 ttgtgaatgt ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat
    12841 catttttacc gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat
    12901 aaagtgtatt ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga
    12961 cacttagcat aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata
    13021 gaaacagaaa catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc
    13081 tataggagaa agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat
    13141 ctgtatcgtt ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt
    13201 cgcgaaaaag tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct
    13261 ttctacgccg accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac
    13321 gatcgtcagt atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt
    13381 tggtcgaggt ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat
    13441 tccaacgttc ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct
    13501 gcctgtggct gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc
    13561 ggatagtttg gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa
    13621 aattatgctg ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac
    13681 ttactggaac acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat
    13741 acagattctt ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc
    13801 cgttgatgtg attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt
    13861 gcctatgctg attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg
    13921 ttctgtcaaa gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag
    13981 cttcaagaaa taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc
    14041 ttatttttcg aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt
    14101 cagccttgag cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa
    14161 taagaagcga ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat
    14221 agcctgtctc ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca
    14281 gttctttttg cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta
    14341 ttctaacttc ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa
    14401 tatttttttc gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa
    14461 ttttgcggat ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct
    14521 ttcaaccatt tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct
    14581 cctgtttcct ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg
    14641 atcacatcta aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc
    14701 gacaaatttt taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact
    14761 aattgttcta aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca
    14821 taaatttgtt tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga
    14881 acgagttcat tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt
    14941 gcaaacaatg catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga
    15001 atggcttcaa acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga
    15061 gcagcaggaa cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa
    15121 tacagggctt cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg
    15181 ttactgatgc ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt
    15241 cggcaatact ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata
    15301 gtggcttgca tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt
    15361 tccgtgatca tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct
    15421 tctaacagat cgatttgaac caaagctgta taatagcagt cattttgaga actataacca
    15481 aattgctgca accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt
    15541 acaaatagcg tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt
    15601 tctcctatga tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct
    15661 tttgatttaa gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa
    15721 aataagtagg aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg
    15781 attctcagat tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc
    15841 caattattat aatctgattt cagtactata tacgttttat ctttttctct tatcactttc
    15901 agctgattgt aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact
    15961 gtctgagtag taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt
    16021 tcaccaacaa cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt
    16081 tctttttcaa acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa
    16141 aataaattat ttttgttatt tatgtacttc tgttgatact tttcaatttc ctcttcggtc
    16201 agttgactca acgatccatt gattactccc catttaccag ccaaactgac taaatcataa
    16261 ttattatcat ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa
    16321 gtggagtaat ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa
    16381 ccatacgtag aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact
    16441 tgcctgagca aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc
    16501 tggtaaatga ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa
    16561 aatattttat aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa
    16621 aggctttcat ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc
    16681 aagaatagca taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat
    16741 atcaaagatc tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt
    16801 gaaaaagtaa ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa gcagctggcg
    16861 tttctcatac gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa
    16921 aacaaaaaat acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag
    16981 gtttagtgaa tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa
    17041 cttcatcaaa tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt
    17101 acagtttatc tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct
    17161 acgatggact gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca
    17221 aagaaaaaga atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca
    17281 acgtcactgc cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg
    17341 gacatacgaa gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg
    17401 aaaaaggggt attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt
    17461 taacaggaga ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt
    17521 ctgacctgcc tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag
    17581 ctgtacattt agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt
    17641 ctccagtcgt ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa
    17701 tgtgtcaaga aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat
    17761 ctaaaattga gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta
    17821 caagtaattt tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa
    17881 aaaactgaca aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg
    17941 tgaaggcaat tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca
    18001 attgtttaaa ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat
    18061 gaaccagcaa gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt
    18121 tgatacttcc gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga
    18181 tgcttatcta tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga
    18241 ggcaggaatc caattcgtgg agactgataa tttaacagat actcccccac agagcctccc
    18301 gggcaaactg acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat
    18361 cattccttgc gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta
    18421 cgcagaaaaa tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt
    18481 ctgttgtagt ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt
    18541 caatcaacgg cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg
    18601 ggtgatcgaa gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa
    18661 tgtcatcatc acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg
    18721 accgcataca gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt
    18781 aatgaaagat cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc
    18841 tatgctttct ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt
    18901 cttgaatcct tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt
    18961 cagcacccgt ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc
    19021 gttaatcact gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc
    19081 acatgatgat gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc
    19141 tattcctcga ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa
    19201 tgtgacagat acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt
    19261 attacaagaa atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat
    19321 taaatcgacg agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga
    19381 cgattgatca gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat
    19441 tgggtgattt gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga
    19501 cgacagacgt aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg
    19561 gtgaattgga ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc
    19621 gaacatttca aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt
    19681 tagtacctac cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg
    19741 aaaaacatcc agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct
    19801 gttcgcagct tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc
    19861 atcccaatgc cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg
    19921 aattcaaaaa aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag
    19981 atgtttacga tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg
    20041 aaaatgacca gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg
    20101 gttctgatgg tctatcggga ataactgcta atcctttact tggtgcattt tctgactact
    20161 tgattgctca aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac
    20221 aagtattgat ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca
    20281 atgacttcaa acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg
    20341 gtaataaagc aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat
    20401 caggaagctc tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc
    20461 ttagtttatt gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg
    20521 attgccagtt ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa
    20581 cggtcaaggt atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta
    20641 atgcaggcgt cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa
    20701 tcatcgctgt agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg
    20761 ccatttttaa aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg
    20821 aagatttatg tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta
    20881 ccattcctac gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga
    20941 aatttacgaa aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta
    21001 caaatggcgc ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc
    21061 tgattttgaa aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct
    21121 ttacagttgg tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga
    21181 agaaaatgca gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg
    21241 ccgtcgggaa atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc
    21301 agacgacttg cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc
    21361 ttcattccgt ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac
    21421 actactggaa gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt
    21481 agggcagcgg atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga
    21541 catcttacgc tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg
    21601 agctaacaaa ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca
    21661 tttgacccac ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg
    21721 taactgtaat acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa
    21781 tgatctttct ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca
    21841 gttgccaaag acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt
    21901 gatgggctgt ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta
    21961 caacgatact cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt
    22021 ggggaatttt gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga
    22081 atatttccgt cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc
    22141 tgaagatgaa caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa
    22201 ttactttggc ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata
    22261 gtgaaataac ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc
    22321 gtcttcttct cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac
    22381 atgcctacta tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt
    22441 cccgagacag gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat
    22501 aaccaagcaa agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt
    22561 ctagcttcac agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag
    22621 aaaatccaag aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata
    22681 ttttttgaat gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga
    22741 cgagattact tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg
    22801 atgcgtgcat ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa
    22861 gaattgttcc agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct
    22921 gatacttgta aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc
    22981 gctgataaag ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct
    23041 aattatttac aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga
    23101 tttagatgtt cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca
    23161 tatccaattt gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact
    23221 tgggagtgct gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt
    23281 aggatgctat atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac
    23341 tttcaaacag caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac
    23401 cggtagtgtc tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc
    23461 cagaaattct atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt
    23521 tgaagcaggg atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga
    23581 agtagcttca ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa
    23641 tcatgctgat caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac
    23701 agcgcttcat ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg
    23761 caagggctgt ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat
    23821 gtacgccact cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca
    23881 gtttatttac caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc
    23941 aaaaatatca tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc
    24001 gttttgccat gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga
    24061 tcgctattgc caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca
    24121 tttatttcaa cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt
    24181 ttcatgtaaa ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc
    24241 ttatcaagaa aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa
    24301 tccagtcaaa gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg
    24361 tcagcggatt aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa
    24421 gtcctgttgt tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct
    24481 ttttccgtaa aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt
    24541 ctgcaaaagt gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa
    24601 aacacgaaac aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact
    24661 tagatatcct gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc
    24721 tgatttgttt gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg
    24781 tcgtgatgta tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc
    24841 tgattcctac gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg
    24901 ctggcgatgt agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc
    24961 gttttgagga tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt
    25021 ctctagaggt gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat
    25081 ctacactcct taacttattg attggattta tccagccgac ttcaggaaaa atttttctag
    25141 atgatcagcc tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc
    25201 ctcaaaccac tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa
    25261 acgtatcaaa agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg
    25321 accagcttcc tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg
    25381 gccaaaagca acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc
    25441 tagatgaagc aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga
    25501 attacctgac agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag
    25561 aggcagataa aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa
    25621 aactgttagc tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag
    25681 ctatgacaag acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact
    25741 cctcggtcac aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct
    25801 tgtaactcag agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag
    25861 cctatcggca ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc
    25921 tctgttgttt cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga
    25981 tacggttcaa gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga
    26041 ttacttcttc tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc
    26101 tgaactcttg tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt
    26161 tgaacagttt gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt
    26221 tgaattctgg taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg
    26281 acatgttatg ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt
    26341 tttcaaaggg gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt
    26401 ccctgaacgc cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca
    26461 ccatattgat tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt
    26521 ccaacttgat ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat
    26581 cctgtttttg aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca
    26641 acatttccac ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat
    26701 gtcgaaatca ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca
    26761 tcgaaattag tttctgtggc tcctgttttc cctgctatcg tataacctgc aggattcgca
    26821 gcagccgctg ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt
    26881 tcctttgata tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc
    26941 gaatcaacga ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca
    27001 ctgtaagcac ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag
    27061 ccataatact tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct
    27121 ttttgtaaac cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca
    27181 gcttgataca tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa
    27241 ctttgcggtt cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta
    27301 tatacgctta atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg
    27361 aatcctctaa agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc
    27421 ggatctaaag ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat
    27481 aatgcactgt tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta
    27541 tagattttat agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct
    27601 tcatcgatca ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat
    27661 gtgtcattaa gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg
    27721 atttttccgt tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt
    27781 gggtgatcga tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc
    27841 tcagacagcg taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca
    27901 ccccataccc cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg
    27961 ctgtacttct tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt
    28021 tggtctaatg tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc
    28081 cctgatgttc cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca
    28141 aacccgtgat gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag
    28201 ggagaaatcg cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct
    28261 tcgtttttct tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca
    28321 tttgcttgtt ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca
    28381 atcagcaaaa tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg
    28441 aattgtccga gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt
    28501 tctaaaatgc tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta
    28561 ttttaccata gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt
    28621 acgttagtgc aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat
    28681 atgttttaaa aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa
    28741 tcacgatcac tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg
    28801 aatggttagt tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca
    28861 atcaacaacc tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat
    28921 tcgaagaaac agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg
    28981 ttttatatga agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc
    29041 caaatgaacc gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta
    29101 aacagcaacg accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat
    29161 ttgcaaaaaa tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct
    29221 atcggagata tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata
    29281 aaattggacg agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga
    29341 gcgccttgac acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg
    29401 ttttggaaac cggacgtaca caccagatca gagttcattt agctcataag ggacatccga
    29461 tcgttggaga ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag
    29521 aactgcacat gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat
    29581 tatgggaata gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt
    29641 ctttttgtgt aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc
    29701 gataatccca ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt
    29761 ttccatataa ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc
    29821 ctgattcatt accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt
    29881 gatcagtgct tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag
    29941 atcttgccct ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa
    30001 acaatcttta tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca
    30061 aatatgtccc atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc
    30121 tgcaccgatt cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc
    30181 ttgcttcaat tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt
    30241 gtagcgttcc ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc
    30301 caaaacgtat ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat
    30361 cccgattccc ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc
    30421 tggtgttgtg gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca
    30481 cacaaatttt gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg
    30541 attgtccgaa tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca
    30601 agcagattca atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga
    30661 ctagacatat tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct
    30721 gtaattgcaa acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct
    30781 tcatgatgtt tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa
    30841 gtagagaatt tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct
    30901 agacactgtg cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga
    30961 agtagcgtca ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt
    31021 ccgactgtta caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga
    31081 ttcgtggggt tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata
    31141 ctatctgctt cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga
    31201 tctttcatct gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt
    31261 gtcatgattg tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa
    31321 cgaaattcca caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt
    31381 tccatttcct gtagaatact tatttttgct atttccggtg tatctactaa tacttttact
    31441 tcagagtttt ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata
    31501 tactcatttc ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg
    31561 tttttgcgat cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg
    31621 ttttcgatga ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc
    31681 ccttctacaa gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc
    31741 actttgatca ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca
    31801 aattggacag tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca
    31861 tgatacttac gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca
    31921 gcgaatcttt ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct
    31981 gcagtattta caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct
    32041 gcggtcagct gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca
    32101 aaacgaggta tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga
    32161 ggatgatttt gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca
    32221 ctaacttcat aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc
    32281 ttggtattcc attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag
    32341 ccatccgttt cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct
    32401 ttttgaactg cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac
    32461 agttcatttg cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca
    32521 ccattcatca tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc
    32581 ttccaaaagg caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa
    32641 ttggcaaata gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag
    32701 tattgggaag aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca
    32761 ccacggccaa acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc
    32821 atatttccaa atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt
    32881 tcttccatgc caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct
    32941 tgcaagatat aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc
    33001 tgtctttttt ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa
    33061 tgaaaactgt tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca
    33121 atcagtcgca tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga
    33181 gaaatgatat atactttctt tttcatttac gatacctcct acttttctac tctaatatca
    33241 aagtaatcca tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta
    33301 taattttcag gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt
    33361 gctacaagta aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc
    33421 atagctaatg caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt
    33481 gcgtactttc cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc
    33541 agataatctt cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc
    33601 acattactgt catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc
    33661 gtttgccctt tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc
    33721 ttcaatttct gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct
    33781 tccacataac ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg
    33841 caagtatcat cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca
    33901 cctcgcccgt cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa
    33961 ggagagtgtt catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca
    34021 ataaaagatt gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac
    34081 tgtattgggt agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt
    34141 tttgtatgat ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat
    34201 ggatcgatat tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat
    34261 tcctcatctt cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac
    34321 cacatcgctg gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact
    34381 gttgtcaaca gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata
    34441 tccccacatt tttgtgtgat atcttccata aatttctgca ccgaatttgg tatatcttta
    34501 taagccacta ataaaacctt ctttctattt gatatatctt taaagattat acttcataca
    34561 gccaattatg tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt
    34621 attatttgaa tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac
    34681 aatatttaat gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact
    34741 accaactgaa aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc
    34801 attgactgaa ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt
    34861 taaatccgct tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt
    34921 tcttcttcca tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt
    34981 gatgcaagat aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac
    35041 agcaaaagag ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca
    35101 acatcttgac ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa
    35161 aaaaatctat gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct
    35221 tgctgcctct tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca
    35281 gactcatcca caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc
    35341 tggtttgact ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc
    35401 ttatatcact aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca
    35461 gaccatgaat ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg
    35521 atttgatgat atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga
    35581 ttttgaacag ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga
    35641 tcgaccatcc gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa
    35701 ataaaatgaa tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct
    35761 ctaatgggaa ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc
    35821 aaactacgga tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct
    35881 accgtcttac ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc
    35941 cgatcaatgg aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag
    36001 aagaaagtat attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt
    36061 ctacattgat acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca
    36121 gcggtttact tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag
    36181 tggaaggaaa aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta
    36241 tattgagatt tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg
    36301 actcgatccc gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt
    36361 ttatcagctc ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga
    36421 cttaccttgc tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac
    36481 accatgatca acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc
    36541 cacaaacatt ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc
    36601 gatctataaa acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg
    36661 tttatcctct ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt
    36721 tgaacagcta tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac
    36781 ttatgcctgg gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac
    36841 gagacttgat gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac
    36901 atccaaatta tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc
    36961 actaccacga atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc
    37021 aagttgccaa ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga
    37081 actatcaaaa tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca
    37141 agttcagaga accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt
    37201 ggcaaagcag ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca
    37261 gtgagagata taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag
    37321 gaggatatgg ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat
    37381 tagctatttc aaaccagcca agttttcact atccttactt gttcagttat ataggacaac
    37441 ctgaaatggc acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa
    37501 tgggttaccc tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc
    37561 tgggatttta tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg
    37621 acaaggctgt tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc
    37681 ggccgcagca acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat
    37741 attttaccca tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc
    37801 ctcaccctaa gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac
    37861 aagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat
    37921 cctcatattt ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt
    37981 attgagaggt tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata
    38041 gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
    38101 tagtggagag gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa
    38161 tggctttcca catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc
    38221 gtttatcgag aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt
    38281 agatttctag acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc
    38341 tccactgttt tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga
    38401 gaaatacgtg gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact
    38461 gtgcaaaagc agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact
    38521 ttttttcgtt tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc
    38581 tgacacttct ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt
    38641 ttccacattg tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag
    38701 ctgctgaagt tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc
    38761 ctcatcttcc agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata
    38821 tcgtatatct tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat
    38881 tttttgagcg acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat
    38941 ggtttgatct tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata
    39001 aaattgatgc aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa
    39061 agaatctgtc tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac
    39121 aaaacaacag aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc
    39181 tccgtaattt cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag
    39241 agtatcatga gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg
    39301 tcctattatt tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa
    39361 cagttcttga tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt
    39421 gattttcttg aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac
    39481 ggcgcctaat tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat
    39541 aaattcaaaa ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc
    39601 tggcattgtc acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc
    39661 ttctttggca ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat
    39721 cttttttaac ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct
    39781 catccctcct tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac
    39841 atataataac tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata
    39901 gaaccgtgaa gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt
    39961 tcagtcatcc cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag
    40021 actttgacac ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt
    40081 tcaactaatg gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc
    40141 ataaaatgat aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg
    40201 caaaagtcca gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc
    40261 aaagcggaaa acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac
    40321 attcggatat attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc
    40381 cgcatatgtg cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg
    40441 atgctatcca acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt
    40501 gttatgtcga tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg
    40561 atagatactt gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg
    40621 tctaaaataa tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca
    40681 ctttttttat ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca
    40741 aaattgtttt tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg
    40801 atgatcattt cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat
    40861 agtcgatttg tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt
    40921 tctaaaatca tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct
    40981 cctccttgtg tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt
    41041 tttatttccc cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac
    41101 acgatatata tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg
    41161 aaagaaacta attcatcggt actgttttgc tgttcgtata catacatcag atactgatct
    41221 atgggttttg ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg
    41281 tttttgatga tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg
    41341 gcatcacttg tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa
    41401 ataacggtag cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga
    41461 tttagtaagg ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt
    41521 atctaattct tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat
    41581 gacaccaaac aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc
    41641 aataattatt tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag
    41701 cagattagga acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc
    41761 aaataggcag agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt
    41821 gatttgaaca gataaatata aattgtaact caataaagca gtaccagata aaaataaact
    41881 aaatagcaga ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt
    41941 gatttcttta tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc
    42001 acctaatcca aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt
    42061 tataatgacc cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc
    42121 tccaaacatt aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt
    42181 gacctgatta ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag
    42241 cgaataccga gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt
    42301 agtttcgagt agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta
    42361 gcttaatacc gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac
    42421 gtcttttgtc acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat
    42481 tgtttttgca tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat
    42541 ttcggtaatg tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc
    42601 atgacattag aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct
    42661 aaaatcggtg aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc
    42721 gtaatagact cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt
    42781 gtatttggct gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc
    42841 catgcttctc cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc
    42901 agccctagaa gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt
    42961 gccatttgtg cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct
    43021 tgttttgctg catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca
    43081 cgcattagcc aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt
    43141 ggaatgagtc cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca
    43201 ttatcgtatt ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac
    43261 gtattcccta aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa
    43321 gctgccgtgt ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa
    43381 gattggattc catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt
    43441 acttgttgag caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga
    43501 tttcctttaa tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct
    43561 aattcagtca aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag
    43621 gcgatatcat aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc
    43681 cagccaatgt aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct
    43741 acttccatca attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg
    43801 tccgaattgc tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt
    43861 cccaacaaca acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt
    43921 cctcctaatt ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag
    43981 acctttgaca aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat
    44041 gactacgatc gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg
    44101 gcttcctgct cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag
    44161 atactgtagt ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt
    44221 ccagtaaccc aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa
    44281 aacgatctga acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat
    44341 cgaatcagag accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac
    44401 agccattggc aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac
    44461 aagataattg gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa
    44521 aaaacgacgg aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt
    44581 gctattgatc agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat
    44641 tttatcctgc atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca
    44701 aaaactgtac ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa
    44761 tataaatggc aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt
    44821 agccgtctta ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt
    44881 cctccttaga ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc
    44941 aacaagacaa agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct
    45001 cctgtggatg tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat
    45061 gcaccggaat tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct
    45121 acggctaaaa tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg
    45181 atctgctgcc atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt
    45241 cccataacag atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg
    45301 aacaccaaga taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca
    45361 tgtccagtga tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag
    45421 taactgataa tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta
    45481 acgagtcgtt tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga
    45541 ttcaaaagga taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga
    45601 tccgaagaaa ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta
    45661 gccaagaacc catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca
    45721 ggtatgtaaa agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct
    45781 ttataacgcc atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa
    45841 cccctttcga ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca
    45901 aagtataggg aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga
    45961 gtattagaga aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac
    46021 cgagggtcag ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga
    46081 gtattaggga gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg
    46141 taacaaaagt cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct
    46201 acggaaataa gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct
    46261 tttcagatgg cgctacaact actctgctta ttcttttagc tatccattca attatttttc
    46321 tctcacttgt tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt
    46381 aggcagccaa aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc
    46441 tttgaccatt cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga
    46501 agtttctgtc tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc
    46561 gccatcaata atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct
    46621 aacctcagct agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa
    46681 caccccgtca ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg
    46741 aaaaagatct tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt
    46801 atcctgagta gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg
    46861 atacgtaatg atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt
    46921 atcgcttttc accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac
    46981 ttctttgcgg ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc
    47041 ccatttcaaa agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg
    47101 tcgtaaacgc gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa
    47161 ataaccatac actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa
    47221 tttgctatct tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag
    47281 cataatcaag gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa
    47341 gcgggctact tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat
    47401 tgtcgccaat aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag
    47461 tttcactaga aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg
    47521 cagcatgttg gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat
    47581 cagtacatta cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag
    47641 taacataaca ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct
    47701 tgtcaatttt gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa
    47761 cccagtagac gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt
    47821 ggcactaaaa atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga
    47881 catgatcttc ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac
    47941 aataataaac ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt
    48001 tattttgttt tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa
    48061 atacaaaagg acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt
    48121 gaccgccgtc acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat
    48181 ataaaaaata cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg
    48241 attgccttgc aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact
    48301 caaagaacgc atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg
    48361 agaggcgatg tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc
    48421 acggataaat aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg
    48481 ttttgcaatc gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt
    48541 gtatcccata ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca
    48601 gggaatgata tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc
    48661 agagcctcgt gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt
    48721 atccatcggt cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca
    48781 gaaactggca atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt
    48841 tcgttttttt ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat
    48901 atcaatgaca caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac
    48961 agttggattg aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat
    49021 cggacattta gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa
    49081 tcttatgatg ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt
    49141 agcgggaagt ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc
    49201 ctcacatttc ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt
    49261 gtacacagtc ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt
    49321 ttttcggctt ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa
    49381 ttattatgtt tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc
    49441 attgtttatg aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg
    49501 gattttgtca tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga
    49561 aattgaataa agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac
    49621 tattaaaaga aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac
    49681 cagaaaaagc tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt
    49741 tgtttttctg taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg
    49801 gtattcaata ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa
    49861 cggatatccg taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata
    49921 aattgaaagt gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa
    49981 aagcaatctt ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa
    50041 cgttagatgg caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat
    50101 atcgtatgat gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt
    50161 cacaagctta caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga
    50221 atatctcgcc tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt
    50281 gcaagcgaca attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt
    50341 ttgatttact tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt
    50401 cggaagaaag caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat
    50461 cttctcatga agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag
    50521 gattcaacca agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca
    50581 gtcaagatgc acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga
    50641 tccaatccaa tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa
    50701 cattgctgaa atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca
    50761 gcccaggaaa caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag
    50821 ctgacatcgc ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg
    50881 aagaaatcaa tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc
    50941 ctgaagcgat tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg
    51001 gaaaaggcgt ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt
    51061 atgcaatcgt gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat
    51121 ttctaagaaa aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt
    51181 ttaacttttc actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat
    51241 catagaattt gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta
    51301 acacagcagc tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag
    51361 gccacggcat ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga
    51421 gtgtagcaga agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga
    51481 ttggcatccc gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt
    51541 ttcctaacac tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta
    51601 aagtcgcacc tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat
    51661 aatttgcgcc ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag
    51721 tgatgatatt cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca
    51781 ccatgacacc aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca
    51841 ttttgaagat atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg
    51901 caatgacaaa tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat
    51961 ctggcatttt tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa
    52021 tcgacataat aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca
    52081 tcctaatacc atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac
    52141 catcagtcat gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc
    52201 ccgtgagcgg attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag
    52261 caaacacaat ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt
    52321 acaagtcact aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta
    52381 atggcaaaat atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca
    52441 tccccgctgc catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca
    52501 tcaggtattt ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt
    52561 ttcatattgt ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg
    52621 atactgtata aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg
    52681 tcctccattg ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac
    52741 tggaatcact aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac
    52801 gttcgtttgg tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa
    52861 aatcagaatc atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca
    52921 ttgcatgttc atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa
    52981 atacatgttt ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc
    53041 ctgcacaatg atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc
    53101 aacttccaat aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc
    53161 catttctatt tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc
    53221 atgaagaatc tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt
    53281 acgcatcgag cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat
    53341 atcaaaagaa gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc
    53401 ttattcgatc agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat
    53461 ttcctgctgt acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat
    53521 tccttcattt tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg
    53581 atcccactgc atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg
    53641 aacagcggga tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg
    53701 ttgctggatc tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt
    53761 ttgcagcaaa tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa
    53821 tttttcagac aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat
    53881 cggtctatct gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac
    53941 atcatcttca ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga
    54001 aagatcaata gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata
    54061 atagcctttt acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt
    54121 taatagttgg gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc
    54181 agctctttct ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc
    54241 attgatggta tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa
    54301 gactttggga ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg
    54361 gctcaatcga atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc
    54421 ctctactaat gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt
    54481 tgatagttcc tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt
    54541 caaataagca atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac
    54601 gatccgctgc gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc
    54661 cttgatttca aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt
    54721 ctgtatgata aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat
    54781 gactagctct tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa
    54841 tgaatttcca taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc
    54901 ttccccttcg atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat
    54961 caatcgctcc ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc
    55021 ttctgccaaa tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata
    55081 cttttgtcga tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat
    55141 ttcttgccga ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc
    55201 ataacctggt ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg
    55261 caagtaatta cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt
    55321 gacatactcc ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat
    55381 tatcatccac tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg
    55441 cctgtaggga ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat
    55501 tctcctaatt ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa
    55561 tcaaaatcac tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt
    55621 acctcttctc ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac
    55681 attcctgccg cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta
    55741 taaaccaagc atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg
    55801 gaaaaaatgt gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag
    55861 aattttttca ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa
    55921 tggacaagcc agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg
    55981 tgcagaagaa ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct
    56041 tttactgatc gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat
    56101 gatggctcaa ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt
    56161 cactgattta ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc
    56221 ttcacttttt ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct
    56281 tatttttcgg ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag
    56341 gatattctca aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat
    56401 tgccaaagca ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa
    56461 agctagacca cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa
    56521 taaaacacat ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat
    56581 cgacatcaat ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg
    56641 ctgaaaaggg acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag
    56701 catccaaatt ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt
    56761 gtctttgttc ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa
    56821 aaataataag ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga
    56881 ataaacaata aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact
    56941 agcggttgcc attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga
    57001 ccatttgatc agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc
    57061 tatgatcgaa tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca
    57121 gaataaaacc acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat
    57181 aaaacaaatg gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat
    57241 gcacttttct tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag
    57301 ttgtagagac tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac
    57361 agtcatctat gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt
    57421 caactatttt tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa
    57481 tcaccacaaa ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa
    57541 ttctgagatc aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga
    57601 agaaaaaaac attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt
    57661 gtggttctgc tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg
    57721 aaaccattgt ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc
    57781 agcgctatac ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc
    57841 caaggcactc gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag
    57901 tgtcgttatt ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat
    57961 tgaaagagtt gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga
    58021 gggttgtgaa tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga
    58081 tggcgagaca gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca
    58141 aactatttcc ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac
    58201 gccacctact ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga
    58261 ttacttggtt tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag
    58321 ctttccgaga caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact
    58381 agagaaaaaa ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca
    58441 ataaacttga gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt
    58501 tttgtatatt ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca
    58561 gcacaaaatt gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa
    58621 tatttgtttg tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt
    58681 gattttaaaa actatgctta ttcaattttt tattttagct catatatttc gtttctttct
    58741 aaattttata ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat
    58801 gatggtttct ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct
    58861 tatatctgag ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg
    58921 ttctttttcg atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg
    58981 agtttctacc agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc
    59041 tcctgtggtt agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc
    59101 tccttgcagg acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt
    59161 aagtcgattt tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc
    59221 gattggtgtc gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac
    59281 tcctggtgct aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg
    59341 cagaacggtt ccattggcat cttgtaactc aaaaacagct tcttgcagga cttccccgct
    59401 ttggtcatcg atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa
    59461 ttctaccacc gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc
    59521 ataccccgtt gg
//
LOCUS       DARPZJ010000013        56387 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.013, whole genome shotgun sequence.
ACCESSION   DARPZJ010000013 DARPZJ010000000
VERSION     DARPZJ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.013"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            330..1175
                     /locus_tag="SLE23_000999"
     CDS             330..1175
                     /locus_tag="SLE23_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8467917.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="SLE23_001000"
     CDS             1456..2676
                     /locus_tag="SLE23_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HEI8467918.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="SLE23_001001"
     CDS             2673..5393
                     /locus_tag="SLE23_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8467919.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="SLE23_001002"
     CDS             5377..6321
                     /locus_tag="SLE23_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8467920.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="SLE23_001003"
     CDS             complement(6390..7400)
                     /locus_tag="SLE23_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8467921.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="SLE23_001004"
     CDS             complement(7580..7924)
                     /locus_tag="SLE23_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEI8467922.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="SLE23_001005"
     CDS             complement(7917..8351)
                     /locus_tag="SLE23_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEI8467923.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="SLE23_001006"
     CDS             8489..9226
                     /locus_tag="SLE23_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8467924.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="SLE23_001007"
     CDS             9219..10430
                     /locus_tag="SLE23_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8467925.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="SLE23_001008"
     CDS             10634..11416
                     /locus_tag="SLE23_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEI8467926.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="SLE23_001009"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="SLE23_001009"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEI8467927.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="SLE23_001010"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="SLE23_001010"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HEI8467928.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKEHLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="SLE23_001011"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="SLE23_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEI8467929.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="SLE23_001012"
     CDS             15018..16067
                     /locus_tag="SLE23_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HEI8467930.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="SLE23_001013"
     CDS             16064..16342
                     /locus_tag="SLE23_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEI8467931.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="SLE23_001014"
     CDS             16317..16787
                     /locus_tag="SLE23_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEI8467932.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="SLE23_001015"
     CDS             16804..17106
                     /locus_tag="SLE23_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467933.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="SLE23_001016"
     CDS             17123..17494
                     /locus_tag="SLE23_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HEI8467934.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="SLE23_001017"
     CDS             17466..17825
                     /locus_tag="SLE23_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467935.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="SLE23_001018"
     CDS             17997..19004
                     /locus_tag="SLE23_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8467936.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="SLE23_001019"
     CDS             19029..20213
                     /locus_tag="SLE23_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEI8467937.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="SLE23_001020"
     CDS             complement(20650..22233)
                     /locus_tag="SLE23_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8467938.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="SLE23_001021"
     CDS             complement(22811..22954)
                     /locus_tag="SLE23_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEI8467939.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="SLE23_001022"
     CDS             complement(23177..23656)
                     /locus_tag="SLE23_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8467940.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="SLE23_001023"
     CDS             complement(23729..24013)
                     /locus_tag="SLE23_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467941.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="SLE23_001024"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="SLE23_001024"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="SLE23_001025"
     CDS             complement(24357..25643)
                     /locus_tag="SLE23_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEI8467942.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKSAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="SLE23_001026"
     CDS             25781..26452
                     /locus_tag="SLE23_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HEI8467943.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="SLE23_001027"
     CDS             26418..26906
                     /locus_tag="SLE23_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEI8467944.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="SLE23_001028"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="SLE23_001028"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEI8467945.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="SLE23_001029"
     CDS             27867..28631
                     /locus_tag="SLE23_001029"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEI8467946.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="SLE23_001030"
     CDS             28864..31077
                     /locus_tag="SLE23_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEI8467947.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="SLE23_001031"
     CDS             31088..31534
                     /locus_tag="SLE23_001031"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEI8467948.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="SLE23_001032"
     CDS             31705..32964
                     /locus_tag="SLE23_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HEI8467949.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="SLE23_001033"
     CDS             complement(33053..34000)
                     /locus_tag="SLE23_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8467950.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="SLE23_001034"
     CDS             34394..35686
                     /locus_tag="SLE23_001034"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEI8467951.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="SLE23_001035"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="SLE23_001035"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEI8467952.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="SLE23_001036"
     CDS             37579..38454
                     /locus_tag="SLE23_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8467953.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="SLE23_001037"
     CDS             38720..40603
                     /locus_tag="SLE23_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEI8467954.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="SLE23_001038"
     CDS             complement(40678..40962)
                     /locus_tag="SLE23_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEI8467955.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="SLE23_001039"
     CDS             complement(40952..41686)
                     /locus_tag="SLE23_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEI8467956.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="SLE23_001040"
     CDS             41815..42438
                     /locus_tag="SLE23_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEI8467957.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="SLE23_001041"
     CDS             42630..43751
                     /locus_tag="SLE23_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HEI8467958.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="SLE23_001042"
     CDS             43758..46886
                     /locus_tag="SLE23_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEI8467959.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="SLE23_001043"
     CDS             46905..50099
                     /locus_tag="SLE23_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEI8467960.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="SLE23_001044"
     CDS             complement(50245..50952)
                     /locus_tag="SLE23_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8467961.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="SLE23_001045"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="SLE23_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEI8467962.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="SLE23_001046"
     CDS             52447..53100
                     /locus_tag="SLE23_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEI8467963.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="SLE23_001047"
     CDS             53326..54324
                     /locus_tag="SLE23_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEI8467964.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="SLE23_001048"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="SLE23_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEI8467965.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18554 a         9728 c        11686 g        16419 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaatg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcac tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttttt
//
LOCUS       DARPZJ010000014        52885 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.014, whole genome shotgun sequence.
ACCESSION   DARPZJ010000014 DARPZJ010000000
VERSION     DARPZJ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.014"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="SLE23_001049"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="SLE23_001049"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEI8467966.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="SLE23_001050"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="SLE23_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEI8467967.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="SLE23_001051"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="SLE23_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEI8467968.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="SLE23_001052"
     CDS             complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="SLE23_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEI8467969.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="SLE23_001053"
     CDS             complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="SLE23_001053"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEI8467970.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="SLE23_001054"
     CDS             complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="SLE23_001054"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEI8467971.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8054..8524)
                     /locus_tag="SLE23_001055"
     CDS             complement(8054..8524)
                     /locus_tag="SLE23_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HEI8467972.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8570..8995)
                     /locus_tag="SLE23_001056"
     CDS             complement(8570..8995)
                     /locus_tag="SLE23_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEI8467973.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9062..9331)
                     /locus_tag="SLE23_001057"
     CDS             complement(9062..9331)
                     /locus_tag="SLE23_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEI8467974.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9342..10937)
                     /locus_tag="SLE23_001058"
     CDS             complement(9342..10937)
                     /locus_tag="SLE23_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8467975.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="SLE23_001059"
     CDS             complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="SLE23_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEI8467976.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14490..15050)
                     /locus_tag="SLE23_001060"
     CDS             complement(14490..15050)
                     /locus_tag="SLE23_001060"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEI8467977.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15403..16377
                     /locus_tag="SLE23_001061"
     CDS             15403..16377
                     /locus_tag="SLE23_001061"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEI8467978.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16547..17947
                     /locus_tag="SLE23_001062"
     CDS             16547..17947
                     /locus_tag="SLE23_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HEI8467979.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVVLETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18025..18747)
                     /locus_tag="SLE23_001063"
     CDS             complement(18025..18747)
                     /locus_tag="SLE23_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8467980.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18826..19332)
                     /locus_tag="SLE23_001064"
     CDS             complement(18826..19332)
                     /locus_tag="SLE23_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEI8467981.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19455..21254
                     /locus_tag="SLE23_001065"
     CDS             19455..21254
                     /locus_tag="SLE23_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HEI8467982.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21322..22896)
                     /locus_tag="SLE23_001066"
     CDS             complement(21322..22896)
                     /locus_tag="SLE23_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEI8467983.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="SLE23_001067"
     CDS             complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="SLE23_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEI8467984.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="SLE23_001068"
     CDS             complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="SLE23_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEI8467985.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24673..25311)
                     /locus_tag="SLE23_001069"
     CDS             complement(24673..25311)
                     /locus_tag="SLE23_001069"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEI8467986.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25312..25962)
                     /locus_tag="SLE23_001070"
     CDS             complement(25312..25962)
                     /locus_tag="SLE23_001070"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEI8467987.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="SLE23_001071"
     CDS             complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="SLE23_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEI8467988.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="SLE23_001072"
     CDS             complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="SLE23_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEI8467989.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEKMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29105..29845)
                     /locus_tag="SLE23_001073"
     CDS             complement(29105..29845)
                     /locus_tag="SLE23_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEI8467990.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="SLE23_001074"
     CDS             complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="SLE23_001074"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEI8467991.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31216..32154)
                     /locus_tag="SLE23_001075"
     CDS             complement(31216..32154)
                     /locus_tag="SLE23_001075"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEI8467992.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32147..32638)
                     /gene="def"
                     /locus_tag="SLE23_001076"
     CDS             complement(32147..32638)
                     /gene="def"
                     /locus_tag="SLE23_001076"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEI8467993.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32653..35061)
                     /gene="priA"
                     /locus_tag="SLE23_001077"
     CDS             complement(32653..35061)
                     /gene="priA"
                     /locus_tag="SLE23_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEI8467994.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35314..35619)
                     /locus_tag="SLE23_001078"
     CDS             complement(35314..35619)
                     /locus_tag="SLE23_001078"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEI8467995.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="SLE23_001079"
     CDS             complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="SLE23_001079"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEI8467996.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36725..37009)
                     /locus_tag="SLE23_001080"
     CDS             complement(36725..37009)
                     /locus_tag="SLE23_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8467997.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37027..37917)
                     /locus_tag="SLE23_001081"
     CDS             complement(37027..37917)
                     /locus_tag="SLE23_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HEI8467998.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37937..38155)
                     /locus_tag="SLE23_001082"
     CDS             complement(37937..38155)
                     /locus_tag="SLE23_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEI8467999.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38125..39825)
                     /locus_tag="SLE23_001083"
     CDS             complement(38125..39825)
                     /locus_tag="SLE23_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HEI8468000.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40091..40864
                     /locus_tag="SLE23_001084"
     CDS             40091..40864
                     /locus_tag="SLE23_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468001.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40945..41514)
                     /gene="thiT"
                     /locus_tag="SLE23_001085"
     CDS             complement(40945..41514)
                     /gene="thiT"
                     /locus_tag="SLE23_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEI8468002.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41580..41682)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41688..42659)
                     /locus_tag="SLE23_001086"
     CDS             complement(41688..42659)
                     /locus_tag="SLE23_001086"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEI8468003.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42753..44126)
                     /gene="glmU"
                     /locus_tag="SLE23_001087"
     CDS             complement(42753..44126)
                     /gene="glmU"
                     /locus_tag="SLE23_001087"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEI8468004.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44629..45447)
                     /gene="purR"
                     /locus_tag="SLE23_001088"
     CDS             complement(44629..45447)
                     /gene="purR"
                     /locus_tag="SLE23_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEI8468005.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45614..46438)
                     /locus_tag="SLE23_001089"
     CDS             complement(45614..46438)
                     /locus_tag="SLE23_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEI8468006.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46411..47091)
                     /locus_tag="SLE23_001090"
     CDS             complement(46411..47091)
                     /locus_tag="SLE23_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEI8468007.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47114..48052)
                     /locus_tag="SLE23_001091"
     CDS             complement(47114..48052)
                     /locus_tag="SLE23_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEI8468008.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48297..49160)
                     /locus_tag="SLE23_001092"
     CDS             complement(48297..49160)
                     /locus_tag="SLE23_001092"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEI8468009.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49302..51875)
                     /gene="mprF"
                     /locus_tag="SLE23_001093"
     CDS             complement(49302..51875)
                     /gene="mprF"
                     /locus_tag="SLE23_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEI8468010.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52016..52822
                     /gene="proC"
                     /locus_tag="SLE23_001094"
     CDS             52016..52822
                     /gene="proC"
                     /locus_tag="SLE23_001094"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEI8468011.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT        14662 a        11478 c         9505 g        17240 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agttttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaag
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggga
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca
     5401 tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata
     5461 taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg
     5521 ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg
     5581 tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt
     5641 attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc
     5701 ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat
     5761 taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg
     5821 catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta
     5881 atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca
     5941 gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata
     6001 tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac
     6061 ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt
     6121 gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct
     6181 gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt
     6241 gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa
     6301 atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc
     6361 ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc
     6421 tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt
     6481 ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag
     6541 tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta
     6601 tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact
     6661 ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg
     6721 tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga
     6781 gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga
     6841 ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg
     6901 tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct
     6961 cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac
     7021 tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct
     7081 ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt
     7141 tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc
     7201 atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt
     7261 ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt
     7321 ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct
     7381 gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta
     7441 gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt
     7501 ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat
     7561 tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct
     7621 atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca
     7681 caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg
     7741 tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa
     7801 accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat
     7861 ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct
     7921 ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt
     7981 ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat
     8041 tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc
     8101 gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga
     8161 agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat
     8221 ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct tctccagatt
     8281 cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg
     8341 aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat
     8401 agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa
     8461 acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg
     8521 acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag
     8581 ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata
     8641 taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta
     8701 catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga
     8761 cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca
     8821 tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg
     8881 cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact
     8941 ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga
     9001 ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa
     9061 tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat
     9121 cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa
     9181 actggacttt caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt
     9241 tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc
     9301 gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta
     9361 tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga
     9421 cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg
     9481 acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa
     9541 tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc
     9601 cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc
     9661 acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga
     9721 aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga
     9781 aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg
     9841 gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg
     9901 atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat
     9961 ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga
    10021 gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact
    10081 aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg
    10141 taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat
    10201 ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac
    10261 ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca
    10321 tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc
    10381 gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc
    10441 acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat
    10501 cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa
    10561 actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta
    10621 aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt
    10681 tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac
    10741 tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga
    10801 taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt
    10861 aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc
    10921 atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca
    10981 acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga
    11041 tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg
    11101 ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag
    11161 taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca
    11221 ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt
    11281 cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt
    11341 tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga
    11401 caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag
    11461 aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat
    11521 gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct
    11581 tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt
    11641 cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc
    11701 ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga
    11761 acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa
    11821 catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt
    11881 gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt
    11941 gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc
    12001 gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat
    12061 aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat
    12121 gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact
    12181 gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac
    12241 ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa
    12301 cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac
    12361 ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct
    12421 gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt
    12481 taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc
    12541 gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt
    12601 catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc
    12661 caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga
    12721 tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct
    12781 tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag
    12841 taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa
    12901 cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga
    12961 caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg
    13021 tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta
    13081 ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct
    13141 gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca
    13201 tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt
    13261 gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca
    13321 tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga
    13381 agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg
    13441 aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg
    13501 cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta
    13561 aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt
    13621 agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt
    13681 aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca
    13741 ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg
    13801 ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat
    13861 accgcataga atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta
    13921 acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct
    13981 cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat
    14041 caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt
    14101 gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg
    14161 ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt
    14221 catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta
    14281 actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa
    14341 acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag
    14401 gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt
    14461 gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac
    14521 gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc
    14581 aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct
    14641 tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata
    14701 atacttttga taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc
    14761 actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa
    14821 gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa
    14881 aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg
    14941 aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt
    15001 gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc
    15061 cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg
    15121 agcttttttc ttttttatac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc
    15181 taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa
    15241 taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc
    15301 ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca
    15361 taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa
    15421 aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc
    15481 tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct
    15541 aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa
    15601 atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc
    15661 gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac
    15721 cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct
    15781 aacccagtag atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc
    15841 gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta
    15901 gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa
    15961 ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac
    16021 aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct
    16081 tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt
    16141 atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat
    16201 ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt
    16261 atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct
    16321 gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct
    16381 ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat
    16441 ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta
    16501 tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc
    16561 gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct
    16621 gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga
    16681 aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga
    16741 agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc
    16801 aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga
    16861 acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga
    16921 tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct
    16981 gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga
    17041 ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa
    17101 acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga
    17161 aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc
    17221 tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag
    17281 tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt
    17341 acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt
    17401 taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca
    17461 aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg
    17521 ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat
    17581 cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggtccttga
    17641 aacagatatc gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg
    17701 gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag
    17761 tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg
    17821 gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac
    17881 cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt
    17941 cttctaacaa aaataatata taaaaagaaa gcacccgtac gattggtaca ggtgctttct
    18001 ttttattatc taacaatgtg ctacttacat ttcagcagca gtaaagactt ctgaaacatc
    18061 atcatcgtct tctagcttat ctactagacg ttccaattgc tctttttgtt cctcatttaa
    18121 atcaatcgtc gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga actctttttc
    18181 caactcatct cgtacagcag caaaatcttc tggtgcagta taaatctcga atacttcagg
    18241 agaagtttgc agatcttctg cccccgcctc taatacatcc tcaaacatcg tctcttcatc
    18301 aacagtcaac ccatcgcgtt caatagcgat atatcctttg cggtcaaaca agtaactgac
    18361 tgaacccgtt tctcccagtg atccaccgtt tcgagtaaaa gctactcgga catttgtcgc
    18421 tgtccgatta cggttatctg tcaatgcatg gactaagatt cctactccac ccggaccata
    18481 tccttcatac gtgatttcat cgtaattcgt ttcatctacg gcactcgtag cctttttaat
    18541 cgcccgttcc acattgtcgt taggcatatt tgcagctttt gctttgtcca caacaagccg
    18601 caaagctgga ttcatagatg gatcaggacc gcctgcttta gctgccatat aaatttcacg
    18661 agaaagtttc tgaaagactt tccctcgttt tgcatcttgg gcattttttc ttccttggat
    18721 attatgccat ttactatgtc ctgacatgat ttttcctccc ttgttctttt gagaatacac
    18781 ttctattcta gtactatttc acaaaaaaac aaagccacag ccaatctata aacgcttctt
    18841 gaatgccgca aaaagcacac ataatatcac agcagtcaga gcaccgatcg aatccaacat
    18901 gacatcttgg aacataggtg ttcgtccacc ggtcatcatc tgatggaatt cgtccaaacc
    18961 tgcgtaccct gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa tttttagctt
    19021 ggggaaaaca cctaaaaaca agctgcctcc caaaataaaa taggtaccga aatgtgcgcc
    19081 cttccttaaa aagaactcta aaaatttggc gtagcccaga tggtcgatac tcaccatact
    19141 tccaccataa ttaaaacgta tacccgctaa tgtgtcttta aatggctgat taggcagcca
    19201 gctttctaat cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac tgtaaaataa
    19261 gattataacg actatcagtg cgattactaa ataaatattt ccgtttttca tttgtttttt
    19321 tgaagaattc ataagtcacc tctgtatttt atcttagact ttttttgaag aaacaacaat
    19381 cattttcata gagacttctt ccataaaaaa gtgctatact taattttgta ttacaatatg
    19441 aagggagttt tttcatgagt tattcattaa attggaatct agattctatt ttttccggag
    19501 gcagtcattc tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa atgaacgagt
    19561 attatcaccg cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag ttaaacgcta
    19621 ttcttcaatt gcaagaaacg attacgaatg gttttaccca atgcagcagc tatattactg
    19681 cattgctttc tgccaatgtc aatgattcag atgcaaaggt cttatcaggc aagctttacg
    19741 caatgctgcc tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt gcagaaatat
    19801 ctgacaatga ttggaatcag atgctttctc aatcttcgtt tgaaacaatt gcttttcgtt
    19861 taaacgagat tcgtcgtgat ggctcacaat tattatcaga agctgaagaa aacattataa
    19921 atacgctttc tttagatggt ctaaatgctt ggagcagtca ttatgatacg attgtagcca
    19981 gcatttcgat tcccttcgaa caagatggac aagtagtcga attatctgct ggacaagcct
    20041 tcaataagat gatgggcgat ccagatccaa aagtcagaga aacacttttc gcagcatggg
    20101 aagaagcctg gaaagaaaag gcacccctct tcacggatac tttgaatcat ttagatggtt
    20161 ttagactttc tgactatgaa cttcatggtg tcacagattt tctacaaaaa ccattagagt
    20221 acaatcggtt gaagaaagaa acattgtctg tcatgtggga tacaatccag aaaaacaaac
    20281 aaccccttgt taattacttg actagaaaag ctaatctttt cggtaaagaa aaaatggaat
    20341 ggcaagatca agatgcacct attattttag gcgatttgaa agaaaaaacc tttagttttg
    20401 acgaagcagc agcatttatt atcgaaaact ttaacaaatt cagtccaaaa atggctaaat
    20461 ttgcccaatc tgcttttgaa aagagctgga tcgaagcaga agatcgtcct gggaaacgtc
    20521 ctggtggtta ttgtactgag ttaccagaaa caaaagaatc aaggatcttt atgacctaca
    20581 gtaattctgt taatgaggtt gcgacacttg ctcatgaact aggacatgct ttccatagca
    20641 gcacgatgtg ggatttacct tctttaaatc gcgaatatgc catgaatgtc gcagaaacag
    20701 caagtacatt cgcagaactg atcgtagccg atgctacatt aaaagtcgca aaaacaaaag
    20761 aagaaaaaat caatttgcta gatacaaaac tgcaaaatgc tttagctatg ttcatgaata
    20821 tccattcccg attcattttt gaaaatcgat tctatgaagc acggcaagaa ggattagtct
    20881 cagaagataa gatcacagag atgatggttg aggcgcaaaa agaaggctat caaggagctt
    20941 tagctactta ccatccatat ttctgggctg caaaattgca tttctttatt gatgacgtac
    21001 cgttttataa cttcccatac acatttggct acctctttag tttgggcatc tatgcttacg
    21061 ccaaccaaaa gggagcaaat tttgaagaag aatatatcca tttactacgc gatactgcct
    21121 caatgacgac ggaagatctt gcgaagaaac atttgaatgt cgatcttacc caaccagatt
    21181 tttggcaagc aggtatcgac atggtgactg aagatatcca aacgttcatg gaattgacag
    21241 aagaatttat ctgatttcta ttttatcaca ataaaaaaag agttagtcca gaatgggcta
    21301 actctttttg attaatcatt cttacatgct gacagcaaag tcaggggcaa accattgaac
    21361 tgaaccaact tttacgcttt cgcctggttg aggagcatgg atatattgtc ctccgcctaa
    21421 agcaatcgct acgtggtaag ttccgccttg tgacccccag aataacaagt ctccagcttt
    21481 tgcttgagaa actgaaattt ttgttccagc tgattcttga ggaactgtcc aaccaccgat
    21541 gtcacgacca gttacttgca tgtaaacata gcgtgtgaac cctgagcagt caaagccact
    21601 tggatcttta ccgccccaaa catatggagt accaatatat ttgtaagctt ctgctacgat
    21661 tgctgcacca ttcacacttc cagaaggagc tggagcaggt gttacaggtt ttggttgttc
    21721 aggtgttggt gttggcgttg gagccggagt actacttcct gtgccgtttc ctgtatcaac
    21781 actttgatct gttgatggtg ttgtaggcgc aggtgttgtt gattcttctg ttgttgaaga
    21841 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcactgttg ttgattcttc
    21901 tgttgctgaa gattcaggcg ctgttgttga ttcttctgtt gctgaagatt caggcgctgt
    21961 tgattcttct gttgaagatt caggtgttgt tgattcttct gttgctgaag attgtgtagc
    22021 tgatgatgat tcttcagtca ttgaagattg tgtagctgat gattcttctg ttgctgagct
    22081 ttgtgcagta gatgaagctt gagtagcttg tgcttcagcc tctgcttgtt cgcgtgcttc
    22141 tttttcagct ttttcttgtg cagcttgttg acgagcttgt tctgctagac gttgttgttc
    22201 acgaatacga gcttgctctg cttcagcttc tgctttttga cggttcaagt cagctttctt
    22261 gtcttcagca gttgcttgtt cagcagctaa tgaagttttc agtacgttca aatcagcttg
    22321 tttagataaa agatcgcctt tttgagattc caaagcagct tggttttcag ctaattcttt
    22381 tagtttagca tcgttttcag cttttttgtc ttctacagct tttttatctt gtttttgttg
    22441 ttccatcaag tcgttgtttg cttttaccat cgttgtcatt gcttgaacgc gtccaatagc
    22501 atctgctaat gaatcagcat tcaatacagc atcgatgtag tttgagcttg tgttgcttac
    22561 ttgtgcttcg cgtgcttgtt tttggattgt atcttcacgt ttttcaatac gttcttgtaa
    22621 atctgcaatg tcttttacta attgtgcaga ttcttgacgc aatgtatcct gttttgctaa
    22681 taggtcttgt gcttgtgtgt tgatttcaga aacttggctt tctaaggcat cgatttgtga
    22741 ttgtgcatct gcttgttgat ttttcaagtc tgcaatcttt tgatcttgct gttgtatctg
    22801 agaatcaaaa tcgtccgccg cggcagcgat cggtgatgct acggcagtca aggtcattga
    22861 acataccatt actgctgata ttaaactctt tttcactctt cattcctccg actggcttaa
    22921 tttaataaat atctaaatat atttaagtct ttcttaacga tataaaaatt gtaccatagc
    22981 agtgtgtcaa cgatataata gttatgttac aaaaatgttt caaaacaact tttaaaaatg
    23041 acaaaactgt tcgtttcaga aaatgatcat gaaaaagccg cgttaagtct agcatttctt
    23101 aagataacaa cgattctttt tcgctttcga cctaaaaata aaaaaagaaa ttattcatca
    23161 ctgaataatt tcttaaaggg aaaaatgaat aatacaaata taatcatgtt caacagcagt
    23221 gtaggtccta aaaaccttgt aataaaatac gtgttattta ctactgctaa tttaaaaatc
    23281 aactggacca ccatcgtaaa caattcataa cccgtgacaa agatgatcat actgaaaaat
    23341 tcagtaaaga tgttgacatg gataacgtct ttcattacat acatcaacca tacaattaaa
    23401 gggagagcta ctgcatagat accgataacg ccaatatagt aagcgtcata gatagccccg
    23461 agaacaatcg tggtaatcag taaataacgt ttttcaaacg ccatactgca acataataat
    23521 gccaatatca gaaagtgggc atttgacata taggtgcctt tcgaccactc ccctagcatt
    23581 cttgttaaat gaccatctat caacatcaaa aagaacaaaa cgattggcag atagtacttc
    23641 attgtttctt tcttcaacat ggactaatcc tccgctagcc gttggacaat cgtcacaact
    23701 gacacgtcat acatttctgc ataaggtttc acataaactt cccgatccag cccataacta
    23761 tctggtttcg ttttaataac cgtaccgatc ggcaagttag ctggagaatt ccctccaaga
    23821 ccggatgtct ggacaacatc cccttctttg atatccgtat caccagttaa ttgggtcacc
    23881 actaaggcat ggagcttttc atcatagttt ttaagcaaac caaacgcttc gccattagcc
    23941 gaagataccc gtactggaaa atgattggag ctttcattag aggatgacag taattcgatt
    24001 ttagacgaag ccgtattgac ctcgatcact cggccaatca atcctttttg cgacatgact
    24061 gccatatttg cttcgatacc gtctttagaa cccttgtcta cgatcagcat gtcctgccaa
    24121 ctgtcaggcg aacgagtaat gacatttgcc gttacttttt cgtaactagt cagcgtctga
    24181 ttcaactcaa gttctttttt caacgcttcg atttctctct cgtaattctt gttttgctgt
    24241 gaaacgtcat catagctatc gattttttct tttagccgct cattttcggc ataagttgaa
    24301 aaaagattat ggacagaatc tactccattt cgtacccacc gtactggggc agagattgtt
    24361 ttatcaacca ttgcaacact gtcattaacg atggattgga agaaattggg ctttccttca
    24421 ttcgctcgct gcgcagcggt cacacttagt atcgtcacca cgatgataac aataaccaag
    24481 gtaataataa tatttttatt aggattgaac ttcttcacaa agacacctcg aattaattag
    24541 actcttgtgt tcaattttat cactaaatgc cgtgaaacaa aaggtaagtt gctcctctta
    24601 agcttttttt tagcaaataa tagattctgt catttttagc ctgaaagaca aattttttta
    24661 tttgtttatg gatcaatctt tgctttgaat aactgcaatc ataccatctg aaaaagaaaa
    24721 ttctgcggta tctgaaagaa attcgttact tgcataagat gtcggatatt ctacttcttt
    24781 attttccaat acatacttgc tgccttttaa tgtaagattc gagacgggag tcaagcagca
    24841 ataagctaaa tacttcatat ctggtatctg tcttactata tgctctccag gcaaataata
    24901 agacaaataa ttttgacaat ctctgataat aagctgatgg gcaaagggtt tgaagcgagg
    24961 ttccatacct aaccagagat tggctaaaag atgatccaat cttccgcccg tagctccaat
    25021 caaagtgact tccgcttgcg ggtaacgttc aaatgttttt aagataccta actgtgtatc
    25081 tgtatcgtct ttttctgcag gggaacgggt atactctttg gcttttgcaa atacttcctt
    25141 ctgctcttcg ttcgacaatg aatcaaaatc acccactgcc agatctactg ggtagcctgc
    25201 ttgaagcagg tacagcgcac cacggtctat cccgacatag gcatcgtatt tggacagcag
    25261 agactgcggc cagttttgcg gattacctcc agcagctaat aaaattttca tttagtctaa
    25321 tgcctctttt aatcgttcga tttgtccgac tggattttcg gctccataga tatatgatcc
    25381 tgcaacgaag acatccgccc ctgcatcttt acagattttt gctgtttctg gaacgattcc
    25441 gccatctact tcgattgcat aagtccaatt gttctctcta cgtagatcag cgagttccgt
    25501 aattttttct actgtttctt caataaagct ttgtccgccg aacccaggat tgacagtcat
    25561 gactagtact tgatcagcca aaggcaaaac atgtttgatc atggagactg gtgttcctgg
    25621 attgataact actccagctt taactcctaa gctttttgtc atttgaagtg cccgatgaat
    25681 atgaggagtt gcttcgacgt ggacagtaat gatatctgct ccagcttttg caaatgctgg
    25741 aatgtagttt tctggatcaa cgatcatcag atggacgtct aacggtaatt tagtaacagg
    25801 acggattgcc tgaacaatat ttggccctaa tgtgatattt gggacaaatt ggccatccat
    25861 tacatctacg tggatgtaat ctgcgcctcc tttttccact aactcaatgt ctctttgtaa
    25921 attggcaaaa tctgcactca aaatggatgg tgctatcttc attcttgttt cctcctattt
    25981 tcgtttacct tctttttttg catacattgg ttttcttttt tcgatttctt gtaagaattg
    26041 caaataattg tcgtaacgtg tctgtgcgat accacctgtt tctactctat gttttacttc
    26101 gcagccaggt tctttagcat gcatgcactc tctaaatttg caatggacag aagcttctac
    26161 aaattcagga aattgtctcg gcagttctcc tgcttcaatt gtcaaaaagt caatcgagct
    26221 aaatcctggt gtatctgcta ctaacccgcc atagatagga atcagttcca catgacgtgt
    26281 tgtatgccgt cctcttccaa gtgcatcaga aatctctcct gttgctaaat tcagttccgg
    26341 tgatatttga ttcagtagcg tcgattttcc tgctccagac tgacccataa agaccgatag
    26401 ccgttctggg aagtaacgga tcagttctgt cgtatcaccc gtatgattgg gtacaatcac
    26461 cggatagcct attttagtat aggtttgctt gatctcttcg attttttctg ggtcgtctga
    26521 caagtcggtc tttgtcaaaa aaataatcgg ttcgatcgac tcgtattcca aggtaactag
    26581 aaagcggtca agtagattat aagaaaatgc aggctctacg atacttgtga caatgattcc
    26641 aagatcaaca tttgtgactg gtgggcgaac taattgattt tttctcggca agatttccag
    26701 aagatagccg tctgtttgat tttcactctc aaagatcacc tgatctccga caagcggcgt
    26761 gattttccga ttccggaaat ttcctcttcc tcttgtttga taggtctctc cgtttgcgta
    26821 tacatagtaa aaaccgctga ttgcttttct gatttgtcct ttgataagtg ccacctccgt
    26881 ttttgtttat tttaccatac gaagaggaaa gtaggtgtta ttccatgcaa acttctcaaa
    26941 gtatatggct tgaaaattga tcaaaagaga tagaaacaca aaaaagagaa tgcaacaaat
    27001 caatgtcgca ttcccttctg atatatttta ttcagcactt attttgaact ttctgaggtg
    27061 ctagctgatg aacttgtgga gctggaagat tcttcttttg aagagttgct tgtgctactg
    27121 gagctacttg agctgctaga actgtctgaa gagtcttttt cagaactaga agacgctgga
    27181 tctggtcctt tagagtaaat tacgttcaca accattcctt tggtaattgt cgttcctgcc
    27241 cctggtactg tacgaatcac tttatcttta tccaccgtgt ttgaatattc ggaagtctca
    27301 tgcccgatat attctgcacc gacactagct aaataacttt gtgcttcgct ttttgtatag
    27361 ccggagatat cattcaattt aggctctgtt ccttggctta cgacaaaatt gatgtaagtt
    27421 tcttctgcta caacttcacc cgaggctgga tcctgactga tgatcgaacc tgatggtaca
    27481 gtgtcgctat agtcataagt agcactaata ttattgatat tgaatccttg tgtaacaagc
    27541 caattacgaa cagtttcgta gttttctcct acatgactac tcaaagtcac tgtttctggt
    27601 cctttgctga ctgtgaaagt aatcgtgtct gttttaggat cgacttctgt atcttctgat
    27661 ggagattgcg aaatgatcat tccgctttct acctctgaac tgaattcctc ttctttttga
    27721 atcaagtcag cagaaaaccc taattctttc aaacttgctt cggcatcttc ataactttta
    27781 ccactgtaat catctaattt gatttttttc gtgccgctac taatatacag agtgacttcg
    27841 cgtttttgct tgactgtcgt tcccgctgcc gggtctgtct tcactacatt accttcttcg
    27901 attttgtcat ctgcaatttc ttctgttttt gttgctactt ctaatttcgc ttttgcgagt
    27961 gtttctctag cagaagcttc agaaagatca gaaacatcag gaacaacaac ttctcctcgc
    28021 ccgccagaag caaagaatac agctgttccg attcctaaaa cagcaagaat agctaatagg
    28081 atcagccacc attttttctg tcctttcttt ttaggatcag gcagaacttc ttcctcctct
    28141 ggtaaggttt cgttttctgg cttgtctttt ggcagaggca tagatttgaa tgaatcaggc
    28201 attggtgcat cttccgtaag gggtgtgata acttttgttt cattatccat cacatgaggc
    28261 tgccattttt cttcgtttgc acgagctggt gataatactg tagaaagatc atcagacatt
    28321 ttctcggctg acttataacg gtctgcaggt tctttagccg ttgcccgtaa aatcacgttt
    28381 tccagtgctt gtggcacatt tggatcaagt gcttttatag atggaagatc atcttgaaaa
    28441 tgttttaaag caattgttac agcagattca ccatcaaacg gtacgctacc cgtcaacatc
    28501 tcataaagga tgatccctaa agcataaata tctgactgct tcgttgccat acttcctctg
    28561 gcctgctcag gggacagata atgaacagat cctagcatcg tattcgtctg cgtgatcgat
    28621 gtttcagata aagcgatagc aatcccgaaa tccgtgattt ttacaacacc ttcattatcg
    28681 atcagtacgt tttggggttt caaatctcgg tggatgattt gatggttatg agctaaagaa
    28741 atagcagaaa ggatctgctg cataatattt actgctgttt cataaggaac aggataatgt
    28801 gtttggatat atcgtttcaa gtccattcct ttgacgtatt ccatcaccag atactgcatg
    28861 ttgtcttctt caccaacatc gtaaacacta acaatgtttg gatgaacgag ttctgttgct
    28921 gctaaagctt ctctctgaaa tcgtcgaatc gcagtctggt cattttgaaa gtcaaatcgt
    28981 aagactttaa ctgctacatc acgatccaag attaaatcgt gcgccaaaaa tacatttgcc
    29041 ataccaccgc taccgatatt tccagtgatt tgataacggc catttaattt tttgcccaac
    29101 tcgatcatac actgtcctcc ttatattcga taagaagaac ggtgatatta tccgctccgc
    29161 ctgcttcatt ggcacgatca atcagctcag ttactttatg agacaatggg ccttcttgat
    29221 tgatgatcgt tcctatttct tcttcagaca gcatgttcgt caagccatct gaacataaca
    29281 gcagtcgatc ttttagttgc caaagatgag tagaaacatc tacttcgact gttccaggca
    29341 tgccgacaga acgtgttaaa atatttttcc ttggatggtt cactgccatt tcttcgctga
    29401 tttctcctga tttgactagt tcattgacta aagaatgatc ctccgtcaat tgcatgattt
    29461 tatcttcacg aatcaaataa gctctgctat ccccaacatt ggcaatcgtg aaccagtcat
    29521 ctgacagagc ggccgctacg attgttgttc ccataccgtt atattccggc tgttcttgtc
    29581 cacgctgata aatcagcata ttttcttctt gaatcgattg aatgaaccat tgggcgattt
    29641 tttcatcgtc aacagcttct tgtttttccc aagcttcgcc tagattcgtt accgccatct
    29701 gactggcaat gtctccggca cgatgaccac ccatcccgtc tgctaataca gcaagcttga
    29761 gacctgaacg gctggtaaat acactggcat agtcttgatt tgtgttacgt cgtcttccta
    29821 catctgattg atattcaatc tgcatttttt cacctcatta ctttttgcgc aaacaacaaa
    29881 tgaaaaatcc atctgtgtaa aactgatgcg gatacaaagt caacattttc tcttcgattg
    29941 atgattgtag cataggattg gtcaaaacat caatcctctc aaaatcaggg tgtctttcca
    30001 agaaagcaga aacaacgtct tggttttctt cttttaagat cgtacaagtg ctataagtca
    30061 gaataccgga agactttaaa gttggtgcgc agctttctaa aatttccaat tggatttttg
    30121 gtaaattcgc taattcatcc ggctgttttt tataacgaat atctggtttt cgccgaagca
    30181 gcccaagacc tgaacaaggc gcgtctacta aaatccgatc aaactgctct gcttcgaact
    30241 gtttactgac ttctctagca tccatctttt gagcgtagac agcagaagag acacctagac
    30301 gtgctgcatt atcttcaatg agtttgactt tgtgttcgtg tacatctaaa gcgaccactt
    30361 ctccaccgca tgacggatct aaaaaagaag caatatgcgt cgtcttacct ccgggtgctg
    30421 cacaggcatc taagacatga tgttcaggct cgatttgcat agacggcgct acaagcatcg
    30481 aactttcatc ttggatcgtc atgacgccat cgtggaacaa tgagctagaa gctaaatgcc
    30541 cttttttcgc tactataccg tatggactga cttggctttt ttcagctgtg atctcttctt
    30601 cttgcaaaac agtgatggcc tgatctctgg aaagtcggcg tgtatctact cgggcactag
    30661 catggctagg ctgatatagc gataaaccga gcttttcagt ttcttcgtat ccgatttgat
    30721 ccaccagtcg tttagtcatc catagaggca ggctgatttt gacagaaagt ctttcgatag
    30781 gatcagcaat gccttgcaga tctggtgctc cttgacgctg ataattcctc aagacaccat
    30841 ttacaaattt ccctgtccca ggatttcctt ttacttttgc gatttcgacc gcctcgttta
    30901 aaatagcatg tgcagggact ttatctaaaa attctaattg gtatacagaa agataaagaa
    30961 gcgtcttgac ccagtcatcc actttttttg ctttagcgat caatggtgca acgtaaaatt
    31021 ccaatagtcg ctgatggcta atcgtaccat agatcaattc tgtaaataaa cccacatctt
    31081 tttgatttag ctcgctttgt ttgatcatct cattcaacaa aagattcgag taggcgccac
    31141 ccttgttcac tcgctctaat gtcagtaatg ccatatatcg tactgatttt ttcatttttt
    31201 tagggatttt tttcattatt tcacctgctg accaatctga acttgctgac cgcttccgtt
    31261 aaggaaatca tgtacggcct gttttccttt accagctggc tgtaattcat tgatggctaa
    31321 gacggtctgt ttaccgcaag caatccatag attttttttg tctttccgga tgatcgtacc
    31381 aggtgctttg tctgtagttt ctgccaatac ttcaaccgat aataatttcc agcgtatgcc
    31441 ctcataggtc gtgaatgcaa ttggccaagg acgcattccg cgtacttggt tgtcaatttc
    31501 ttctgcagtt ttatgccaat cgattgcttc ttgttcccgt gtgatgtttg gcgaaaaagt
    31561 tgcttctgac tcgtcttgag gtactggttt ttgtccatcc aaaatattgg gcaatgtttc
    31621 tagcaatagc tttcttccta aaaggctaag cttttcaaac atcgtcccta catcatcttg
    31681 tttagtgatt ggtatgcttt cttgcgcata gattccgcct gcatccattt ttttgatcat
    31741 ttccatgatc gttacaccag tttctttctc cccattcatg atggcataat gaacaggcgc
    31801 acctccccga tatttaggaa gtaaagaagc atggacattg attgccccta attttggtac
    31861 ttgcaataac ttttcaggca agaattggcc aaatgccgca gtgacgatca catcaggcac
    31921 caattcaatg atttcttcca tttctggcga accggagatt ttctctggct gcagcacacg
    31981 gataccgtgc ttcagagccg cttcttttac cggtgtcggc gtaattactc gtttccgccc
    32041 aactggacgg tcgggctgtg ttaccactgc ctggatctcg taacctgatt ctatcagccc
    32101 ttcaagaatc ggcacagaaa aagcaggtgt gcccataaat actagcttag tcatcaagat
    32161 gttcctccat atattcttca agttcttctt ccgggatctg ctgtatcatt ttctcaatga
    32221 acaagatacc gtctaagtga tcgatttcat gctggaaggc acgggctaaa tagccaaaag
    32281 ccgtcacttc tatctcttct ccgtctcgat cataataacg cacggtcact tcatctgctc
    32341 gcttgaccgt tccatagaca tgcggaatac tgagacaacc ttctacgtca aggctttcac
    32401 cttttgcttc gatgatttct gggttaatca gttcaaattt ctcgccttca tctacttcga
    32461 tcacagcaat tctcttgttt tgtcctactt gaggagcagc gatccctatt ccgtcattcg
    32521 caatcattgt ctcatataaa ttgtctaata aagcgattgt ctcgtccgtg attacatcga
    32581 ttggctgagc agttcttttt aatttatcat tagggtggat caatatagga tagcgcataa
    32641 tttggccctt tcttaaataa agtttaatgg ttcgttgtca attgccacaa aaagaccttg
    32701 tcgctgttct ttctggcttc cattcaaaat ttcatccaaa acatgaggaa gattcggttc
    32761 atgtttatat ttgatgatta gttgataata atatcggttt ttcactctca aaatcatgct
    32821 gggcgttggc cctaatagca agctttgagg gcttaacact tcttttagct gattggcaat
    32881 ctgaaagatt ttctttgccg ctacttgttc ttcaggatgg ctggcggtta ttttcacagt
    32941 aaagtaataa ggaggatagc ctccacgatg ccgtacatgc atttcctgct gataaaactg
    33001 ctcataattt tgttttttag ccaattctat ggcgtaatgt tgaggattga atgtttggat
    33061 cacgacttcg cctgcttttt ccgctcgccc tgctcgtcct gaaacttggg taagcaattg
    33121 gaatgtatgc tcactagaac gaaaatccgg taaattcagg gaggtatcag cattcaacac
    33181 cccaactaat gtcacttctg gaaagtccaa acctttagca atcatttgtg tccctaataa
    33241 tatatctgct tcttttgcac cgaatttttg taaaatctgt tcgtgtgccc cttttcttcg
    33301 agtggtatct acatccatac gcaaaatcct agcttgcgga taaagttctc ggagttcctc
    33361 ttctactttt tgagtacctg ttccatagta gcggatttta ttgccgccac aattaggaca
    33421 gcgattggga ataggttctt catgtccgca ataatggcag cgcattgaac gtgtatccat
    33481 atgcagtgta agagagatat cgcaattagg acatggaaga acaaatccac agtccctaca
    33541 catcacaaaa gacgaatatc ctcgacgatt gagcagtagg acagtttgtt cttttttgtc
    33601 taatcgattt tgtatttttt cctgcaaatt agcagaaaaa gtagaggtcc gatgattctg
    33661 aaactcttca cgcatatcta cgatctcaat agctggaagc tgtgcagctg ctttggctcg
    33721 gtggtttaac tgcaataact gataaacgcc tttttgagct cgtgctcttg attctaaaga
    33781 gggcgtcgcg cttcctagaa ctattgggca atgatgatat ttactgcgcc aaattgctag
    33841 atctctcgca tgataacgcg gtgtctcatc ttgtttgtaa cttgattcat gttcttcatc
    33901 gataatgatc agcccgatat ttttcagcgg ggcaaaaata gcagatcgtg cgcctactac
    33961 tacttgcgct tcttcccgct caatcttgcg ccattcatca tatttttcac cttgggaaag
    34021 tccgctatgt aagaccgcaa ctgattctcc gaagcgtcct ttgaatcgct cgaccatttg
    34081 cggagtcaat gcgatttcag gcactaacat aatagccgtt ttattttctg acaaaacatc
    34141 agcgattgcc tgaagatata cttctgtttt cccgctgcca gtgattccct ccagcaaaaa
    34201 gacctgatct ttttgctgct gacctgctgt gatgatttgt tcgacagcat ttttttgttc
    34261 tgcattcagt tccaatgccg tcgtttggtc aaatactcgg tctttataag ggtcgcgata
    34321 acgttctgat tctataaact ccagccagcc cttttctttt ccttgattca agacagcagt
    34381 actgattcct ttatttttga aataagcaat tggttcttct tggctcagtt cagataaaca
    34441 caaaagaagt tctttttgtt tcttggcatt ttgccgtaat tttgcccatt cttcttcgat
    34501 ttgcttttca gttaacaaag aacggaccaa acgaatcgtt tttactttat ttcgtgtatg
    34561 gacttcatat ttgatatcta ctaattgctc ttggcgccag cgaatcaatt gagaaaggct
    34621 gccttcttct tctgcttcct tccaggaaat cacttctcgc tgatcaaaca atacctgaac
    34681 ttctggtgtg tctgccaaag gatagatcaa tttatcatat tctgctttca tcacactcgg
    34741 aagcatcgtt tgtagacaag tgattttgaa tgcgtaagta atttttttca tataatcagc
    34801 taatgaaagt aattcttcat tgaccaccgg agcaaggtct agcaaacgaa taactgcctt
    34861 caaagatgga ttagctgatt cttctgattt ttggatagcc ataacaaatc cttggacatg
    34921 acgattgcca ttaccaaaag ggacttctac tcgcatcccg acttgcaaag ctgtttccat
    34981 ttcagaggga accaaataag tgaatggctg atcggtctgc atagtaggta cgtccacaat
    35041 gacttcagct gttaatgtca tggttcgttt cctccttttt ttgtcttttc ttatcaagcg
    35101 acaaaaagtt ccttgcctat tttactagag atcgatggat ttgtcttatc ttctgccaaa
    35161 tcctaacaaa aaattaacag cagataagaa aaaaaagaac tgtgtcaaaa agttcagaca
    35221 cagccttttc taccagacaa taagtggcga atgtttgaaa aggaaacagc tgggtttgct
    35281 tttcttttta gatgttcgct ctatttttct ttattacatt ttttgctctt cacggatacg
    35341 tgattccaat tcgtgttgtt cacgctcttt ttgtgcttga cgttcctctt cttccatctt
    35401 caaacgttca cgttttaatt caggatgtgg atcattgact acatttcctg catcgatttc
    35461 ttctaaagct tgaccgacgc tttttactga atcaaaagaa tctagagtag gctgtgcact
    35521 tgcatccaat tcatgcgcgc gtttacttgc taaaatcact agagaatatt ttgaatttac
    35581 acgatctaat agtgagtcaa ttgaaggttt taacatcata agactacatc tcctttaaca
    35641 ttttaatata tttaccgatt acgcgatcta ctcgaaaatg ttcactggca ataatgtttt
    35701 tgattcgttc aactgctagc ggcacttcat catttacaac agcatagtcg taaagagcca
    35761 tcatttcgat ttcttctttt gcaactttca ttcgttcttc gattacttca tctgcatctg
    35821 ttcctcggcc tacgatccgt gattttaatt ccgctaaatc tggcggagtc aaaaagatga
    35881 atacaccatc gggcactttt tctttgactt gttttgctcc ttggacttca atctccaaga
    35941 aaacatcttt tccttcatcc aatgtcttgt tgacatatga caaaggagtt ccataataat
    36001 tcccgacata ttctgcgtat tccagcatct ctccagcttc gatcattgat tcaaactctt
    36061 ctttgcttcg gaagaaataa tcaacgcctt cgacctcccc ttcacgcatt ttacgggtag
    36121 tcattgagat cgaatactga aaatcattat cctcactctc aaaaattgct tttcgtactg
    36181 tgccttttcc tacaccggat ggaccagaca acacgattaa taatccacgc tctgacatga
    36241 cgacgtcctt tcaactagtc tttttgtact tatcgtttat tttgcacttt ttttctgcaa
    36301 ctttcaaggt tatctttaat tatagctaga aattggtaaa aaagctaccc tgtaccaaga
    36361 ggtcgtaaaa aagctgtcct gcatcaagta ataagaacag ccaaacataa acagcttctc
    36421 atgtttttcg tttggttggg gttattatcg cagatgcaag cttttgaacg ccgtgtataa
    36481 gaggtcgtga agaagccgat tagtttcgag tatgaagaaa aattttgtga aaatagtttc
    36541 tcacattttt gcataaattt ggcttaatac cgagaaaatg gtttttgaac atcacttatt
    36601 caaaataaaa aaagattgtg acacgaattt tgtcacaacc tttaaatgta ttcctagagc
    36661 aaagaagcta agcgaagaaa tccaattctg attatttatt gtatttcttt gttcagcatc
    36721 cttgctaaaa gcccatattg gacaaagtat tcactacacc catgatctca tcttttcgag
    36781 aacgtgcttt ttctgtcgga tcttctacct cttctgtgtc aattcgaaca ataaatttcc
    36841 gattcatcgt cacgtaagca ccgtcgttga tcaaaataaa cagttcgttc tcattatagt
    36901 ctgcacaggc atctttccat acgtcaaagc cgtttttttc agaagggata tcccgtttaa
    36961 ccacagtttt tccacttaat tcgtggaacg ttacgtcata atatttcatt atctctacct
    37021 ctttcgtcat tcaatatttt gtacttgttc tctgattttt tctaagatcg tcttagactg
    37081 gacgacttga tttttaattt cgattgcatt tgatttggaa ccgatcgtgt tgatttcccg
    37141 attcatttct tggatcagga aatctaattc ccgacctaca ggacattgtg cttcgataag
    37201 ttcatctagt ttttgtacat ggatcgccag acgatccagt tcctcgtgaa tatctccgcg
    37261 ttccaacaag atggctagct ccgtcaacaa ccgttgctca tcgactttcg ctccaagaaa
    37321 ttcctccagc tttttttgat accttatttg aaattccttt tcatagattt ctacaaaact
    37381 atcgagtttt tttagtactt ctttgaattc ttcagtattc tttttcaaca ctaaagctaa
    37441 agcttgacct tctttttctc gactcgcctc aatagaatca agtgcgcttt tcaatgtatc
    37501 tagagctaac tgtgccaatt cttccatgct ctcttccggt ttttcttcta ccgttacgaa
    37561 gttttcgtcc agcgcgaagc gttccgccat ccgactaatt gacacttgat tttgactacc
    37621 gtatcgttgt tgaattccgt ctgtcaattg agtgataagt gaatcaatca attcccagtt
    37681 gatgacgatc tgtttttcgt ttttgccaat ataagctaga ttcacaaata cttcgattcg
    37741 accgcggctt aactgctgtt taataagctg acgaaaatcg ttttcaacaa agttcaggat
    37801 tttaggactt cgtatttgaa catctagaaa acgctggttg acacttttta tttcaatatc
    37861 taactgatac gcttttgttt cgcggatggc tttgccaaaa ccagtcatac ttttcattcg
    37921 acagggtcct tcctcattac atattttcta ttgctttttg cagttgttca aactcttcgt
    37981 tcgtcaatgt caggcctttc cccatttttt catggtctgg cgcccaatct cgaagatcga
    38041 attttggcgg gcgaccattc cagctgacta ggttcagttc tttacgccac cccttgttgt
    38101 tttctgacaa tatagcgatt tcttctacga tttcatatga aaattcttgt gccatggttg
    38161 ttcctccttg agataatata aatataggat cagtaatgtg tcaactggtt gcttaagcaa
    38221 ttcatgctgc aaacgatcct tgcgttttcc ttgtagcaga taatcaaaat aaacagtttt
    38281 cgtgcgctca ttttgtattt tttgctggta ttttcgatac cttcgccatt cttcagtact
    38341 taattgacca atttgtgcca ataaatcatc cggcatactt tttatatctt gttggcagat
    38401 catttgaatc atcatgtcta cttgatagat ttcattgggc agtaaaaaat gtttttttgc
    38461 taaaagttct agcatcgcca atccgcatgt ctctggtacg accctgttct tatataaatt
    38521 acgcagtttt tgccaaaatt ttatgctttt gaaaaaagat aattctaact gaatttcttt
    38581 tgttaagtaa gacaaaaatc ctcgccagta tgttcttgca ggtttaacag aatgaaatgt
    38641 ataccagttc ccatagtaat agcctaatcg ttttttcatt tccagatagc ctaattgtaa
    38701 atttaattgg ttcctttggc tatcaaaaag cagaaagctg cctagtgtcc acaatgtttg
    38761 acatttccaa tggataaaaa tgtctggcat acgaattttt ttcgctgggc ctggcccttg
    38821 cacatctacg acaaatgcct ctgttgctcc tttgttaatc gcaatatcaa taggtatttt
    38881 gttgcgatac ccaccgtctg catatttatt ttttccgatc tttcgataag ccatagcggg
    38941 ataaaatgaa gcagaggcga gtatccaatc tggtatttct tctgtttttg tctgttggat
    39001 atcagtcact acttccgcta gttctggcag tttagtagac accgtatata aacgtatttt
    39061 gggattatgt ttgagtaagg acaaatccaa attgtctttg accatctttt ccaatggagc
    39121 agaagaaacc ccgccttcaa ttagtgctgt tttcgtcatt tggcgtcttt ctcgatagaa
    39181 gcgttcacga aggtcttcaa ctgcagccat ttctggtaac gcaagcactt gtcttgtcga
    39241 cagctttttc cataaattca cagctttttt catatctcct tgtaaaatca atgcgccgtt
    39301 caacgcacct accgaggtac ctgtgataat ctcaaagttg atatcatgtt ccttcagcgc
    39361 ctgccacaca ccaatctgat aagcaccgtg tgctcctcct ccacctaaaa caagtgctgt
    39421 atgatagacc agctttttat ttaattgtgt ggttccttga tagccgtttt tatgaaaaat
    39481 acgcaaccat tcttctgata gaggagattg aaataaaaaa caacagtttt ctttaataaa
    39541 aaaacgagcg caagcttcca tataccgaaa aaattttttc cattcaaaag tttcaccttc
    39601 aatcaacaga ttattaaaaa taacatctcc tctactttta gcaatagtaa aatagacggt
    39661 atattttttc gatactgctt taaaagcaca ttgctttttt gcagaacgcc aaaaagcgtc
    39721 tctactttct tgatgacttt gaaaaaatgg aaggggttgt tttgcttgct ggataggcga
    39781 atacagcgac attttctgtg aaaagtaaac tttttttatc tccatcgcgc tctccttttt
    39841 cttcaagtat accagtacgt cataaaaagg tcatgagtct cgtattcgac tttgtagatt
    39901 ccataagaaa acaattcata aaacatcctt taaataaaaa atacaaaaat cacaaaaatt
    39961 aattgaaaat gagagtgttt tcaatgaaaa cgtgattttg taatggaatt ttaaaataaa
    40021 agaaacaagc ttttttaatg caaatgttgt aaaataaaag agattaagag gaaataagag
    40081 gaggaacatg atgactgagt cagtttatgt acatattgat accacaagta atgctgtttt
    40141 aacaaaaggg ctgactgcta ctgactttgc aaacagtatc gtgcattttc ctcaaaactt
    40201 gctcttgctt gatccatctg cttctgctgg agaatatgaa tcccatacag ggctgaaagt
    40261 aatccgtggt acagaaaata ttcagcgttt cttttcctct tctcgtaaca ggcgtggatt
    40321 cgatgaattg aagtggatcg actttactga tttaacgatg ctgaaagaat tgacaccttt
    40381 agaaatttca gaattattat attttggtca tatgaaaaca catcttcatt cgccgttttt
    40441 ttataaacta cagaataatt ttgtatactt cgatcttaat gatcagctga atcggattta
    40501 ttatcgctat ttagatgaat tttataggat ttttgctagt aaattaagtt cgatcttgtc
    40561 agataagatc aatgtaaaaa aatctttttt caaaaaagaa acacctgttg aaaaaatcag
    40621 tgtggaatta ttgaaagaaa tgcgtaattt gatgcaggaa gggatcattt tttcttttga
    40681 tcaagttggt ttgatcgatg gtaaatatcg tatcccaatc tatgtgattg aagattatat
    40741 ttggaaatta aaaggcaccc ggtatcgaga agaggaaatc atcgctactt taatctactc
    40801 tgtcaccgat cgacactggc aattggtaga agatgccgat ctttcttatc tgccattgaa
    40861 gtagatctat ttcttatcaa aaaataaaaa ggaaacaaga aactaggaca tgattctgtc
    40921 tcaagtttct tgcttctttt ttatttacag ctcctgtcgt ttatctggca caaaaatcga
    40981 aggagtcgtt tgttggatcc ctaataaaac gatgatcgtt acaatagctg tactcaaccc
    41041 gctggcacca ttcattacga aagaaaagag ccaagaattc atcccccata gtgcatacgc
    41101 tccccagaaa accactcctg caataaaatg ccaaaaatat ctggaaagtg cgccaatcaa
    41161 tgcaccaaac acgatgcttt ttctaatttg tttcgtatta tcgtctacat agcctttttg
    41221 gacatttgaa gccatgagcc ctgctgcgcc tgcaaaagta taggcaatcg ggtactcaat
    41281 caacacttga acgacactta aataataaac ttgtcccaac ggaaaatgta ggatgcccca
    41341 aatgaaacct gccagcatcc ctgcctttgt ccctcttctt aacgcaaaaa gagtcaatgg
    41401 aatctgccct aatgaaatag aaaaactgct gccgatctgg atcggaatca acgacaacac
    41461 catcgctaac gctgcaacaa tcgttccttc tacccaaact ctattttttc ccataaaaaa
    41521 acttcctcct ttgaataaaa aagtcacaaa ggaggaagca gctttcgaaa atagtcaaac
    41581 agctgtttat tcacaattcc tacgctcgca taaccgatac aggtacgaag ggtttagaaa
    41641 tagattcaat ctcagcccaa ttggactccc ctttgtgagt ttatttatta tttatttttt
    41701 gtttcaaaca atggactaac tggtttgttt tcatggatac gtttgattgc atctcccatt
    41761 agtccgccaa cacttacttc atcgattttg tcgattttac gatcttctgg aagatagatc
    41821 gagtctgtaa caactagacg ctcgatagct gaatcttcta ttctttgtaa agcagggccg
    41881 gataatactg gatgtgtaca tgaagcatac acactagttg caccagcttc tttcaaagca
    41941 ttggcagcca atgtgatcgt acctgctgta tcgatcatat catcgatcag tacacaagtt
    42001 ttgcctttga cttgtccaat gatattcatt acttctgcaa catttgcttt tggacggcgt
    42061 ttgtctatga tcgcaatcgg agatttcaaa aattccgcta atttacgtgc ccgtgtgaca
    42121 ccaccatggt ctggtgaaac aacgacaaca tcatcgcctt tgattccttt ttctaagaaa
    42181 taattggcaa taagtggcgc acccatcaaa tgatcgactg gaatatcaaa gaaaccttgg
    42241 atttggactg catgaaggtc caaagtcagc attcttgttg caccagcttt ttgaatcatg
    42301 tttgctacta atttcgctgt gattggttcc cgtgcacgtg ctttacggtc ttgacgcgca
    42361 tagccataat aaggcatgac tacgttgatt gtttttgcac ttgctcgttt cagtgcgtca
    42421 atcatgatca gcaactccat caagttatca ttgactgggc tgctcgttga ttgaataaca
    42481 tagacatgcg atccacgaat actttcttca atgtttactt gaatttctcc atcactaaat
    42541 tgagtaacag atgattttcc taactcgacg ccgactgctg ctgcaatttt ctctgctaat
    42601 gggcgattgg aatttaacgc aaaaattttt aatcttgggt caaagtaatg ttttgacatg
    42661 gggacctcca ctttcttttt cacaactcta gaattctacc taataaatag tagtcatatt
    42721 ttttaaataa atcaagtgat tttgcaaaag tcttagttta gataagggag tttttttgca
    42781 tatccttctt tattgacttg tcttgctctc gcaattgcca gcgcatattc tggaatattg
    42841 tctgtaattg ttgacccggc agcaatcgaa ctgtttttag ctacctcgac aggtccgatg
    42901 atattcgtgc tagaaccaat aaagctgtgg tcgccgacag tcgtatgatg tttattcttt
    42961 ccatcatagt tgacgaagac aacaccacat ccgacattga tttcttctcc cagcgtagca
    43021 tcaccaacat aagtcaagtg accgacttta gttcctttgc cgatttgagc atttttcact
    43081 tccacaaagt ttccgatatg gacgttttcg ccaatttcag cttttggtcg taaatgtgca
    43141 taaggtccca catctgcatg tttcttgaca tggctgcttt caatgactga gttttcaatg
    43201 acgacgtgat cctcaatcct actgtctacg atttttgaat gtgacccgat gacacaatca
    43261 gaaccaatga ctgtatttcc ttggatttgt acacctgctt cgatcaatgt gtctggaccg
    43321 atttctacgc ctgcatcgat gtatgtcgtt gctgaatcga caaagcttac gccattgacc
    43381 atatgcatct ggttaattcg ctttctcatg atctcatttg ctttagctaa cgcgatccga
    43441 tcattgactc ccattgattc ttcaaaatca tccgtttgat aagcagcaac tgtatggcct
    43501 tcttctttta agatttcgat gatatctgtt agatagtatt caccttgagc attgtttgtt
    43561 ccaactttgc ttaacgcatc gaacaaagct tcgttgtcaa aacagtaagt tcctgtattg
    43621 atttcttgta caagagcttc ttctggtgtt gcatcttttt gttccacgat tttttctacg
    43681 atcccaatat ggtcacggat gattcgtcca tatcctgttg ggttttctgc ttgtgccgtc
    43741 aagatcgttg cacttgcatt ttttccttgg tgatattcaa aaagattgtt cagcgtttca
    43801 gtagtcaata atggtgtatc gccactgata actaacgttg ttcctttttt tccttccaag
    43861 aaagaagcag cttgcaaaac agcatgtcct gttcccaatt gttctgcttg taacgcatat
    43921 ttactgcgtt ctcctagttg tgctttaact tgttctgctc cgtgtccaac gatcgtaatc
    43981 acttcatctg gtttcgtttc actgacccga ttaatgatat gttctaccat aggtttacca
    44041 gaaacgggat gtaaaacttt atataatttt gacttcatgc gggtaccttt ccctgccgcc
    44101 aaaataattg cataacgtgc gtccaactgc gtcactccta aatatagttt gctgatttca
    44161 gtttatccca gtatacccat tttttcaaca aaacaagtga ttttctttta tcccagcgtt
    44221 ttctggataa aaaaatagat agaccataac gggcctatct atttggtaac cggtgctctc
    44281 ctgccaactc ctcggtcaca agtcacacta ctcataaaac atgaaaagct gttttttgaa
    44341 atcgtttctt gtgacttaga gttaaacggt aggcttacaa cctcttcatt aaacgttttt
    44401 caatcagctg accttcggta ttagctcaat aaacggcaaa atatgaggag caatttttcc
    44461 gtttattgag ctaatactca ggacaggacg ctgatttcac aacctctaga taaacggtgt
    44521 tcaaaagcca gtttctcggt attaagccaa atttatgaaa aaatgtggaa agccattttc
    44581 acaaaatttt tcttactact cgaaactaag cggctttttc acaacctctt attctgaaaa
    44641 ataatttcct ggcacaaccg taatattttt cgtttgagta tctacatctt tgacataaag
    44701 cagtgacgta taatcatcga tggcgcgatg accgttgaat tttgattcgg caaatacagt
    44761 gatgccaaca agttctgatt cgaattcttc aatcaagctc ttcattccgt tgactgttcc
    44821 gccgcctttc atgaaatcat ccactacaag gacacgtgaa ccacgtttca aacttctctt
    44881 agacagttcc atcttttcaa ttctttcaga agatccagac acatagttga cacttactgt
    44941 tgatccttct gttatttttg agtcccggcg tacaataacg aatggcgcat tcagataata
    45001 ggacacagct tgggcaatag gtacgccttt tgtggctaca gtcattacag catcgatttt
    45061 ttcaccaagg tatttagaag caatgattct tccaacttga cgcagcagtt caggttctcc
    45121 taacaaatca gagagataaa catatcctcc tggaagcaga cggtcttgtt ctgatagacg
    45181 ttctgctaga gattcaatat attttttcgc ctcttcatat gaaatttcag ggatgaacaa
    45241 tacaccacct gcagcacccg ggattgtttc caaggttcca taccctcgtt ctttaaatgt
    45301 tttcttgatg attcccaaat cttcactgat agaagattta gcagattcat aacgttcggc
    45361 aaagcttgtt aaggaaatca attcatgcgg gtgattcaat aaatactgtg tcatgtcaac
    45421 tagacgttca ctgcgacgta ctttcaccta ttccaactcc ttttaagaaa ttttatcgtt
    45481 ttacattata taagtttttc ttcaaaaatt cgagcatttt atgaaaaaat aagaaaatag
    45541 ttcggtattt attaaaataa aaagaagcct ataaaaaatt tttcgttttt ataaggcttc
    45601 ttttctttat aatttagtta ttttttcttc tgaaggcaac caatattcgt ttgatgatat
    45661 ttacaatcag gaacaaagca ataaagacta atgtgattgt tgctcctgga ggtgtatcta
    45721 gataaaacga gctagttagt cctgacagca tccctagaaa tcctacacaa acactgatag
    45781 caatcacgac attgaagctt ttgcctaatc gcataccgat tgctgcggga agaaccatga
    45841 ttgcggatat caaaagtgca ccggcaatcg ggatcatcac agcaatagcc acaccagtaa
    45901 tcacattgaa catcatcgac atcaaatgaa cgggtagccc atccacgtgg gcggtatctt
    45961 catcaaaagt cagaacatac atcggccgtt tgaataaaaa gaacaatata ccgatggcaa
    46021 cgaataagat tcctaaaaag atgacttgct cccatgtaat ggtcacgatc gaaccaaaca
    46081 gataggattg gatacttgtt gctgaattcc ctccgctcaa attcatcaat actaacgcta
    46141 gcgccaaacc accagccatt aaaatggcaa tggagatttc tgaataggtt cggtagatcg
    46201 ttcgcagata ctccaatatc acagctgcta atacaacgac tagcatggtc gtaagtgtag
    46261 gattaaggtt caaaaagaat cctaacgcta cccctgctaa agagacatga gaaagcgtat
    46321 cagccatcag cgattgtctt ctgatcacta aaaacacacc tagcatcggg gcgattccgg
    46381 caatgaagat agcggcaaga aacgctcttc tcatgaattc atatgaaagc aacgccattg
    46441 agaatcctcc tttctcacca gtcggatctg tctgtccgca tactgtttga tatcttcatg
    46501 atcatgggtg atcattagaa ctgatttccc atggacatgc gcactatgtc ggagaagacg
    46561 ataaaattca tttctggatt cttcatccat acctgttgtt ggttcatcaa gaacaaataa
    46621 gtcagggtca gtagcaaaaa tacgcgctaa actgattcgc tgcttttgtc cgccagacaa
    46681 ttcacctatt cgccgatttc gcatatccca catccctaca gcttctaaag cacgctgtac
    46741 atgttgatga tctttttcag agagacgctt gaaccagcgg cctcttggat atcttcctga
    46801 acggactaat tcgatcaccg tactaggaaa acctgcattg aaagatgcaa cttgttgagg
    46861 aatataaccg atacttaatt tttttccttc ttgatttttc tcagcaatct ttatcattcc
    46921 ttttgaaggt ttcagtaatc ctaacgatgc tttcaccaag gttgacttgg ctgctccatt
    46981 ttctccagtt aaaatgacaa attcacccgc atctacatga taagagacat cttctagtac
    47041 aggttcatca tcatagtaaa aggtcaaatc agatatttcg atataacgca ccttacaacc
    47101 tccattctaa aacttaattg atactttctt ttaaagcttt cagatttttt tccatgacag
    47161 aaatataatt ttcgcctgct ttgatttgtt cattagtcaa gctttctaaa ggattcaaca
    47221 cttctagctt cactcctgtt tcattcgaca atgtctcagc taccttcgaa gaggcatttt
    47281 cttcaaaata aatcactttg atgttgtttt tcttcacaaa ttcttttagc tcagctaagc
    47341 gacttggtgt gggttcctga tctggtgaaa cgcccgaaat cgctacttgt tttaagtcgt
    47401 attgattcgc taaataagca aaagcagcat gctgagtgac aaatgtgcgg tttgttgcat
    47461 cttttagctc atcggagtat ttttgatcca gtgcttcaag ctttttgata taagcatcgg
    47521 cattcttcgt aaaagtttcc tttttatctg gatatttttc gcctaattct tcagcaatcg
    47581 ttctgacttc ttttatagct aataccggat cgagccaaac atgtggatcg tattcatgtg
    47641 aatgaccatg cccttcttct gattcttcat gttcgtctgc ttcttgcgat tctaaacggt
    47701 cgattccttt agctgcttcg atcatcaagg tctgtttgct atccactgaa tcctttaacg
    47761 aatccacaaa aaattccatg tctgaactat tatacacgaa aacatctgca tcggaaattt
    47821 ctgctctttc ttttgcactt ggttcgaaat catgcggctc cgttccagca gggatcaaaa
    47881 gtttcacgtt tccttcatcc cctacgatct cttttgtaaa atcatacatc ggataaaaag
    47941 tcgtaacgat cgtcaaatcc tcttttttgt ctgcttcctt gttcgtattt ccacatgctg
    48001 caaacagtaa agcacctatc attaccgtag ctgtcaaaag atattttttc atttatatgc
    48061 tcctttcaat gaacaaatcg gaattttacg atttattaac gtgaactaat gtatcaaaat
    48121 aaaaaaacac agtcaataga aatccatcaa tttctgattt aagcatgtat attcttgatt
    48181 aaatcgtaaa atggatgagt tgctgctcat atctagccat ttcactacaa taaaaaactg
    48241 aagaatacca ttttaggatt cctcagtttt tcatcaccta ttttacttct tatattttat
    48301 tgcagggttc gtactaaata aacttcctca caaaaacctt ttaacccatt atatactctc
    48361 tgcgctcttg aataatgttg acacaaggca aaaacggttg gtccgcttcc actcatcaat
    48421 gcagcatctg ctccgtactt gatcatacgc tctttgattt gatggatgac tggatgccgc
    48481 tttcccgtta tatcttctaa actgtttccc atttttttga tcatctgctg ataatcttgc
    48541 tctcggatgg cttcagcaag tccgtggatg tcttgatgtt ggatggcttg cgtatctact
    48601 tctctaaaca ctgtacgtgt agagacactc attcttggtt tgaccaacac aacccagcac
    48661 tgtggcatag aaggtaatac ttggatttct tcccctttgc caccgacaaa tgccgtactt
    48721 ccgtagacac agtaaggaac atctgtaccg acttccaaac cgatttctgc cagttcttct
    48781 aacgaacagc ccagattcca taattggttg atccctctta gagcagctgc acagtctgta
    48841 cttcctccgc ctaatccagc tgctactgga atattcttct taacaaagat cttgacaccg
    48901 gttttgatat tgtatttatt ttttagcaat aaagcagctt gataaacatt gttccgttca
    48961 tctaccggta aaaatgcttt atttgtttct acaatgattt tgtcttctgt tatttcttca
    49021 aaaaatagat gatctgccaa gtctacgctc gacatcacca tttccaactc atgataccca
    49081 tcttgccgtc tatataatac atccagtcct aaatttatct tggctggcgc tttttcaatc
    49141 aattccatcc tctcacccat tcgaaaagtc taagtcgcaa gtattctatc atagggaaaa
    49201 ataaaagtat agcttatgtc tgcctagtgg ttgattttgt catcgtttca acagctttca
    49261 cagaattttc tcttcataat ccaaacaagt tctagtgatt cttataattc tgtgagcact
    49321 tcttctgcca aactcggaac atttcctttt tcttttccta tcagactgag tagctgcatg
    49381 gtagcaaatc cgaaattact tcctttccta taagcaaaat aacgtccttc ccaatgatcg
    49441 acatatttta atttcttttc ataagcagac tggaaggaat agaaaaaatt accataatta
    49501 tatacgatat gcatgacttt ttcttgaaag aaagaaaaat ctgtttctcc aacattagct
    49561 aatggagcta agcctagatt ggcttccgag tagcccattt tctcgtatac aataaacaga
    49621 ttggctaaca gatagtcagc taattcctca gattctttag gtaagacccg caacaaatca
    49681 tatcccgcct gcttcttcgt catcggctga gcggtgatga agccaacgac tttttgatct
    49741 ttacggacaa taccgacacc gctagataat acatatgatt tatcaaatcg tcccacagag
    49801 aagtattttt ctcgtgcacc ttgaagccat ttttgtgaaa cttcatttac agcttgatgt
    49861 aattcttccg gcagttgatc gtaccaagta aaatggtatc cttctttcat caaacgttga
    49921 tattcaagtt gctgactcag ccgagacaag tcttctgttg ctagatcaac aatccctgct
    49981 tcacctactt tcgtgaagtg aaaacccaat tcatgaagca tcactacgta gctttctgat
    50041 atcttataaa acgcaagctg atagcctaaa caatctgctt gtttcataaa ctgattcgtt
    50101 gctgcccgca tcattttagg attgccaact ggatctccta aaacaaagca tttgtttcct
    50161 ttgatctgat aaccaaaaac gacttgatct tggtcgtctt cttggtaata aaaataactg
    50221 taacctgaca agcgaagctg atggcttgta gctgtgcctc cgtatgtttc caataaacgg
    50281 tcaaaacggt ctttttcgta ctcactgcca agcttcgtag tatcttcagc taaatattga
    50341 taaagcgcca ctaaagctag caatgagatg cccaaaccaa taagccctga gaaccacaca
    50401 tcatctgaag gaaacaaaat aaaatgattt cctgttattc gaccgactaa aaagcgtccg
    50461 ctgtgatagc ctgcaattgc gtaaacgata aacaaaaagc cgaacaagct agcatcaaag
    50521 attatagctc cccaagaata aacgaatttt gttcgataaa attcttttct ggataaccac
    50581 acagctaaca gaatcaagac atataccaat atcaactgcc aagataacgt acgtgtgatt
    50641 gtatttaaaa taccaaaaga tagtaaagca atcgtaggca gaaatgcctt tttgactttt
    50701 actgaaagtg ctctagcaag gccgagtaat aaaaagccaa ccaatagatt cactgtctga
    50761 tctaaaaaat tgaatgagaa cggcaataat acttgaaata gccgactgat tgcagacaga
    50821 ttagtgattg ttgatagaag taccatcatg atccccgcaa aatagacagc acttacgagc
    50881 acgatatgcg caaccttttg gaaaaacagt cgcggaatgt tatctaaaaa tcgattgatt
    50941 ttgactcctg tatgtgtgat gaacaataga agtcccgtca taaaaggtag aacataataa
    51001 aacaaccgat aatataatag ccaaactact gctacatctt gccgaacaga caattgactc
    51061 attcctaaga tcatcaaaac gtcaaaagtc cccattccac ctgggaccat cgtcagcatt
    51121 cctatcaatg tagcaatcat gaacatagga tagatcgaaa gcatcgaaat atctattctc
    51181 atcaacttgc cgatgatcaa aaataccgca agggctcccg tccattgtcc aaaggatgcc
    51241 agtagcagac caagcaagcc ttttggataa aactcgaaga acaatgtctt tctctttaga
    51301 taagcaaaaa agaaaatgac tggtgctaaa aaactaccgc cgaaaagcca gatccaatag
    51361 cttcgaaaaa tactttctga ctgaataaaa aagacatcaa taaatgtaag aaacgaccat
    51421 acagacaaac cagtcagcat aaatagtgcg acttttgata cagtggctaa aaccattttt
    51481 ctatttgtct gctttccata aaaactagcc cgcagacttg ctcctaccac accaccaaaa
    51541 ccggcgagat tgttgatcgt gtttgttacc cacgcagcaa gaagaaactc ttttctttcc
    51601 atttttggtt ttccttgttt ttctaagact ctgatcgtca cccaatcata caacaacatc
    51661 ggagtgacac ccagcagtcc agccagaatc atgagcagga tcgtcatgcg gctttgttgt
    51721 cccatccttt gccaaatatc ttgccaactc atgccattag caatatttgc gacttgattt
    51781 gccacaaaga ctaacacgga gccgaaaaaa atcagtttta aaatcagact atgttccttt
    51841 atccattgca gcatcaagta tcgtttattt ttcacatttt cccattccta acttgtatac
    51901 ttttgtgtca taccccaatg ttatcttatt tattttaatt tttccacttt agacctgttc
    51961 tttgcttgcg atgatagaaa aagaaagata tcctaatgct aaaggagagg ataacatgaa
    52021 agtaggattt atcggcacag ggaatatggc acaagctatt attgatggtt tattaaaaaa
    52081 aggaacagtc tcgaaagaag aggtgttcgt ttccagtgga cattttgaaa atgcacaaaa
    52141 atttgctgct gaaactggcg tccatgcatg caaaagtaat caggaagttg catcacaatc
    52201 agatatcgtt cttttagccg tgaaaccaaa aatcattgaa aaagtattgg aagaactaag
    52261 agaatatagc cagaaagtct tattcatttc tattgcttca ggaaaatcat taacagattt
    52321 agaaacagcg cttgaagatc ctcaggcctc catcgtacgt gtgatgccga atgtcaatgt
    52381 cagcgtagga gcaggcgttt ctgcgatttg caaaaatgaa gctgccacgg aggaacagct
    52441 tcagcaagct acgatgattt ttgaagcaat cggcagcgtc tatcctttag cagaatcaga
    52501 tttcagtaca ttcattggcc ttgctggcag ctcacccgca ttcgtttaca tgctgatcga
    52561 tgcgatggga cggactggtg tactgaatgg tttgtccaaa cagacagcca ctgagattgc
    52621 tgcaaaagca attatgggtt cttgtcaaaa attcctttca agtgataaaa atccatggga
    52681 acttgtagac caagtttctt ctcctggcgg tacaactgtt gcaggtgtag ttgccttaga
    52741 agaagcagga ttcatcccag caatcatcaa aggaatcaat acgacgatcg agaaagatct
    52801 tgagatgttg aataaaaaat aatgatagca atgttttttc gtaccttaca aaaaaagaag
    52861 agctgtggct tttgccgcgg ctctt
//
LOCUS       DARPZJ010000015        48760 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.015, whole genome shotgun sequence.
ACCESSION   DARPZJ010000015 DARPZJ010000000
VERSION     DARPZJ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.015"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(49..213)
                     /locus_tag="SLE23_001095"
     CDS             complement(49..213)
                     /locus_tag="SLE23_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468012.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            508..1836
                     /locus_tag="SLE23_001096"
     CDS             508..1836
                     /locus_tag="SLE23_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HEI8468013.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2038..2871
                     /locus_tag="SLE23_001097"
     CDS             2038..2871
                     /locus_tag="SLE23_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HEI8468014.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2887..3624
                     /locus_tag="SLE23_001098"
     CDS             2887..3624
                     /locus_tag="SLE23_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEI8468015.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3779..4747)
                     /locus_tag="SLE23_001099"
     CDS             complement(3779..4747)
                     /locus_tag="SLE23_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEI8468016.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            4979..5812
                     /locus_tag="SLE23_001100"
     CDS             4979..5812
                     /locus_tag="SLE23_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HEI8468017.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5846..6685
                     /locus_tag="SLE23_001101"
     CDS             5846..6685
                     /locus_tag="SLE23_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8468018.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6711..7271
                     /locus_tag="SLE23_001102"
     CDS             6711..7271
                     /locus_tag="SLE23_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8468019.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7470..9191
                     /locus_tag="SLE23_001103"
     CDS             7470..9191
                     /locus_tag="SLE23_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEI8468020.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9356..10498
                     /locus_tag="SLE23_001104"
     CDS             9356..10498
                     /locus_tag="SLE23_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEI8468021.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10514..11725
                     /gene="thiI"
                     /locus_tag="SLE23_001105"
     CDS             10514..11725
                     /gene="thiI"
                     /locus_tag="SLE23_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEI8468022.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12298..12945
                     /locus_tag="SLE23_001106"
     CDS             12298..12945
                     /locus_tag="SLE23_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEI8468023.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13074..13290
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13338..15983
                     /locus_tag="SLE23_001107"
     CDS             13338..15983
                     /locus_tag="SLE23_001107"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEI8468024.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16293..17606
                     /locus_tag="SLE23_001108"
     CDS             16293..17606
                     /locus_tag="SLE23_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEI8468025.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17596..18249
                     /locus_tag="SLE23_001109"
     CDS             17596..18249
                     /locus_tag="SLE23_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8468026.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18304..18975
                     /gene="radC"
                     /locus_tag="SLE23_001110"
     CDS             18304..18975
                     /gene="radC"
                     /locus_tag="SLE23_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEI8468027.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(18870..20222)
                     /locus_tag="SLE23_001111"
     CDS             complement(18870..20222)
                     /locus_tag="SLE23_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8468028.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLAEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(20288..21577)
                     /locus_tag="SLE23_001112"
     CDS             complement(20288..21577)
                     /locus_tag="SLE23_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEI8468029.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(21664..22368)
                     /locus_tag="SLE23_001113"
     CDS             complement(21664..22368)
                     /locus_tag="SLE23_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEI8468030.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            22568..22834
                     /locus_tag="SLE23_001114"
     CDS             22568..22834
                     /locus_tag="SLE23_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8468031.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            22847..23005
                     /locus_tag="SLE23_001115"
     CDS             22847..23005
                     /locus_tag="SLE23_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468032.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(23002..23232)
                     /locus_tag="SLE23_001116"
     CDS             complement(23002..23232)
                     /locus_tag="SLE23_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEI8468033.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            23304..23459
                     /locus_tag="SLE23_001117"
     CDS             23304..23459
                     /locus_tag="SLE23_001117"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468034.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            23616..23771
                     /locus_tag="SLE23_001118"
     CDS             23616..23771
                     /locus_tag="SLE23_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468035.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(23768..23992)
                     /locus_tag="SLE23_001119"
     CDS             complement(23768..23992)
                     /locus_tag="SLE23_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEI8468036.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            24259..24594
                     /locus_tag="SLE23_001120"
     CDS             24259..24594
                     /locus_tag="SLE23_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468037.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            24827..25768
                     /locus_tag="SLE23_001121"
     CDS             24827..25768
                     /locus_tag="SLE23_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HEI8468038.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            25770..26660
                     /locus_tag="SLE23_001122"
     CDS             25770..26660
                     /locus_tag="SLE23_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEI8468039.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            26703..27503
                     /locus_tag="SLE23_001123"
     CDS             26703..27503
                     /locus_tag="SLE23_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEI8468040.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            27518..28369
                     /locus_tag="SLE23_001124"
     CDS             27518..28369
                     /locus_tag="SLE23_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8468041.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            28366..28725
                     /locus_tag="SLE23_001125"
     CDS             28366..28725
                     /locus_tag="SLE23_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HEI8468042.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            28740..28901
                     /locus_tag="SLE23_001126"
     CDS             28740..28901
                     /locus_tag="SLE23_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEI8468043.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            28898..29224
                     /locus_tag="SLE23_001127"
     CDS             28898..29224
                     /locus_tag="SLE23_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468044.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            29221..30036
                     /locus_tag="SLE23_001128"
     CDS             29221..30036
                     /locus_tag="SLE23_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HEI8468045.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            30175..30486
                     /locus_tag="SLE23_001129"
     CDS             30175..30486
                     /locus_tag="SLE23_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEI8468046.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDV
                     K"
     gene            30483..30713
                     /locus_tag="SLE23_001130"
     CDS             30483..30713
                     /locus_tag="SLE23_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468047.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNIELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            30720..30923
                     /locus_tag="SLE23_001131"
     CDS             30720..30923
                     /locus_tag="SLE23_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HEI8468048.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASDAIRKFGISILNDDRKWEEMR"
     gene            30920..31219
                     /locus_tag="SLE23_001132"
     CDS             30920..31219
                     /locus_tag="SLE23_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468049.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVINNEV"
     gene            31209..31373
                     /locus_tag="SLE23_001133"
     CDS             31209..31373
                     /locus_tag="SLE23_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468050.1"
                     /translation="MKFKIFEEDTRYKLEKELNDFAKNNEIQHISLATSKRGYANYYA
                     AVVSYVSREV"
     gene            31462..31875
                     /locus_tag="SLE23_001134"
     CDS             31462..31875
                     /locus_tag="SLE23_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEI8468051.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILVALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            31888..32274
                     /locus_tag="SLE23_001135"
     CDS             31888..32274
                     /locus_tag="SLE23_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468052.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            32825..33049
                     /locus_tag="SLE23_001136"
     CDS             32825..33049
                     /locus_tag="SLE23_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468053.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            33067..33495
                     /locus_tag="SLE23_001137"
     CDS             33067..33495
                     /locus_tag="SLE23_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468054.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            33473..34891
                     /gene="terL"
                     /locus_tag="SLE23_001138"
     CDS             33473..34891
                     /gene="terL"
                     /locus_tag="SLE23_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HEI8468055.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            34903..36438
                     /locus_tag="SLE23_001139"
     CDS             34903..36438
                     /locus_tag="SLE23_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEI8468056.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            36518..37396
                     /locus_tag="SLE23_001140"
     CDS             36518..37396
                     /locus_tag="SLE23_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEI8468057.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            37398..37715
                     /locus_tag="SLE23_001141"
     CDS             37398..37715
                     /locus_tag="SLE23_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468058.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            37842..38465
                     /locus_tag="SLE23_001142"
     CDS             37842..38465
                     /locus_tag="SLE23_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEI8468059.1"
                     /translation="MIMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            38480..39370
                     /locus_tag="SLE23_001143"
     CDS             38480..39370
                     /locus_tag="SLE23_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HEI8468060.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            39393..39608
                     /locus_tag="SLE23_001144"
     CDS             39393..39608
                     /locus_tag="SLE23_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468061.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            39620..39961
                     /locus_tag="SLE23_001145"
     CDS             39620..39961
                     /locus_tag="SLE23_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468062.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            39961..40332
                     /locus_tag="SLE23_001146"
     CDS             39961..40332
                     /locus_tag="SLE23_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468063.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            40325..40720
                     /locus_tag="SLE23_001147"
     CDS             40325..40720
                     /locus_tag="SLE23_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEI8468064.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            40722..41099
                     /locus_tag="SLE23_001148"
     CDS             40722..41099
                     /locus_tag="SLE23_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468065.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            41100..41708
                     /locus_tag="SLE23_001149"
     CDS             41100..41708
                     /locus_tag="SLE23_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8468066.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            41708..42049
                     /locus_tag="SLE23_001150"
     CDS             41708..42049
                     /locus_tag="SLE23_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468067.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            42291..45080
                     /locus_tag="SLE23_001151"
     CDS             42291..45080
                     /locus_tag="SLE23_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEI8468068.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNGGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVASSMESFLKVIAANIPRAVSFLSNLFDAVQKFGSALKFMMPFLVPA
                     TTAFGALMFQLKGIPTIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIVGAVVGAI
                     AVFGYFMATNEEVRNKVISVWNDVKDSVLGVLKNIKDWGIDTWNSAKEMASNAVESVK
                     DAWSGIKEWFSNTWQGIKNGATGLFDKTVETSMNAVDSVKNAWSNTKQWFSDIWQSIK
                     DSATEKWNEIKGSIMEVAGPLITGLKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LTPVLFITSMISGGWEETKNNMIGVWNNIKESALNIWESIKNIFVSYITNIYFAALNI
                     WTGFKLTLINIWNEVVSQAKSIWINVKYFFINLWIDIKYFAIQKWIELKFGIIQTWID
                     LKYNAITTWNNIKQFFKDTWQNIKDIAYNTWISIKNSMINTWNNIKESFWNIVTGIVN
                     SAENAWTNLKNGVSKAINRVKEIFDSLREINLFEIGKNIIDGLINGVVEKWNALKKTI
                     KGIAGSIKDSIKGALGIHSPSRWMRDMVGKNIVQGIIVGIDKEKSKLDQTMTDLVKTP
                     SVQPVITGSNSQPVVQAKQNTSSNAVNEIHLHLNVYGDLPDSMIKQIAKKMKTELTRQ
                     MKRDADAVGGTLYAT"
     gene            45070..45810
                     /locus_tag="SLE23_001152"
     CDS             45070..45810
                     /locus_tag="SLE23_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEI8468069.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKAYYKNVTRKIECYYKAPSIDLVQEWEDRITEWLDMNSYSDFILYYDQQYIYQ
                     AIVTEAPEFKGTRKTGNIVPFEFTVSLRPFKENYSGRFAIQQIKAFELFNPEKYASKP
                     LIKLSGSGDASFYINNDKYDLKLLDRELYIDSKLEESYRKLDDNLEHQDHVTLFLDFP
                     FLYPGKNEIKWTNNIHSFEIIPRWWRKV"
     gene            45807..48518
                     /locus_tag="SLE23_001153"
     CDS             45807..48518
                     /locus_tag="SLE23_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEI8468070.1"
                     /translation="MIPRIYSPTETDFSTNGLGILKDTTKCEIYEVANGKYELELEYP
                     LGTRFDEYFENDYQIKAKSNDQEEYHIFFIDDKDIDTFLDTVTIYAQSRTNRLGRRAV
                     TFAGVDSKTGREAMAIIENNMDKKSDIRLYSDITTVSSTTFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRDNIGTIRYGKDLSGLKVKLDWTGVKTRIIPYADPQS
                     DAGTTSRIYGSPVDSEYINNYPDVYTEHVQFTEEQGVKDVNSLNKIAKNYFKTINPGC
                     DKPKISITVEFDKLTDTEEGKEFAKIRNYGLFDTFKIYHRKYKLYFESKVSGVQYDSL
                     SEKVLKLEAGDAQVAFYQQQAVTIQDKLKDYATNNYMSSFNDYVSSMIAGQGNAGGYV
                     VLWPKEKPSNIFIMDSPDLNKAKEVLRMNKNGIAFSKNGWNGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSNSSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVNGKEITGNNSGGSDPGTIPPQLTTEAEKRAWKIWTMLKARGYSEYAAAG
                     ILGNIQGEVGASMNPDTEQLGGPAYGIVQWDGSAYPLVGSPTWNGREYVQRLMNTAGI
                     QEDYRSIEAQVKLLDWCMFNGQWLGKVNPTTVSGFKSINDAKSAAYAFEMNFERPASA
                     HPERQNYAQSWYNKLHGLTSPEPGGNFICPIQKPVTVTSECGWRTSPINGGQEFHNGI
                     DLVNGNPNTPVFAALDGEVVQAGANYYDWYGNYVVIKHNNGKWTGYAHLSRIDVSVGQ
                     KVQKGAQIGLMGTTGPSTGEHLHFQIMKNYWPQPVVDFENPRNYIQF"
     gene            48531..>48760
                     /locus_tag="SLE23_001154"
     CDS             48531..>48760
                     /locus_tag="SLE23_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HEI8468071.1"
                     /translation="MSKWNVVLSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKI"
BASE COUNT        16814 a         7709 c        10107 g        14130 t
ORIGIN      
        1 tcacgtatgt tgtaatcttt acgaaagagt agagttggct actcataatc aaccatactt
       61 cccatcatcg ctaaatacga aataaatcag cattcctaca ccaatcaaag cacaagctgc
      121 accaagaaaa gggatgacat tcccaaagtt atctgtattc ataagtatgc caccacccac
      181 aaacaaaaag ccgccagcaa tcaggttttt cattttattc atctcctttc ttacgttata
      241 gtatttcctt ctttcaatga gtattttgaa agctatctta ttgtatgatg ttcttctagg
      301 cctcttcttt attatacagg ccattttcgt tatctcatag aaatattcct ttttatctga
      361 aaactattgt ataccgtatg acatttttct tcatgaagtt gtaagtatat tctcattcaa
      421 atgaaaattt catcatagaa gagattgtat ttctaaattc ttaagagtaa aatacgaagt
      481 ataacttgga tttggaagga tgattggatg aaagctatta cgcctgatat gacaacaaaa
      541 tttaacaaac agtttcaagc aaatatcaaa cagcaggcat tgcagcgggc agttgtgaag
      601 aacggaatta ctgcttctgc tgaaaatgtt tcagcacatg tggagaatac accggtattt
      661 tctatagatt tggctacggg gaaagtggct aatcaaatgc aatcggggcg ttgctggatg
      721 tttgctgcac tgaacacatt ccgtcataag atgctgaatc aattccattt aaaagagttt
      781 gaattatcac aaaattacac ttttttctgg gataaatatg aaaaggcaaa ttatttctat
      841 gaaaacatca ttgcaacagg aaaagaggca atcgatagcc ggaaagtagc tttcttactc
      901 gctactcctc aacaagatgg cggccaatgg gatatgatcg tttcattatt ccaaaaatat
      961 ggcgttgtgc ctaaatcggt gatgccggaa agtgcgaata gttcaaattc tcgagatttg
     1021 aataactact tgaacaaatt actgcgtaaa gatgcagtag tgttacggaa aatggttgct
     1081 caaggagaaa cattagacgc tattgaagaa aagaaagaag aaatgctaga aagcatttat
     1141 aacttcttag ctatctcatt aggaacacct ccaaaagaat tcgattttga gtaccgcgat
     1201 gaagaaaaga actatcatct tgaccgagga ctgacaccac aaatttttta tgataaatac
     1261 atcggtgtaa aattagatga ttatgttagc gtgatcaatg caccaacaaa agacaaacca
     1321 ttcaatcgtt cttatacagt agagatgcta ggaaatgtcg ttggcgggaa agaagtcaaa
     1381 tatctgaatg ttgatatgga aactttcaaa aaattagcga ttgctcagct tgaagaagga
     1441 gaatctgttt ggtttggttg tgatgtaggt caatcttcta ctagaactag tggcatcatg
     1501 gccttagatg cttattcaat ggatgatcta tttgatacgg attttacaat gactaaagct
     1561 gaacgtttag attttggaga aagtctgatg acccatgcga tggtattgac cggtgttgac
     1621 ttagtagacg ggcaatcaac aaaatggaaa gtcgaaaata gctggggcga aaaagttgga
     1681 aagaatggct tctttgttat gagtgatgcc tggatggacg aatatacgta ccaaatcgtt
     1741 gtaagaaaag atttattgac gaaagagcaa ttaaatgcgt tcaatgaaga accaattgtt
     1801 ctatctccgt gggatccaat gggtgcttta gcatagacga gtatttcaat gaagagtatg
     1861 tagtaaagat aaaaagagct ggcttaagcc agctcttttt atctttaaag tccattccct
     1921 gttttttatg gtccctgtgc tataattcta aataaaggat aaggattgga aataatcctt
     1981 ttatcattaa aaatatgatg acgaagtaga ataaaattgg gagtaggggg gaaagtcatg
     2041 gatatccaaa ctgttttatc tgatctgaaa ttaaatggta aagtgattcc agttgttggt
     2101 ggcgatgtta atcagaccta tcgtataaaa accgaacatc gtgcttattt tttaaaaatc
     2161 catccgaatg taaaaaaagg attttttgaa gcagaagtag acggattaaa agaactgtca
     2221 gcattcgtac gtgtaccgga tacgtatatg ctaggtgaaa caagtgaagg cgcttatttg
     2281 ttaatggaat ggatcgagcc gggaaaaggg gatcaacgag atcttgctgc agctttagct
     2341 aatctccatc agcaaacagc gccacaattt ggttttcgta aagataacta tttgggtaca
     2401 cttgttcaga aaaattcttt tgaagaagat tggtggactt ttttctttaa agatcggctt
     2461 gaatcccaga tttctttggc agaagaaacg aatcgatgga atgtacagcg tcaagaaaag
     2521 tatctgcgat ttaaagaacg tgtattgaaa tcggttgaac caaaaaagat cactccacgc
     2581 ctcttgcacg gagacctgtg gagtggtaat gtgttctttg accagcaagg gcatccagtt
     2641 tttgtcgacc cagctgtttc ttatgggaat cgggaacaag atattgcaat gagccagtta
     2701 ttcggtggtt tccgaccgga atttttagat gcttatcaaa ctatatttcc attagaaaag
     2761 ggatggaaag accgactgcc gatttaccag ttatattatc ttttggcaca tttgaatatg
     2821 tttggagaaa gttacggttc ccaagtagat caattactag aaaattttta agaggagggc
     2881 gtgtttttgg caaaaaaata taccaaaaag catgaagttt catattatga gtgtgacatc
     2941 aaccaaacga tgacatttcc ttcgatgtta ggagtagtta tcaaaacgtc tgaagatcaa
     3001 agcgaccagt tgggaagagg cagtgaattc gtcaatagct ttggacttac ttgggtcatc
     3061 acgaattatt ccatggagat taatcgtctc cctagagtcg gtgaagtaat ctcagtaacg
     3121 actcaagcca tggagtacaa taagtttttc tgttatcgga acttctggat ccatgatgaa
     3181 gatgggaaag aattagtcaa aatagaatct gttttcgtat tgatggattt tgtgaatcga
     3241 aaaatgagca gtgttaatga agagatcatt gctccttttg agagtgagaa gatcaagaaa
     3301 atcaagcgtc aggaaaaaat tgaaaagatt gattcgggct tcatgttgcc atatcgtgtt
     3361 cgtttttatg atatcgatag taatcagcat gttaataatg cgatgtattt taattggatc
     3421 attgacgtat taggatatga ctttttgact acgcatgttc cagaaaaagt aattattcga
     3481 tttgataaag aagtagagta cgggaatgag atcgaaagcc attttgaaca aatccctatc
     3541 gaaaatggtg tcaaaacaaa acatgaaatc cgaatgcaag aacagctgta ttgtgaagca
     3601 aatattatat ggaaaaataa ataaaaaaga ggttgtgaca gaagggggca acttcaagaa
     3661 ataagaagaa atttacgaaa attgtttctc aaatttttgt aaattttcga cttagttttc
     3721 gaagaagcta tttttgtcac agcctctctt tttaagttta gctattagat aatgatgttt
     3781 agttttggat aaacgaaatc aattcttcac ccgacaaacc atagtttaca gcaatcaata
     3841 gttttaaacg tgctttttga ctattaatac tgttacagaa aataatcccc attttttcta
     3901 gttcttttcc cccgccttca taatcataaa caggctctgc gattccattg aaacaacgag
     3961 aaacaagtac tacagggatt ttttggacaa gaagcttttc caaagcagct aaggcttgtg
     4021 gagggagatt ccccgcacct aaagcttcga ttaccaaacc gtctactttc gtatgggcga
     4081 tggcttccaa taagtcccct tgcatcccag catatgcttt aacgatcggg atagtcccat
     4141 ctacagcgga aatgtccagt cgctttgttt ctaaaagttc ctgcaagaat aaaattcgat
     4201 tcttagttac taagccgatg ggacccaatg taggtgttcg gaaagtagca acatttgtgg
     4261 tatgggtctt tgtcacgtag cgtgcagaat ggatctcatc gttcatgacc accaaaaccc
     4321 ccttatctag cgcttcttca caacttgcga cacgaatcgc actttcaaaa ttataaaggc
     4381 cgtcacttcc aagttcatta cttgaacgca ttgccccagt caaaacaatt ggtaatttgt
     4441 tgccaatcgt tgtatcaaga aaaaaagcag tttcttctaa tgtatctgta ccgtgtgtga
     4501 tcaccactcc ggatatacct gatgcataag cggacaagat acgttctttt aataccaaca
     4561 tgtgagaagg catgatgtgt ggtgagggaa gattgaagat atcttcaact aataattcta
     4621 catgcttggg gattgtgatt tctgcatcta ataatgggtt tgccacatca ggactaacac
     4681 cgcccgtgag catgttttct ttcatggcga tcgttccgcc ggtgtgtagt acaagtattt
     4741 ttttcatttt acagacttcc ttacgaataa ttttgcatag ccgttaaatc ttattgtata
     4801 ctatataaaa gagttttgct atcagtgaag aataacgaat agcctaactt atcataaaaa
     4861 agctgacctt attaaaatgg aaaagactca accttgacct cctaatacaa tggagtatct
     4921 ggttgagttt cttttacaag aaagcagcca aggaaatcaa tcacgaaggt ggccggaaat
     4981 gatcagaatc ggattaacat cgtttaaaga acatgacaaa ttaactggta aaaagaataa
     5041 cactctttat gaatatgcag ggtttctacc cttagtggaa ttagatactg cctattatgg
     5101 aattccccga aagtcctcag ttgagaattg gataagtgaa gtacctgaat catttcgctt
     5161 tgtagtcaaa gtctatcaag gaatcagcgg tcaaggagac tggaagcctt attatcagac
     5221 cgaagaagag atgattgcgc attttttaga tgttatgtcg ccaatggtag atgctggaaa
     5281 gatgttttgc tttttagtcc aattcccctc atcattcaaa tgtacgaaag aaaatgtcca
     5341 gtacttgcgc aaacttagaa agtggtttga gggttatcct gtttctatag aattgcggga
     5401 ttattcttgg tacagcgatg aatttcttga acgtacaaga aactttatgt ctagagccgc
     5461 tttttcttta gccatcatcg atgagccaca gttgctgaat acaacgattc cttttgatcc
     5521 atttgtcacc aatccgaact ttgctctttt tcgattccat ggtaggaatg cgcaaggatg
     5581 gcaagcaaat gataaagagt ggcgtaaaaa aagaacgtta tatcgttatt cagaaaaaga
     5641 actgcaagaa ctagcacatg aagtcaaagt agttgattct aagacaaaag aggtaggtgt
     5701 gatttttaat aataattctg gtggtgatgc ggctgaaaat gcattagcac tgcaaaaaat
     5761 attaaatatc aagccagatg gactcaatcc aacccaaatg gatctgtttt aagggcttat
     5821 tttattcaag aaaggggcga agtctatgat caaagctatt ttttttgata ttgacggaac
     5881 attggtcacc aatcgttcaa aagcgttgga atcaacaaaa caagcaattg aatatgctcg
     5941 gaaaaacggc attttatgcg gtgtagcaac ggggcgcagc ccagtaaaga tcaaagaaat
     6001 cattgatgaa ttggaattag atatgtatgt cgtgtataat ggtcaactgg tttttactgc
     6061 agatcgcacg attatcgacc acccttttga acaaaaagta ttggaacata ttgttgaatt
     6121 tgcagatgag aaccatcgac aaatcgtttt tggtgcgaga aatcggttag atggatcaac
     6181 gacgatgcta ttaggacaat cgatttttat caagcgacta gtcagctttt taccgcgtaa
     6241 attcccggta cgtctgatga aaaaaatcct ccaggttttt agccctcacc gacaaaagga
     6301 tcgttatgaa acgttagaga tattaaaaga accaatttat caatgtatat tgctcagtcc
     6361 ggagtcagaa cagaaaaagt tagaacatcg ctttcccgag tgtacgtttc agcgttcaaa
     6421 tacgtatact gtagatatca tcccaaaagg tggttcaaaa ttactaggca tccaagcttt
     6481 cgcaaatgct gtcgaaattg aaatggaaga aattatggca ttcggcgatc attacaatga
     6541 tatcgagatg ctgaaaggtg taggaattgg agtggccatg gggaatgctc agatcgaagt
     6601 aaaacatgct gcagactttg tgactcaatc aaatgaagaa gatgggatat acgaaggact
     6661 gaaacacttc ggtctgattt attagtcaat gaaagaagga aaaaatcagt atggaagcag
     6721 agacaccttt tcaaaaagta gaaacattcc acaaaacttt tgatccaaga agaccagaga
     6781 tacccacggc ttttacagaa aatgaagctc atacacgtgc tgcgttcaaa atagaagaac
     6841 ttgttgaatt tgttgcagct acttcaccta ataaagaaca actgcatgaa gctgttatgc
     6901 tgctgcacga agcattagat aaagcagaag aaaaaatact tggtaaaaca cagtggggaa
     6961 gtgatccgct ggttgaacaa gtagatgcac tgacagatat cctttacttt acttatggtt
     7021 ctttttcatt actaggaata gtgcctgatc gaatattcga aatcgtccat caggcaaata
     7081 tggggaaatt atttccagat ggaaaacctc attatgaccc tgtaacaaat aaagtgttga
     7141 aacctgaaaa ctggcagatg gaatatgctc cagaacctaa aatcgcggca gaaatccaac
     7201 gtcagattca agaagcgatt gctaagaaga aatccgctga tataggcatg tgcacaaatg
     7261 aaaaagagtg atcagagttt cactattttt gttatcttta tacgatggaa aaacaaaaga
     7321 ttttcgttta agttagtgaa tgcatgaaaa tagtatgcta taatctagaa tagatgtctt
     7381 ttgcacgaga gacgtattat ttggatttat gccaagcaga acgccatctg ttgcataaaa
     7441 gatgcatact gaaaacggag gaaccataaa tgggaaataa tgttatcatc ggaatcgtca
     7501 ttgcaatcat tatagtcgcc attgtcgtct ttttggttag ttacttgatg aagaaaaaaa
     7561 accaagatcg attggatgcc ttagaaaaac gcaaggaaga attatttgac ttgccagtga
     7621 ttgaagaagt cgatgatgtt aaaaaaatgc atctggttgg gcaaagccaa aatacctttc
     7681 gtgaatggag tcaaaaatgg aatgacatat ctacttcctc gttcgctgaa ctagaaagtc
     7741 aaattttcga agtggaaaac ctcaatgaaa gttttcggtt cttaaaagga aaaaaagcag
     7801 ttgttgaagc agaagctaca atggaccaaa tggagaaaca agtgacggaa atccgtgaag
     7861 gtctaaagga attgcgggaa acggaagaac gcaactcact agctgttcag caggcacttg
     7921 acgtctatga agaactgaaa gaaaaagtca gagaagacga gcatgaatac ggaccagctc
     7981 tttttgaatt gcaaaaacag atcaaagtga tcgaaaaaga atttacgcag tttgtgactt
     8041 taaacacttc tggagaccct gttgaagccc gcgaggtttt ggataaagca gaaaaacata
     8101 cgtatgaagt ggaagctctg atgaaaaaaa ttccaccgct gtatgaggag ctccatacca
     8161 ctttccctga acaacttgaa gaaatcagtg atacttacga gaaattgatg gaagaacaat
     8221 atgtattccc agaagaagat cttgctgaag atatcgcaaa agtaagtcga agaattgaaa
     8281 attcattagc caatcttgaa aaaacagaag ttgaaacggt cgaatttgaa aaccgtgaaa
     8341 cagctgattt gattgattcg ttatatgata tcttagaacg ggaaatggaa gctcagagat
     8401 atgtaaaaac taaccaatca acgattgcag agtatatcaa acatacaaca aagaataacc
     8461 gtcaattatt gattgagctg gatcacacat ctcaaagcta tacattgaac cacaatgaaa
     8521 ttggccgtgt acgaggtttc caaaccgaag tggaagaaat ggaacgtcaa aatgaacaga
     8581 tgattccaca gatccgtcaa cacgaaattc cttattcaga agtgcgcacg ttctataaaa
     8641 cagtcttcaa agtcttagaa gatatcgaaa agcaacaagt agagatcgac gactcattac
     8701 atgaattgag aaaaggcgaa aaagaagcgc aagaaaagat cgatacattc gaattcaaat
     8761 tgcgcagttt gaaacgtttt gtagaaaaac aacgtttgcc tggcttgccg aatgattacc
     8821 tagaattctt ttttgttgct actgaccgta ttgaagaact aagtgttgtc ttgaataaaa
     8881 ttcgagtaaa catggaagag gtcaatcgtt tagttgctct atgtgaagaa gatctagaat
     8941 tattagataa gaagacacat gatttagtag atgcagcagc attaacggag caaatgctcc
     9001 aatatgcaaa tcgttatcgt catacacacg aagaagtgag agaagcaatt gataaaagct
     9061 actatttatt caataaagaa tatcactatc aagaagcatt agacgaaatc ggtacagcat
     9121 tagagcgagt agaacctggt gctttcaaac gcatcgaaga tttttatttt aatcatccag
     9181 acttagtata aagcaaaaaa gttagtaaac cagcaagagc aagacggatt attgtcttgt
     9241 tcttgtcttt ttttgtatat ttgaaaattg aaacaagtga aaatttcacc tgctcttgaa
     9301 agcaccttgg acaaccgtta taatagaaaa gaatttcaaa aaagaggggt ttcttatgat
     9361 atattttgat aacagtgcaa caaccccaat ctttccgcaa agcttagatg catatgtaaa
     9421 aaccagtcag cggattattg ggaatccatc aagcttgcat gatttaggca atcaagctaa
     9481 ccggttgttg cagcaagcaa gaaagcagat cgctgatttg atccatgtag aaccagaaga
     9541 aatctatttt acttcaggcg gaacagaagg agataactgg gtattaaaag gaacgatgat
     9601 cgaaaaaaga gaatatggga atcatatgat catttcagga gtcgaacatc cggccgtcag
     9661 cgagacagca gaacaattaa aagaattagg aatcgaagta agtatcgccc cagtggataa
     9721 acgcggattt gtacgtgtcg acgaattgaa agaattaata agaaaagaga cagtattagt
     9781 ctctgttatg gctgtgaata atgaagtagg atcgattcag cccatccagg aaatcagtga
     9841 tcttttggat gattttccta aaattcattt ccatgtagat gctgttcagg cgattggaaa
     9901 agtaccattc tcgcaatggt tgacagaaag agttgatttt gcaacatttt cagctcataa
     9961 attccatggc ccacggggaa ctggtttcat ttattggaaa aagggtcgtc gtttagcacc
    10021 attactgaca ggtggagggc aagaaagaaa tcagcgaagt gggacagaaa atgttccagg
    10081 tattgtggct atggttaaag ctttacgttt atcattagag ataaaggaac aaaaacctga
    10141 gcagacacaa cgcttaaaag tagctctaat caatgcgttg aagacgtatg agaaagtgac
    10201 gattttttca gaaggaactg actatgcacc gcatatttta tgttttgctc taaaaggaat
    10261 tcgcggcgaa gttctcgtcc atgccttaga agaaaaacaa atatttgttt ctactactag
    10321 tgcctgctcc tcacgtaaac atatggcaag cagtacattg cacgcaatgc atgtaccaaa
    10381 tgatctggct acatctgctg ttcgaatcag cttagatgaa aacaattcgc ttgcagaagt
    10441 cgagcaattt atgattattt tcaagcagct ttataagaaa ttttctgcaa tcaattaaaa
    10501 gaggagtgtt cttgtgaaat acagtgaaat tatggtccgt tatggggaac tttcgacaaa
    10561 aggaaagaat cgaaaaagct ttatcatgca actagcacaa aatgtcagac aagctttgaa
    10621 agactttcca gaaatcaaaa tccatgctga tcgggaccgg atgcatcttt tattgaatgg
    10681 cgcagacggg cagctagtta ttccaaaact agcaaaaata tttgggatcc aaaatttctc
    10741 tccaagtatt cgtgtagaaa aagatgtcga agttttgaaa caagctgttc aagacatcat
    10801 gaaagaaatt tatactggga aagaaacatt taaaattatc gctaaaagaa gcgatcacca
    10861 atttgaattg acaagtaatg aattgaatca aacattaggt aatgctgttt ttgatatttt
    10921 cccgcatatc caagttcaaa tgcgtcaacc agatattcca ttacgtgtag agattcggcg
    10981 tgatggcgct tatctatcgt atgaaacgat caagggagct ggaggattgc ccgtaggaac
    11041 aagcggaaaa ggaatgctta tgctttctgg ggggattgat tctcctgtag cagggtactt
    11101 tgccatgaag cggggagtgg aaattgaagc tgttcatttt gctagtccgc cgtatacaag
    11161 tgaacaagca ctgcaaaaag caaaagatct aacagccaaa ctagcacctt atgtgggaac
    11221 gatccatttt atcgaagtgc catttaccga gattcaagaa gaaatcaaaa agtcagtgcc
    11281 acaaggatat tggatgacaa ttactcgtcg aatgatgttg cgtttgaccg atgaaattcg
    11341 ccgtattcgt catggtttag tcattttgaa tggtgaatca ttaggtcaag tggcttcaca
    11401 aactttgcaa agtatggtgg ctatcaatga agtaacgaat acgccaatca ttcggcctgt
    11461 agcgacaatg gataaacttg aaattattga agtagcagaa cagatcgata catttaatct
    11521 ttctatccag ccttttgaag attgctgtac gatttttgct cctccacagc caaaaacacg
    11581 ccctcaactg gaaaaggtcc atcaatatga agagcgttta gcaatagatg aaatgatcca
    11641 acgagcacta gctggcttga agatggaaga gatacaagca gaatcgtcta atgaaaaaac
    11701 tgaagaattt tcagaattgc tataagaggt tatgaaaata gtgttttgac cagagtatta
    11761 gagaaacaaa acgaaaaaat agctccatgt attttaccgt ttttgaacta atgtcgaaga
    11821 ttagctgatt gaataccatt tatcaagaag ttatggaaaa gccggttctt ttttactaac
    11881 tgaaaaataa aattttattt agagatcaag ctacagttga taaatgatat aaaaaagaga
    11941 atttcccatg aaatagcgag gttgtgacag aagtgggcag cttcaagaaa taagaaggaa
    12001 tttacgaaaa ttgcttttca aatttttgtg aaatttcggc ttatttttcg aagaagttac
    12061 ttctggaaca ccgtgtatca gaggttgcga aaaagctgcc ctgcatcaag taataagaac
    12121 agccaaacaa aaatagttcc tcatatttta cgtttggttg agcttattac cgcagatgca
    12181 agcttttgaa caccgtttta tttgtctcac acccttttcc ttcctacttg taaccttgct
    12241 cccgtgttag aaacatgtta cactaaatat gtgaaattat taacaaggag cgtcgttatg
    12301 cgagaaaaaa cagatacact gccaaaagca actgcgaaaa gattaccttt atatttacgc
    12361 tacttgaaga tgctggatga ctcaggtata agtagaatca aatcaaatga gttcagcgaa
    12421 atcacccaaa ttccttctgc aacgatccgc agagacttct cgcaattagg cgagctaggc
    12481 agaagcggat atggctatga tgtccctttt cttatcgatg tattcaataa tatccttaat
    12541 actaaagaag aaaaacgaat cgcattagta ggatatggaa atcttggcaa agcattgaaa
    12601 cacaacaatt ttagaagaaa tgaaaatcta aatatcgtgt gcgtctttga taatgatcca
    12661 gcactgatca atcgagtaat tgatggagaa atgatctatc cgattgatcg tttcgcggag
    12721 atagccaaag caaaaaatgt gacagtagca atctctacgg taccaagtaa atattcacaa
    12781 tctgctattg atgaaattgt caaaggaaat gtaaccgcta tacttaattt tgcgcctgac
    12841 agagtaactg tcccagctta tgtcaatgtt caatacattg atttgacaac cgagttgcag
    12901 acgcttattt actttgatga gaattactca gaagtttttt cttaggaaaa tttgagtagg
    12961 cttattgatc ttgcgagaac tcgtcgtaat tctttcaaaa attttttagt actaaatgaa
    13021 gtggtttttt cacgaccact tgttgactaa aaaaaaaaac cattgtagaa tgaagcataa
    13081 cgctgaacaa gaggagtaac tggcacattc attcttagag agagaactat ctgctgaaag
    13141 gttctcaatg acaaccagtg aaggtagctt gggagtttct gtcttgaatg gagtagagat
    13201 agacgagtcg tgatcgttaa ctcacttgag aggcaataat gattgattat tgcaatttag
    13261 gtggtaccgc gtaaatcata cgtcctagaa tacgaaagta ttttaggacg ttttttagtt
    13321 taaaggagga aaacagcatg acggaagaaa ataacctatc aacaaaatat aatccgcaag
    13381 aagttgaagc tggacgttat cagcattggt tagaacaaga tttgtttaaa ccgagcggag
    13441 ataaaaaagc aaaaccttat tcaatcgtaa tcccgccccc aaatgttact ggaaaacttc
    13501 atttagggca tgcttgggat acgaccttgc aagatatgct gattcgtcaa aagagaatgc
    13561 aaggatatga tactttatgg ctgcctggta tggaccatgc aggaatcgcg acacaagcaa
    13621 aagtagaagc gaagcttaga gagcaaggga tttctcgtta tgatctaggt cgtgaaaagt
    13681 tcatcgatca agtgtgggaa tggaaagaag agtatgcgag ccacatccgc gaacagtggg
    13741 ctaaaatggg cttatcttta gattacagta gggaacgttt tacattagat gatggattat
    13801 ctgaagcagt acgtaaagtt tttgttacct tatacgaaaa aggtttgatt tatcgtggtg
    13861 aatatatcat caactgggat cctcaagcac gaacagctct atctgatatc gaagttattc
    13921 ataaagatat cgaaggcgcc ttttatcata tgagctatga actagcagat ggatcaggcg
    13981 tagtagaaat tgcgacaacc cgtccagaaa cgatgttggg agatacggcg attgctgttc
    14041 atccagaaga cgagcgttat caagcgctca tcggcaaaaa agtgattcta cctttagtca
    14101 ataaacaaat cccaatcatt gcagatgaat atgtagatat ggaattcggg acaggtgtag
    14161 taaaaatcac tccagcacat gatccaaacg actttgaggt aggtaatcgt catgatcttc
    14221 cacgcgtaaa tgttatggat gatgatggta cgatgaatga actagcagga aaatatgctg
    14281 gaatggaacg ttttgctgct cgtaaagcaa tcgtgcaaga tctgaaagaa atcggtcgat
    14341 tgattaaaat cgatacgatg atccacagtg tgggtcattc cgagcggaca ggtgtcgttg
    14401 ttgaacctcg gctgtctact caatggtttg taaaaatggc gccgttagcg aaaaaagcca
    14461 ttgataacca agaaacagat caagcagtgg aattcttccc tccaagattc aatcaaacgt
    14521 ttttacgttg gatggaaaat gtccatgatt gggtaatctc acgacaatta tggtggggac
    14581 atcaaattcc tgcatggtat cacaaagaaa caggtgaaat gtatgtaggg atggaagcac
    14641 cagcggatag tgaaaactgg gtacaagatc ctgatgtttt agacacttgg tttagttcag
    14701 ctttgtggcc tttctcaaca atgggctggc cagatacgga aagcgaagat tataagcgat
    14761 acttccctac tagcacttta gtaaccggtt atgacatcat tttcttctgg gtaagcagaa
    14821 tgattttcca aagcttggaa tttactggcg aacgtccatt tgagaatgtc ttgattcatg
    14881 gattgattcg tgacgaacaa gggcggaaga tgagtaaatc attaggtaat ggaatcgatc
    14941 cgatggaagt aatcgaaaag tatggagcag atgctctccg ctggttctta tcgaatggtt
    15001 ctgcaccagg acaagatgtc cgcttcagct atgaaaaaat ggatgcttct tggaacttta
    15061 tcaacaaaat ctggaatgct tcacgtttcg ttatcatgaa tatcgaagga atgaccgtag
    15121 aagagatcga tttatctgga gaaaaatcag tggctgaccg gtggatcctt actcgtttga
    15181 atgaaacgat cgaacgagta actgagctat ttgatcgttt tgaatttggt gaagcaggtc
    15241 gacaactgta taactttatc tgggatgatt tttgtgactg gtacatcgaa atgagtaaag
    15301 aagtacttta tggagatgat gctgtttcaa aacaaaccac ccgtagcatc ttagtccata
    15361 cacttgatca gatcctacgt ttattgcatc caatcatgcc attcgttaca gaagaaatat
    15421 gggaacatat tcctcatcag ggaaattctc tagtagtggc agaatatcct gttgtacgtc
    15481 cagagtttga tgatgaaaca gcttctaaag ggatggaagt attgaaagaa ttgattcgag
    15541 ccgttcgaaa tattcgttca gaagtgaata caccattgtc taaaccaatt acgttgctaa
    15601 ttaaaacaaa cgatgctaaa atcgatcaat ttttagttga aaatacaagc tatatcgaac
    15661 gcttctgtaa tcccgaagag ttgacgatat caagtgagat cactgcgcca gatctagcga
    15721 tgtcagctgt tctgacaggt gcagaaatct tcttgccgtt agcaggattg atcaatattg
    15781 aagaagaaat caaacgatta gaaaaagaac tggaaaagtg gacaagcgaa gtaaaacgtg
    15841 tccaaggaaa actttctaat gaacgttttg tttctaacgc gccggaagaa gtagtagagg
    15901 cagagcgtgc aaaagaaaaa gattatttag agaagcaaac ggctgtcaaa gaacgaatcg
    15961 aaagtttgcg tactattcaa taagaataga aaaagagagt gtgaaatcag ctagctatta
    16021 ctaaaagcta gctgattgaa catcgttaca ggaaagagtt tgagcctcac tcttagcttc
    16081 gattcataag gagatgtgac ataaattttg tcgcatctct tttttagtct actcttatta
    16141 tgtaggagaa ggagggaggt ggatcatgta tcaagagtca ataaagtagt tgataaaatc
    16201 gttcctctct ctgtttcttt tctctttgtc atacttttat ttttcttatg tgttctattt
    16261 gttataataa aagagaaatg ggggaattgt tgatgacgat tgaagaagca atagaatgga
    16321 tccatagtcg attaccattt ggttcacgtc ctggccttga ccgagtcgaa gctttattag
    16381 aagtggtagg gcatccagag agaaaagtaa aaacgatcca tatcgctgga acaaacggaa
    16441 aaggttctac tgtagcttat ttgagaagcc tattagaaga ggctgggctg acagtaggta
    16501 catttacttc accttatatc gaaacgttca atgaacggat cgcaatcaat ggcaaaagca
    16561 ttccagacaa tgatttgatc cagcttgtaa aaaaatatca gccactgatc aaacaacttg
    16621 atcaatttga agcagtagct ggtattactg aattcgagac attaacagca atggcatttg
    16681 attatttttt gatgaagaaa gtggacgtag cgattatcga agttggctta ggcggcttat
    16741 tggattctac caatgtagct gtaccaatgc tgacgggaat aacaacgatt ggacttgatc
    16801 ataccgaaat acttggagat acaattgaag aaatcgctgc acaaaaagct ggaatcatca
    16861 aacaaggcgt tccagtagta acaggaaata ttgccccaga agcttttact gtcatccaac
    16921 aaacagctaa agcaaaaaat gcaccgcttt atgtatacgg ggaaaattat aaaataaact
    16981 atctgcatcc tgatgagatg tggggagaag tatttgaatt ttttaatgaa ataggaaaga
    17041 tccctcaatt aaccactccg cttttagggc aacatcaagc tgaaaatgca ggagtagcca
    17101 tcgaattgta ttttgtttac tgtcaattgg aaaagctgcc tttccgagaa aaagatgttt
    17161 tgaagggatt gaagaaatct cgatggccag gaagaatgga gcgtttgagt aacgagccat
    17221 tagttgtttt agatggtgcc cataatacgc atgcaatgaa ccggcttgtt gagaatttga
    17281 aaaaagaatt caaaggatat caaatcaaca ttttgttttc cgccttacga actaaaaatg
    17341 ttagagaaat gctagaacga ttgcagcaag taccaaatgt ccatatttat ttgacgacct
    17401 ttgaacatcc aaaagccatc gaattaagtg aagtatcaga tttagcaagt gagagagtat
    17461 caatcgtttc attgtggcaa ttcggattag cagatatatt ggaaaagatg acaaatgaag
    17521 acgtattagt tgtgaccggt tcactttatt tcatttcaga agttcgccat ttattaatac
    17581 aattaggagg agatcatgaa gtataatgca gtgatttttg acatggatgg tttgctgttc
    17641 gacacagagt tagtgtatta cgaagccaca caagtagtag cagacaagat gggttttcct
    17701 tatgataaag acctgtattt aaaattctta ggtgtttcag atgaagaagt atgggcgaat
    17761 tatcatatga ttttctcgga atttggcaaa acaagtgtac aaagattcat agatgattca
    17821 taccaggaaa cgcttgaacg tttttcgcaa ggagcggtac aaatgaagcc cggtgtgttg
    17881 gaactcctct cttttttaga agaacatcag attcccaaag ttgtcgcttc cagtaaccaa
    17941 cgagcagtca ttgaactttt attgaagaag aacaatctgt ttgaacgatt tgagacgatt
    18001 gtttctgcag aaaatgttca acgagcaaaa ccagacccag aaattttctt gttagctaat
    18061 cagaagctag gtacagcgaa gaaagaaaca ttgattttag aagattcaca aaatggtatt
    18121 ttagcagctt ctgcggctga gatcccggta gtcatggtac cagatctgct tccaccatcc
    18181 caagaattga tcaaaaaaac agctggggtt gtttcttctt tacatgaaat ccctgcattg
    18241 ttaaaataaa aatccatctc ttttcgtatc ttattttaga taagatagaa aggagatgtt
    18301 tttttgggaa aacgattgat caaagaagta cctactagct ctttaccaag ggaacgtatg
    18361 gaaatttatg gcgcggaagc tttatcggat caggagcttt tggcaatctt actgcgtacc
    18421 ggtcaacacc cttatagtgt gatgtcgatt gctggaaatc tgttaaaaac gtttggagga
    18481 ctggcctctt tacgacaggc tactttgcat gagttagaag agattcgagg gataggacgc
    18541 gtgaaagcaa tcgaaatcaa agccttgatc gaattaggtc gacgaattca gacggatcat
    18601 gaaagagcgg ctccaccggt tcgtaccagc tacgaattgg cccagcaatt gattctggaa
    18661 atgaaagatc acaaacaaga acatttggtt tgtatttatt tggacacgaa gaatcaagtg
    18721 atcttaaaaa aaacagtgtt catcggttcg ctgaatcagt cagtcgctca tcctagagaa
    18781 attttccatt atgctgtacg ttattgtgca gcaaggatcg ttttagcgca taatcatcct
    18841 tccggaatat ataagttagt acacataaat tatataagga aatttactgt tatattgcca
    18901 tctggaaata ctattatgtt atcgataatt gaacgccata atgcattttt ttcttcttcc
    18961 gaagattctt tataaatttc atcgaattct tttgatagaa taaattcgac attttttata
    19021 tctattttag ctggctctac ttcaatttca tttaattctt tcattaaagc ttctcgatct
    19081 tttttgtatt ccgctaagtc tataacttca ttcaagtagg ctttcttcaa tctatctaat
    19141 ttattctcaa tatttttctt actatttttc tttttaataa tctttggttg tttttttgaa
    19201 tagtttattt gtatttgttc aaatttttgt ttagtagctt caaaaatata acgttctaaa
    19261 tttttttcgt aaaaagcgcg cttatttgtg caacgtaatt tattatttct tcgttttaca
    19321 catctataac aagtcctttc gtatatagat tctgtaccgt cttttttctt atatcttgct
    19381 ttaatagttt gaccagctac tgatccctga cagtcagaac attttaataa acctttaaaa
    19441 atgtaatcac gttttgcatt tgtttttaaa tttttaggta aggctttttg aacagcataa
    19501 aaaagttttt tatcaataat aggaggacag taatttttat tatttcttaa ttcaccaatg
    19561 tattttttgt tcgtcaacat atttttaaca ctttgataat ctctaacgat tccatactga
    19621 gagcctaaat aataaacagt ttttcttaaa ctaccactag aaagaaagta gttgaatata
    19681 tctatcacga taggagcatc atcatttatt actaatttct tattttctat agagtagcct
    19741 aacggagttt tcccgcttac tacttcacct tgtgcaattt tatttgccat aacagctttg
    19801 atgcgttctg aatcaatttg ggcttccaat tcagcaaaac tcattacttg tgcaatgaaa
    19861 gttctgccat acgctgtagt tgtatcataa tattgttgag aaacagcatt ccaagaaaca
    19921 ttgtgttttt ctaaaatttc ttgagtgttt aaataatgtc gtagatttct aaaccatcta
    19981 tctaattttg taaataaaat tagatctatt ttattttctt ttacatcttg taatagtttt
    20041 tgaaattcat cacgatttat tttttgacca gaaataccac cgtctacata ttcattaact
    20101 actttcaaat ccttgtgttg ttcgatatat tcatagaggg tttctttttg ttctctaaga
    20161 ctatctccat gtttggcttg ttgttcagtt gatactctca tatataatgc tactcgtttc
    20221 atgttatctc ctttcgaatg tatgttctta tcgttgtaaa agaaaagccc gaaggctaat
    20281 ctttttacta cacatctgtt aattctaatg atcttctgta ttgttcagct tgagctagtt
    20341 tagtaaaaga tacagttccg ttataatttt ctaaaacaac tttttcaatt tcatcaagag
    20401 atactttaaa gaattctttt cgttgattaa ctttattgac ttcgtttttt ctaaaatgcg
    20461 aatgtagttg attttctaat gttggtgcat cttctgaaaa tatcattgca tgaacatcaa
    20521 attcaaaagg tacagaagcg ctactaagtt ccttaattct atccataggt tctaaccgtc
    20581 tagtcattcc tattttatag acatcttcac cgaaagatcc gatattactg atgacataaa
    20641 catagccagc tctagtatta agttctcttt gcaatacatc ttctttgaca gtttctagtt
    20701 ctcttaattt ctcttccagt tctttaattt tatcagcata gagttctttt tcaacatcag
    20761 cactagcttt ttgcatgtat gccattaact tagttatctc tgagttaaac tgtcgttctt
    20821 ctttatcaat gcgtttcttt tcacgttcta tttcacgtct taccttttct tcttcaatca
    20881 tttgttcttt tattgctttt tgctgttctt tttcatcgtt aactttaact atgtatgaat
    20941 agttgagttc taattcttga agttttaatt caagtaattc ttttttgaat tctgcttcat
    21001 cgtttttaaa aagcttgttt attttatcaa aagttcttat aattttttct ctagttgaat
    21061 ctacgttaga aatagtaagt ttattgagaa gtccagttat ttctgattct aatggtataa
    21121 gcattttctt tttaatatta ttagcttctc tattattcaa ataagaagga atattaattg
    21181 caccgtctaa aataaaatcc ttttctttaa tctttaataa agaaagtttg ttttttattt
    21241 cggatgaaga agtttcatct atattcggaa taattactga tttatagata gtgaccagag
    21301 atgtgtcata tttttgatta atttcatcgt ctaaccgctg gctttcagca ttaagaatat
    21361 caattttgtt ttctagcgtt gacaagtttt tattcaattt acttatgttt ttctcttttt
    21421 cagatataaa cgtttcccta gcatttaatt cttgagaata ttcctttacc ttactctcta
    21481 aggcagaagt tttatctttt aattttttag cttcagataa tttgctacta cccataatta
    21541 ttaaaactat tccaactaaa aacaatagta ctcccattca aaacgcctcg cttcttttat
    21601 aaaataattg tcaaaatcat ataaaccctt accgaagttg acggctccgg catgggaatt
    21661 tttttaaaat acaacttttc cgataattct aatctgttct ggcgatacaa ttctatcttc
    21721 gtataagtcg tttatagaac gtaaaatgat tgtttgattt tcgtaatctt tatatatctc
    21781 tttacatgta actccgtcac cacctaattc cacaatagca atttccccat cttctacgtc
    21841 cggttgttct ttaacgaata cgaattgtcc attcctgata acaggttcca ttgaatcgcc
    21901 tataataggt actgcgaagt cagcagcact tggaactctc tcaaattctt cctcttcgac
    21961 aaccgtatca ccgtaagtaa gttctgttgg attggcagcc gaagccgaat tgtgaacagt
    22021 tgggattttt tcttttttag gaaaatctag gacattttct tgtttttgtt cttctaatcg
    22081 attacttgca aattcatagg tagcaacttt attttcgtcg ttaagctgat tatatatagg
    22141 aaggatatta tatatctgat tagatataga taaatcaata ttcatcaaat catctatatc
    22201 aacattgaat atcttagcta tctcatttaa ggtttttaat tttggtgtat attttccttt
    22261 ttcccattcg cttattgagg atgaactttt tcttcctagt ttttcggcta gttcttgttg
    22321 atcaatatta tacttttctc taagaaactt tagattttca gcgaacatag taacacctcc
    22381 ttgagttaat tgtaacaccg tttcggaaaa aatgtaacag gtttcttaga aaatatttta
    22441 gtgtttttaa agaagtattt acgcaaaata gaaatcgatt tcaggaaaac tgaaatatgc
    22501 acttgacttc ggaaaaaccg aagtatataa tttagtcaga aagttaaaga gaggaggcga
    22561 ataaaatatg gataccgcga agaaagaaaa atatacattg agacaattaa gagctttaaa
    22621 gggttattca aaagaagaac tgtcaaggaa aagcaaagtg acatcaagaa caatatttat
    22681 ttacgaaaac gatgtagata aaatgaggaa cggaaagtac gccactctag aaaaaattgc
    22741 taaggcattg ggtgttagag tttccgatat ttttttagac cctgattcgg aaaaaccgaa
    22801 atcaataaca ggtgaaacaa aacaagtcag ctaggaggtg tgaatagtgg aagagaagaa
    22861 tataaaagta ccgactcttg aagaatatac aaaaattgtt gtcgaaacag acgagcagaa
    22921 cccgaaaaca atcgcagtta ttacggcgaa tgatattgaa tcatgcgaag gttttcgagt
    22981 tcgaatgacc cctagatatg attaatgttc tttatcacgt ggaggtatag gatcgtttcc
    23041 aaaactatct tttgattgta tttgtccatt ctttttttgg acaataaact ctgattgctg
    23101 ttttttagaa atctttttac catactcaac agcatctgat ttattatcaa atagttttgt
    23161 atcttcggaa ttaccttcac cacgtacagc ccatttgcca tttctaggag atacccattg
    23221 atttttaccc ataacaattc acctcgcttt caagttaatt ctattaagag gtgaaaagaa
    23281 aacaaactga tggaggtgag attgtgagta acaagccaaa aatcactttg aatggcacac
    23341 ctaatcttca aagattagca gatgaaatgg ctagaatacg ttctagacat tggggagtta
    23401 ctgtggtggc aaccataatt gaacaaaaag aaaagcccac acagccggca agcaagtagt
    23461 gggcaccata gaacaataat attatatcac acactcgcca cttccgaaaa gaggagttgc
    23521 tgctctcctt tcaagtttgc caaagtccac gtttcttcat tttggcaact cctcttcttg
    23581 gaggtggtga cggcgagaga cgaaggaggg atgacatgaa ggaagaatca aaaataggga
    23641 ttttgaatga gaacaattac acaagattaa ttattgaaac agaagaaggg gaaaaagtag
    23701 cagaagttac attgaccgat gcaactcctg ctgacggtta tcgtattcga ttaactccta
    23761 aatatgatta accttttggt gggtgtggat cgtttccgtg actatcacgg ctttgaattt
    23821 ttccatctct gccatgaata aatagctcag atccttgatt tttagaaatc tctctagcga
    23881 tttttactgc ttctgatttt gtattagtat gtgcagtcgc tttagaattt ccagcacctt
    23941 tgacattcca accaccattg gaattaggta caacatgttg attttttccc atagttttca
    24001 cctccatttc tatagaaata ttttatcaaa tagaaatgga gaaattcaat aaacgaaagg
    24061 agggatcaaa tgacattaca agagcatcaa cacttgatgc gaaaactaaa tcaggaatac
    24121 cacgaggaaa tgaaacctag attgctaggg gaacaatggc gtgaacgcca gaagaagtgg
    24181 ttagaaataa aaaagtgact cagccgtcca aagcaatgag tcacaaacca aaaattatac
    24241 ctaaggagat tttatcacat gaataagaaa attgaaaatc ttatcgaaga attgaaacgt
    24301 gaatgccaaa agcaaggtgt ttctattatt tgtacagccc aaaaagaagg ggaacttaaa
    24361 agtctcgttt atggtgagac aacagaaatt ttactttgtc ttgctatgca agaagaacat
    24421 ttagatgaaa atctcccatt gtcagcacat attatgcgta gaattgctgt ggatgcttac
    24481 gaacaagcga aaaatgaaga agaaaatcaa ccttcaaatc atacttttgt tattaataac
    24541 aaggaagatt tagctgatgt gatgactcgt attctcaagg gggaatttca atgatgaatg
    24601 aaaaaacaat tgatctactc attattttat ttttcacgtt agtgattgta gcgaaaagtt
    24661 atgtaatctt tggcttgtta ttcgcaatta ccatgcttgt gctttgcgtg ttagcaagca
    24721 gaaaagaggt taaacatgaa cgagttagca aatcttgaca actatttaac tgatcctgat
    24781 tatgctaaac caccatatga agcgccaatt gatgaggagg atgaagatga gtaaatctac
    24841 cttagaaatg agccatcaag aatggctcga agaccgcaaa agaggtattg gtggctcaga
    24901 tgttgcaacc gtacttggat taaacaaata caaatctcct tatcaattgt ggcttgagaa
    24961 aacgggtcaa attgaattga aagatttaga aagcgaacca gcttattggg gtaatgtttt
    25021 agaagaagtg gttgctaaag agtttcagga acgtacaggc aaaaaagtac gcagaagaaa
    25081 ccaagtattt gaacatccat tacatccatt tttaagagca aatattgatc gggaagtagt
    25141 gggagaaaat gccattctgg aatgtaaaac agccaatcaa tttctcggaa aagagtggga
    25201 aggtgaagag gtaccgctta gctatctctg tcaagttcag cattacatga acgttttaaa
    25261 caaagactat tgttatatcg ctgttttgat cggtggacaa aaattcattt ggaagcggat
    25321 tgaacgagat caagagctga tcgatacaat cactgaacaa ttagtagagt tttgggaaac
    25381 gaacgttctt ggaggtatcg agcctgtaat tgacggaagt ggagcgactg ctgacttctt
    25441 aaaagaaaaa tatgcagatg tagaagaaaa tcaaacagct ctaccatcac gttttgatga
    25501 acttatcgag caaaaaagag aactcaagcg gacgaaaaaa gaaattgaat catctattcg
    25561 tcaagtagac aacgagatca tcagtgagct aggtaaacgt gaagccagta tcggtatcac
    25621 acaaagaaac attatcagct ggaaacttgt tcgtacaaga cggatgaaca cgaagaaact
    25681 agcagagaaa tatccagatg tcgcaaatga tgaagagatt tataacgtta ctgaatcaag
    25741 aaggctaacc gaaaaggaga tcaaataata tggcaacaaa tgaatcgtta aaaaatcaat
    25801 tggcagaaaa gccacagaaa caagttgcac caggacagtt agggcttaaa gctctaatga
    25861 atacaccaac aatgagaaag aaatttgaag aagtacttca tgacaatgct aatgctttta
    25921 tgtcgaatgt tatgactctt gtatctaatg acagttatct tgcagatagt gaaccgatgt
    25981 ctatcatgag tggtgcgtta actgctgcaa cattaaatct tgggctagat aagaatttag
    26041 gttatgcata tttagttcca ttcaatagta aaaacaagca aacaggaaaa tgggaaaaga
    26101 aagctcaatt catgcttggc tataaaggat atatccaatt agcccaacga tcaggtaaat
    26161 acaaagcatt aaatgtgatc gaagtttacg aaggagaact aaaaagctgg aaccgactga
    26221 cagaagagtt tgagtttgat ccaaatggta gaacgtctga tgaagtcatt ggatatgttg
    26281 gctatttcga gttactgaat ggattcaaaa aaactgtcta ttggaccaaa caagaaatcg
    26341 aagctcatcg gattgctaac aataaagatc gcgataagac aaagttaagt ggtgtgtggg
    26401 catctgatta caatgcaatg gcacgaaaaa ctgttttgag aaatcttctt tctaaatggg
    26461 gaatcttgtc catcgaaatg caagaagcca ccacatcgga tgagagagtc caaagggttc
    26521 aagaagacgg cagcattatt gctgaaacag aagttgaaga agatattcct gaaagaaaag
    26581 aagcagaggt tatatctgaa gaaaatgaag atgtacaaac tggattattt gatgcatcta
    26641 atccgccgtt aaacaaataa tgagggagct ttctcccttg cttttctaga ggagaaatac
    26701 gaatgaacac aggatatgtc aaattacatc gaaaagtgat gaattcattc gtttggacca
    26761 atccttatat gtataaatta tggagcttgt gtttgatgaa agcgagtcat gagaatcgca
    26821 agatactttt taatggaaaa gagatacaag tgaacagcgg agaattcgtc acagggcgcg
    26881 atgctatcac atctgagatg aacgaaggcg tgaaacgtga acatcaagtg aacagcggtt
    26941 ctgtatggag atggctaaaa caatttgaaa aaaacggaat gttgaacatc aaatcaacta
    27001 cgaaatacag cgttatatca ataaaaaact ggtctttgta ccaaagcagt gaacaacaaa
    27061 tgaacatcaa acgcacaaca agtgaacaac aagtgcacac aaacaagaat gaaaagaatt
    27121 ataagaatga aaagaataat aaaacatcat cgtcgcaacc acgcaaaaag cgtgtttacg
    27181 acaccgactc agtttactac attctcgcgg aggagttatt caaacagatt tgtcagaatc
    27241 aggaaatcaa aaagccgaat ctgcaaagtt gggcagataa cattcggaaa atgatcgaga
    27301 tcgacaagcg gaccgaaaac caggtacggg gaatgattga atggagtcag cacaatgtgt
    27361 tttgggcatc gaatatttta tctgctaaaa aattgcgaga aaaatacgac acaatggcag
    27421 cgcaagcaaa tcgtgattat aaaacaaaac aaactaaaac gcttgaatac gagaaattta
    27481 gcacagatga gttgcctatt tgagaggagg cgtaggcatg gaaactgttg gggaaatcat
    27541 ggaaaagctg atacagaaag tgcttgtcca acgtggcgaa tgtcctgaat gcggacagcc
    27601 tttgtatgga tggcgtacga agaaccctga tggctcagaa cgttgtaagc caacctgtat
    27661 gcaatgtggg tataaagcat tgcgagttca ggaagactta caaacagaac gaatttacaa
    27721 cgagagcctg aaagcaagag caatcaattt tttcaaaggt ggttctgttg tgcctaatca
    27781 agcgttgttt gattgcacat tgcagaatta tcaaattgtc gatcaagaaa caagacaagc
    27841 ggttgaagta accaaacgct ttgttaattc agtcttgtta ggaaatccaa gtcaccttgt
    27901 tttaactgga aaacaaggaa caggtaaaag tcacctagcg atggcagcgg cttgggaagt
    27961 cttgaagcga tcaaactacg ataaaaaaat cttatttatc gggttacagg aaatgctgga
    28021 tcaaatcaaa ttttcgtaca acaatcctga actcagaaaa acgattgagg gatcgttgat
    28081 tgcagatatc aaaacagcgg atttagtcat cattgatgat atcggttcag aactaggaaa
    28141 agatgcatca gatagtcgag cgtttggcat aaacacgcta aattcgttct tggatgcacg
    28201 acagaaccta gcaacgatta tcacaacgaa cttgcttggt gaagaactga aaaaagctta
    28261 cggtacgaga acaatatcaa gaatgtttgt caactctgat ggatttacga tggtattttc
    28321 tcaaacagca gacaagcgca taaaaccagt gaaaggtagt atcgcatgaa taaataccgt
    28381 aataaaaaaa ctgttcatcg aggtatcaag tttgattcta tcgcggaagc agagtattac
    28441 gatctagcct tgtggcaagc tgaagcgaat ggttggaaag tgaagctcca ggaaaggttt
    28501 gagctgatgc cgaagtttga actagagggc aagaagtatc gcaagatcga gtatattccc
    28561 gacttcacat tttacaaaag cggcaagctg gtcaaagtcg tagatgttaa ggggatgcag
    28621 acaaaagact ttaagatcaa ggcaaagttg ttctgtcatc aatatcaagt gccgttgata
    28681 ttagccaaaa aatatcggaa tacgttcaag gaagagcgtt tttaacgagg tggtccatca
    28741 tgacaacaga agaagtgatt caaatgcgaa ttcgaagcct tcggcgtgag attgacgatc
    28801 tggaacgaac aaaggcagtg atggtcaatg aaacggctag aaaggcaatc gatttgcaca
    28861 tagagaattt aagaagggaa atccgtagat tggaggaatg agcgtggata aggaagcggc
    28921 ttggcgaaaa ttaatgttgc tgattcaaga tgagaactgg caagaagatg aagcagtggt
    28981 tgctgaagtt cagcgtctag gaaagattgc taacggacgt atacgaaaaa agccagacaa
    29041 aagaaaacag cgcaaaggga aaatcgtcgt tgttttacac gaaggcaaaa ttttgatgca
    29101 aggaacagct agtgagctgt ctgcagaaac tggatatacg cgtgggacta ttcgaacgta
    29161 cgcttggcga aatcacaccg atcgaaaagg gcacgaatat aagtatttgg aggaagaaaa
    29221 atgaacgaaa acaaattaat caaattgggt gtagcaggag cagtaatcgt aggtattgga
    29281 gttatcggag gatttaagtt cttcgaaaaa atcgataatg gatatgtggg tgtgcgctat
    29341 tcaatgaacg gcggtatcaa agatgaagca ctgacgcaag gtgtgaaatt tgtagggatt
    29401 gacaaagtga tccaatatcc aattcgcttg caaactatcc aatcaaaaaa tatttcagta
    29461 tctacaagcg acggcaaaaa gacaacgatt gatatcaaat atgactacaa agttgattca
    29521 actaaagcag caaaaatgta caaggaattt gggaatatca cttcggaaga tatcgaaagt
    29581 ggatggttaa aatctaagct tcaaaaggtc gctcgtgaag tttatgcgaa atatagtctg
    29641 cttgatgtcc tttcaggaga ttcctctaaa gttgaagctg aggtattaac gaactttgct
    29701 aaatcagttg aatctaaagg gtttgaagtc gaagacgtaa cacttggtgt tccagatgtc
    29761 gataaagaaa cacaaaaatc aatcgatgcg atcattcgag ctggtcaaga aaatgaaaaa
    29821 gcgaagctag acgcagaaac tgcaaaaact caagctgata gtgaagctta caagaaaaca
    29881 aaagctgcag aagcagaggc agaatctaat cgcaaagtcg ccgaatcagt aacagacaat
    29941 ttgattcgtt atgaagaagc tcaagctcgc aaaaagcatg gatgggtaac agtaaatgga
    30001 gcagatactg tagttacgga tgaagcaggc aaataatatg ggattcttta tggctaaaat
    30061 tctcttgttc ttaggtttag taggagcagc atatctcgtg tatgcgctcc tttcccaaac
    30121 tgatgacaaa gaagatgaca acaacgatga aatgaaattt taggaggaga aataatggac
    30181 gaactaatca caaaagtaga gcagtgggct aaagacaagg gactggatca agcagatcca
    30241 aaagcacagt ttttgaaagt agctgaggaa ttcggggaaa tagcttcggc gatggcaaga
    30301 agtaatgatg aactatttaa agatagcgta ggagacgtta tcgtcacgct gattatcctt
    30361 tccatgcaaa aagggacaaa cgtacaagag tgtttagaaa tggcatacaa cgaaatcaaa
    30421 ggacgcacag ggaaaatggt agatggtgta ttcgtgaagt cgagtgattt ggaggatgtg
    30481 aaatgaaata cgaaatacca ctaagtgaag cgggcattca agcaattatc aatggtcggg
    30541 aggttaacat agaacttcct gatggtactg aattagtcat cagacaaagt tatttgaaag
    30601 atatggcagc tccagtatta attgatcgtt ttaacgtgac tgattctgtg gtagagaacc
    30661 acttaaaaga atttcgatca agtatagacg acactttcag attagggagt tgattgacaa
    30721 tgaacaacag acatcgcaga ataacaaaac taagaaaaca ggaactgaat gtactaaaga
    30781 caaagtttga aaaagaatat ggaatttcag cagaagaaac atataaagtg gcaagtcagt
    30841 ttgttgctga tgcaagtgat gctattcgta agtttgggat ttcgatatta aatgatgatc
    30901 gtaaatggga ggaaatgaga tgaaactaaa agacggattt tacgctagta gtcacggcat
    30961 cggcggttta atgctagata tgccgacaaa gaaccctaaa acacgtaaga aaccaaaagt
    31021 caaagtcggt gacatggttc gctgtgaagc agaagagttc atttatccgt ttcgtggata
    31081 tgtagaacac gtctataatc actcagcgat cattcgtatt gaaaacacaa tggaatgcga
    31141 taagtggtta gcgaaaagca aagagaattt agctgtagcg agattggtgg atatggaggt
    31201 tataaacaat gaagtttaaa atctttgaag aggacactcg ttataaatta gaaaaagaat
    31261 taaacgattt tgcgaaaaac aatgagattc agcatatatc tttagcaact tctaagagag
    31321 gttatgcaaa ttactatgca gctgttgtga gctatgtaag tcgagaagtg taactcggca
    31381 aataaaaaaa gccggatcgc tccgactgat tcaataaatc caacacattt attatatcac
    31441 ataaaggagc ggtttgactt gatgcaattg ttacgagagg tagatttcaa acagacaaga
    31501 tgtaatgcga gagatgtgct gaagaacttt cggcgtttgg agcggatggc aggtcgctct
    31561 ttgatagata ttaagtcgcc gattattacg gatatgccga aggcaccgaa gcacggcaat
    31621 aaggcagaag acgcgatcat tcaaatgatg gatatagaag cggagagaga cgcgattcta
    31681 gtggctttga tggctcttag tctgattagt cgtcagatac tctactacag cttctgtgtg
    31741 ccagacagct tctcaaacta cagaattagc cgtgaagtgg gttattcaga aagaagtata
    31801 caacggatga aatcggaagc tctaatagag tttgcagaag catataaaca cggaagaata
    31861 attgcttata aataggggga ccatataatg tggaaagatt atgtatcgtt gaaagagttg
    31921 aaaaaagatc ttgttttcaa aagaattgta gaatggtcag agagtgaatt aattttagaa
    31981 gatggaacca aaatggaagt tgtatgtagc gaatcagatt gctgcgcatg ggccgaaggt
    32041 gaattcaaaa atgtaaagct tgatgcagtg attacagata taaagatttt tgataaaggt
    32101 aaccgtctct ataatggtga cggacatacc tcttatgctg aagtcgttgt ttatcataat
    32161 cgtaatgaga tcgctaaagc agaatgcaca gcgaatgatg ggaatggcgg ctactattat
    32221 agtgtttgtg ctttaaaggt caaagacaaa ctttgtatag tgactgacgc ataaaaaaat
    32281 ggcggttttt tggcggaatg atggcggttt ttagccattt atcagtgata ttatggtagt
    32341 gtcgaaagat tagtgatagg tctgagacaa aataataata aaaggaacat cgttttatta
    32401 ttgtttcaca attaagcttc gatagacagc agcggaaata ttaagaataa ggatgtgaat
    32461 tttaactcct tctaaattgt tcttattatc tatcatccgt tgctgtctat tgttacatac
    32521 agatcgctta ggcggtcttt ttattttggc cgaaaaccta cattttcgat ggccgattat
    32581 tggaggagga atagcatgtt caaactatct gaaatcatta agaagtccga cgttgagaaa
    32641 ttagagatgt taaaaaagaa gttgaagaaa tagcagtctc ttcgtgaggc tgttttattt
    32701 tgctcacaaa aatagaccac tatcgggtaa tagtggtcag gaattaaatg aaaaagatgt
    32761 tagggttgtt agctaagtat aacatcataa cgcttacaaa acaatgcaag aaggataaat
    32821 tattatgaga acttactggt atgtgtcatt aaacaataaa tatccgaagc caatgaaagg
    32881 acagcatagg cgtgtagtca tgtctgttca aatgaaggcg aagtattcga ttgtagaaat
    32941 gatcagagag gcaacgccag tagagattga ttattgcaag ctagtctatt gtgggtgcgg
    33001 ccgttggaaa gaggatcatg tacaaaaaaa tatcagcaag tacatataga gaggcggtga
    33061 ttaaggatgg aaaaaagcga tacgaaagcg aacagataca aacctactgc tgcagagaaa
    33121 aaactcttgg aagtattgat aaatccagat aacttaggca aaccggtgca agagttgtgt
    33181 tcactggcga aaataggtag gaccaaatat tacgacgcca tgagcaaaga tggctttgtt
    33241 gatctagtta acgaaacaac aatggatctg atcaaaggaa aagcttctga tgtccttaat
    33301 gccacttaca agtatgcatt gactgaaaaa ggtcatcagg ataggaaaat gattctgact
    33361 attgctggaa tctatgcaga caaacaagaa ctcaaacatt ctggcggcgt cgatatccga
    33421 aaacagtatg agaaaatgtc cgatgaagaa ttagaagagt tggtgaaacg gtatgaaaaa
    33481 atcaacgact cttaatcgtg ttgagtatgc cgttgttcaa agagagctag ccattcgaaa
    33541 agctaggaaa agtttttggc tattctgcca gcttctttat ccagagtttt acaaagatga
    33601 tcggttgtat ttgaaagatt tatgtcatac gctacaagat ttttacgaag ataaaatcga
    33661 caaaaaaatt ttggttatta acatgccgcc tcgacatggg aagactttta cagcgcggct
    33721 attcgtttta tggatgtttg gacaaaatcc aaagacgaaa attattaccg gatcttataa
    33781 ccaaatcctg tcatctttat ttgcgcaaca aacacgtgat ggaatcatgg ttgaaaacga
    33841 aaatgttaag gctgaatact ttaaagatat ttttccagag gtgcaaatca aatatggaga
    33901 tgctgcaaag ggtttctggt ctttagatgg ttcagaagaa aagaattatt tagcgacttc
    33961 tcctggtgga acatccactg gtattggcgc gaattatgta attgttgatg acatcattaa
    34021 aaccgcagaa gaagcctata acgagcgtgt tttagattct cactgggaat ggtataacaa
    34081 cacgttggcc caacgaatgg aacggccacg taaacagata ttgattatga cacgttggtc
    34141 aagtaatgat ttagccggaa aaatgttgac gagacgaaaa aataatgttc atcagatctg
    34201 ttataaagca gtacaagaag acggctcgat gttgtgcaac gagattatga cccacgatga
    34261 gtacttagat gtggtacaag aaatgaatgt agatattgca gaagccaact atcagcaaga
    34321 accaattgac caaaaaggca ggctatatca gaagtttctt acttatgata cgttgcctga
    34381 taacattatc aaaatatgga actacaccga caccgccgac aagggtgccg attactttgc
    34441 gtctcctgtt tttgctgaga cgtctgatca tgatgcttat attatcgatg tcatgtatac
    34501 aaaagagccg atggaaacaa ctgaaatagc ccacgctaat atgattattc gcaatcgagt
    34561 taataaggta cggattgaag gaaacaatgg cgggcgtgga ttcagaagaa attcagaaag
    34621 aattacaaaa gagcgaggct atcgaggtgc agtatttgaa gactttcatc aatcggataa
    34681 taaactgtct agaatactgg cgaatagtgc ttgggtggaa aatcatgttt actatccaga
    34741 tgattgggcg acacgttggc cggactttta tgaggctatg gttagttatc aacgtgaagg
    34801 taagaacgct catgatgatg ctccggatgc agttacagga attgcagaaa cgattataga
    34861 agcagatgac ttcgagttta ttgcttatta ggaggtgggt ctttgtttta ttctggaatc
    34921 acattgaaaa aatacaaacg tttaagaacg aaatattcaa cgcaaatcga agaaggatta
    34981 ttcgatccta acgcttttat ggaagatatg aaaccctttt tcgatgatcg agaaagaaag
    35041 tatcttgctt atactagcga gaaaaacgag atcgacagtc gtgagaaacc aaaaacaaaa
    35101 atcattaagg tcaataacaa gattcatgcg ggaatgtatt cagtggtcgt tgatcaagca
    35161 gttaaccatt tcacaggaat accaattaaa tgggattatg atgtttcgga acagaaaagg
    35221 acattcattc aacgaatgag agacaaatta ctgggtaatg atatcagcgc cccttctacc
    35281 ccagaagaat ttgaaacact cacgagacaa ttaagtacta tgcggtttgg aatgttagac
    35341 cccgatactg caacatttca aggagcgaca gggcttgctt tcagattact ggagcctgtt
    35401 gagacaaatg atggttggga actaagagca agcaacattg agccgtggaa agctgaaaag
    35461 tacgaaaacg gcgcagtgta cattaaagag aaatacgatc catatcaaaa gaagttttat
    35521 gaagagatga aggttgtcac gccgaaatca atatttactt atgctcgata tactgattac
    35581 cctggcacgg tacaaggagc atttaaaacg ctgggtaatg ttcctaatcc tttaggcgtt
    35641 atcaatctta cggagtttaa aaacaataca aaccgttact gtgactttga agttgcagag
    35701 gagattagtg atgctattga tcgtgtttta tctgatcagc agaacgagat tgaacaattc
    35761 aagttagctt atatgctgat cactggggca gatttgtccg aggataaagc caagaagatg
    35821 atggagcaac tagggatcat caatctgaaa gaccctaatg cgaaagccgg ctacgtgaca
    35881 aaggatctac aaaaggattt caacgagtat cattttgatc ttcttaaaaa gcaattctac
    35941 acggtgtgta aagcaattga tttcaatgac gaagtcttta agtcgaatag ttctggggaa
    36001 gcccgaaagt ggcaaatcat tagtttagaa gctaagacaa ataccaaaga acagtacttt
    36061 cgagaaggat tgaaagagtg tgccgaggtt atggctgctt atttggattt tgccgagaaa
    36121 gttacaattg atccggaaaa gatcattttc accttctctc gttcgcttcc aacagattta
    36181 agctacctag ctgaggcatt gcctaagttg gcaccatacg tttctaagag gacgattcaa
    36241 agtcagatcc cgttcgtcac agatgttgat tatgaaaacg aaatgattga cgtcgaaagc
    36301 agacaatctt acccagacgg cgagtatgga ggtggcatcg ttgagtcaaa tagaaacgaa
    36361 gtactggacc aaacgtcgag aactggaaga tttagcaaga ctcaaaatgg aaaatcaaac
    36421 gctaaagaaa ctaagtagtg tctttcctga tgcgttgaaa gaaattcaag cggagttatt
    36481 atcccaagct gatttacacg atattaccta tgctgagatg atggaatttt atagtacaag
    36541 tgatcagaaa aaatatcgtg aatacgttga aaagaactac aaatcactga agatgtatga
    36601 tgcaaaatac aaagagttca tcgaagaata ctttccttct ttcgactacg ccaaagtgaa
    36661 tcggctgctt caaatgaggt cagatatttt tcgaattctt gcagagagtg caatagatgc
    36721 agatgtgaat aaatattttt cggatcggtt agaagatatc ttgcaacgtt cgtatgtatc
    36781 aaacgcaaac gtatttgccc agattttgaa cgtagatttg ccgaattact tatcaaagga
    36841 agaacttgaa cgttacctga actatccttg gtcaggtaag acattctcgc gtcgtttatg
    36901 gggcaatatt tcatctctag aacaaaagct atctaacgcc attacaacta gtgtagcaag
    36961 tggcgaagga gttctcgtgg cattacgaac aatgcgagaa gacccagaaa tatgcgatat
    37021 gttcaaaagg gaggaatcga agtacaacaa ggcgatcgaa aatcttgtga gaacagaata
    37081 cgctaaattc gctcaagatg gtattgagaa atcttatatt gaaactggcg tagacgaata
    37141 caatgtctta actgcaaaag atgaaaaggt atgttcaata tgcggtggca aagcaaagaa
    37201 caacccatac aagttgagtg aagcgatcat tggtgagaac cgtgcgcctt ttcatggccg
    37261 atgcagatgt acagatgttc ctaatatgcc gaaattagga aaagatattg acgaagagta
    37321 tgagcgttta tttggcgatt tattagatga gtttgcacat gattcttttg gaattaattt
    37381 gaaacggagg aagtagaatg aaagattttt ttgaagcagt actaacaatt aatgtaaatg
    37441 ctgatattgc agaagcctac aaaacagcta ttgagtctga gaaccatcct aatggcttga
    37501 gagaccattg gaatggcaat tatgcctacg tggttattgg cgatcaaact gttaattatc
    37561 aagataatac tccagttgat aagaataccg ttaatttaac gattcaatta ttatctcatt
    37621 cattaccaaa tttaaaagaa acagttgatt ggtatgaaaa tatgggatgt attgttgtta
    37681 gaactgacta caaagaagga aagtctagta attaggcttt tttattttgt ccgaaatgac
    37741 gttaaactag cgcaatactg ggcttggttg aatggtgggg cgcaactatt aaaactcaaa
    37801 gcaatgcggg gcgtgaaaac gaatcgtggg gcgaaaggag aatgattatg aaacacaaat
    37861 cattaatgcc aatgaatttg caatactttg ccgaaggtga cgatcaaaag ttttcttttg
    37921 atgacttcaa atcttttgtg gaatccaatg aagaagctca aaaatttatt cagtcacaat
    37981 ctcaaagtgt tgccgacaaa caattggaag cttggaaaca aaataactta gataaaatta
    38041 aacaggatac catcaaggaa tatgaggaat ctaagaaaaa caagtcacct gagcaaattc
    38101 aactggaaaa actacaagct gaatttgaag cagaaaaagc gttgcgtgtg acaagtgata
    38161 ataaagcatt tgttgcagaa caaattgctg gattagaact agatggagag ttaaaagagt
    38221 ctatttctca atttatgcta aataatcttg ttagttcgga tacagatttc actaagaatg
    38281 ctgttgaagg ttttacaagt gttttgaatg caattaatga gaaacatgca gatgcattaa
    38341 aagaactaca aatgaagtct gcatttggtg gaactcaaca atcgaataac caggttcagc
    38401 agaacaatga aacattaaca aatccagaag aacaattagg acaaattctt caacaattta
    38461 actaggagag tgaaaaatta tgaaaaaaac atctttaaat aatttagagt atttggatat
    38521 ttcaccagcg attaatgcta tgcaagtacc aaatacacct tttttaagct atttacttgg
    38581 tgctggaaaa acagagccag caaactcgac agaaattaaa tggcgtgaat atgatatcaa
    38641 caacgatgat tcttctgaaa aacttgaggg cggagaatat ccagatgctg aatcaggtcg
    38701 aacttggttt aacaactata ctgaaatttt tagaaaatca acctctgtat ctggtacatt
    38761 agatgctatt aatgtgaatg gagtcggaaa tgaattaact aatcaagtag cactacgtgg
    38821 tatggaaatg aaaattgatt tgaaccgaaa attgattact ggtgtaaaag ctgatgaaaa
    38881 tggttctaaa ggtcgtcgaa tgaatgggat tttgaacttg atcaattcag caaataaggc
    38941 agaaacagcc actgcgggtg cagtaacaag aaaagatatc gatactttat ttaaattgat
    39001 gtatgaaaaa ggttatatgg gagaaaaact atgcttgatt tctccagata tgcaggagtt
    39061 aatgactgat gagttagatg gaaaatcaac aaaaattgtt cagttcgggg aaagagtaac
    39121 ttttggattg caaattggaa atatcgtgtc taattacggt acaggtattg ctctactaga
    39181 accatcattg ccaaaaggaa caattgccgc aatcgatact aattatgtga aactacgtcc
    39241 attacgtgaa tggagagcag aagaacttgc aaaaacaacg gattctagac gtatcggtct
    39301 tgtaggtgaa tactctcttg aatacaatgc ttcaaactct ggggcaattt taaatttaaa
    39361 gtctgaataa aagggagtta gtactccctt ttttgatagg aggaattaca gtggtaaaaa
    39421 aagatgaaac taaaaaagat gaagtcgtga aatatagagt aggtaaaact aaaaattttg
    39481 ttgggtttgt tcatcctaaa actcgtagat ttatcacagc agattcaaat aacgaattta
    39541 tcatttctat agatgataaa gaagcaattg caattttgga agatgcaatt gatgttaatg
    39601 aaatttagga agtgatctga tggatgaatc gctaaaaacg gaaatcattg agtctacaaa
    39661 agaagatttt ccagatttga gtgaagaacg cataactaat ttattagaaa taattttgct
    39721 agaaattgaa tcatacaaca cttgtaaaaa tgatatttca tgggaaaagt taaaaagcgt
    39781 gattagtgaa gtgttgtata aaataataaa aaatgaatca gaaaaaacag tatcttcagt
    39841 tagacgtggc gatacaacga ttagttatgc ttcaacaaca aatgatgtta gtgagttact
    39901 tctaggctat ggtgatttga tacgaagagt tattggttgt ggaggattgg agttttttta
    39961 atgaatgaag cagatatttt agaaactact tatgaagata gttgtattat tgaaagactg
    40021 acggacattg aagattctaa tacaaatatt actattcaag attacaaaaa agtatatgat
    40081 aatcctattt cttgcgctct ttcacaaggt caaatcgatg gactagcagt catagaagat
    40141 ggagagatgg taaatgtttc aactgacaca tataaattat ttgttcatcc taagattaaa
    40201 ctaaaaaaag gagatcgaat aacaataact caaaaggcca gtggcttaat tttttctcta
    40261 tttgctacta agccttttta ctatcctagt cattgtgaag tgaatttgat aggaagtgag
    40321 aaaaatgggt aatctcaaat atgaatcaaa tgcagaaaag atcattgaga attttaaaaa
    40381 tatgactgta attgctcaaa aagaaggaat atccttcgtt aacgattcaa tgaataaagt
    40441 cgttagttta gctaaaccat taactcctgt aaaatcaggt aatttaaggc gaggatatcg
    40501 tgtagtaaaa gctagaaaac tatcaagcgg tcgaattgtt ggagcagtta taaacaatga
    40561 acattatttt aaatatgtag aagaaggtca taggactaaa aatggtggct ttgtcaaagg
    40621 gaaattcatg ttaactcgtg caacgaatct tgcaaatatg tcttatattc ctcgaagatt
    40681 taaacaaatg gcaataaaaa tcgttaagaa aggaaagtaa catgaaagat gaaatcattg
    40741 ctgcaatcag tagcaaatta aaagaaatct atcctgatgg gacaatatat cttgattcag
    40801 ttatgcagtc aactaaagat ttttatttcg ttttatcagt aatggaatct ggaactgaaa
    40861 atgtaggaat tgatattcaa aatgtttctt tcttaattga tattgcattg attgataata
    40921 aacctaatag aaatttaatt aatgaattag tctcacgttg tgggactttt tttaatacga
    40981 ttacaatcga tgagcaaata ttatttccaa aagcctattt acctgatgaa gcagatggtg
    41041 ttcaacatat tcgttttaca ttagaatttc cacaatatat tgaatggagt gaaagataaa
    41101 tgggagaaaa aagaagtaaa accggaatta tttctgtcga aaaacctact tggtttcctt
    41161 tggaagatga gacagggaat ttcccggtat atggtactgc gttgccaatg ggaacagcag
    41221 taagtatcaa accaacagct aattatgaaa caacacaaga ttatggggat tcagtggttc
    41281 aagatcaatt tacagctttt ggtggtgcag aagttgaact ggaagcaaat ggatatactc
    41341 ataaagtttt atctacaatt actggaggga aaattgttaa aggtggtgcc ttgcgttctg
    41401 gagaagatat tgcgcaagat ggtgcgtttg catatagacg taaaaaatcg aatgggaaat
    41461 accgttatac ggtcttttat aaaggacagt ttgctctaga ttcagatgaa acgtcaacga
    41521 ttgaaggaag taaagtaagt tttactcatc caacttggaa gggttcattt gtagatgtac
    41581 caggacttgg atatatgtat tcagttgatg aagatgatga aggcgtggat aaagcaatga
    41641 tcggaaattg gtttacaaaa gtagcaattc caattgaaga agcagaactt tcaggaggta
    41701 cagaataatg tcaaaatatc aaacaacgat taaattaacg aaaaaagatg aagaaggtaa
    41761 atatgagcaa gtacaattta aatctgctga atttttacca ggaacagttg tagaagatgc
    41821 tgcaggagtt atggaagaaa tgcaaacagc gactgataaa caatcagtta aaaaagcttt
    41881 aagtcgtgct tattcattta ttgcagatac tttatttgag ggacaattta ctggtgaaga
    41941 ttattgcaaa ggaattgatg ctcgtgagat tgcctcattg acaggaaaat tattgaagtc
    42001 tgttactgca ggttttgatg aaacttatac agagacgaaa aaaaagtaag tgaggcgctc
    42061 aagtcacctt catttaagta ttcgattact taccgagaat tagatataaa gacgcaatta
    42121 ctcgaagcag gttggacgtt accagaaatt gaacgtactg acttggatga gttaatgcgt
    42181 ctttttgctt ttagagatgc ggtaaaagag catgaagatg ttgagtacta tgataatttc
    42241 actcaatttt aggaggtgat actttgaata acgatgacct aattctgaag atgatactag
    42301 atgaatctgg ttttactgcc ggtatgaata atgctgtcaa aaagttgaac tcttttgatg
    42361 aaacaatcga aagaaaaagt agaaatggtg gcagttcatt aggtagtatt tggaaaatat
    42421 ttgctggaag ttttctagct agcggagtaa ctagaatcgt aggagctggc tttgatctaa
    42481 tcaagggttc cataagtgga gcggttgatc gagtagatac gatgaataac gctctacgaa
    42541 atttccaaaa tatgggattt agtaattcag aaattatgaa gaatatcgga aagaatgggc
    42601 ttttatctca aggtattcaa ggacttccta ctgctttgaa tgatgcgata agtcatgttc
    42661 aacttcttgc ttcttctaca ggtgatttaa ctcgttcaac tcaaatattt aaagctttaa
    42721 atgatggaat tcttggtttc ggtggttcaa ctgatcaagt taatgaagct gttattcaat
    42781 tatctcaaag tttctcaaac ggaaaagtag acgcacaaac ttggaactca atgatcaacg
    42841 ctcaacttgg acctactctt tctgctattg ctaaaaagat gggaattaca atgggagatc
    42901 tgaaagaagg tttatctcaa ggtaagattt ctgttgaaga attccaaaat caattaatag
    42961 aaatggatac caaaggtggc ggaggactta aatcattaag tcaaatcgct aaagattcta
    43021 ctaagggaat taaaacctct atacaaaatg caaaaacagc tgttacacgt ggtgttggtg
    43081 aggtaataga aggattaaat aaagcattag tagattcaga tttaggtgga tttaagggga
    43141 ttattgataa agttgccagt tccatggaat cttttttgaa agtaattgct gcaaatattc
    43201 ctagagcagt gtctttttta agtaatcttt ttgatgcagt tcaaaaattt ggctctgcat
    43261 tgaaattcat gatgccattt ctggttcctg caactactgc ttttggcgca ttaatgtttc
    43321 aacttaaagg aataccaaca attataaaaa gcttcaataa ttttaagaat gccataatcg
    43381 gtgttggaaa ttcactaaag attatggggg ctatagccgc cgcaaatccg tttgttttga
    43441 ttgttggagc cgttgttgga gcgattgctg tatttggcta ttttatggca accaacgaag
    43501 aggttagaaa caaagttata tccgtttgga atgatgtaaa agattccgta cttggtgtat
    43561 taaagaatat aaaagattgg ggaattgata cttggaattc tgctaaagaa atggcatcaa
    43621 atgctgttga gagtgtcaag gatgcttggt ctggaataaa ggaatggttt tcaaatactt
    43681 ggcaaggcat taaaaatgga gcaacaggtt tatttgataa aacagtagaa acatctatga
    43741 atgcggttga tagtgtaaaa aacgcatggt caaatacaaa gcaatggttt tctgatattt
    43801 ggcagagcat aaaagattca gcaactgaaa aatggaatga aattaaaggt tctatcatgg
    43861 aagttgctgg tccattgatt acaggtttaa agaacgcatt cttgcatgtc actttttatt
    43921 tagagacctt atggaataat ctagttgaga ttggtaaaaa tgtttttgag attttaaaaa
    43981 atgttatact tacgccagtt ttgtttatta cctccatgat ttctggtgga tgggaagaaa
    44041 caaaaaacaa catgattggt gtatggaata atattaaaga aagtgctcta aatatttggg
    44101 agtctataaa aaatattttt gttagttaca ttacaaatat ttattttgct gcgcttaata
    44161 tttggacagg gttcaaactt actttgataa acatttggaa tgaagtagta agtcaagcta
    44221 aatcaatttg gattaatgta aaatactttt ttattaatct ttggattgac attaagtatt
    44281 ttgctattca aaaatggatt gaattaaaat tcgggattat tcaaacttgg attgatttaa
    44341 aatataatgc tattactact tggaacaata ttaaacagtt cttcaaagat acttggcaga
    44401 acattaaaga tatagcatac aatacatgga tttctataaa gaattccatg atcaatactt
    44461 ggaataacat caaggaatct ttctggaata ttgttactgg aattgttaac tccgctgaaa
    44521 atgcatggac taatctaaaa aatggtgttt caaaagcaat taatcgggtg aaagaaatct
    44581 ttgattcatt aagggaaatc aatttattcg aaatcggtaa gaatatcatt gatggactta
    44641 tcaatggtgt agtagaaaaa tggaatgcat tgaaaaagac tattaaagga atagctggaa
    44701 gtatcaaaga ttctattaag ggtgcattag gtattcattc tccatctaga tggatgaggg
    44761 atatggtagg taaaaatatt gttcaaggta ttatcgttgg tattgataaa gaaaaaagta
    44821 aattggatca gacaatgact gatttagtga aaactccgtc ggttcaacca gttattacag
    44881 ggtctaatag tcaaccagtg gtacaagcta aacaaaatac atcttcaaat gcagtgaatg
    44941 aaattcactt gcatttaaat gtttatggag atctacctga ttcgatgatt aaacaaatcg
    45001 ccaagaagat gaaaacagaa ttgacgagac aaatgaaacg agatgctgat gcagtaggag
    45061 ggacattata tgcaacttaa aagaggacaa ttttttatca atcaacatta ttcttctgag
    45121 tttaacgtat atattcaaaa taggcctgcc tctgtttcag ctagtcgtgt aattgaattg
    45181 agagaacgtg aaggcaatga ctcaattatt atcgataaag cctattacaa aaacgttact
    45241 agaaaaattg aatgttatta caaagcacca tcgattgatt tagtgcagga atgggaagat
    45301 cgaattactg aatggttaga tatgaactct tacagtgatt ttattcttta ttacgatcaa
    45361 caatatatct atcaagctat agtaaccgaa gcgccagaat ttaaaggaac aagaaaaaca
    45421 gggaacatag ttccatttga atttacagtt agtcttcgac cattcaaaga aaattatagt
    45481 ggtcgttttg ctattcaaca gataaaagct ttcgagttat ttaatccaga gaagtatgct
    45541 tcaaaaccgc ttattaaatt gagtggttct ggagatgctt ctttttatat taataatgat
    45601 aaatatgatt tgaaactatt agatagagaa ttatatatag attctaaact agaagagtct
    45661 tatcgaaagc tagatgacaa tttagaacat caagatcatg tcactttatt tttagatttt
    45721 ccatttctat accctggaaa aaatgaaatc aaatggacga ataacataca ttcgtttgag
    45781 ataataccaa ggtggtggag aaaagtatga taccaagaat atatagtcct accgagacag
    45841 atttttctac gaatggttta gggattttga aggacaccac aaaatgtgag atatatgaag
    45901 tagcaaatgg aaaatatgaa ttagagttgg agtatccatt aggtactcga tttgatgaat
    45961 attttgaaaa tgactatcaa ataaaagcaa agtcaaatga tcaagaagag tatcatatct
    46021 tttttattga tgataaagat attgatacct ttttagatac cgtaactatt tatgcccaga
    46081 gtcgtacaaa tcggcttgga agacgagcgg tcacttttgc tggagtcgac tctaaaactg
    46141 gtcgagaagc aatggcaatt attgaaaaca atatggataa aaaatcagat atacgcttat
    46201 attctgatat tacaactgta tcaagtacaa cttttgaagc aagaaatgtt ttaaattgta
    46261 ttgctggtga acaaggatct ttacttcagt attggggcgg agaaattaaa cgtgagcctt
    46321 ttaagctatc tttattaaag cgaagaggtc gtgataatat tggcacaatc cgatatggaa
    46381 aagatttatc tgggttaaaa gttaagttag attggacagg cgtgaaaaca agaattattc
    46441 cgtatgctga tcctcaaagt gatgcaggta caactagccg aatttatggc tcgccagtag
    46501 atagcgaata tattaataat tatcctgatg tatatacaga acacgttcaa ttcacagaag
    46561 aacagggagt taaagacgtt aatagcttaa ataaaatagc taagaattat ttcaaaacaa
    46621 ttaatccagg ctgtgataaa ccgaagattt ctattaccgt tgagttcgat aaattaacgg
    46681 acaccgaaga aggaaaagaa ttcgctaaga taagaaatta tgggttattt gatacgttta
    46741 aaatatatca tcgaaaatat aaactatatt ttgaatcgaa agttagcggt gttcaatatg
    46801 attcattatc tgaaaaggtt ttgaaattgg aagctgggga tgctcaagtt gctttttatc
    46861 aacaacaagc tgttactatt caagataaat taaaagatta tgctacgaat aattatatga
    46921 gtagttttaa tgattatgtg tcctctatga ttgcaggtca aggaaatgca ggcggttatg
    46981 tagttttatg gccaaaagaa aaaccttcaa atatttttat aatggatagc cctgatttaa
    47041 acaaggcaaa agaagtatta agaatgaaca aaaatggaat tgccttttct aaaaatggtt
    47101 ggaatggtcc ttttaattcc gcttggacat tggatagtat attcaatgct aattttattc
    47161 aaacaggatt aataaaggca gatatctttc aaaactcttt taataaaact ggagatgtat
    47221 tgaaattagt taatggacta cttcaaattt ggaataacaa aaagaaaata atggagttaa
    47281 ccaaaaaagg aatggagttt tggaattcta atagttcaat tggaacgatt ggaacaactg
    47341 attctgctgg taatcctttt cctggagctt ctactcccac acctattgaa gataattctt
    47401 tagttattcg tacaaatgga gacggcaaat atattttgat ttctcctaaa gttggtaaag
    47461 gattagtttt attaggaaat ggtaaagcaa tttattttgg agacttagat gtacaaggca
    47521 aactcacagt taacggaaaa gaaatcacag ggaacaacag tggaggaagt gatcctggaa
    47581 ctatccctcc tcaattgacg acggaagctg aaaaaagagc atggaaaatt tggacaatgc
    47641 tgaaagctcg tggctattct gaatatgcag ctgcaggtat tctaggaaat attcaggggg
    47701 aggttggagc aagtatgaac cctgatacag aacaacttgg tggtccagct tatgggattg
    47761 ttcaatggga tggttctgct tatccgttag tcggatcacc aacttggaac ggacgagagt
    47821 atgttcagcg tttgatgaac accgcaggga ttcaagaaga ttatcgaagt attgaagccc
    47881 aagtaaaatt attagattgg tgtatgttca acggtcaatg gctcggaaaa gtaaatccaa
    47941 ccacagtatc aggatttaaa tcgatcaatg atgccaaaag tgcagcgtat gcttttgaaa
    48001 tgaacttcga acgcccagct tctgcacatc cagaacgcca aaattatgcc caatcttggt
    48061 ataacaaatt acatggatta actagtccag aacctggagg gaatttcatt tgtccaattc
    48121 aaaaaccagt gacagttact tcagaatgtg gatggagaac tagtccaata aatggcggcc
    48181 aagaatttca taatggaatt gatcttgtaa atggaaatcc taatacacct gtttttgcag
    48241 cattagatgg ggaagttgtt caggctggtg ctaattatta tgactggtat ggtaattacg
    48301 tggttattaa acataataat gggaagtgga caggttatgc tcatttgtct cgtattgatg
    48361 tttctgttgg acaaaaagtc cagaaaggtg ctcaaatagg cttgatggga acaactggtc
    48421 catctacagg agaacatcta cattttcaaa ttatgaaaaa ttattggcca cagccagttg
    48481 ttgattttga gaatccaaga aattatatcc aattttaagg tggtgattct atgagtaaat
    48541 ggaatgtcgt tttaagtaca acagaaccat ataattatgt ggggatgatt caagttcgac
    48601 aaggcaataa gaatacagag gttatggaag cgactatagt tgaaaatggt cttccctacg
    48661 atttatcaga atgtaaggta tattttgaat cagttgtagg tgggaaatat ccagtccaat
    48721 tagaaacaaa aattgtggat gctaaaaaag ggaaaattaa
//
LOCUS       DARPZJ010000016        46148 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.016, whole genome shotgun sequence.
ACCESSION   DARPZJ010000016 DARPZJ010000000
VERSION     DARPZJ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.016"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            46..2211
                     /gene="acm"
                     /locus_tag="SLE23_001155"
     CDS             46..2211
                     /gene="acm"
                     /locus_tag="SLE23_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HEI8468072.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2483..2968)
                     /locus_tag="SLE23_001156"
     CDS             complement(2483..2968)
                     /locus_tag="SLE23_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEI8468073.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3058..3403
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3448..4089
                     /locus_tag="SLE23_001157"
     CDS             3448..4089
                     /locus_tag="SLE23_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8468074.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4108..4743
                     /locus_tag="SLE23_001158"
     CDS             4108..4743
                     /locus_tag="SLE23_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8468075.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4761..5576
                     /locus_tag="SLE23_001159"
     CDS             4761..5576
                     /locus_tag="SLE23_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8468076.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5895..7331
                     /locus_tag="SLE23_001160"
     CDS             5895..7331
                     /locus_tag="SLE23_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8468077.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7520..9967
                     /locus_tag="SLE23_001161"
     CDS             7520..9967
                     /locus_tag="SLE23_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEI8468078.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10197..11264
                     /gene="rlmN"
                     /locus_tag="SLE23_001162"
     CDS             10197..11264
                     /gene="rlmN"
                     /locus_tag="SLE23_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEI8468079.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11457..12560)
                     /locus_tag="SLE23_001163"
     CDS             complement(11457..12560)
                     /locus_tag="SLE23_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8468080.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13113..13661
                     /gene="aac(6')"
                     /locus_tag="SLE23_001164"
     CDS             13113..13661
                     /gene="aac(6')"
                     /locus_tag="SLE23_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEI8468081.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14206..15867
                     /locus_tag="SLE23_001165"
     CDS             14206..15867
                     /locus_tag="SLE23_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8468082.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(15937..16284)
                     /locus_tag="SLE23_001166"
     CDS             complement(15937..16284)
                     /locus_tag="SLE23_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HEI8468083.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16368..17309
                     /locus_tag="SLE23_001167"
     CDS             16368..17309
                     /locus_tag="SLE23_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468084.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKTQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17310..18353
                     /locus_tag="SLE23_001168"
     CDS             17310..18353
                     /locus_tag="SLE23_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468085.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18359..19429
                     /locus_tag="SLE23_001169"
     CDS             18359..19429
                     /locus_tag="SLE23_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468086.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19419..20372
                     /locus_tag="SLE23_001170"
     CDS             19419..20372
                     /locus_tag="SLE23_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8468087.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20384..21394
                     /locus_tag="SLE23_001171"
     CDS             20384..21394
                     /locus_tag="SLE23_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8468088.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21679..22500)
                     /locus_tag="SLE23_001172"
     CDS             complement(21679..22500)
                     /locus_tag="SLE23_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEI8468089.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22597..22875)
                     /locus_tag="SLE23_001173"
     CDS             complement(22597..22875)
                     /locus_tag="SLE23_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468090.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23143..25152
                     /gene="metG"
                     /locus_tag="SLE23_001174"
     CDS             23143..25152
                     /gene="metG"
                     /locus_tag="SLE23_001174"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEI8468091.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25631..26218)
                     /locus_tag="SLE23_001175"
     CDS             complement(25631..26218)
                     /locus_tag="SLE23_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468092.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26393..27715
                     /locus_tag="SLE23_001176"
     CDS             26393..27715
                     /locus_tag="SLE23_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8468093.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            27870..28646
                     /locus_tag="SLE23_001177"
     CDS             27870..28646
                     /locus_tag="SLE23_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEI8468094.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28639..29208
                     /gene="rnmV"
                     /locus_tag="SLE23_001178"
     CDS             28639..29208
                     /gene="rnmV"
                     /locus_tag="SLE23_001178"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEI8468095.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29201..30085
                     /gene="rsmA"
                     /locus_tag="SLE23_001179"
     CDS             29201..30085
                     /gene="rsmA"
                     /locus_tag="SLE23_001179"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEI8468096.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30536..31165
                     /locus_tag="SLE23_001180"
     CDS             30536..31165
                     /locus_tag="SLE23_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468097.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="SLE23_001181"
     CDS             complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="SLE23_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEI8468098.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32607..33029
                     /gene="mgsA"
                     /locus_tag="SLE23_001182"
     CDS             32607..33029
                     /gene="mgsA"
                     /locus_tag="SLE23_001182"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HEI8468099.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33352..33888
                     /locus_tag="SLE23_001183"
     CDS             33352..33888
                     /locus_tag="SLE23_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEI8468100.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(33928..35691)
                     /locus_tag="SLE23_001184"
     CDS             complement(33928..35691)
                     /locus_tag="SLE23_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468101.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35694..37409)
                     /locus_tag="SLE23_001185"
     CDS             complement(35694..37409)
                     /locus_tag="SLE23_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468102.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(38188..38412)
                     /locus_tag="SLE23_001186"
     CDS             complement(38188..38412)
                     /locus_tag="SLE23_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468103.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            38603..41380
                     /locus_tag="SLE23_001187"
     CDS             38603..41380
                     /locus_tag="SLE23_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEI8468104.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            41461..41880
                     /locus_tag="SLE23_001188"
     CDS             41461..41880
                     /locus_tag="SLE23_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEI8468105.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            41892..42362
                     /locus_tag="SLE23_001189"
     CDS             41892..42362
                     /locus_tag="SLE23_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8468106.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            42379..43158
                     /locus_tag="SLE23_001190"
     CDS             42379..43158
                     /locus_tag="SLE23_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8468107.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            43145..43966
                     /locus_tag="SLE23_001191"
     CDS             43145..43966
                     /locus_tag="SLE23_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8468108.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            43983..45032
                     /locus_tag="SLE23_001192"
     CDS             43983..45032
                     /locus_tag="SLE23_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8468109.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            45045..46049
                     /locus_tag="SLE23_001193"
     CDS             45045..46049
                     /locus_tag="SLE23_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8468110.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT        15256 a         8049 c         9520 g        13323 t
ORIGIN      
        1 atatagtagg ttttattttt agttaaaata ggggagatag aaaaaatgaa aaagtgtaga
       61 aatattattt tatcaatgtt atttattatt actaatataa catcactgat tcctgttcat
      121 gtctatgcgg atgcaggcag agatatcagc agtaatgtca cttcgttgac cgtggaccca
      181 acgaatatta cagatggagg aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa
      241 aatatccaac caggtgatta tctttggatc aattggccaa gtgaaggaaa tattcgcggt
      301 gaaggattcc aaaaagaaat cccattaatg attgaaaata aaaatgttgg aactttaacg
      361 gtcagaaaag attctgcgca ggttgtgttt aatgaaaata ttaaaaacct agactcagta
      421 gaaggttggg ggcaatttga gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat
      481 acgggaccat tcaccgtgac gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca
      541 gcttctggtt cttcttctag cgttttttat tataaaacag gagacatgct acctgaagat
      601 actaagcaca ttcgatggtt tttgaatatt aacaataacg gcacttatgt tgaacaacca
      661 gttaaaatca gtgatgaaat ccaaagtgga caaagattag atccaagtac gtttgaaatt
      721 aatcaaatac acttaggtga acagaaggtt tatagaggag aagagggaat ccaacaattt
      781 ttacaagatt tccccagcgc tacatttaat ttttcagtaa ctgataatta cattgaaata
      841 actataccaa aaaactttgt caatcttagg aaaataatgg tgagttataa gacgatcata
      901 gaaaacccag aacaaataaa ttttgagaat cattcggaag cttggtttaa agaatttaat
      961 aaacctgctg ttgatggaga aagtttcaat catacagtta aaaatatttc agcttctggt
     1021 ggagtcaacg gtacagttag aggcgaattg aagattttca aatatatcaa tgacacagag
     1081 attggtatcc caaatgtgac tttcgaatta agacgagcag atgaacagcc tattcaagga
     1141 cagtctagta tcctgttgac ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa
     1201 gtaggagact atgttgtaaa agaaaaagaa gcacccaatt ggattgattt tgatccacta
     1261 agttcaaatg aactcaaatt ctccataaac gaaaatgata cagagggagt cagtttacct
     1321 atttataaca agaaaaaggt tacgaacatc acagcaacta aaatttggaa cggtggaacc
     1381 actccaagac cgagtattta ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca
     1441 gttcctgatg cagaaacaaa acgattagac aatggaataa cttcagtgac ttgggaagat
     1501 atccaacagt atgatgatag tggaaacgaa tatacgttta aagtgcaaga agtagatcaa
     1561 aacggaaatg attatgtccc ttcaggttat caaaaaattg aaaacgggct agtcgttaca
     1621 aatgagaata aagaagtcat ttcagtctca ggacaaaaaa catgggaaga caatgagaac
     1681 caagacggca aacgaccgac gacgatcaca gtaaatctat tagccgacgg tcaaccgatc
     1741 caacacaaag aagtaagtga aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa
     1801 tacagagacg ggcaagaaat catctatact gtaacggaag acaacgtgcc cgaatacagt
     1861 acgacgattg acgggtataa catcaaaaac agttatacac cggaaaaaac aaatatatct
     1921 ataccaggta gccatataac accgtggaaa aattttccag agaagacaga gagagagaaa
     1981 attagaaatc tattctctca aaaattgcaa atatttgctc atacaggaga atccagcgaa
     2041 caaagaagca attatattag taagagagct gtacctaaac agataacaaa taaatcaaaa
     2101 agcattcttc ctaaaacaag tagtaaaaaa tctagttttg ctgtaatcat tggtttattg
     2161 atagtaacta tctgtgctgg gatattctta caaaaatata aaaaagttta gttagaatat
     2221 aatatttttt gttaaatatg actgaaatca aaagaataaa attccgattt ataatcgaaa
     2281 aaagaagcat ttttatatat gcttcttttt tcgtagaatc aataaatatg gatttggcta
     2341 actatggaag aatactcgta ttagttttca gcgttcatac tagttgttac attgtttgat
     2401 tggccaaaag aatttctgat atattttgtg ctaaataaag aaaaagacgc ttgaattggg
     2461 aaataagaaa actactctat cattacaaat tttcataaac tggcagatgt tctaagtaaa
     2521 caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt agtggtattg atatttggat
     2581 gaaagcctac ggtatcttga cgatcaatag cagcatcgat cacgacttgg atttttttct
     2641 ctttgtcgtg catcaatgct aatggagtca ctgtacctgc tggaacgcct aggaggtcag
     2701 gaagctgttc ttcagaaaca aaagataagc gcttttcttt taattgttca gctagttgtt
     2761 ttaaatcggc gtgcttttca tcaggcaaga tgacaagata gatttgtttt ccttttcttg
     2821 atttcaataa tagatttttt acttgcggac caggtaggga aaaagggaca tttttgactg
     2881 acgtaatcgc aggatgatcg actttttgaa aagagatacc cagttttttt agtagttcat
     2941 aagcttcttg ttcggttgca cgactcatcg cgcatcaccc tccttttttt attagtgtat
     3001 cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat tacacgtaaa gttaaaacaa
     3061 atgacatcga aaagaagagt agccgttagg tgtttttaga gagtctctgg ttggtggaaa
     3121 gaggcagcag ttaaccgtga aacacatctt ggagtcgatt ttctgaagcg tatagtagga
     3181 aaatccgggg agcccgttac agctgcggtc gttgctagat gaccagataa ggctggcttt
     3241 tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt aacgtccttt gatcttcgga
     3301 tcaaaggact ttttgttttc atctgaacgg caacgactgt gtgaggtttt ttctgcaagg
     3361 aaaaaataaa cagaggtgga accacgtata atacgtcctc ttggcatttg ccaagaggat
     3421 ttttttattt taaaggagga aaagaagatg gagtatttga ttgaagttat gccgcaatta
     3481 ttagtaggag cactcacaac attgaaatta tttttattta ccttgattgg ctcattacca
     3541 ttagggattg ttttagcatt aggattgtct ttgcatttta agccgctacg ctacttgctt
     3601 caaacatatg tatgggttat gcggggaaca ccgctgttgt tgcaactgat ttttattttt
     3661 tatgggttgc cgacgattgg gatcgttttt gatcgtttcg aagcagcact cattgccttt
     3721 atcttaaact atgcagctta ttttgcagag atctttcgtg gagggataca atcgattcct
     3781 caaggtcaat atgaagcagc gcaagttttg caattaagtc cctttcaaac ggtgacgaaa
     3841 atcgtcatcc cacaagtgac aaagattgtt ttaccttctg tagggaatga agttatcaac
     3901 ttggtcaaag attcttcctt gatctatata ttaggtttag gtgacgtaat gcgtgctggg
     3961 aaaatcgcga tggaacgcga cgcgacttta ctgcctttgc taggcgtggc aatcatctat
     4021 cttacattga ctggtattct aacaatcgta atgaaacaag ttgaaggaaa attaaattat
     4081 taccgctaac tgataggagg aagaaatatg attgaattga agaaagtgaa caaagcattt
     4141 ggtgaaaaaa aaataatcaa agatttgaat ctaatcattc cagatgggaa aacattagct
     4201 atcgtaggtc cttccggtgg cggtaaaacc acgcttttac gtatcttggc tggcttagaa
     4261 agttctgaca gcggagaatt ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa
     4321 atgaaagaac aagttgtagg agtcgtattc caagacttcc agctatttcc acatctgaat
     4381 atttttgaaa acattacctt agcaccaaaa atggtattga aacagacaaa agaagaatac
     4441 accaaaaaag cagaagaatt agcggcttca ttagggatta gtgatttatt gaatatctat
     4501 ccttatcagc tttctggcgg acaaaaacag cgggtagcga ttgccagagc attggctatg
     4561 aatccacggg tattggctta tgatgaacca acaagtgctt tagatcctga attacgccag
     4621 caagtcgagc gtttgatcct atcattgaaa gaagatgggg taacccaaat tattgtcacc
     4681 catgatttag tatttgcaga aaatgtcggt gatcaattac taaaagtttc cccaattcat
     4741 taagaaagga gaagatagag atgaaaaaaa ccagttttct attcgctttg atcgcaggtc
     4801 ttcttctttt tgcaggctgt tcgaacaaaa aaacttcagc agataattgg gcgactatca
     4861 acgaagagaa aaaaatcgtt ataggtttag acgatacatt tgttcctatg ggatttagag
     4921 ataaagacgg gaagctcaca ggatttgata ttgatttagc caaagcagtc tttgaacaat
     4981 atgggattac ggtagacttt cagcccattg actggtcaat gaaggaattt gaactgaaca
     5041 atggaacgat cgatttgata tggaacggct attccaaaac gccggcaaga gaaaagaaag
     5101 tgcaatttac aaaaccttat atggaaaacg atcaagtgct gatcacacct aaagaatcag
     5161 gaatcacaaa ctttggacaa atgaataata agagattagg tgcgcaaaat gggtcatctg
     5221 gttatgatgt atttacgaaa caaccagaag tattaaaaga gatagtcaaa aaccaagatg
     5281 ctgttttgta tgatagtttt aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg
     5341 gtctgctgat ggataaagta tacgcagact attatttgaa acaaagaaac gaactagaag
     5401 acttcaacat aacaaaaggt tcttatgaga gtgaggattt tgcagttggt gcacgcaagt
     5461 cagatagtac attagtgaaa aaaatcaatg aagccctaga tcaactagag aaaacaggtg
     5521 aattccaaaa aatatccgat aaatggtttg gcgaagatgt tacgccgaga aattaacaaa
     5581 taggggactg tgacaaaaga cgtgtcacag tccctttttc cgaataaaca gtgttctcct
     5641 gccaactcct tgtgactcgg agctgaatgg caggctcaca acctcttggt aaacggtgtt
     5701 caaaagccag tttttcggta ttaagccaaa tttatgcaaa aatgtagaaa gccattttca
     5761 caaaattttt cttactactc gaaactaagc gactttttca caacctcctt tacatatttt
     5821 tattttgttg tggaaggggt ttcgtgttat tctaaaagag gaacgattga aggttatagg
     5881 aaaggaagag atgaatggaa cacaaagaac ttacctcatt tccaaaagat tttctgtggg
     5941 gctctgcttc tgcagcgtat caagtagaag gagcttggca agaagatggg aaaggagaat
     6001 cagtctggga tcgatttgta cggatacctg gaaagacatt taaaggaacg aacggtgatt
     6061 tggcagtaga ccactatcat cgttataaag aagatattgc tttaatgaaa gaacaaggtc
     6121 tgaaagctta ccgcttctct gtagcttgga cacggatttt tcctaatgga cgaggagaag
     6181 tcaatcaagc tgggctcgct ttttatgaga gattgatcga cgaattgatt gaaaacgata
     6241 ttgaacctat gttgacttta tatcattggg atcttccaca agcattgcaa gatgaatata
     6301 atggttggga atcacgtcag atcattgaag atttcactca ttatgcagaa acattatttg
     6361 aggcattccg cgggaaagtc cattactgga ttagtttgaa tgaacaaaat atcttcactt
     6421 cattaggtta tttgttagca gcacatccgc caggtgtgac agacccgaaa cgaatgtatg
     6481 aagttaacca tattgctaat ttagcaaatg catctgtcat caataaattt cacgagttag
     6541 aaatgcctgg aaaaatcgga ccaagctttg cgtatacgcc aaattatcca attgacagta
     6601 atcctgaaaa tgttctggct gctgaaaatg cagaagacct gatggccaat tattggatgg
     6661 atgtctatat gtggggaaaa tatccgattg ctgccatgag gttcttagaa gaaaaaggat
     6721 gggcaccaac gattgaagct ggcgatgcag aattgctaga atctgctaaa ccagattttc
     6781 ttgggatcaa ttactatcaa acggcgacga atgcattcaa tccattaaac ggagttggtg
     6841 ctggaaaaat gaatacgaca ggaaaaaaag gttcatcaga agaaactgga gttcctggaa
     6901 tgtataaaaa agttgagaat ccatttgtcg aacgaacaaa ttgggactgg gagattgacc
     6961 cagaaggatt aaggatcgga ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga
     7021 ttacggaaaa tggcttagga gagtatgaca agttgacaga agataaacaa atccatgacg
     7081 actatcgaat caattactta caaagccacg tcaaagccat caaagaagca atttcggatg
     7141 gagcagaagt cctaggctat tgcacctggt cttatacaga tttgcttagc tggctgaacg
     7201 gttatcaaaa gcgatatgga tttgtatatg ttgatcaaga cgaaacacaa gaaggatctt
     7261 tggaacgata taagaaagac agttattact ggtaccaaaa actgattgaa gaaaatggag
     7321 agaaccttta gttcacatac ttaaaacaag aaggtacggc tggatatggc cgtgcctttt
     7381 cttgataaaa tcatttagaa attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa
     7441 gcgtcagttc tttcaaacaa aactttagtt cccttacttt tttttgtata atgaaacttg
     7501 atgaaatgag ggataataaa tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac
     7561 gaaaaaaacg aaaaagcaaa aacagcagca ggaacaaatg ctgacgattg gtgttgggtt
     7621 tgccttgatt ttatttgctg tcttcggctt tttaaaatta ggttttttag gaatattgat
     7681 tgcaaacggc tttcggatca ttgcaggaaa tacttaccaa atcctctgtc ttttattagc
     7741 cgtattagga ttttggattg tcattaagaa tacagagttt tcaattggta aaaaccgacg
     7801 ctggtttggc ggcatactct tttatttcgg tatcttatta ttgttacatg cccatttatt
     7861 tggcaaactc catactgggg aaccaaatat catggggacg acatgggatt tgttagccag
     7921 tgatataaaa caaagtcaag tagacaataa cgttggtggt gggatgattg gagcaatcct
     7981 ttatcatttt acttacttct tgattgcaca gcctggaagt tatttagcag cagtgctatt
     8041 actggcagga ggagcattcc tgttcagtaa tctggaaggc tatcagctgt taaatggtat
     8101 ccaatcaatt ggagaacgag tacaggaatt attggaaggt gatcctgcca agcaagctcg
     8161 aaagcaagcg gcaaaggaag agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg
     8221 cttagctgca aaagaagctg cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt
     8281 gagccagcaa agggaaaata ctgctgatga atggcaggaa ccagaaaata cagagccgga
     8341 gcagctaagt tttgttccaa tcgacagttt tcaagaaaat atccatcctg cgaatctaga
     8401 gaaaccagta ccagatacac caaaacagac caatacagca gaaggttttt cagatgagtt
     8461 gccagaggat gacggtacct cattagaatt tgagattgaa gcagaacagg aaaatcaaga
     8521 ctatgaatta ccgacagttg atttgcttga ttctatacca actgtggatc aaagtgatga
     8581 gtataaaaaa attgaaaaaa atatcggcgt attagaacaa actttccaaa gtttcggtgt
     8641 cgatgccaag gtcgtcaaag ccagcttagg accatccgtc acaaaattcg aagtccagcc
     8701 ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt
     8761 agcggcgaaa gatgtccgga tggaagcacc gattccaggt aaatcactga ttggtattga
     8821 agtaccaaat ggaaagatca gtatggtttc ctttagagaa atcatcgaag cacaaccaaa
     8881 ccacccagat aaattactag aagtaccttt aggacgtgat gtttctggac gggtacaaac
     8941 ggctgatctt tcgaagatgc ctcacttact cgtggctggt tcgactggta gtgggaagtc
     9001 agtagcaatt aatgggatta tcacaagtat attaatgcgt gctaagcccc atgaagtaaa
     9061 actgatgatg atcgatccga aaatggttga attgaatatg tacaacggca tacctcatct
     9121 gttgacgccg gtcgtgacga accctagaaa agcagcgcaa gccttacaaa aagtagtaca
     9181 agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga gtaagaaata tttctggtta
     9241 caatgaattt gttcaacaga aaaacttgga aaacggaacg aaacatccaa ccttaccatt
     9301 catcgtagtg atcgtagatg aattagctga tttgatgatg gtagccagca atgaagttga
     9361 agatgcgatt attcgtttag cgcaaatggc tcgggcagcg gggattcata tgatcctagc
     9421 tactcaacgt ccaagtgtgg atgttatcac aggaatcatc aaagcaaatg taccttccag
     9481 aatggcattt gcggtatcaa gcggtacaga ttctcggacg atcattgatt ctaatggggc
     9541 agaaaagctc ttagggcgag gagatatgct attcttgcca atgggtgaga ataaaccgat
     9601 ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa cgggtcgttc aatttgttac
     9661 agatcagcaa gaagctcatt atgaagagaa aatgatgccg acagatgaag ttgaaacgac
     9721 aggtgctcca gaacagccac aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga
     9781 aatgcaaacg gcaagtattt cccttctcca aagaagattt cggatcggtt acaaccgagc
     9841 agcacgttta gtagatgaac tggaagctca tggagttgtt ggcccgtcag aaggaagcaa
     9901 gcctcggaaa gtattcattg agcaggaaga aacatcagaa acgttgccgg acgataatga
     9961 catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa ccaataaaaa gacaaggcat
    10021 gatgatacca aaagaaaaaa tggttttttt ccatcttttc taatacggta tgatgtcttg
    10081 tctttttagt ttttgtgaga ttaaagttct attcgattta tttgtgaagt attgcattaa
    10141 ggaaatgaat catgtatagt atgtagcgaa actttgagaa aaagagggaa aatactttgg
    10201 aaaaacagtc catttatggc ttgacgaatg aagaattaat caattggttt atagaaaacg
    10261 gcgagaaaaa attccgagct gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta
    10321 atttcacaga aatgacgaat ctatcgaaac aattgatcga aaaattatcg gagcatttta
    10381 tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt
    10441 tgtttgaact ccctgataaa aacatgattg agactgtact gatgagacaa gaatatggct
    10501 tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg
    10561 ggctgctcaa aaagaaccgt gatctgactg ctggagaaat tgttgcacag atcatgatgg
    10621 tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg
    10681 ggatcggtga gccatttgat aattacgaca atgtaatgga ctttttgcat atcatcaatg
    10741 atgccaaagg attggcaatt ggtgctcggc acattacagt ttccactagt ggattagcac
    10801 acaaaatcaa ggaattcgct aataacggct tgcaagtcaa tctggctatt tccttgcacg
    10861 cgccgaataa tgaggtgcga acatcgatca tgcggatcaa ccgaagtttc ccaattgaga
    10921 aattgatgga agctgtggat gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat
    10981 atatcatgtt gaatcaagta aatgatagac cagagcatgc gcaacaatta gcagatctat
    11041 taaaagataa gaaaaaatta gcatatgtca acttgattcc atataatcca gtcagtgaac
    11101 atgatcaata ttctcgcagt ccaaaagctg atgtattgag attttatgat gtattgaaga
    11161 aaaacggcgt aaactgtgtg atacgtaaag aacatggtac agatattgat gcagcttgcg
    11221 gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt
    11281 ttttcaatta ccataaaagg agcagttttc ttaattaagg aactgttcaa cttaaataag
    11341 agaaaagatt ctatagcgaa agctataaag ctttttttga caagaaaaac cctcatcaag
    11401 caaagaaatg tcctcaattt gatgacagcc tgcttgatgg gggttttagc aattatttaa
    11461 ctgattttct tatatccttg ctggctttct tgtgtagcat gataagtttc tacgtcaaga
    11521 atggcctgtt taaatttttc tcgggtgatt tcataaggca catgtttaat atcatttgtt
    11581 gccatggctt tatctaagat tgcttctaaa tcggtcgtga cattgagatt catgtcggtt
    11641 aacgatactg gaagttggtt ctttttcata aacacataga ttttatcaaa caaatcgaac
    11701 tgctgatcca tcatcaataa ggtcagtaca ccataactga cagatgctcc gtgaaggtat
    11761 ccctccattt tttctagaac agtcgtaccg taatagaatg agtgtgccat agcagaatta
    11821 tagttattgt taactaaaac agaaaccaat ccggtagtaa caatgatatc cgaaacgact
    11881 tgttcaattg catatgaggg acgatcgtcg gcactatctt tcaatgcttg cgtaccataa
    11941 gtcaagagac gatcaatgca catttttccg atttggattc ctaatctatc cgtgtagcct
    12001 agatcatcgc cacgagcaga aaaagtagat tcgacttctt tggataaagc atcgccaata
    12061 cctgcccata agtatttatc aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt
    12121 acaggtggtt ttgaaggaaa gaagagtccg tccattacgc cttcttcgtt atagatgaca
    12181 cataccgcag tgacgggcga acagttcgaa ccaatagtgg gaaaggtgaa gactggttta
    12241 gctagttttt caccaatgac ttttacagta tcgcaagcac ggccaccacc gactgcaaac
    12301 aggacgtctg ctttttggac actttcatgc tggatcaact gttcaatatt tccataagtt
    12361 gaattacccc cgtaccagag actggcgaca acctctattt cctgtgtcaa agctactttt
    12421 attttgtttt ctgcctttga aagtgcagtc ttccctccaa tcagcactac ttttgtccca
    12481 tattctttga cgattccatt tgctttttca tacgcatctg ttccaatggt ataatttggt
    12541 aagaaaacac tttgactcat attcatttcc ttctttcttc gttgaaacgg gttaaaattt
    12601 taaagagtga tcgatctgac tgcggctgta gatggagtag aggtgaacct aagacaggat
    12661 aagtgatgaa taaggtggca tgaacacctt gaaatcatca ataagtatcc taaaaacgaa
    12721 caagtacaaa aacattgaaa acgacaataa tgaatttttg ttcctcttag tatttctacc
    12781 gattcccttt gcttttttgt aattatctaa aaattctaaa aattaagatt attatatgaa
    12841 aacaggtttt atttgtcaat tcataattgg ttttttttaa agcaaaagat aatctatatc
    12901 atgatgaaca aacagagttt tttcctccaa ttgatggctt tcctgatctt tcctattttg
    12961 aataaagtgt ttctgtataa tttttttatt ttataagtaa gataaataat gaaagaatag
    13021 agatactgat tggtagctaa agatttttga gcgagaacat ttcgtttttt caaaaggact
    13081 gttagaataa gcaagaacaa gggggaagac gtatgataat cagtgaattt gaccgtaata
    13141 atccagtatt gaaagatcag ctttctgatt tactgagact gacttggccg gaagaatatg
    13201 gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag
    13261 cggtagacca agatgagtta gtaggattta ttggtgcaat ccctcaatac ggtatcacag
    13321 gttgggaatt gcatccatta gttgtagaaa gctcccgacg aaagaaccaa ataggtactc
    13381 gattagtcaa ttacttagaa aaagaagtag cttccagagg aggaatcacg atttatttag
    13441 gtacggatga tttagaccat ggaacaacgt taagtcaaac ggacctgtat gagcatacat
    13501 ttgataaagt ggcttccatc cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat
    13561 taggttataa aatcgtaggt gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt
    13621 ggatggcaaa aacgattatt cctcgaccaa attctcaata ataaaaagag gttgtgacag
    13681 aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa ttacttcttg aatttttgtg
    13741 aaattccaac ttatttccga agaagctact tttggaacac cgtgtaccag aggttgtgaa
    13801 aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa aatggctttc tacatttttg
    13861 cataaatttg gcttaatacc gagaaactgg cttttgaaca ccgtttattc agataaggga
    13921 ctgtgacaag acttttgtca cagtttcttt ttgtttattc ttttttatct ttgtatggca
    13981 ataatagaca atataacgaa aattatttaa tggcttttgg aagaccatgg aaaaccttgt
    14041 acaaagctat tttttctgaa aaattccttg aaacctcacg aaaaaatcat tattttatga
    14101 aaaagacaaa aaaagtgttg attttttaat aattattcat taaactctta aacaacttca
    14161 gaaaatatta attattctga aaattccaat aaaggggtac gtaaaatgaa aaagaaattt
    14221 acatttggtt tggttgcggt atgcggcctt gtacttgctg gatgttatgg cggcagttca
    14281 gccacaagca gtagttcagc aaaaagcggt tcagcagatg gaggaggcgt atttaactta
    14341 gtcgtgcctc aagaaatgcc tacagctgac ttatcagttg caacagatac aatcagtttt
    14401 acagcattga ataacgttta tgaaggaatt taccgtcttg atgaagacag caaaccacag
    14461 ccggcaggag ctagcgagtt ggcagaagtc agtgaagacg gattaactta caaaatcaaa
    14521 ttacgagaag acgcaaaatg gtcaaatggt gatcctgtta cagcagcgga ttacgtttat
    14581 ggctggcaac gaacagtaga cccagctaca gcttctgaat atgcttacct gtatgcgcca
    14641 gttgaaaatg cagaagacat tacagctgga aagaaagata aatcagaact agggatcaaa
    14701 gcagttggtg actatgaatt agaaatcaaa ttgacgaaac aaacaccata tttccaatat
    14761 ctgcttgctt tcccatcatt tttcccacaa aaacaatccg tagtggaaga aaatggggat
    14821 gcctatgcat ctgcaagtga taaagctgtt tataatggac cattcacatt agaagatttt
    14881 gatggaccag gaacagatac agaatggact tataagaaaa atgatcatta ctgggacaaa
    14941 gatacagtaa aactttctga aatcaaagtc agtgtagtaa aagaatcttc tactgcattg
    15001 aacttattca aagatggcca agcagatgac gtgatcttgt ctggtgagtt agcacagcaa
    15061 aacgcaaacg atccagctta tacttctgtt aaagaagcgc ggacaagcta tatcgaattc
    15121 aatcaacgtg aaaagaattc accattcaac aatgtgaacc taagaaaagc tatttcttat
    15181 tctatcgatc gtgaagcttt agtaaaacaa gtactaggtg acggatcagt tgtctctaca
    15241 ggattgatcc catcagatat ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa
    15301 gctggaaaat tagtttctta tgacaaagat aaagcaaaag aatattggga aaaagcgaaa
    15361 aaagaattgg gcgttgattc tttagaattt gatttgatgg cttctgatga tgattcatcg
    15421 aaaaaagtaa tcgaatatgt tcaaaactca atccaagaaa acttggatgg cgtaacagtc
    15481 aaaccaacac ctgttccatt ctctgtacgt cttgaccgct caacttcggg tgattttgac
    15541 gcagtactag gcggatgggc tgctgactat gcagacccaa gcagctttac tgatttgttt
    15601 gtcacaggta attcatacaa ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt
    15661 aaagcagctt catcaacaga cgctggcgat gaacaagccc gttgggatga tttccaaaaa
    15721 gcaatcaaga tcatctctga tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt
    15781 cacctagtga atgaaaaaat caaaggtatc gttcaccatg cggcaggcgc ttcatgggat
    15841 tacaaatgga catacgttga agaataatcg ttaataccgt gagcatgaga aaaaacgagg
    15901 ctgcggcaaa tgtcgcaacc tcgttctcat attcacttat cctaacaaag aaaaaagcat
    15961 gaaaatagca gaaagagcaa ttagtattcc ggcaatgatc agccaaaagc tgtacatacc
    16021 gtagctggca gacgagagcg aggaaaattc tggttttttc tttcggttcc ttgttcgtgc
    16081 aagatggacc gatcgctgaa aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc
    16141 gccgataatc agaaacggca atgaccataa gaatagatca ttagataatt gaatgagtgt
    16201 aaaggaatgg ttgatgagat tttttattaa aataaccaga atcagtagaa aagctactgc
    16261 gtaggggata gatttttttt tcatttgatt gctcctttat ttttggttca ttatctaata
    16321 atgtagcgaa acatctgtca gaagtcaaaa gctaggggga aacattagtg aatagttata
    16381 tcaaatatgt attaaaacgt gtctttttca tgatcatcac gctttggtta attgcaacaa
    16441 tcaccttttt cttgatgcaa ttgctgccgg gcacgccata tacgaatcag gaacgtttga
    16501 gtcctgaaac aatcgagatg ctaaataaac aagtcggttt ggataaacca gttatcgtac
    16561 aatatgggat ttatctttct aatttgcttc aaggagattt tggaatttcc ttccaattta
    16621 aaacccagcc agtcgcacat ttgttagctg gaagaatcgg accatccttg cagttagggt
    16681 tacaggcaat tatctttgga acagtcctag ggacgatttt aggaacgatc tctgccatga
    16741 agcaaaatac atgggcagat acatcttcta cactcgtagc gatattaggt cgttccattc
    16801 caaactttgt atttgctgtt ttattacaat atatctttgc aatcaaatta caagttttgc
    16861 caatcgcaaa atgggatggc tttgtgtaca caatcttacc aacaattgcg ttggccatgt
    16921 cgccgcttgc tgactctgct cggtttatcc gtacggaaat ggtggaagta ctgcatagtg
    16981 attatgtgga attagcaaaa gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg
    17041 gtcttcgaaa tagtttgatt ccattgatga ctttattagg accgttagct gtagcattga
    17101 tgaccggatc actggtggta gaaaatatct ttgctattcc tggtatcggg gaacaattcg
    17161 ttaagtcaat cacaacaaat gattatccta cgatcatggc tgtaacgatc ctttactcat
    17221 ttatgctgat ttttgttatt ttgatcgtgg atctattgta cggtctagtt gatccaagaa
    17281 ttcgtgtttc agaagggagc cgaggataaa tggaaatgat accaaagcgt tatgaaacag
    17341 ttgcagatat ccctgcggat gaatttcttc cattacaaaa aaataccgaa gaagaacgtg
    17401 aacagattac tgcaccttct ttgaatttta tccaagattc atggcgccgt ttaaagaaaa
    17461 acaaagctgc cgttatttca atggttttac tattggtcat cattttgatc tctgtgatca
    17521 caatctttgt ttctcctcat gatccaactg cccaaaacgt ggcttatatc aatttgcctc
    17581 ctcgtattcc gggaatcaat atcgatggat tgaatggaaa agcaatggtt ggtggtgaac
    17641 ttgttgataa atatgctcaa gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag
    17701 acggtttggg acgtgatgta ttaagccgct tatttatggg aatgagaatc tcgttgctga
    17761 tcgcatttat tgctgcatta ctagatgtaa cgattggtgt agcttacggg ttggtttctg
    17821 gtttgttagg cggacgtgtc gataacgtga tgcaacgttt tttggaaatc ttatcaggaa
    17881 ttccaaacct cgttgtcatg attttgatgt tggtcgtttt tgaaccagga attttttcaa
    17941 tcgtggctgc tatggccatc acaaactgga taccaatggc acgtatcgtt cgtgcacaaa
    18001 caatgaaatt aaaagatcaa gaatatgttt tagctggatt gacattaggt gaatcaagaa
    18061 tgaaaattgc attcaaacat attttgccga atatctctag tgtcattatt attcaaatga
    18121 tgtttagtat tccatctgct attttcttcg aagccttttt aagctttatc ggtttaggtc
    18181 ttacgcctcc gtcagcttca ttaggaacga tgttgagcga agggtacaag acattcctgt
    18241 atctgcctta tctattatgg attccggcag taactttatc ggttatcatg attggcttta
    18301 acttacttgc tgatggattg cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat
    18361 gacgaaaatt ttagaagtga aagacttaga aatctctttt gatacgtatg ctggaaaggt
    18421 acgagcgatt cgcggtgtca attttcattt gaataaagga gaaacattgg cgatcgttgg
    18481 ggaatctgga agtggaaaat cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa
    18541 cgccaatata gatgctggtc aaatcctctt taaaggtaac gatatcgttg gaaaatcaga
    18601 aagagagatg caaaaaatcc gtggtaaaga aatagcgatg attttccaag atccaatgac
    18661 ctctttagat ccgacgatgc ccattgggaa gcaagtcgct gagtccctta gaaagcataa
    18721 taaagtttca aaaaaagagg gacaaaaagc tgcattagaa ttgcttaaat tagttggaat
    18781 acccgaagct gagaaacgta tcaacagtta tccgcatcag ttctcaggag gtcagcgtca
    18841 acggatcgtg atcgcgattg cactggtatg ttatccggaa atcctgattg ctgatgaacc
    18901 tacaacagcg cttgatgtga ctattcaagc acagattttg gagctgctga aagaaattca
    18961 gacaaaaatc gatacatcaa ttatctttat cactcatgac cttggtgtag tagcgaatgt
    19021 cgctgatcgt gtcgctgtca tgtatggagg aagaatcgtt gaagttggaa catcggaaga
    19081 aattttctac aacccgcaac atccctatac ttggggactg cttggttcaa tgccgacatt
    19141 agatagtgcg aacgatcgat tgtatgctat tcctggttct ccaccggatt tattgaaccc
    19201 gccaaaagga gacgcattct atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca
    19261 agaaccacca ttttttgaac tatcaaaaac acacaaggca gcaacttggc tacttgctcc
    19321 gcaggcaccc aaagtgacac cgccagaaga aatccaacgt cgctgggcta tctttaaaga
    19381 gaaacaaaaa catacttacg gtcaaggagg aattgctgat gccaaataaa ctacttgaag
    19441 ttaaaggatt gaaacagtat ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg
    19501 acatcagctt tcacatttat gaaggagaaa cattcggttt agttggagaa tctggaagcg
    19561 gaaaatccac tactggccgt acgatcattc gcttgaatga acctactgat ggtgagatat
    19621 tattcgacgg tcaagatata acgaagatca aagataaaaa aggtttgacg aaattccggc
    19681 atgatgttca gatgatcttt caagatccat acgcttcgtt gaatcctcgt atgaaagtca
    19741 gagatatcat tgccgaagga attgatgtta atggactagc taaatcatct gaagagcgtg
    19801 caaaaaaagt cgatgatcta ttgagaactg ttggattgaa tccaagccac ggtactcgtt
    19861 atcctcatga attttcaggt gggcaacgcc agcgtattgg tattgcacga gcattggcag
    19921 taaaaccgcg ttttatcatt tgtgatgaac caatttctgc actagatgtg tcgatccaag
    19981 cccaagtggt caatttgttg caagatctcc aaaaagaaca tcaattgacc tatctattta
    20041 ttgcacatga tttgtcgatg gttaaacata ttagtgaccg aatcggtgta atgcataacg
    20101 gcttgttatt agagatggga acaagtgatg aaatctataa tcacggtgtt catccttata
    20161 cagaaagttt gttatctgct attcctctac cagatccaga ccatgagaga aaacgcagaa
    20221 gaatcaaata tcaacctgaa ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac
    20281 cagaacattt tgtctatgca actgagcagg aagtcccata ttacgcaaaa aaactaaaac
    20341 gacaaaagga atctcttctg gttgctaact aggagggaca tagatgctaa aagcttttaa
    20401 attccgtatg tatccgacag aagaacaaaa acagcaattg attcgtactt ttggatgtgc
    20461 tcgatttacc tataaccatt tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt
    20521 agccaatttt tcgctcacac ccgctacatt aaaaaaagaa tacccattct taaaagaagt
    20581 agacagtctt gctttagcaa atgcacagct taatttggat cgggcttttc gcaattattt
    20641 caagggacgt gccagcttcc caaagcttaa aacgaaaaaa agtatgtggc aatcttatac
    20701 gaccaacaac caaacccgta cgatctatct ggaaaatggc tacttaaagt taccaaaaca
    20761 aaaagaacta atcaagataa atcagcatcg gccagttgaa ggatcgattc gctccgctac
    20821 gatttctgct cgatataatg aagaatttta tgtcgcacta ctttgtgatg tttcgccagt
    20881 aaaaaaagaa tctttagcta aatggatcgg gatcgcctat catccgaaga cattgatcca
    20941 aacatctcga cctctagaag taactttacc aaaatttcac cagacagaag aaaagctgca
    21001 acatgcacag cggaaattga atgtgaaagt ccgctccgct caccatagaa agatcaggtt
    21061 agatcaggca agcaattatc agaaacaaaa gagaaaagta atggatcttt atctgaaaca
    21121 aaagaaccag cgagaagatt atcttgaaca attatctggg aaattggtca aacaatatga
    21181 ctacttattt gtagaatctt ttccaaaaga agaggcacat gctgattttt ctattcacga
    21241 ctggcataaa ttaataacaa aattgcgtta taagtcccaa tggtataata aaaaatttct
    21301 tttgatcaat accgacggag cagaagaaag caattccgta agaaagagcc aagtagtaga
    21361 aaaaatgggc agacattcgg ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt
    21421 tagggttagc cttgttaata aaaagtctta atgacttttg tttctaggaa tttttctttt
    21481 gaagaaaagc tcactaatta tgacaaacca ataaaacaat agcagaaaaa gttcgtacga
    21541 gctttttctg ctattgttaa ttttttattc agaaagttta cgaatacatc aaaattctga
    21601 aacaaaaaac gtaactcaca aagagttgtt tttgcgtttt ttcttgaatg attaggtctg
    21661 aatcttttgc tcacaacctt attcatggtg ccccggcttg agctgataga tttttgaagg
    21721 acggccgatt cctacaggac gttcaccgat ctcatcgaaa tattggagca tagctttctt
    21781 aaaattggaa tgatcgatcg ttttataatc gatccctaag aatttagcaa atacttttcg
    21841 agcttccgta atcgtgaaat ctttacctaa aacttgtaga acttgcggct cgtgttccat
    21901 tttattgact acacggttga atgctttcaa gatgatttga ctatggtcaa aagccaaagt
    21961 atctttgcca gaagactctc cagtgactaa atcaagcgag atagccactt ctccgctaga
    22021 taaatggatc ttgttactat gacgttctag tgtgaaccag cgtacttcct tggcatcatc
    22081 tccggcgatt agcggttctt ctccaataaa ggctaagtag ctgactgtga cgacccagcc
    22141 tcgcggatct cgattaggcg tactgaatgt atgcagttgc tcaatatttt cttttgaaat
    22201 aaccacacca gtttcttcct ttgtttctct taagacgctt tctccagttg actcatcctt
    22261 ttggacaaag ccaccaggca atgcccatga atttcgataa ggatgccctt ttctttggat
    22321 caacaaaact ttcagctgat cttcttcttt gttatagcac atcagtacga tatcgacagt
    22381 caaagagggc ttgtcatatt ctggacgttc ctgtttttga taccagttaa gaaattcttc
    22441 ttcacttgct ttatgttcat aatataattt ttcttcttct ttagaagcaa aacggttcat
    22501 ctgaccacct ccattgacag taaaagtact ttttacctta ttgtagcaga ctctgaaaaa
    22561 aaaccaagga tttacttgaa aaatctaggt tatcatttaa atatgaaaaa taaatggaag
    22621 tatgagattg aataaaaaga aaagcagata aaacggcaat actttatacc gctcttcacg
    22681 aatggcaaag aagccacaaa taacgatata tacgtcaatg ataaaacgca aaatccaagc
    22741 tgctgtcata aaactgttca aatgcccatg gaggttaaaa taaccataca tacgaatata
    22801 aaaatagctg aatattaaat gtgctaatga aagaaaagca atactaagtg taaaaaaaag
    22861 atgtttcttc tgcatgattg ttccagtccc ttactaagat agatagtctt tattatacca
    22921 cgtgtgaggg gagaaataaa aagccgtttt ttagtagata tgaaacaaaa caaaaacccg
    22981 catttattca acctattcat ccttttaaag gatagattga acgtagatag aagtcgttta
    23041 tccagtcttt ttcattttga aaaaaagcta acagcatgct ttttttatgg tatactagca
    23101 aggaaacgaa ttcgcatcat gcgataaagg aggaagagcc ccgtggcaga aaaggaaact
    23161 ttttatatca ctacgccaat ctattatcca agcggcaaac ttcatatcgg caactcgtat
    23221 actacgattg catgtgacgc aattgctcgt tataaacggt tgatgggctt tgatgtgttt
    23281 tatctcactg gagtggatga acatggtcaa aaaatcgaaa caaaagcaga agaactaggt
    23341 gtaaaaccgc aagaatatgt agataaaatg gcggctgatg tcaagaaatt atggaaaacg
    23401 cttgatatca gttatgataa attcattcgc acgacagatg attaccataa agcagctgtt
    23461 caaaaaatat ttgatcgttt attagaacag ggagatattt acttaggtga atatgaaggc
    23521 tggtactctg tttctgacga agaattcttt acagaaacac aacttgcaga agtgtacaaa
    23581 gatgacgaag gtaacgtgat cggtggtaaa gcgccaagtg gacacgaagt agaattggta
    23641 aaagaagaat catacttctt ccgcatgagc aaatacgcag accgtctatt ggaatactat
    23701 gaagaacatc ccgaattcat ccagccagaa tctcgtaaaa acgaaatgat caacaacttt
    23761 atcaaaccag gattagagga tcttgcagtt tcacgaacaa cttttacttg gggagtacca
    23821 gtcaagagtg atccgaaaca tgtggtgtat gtatggatcg atgcattatc caattatatt
    23881 actgcactag gatatggctc cgaagatgaa agtctattcg aaaaatactg gcctgcagat
    23941 gttcagatgg tcggtaaaga aatcgttcgc tttcatacga tctattggcc aatcatgctg
    24001 atggcccttg atttgcctct acctaaaaaa gtatttgggc atggctggct attgatgaaa
    24061 gacggaaaaa tgtctaaatc aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt
    24121 tatggtttag atgcactccg ttattatttg cttcgtgctg ttccgtttgg gtcagatggt
    24181 gtctttacgc cagaagattt tgtttcccgt gtcaattatg atctggcaaa tgatctaggg
    24241 aacttattga atcgaacgat tgctatgatc aacaaatatt gtgatggact cgttcctgac
    24301 tatgcctcac ttgtcactcc atttgatagt gaactgtcta cgacggctgc taacgttgtc
    24361 ggacgttacc atgatgcaat ggaaaaaatg gaattcaata cagcattggc tgaaatctgg
    24421 gtgctgattt ctcgtgcaaa caaatacatt gatgaaacag aaccatgggt attagcaaaa
    24481 gacgaagaaa agaaagctga attgaatagt gtcatgatcc atttagctga atctttgcgt
    24541 atcgcagcga tattacttca gccaatcatg acagaaacgc cagagaagat cttcaatcaa
    24601 ctaggattgg actctgaaac aatgaatctt gaaggattac actttggcga atttccttca
    24661 ggaacaaaag tagttgcaaa aggtacacca atcttcccac gtttagatat ggaagaagaa
    24721 gttgctttta ttcaagaaaa aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa
    24781 tgggatccag aagaaacaga acttgtttca acgaaagaaa aacaaatcaa atttgatgta
    24841 tttgaaaaag tagaactaaa agtagcagaa gtcatcaact gtcaaaaagt agaaggggca
    24901 gataagttgc tgcaattccg actagatgct ggagacagcc aagaccgtca aatcttgtca
    24961 ggaatcgctg aattttatcc tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta
    25021 gcaaatctga aaccacgaaa gatgcgtgga caaatcagtc aaggaatgat cctttctgca
    25081 gaagcaccag atggctcttt acaagtaatc gaagcaccaa aatccatgcc aaatggctca
    25141 gaaatcgcat agaaattcaa agggggtatg acactagttg tgtcataccc cctttttccg
    25201 aaatttgaga agcaattttc gtaaattcct tcttattact tgaagccaat catataatac
    25261 agaaacagag aactatccaa aataaatcct agaaaaagaa gtacgagctt cgctgatttt
    25321 tgttaattta gaataatact aataggaatc gtaaaaacag aaaaaaagca taatgataaa
    25381 gggtcgggca gattttaatt gattcatctg gtactctttt ttattgtcct tacattcata
    25441 aagtttgaat gcaatgactt tattacatct atatttatat ctaacagtag cgttgatgtg
    25501 ttaattataa gttctatcac tttatgttca attagtttgt gctcttatat gtgtgattga
    25561 aaatatagat aaaaaaacaa tcatcggctt tgacttcgat gattgttttc tttattttgt
    25621 aaaaatccta tcacttgatt ttatggtaac cttttatttt tgtcttcaaa cggcttggta
    25681 agagagcagt aagcagtgca aatgggatcg aaaagacata ccagaaaatc gtacgtccga
    25741 taccataatg ttgatagagc tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca
    25801 aggagccagc tataaaccaa tgattatccc aatgcatgac ttcactaagt gccatcactc
    25861 caaaaggata gaaataaaaa tagatcccga ctaaggtcat ccgccagttc tttgtaaatg
    25921 ttccgatatt caataaaaag aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc
    25981 caaccaaaaa ggaatacaac atcccccaca agatcatcac aggacctttg atcaatgcaa
    26041 cgattgcgat gaacaaagtc agcaatatta gtttttgtga taacgttgca acagtcatta
    26101 atccaaataa aattaatgtg aaccaatgcc aatgggactg ctgttgttct ttacgggaaa
    26161 aatcgacccg gttggataaa taatctgcta atttcggata agaacgctta aaatccataa
    26221 actgttcctc cttcgtggaa aaggtaggtt tagtatacga aaaataaaaa agaaatacat
    26281 ccgtcttaag agggagtttt tcactgaaag tggagaaaaa agaatggtaa attaaaatat
    26341 tctcagttat actgaaaatt ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg
    26401 caaactaaaa cgagaaatca atctgtttgg cgcattagct accgttatgg gaaccgtgat
    26461 cggtgcaggc gtcttcttca aaactgctgc tgttactgct agtactcagt ctacaagttt
    26521 gacattgcta gcttggcttt tgggtggttt cttaacgatc tgtgctggat tgacagtggc
    26581 tgaattagct acagcaatcc cggaaactgg tggagctgta aaatatattg aagctgcgta
    26641 tggaaaattg cccagctttt tattaggatg ggcgcaaagc ttgatttact ttcctgctaa
    26701 tattgctgca ttatcgatta tctttgcgac acaattgacg aacttattac aattatctac
    26761 cgattatctt ttgttgattg cagtgatcac cgctgtttct gtgacagggt tgaatttgtt
    26821 agggacaaaa gtcggtgctt ctgtacaatc agtgacgttg attgttaaat taataccaat
    26881 tgctgtgatt gtcatatggg gattattgac cccaggacaa ggaactgtcc agttatttcc
    26941 aatcgaagct ggaaaagatg ttacttttgt cgaaggattg agcagtgcgt tgttagcaac
    27001 gttgtttgct tatgacggct ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc
    27061 ggaaaaagat ttgcctaaag caattattct tggtttgagt tttgtaacag tcgtttatct
    27121 attgatcaat tttgtttttt tgaaaacttt gccgattgat catcttgccg gtaatttgaa
    27181 tgcagcttct gaagcatcag acgtcatttt tggaggaatc ggtggaaagc tggtcactat
    27241 tgggatcttg atctcggtat acggtgcatt gaacggttat acactaactg ggatccgcgt
    27301 gccttatgcg atggctttag aagacgagct acctttcagt aaacagctga caaagctttc
    27361 aaagaagttt acggttcctt atgttcctgc ggttttccag ttagcagtag cttgtattat
    27421 gatgagcctt ggttctttcg actttttaac agacatgttg atttttgtga tgtggctatt
    27481 cagtttactg atttttatcg gtgtctttat tttaagaaaa aaagcgccgg aattgccacg
    27541 tccatataaa gtaccacttt atccaatcgt tccgattatt gcgattctcg gtgctatttt
    27601 cattttaggt atgacgatga tgacgcaaac gaaattagca ttgatcggta taggtgttac
    27661 cttgataggt atcccagtct attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat
    27721 ttcaacaaca gacagaaaaa gtacgaacta ggtcctctag atcttcgtgc tttttctatt
    27781 tcaataaaac aagttcttct attttgattt ttgctacttc tgcaagtagt gcttatgtgc
    27841 taaagtaaga atgaaaagga gagataaaca tgatatttga ttctcatacc catttaaatg
    27901 ctgaacagtt caatgaagat attccagaaa cgattcagcg agcacaagaa atgggggtaa
    27961 cgaaaatggc ggtcgtgggc ttcgatacgc caacgattga aaagtctttg caattaagcc
    28021 atgactatcc aaatatatac agtattatcg gctggcatcc gacagaggct ggcagttata
    28081 cgaaagaaat cgaaaataaa ttacaagaac aattgacttt accaaaggtt gtagcattag
    28141 gggaaattgg cttggattat cattggatgg aagacccgaa agaagtccaa gataaagtat
    28201 ttcgcagaca gattgctatc gcaaaagaaa tgaacctacc aatcagtatt catactagag
    28261 aagcacttga agacacgtat caaatcctaa aagaagaaga tgttcgagat atcggtggaa
    28321 tcatgcatag tttcagtggt gattatgaat gggcaaaacg atttcttgac ttagggatgc
    28381 atatttcatt tagcggtgtc gtcactttca aaaaagcatt agacgtccaa gaggctgcag
    28441 caaatgtacc aatcgaacga ttacttgtgg aaacagatgc cccttatctg gcaccagttc
    28501 cttttagagg aaagcgaaat gaaccaggct atactcgtta tacagtagaa aagattgctg
    28561 aacttcggaa tcttccgaca gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat
    28621 tatttggtct aagcgaacat ggataagatg aagatccaag agattatagt cgttgaagga
    28681 aaagacgata caagaaggct gcgggaagta gttgatgcag atacgataga aacaataggg
    28741 tctgcaatca atgaagagat cctgatgcaa attgaacatg cccaagagac tcgtggagtg
    28801 atcgttttta ccgatcctga tttttcagga gaaaaaataa gaaaaatcat tatggaagct
    28861 gttcctcagg caaaacatgc ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga
    28921 agccttggtg tcgagcatgc aagtgatgct gctattttag aagcattgaa aaaggtcgtg
    28981 acgccagaca tttcccaaac ggctgtttct gaaatcacta gacaagacct tttagactat
    29041 ggtttaatag ctggggcaca agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc
    29101 atcggttaca cgaacggcaa acaattggaa aaacgtttga agatgtttcg tattacgccg
    29161 aaagaactcg cccaagcaat gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat
    29221 tgcgacaccc tctagaacaa aagagatttt attgaaacat ggtttttcat ttaaaaaaag
    29281 tttaggacaa aattttctga ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca
    29341 aatagatgaa catacgaacg tgatcgaagt tggaccagga atcggtgcat tgacggaaca
    29401 attagccaag catgcaaaac aagtcgtagc atttgagatc gatgatcgtt tgatccctgt
    29461 attggctgat acgatgcaac cctatgacaa tgtgactatt gtacatcaag atattttaaa
    29521 gaccgatttg tcaacagctg ttagagaaac atttcatgag gagcttccgt taaaagtcgt
    29581 agcgaattta ccttactata ttacgacacc gatcatgatg cattttcttg aatcagattt
    29641 ggttgtggat gaactagtcg tcatgatgca aaaagaagta gctgatcgta tctctgctga
    29701 accaggaacg aaagcttatg gttcattatc gattgctgtt caatattata tggaagccag
    29761 tttagcattc atcgtaccaa aaacagtatt tgtccctcag ccaaatgtag attcagcgat
    29821 tttgaaactg acaagaagag atataccggc agtcgaagtg acagacgaaa aagcattttt
    29881 ccgattgaca aaagcggcat ttcagcaaag aagaaaaacg ctttggaata acttgcagca
    29941 ttcgtatggc aaagatgacc agacaaaagc atggttagca aaaagcttgg aaacagctgg
    30001 aatcgatcca aaacgtcgtg gggagacttt gtcattacaa gaattcgccg cattaagcaa
    30061 tgcgatgtca gaaaatatgc agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg
    30121 tcctgcatca agtaataaga acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt
    30181 tgggcttatt accgcagatg caagcttttg aacaccgttt aagaaagagg ttgtgggcct
    30241 gccgtttaac tctaagtcac aaggaacaat ttcaaaaaac agcttctcat gtttttgagt
    30301 tagttggtct tattacttga tgcaagcttt tgaccactat tatgccgaac aaggagatgt
    30361 gacacaaatt ttgtcacatc tcctattttt gtttcttgat caaaaaattc ttatacttga
    30421 tactcacact cattttgtat ggatttagaa aagaatatgt gtcttgacag ttattagtaa
    30481 gtgagttata ctaagtcgac atttatgtgt caagacatat taggagagag aaaaaatgag
    30541 aaaaaattca gttcgaaaac taacgatttc tgctttattg attgggatgg gggtcattat
    30601 cccaatggtc atgcctaaaa tcatgattcc accagcttcc tttactttgg cgtctcatgt
    30661 gccattattt attgcgatgt tttttacacc aggagttgca gtggctgttg cgctaggtac
    30721 gacatttggt ttctttttaa caacgccggt tatcatcgca ttgcgagcat tgtcacatct
    30781 tgtgtttgcg ttgattgggg cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa
    30841 tggacagttt acttttgcta attggcgttt ccaagggttc aattttgtga tcggtgtgat
    30901 tcattcttta gcagaaatgc tagtagtcag catcttttac tttattggta atatgcctga
    30961 aacatattat tctcaaggat atttttatac agtattcatc ttgatgggga ttggtgggct
    31021 tatccacagt ttagttgatt ataatattgc ttattttata gcaggaacac tcagcaaata
    31081 ttttgatatc cccgtattta cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg
    31141 gtacgcgaag aaaacgacat attagacatg atctctcaaa aaaaaaactc tcatctagta
    31201 atggataata aatcctctaa gatgagagtt ttttgtccta aaaagagctg caccaacatc
    31261 ttctggcaca gctctaacag ggggcaattt atggaagttt gatgacttgt tctgtttctt
    31321 tatcaaagaa gtggcctttg ctgatgttga aggcaaggtc gactatttcg cctggtttat
    31381 ggaaatctct tgcatctact tttgagatga actcagtaga accagttttt gtgtaaagca
    31441 tcgtttcagc tccaagtaat tcggaaacga caacttctga tttcactacg gcttcaggtg
    31501 aagcttcaag ggctacttgt tcactgtgga tgtcttctgg acgaataccg aagataactt
    31561 cttttccttc ataacctttt tcaactaata ctttgttttt tccttcagga atacgaagct
    31621 taagcccatg tccatctgtg ataacaccat ttttcaatgt cacattaaag aagttcatgg
    31681 caggagatcc aataaagccg gcaacgaaca tattgacggg tgtatcataa acttctttcg
    31741 gtgtaccgat ttgttggata aatccgtctt tcatgataac gattcggtca gccatagtca
    31801 ttgcttctgt ctgatcgtga gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt
    31861 tggcaatctc agcacgcatg gctacacgta atttagcatc taaatttgat aatggctcat
    31921 ccattaagaa gacttttgca tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt
    31981 gtccaccaga taaagcagct ggttttcgtt tcaagtattc tgtcagacct aagatctctg
    32041 ctgcattgtc cacacgtttt ttgatgtctg ctttatcata tttacgtaat ttcaagccaa
    32101 aagccatatt atcaaaaaca gtcatatgag gatacaatgc gtagttttgg aaaaccatgg
    32161 caatatcacg gtctttaggt gccacgtcat tcatgacttt tccgccgata tttagttctc
    32221 cttcagagat atcttccagt cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg
    32281 aaggaccaac aaaaacgata aattcacggt ctttgattga tagattaaaa tcagttacag
    32341 aataattttc tgcattgtca tattttttat atacgttttt cagagccatt tctaccataa
    32401 tacgttccac actttctttt ttagttttat taactattta aagtataaat gaaagcgtta
    32461 actaacttca atgtcatgtt gaacaagaat tttttctttt ttttgtcaat gtgctagttt
    32521 taagctttaa taaatatcca taagaaataa aaactgatac actggagtaa ataagtatgt
    32581 taacaatatc aaaaggagtg tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa
    32641 aacctatgat ggtgaaatta gcaacagcgt ataaaacaat attggaaaaa catgaacttt
    32701 ttgctaccgg gacgactggg cagaggatca cggaagcaac cggcttgccg atccatcggt
    32761 ttaaatccgg accgttaggc ggggatcagc aaattggagc catgatttcg gaggatcagt
    32821 tagatttggt gatttttctt cgagacccgc tggctgcaca gccccatgaa ccagatgtaa
    32881 cagcacttat ccgtttatct gatgtctatg agattccgtt agctacgaat atcggaacag
    32941 ctgaggtgct actaagagga ctggaagccg gcttcctaga ttttcgaaga atcgtccatg
    33001 aaatagacaa gcatccactt tcattttgat ggataagcgt atggaaaaat aacgtttaat
    33061 gttcgcctat atgtagctat aaaagctaaa caaactgata atatgcgata taatacgaac
    33121 gtattggata atataaacaa taatattagt ttttcgtatt tgcagtaaat gtgaaaatat
    33181 gctatagttt ctgtgggaaa agatcccaaa aataatacag agtagaaaat aaagcgttaa
    33241 gtgctaagag gatgggatgt tgcctcttgg acgaaggacg taatgttcgc ggttttattt
    33301 tcgcattcgc tgcatgatac gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa
    33361 caccggttag acgcacgtat gattgctatt atgggcttat tgattgcatt gatggtcact
    33421 ttgtcccgac tggtagcaat cgagacccca tttattaaaa tcagtgtcac atttattcca
    33481 caagtgatca tgggcattct ttttggtcct ttttggtcag ggataggcgc agttttagct
    33541 gatttagtag gaatggccct cttctcgaaa tctgcattct ttattggatt tacattgaat
    33601 gcatttattg aaggagcaat ctacggattc tttttctatc gaaaagagat cacttggaaa
    33661 aatgccattc tggctacgct tagtgtcacg ctgatcatca acttattttt gacaccatta
    33721 tggcttgcgt tgatgtacca tgtgccattg ttcagctggg tcgtttgggc gccccgcctg
    33781 ttaaaaacag taatatggtt accgattcaa tcaattgcca tttattacgt aggacgtagt
    33841 attccttaca aaaaaatttt aagaagttta gcgatccacg ctaaataaaa aacaagcagt
    33901 cttcccatcc cagaagactg cttgttttta ttgtgctgtg aattgtgctt gatagagccg
    33961 tcggtaataa ccatcttttt gaagcagctc atcatgggtg cccatttcga caatagctcc
    34021 ctgatccatc actaatatct ggtccgcatt tttgattgtg gacaggcgat gggcaatcac
    34081 aaaactggtt tttccttcca tcattgctaa gaaggcttgt tggatttttt tctctgtcaa
    34141 tgtatcgact gagctggtag cttcatctaa gatcaacata gggggattac tgatcatcgt
    34201 tcgagcaatc gtcaacagtt ggcgttgtcc atctgatatc tttaaccctt gaccgccaat
    34261 cttagtatct aatttttccg gcaaacgttc tacaaattca tacatataag aggcttttag
    34321 ggcatcattg atttctgcgt cacttgcttc cggattccca aaacgaagat tttctcgcaa
    34381 tgtactgtca aatagccaag tatcttgtaa caccattcca aaacttttac gtaatgtatc
    34441 acgttggata gagcggatgt catggtcatc gactgtaatt gttccttttg ttgtgtcata
    34501 aaaacgcatc agcaaattaa caagtgtgga ttttccggcc cctgtttttc ctactatagc
    34561 aatggtttga cctggataag cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc
    34621 ataagaaaaa gaaacatgat caaaagagac ttttcctttg atatttttgg gttccaaggc
    34681 ataggcatct ggcaaatcag gcttttcttc tggctgatcg atcaaatcaa atgctcgttc
    34741 tagaccagaa aaagcggttt gcagttgtgt cgtgattcca gaaagttcga taaatggttt
    34801 agaaaactga cttgagtaga tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc
    34861 actcttcaat gccaataggc cgccaactaa accaatcgat aaataagcaa ggtgatctac
    34921 aaaacgagaa gacgggtttg tcaaggaaga agaaaattgt gcccgttgtc ctttttcata
    34981 tagatcagca tttagcagtt caaattgctg ttgactagct tcttcttgct gaaaagcttt
    35041 cacgattttc tggttaccga ttcgttcggt cacaaagccc gagatatccc caataatcct
    35101 ttgctgtcta tcgaaatttg tttgtgaagc acgagcaacg atccaactca caaggaaaat
    35161 aattggtgta gaacaaagaa cgaccaatgt cagaagtgga cttagacgca tcataaaaat
    35221 aaacgaaaga atgatgattg ccactccaga aaataattga ttgaaggccg cagaaattgc
    35281 aatggaaata ttgtccatat catttgtaaa tcgactgacg atatttccgt gggagttttg
    35341 atcataataa cgaagtggca atcgattcag atgagcaaat gcatcttttc ttaattttgc
    35401 aacggataag taagctaacc gattgcttaa cacttggatg agccattgac tgactacgtt
    35461 gattaaaacg ataccaccga atagaataag taaatggaac agtcgattga agcggacctg
    35521 tccttctcca atcatttgat cgatactttg accaatttgt aacgtcatca caactgttgc
    35581 aatcccattg atgattccta gtatcacagc tagccaaatg tcttttgcat aggcagtaag
    35641 gtaaggaatg aatcggcgga gcgtctgcaa ggataatttt tttactttca taactattct
    35701 tcctcctgtg atgcgacgat ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg
    35761 gtaccctgag cagcaatctt accttgatcc atcactaaga tatgatgtgc ttcttgaata
    35821 gagcggacac gttgggagat aataatcact gtactgccaa gataagtctg tagcgcctta
    35881 cgcaaatcca agtctgtttg ataatccaac gcacttaaag agtcatctaa aatcagtaat
    35941 gctggcttgg caatcaaagc tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa
    36001 tttttcccat tttccatgac ttttgtatct aaaccatttg gaagctgacg gacaaattct
    36061 tctgcctgag cgattttcag agcttcccaa cattcttttt ctgtggcgtc tttcttaccc
    36121 cattgaaggt tttcacgaat agtcccggta aatagtacag aagtttgggg aacaagagca
    36181 atttgctgac ggagatgatc cagctgccaa gaacgaacat ccattccgtc cattataact
    36241 gtaccggaac tgacatcata gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt
    36301 ccggttggac caatgattcc aaggactgta tttcgcttca gctgaaatgt aatattttgg
    36361 agagaaagac cagaatcagg agtataacgg aagtcaacat ggtcaaaagc gataattgct
    36421 tcagaagaaa aatcgggagt agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct
    36481 agcacctctt tcacccgatt tcctgaagct tcggcacgtg tgaagatcac gacgaggttt
    36541 gaaacaacga tcagtgccaa aagcatttga ttcatataat tgatcaaagc aagaacttgt
    36601 ccttgttgca agctaccaat atttactttg atcccgccaa ctgtcagcaa acagatgatc
    36661 ccgacattca tgatcaaggt tgtagcaggt gataataggg cagagatatt ggaaacacgt
    36721 aaataattgt tcgctagatc atttgtgctt ttatcgaact tctctgtttc tttttttgtc
    36781 tgcgcaaatg cgcggatgac acgaacaccg ctaagattct gactaacgtg ttcattgagc
    36841 tgatctagtt tttcttgcac tttttggtag agaggaacgg tttttttgat gataaaaaat
    36901 aaaatgattg agaaaatagg caataatgct aagaaaaaca gacctacttc ccagtcgatc
    36961 acaaaagcca tgaccactga cccgatactt aaaaacggtg ctctgatcaa taaacgaatg
    37021 accattgcta aagctagctg aagctgattg atgtcgtttg tcattcgggt gatcaaggta
    37081 tctgttccaa aatgattcaa ctcgttgtga gagaaagtat tgattttttt gattagctga
    37141 ttacgtaact ctgtaccaaa tccttgtgaa gctactgaag catagtattg gcaaatgata
    37201 gcacaaatca gaccaatcac agacatagcg accatccata agcccatttc aatgattttt
    37261 cctcggtcat tcatttttag tccattatcg atcaaggaag ccatcattaa aggcaggaca
    37321 agttcgaaga cagcttcaag aaatttgaag aacgggccca aaatgatttg cttacgatag
    37381 tcttttgcat aacgtaataa ctgaatcata tgattcctcc tattatttat ttgtccacaa
    37441 ttgaaaaaac aagtactacc acattgtagc ttaggaaatt tagaatgaaa agagaacaag
    37501 ccttttcata aatgaaagtt ttattatgaa gaagctttag aaattgaata gactattttt
    37561 tttaaaaaaa agaaaatgag aaaacatgcc agtctcttca ttcataggaa cgtctatttt
    37621 acttaatttt tctataaatg aattctgcat aaaaaatata tcaagtaaat gtttatagat
    37681 gaaactctat ttacttcttt tttaatttgt tcttgcaatc ttttttgcta cgtaattttt
    37741 gtaaaaaagt gggttgagag aaatctaatt gattttcaaa gaaggagtat gaaaatgaga
    37801 aaaatattta ttcgtttatt gtgggtacta tcttagagga ataaataata gtggagaaaa
    37861 ctatggtttg gcgcagattc tatcaggttt gatggaacga agacaacctc ccgacatcaa
    37921 gtcaaaagct acttgagatt ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc
    37981 aatgtttcta ccttgttttc gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca
    38041 ataaaaagga tggtgacaac agtacctctt tactctctga aagcatcata actcgttttt
    38101 cctcattatg ccaataaatt gttgttatac cacatataag gatttgtaat agctaaaaac
    38161 agacaggaaa gttgaaatct gtgaatctta ttttgtatgg aaggatttat agaacgcaaa
    38221 aatcaagata aagatgaata aaaatcctgt ttcggctata tattgcgtat ctacgccaat
    38281 aaaacgagtt tgttctgtca tagccatata aagcaaaggc aaaaatacaa ctacagcgag
    38341 ataagatccg atgatttctc gaaaagtttt ccaggaagta tgtttcctgt ttttatattt
    38401 atccgatttc attgaatagt catagcctcc ttattctttc atatgttgaa attccagtat
    38461 aaaaactgga aggaactgta cgttttttag aataaaaatt ataagggata agtaggctgc
    38521 tgtctataat aagatatatt tttcaattct ttattaaaga ttttattgac aaaatgaatc
    38581 cgttttctat gatggaggag gggtgaataa gttgttgaag aaggaaattt tatgttactt
    38641 agagaaccag acagcctttt tcgatttaga acatatgaac gaggtcttta cagcacaaag
    38701 gttagctgat cattttgggg taaaaagaaa cacagtcagt cattatttga accagttaaa
    38761 tgatgagcaa ctactagtca aaatcaattc tcgaccagtg atttatttcc acaaagaagc
    38821 ttttgaaaaa caatttttta agttacgcac gaatttttat ttttctatcg atgatctcaa
    38881 agaggaacag ccttttttcg cgcaaccaaa agacttattc tcttttatga tcggatacga
    38941 cgccagtttg aaagaaagta tcgaacaaat caaaacagct ctttactatc cagatggcgg
    39001 attaccactt ttgattacag gcgaaagtgg cacaggtaaa agttatttag ttaatttggt
    39061 ctatcagtat tgtctgcttc atgatctgct agaagattct gcaccattca tcacttttaa
    39121 ttgtgcacaa tatgcagata atcctgaact tttgactagc aatttgtttg gacatgttaa
    39181 gggagcgtac actggtgcag aagaaaataa aaaaggggct tttgaagcag cagatggtgg
    39241 gatcttgttt ttagacgagg tacatcgctt aacaccagaa ggtcaggaaa aactgttcac
    39301 ctatcttgat caaggtgtga tttatcgtat gggagaacct aatttgtcgc gccggatcaa
    39361 aacacgtctc ttttttgcta cgactgaaga gattactagt catttcttaa caactttcat
    39421 tcgaagaata cctatccgaa tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg
    39481 gctagaactg atttactctt tttttctcga agaacaaaga aaaatgggga gccctttgtc
    39541 agtcagtgga ccagctttgt cacttttaac aagtcagaaa ttatccggaa acataggaga
    39601 gctgaaaaat atcgtcaaag tttcagcagc aaaagcatat gctgaacagc gtgaacagcc
    39661 tgaaatccat gtcacgatcc atcatttgca aaaagaacta cttgcgcagc ctattactaa
    39721 aaatacagca cagcaaggaa tctatattac gcaagaccag accttagagc aattaatgga
    39781 gaagcaacag cccgaacagc agcgaatcgt taaaagtttt gagcaaatcc taattgattt
    39841 caagaaaaat aactgtctgc tatattcttg cgaaggaaaa ttaaagcaag aagtgattca
    39901 attatttgat tttttgctgt ttgagaccag tagacaagaa aaacacgagc tgctggttta
    39961 ttggacacaa tctatccgag agacctttcg acaaatggaa actgcctatc aaatcaaatt
    40021 cgatggaaac agtgtctatg ccttgagtta ctatctctat cagcgaagca ctatcaaatg
    40081 gttaccggaa gaacatgata ttatccaact aatcaaagaa ttagaacaac aagtttctca
    40141 gtcttatcca tctagttatc actatgtcca acgaattctg gaattaagta agatcaaatt
    40201 agatattgaa gacacaagta tggatcggat tttactgacg atctatctaa aaaaagcgaa
    40261 atggtcaaaa gaaaaacgac tgccaaaagc gatgattgct gctcacggtt atgcaactgc
    40321 tagcagtatg gcaaatgtag taaatcgttt attacaagag gatctatttg aatcatttga
    40381 tatgccacta gatgtcacac cacagcagat tgcttcagaa atccttgatt attgcgaaaa
    40441 cagcgatgtt tcaaatggat tgatcatatt agtagacatg ggatctctga aagaaatcca
    40501 tcagtttttt aaaaaacagt tatccgtacc gcttttgatt ttgaataatg tgacgacacc
    40561 tttagcaatc acagtagggg aatgcctgca aaaaaatgta tcattagaag agatagcaga
    40621 agagactgtt cgacagatcc agccagaatg gcgactgctc tatccagagg aaaacaaacc
    40681 caaagcactc attactactt gcttcactgg aatcggtacg gcggtccact taagtgaact
    40741 gctagaaaaa agcttaccta cggcttgtca gttgaaaatc atcccatatg aatatcagca
    40801 attaaaagat aagaaaaaca gtgacccatt attttccata tacgaagtcg taggaatgat
    40861 tggcaccaca gatcctgata tcaccaatat cgactatctt tcattagaag acctcatctc
    40921 gggggaaaag atgtctgtac tagctgaatg gttggacact actatgaatg cttcagagaa
    40981 ggaaatattc aatcagcgca tcattcgtaa tttttcattg gaaaaagtac tggattccgt
    41041 gactattcta gatacagaga aggtgatggg agaaatcgat cattttatga gagaattaga
    41101 ggtgcagttg aatcgaagca tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag
    41161 ctgtctcatt gaacgattga tccgacaaat gccaatcgaa acctatcaag gattagagaa
    41221 atggaagcag tgtcaaaaag aagggttatc tgctattaaa tctgcgttta gtgtcattga
    41281 agagcattat agtgtcatga tccccaattc tgagattgcc tatatctatg atattttgag
    41341 tgaagataca gagtttctct cgatagaaga agaattttga acataagcaa gttgttgcca
    41401 ctaattttgg catgcaactt gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa
    41461 gtggatagag aaattatctt agcttcccat ggaaaatttg cttcagggat attagattca
    41521 ttagagctga tctatgggaa aaatcattct attactgtat tcgattgcta tactgatgag
    41581 aattttgatt tagcggaaac agtaaggcag ctttttatga ggtacaaaga taaagaaatc
    41641 attgttctga cggatctttt tggcggaagt gtcaacaacg aattcttaca atatatcaat
    41701 cgggatcatg tctatctcgt tgccggattg aatttgccac tattgattga gctagtatct
    41761 cggttggacg ctgaagtaga gacaactgtt ttgatccagc aggtgctaac tgattcaaaa
    41821 aaaatgatcc agttttgtaa cgagcggctc aatcagaaaa tagaagaaga cgaattttag
    41881 gaggaagaaa aatgattgta ttgacaagag tcgaccatcg gttattacac ggacaagtag
    41941 ctttttcatg gacacaaaca ataggcgcag actgtatttt gattgctaat gatgatgtac
    42001 ctacgaatga gatacgaaag acaacgatca aattagccaa gccacaagga gtcaaactag
    42061 tgatcaaatc aattgatgac tcgattgccg cgttgaaaag cggggtgaca gataaatata
    42121 agttattcat cgtagtggaa tcgatcgagg atgcatataa gctggcagaa gcgtatccag
    42181 aaatcaaaac catcaactta ggagggatca aggcaaaacc tggtactcgc agcatcggaa
    42241 aagcggtaaa tattttacca gaagaggagg aacgcttgaa acgattaatt gacaaacaaa
    42301 tagaagtaga aatccgtcaa gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt
    42361 aagaaaggaa gaacctcaat gattgtacaa gcagtcttat taggaattgt tgcatttgtc
    42421 gcacaatcag aatatgcact agggacatcg ttgctttctc gtccgattgt gacggggctg
    42481 tttacaggaa tcgtgttagg tgatgtaaaa actgggatca ttatgggcgc aactttagag
    42541 ttagcattta tcggatcgtt ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt
    42601 gggattttag ggacggcttt tgctattaca gctggagccg gtacagaaac cgcgctttta
    42661 ctaggtttgc cgattgctac gttgacattg atattgaaaa atatttactt agggcttttg
    42721 attccaatta tgaaccataa agcagacaat tatgcagaag aaggaaatta taaaggagtc
    42781 gagcatatgc acttgcttgc cggtatcggt ctttccttga tgcttggtgt tgtggtaatg
    42841 gtttcttata tggtgggaag caatacgatc ggaaatctat taaatatgat tcctgacttc
    42901 gttcaaaagg ggttgtcagt agctacaggg ttgattccag ctcttggttt tgcgatgctt
    42961 gctcgtttgc tgatcaacaa acaagttgca ccatattttt tcttaggttt tgctatagct
    43021 tcttacttag agattcctgt gaccggagta gctatttttg gtgcgatttt agcagttgtg
    43081 gtagtcaata ttatgaatgt ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa
    43141 gaagatgaag aattctgaga tcaaaaacag caaaataacg aaaaaagagc taaatcacgt
    43201 attttggcgt tcttttcaaa tggagttttc ttggaattat gaacgtcaga tgaatatggc
    43261 ttatgtttat gcaatgattc cgattttgaa aaagttatat cagtcgaaag aagaaatggc
    43321 agcagctttg aaacggcatc tagagttttt taacacgacc ccacatatcg ttacactgat
    43381 tttaggaatc acggctgcaa tggaggaaga aaataaggat gatcctgaat ttgatgtgac
    43441 tgcgatcgat agtatcaaaa catctttgat gggacctctt gcagggttag gagattcttt
    43501 cttttgggga actttgcgat tgattgccac aggtgtgggt acctctttag ccatgcaagg
    43561 aaatatttta ggccctatct tgttcatttt gattttcaat attccgcaca ttctgtttcg
    43621 ctatctagca acaggttggg gatatcgctt aggaacgggt tttttgaaaa agatccaggc
    43681 aaacggtatg atggaaagtt tgacattagg cgcgtctatt attggactga tggtcgttgg
    43741 agcaatgact gccacgatga tcaccatcaa tattccttta aaaatcggtt caggagaaaa
    43801 tgctgtgact gttcaaagta tttttgatga tatcgttcca aatatcttat gtcttggagc
    43861 atttggcata gtgttttatc tattgaagaa agaagtgaaa ccattaacga tcttgatcgg
    43921 actagctttc tttggaattt ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga
    43981 aaatgtttac gatgcaagat tatatctatg aagaaaagga agtactaagt acgatcttga
    44041 aaaagaatga tttttcgaca agagaacata tgaaaaaaac agtgaattta ctgatcttag
    44101 caacgggttc atcttataac gcttgtttag cagcgaagcc agcattggaa tcttatggtg
    44161 atcttactgt cgatattcaa gaaccttttt attttttcaa ttatggaaaa ctttctcctt
    44221 caatcgatac tgtgattgct gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag
    44281 taaaaatgat acaaaaacaa gggttacctg ttgttgctat cacaaatgac gtgcaaagtc
    44341 cacttgcttt agaagctgca caaattattg atttaggtgc cggggtagaa tcagtaggct
    44401 tcgttacaaa aggctattct gcgactgttt tacagttact actcttaggg ataggaattg
    44461 gaataagtaa aaataaaatc agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca
    44521 aaataatcaa ccatttacca gcgattattc aaaaaacgga agaatttttt gatggatatc
    44581 aaagtttatt tcgtttagca cagcgtttcg tcaccattgg atatggtcca aactggggaa
    44641 cagctaaaga agcagagacg aaattgactg aaacaatccg cgttccgtca caaggatttg
    44701 agttagaagc ttatatgcac ggcccatacc tggaggcaga tgcttcgcat ttgctattct
    44761 ttattgaagg ggaaagtgta aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc
    44821 ggtacgttgg agagactctc accattacca caaaaaaagc aagaaacgag aaaacacttg
    44881 gattagcaat agaatgtgat gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac
    44941 tattcgctta taaaaccgca gtagctaaag gtattgactt gaacaaaaag atttttgaag
    45001 actttgatac agtcttgaaa agtaaattat aagaggtgga aatcatgctg aaattcaatg
    45061 aagaagaaca aatcaaagca ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa
    45121 tcatcgataa actttatgcg gaaaaatttg acgctgtcta ttatctagga atcggtggaa
    45181 cgtatgcttc ctcgatgcaa gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct
    45241 ttgtacagca tgctgcagaa tattacacta ctggaaacaa aagattaaca aaagattcta
    45301 tcgttatttt gtcctctgtt accggtacaa ctcaagaagt agtgaaagca gtagaacaaa
    45361 tcaagaaagt aggagcgaca ctgattggat ttatcgataa agcgaacagt aagttgtctc
    45421 agctatgcga ttttgtggtc acttatccag ctcctggaac agaacaaatc aaatttttta
    45481 tggcagcaga tcgattgatg tatttgaatg gagaattcga agcttattca gaatactatg
    45541 aacagctcga acgttattta ccaacagggt tagtggaagc agagaaaaaa gcagatgcat
    45601 ttggcttatc atttgcagaa aaacatcgac gtgatagtat gcattatttt attggagcag
    45661 ggaatcaatg gggagctgtt tattcatatg ccatgtgtta ctgggaagaa caaagctggc
    45721 ttccatcgaa atctatccat gctgccgagt ttcttcacgg gacgttagag atcgtagaag
    45781 aaacaacccc agtcacatta tttttaggcg aagatgaaca gagagtgtta tctgaacgtg
    45841 tggctaaact tttgccaaaa atttgcagca attatacatt gatagacaca aaagactatc
    45901 cagtagaagg tatcagtgaa aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg
    45961 tagtgacaca acgcatcgat gctcatgtgg agcagttgaa ctgccatcca ttagagatac
    46021 gccgctacta tcgtcagttt gattattagg atagactgga taaaaagaat ataaaaaata
    46081 aagagagcag cgataactgc tccctttatt tttttaaaat attggcatca attacgttat
    46141 aaaacaca
//
LOCUS       DARPZJ010000017        44952 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.017, whole genome shotgun sequence.
ACCESSION   DARPZJ010000017 DARPZJ010000000
VERSION     DARPZJ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.017"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            212..604
                     /locus_tag="SLE23_001194"
     CDS             212..604
                     /locus_tag="SLE23_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8468111.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="SLE23_001195"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="SLE23_001195"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEI8468112.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="SLE23_001196"
     CDS             3165..4775
                     /locus_tag="SLE23_001196"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEI8468113.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="SLE23_001197"
     CDS             5067..5936
                     /locus_tag="SLE23_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEI8468114.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="SLE23_001198"
     CDS             6101..7372
                     /locus_tag="SLE23_001198"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEI8468115.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="SLE23_001199"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="SLE23_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HEI8468116.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="SLE23_001200"
     CDS             8763..9026
                     /locus_tag="SLE23_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEI8468117.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="SLE23_001201"
     CDS             9471..9920
                     /locus_tag="SLE23_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8468118.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="SLE23_001202"
     CDS             9977..11395
                     /locus_tag="SLE23_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8468119.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="SLE23_001203"
     CDS             11395..12255
                     /locus_tag="SLE23_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HEI8468120.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="SLE23_001204"
     CDS             12429..13202
                     /locus_tag="SLE23_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8468121.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="SLE23_001205"
     CDS             13349..13714
                     /locus_tag="SLE23_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HEI8468122.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="SLE23_001206"
     CDS             complement(13862..15070)
                     /locus_tag="SLE23_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8468123.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="SLE23_001207"
     CDS             complement(15089..15367)
                     /locus_tag="SLE23_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468124.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="SLE23_001208"
     CDS             15521..16216
                     /locus_tag="SLE23_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEI8468125.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="SLE23_001209"
     CDS             complement(16658..17455)
                     /locus_tag="SLE23_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HEI8468126.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="SLE23_001210"
     CDS             complement(17452..18636)
                     /locus_tag="SLE23_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEI8468127.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="SLE23_001211"
     CDS             complement(18661..19908)
                     /locus_tag="SLE23_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEI8468128.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="SLE23_001212"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="SLE23_001212"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEI8468129.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="SLE23_001213"
     CDS             21888..22202
                     /locus_tag="SLE23_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEI8468130.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="SLE23_001214"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="SLE23_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEI8468131.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="SLE23_001215"
     CDS             22887..23531
                     /locus_tag="SLE23_001215"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEI8468132.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="SLE23_001216"
     CDS             23546..23875
                     /locus_tag="SLE23_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HEI8468133.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="SLE23_001217"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="SLE23_001217"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEI8468134.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="SLE23_001218"
     CDS             24863..25687
                     /locus_tag="SLE23_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HEI8468135.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="SLE23_001219"
     CDS             25680..26027
                     /locus_tag="SLE23_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEI8468136.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="SLE23_001220"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="SLE23_001220"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEI8468137.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="SLE23_001221"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="SLE23_001221"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEI8468138.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="SLE23_001222"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="SLE23_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEI8468139.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="SLE23_001223"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="SLE23_001223"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEI8468140.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="SLE23_001224"
     CDS             31657..32451
                     /locus_tag="SLE23_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468141.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="SLE23_001225"
     CDS             32441..34483
                     /locus_tag="SLE23_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468142.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="SLE23_001226"
     CDS             34764..34913
                     /locus_tag="SLE23_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEI8468143.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="SLE23_001227"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="SLE23_001227"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEI8468144.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="SLE23_001228"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="SLE23_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEI8468145.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="SLE23_001229"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="SLE23_001229"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEI8468146.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="SLE23_001230"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="SLE23_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEI8468147.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="SLE23_001231"
     CDS             39330..40412
                     /locus_tag="SLE23_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEI8468148.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="SLE23_001232"
     CDS             40412..41215
                     /locus_tag="SLE23_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEI8468149.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="SLE23_001233"
     CDS             41285..42025
                     /locus_tag="SLE23_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEI8468150.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="SLE23_001234"
     CDS             42036..43040
                     /locus_tag="SLE23_001234"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEI8468151.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="SLE23_001235"
     CDS             complement(43085..44929)
                     /locus_tag="SLE23_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468152.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14456 a         7838 c         9350 g        13308 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcgcgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac tt
//
LOCUS       DARPZJ010000018        44717 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.018, whole genome shotgun sequence.
ACCESSION   DARPZJ010000018 DARPZJ010000000
VERSION     DARPZJ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.018"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="SLE23_001236"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="SLE23_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEI8468153.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="SLE23_001237"
     CDS             complement(322..891)
                     /locus_tag="SLE23_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEI8468154.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="SLE23_001238"
     CDS             1077..1979
                     /locus_tag="SLE23_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8468155.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="SLE23_001239"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="SLE23_001239"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEI8468156.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="SLE23_001240"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="SLE23_001240"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEI8468157.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="SLE23_001241"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="SLE23_001241"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEI8468158.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="SLE23_001242"
     CDS             8547..8732
                     /locus_tag="SLE23_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HEI8468159.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="SLE23_001243"
     CDS             complement(8794..9990)
                     /locus_tag="SLE23_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEI8468160.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="SLE23_001244"
     CDS             complement(10160..11596)
                     /locus_tag="SLE23_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEI8468161.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="SLE23_001245"
     CDS             11889..12698
                     /locus_tag="SLE23_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8468162.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12884..15037)
                     /locus_tag="SLE23_001246"
     CDS             complement(12884..15037)
                     /locus_tag="SLE23_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEI8468163.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15432..16280)
                     /locus_tag="SLE23_001247"
     CDS             complement(15432..16280)
                     /locus_tag="SLE23_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8468164.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16504..18444)
                     /gene="thrS"
                     /locus_tag="SLE23_001248"
     CDS             complement(16504..18444)
                     /gene="thrS"
                     /locus_tag="SLE23_001248"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEI8468165.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18781..18960)
                     /locus_tag="SLE23_001249"
     CDS             complement(18781..18960)
                     /locus_tag="SLE23_001249"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEI8468166.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(19007..20830)
                     /gene="cadA"
                     /locus_tag="SLE23_001250"
     CDS             complement(19007..20830)
                     /gene="cadA"
                     /locus_tag="SLE23_001250"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEI8468167.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21108..23387
                     /locus_tag="SLE23_001251"
     CDS             21108..23387
                     /locus_tag="SLE23_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8468168.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23480..24127)
                     /locus_tag="SLE23_001252"
     CDS             complement(23480..24127)
                     /locus_tag="SLE23_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468169.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24306..25025)
                     /locus_tag="SLE23_001253"
     CDS             complement(24306..25025)
                     /locus_tag="SLE23_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8468170.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25156..26307)
                     /locus_tag="SLE23_001254"
     CDS             complement(25156..26307)
                     /locus_tag="SLE23_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEI8468171.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26524..27264)
                     /locus_tag="SLE23_001255"
     CDS             complement(26524..27264)
                     /locus_tag="SLE23_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8468172.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27268..27591)
                     /gene="rsfS"
                     /locus_tag="SLE23_001256"
     CDS             complement(27268..27591)
                     /gene="rsfS"
                     /locus_tag="SLE23_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEI8468173.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27648..28241)
                     /gene="yqeK"
                     /locus_tag="SLE23_001257"
     CDS             complement(27648..28241)
                     /gene="yqeK"
                     /locus_tag="SLE23_001257"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEI8468174.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28225..28875)
                     /locus_tag="SLE23_001258"
     CDS             complement(28225..28875)
                     /locus_tag="SLE23_001258"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEI8468175.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28885..29196)
                     /gene="yhbY"
                     /locus_tag="SLE23_001259"
     CDS             complement(28885..29196)
                     /gene="yhbY"
                     /locus_tag="SLE23_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEI8468176.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29212..30321)
                     /gene="yqeH"
                     /locus_tag="SLE23_001260"
     CDS             complement(29212..30321)
                     /gene="yqeH"
                     /locus_tag="SLE23_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEI8468177.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30318..30845)
                     /locus_tag="SLE23_001261"
     CDS             complement(30318..30845)
                     /locus_tag="SLE23_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEI8468178.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(31025..31810)
                     /locus_tag="SLE23_001262"
     CDS             complement(31025..31810)
                     /locus_tag="SLE23_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEI8468179.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31803..32672)
                     /locus_tag="SLE23_001263"
     CDS             complement(31803..32672)
                     /locus_tag="SLE23_001263"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEI8468180.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32673..34052)
                     /locus_tag="SLE23_001264"
     CDS             complement(32673..34052)
                     /locus_tag="SLE23_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEI8468181.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(34060..34479)
                     /gene="fabZ"
                     /locus_tag="SLE23_001265"
     CDS             complement(34060..34479)
                     /gene="fabZ"
                     /locus_tag="SLE23_001265"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEI8468182.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34504..34980)
                     /gene="accB"
                     /locus_tag="SLE23_001266"
     CDS             complement(34504..34980)
                     /gene="accB"
                     /locus_tag="SLE23_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEI8468183.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34983..36218)
                     /gene="fabF"
                     /locus_tag="SLE23_001267"
     CDS             complement(34983..36218)
                     /gene="fabF"
                     /locus_tag="SLE23_001267"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEI8468184.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36237..36974)
                     /gene="fabG"
                     /locus_tag="SLE23_001268"
     CDS             complement(36237..36974)
                     /gene="fabG"
                     /locus_tag="SLE23_001268"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEI8468185.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36986..37903)
                     /gene="fabD"
                     /locus_tag="SLE23_001269"
     CDS             complement(36986..37903)
                     /gene="fabD"
                     /locus_tag="SLE23_001269"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEI8468186.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(38010..38234)
                     /locus_tag="SLE23_001270"
     CDS             complement(38010..38234)
                     /locus_tag="SLE23_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEI8468187.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38287..39249)
                     /locus_tag="SLE23_001271"
     CDS             complement(38287..39249)
                     /locus_tag="SLE23_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEI8468188.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39259..39699)
                     /locus_tag="SLE23_001272"
     CDS             complement(39259..39699)
                     /locus_tag="SLE23_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8468189.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            40005..40970
                     /locus_tag="SLE23_001273"
     CDS             40005..40970
                     /locus_tag="SLE23_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEI8468190.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(41027..41257)
                     /locus_tag="SLE23_001274"
     CDS             complement(41027..41257)
                     /locus_tag="SLE23_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEI8468191.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41343..42230)
                     /locus_tag="SLE23_001275"
     CDS             complement(41343..42230)
                     /locus_tag="SLE23_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEI8468192.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42319..43542)
                     /locus_tag="SLE23_001276"
     CDS             complement(42319..43542)
                     /locus_tag="SLE23_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEI8468193.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43559..44605)
                     /locus_tag="SLE23_001277"
     CDS             complement(43559..44605)
                     /locus_tag="SLE23_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEI8468194.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
BASE COUNT        12644 a         9671 c         7747 g        14655 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa ttttaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc
    12781 agtttctcgg tatgaagtca aatttaagca aaaatgtgag aagctatttt cacaaaattt
    12841 ttcttcatac tcgaaactaa gcggcttttt cacgacctct tttttatttt gccatgaaca
    12901 tatcataata cgcgtccatt atttctttag caatcgtcaa gtttatgtgg tcttgttcgt
    12961 ctaataagtt cggcaagaca acactgatgg caatttccgg attgtctgtt ggtccgtatg
    13021 ccacgatatt actattgact gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag
    13081 tccctgtttt tgcggaaagg tccattttcg cactggctaa tggtttggct gttgtgtaag
    13141 gatcggtacc atggacaact tggtggaatc cttcacggag gatcgccata ttttctgcag
    13201 aaatattgac cgtattttct actgttgtgc caatttcttt cttcacttca cccaagtttc
    13261 cattttcgtc attgccatag atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat
    13321 tagcgactgt tgaagcatat tgagctaatt ggattggtgt atatgtgtca aactgtccaa
    13381 atgccaaatc ggtaaagtta cctggagcat accattcttt gccattatcc gcattgaact
    13441 tcttcatata atcaacagaa cgtgagatcc caggagattc attcggcaaa tcgatcccag
    13501 tcgttgtacc aagaccaaac tctttgaaag agtctctcaa ttgctgataa gctttagctt
    13561 cttcatctaa actaggtagt cccattccag gtgtatagtc tagtcctaac atctttaacg
    13621 ccactttgat catatacgta ttagaagaca attccgatgc tttgactgca tcaagagcaa
    13681 cttgtccgct tcgattaaag acagagcttt tttctgaagc accttgcaga cgaatcggct
    13741 catcaatcaa aacttgattt ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac
    13801 cagccttgac tacagaccct ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg
    13861 tgatttcttt ggaaccttgt tcatgactga aaccagtcat tgctagcact tctcctgtct
    13921 gaggattcat agccactgca taagcaccag gcgaatactg tgctttgccg ttgttgatca
    13981 atgtttgata attccttttc aaaatttctt ctacttttga ttggaattct gcattcatag
    14041 ataacattaa attagaacct ttttccccag agaagatttc tttttgattc gaaacatttc
    14101 cttcattatc aagggaaact tcatattggg ttttggttcc ttgcaggaca tcttcatatt
    14161 gtttttccaa ataactttgt cctacacggt cattccgaga ataacctttt gctaggtatt
    14221 tctctgcttc atctgctgga agtccttgct tttcagtcgt cacactgcca agaatacttt
    14281 tcagtgaact tgctgcatta tattctcgtg tccagtctgt gccagtcgaa actcctggaa
    14341 gttcagaagc gcgttctgcc acaacagcta actcttgatc agtaacacca gagtttttga
    14401 tatagacagt gtttaattca tatgcactat tcatccgttt aaagatggta gcaattttta
    14461 attgctcctc gtttaaatta atctcatcag ctgtgacttt attgaccatc gcactatatt
    14521 gttcgctgtt ccctaattgc ttttcttttg ccgaaagtct ttttgtggct tctttcaaat
    14581 gtttgggatc agccagccaa aaatcttttt tatctctatc tgtcagattt tcatctaccg
    14641 gaacatcgat cagcgagttc agcttcgttg cgatttcaag caaatcttta gccgtaactt
    14701 gtgttcctct cgtatatgtg atggcctgat tcgctttatt cgtaactaaa gcttttcctg
    14761 tggagtcgta gatcattccg cgaggagtac tttcttggac cgtaatcgta gaagtagact
    14821 tcactcgcgc ctccatctct tcgccgttca cgatctgcaa ataacccaat ctagcaatca
    14881 acgcaacaaa taacgtaaat ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg
    14941 accggcgaaa cgttttgttc ttaggttctt gtgcaccttt tcttattttt tctaaccaag
    15001 aagtatttaa tatttttttc ataaaatctt tcatcatttc ctatccttcc gcctatttac
    15061 attcatgctt cattgtaccc aaaaacttct taataaacaa gaagtattta atattttttt
    15121 cataaaatct ttcatcattt cctatccttc cgcctattta cattcatgct tcattgtacc
    15181 caaaaacttc ttaataaaaa agaaaaaatg ggcggagcaa gaaattcttt acctaatttc
    15241 aagataaaat caactttttg tttcacagca atcacttaaa gttacatatc caactatttt
    15301 tttcattaaa aaataaactt atttttgaaa attatgtttt cttaagtcgt gaaacacttt
    15361 gatggatcat ttatttgtgg aaaactacgt tttgttattc taaaaaactt atataaaaaa
    15421 tagtaaggtt tttatttcga atccataaaa tattcttgga ttgcttctcg tgtttttttc
    15481 actttttcgc taagcttttc gtttttagcc atatagaaat aaaaaatgat atcgatcgta
    15541 gcaaattggg ccaaaagtga attagttgcc gcacttcgat tcgtgatttc ttttggtcta
    15601 gatgtttgta cgagtacatc ggctatcttg ctaagcgggt tatttccaaa ttgcgtcaac
    15661 gcaatgattt cgatattcat gcttttcgcc agctcggcta atgcgactac atctgcactt
    15721 ctacctgagt ttgaaacaag ccaaagcact ttctttttct cattgctgac aagttgcggg
    15781 agcaagacgt ggatatcttt ttcaaaaatg attggcttac cgacacgaga ccatttttgc
    15841 agaatatctt ctactactaa agaagaggcg ccaaccccat ataaaaaaac agtctctgcc
    15901 gattccaaac actctacgac tttttggatc gtttcttctt ctagaatatc tactgtttct
    15961 tttatcgcta cttgtgcatt gttaccaagt ttgtttttga tagagtaaaa ggactcattt
    16021 gcttctatat cactaaaacc ttcatcgatt ccagtctgta gttctgttga aatcgtgatt
    16081 ttgaagtccg tcagactttg aaaaccgatt tttttggaaa aacgtacaac tgtcggcgca
    16141 ctcaacccgg aagcttctgc taattcatta gctgtcattg tagggacctt ctcaatatta
    16201 ccgataatgt agttggccaa ctttttttct gctgaagaat aatcttccat catactttca
    16261 atacgactaa ttacgctcat aagttcctcc acccttttaa tgatagtcta tgtaagtata
    16321 ccatatcaga cccttattca cggtcgtata ctggataaaa aacaaaaaaa caatccgccc
    16381 aacagaatat cttatcccat caatcccaca gattctattg agcatctgtg tctttgagga
    16441 atacctgtta tctattgttc ggattgcttt ctatctacta cttttttaca ggaaatttac
    16501 ctattagttt tctctgctgt aatttttgac ttctgcttcc atagcatcaa taaagatatt
    16561 caaatcttct acagctgttt ctttacttcc ataacgacgt acgttcactg ttgcatcttc
    16621 caattccttg tctccaacaa ctaattggta agggatcttt tgtgtttgag aggcacgtat
    16681 cttatagccc attttttcat tacgatcatc aacttctaca cgcaacccct tcatttgcaa
    16741 acgttctttg atttcataag cataatcgcc atgtgcatca acagaaacag ggatgattgt
    16801 tgcttgtata ggtgccaacc atgttggaaa agcgcctttg tatacttctg ttaaataagc
    16861 gacaaaacgt tccattgtag aaacaattcc gcggtggata actactggac gatgcgtatt
    16921 ttccccgtct tctccaacat atgtcaaatc aaagcgctct ggcaataaga agtctaattg
    16981 tatagttgat aatgtttctt ctgtaccaag agctgttttg acttgaacat ctagttttgg
    17041 tccgtaaaag gctgcctcgc cttctgcttc aaagtaatct agttctaatt catccatagc
    17101 ggctttcagc attgcttggg ctttttccca cattgcgtca tcatcaaaat atttatctgt
    17161 attgtttgga tcgcgatagc tcaagcggaa acgataatct gtaatattga agtcagcata
    17221 tactgccacc atcaattcaa gcgtacgttt aaattcatct ttgatttgat caggacgaac
    17281 aaatgtatga ccatcattca acgtcatttc tcgtacacgt tgtaaacctg acaaagcacc
    17341 tgatttttca tagcgatgca tcattcctaa ttcagcgata cgaattggta attcacgata
    17401 agaatggatc gtgtttttgt agaccatcat gtgatgaggg cagttcattg ggcgaagaac
    17461 aagcatttcg ccatctccca tatccattgg cgggaacatg tcttcttgat aatgatccca
    17521 gtgtccagat gttttgtaca actcaacatc tcccattatt ggtgtatata catgttggta
    17581 acctagacta acttctttgt ctacgatata acgttcgatc gtgcgtcgga ttgttgcccc
    17641 ttttggaagc cagaatggca aaccagaacc tacttctggg gaaaccatga acaagtcaag
    17701 ttcttttcct agtttacgat ggtctctttc ttttgcttct tcacggagac ggatatattc
    17761 tttcaaagct ttcttgtcaa aaaaggctgt cccgtataca cgttgcatca tttgattgtt
    17821 tgagtttcca cgccaataag cacctgccac tgataataat ttaaatactt gtatacggcc
    17881 agtggatgga acatgtggtc cacgacacaa atcgatgaat tcgccttgtt gataagcagt
    17941 aatcacttct tcttctggca attcactaat cagttctact ttgtacggat cacttgcaaa
    18001 aatttctaat gcttcctgtt ttgaaagaac acggcgttcg atcggcagat tttctttgac
    18061 gattttcatc atttctgctt cgattgccgg caaatcttct gcagttactt ggttttgtcc
    18121 attatctgta tcgtagtaaa accctgaatc gatagctggt ccaacgccaa agtggatatt
    18181 tggatagagg cgacgcatgg cttgggccat caaatgagct gctgaatgac ggactaagcc
    18241 aagtgcatct tcatggtctg gtgtgatgat ctcaatactt gcatcttcct cgattggacg
    18301 agtcaaatca acgagttttc cgttcacttt accagctaaa gctttttttg ctaagctttt
    18361 tgaaatgctt tcagcaattg ccaatgttgt tgttccagac tcaaattctt tgactgcacc
    18421 atctggaaaa gtaattttta tcataatagt ttcctccttg aaatgttttg attgatcaga
    18481 tcatcaagct gaaaaacaaa aaaatcctag catctcttga aaagagatac taggacgaaa
    18541 agttcgtggt tccacctaat gttcaaacgc aaatgcgttc ctcaagcgtt gtaacggtcc
    18601 gaccgccctt gcttcaacaa gggtttcgaa agtggtcatc ctttggtttt ctcctggaaa
    18661 agtttcagcc tagcttttcc tctcttatcg aagactctca aattcagttg gctttctcat
    18721 caatcaatta tgtgtttatt taaccactaa taaatagaaa aatcaagtgg gaaactaaac
    18781 ttattttttc cattccccat ttacaccgta tgttcctttt ttcatctcat tgatgatgac
    18841 atggatgtgt tcttttggtg cctgcgtgtt tttatgaaca gcttccgtga tatctttcat
    18901 catattttct aattgttccg gactgcgacc ttctactaat tcgacatgta cgaatggcat
    18961 aatgctctct cctctttctg atcgttcttt tttcaactcg attctatcat actatgtttg
    19021 tcttgggtac tgaatcagga aaaatggctg gatctttttt tgctctcaag gcactcaaaa
    19081 tagagaccgt atccacgact tcttgcaaaa cagctccgaa taatgcgggg attagtcccg
    19141 tacttgcaat taacatcaaa aaaatacaaa taaagatgcc aatcagtaca gactgtttcg
    19201 ctattctcat cgtatctctt gaaatcacta ctgcttttgc tacacgcaag agatcatctt
    19261 tcaagatgac cgcatctgca ctttcactag cagctgtaga accatgagcc cccattgcaa
    19321 taccgatatc tgcagcagca agtgctggtg cgtcattcac gccgtctcct accatcgcaa
    19381 caggtctttg atctttaggg atactttcta aaatggtcag tttatcttga ggcaagctac
    19441 gggcatgtac agaatctaat tggacttttt ctgcaatcgt ttgagcaatg gcagatccat
    19501 ccccggtgat catcatcaaa tttttcacat caagttttct tagctccttg attgtctttg
    19561 ctgcttctgg gcgaatctga tccgaaaata ggatcgttcc tgcaaaagat cgatcaattg
    19621 ttacatagat tgctgtattg gacgtttcta tttcttcagc tgaaacaaaa gaggcacgtc
    19681 caatctttac ttcatgatta ttgactactg cttggattcc ttgaccggtc acttctttca
    19741 gttgactaac aggatacagt tggctgtttt tcacgttgtt cactaacgaa cgagctaaga
    19801 tatggctaga ttcctgttct gcactagctg catacagaag tagctcttct ttttttattc
    19861 cattgactgg ctgaatcgcc tctacttcca atatcccttt ggtaagcgtt cctgttttat
    19921 caaaagcaat cgtttttgta cgtgcgagct tttcaatcgt tgttccagtt tttacaacga
    19981 tcccgttttt acttgaacgg ctcattcctg caactaaagc aatgggcgca gctagaatca
    20041 gtggacaagg tgatgccact accagtacct cagcaaatcg taaagggtct tttgagaacc
    20101 accaagaaat accaccgatc aaataagcaa tcaacgtgaa agggactgca taacgatcag
    20161 ctaaacggac aaatcgggca ggcttttctt ttgattcttc gactagttta ataatcattt
    20221 gatactggct gtctgcggca cgtttttcag cgatcatttg gatcgatccg tctccattta
    20281 aagaccctga cataatctga tctccaggtt tcttggtttc cgggcgggac tcacctgtca
    20341 aagaagattc atcgaccgaa gattctcctt tggtcactcg accatctgcg ggtacaagtt
    20401 cgccaggctt gactagtaac tggtcatcaa tatttatttc atcgattact atatcctgca
    20461 attttccttc tttgaatcga tgggcaattc ttggggtgtt atctaacaaa gactgcagtt
    20521 ctttacccgc tcgtttattc gcgtaatcct ctagactatc tccgcccgta agcatgatca
    20581 atatcatcaa actagcccag tattctttga cggctaatgt tgcaaggatt gcggtaatcg
    20641 ctaatacatc tacgccatat cttcctgaac gtaacgtctt gatcatttcc aaaaacatca
    20701 agaaggcgag aatccctcca gtaaatgcga caatcgcaaa tgcaagggcc ggctggtgaa
    20761 aaacaaattc acttaataaa gctatcccac caataagcaa agtaagtaaa aattttttga
    20821 aatgtgtcat tgttttttct cctcttttat gtgacttaga gaggttagta ataaatttcc
    20881 agctgcctct ttcatcttaa gcatagtcct tgactagcac tttttaaaac aataggcctt
    20941 aattgaaaac aactatcact atcagcgttt ccaaaattca tcagttctac aaacaaaaat
    21001 attcagcaag gattactttt tcgattcatc agttaaaaag tacctttttt cgaaaaacta
    21061 tgctatactt ttaattcgtt atttacggcg gaaggagcaa acatgcgatg aatgagaaac
    21121 aactagaaca aacgcacgtg gatgaaacga tcgaactaat ccagatcgaa caaaatatgc
    21181 tggatacaaa acaacaagaa ttgactcagg aaatgaatca ttcgacaaaa gacacagcta
    21241 atcacaagat tcgagctggt tccaatgaag ctttttatga atctgctgtt gaatatcgcc
    21301 aacatgagca ggaattgctt ttgaaatacc atactcttga agcacagcaa aaacgcctgc
    21361 aaacgttgtc tgtcatgaaa gatagtcctt attttgcccg tatcgacttt aaagaagacc
    21421 gtgaaacaga aacattatat ctaggtatcg cttctttaag agatctggca gaagaaacaa
    21481 tcgttattga ctggcgcgca ccaattgcca atctttatta tgaaggtgag attggtcccg
    21541 cattttatga aactgaaaca gatagaatag atgtcgatct gcagttgaaa cgacaattta
    21601 aaatccaaga aggacgtatt ttatctatgg tagatacgtc ggaagtaatc aatgatgact
    21661 ttttgctaga gatattggat gaatcatcaa gcaaccatat gaaaaacatc gtctctacga
    21721 tacaaaaagc acaaaatgca atcattcggg acacaacaag taaagtaatg ctgattgaag
    21781 gaatcgccgg aagtggaaag acatccgctt tgcttcaacg tattgctttt ctgttgtatc
    21841 ataatcgcaa gtggctcgag gctgaaaacg ttcttctatt ttcacccaac catttgtttt
    21901 ctgattacat ctcgactgta ttgccttcat taggtgaaag cggcgtgcct acacagacat
    21961 tcaaaaatta tttggtgcag ctgctgccag agttttcttt actagatgaa cagcaacaag
    22021 aaagtggttt tttgctaggg gaaaaagatc cgatacaagt gatgaaaagc ggattgacct
    22081 tagtcgatca gattgatcgc tatatccaag gcatcacaaa ctacggtccc ttgttccgtg
    22141 atatgaaaat aaatggccgt acgatcctat caaaggaatc gattcgccaa tggtataaag
    22201 aaacaaatga acaattacct ttacatcata gactttctct attacaaacg aagctcctga
    22261 aaaaattagg cggtctgcaa aaagacgaaa cacgtcagca atgggtcaaa gatctggcgg
    22321 aagaacagct ccaagaacta tacgcaacag atccaaatct tgaatataca gaacaaaagg
    22381 agcgttcatt acgtaaaaaa ctggccaacc aaatcgtacg taaaagattc cgtcgaatcc
    22441 atcgagggat catgaattat caatttgtca atataacgaa acaatatctc cactttctac
    22501 aaactgtgcc actttctctt ctaacacgac ataaaatcag cgagaccagg tggcaggaac
    22561 atttgacaac tgttcgtaca cacttgcgtc aaagagaatt gcgtcaagag gatgctgtac
    22621 tattcttttt actgatgcgc cgaacatatc cagtgacggt tacacacaaa gctcgctata
    22681 tctttattga tgaaatgcag gatttcgcac catcacaagt ggcattgctg caagccttgt
    22741 tcccaaaagc aaatttgact ttctgtggag atctaaatca aaatgtcttt ggaaatgaaa
    22801 cgatcgttgg atcattggaa gaccttttcg tggaccgtga agtcactcgt ttccaattaa
    22861 cgacaagcta tcgctccaca aaagaaatca ctgattttgc taatcatttt attgtgaaag
    22921 aacatcaagt agaaacaaca gcaagaaaag gagaccttcc tttgctcatc caaggaacaa
    22981 cagatgatat caaattgaat tggttagcag ataccattcg aacgactcag ggaaaagccc
    23041 ggtattggcg tacagcaatc atagctaaaa cacaagaaga atgcgaagct ctttatgctc
    23101 aactgccaga cgagttgaaa caacaagtcc agctgatttt aaatgagagt gactttatga
    23161 agcgttccat tattttactt ccagcctttt tagcaaaagg tctggagttt gaccgagttt
    23221 tcttgtggga tgtagatgca gaacattttt cttctcagca agacaaattg atcctttaca
    23281 ccatgtgtac acgtgcgatg catgaattga ccctttttac ctccaataat gaaagtcctt
    23341 tgttaaacaa tatggatatt tcatcttatg agaaaaaagt actgtaagta aaaagacaac
    23401 tgctatcatt aatgttagca gttgtctttt tatttacaat aataattgca gaaaaagtaa
    23461 ttcaatcatt taaggtcatt tattctatat ataaatccaa atctgtttca ggatatttta
    23521 atttgacaag cgaaataatc attttcagtt cttccatgtt ttctggatat tctgggtcaa
    23581 ataccttgct atgacggcca atcccgccat tgtcgatcaa tcggtaaatt cgattccatt
    23641 caatgaattg gtcaattgat tggaaattgc tgattggata gccgccacaa tccaaaatct
    23701 ctgatacacg aaatgctagg tatgcactat cgatcacttt attttttttc gtgtctatct
    23761 tctcatttct ttcgataaga attttttcag gacgatgttt caagctccac tctaatagta
    23821 gaaagaaagc ctccatccga tactcttctt caaataaccg aaaggctgaa tcagaacgac
    23881 gaaaaagcag cggaatcaga taattttgtc tataaatcag cattggtgcg cggtccacca
    23941 tacactctaa ataacggttc agataccctg taccgacata gtttcctaat cgatagcctt
    24001 caacgccgaa tcttgcgtat ttttgcgcta attttgaaca atcagttacg ttcacagcta
    24061 actcttctac tttgcggtaa ccgcttaaga tacgttcaaa aggttctaaa gtgatttttg
    24121 cttccatatt cttccccgtc catcttccac atacttcata tcatttcaca tgatacttat
    24181 gctctcatca taccacaggt tgaattagaa aagaaaataa atcacacaaa aaagcaagac
    24241 aatctgttag tgagattgtc ttgcttttcg aaaaagactg aatacttttc gttaaaactg
    24301 gttgcttagt cttctaatgc cacattatgg aacacatgct gtacatcttc tagatcttcc
    24361 agtgcatcaa tcattttttc aaatgtttct tgatcttctg gagatagtgt tacctcgttt
    24421 tgagggatca tttggatctc agcgattgaa aaatcagtga ttcctttttc ttttaatgct
    24481 tcttgtatac tatggaaatc cgctacttca ccgtaaacga tgatttgtcc ttcttcttcc
    24541 attacatcgc gaacatcgat gtctttttcc attaggtatt caaggatctc gtcagcgtct
    24601 tctcctgcaa aagcaaagat tgctgtattg tcaaacatgt aagaaaccgc tccggaaaca
    24661 cccatgttcc cgccattttt cccaaatgct gcccgtacgt ctgctgctgt tcgattcaca
    24721 ttgttcgtca atgtatcaac aatcaccatt gagccgcttg gtccaaatcc ttcatagcgc
    24781 aattcagagt atgtttcatc tcctgcacct tttgcttttt cgattgctcg gtcaataata
    24841 tgttttggta cattataagt tttagcgcga tcaatgacga aacgtagttt ttggtttgca
    24901 tgcggatcag gatcacctga ttttgctgcc gcgtagattt caatcccaaa ttttgcataa
    24961 atccggctat tattagcatc tttagcagtt ttctttgcta cgatatttgc ccatttacgt
    25021 cccatatttt cacttcgctt tctgatttga tagtttcata acgcaaaaac gtcctgttcc
    25081 attatacttg tgaatcacga ttctgtgaag ctttttttct ttcttccttc attcttctca
    25141 tttttagtca attatctata ctcggattgg gatttgcccg aaattctgtt ccggaatatt
    25201 gcctcccaat tgatagattt gatcacttct aactaacagt tccgcttctt gtgcctcttt
    25261 ttttccgatt cgggaataaa tagaaatctc ttttttttct tttaagaatc ttcttccagc
    25321 atcggtaaat ccaagtagtc gaagataatt tttattttgt tggacaggaa tctcttgctt
    25381 tttgatattc agcaagacat aacaagataa tcgttggatc cgtgtccatg tatatctttt
    25441 tgtttttacc tttgacacaa aatcctcaaa actatcagca gttgcagctg ctgttttcat
    25501 gcgcgattct attccttcgg tcatctgata gatatctgtc agttccagca aagtagaaga
    25561 taacaaccga taacgcaaat acggccaata agattcccaa gtctgcagcg aacaagttga
    25621 aagatcttct tctgtctgag gcggcacaag tccagctatt ctttttcctt cttctaacgc
    25681 atggcgaatg gctgttgcac tggctatcct ctgatctgtg atgatttttt catgatagcc
    25741 tgcactttta cgtcggatcg gatgtaattc catagggtgg acatacttgg cattttcctt
    25801 tgcataactt aatcccaaga tatgatttgg cgaagaaaaa tcaagcgtaa tatcgggata
    25861 cagactgcga aaaacctcag tcattttttg cggataacta tacgtttgat cagacagttc
    25921 ttgaaatgcc tcttctatcc tatcttgatt ctcttggaca aagcgtccga aactgctgta
    25981 atcaaacgaa gtctcttctt ctgttccaaa acacaaactg tcacagtcca gtgtttgcaa
    26041 gatttttact gcacctttag caaaatagtc agctgactga accgcccatt cgacgggaag
    26101 ctccactact aaatccacac cattttgtaa agcttcattc gcgcgatgcc atttatcgat
    26161 gatagccggt tcgcctcttt gcaaaaaatt cccgctcatt acagcaatga cgacctctgc
    26221 tcctgttatt tttcgtgcca tttccacatg atagcgatgt ccattgtgaa aaggattgta
    26281 ctctacgata atcccgcagc ttttcatgcg catcctcctt catagttatc gataaaaaag
    26341 aaatagagac aagtaaaaaa aggcaaaaat cggaaaaaat acccgaacta tataaactat
    26401 tctcgcaaac acaatacttc tgcgacgaaa agctgcactg caagagcaat gcctatatcg
    26461 ttcggatata taatttatgt tgaagattta ttcttttctt gttaactcga gcaggcaaaa
    26521 ccgctagtct ttgtatgcta caaagaacca gcgctttgat ttctctgatg ctgcttcgtc
    26581 tgtaaaatca gaaaatgctt cgactttcga aaagccgctg ttttccagca ttcttaaata
    26641 actttccaat ggataggtac gctcttgatg tagttcatct tcacgaataa atcgaccaga
    26701 cccttcttgt tcttcaacga aaaaggtaag aaaatgttcg atgctgtgtt tctcgcttcc
    26761 tggataacta tcccacaaaa aagcaaaatt atccccttga taatgatagc tatattctgg
    26821 aaaaacctca tctacttgat aggtggagtg tacgtcaaat aaaaatcggc cattttcttc
    26881 taacgcttga tagacttcat caaacacttg ctgtacctct tgtctatttt tcatatagca
    26941 cagcgaatca gaaaaacagg taattgcctg atattgtccg atttctgata aatcgagcat
    27001 attgccttcc acaaattgga tcgatgcgtc ttcttcatat gctcgctggc tggcaatcat
    27061 caacatctct tctgaaaggt ctaaccctgt cactttatat ccatcttttg caaaggcaac
    27121 cgctaatgct ccagtaccgc atgccagttc caaaatattt tttgtgtctt cttgtaaatg
    27181 acgtttcgaa aaagctaacc attgctgata aagtgtttcg tccatcactt catcgtaaat
    27241 gaaagcaaat gtttcataag ccatatgtta atccaaccat tcactaagat cgactagcgg
    27301 agcatctgac catagttttt ccagattata gaaatttcgt tctggcgcat ggaaaacatg
    27361 tacgatcaca tctccaagat cgatcaatac ccattttccg ccttcttttc cttcaatacg
    27421 ttttacttca tatttgtttt cttcttcttt atcaatgatt tcttctgtaa ttgcgttgat
    27481 ttgacgttcg ctatttgctg aacagatcat gaaataatct gccaacaagg aaacatttcg
    27541 aacgtctaaa gcgataatgt cttctgcccg ttttgaatct gctgcttcaa tcgcaatttt
    27601 taattgttct ttactatcta tgatgatttc ctcctaatat gagcagctta tttttttgct
    27661 acccagtaat tatatgtttc gattgttttt ggataaatct gttgttcttg cgcaagcaaa
    27721 tgggccaatg tatgttttgt ttcaaatgct acagcttcgt ctagatcagc ccatgcaatg
    27781 gctcgtgcat cttgtacccc aggaaaatct cgacctggtt caatatagtc tgctacataa
    27841 atgattttgt caaggagact catcttagca gccccagtcg tatgcacccg gattgcatga
    27901 agaatctctg catcggtgat tcctaattcc cgctctacaa acgaagcgcc aacaagacca
    27961 tgccagattg cattattata attcaataac tccggatcaa aaccgtctct tacgattacc
    28021 attttgaact cctcatctgg tcgttctttt gcataatcat gtgtcaatgc agcaatacta
    28081 gctttttcag gagaagcacc gtattttttg gcaagagcca cggctgtttc ttctactcca
    28141 agcacatgct tgaagcgttg ttcgctcatt ctcatctgta ttttttgcat caggttttct
    28201 ctagaataag cagtatattc attactatag tccatattca tacaaccctt cattttgaat
    28261 ataatcaatt actttatctg gaacaaggta gcggatagaa cagccttctt tgatcttttg
    28321 acgtattttc gtggaactga tgtcgatctc aggtacatct acccaaatta caggatatgg
    28381 agtatccgtt gtgtatcctg gtcgacgtat acccacaaag ttgaccatag aagtcagctc
    28441 atcgatttta taccattttg gcaaatattc taccatatcc ccaccgataa taaagtaata
    28501 atctgtatcc ggattgtttt gcgtcaattc cttcatagta tcataggtgt aacttttccc
    28561 accacgagct aattcaatcg tttcaatctg caaaaaagga ttgtcttcca ccgctaattc
    28621 caacatgttg agtcgatgtt ttgcatcaat cgtctgtttc tcatcaacat gaggtggctg
    28681 ataagaaggc atcaaaaata cgcggtcaag acctaaattc cggccagctt gttcagccat
    28741 cactaaatgt gcaaggtgaa cgggattgaa tgttccgccc aagatcccta cttgcttttt
    28801 cttctctaag aattgaggca tttcttcagg aaataattgt gaacgaacaa atgtcttagc
    28861 ttgcgtattc atcatggtca ctccttatat tgcttttact tcttttgata gcctttgata
    28921 cttttctttt gtggaaggtt tgtataatac aataacacgt ccaatgattt ggacgatttc
    28981 gcaatctatt tctttttcta atacttgagc tgcttcttct gcaatctcat ctgtattttg
    29041 aagtaacgat actttgatca gttctctttt ttctaaagct tcttcaattt gaacgatcat
    29101 tgctgaattg atcccacctt ttccgatttg aaaaatcggc tgaagatgat gcgctttgct
    29161 acgtaaaaaa cgcttttgtt ttcctcttaa actcataatt ttccttcttc cttaaatcaa
    29221 tgctttgcgt ttcaatacat ctacaccctt tggcgcccag cccgcaatta ctactggcgc
    29281 tgttacagtg atccagccta gaccggcaaa aacgatgtct gttttttctt tcacagaaaa
    29341 ctcaaaacga acaagctccg gaaatgcctc gacttcatca ggacgaggag gctgtaataa
    29401 tccacctaca tgtttttgat aaaattcgtc tgctttttcc agtttcgttc gatgaatatt
    29461 tacatcattt gacacataag caataaatga agcacgattg ccgctgataa aatcaaatct
    29521 tgcaagtccg cccaagaaaa gtgtttgccc ttcattcagc tgataaactt taggtttgat
    29581 ttcttttaac ggtgcaatga tccgcaaatc ttttttacct aagtagtgcg ccatttgatg
    29641 gcgatggata attcccggtg tatcaatcaa aaaatgcccg tcatctaaag gaatctcgat
    29701 tttatccaag gtcgttcctg gaaactgcga agttgtgatt acatcttgta ctcccgctgt
    29761 atttttgatg atttgattga taagcgtcga ttttccgaca tttgttactc cgacgatata
    29821 gacatcccgt ccatcgcggt attcttcgat tttttctaat agttccgtca tctcatgaga
    29881 tttcttagca ctagttaata atacatctac tggacgaatt cctgcttcgt aagcacgttc
    29941 cttcatccat tgtgttaatt tagttttttt caatgattta ggtaatatat ccactttgtt
    30001 cccaactaaa agtactggat tgtcaccgac aaaacggtgt agtcctggga ttagtgaacc
    30061 attgaagtca aaaatatcca ccacattgac gatcaatgca tctttttgcc ctaattcatt
    30121 cagtaagcgc aaaaagtcgt catccgtcaa tgagacatct tgggtctcat tataatggcg
    30181 taatctgaaa caacgctgac aatagacttc cccggaagct aaaccttttt ccaaagccgt
    30241 ttgcggcgtg tatcctaatt caccgggttt gtttgtttgt ataacggcac cacagccgat
    30301 acattgtaat tcttctgtca ttcgattcca cctcgccagc ccatatcagg gtgttttgct
    30361 aatagatagg ccataattct tttttcccaa aaacgattaa attgtgtctt ccaactatct
    30421 gttgcgataa tgggttttac aaggatgcta cgtatccctg cacgattggc tccacgtata
    30481 tcagtcataa tctgatcgcc taccattact atctcatcat ctgctaaatc caattgtttc
    30541 tttgctatgt tgatccctct tgctaaaggt ttcattgctc gtgcaacata caaaagatca
    30601 aatttttcaa tcgctcgcgc gacacgtttt gaattattgt ttgaaacaac aacaacaggg
    30661 attcctgcat ttttcatttc taaaatccaa gtaagcaact cttctgttcc atctggatta
    30721 ttccatgcaa tcaacgtatt gtctaaatcg gtcaatactg ctttgatgcc tagattcttt
    30781 aattgggcag gtgtaatctg atagatggct tctaccatcc atgttggttt gtaatttgaa
    30841 aacatgctgt ctcctcatct gcaaaaaatg aaggagcaca taaagtactc ctcaaccccg
    30901 tattatactg catatcagca aaaaaaacta cctctatact cgttcgtctt tcagaaaaag
    30961 catttcttta caaaatgacc aaaaataaag attgatcaca gaaaaattta gaaacaaaaa
    31021 acaactaata ttggcggaac ctcttgtatc gtttttccag taatttatgc tgatctaatc
    31081 gaacaagttc cgtcaatctt tcaatcaacg cttttttcat aatgtgtgcg actttatatc
    31141 gtggcaactg ctcgccgttg aacgtttcag gaataactcg atcaacgatt cctaactcgc
    31201 gtagttctgg cgcagtaatt ttcatcaact cagctgcttc tgcggcgcga ctaccgtctt
    31261 tccacaaaat cgacgcaaat ccttctggag aaagcacagc ataaatcgtt tcttccagca
    31321 tccagacttc atccgctaaa cctagagcaa gggcaccgcc acttccacct tcaccaatga
    31381 tgatggcgat gatcggtacc tttaaatcag acatttcgag cagatttctg gcaatagcct
    31441 ctccttcgcc gcgctcttct gctcctacac cgcaatatgc acctgctgta ttgatcaagg
    31501 taatcaccgg tctattgaac ttttccgctt gtttcatcag tcgtaaagct tttcgatagc
    31561 cttcaggatg gggagaacca aaatttctgc ggatattttc ctgcagatcc cgtccttttt
    31621 gaataccgat cactgttacc ggtttgccat ctaatcgagc gattccacca acaatcgctt
    31681 cgtcatctgc aaataaacga tcaccatggc attcctcgaa agaatcgaag atctcttcaa
    31741 aaaaatccaa gcttgtccat cgttctttag ctcttgctaa ctgaacgaca tcatgtgctg
    31801 tcttatccac gatctatcca tcctttctgt gtatgcaatt caagaagcgt atggattttc
    31861 tgtttcaatt ccatgcgggg aacaatctga tcgacaaaac catgagataa taagaattca
    31921 gccttttgga aatcttctgg aagttcctgc ttgatcgtct gttcgatgac gcgtcttcca
    31981 gcaaaaccga tcaagctttg gggttctgct agaataatat cgccttccat tgcaaaactg
    32041 gcagttactc ctccggtcgt cgggtccgtt aaaacagtta gataaaaaag accttcattg
    32101 ctatgccgtt tgacagcagc agagattttt gccatctgca ttagagaaaa gattccttct
    32161 tgcatccgtg cgccacctga agctgtgaac aagacgactg gaagactttc ctttgttgct
    32221 cgttcgaata atctggtgat cttttctccg acaatcgttc ccatacttcc catgataaaa
    32281 ttaggatcca tcactccaat aatgaaggga atcccctgaa tggttgcttt accagtgagg
    32341 actgcttcat gaagtcctgt tttatcttgc atttttttaa ttttttccgt atattcggga
    32401 aatgctagcg gatctttggt tacaagatcc gtatcccatt cttcaaaact tttttcatca
    32461 ataatcaaag ctagacgctg ccatgcaccg attcgaaaag cgtatccgca atgagggcat
    32521 actttttctt caccgatgtc tttcgtataa aggatatgtt tgcaatttgg acactttgcc
    32581 cacatgttat caggaacaga tggcgagtta gcaggtttgc tctctctatt aggattgatc
    32641 cgaatatatt tctttttctt aaacagagcc atctatgcgc ctcctatctc cgtttctggt
    32701 gtccaattcg gtaaaaattc ttcttgtaaa aatgctgtgc tgtaatcacc tgctatgact
    32761 gcaggatgac taatcaaatc catctgaaat tctgcgttcg tgatgattcc ttctgtgata
    32821 aattcactta aggctcgctg catcttcatt aatgcttcaa aacgcgtatt tccatggacg
    32881 attatttttg caatcattga atcataatat ggcgggatcg tatatcccgg gtaaactgca
    32941 ctgtctactc gcagtcccat cccacctgct ggaagcagta agttttggat cttccctgga
    33001 gaaggagcaa aatggaaagc aggattttct gcattaatcc ggcattcgat tgcgtgtcct
    33061 tggaatacta cttcttcttg acacacattc aaaggctcac cggctgctat ctccacctgt
    33121 ttttttacta aatcgattcc tgtgaccatt tctgttactg gatgttccac ttggattcga
    33181 gtattcattt ccatgaaata aaaatcgcct tcttcatcca tcagaaactc gatcgttccg
    33241 gcattttcat aattgactgc tttagctgct cgaacagcag cgtctcctag tgcttctctt
    33301 tttgtttgtg agatcactac agaaggagat tcttccagta ctttttgatt gttgcgttgt
    33361 aaagaacaat ctcgctcgcc taaatgaatg acatgaccaa atcgatcacc taagatctga
    33421 acttctatat ggcgagcagg ataaatgatt ttttccaaat acatatcatc atttccaaat
    33481 gccgctgctg cttcttgctg agctgaagaa aaatgctgtg ggagctcttc ttttgattga
    33541 actttccgaa tgcctttccc gccaccacct gcagctgctt tcagcatcac tggataacca
    33601 attctgtctg ctatttccaa tgcttcttct actgtagata atacaccagt acttcctgga
    33661 atgactggga catttgcttc ttgcatcaat tgacgcgcat tgatcttatt tcccattgca
    33721 tcgatcgttg cacttttagg accaataaat gtgatattgc actcttcaca catggaggca
    33781 aatcggctat tttcagataa aaaaccaaat cctggatgaa ttgcttcggc ttttgtcacg
    33841 attgcagcgc tcagtacttc ctgaacattc agatatgaat caacggcttt tgccgggcca
    33901 atgcagattg cttcatctgc taactgtgta tgaagtgctt cggcatctgc ttctgaatat
    33961 atcgctacgg tttggatccc tagttcgcgg catgcacgaa tgatacgtac agcgatttca
    34021 ccgcggttag ctatcaatac tttagaaaac atatttcacc tatccaatca taaaggttaa
    34081 ttccgcttcg gctacttttt taccgtctac tttagcgatt cctttgccta ttccggctga
    34141 agctttcact ttcaatatct caacttcaag gtataaggta tctcccggtg taactttctt
    34201 acggaatttt gctttgtcca atccgccgaa ataagccgtc tttcccttga attgttcaag
    34261 agaaagtaat gcaactgctc ctgcttgagc cattgcttca acaatcaata cccctggcat
    34321 aacaggttct tctggaaaat gtccttgaaa aaagggctca ttgatcgtta catttttctt
    34381 agcaacgatc cgttctcctt caaccatttc ttccactcga tcaatcaaaa gcattggata
    34441 acgatgtgga atgatttctt ttatttcttg tatgttcatt gttttccctc tttcctgctt
    34501 tgcttatttt tgctgaatcc taaagagtgg ctgtccatat tcgacaactg actcgttttc
    34561 tacaaggatt tctgtgatca ctccgtcggc ctcactagtt atctcattca tcagtttcat
    34621 cgcttcaata atgcagataa cttctccttt ggcaacttga tcacctactt ttttgaaagc
    34681 tggtttgtcg ggcgctggtt gcagataaac gattcccacg attggcgaaa caacctcgat
    34741 tccatcaaat actgccgatt ctttttcttt cattatttct ggagcagttg ttgcttgttc
    34801 aggtatgaca ttgactggct ccgaaactgg caacgtttcg tttgtttgaa ccatattcat
    34861 gcctcgactt gttttatttt tattcatata caattcaaat tgaccttcac gcaaatcgaa
    34921 ttccgttagc gaggattgat caaattgact gactaattct ctgatttcat tgatatccaa
    34981 aattattcct cccagcgttt catgcacaga accgcattat gtccgccaaa ccctaatgaa
    35041 ttactcattg cataagtaaa acttgcaggt ttgctttcgt ttttgacaac tgtcaagtca
    35101 atctcaggat cttgtttttc tacattgatc gtaggtggga taaattgatg ttctaatgcc
    35161 agcaaagttg ccaaggcttc gatcccgccg gctgctccca ataaatgtcc agtcatcgat
    35221 ttcgtgctgc tgacgtaagt atctctgaaa ttttcaccta atgcgatttg gattgctttt
    35281 gcttctgcct ggtcattggc tggtgtactt gttccgtgag cattgatata tccgacttgt
    35341 tccggctgta caccagcttc ttccatcgca agcttcattg ctttagatgc accagaacca
    35401 tctggagtag gagctgtcat atggtaagcg tcacagtttg caccgtatcc aacgatttct
    35461 ccatagattt tggcaccgcg agcttgtgca tgttctaaag attcaagaac tagaacgcct
    35521 gctccttcac ccatcacaaa accattccga ttttcgtcaa acggaatcga accacgatta
    35581 ggatcagttg attctgagag tgctgttaaa gctgcaaatc cagcaatccc catctcacaa
    35641 atcgttgctt ctgttcctcc agcaagaatg acatcagaat agccatgttt gatgttacgg
    35701 aatgcttccc caattgaatt cgttccgcta gcacaagctg ttacgatagc tgtacaaata
    35761 ccttttgcac ctacacgcaa agcaatattt ccagctgcca tgttggcaat cgccattggt
    35821 acgaacattg gagaaactcg ttttgcacct ttttcatgta gacgaataac ttggttttcg
    35881 attgttggaa gaccaccgat cccagatccg atgatgacgc caaaccggtc ttgattcatt
    35941 ttttctttat ctaaaccgct catctccatt gcttctaaag cagcgtagat tccatagatc
    36001 gaaaacatat ccattcgttt gctatctttt ttaataaaat atttatcgta agggaaatct
    36061 ttgacttcac ccgctaaggt aatccctgtt tctgaagcat caaatttagt gatcggtgcg
    36121 atgccattcg tcccctcttt taagctattc aaaaagctgt ctgcgtcatt tccaataggt
    36181 gaagtgactc catagccagt aattaccact cgattcattt gtttgctctc cttttcttat
    36241 ccgtgcatga ccaatccgcc atcgacattg atgacttgtc cggtgatata tggattttgt
    36301 gctaagaaaa ctgctgtttg tgcaatatct tctacttgtc cgaaacgctg catcggaatt
    36361 tgcttttccg cttgttcctt gactttgtct gctaaaactt ccgtcatatc agttgtgatg
    36421 aatcctggcg caatggcatt acatgtaatg cctctagttg cagcttctcg tgccacagat
    36481 tttgttaatc ctactacgcc agctttacta gctgcataat ttgcttgacc aatatttcca
    36541 atcaacccag atacactaga gagattaatg atggcccctt ctcgctgctt catcattttt
    36601 ttcaatacgt gctgcgtcat attgaaggtt ccaatcaaat tgatatccag acattttttg
    36661 aaatcttctg catccattcg catcacaagt ttgtcatttg tgattccggc attgtttact
    36721 aacacatgga tcgatccaag cttttcttct gcttctttga tcatttgtcc cgctttctca
    36781 taatcagaga tgtcaccgga aactcctacg cattttacac cgaatgcttc gatttcttct
    36841 atcttttctt ttggaatctc tccgcgacca ttcaaaatga tatttgctcc agcttttgca
    36901 aaagctaagg ccatcgcttt gccgattcct cttgtactac ctgtgataaa tacatttttt
    36961 ccttttacat ccataacgtt cctccttata gtattgctat tgtttcatca aatgtctgct
    37021 tattctcaac acgcagaact ggtattgttt tatcgatttt tttcataaat ccgcttaata
    37081 cttttccggg gccgacttcg atgacttgtt cgatgccgat tgtttttaac ttatggatac
    37141 tctcatagaa acgaacaggt tgcatgactt gctgttcaag tagtcccgcg attgtttctt
    37201 tcttcattat ttccgttgtt gtgttgctta tgataggaaa agaaggttca gagaattgaa
    37261 tctgacttag gtccttcgcc agtttttttg ctgccggttc taaaatagct gtatgaaaag
    37321 gcccgctgac atttagaggg atcattcttt tgaacccttt ttcttttaat agtaaaacag
    37381 cttcgtctac tgctttttct tcgccaccaa tcacgatctg ctgaggtgta ttataatttg
    37441 caggagatac gatgccgtac ttgctagctt catgacagct ttcctcgatc gtttcaatcg
    37501 gcgcattcat cactgcaacc attttcccgc ttccagctgg ggcagcttct gtcatataag
    37561 cgcctctttt tgctactaac gcaactgctt cagtgaagga tagcgcatta ctagctacta
    37621 atgccgaata ttctcctaaa ctcagtccta aagctgcatc tgggatgatt ccatgctcct
    37681 tcaataagcg ataatacgcg atgctgactg ttagaatagc tggctgtgta tattgcgtct
    37741 gatccaaacg ttcattttct gtaaagcaaa gttcagccat atcgtagccg agaatctcac
    37801 ttgcttcatc aaatgtctgc tttacaacgg cttcttcata taaatctttt cccatacctt
    37861 gatattgtgc accttggcca ctaaataaga atgctgtttt catgtttttc tccaatatat
    37921 ccagaatata tgtttgattc ttcctattca aaaaggccga gacattccta tttcaggaaa
    37981 tgtcccagcc cccaacctaa ttttaatgat tatgcagttt gtttttctac gtaagtcact
    38041 aaatcttgaa ccgttttgat tccgtcttct gtttcgattt tcacgtcaaa ttcatcttca
    38101 atttcattga tgatttggaa taaatccaag ctgtcagctt ctaagtcttc ttggatgtca
    38161 gtagtcaatt tgatttcttc agtttctttt cctaattctt ctgcgatgat ttcttgaatt
    38221 ttttcgaata ccataataat atattcctcc gatattgttt gctttttatt tttataattt
    38281 aacagtctac aactccatga gaatacttcc ccatgttaaa cctccgccat agcctgtaaa
    38341 tattactttc tgctgttttc ctaaggtgat ctttccacta gaaactgctt catccaataa
    38401 gatagggatg cttgcagcag atgtattccc atatttatcc atattggtca ggaacttttc
    38461 ttgcggcatc tttacttttc gggcaatttt ctcaataatt ctgaggtttg cctgatgcaa
    38521 aagcagataa tcaactggtt tgtctttcat gacttcttgg atattgtttg caacgtctcg
    38581 tacggcaaaa tcaaaaatat ctctgccagt catttgcaaa taatacgaac cttctgaatc
    38641 ttctgaatag aacggatttt tattttgctg gtagccagcg gtcaatgagc tacttctggt
    38701 accgtcagct gctaattttt ctttcagcaa ttttttctgt ggattcgctt ctaagagaat
    38761 cccacctgct ccatcgccaa acaacacagc agtcgtacga tcagaccaat cgattagctt
    38821 agatagtgtt tcaccaccaa tcaccagtcc cttagttgag ccgcagcgga tcattttttc
    38881 agccatgctt aacgcataaa caaatcctga gcacgcagca ctgatatcaa aagcgatagc
    38941 atgagttgct cccaatttcc cttgtacttg tgctgctaca gatggtgtcg tgtaatcggg
    39001 cgacattgtt gctactaaaa taaaatccaa atctttaggg tttagatttt tctgttttat
    39061 caatttttcc gccactaaaa tgcataaatc agaagtctcc tgatttgtta cacatcttcg
    39121 ttcacgaata cccgtccttg acgaaatcca ttcatcagag gtatccatca tcttggaaag
    39181 atcattatta gtaataatct tttcaggaag gacgctggct gttgcagtaa tcattccaaa
    39241 ttgttccatt aaatatcctc acttatagtc ttgcaagaag tcgtgcaagt ttttcagtgc
    39301 atccagcaag gcatgctgtt cctccgtagc cattccgtct aagatgttct tgaccatttc
    39361 acgatgaaaa tgctgatgga cccgaaatag taactttcct tttttcgtta gtcccaactt
    39421 tacaacgcgg cggtcatctt cactgcggat acgttcgaca tagccttttt ttactaactt
    39481 gttaatagca gtggtcaagg tcccaacagt aattgatagt tctttggcta cttctgaagt
    39541 tgtttttttc ttgtacatcc cgattgcctc gatcgtgtgc atctctgtga ttgacagatc
    39601 tttgaattga gattttttca gctcagactc ttcgattgtc aaaatatcat tgaagacact
    39661 aacaagataa tcatttactg tttttaaatc tggttccatg ttccaccgtc cactaattag
    39721 tttgattatc aaatcttttg atgttcaaac tatatcttaa cttttttcaa aatgcaacct
    39781 taaaagatca tttttttact atatgagctt tttttaagat tttactcatt taaaacaact
    39841 gataaatcag catttataat ttcttttatt agaaaaatca tctatctcac atattttgat
    39901 tatcaaagta ttttctgtga acagaactat agaattccct aaaacttgtc cattatttca
    39961 aaatttgtta tagtcttttt attcaaagcg taaaaggaga tcctatgtta aaagaaaaaa
    40021 tgaaaactct ccccatgctg ccgggtgtct atcttatgaa agaccgagat ggtaaggtca
    40081 tctatgttgg taaagcaaaa cggctcaaaa atagagtaag cagctatttt catcagaata
    40141 aacagcattc aaaaaaagta ttacgtatga ttcatcatat aacagatttt gatttcgtcg
    40201 tagtagacac ggaattagat gctttattgc tcgagtgtca attgatccaa cattaccgtc
    40261 ctttttataa ccgacaaatg aattatttca gtaattataa ttatgtacat attaccaata
    40321 agggatttgt attaacagat actcctacgg ctcgaacata cgggcctttt cgtctctata
    40381 aaaaaatgcc gtctattttg cgtataatgg aagaaactta tcaaatgcct tggttgtctg
    40441 aaattagttt gttagctttg cgagtccagc ttcctgacct acaggaaatg acttttgaac
    40501 agaaaaaaaa ggaactccaa gggctgtttc aaggccgaaa taaaaagcta ctgacttact
    40561 tgaaaaaaag acaacaacat ttcatctatc agttgaattt cgaaaaagcc ggtatgcttc
    40621 aaaaagatat cgaattagtt acttatttta ttagacggat ccaggaacaa aagcagtttt
    40681 taagaacacc atcgctcacc ttcagcatgc cattagcagc agatgagagt cagaaaaagc
    40741 actacctcgt ttgttatggt caacttgcag aaacaatgat tacctctggt gacgtttctc
    40801 ctgacttcta ttatgaaaag aaagaagctc atttatcttt gaaacgtcaa ttgtcaaaag
    40861 aagaaatcga tcctgtacaa atcttgatca gttaccgcaa aaaattagaa aaagaacagt
    40921 ttgaaattga actgttaaac aaaaaagaag ctgaaaagca actaaattag ttgcttctcg
    40981 gcttctttta ggcatcttca acttcaaatg tcaattatcc taaaatttat tggattaagt
    41041 catagatttc catcgctacg atatcgatat tatcaaattc gtattgctga tgagtatctg
    41101 tttcagttaa ttcaaatgta tcggtcgctt tatcataagt tactgtacac ttctctacgc
    41161 cttctttttc aaaacggcga acttgcagtt cattatctgc tgactcgacc atagcctcca
    41221 gtcgttttat gattgcgact aattgtgaat gtgtcatcgg aggtcctcct tttcttattt
    41281 ctgttatatt gtatcaaaag catagcctac ttgcattgat tttctctaaa aaaactcgtt
    41341 ttttatgatt ttttttctgg tatttttcct tcaggccacc aaagtttgat caaagcttgg
    41401 gttccgtcat tctcaaaacc tttatctgcc aactcttcat atagtttcaa tgcttgggta
    41461 gttgctggca atacaagatc cattttttct gcttcttcta atgcaatctt taaatctttg
    41521 ataaaatgtt tgacaaaaaa accaggtgtg taatcttctt ttaaaatacg aggagaataa
    41581 ttgcttaaag accagttagc tgcacttcca cctgaaagcg tctcaatcac tttctttaaa
    41641 tcaagtccgt ttttttgtgc atagacaagc atttccgtca ttcctgtcat cgtacctgca
    41701 atcatgatct gattagccat ttttgtatgc tgacctttcc cagcagaacc atgcaatgta
    41761 aatgtcgtac caaattcttt gaataaaggc agtacttgat cataaacggc ttcttctcca
    41821 ccgaccatga tcgtcagtgt accattcttt gctcctaagt caccaccgga taccggtgca
    41881 tctaacgcat ctgcgccttt ttcttttgct gtttttgcaa ttttttctgc caggcttggt
    41941 gtacttgtag tcaaatcaac taaaatatgt cctgagatat ctgcagaaaa aatccccgac
    42001 tgtccatagt agatttcttc tacatctttg gggtaaccta ccattgtaaa gagaatatta
    42061 ctttgttctg ctaccgcttt tggtgtatct gcccagatag ctccttctgt tactaaagga
    42121 tcagcttttg cttttgtccg attatagaca gctacttcgt gtcctgcttc tagtagatgg
    42181 cgtgcgacag cacttcccat gacgcctgtt ccgataaaac caagtttcat tttttcgacc
    42241 tcctaaaaat caaaaatcct tgcttctatg ctagtatacg ctagaaacaa ggattttttc
    42301 ataaaaaatg tttgaatttt atcttttaaa tgaatttaat tttattttga ttcgttcaat
    42361 cgagtcttct tcttcttttc ttcgcatctc ttcttcatga taaacaacca tgtcttgata
    42421 aaattcgatc atagcttcgc cgaaatgtgt agatgaaata tcataaagtt tagcttctaa
    42481 aacttttgga tctttaggaa cttcactgga aatataatca ataagtgctg gtgcaaagtc
    42541 ttcgtcggtt tcaaaagttt tccctaatga aggatgatcg aacaatcggt tcaaataagc
    42601 atttccttcc acgacacaag gtgttccggc tgccatcgct tctgtataag taagcccttg
    42661 tgtttctgaa gtagaagcac tgacaaaata atctgccgct ttataataaa gtgctacatc
    42721 attgttgtcc acttctcctg tgaactgcac aaattcttct aactgcagtt ctgagatcaa
    42781 ttcctctaac tcttctacat aaggtccttt tcctacgata actaatctgg cgttaggata
    42841 agcggagatg acctgaggaa acccattaat caaggcttgg atatttttct cataagaaat
    42901 cctgcttaaa gaaagaatca tcaaatggtt ttcctgaaga cctagtgact cccttaattt
    42961 gctgatatcc tgctgagtga tatcagaacg tttgaatttt tcaatgtcga taccagtagg
    43021 aatcacgcga agcggtgcta ttacaccata gctgcgtaat gtatcaataa cacgttcact
    43081 tggacaaact acacctgtcg tatgatttgc aaataatcta gacaagtatt ttacatggga
    43141 ttgcctgatc acttttcctt taccgatata atgaaggtag tcttcataca tcgtatggta
    43201 agtatggatc agaggtattt tcaacttctt agctaccatc ttcccaagta tccctgctcc
    43261 gaattctgta tgggtatgaa taagatctag ttctagttct ttggcaacca aataagcata
    43321 ccacatgcct ctaacaacaa ctcttcgatc cttgaaagaa ataaatggta cacttggcat
    43381 tcgaatcaca tctttttcca acttatccgc attaggatcg gtcgttgtaa aaatatagac
    43441 ttcatgccca tgtctttcta attcttgttt taatgttttg atcgatgtag caactccgct
    43501 gacttgcgga aagtaggtat cggtaaaaaa gccgattttc atgtttttcg cctccaaact
    43561 agtccttgac ctgatttact ttttttaatt tgctagagac tttttcattc agtacacttt
    43621 cgtatacatt tttaagttct tcaccgattt tattgatact tcgctctttt gctgtttgat
    43681 aaccggcttg tgtcgtactc ggtagttctt gattggtaat ctgttggatc agtcggataa
    43741 attcttcgtt tgtcttcccc atatagcagt tcttgctatc ttctaaccag ccattataca
    43801 ctggaatatc tcgaacaagt acgttttgtt tgcttgctaa agcttctaaa acaacgatcc
    43861 cttctgtctc ttcataagaa gggaaaaaga atagatctgc acctgaatac gcaccttcta
    43921 tgatctctcc acgaatgtaa ccaggaaaca ggacattttc aggatgatct tcttttacaa
    43981 ttttccggat gttccgagga atcgagtaca tgggaacatg accaaaccaa ataaatgtgt
    44041 attcgggcat cttcttagca atttctacga aatcaatgat tcctttacgt tcgaaaaaca
    44101 aaccgacaca aatgattact ttttgatccg gagacagttt gaaatattct ctgaactttt
    44161 gttctttcat tggatcaggg tgatatttct ctaagtcgat cccattggaa atagcttgaa
    44221 tcggcacacg gataccatag ctttccaaca actgttttga ataaggtgtt ggcgtgatca
    44281 gatagtccgc tttttggtac aatcctacca gatatttttt tacgatagga gaaagctggt
    44341 tcgatccgat aaaggaattt cggaaatctt cctctgtaga atgcgcatga tagacaactt
    44401 tttttccttc tcttctggct ttattgacca tattatgact attgattccg tatgtattga
    44461 tgtgcaggat gtcataatct tctttttcat ctagtgtata agagataccg acttccgtca
    44521 gagcacgttt ttgatgatca agcgcacgcc cgattccaga ttttgcaagc atcttttcac
    44581 tttcaaaata taataatacc ttcaccttac gtcccccttc acttatatag tataacatag
    44641 cctacaaact gtcactcaaa cttaagccct atttttgtct attcttactg acaaaaacgt
    44701 tttcttaaaa aagaaca
//
LOCUS       DARPZJ010000019        42900 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.019, whole genome shotgun sequence.
ACCESSION   DARPZJ010000019 DARPZJ010000000
VERSION     DARPZJ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.019"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            6..305
                     /locus_tag="SLE23_001278"
     CDS             6..305
                     /locus_tag="SLE23_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8468195.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="SLE23_001279"
     CDS             378..1739
                     /locus_tag="SLE23_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEI8468196.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="SLE23_001280"
     CDS             1761..2021
                     /locus_tag="SLE23_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468197.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="SLE23_001281"
     CDS             2035..2787
                     /locus_tag="SLE23_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEI8468198.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="SLE23_001282"
     CDS             complement(2881..3486)
                     /locus_tag="SLE23_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8468199.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="SLE23_001283"
     CDS             complement(3539..4513)
                     /locus_tag="SLE23_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HEI8468200.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="SLE23_001284"
     CDS             complement(4891..5610)
                     /locus_tag="SLE23_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8468201.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="SLE23_001285"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="SLE23_001285"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEI8468202.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="SLE23_001286"
     CDS             7161..8558
                     /locus_tag="SLE23_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8468203.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="SLE23_001287"
     CDS             8639..9079
                     /locus_tag="SLE23_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8468204.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="SLE23_001288"
     CDS             9227..9553
                     /locus_tag="SLE23_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8468205.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="SLE23_001289"
     CDS             9554..10303
                     /locus_tag="SLE23_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468206.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="SLE23_001290"
     CDS             complement(10383..10838)
                     /locus_tag="SLE23_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEI8468207.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="SLE23_001291"
     CDS             complement(11265..11540)
                     /locus_tag="SLE23_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468208.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="SLE23_001292"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="SLE23_001292"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEI8468209.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="SLE23_001293"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="SLE23_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEI8468210.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="SLE23_001294"
     CDS             14770..17436
                     /locus_tag="SLE23_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8468211.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="SLE23_001295"
     CDS             17800..18552
                     /locus_tag="SLE23_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8468212.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="SLE23_001296"
     CDS             complement(18574..19728)
                     /locus_tag="SLE23_001296"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEI8468213.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="SLE23_001297"
     CDS             19913..22354
                     /locus_tag="SLE23_001297"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEI8468214.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="SLE23_001298"
     CDS             complement(22684..23388)
                     /locus_tag="SLE23_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468215.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="SLE23_001299"
     CDS             complement(23575..23820)
                     /locus_tag="SLE23_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468216.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="SLE23_001300"
     CDS             complement(23837..24688)
                     /locus_tag="SLE23_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEI8468217.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="SLE23_001301"
     CDS             24854..25858
                     /locus_tag="SLE23_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEI8468218.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="SLE23_001302"
     CDS             complement(26099..26455)
                     /locus_tag="SLE23_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8468219.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="SLE23_001303"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="SLE23_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEI8468220.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="SLE23_001304"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="SLE23_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEI8468221.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="SLE23_001305"
     CDS             complement(30815..31576)
                     /locus_tag="SLE23_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8468222.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31854..32375
                     /locus_tag="SLE23_001306"
     CDS             31854..32375
                     /locus_tag="SLE23_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEI8468223.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="SLE23_001307"
     CDS             32434..33294
                     /locus_tag="SLE23_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEI8468224.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="SLE23_001308"
     CDS             33479..35794
                     /locus_tag="SLE23_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8468225.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="SLE23_001309"
     CDS             35976..37817
                     /locus_tag="SLE23_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEI8468226.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="SLE23_001310"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="SLE23_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEI8468227.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39170..41269
                     /locus_tag="SLE23_001311"
     CDS             39170..41269
                     /locus_tag="SLE23_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEI8468228.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41465..42328
                     /locus_tag="SLE23_001312"
     CDS             41465..42328
                     /locus_tag="SLE23_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEI8468229.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42433..>42900
                     /locus_tag="SLE23_001313"
     CDS             42433..>42900
                     /locus_tag="SLE23_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEI8468230.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRALC"
BASE COUNT        14099 a         7513 c         8872 g        12416 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttatgaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt atagaatatg
    39121 atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga tgaaaaaatg
    39181 tccaaattgc ggatcgaaaa aaatggagca gaatactatc tgtccagact gcggtcatca
    39241 aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata cagatgcagc
    39301 tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa acgatccaat
    39361 cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat tcgaaaaagc
    39421 agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag agaaaaatga
    39481 acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc aagaagaaac
    39541 gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg ataatgagga
    39601 agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa aagaagagca
    39661 cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca aagtagagcc
    39721 agaaaaggaa caagaaactg aaaaagactc tgatagagaa aacgccacag gtaaagaaac
    39781 agtaaaaata aaagacgtaa aaacggatat cacagaaaaa actgaagtat ttactgaaaa
    39841 acaattagaa aaggaaaaaa cgaataaact gccggaagca gagaaaaaag aaatactcga
    39901 aaacacagac aaaaagtcaa cagagcccga tgaaataaat agtgaatccg atgctgaaaa
    39961 tcaatctgta agcaaagagg gtactgatct tgaagcaaaa atagaaaaag aagagaacca
    40021 gcctaagctg tttgaagcag aagcgaaatc aataacaatc gtgccagata ctgaaaaaac
    40081 acatcaagaa tcaaacttag aaaaaacaga tccagataaa gcgcaaaaga aaaaatcaaa
    40141 aaaagtacct tatctcgttt tagcagcagt acttctactc ggtggaggaa gctgggctta
    40201 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    40261 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    40321 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    40381 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    40441 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    40501 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    40561 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    40621 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    40681 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    40741 tgctcagttg aatgaacaat tgaaacaagt agataagatg ctcactgata aagagaaaaa
    40801 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagctgaag aacaagcaaa
    40861 acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg tcgcacaagc
    40921 agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga atcagccaat
    40981 caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga cgtgggcacc
    41041 aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg ttgaaggagg
    41101 ttacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattataatc tatatgccac
    41161 ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat tttacatcgt
    41221 aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat tttaggcaaa
    41281 tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaagggg agtatgacac
    41341 aactgttgtc atactccttt tttcaccttt ccaaaccaag gctcagctat tcaagtagat
    41401 aacattatgt tatgatagca aagaaatgta ttaagaaaac ctttcactat agagggagaa
    41461 aaaaatgaac gatttattag caactatatt tacaggtatt attattgatg aaaatgaaaa
    41521 aaactacttt gtccaaaaaa acggacaaac ctttggctta agcaaatcag aaggtgaaca
    41581 caaaatcggt gaagcagttg aaggattcgg ttaccaaaat caaaaacatg aaaatcggat
    41641 cactacacaa attcctaaaa gccgtatcgg tcattacgct tttggaatcg ttactgctac
    41701 acgaaaagat ttaggtgcgt ttgtcgatat cggtcttcca gataaagact ttgtcgtatc
    41761 tcttgatgaa ttgccgacaa tgacagagct atggcctaaa aaaggggatc gcttgatgat
    41821 ttcccttaga gttgatgcaa aagaccgtat ttggggcagt ttagcagatg aaaaaatatt
    41881 caaatcttta agcaaatatg gaacagaaga aatgaaaaac aaagatgtga taggaacagc
    41941 ataccgcttg aaattaacag gtacgtacgt tttaacggaa gatttctatc ttgggtttat
    42001 ccatccttct gaacgatata atgaacctcg tctaggcgag cagataaaag gtcgagtgat
    42061 tggtgtccga ccagacggtg tactgaatct ttcattgaag ccaagagcat atgaagctat
    42121 atcagatgat gcacaaatga ttttaaccat tttagaacgt tctgcagatc agcaaatcaa
    42181 ctttacagat aaatcggatc cagaagaaat catgaaagct tttggtatca gcaaaggagc
    42241 atttaagcgc gcattaggta atcttttgaa acaaggattg attacacaag aaaacggtgt
    42301 gacaaaacta gtcaaaaaat ctaattgaga atcccttgca tgtttttctt aactagctta
    42361 taataatttt aattaacata gtgttatatc tttttttatt tgtaattatt ataaattgtt
    42421 ggggttgagt aaatggtcat gaatgctatt tcggcgatga aaaaaacaaa acagcagcta
    42481 catgaagcgg ggtttaagct gacaccgcaa agagaagcta ctctgcttgt gcttttggaa
    42541 aatgagaaag agcatttatc tgcagaagaa atcttctttt tagtgaaaaa aaagagtccg
    42601 gaaattggac ttgctactgt ttatcgaacc cttgaaatct tgacagaatt gaaaattgtc
    42661 gataaagtaa gttttaatga tggattagcc cgttatgatt tgagaaaaga aggcgccaaa
    42721 catttccatc atcatttact atgcttgaac tgcggcacga tcgaggaagt agaagaggat
    42781 cttttacttg aagtggagca agtagtagaa gaacgttatc attttttagt aaaagatcat
    42841 cggctaacgt tccatggaat ctgtcaggaa tgctatgaaa aagaaaaaag ggctctttgt
//
LOCUS       DARPZJ010000020        41153 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.020, whole genome shotgun sequence.
ACCESSION   DARPZJ010000020 DARPZJ010000000
VERSION     DARPZJ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.020"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            239..481
                     /locus_tag="SLE23_001314"
     CDS             239..481
                     /locus_tag="SLE23_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HEI8468231.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            478..948
                     /locus_tag="SLE23_001315"
     CDS             478..948
                     /locus_tag="SLE23_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEI8468232.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            1076..2290
                     /locus_tag="SLE23_001316"
     CDS             1076..2290
                     /locus_tag="SLE23_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEI8468233.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            3279..3488
                     /locus_tag="SLE23_001317"
     CDS             3279..3488
                     /locus_tag="SLE23_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HEI8468234.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3600..5213
                     /locus_tag="SLE23_001318"
     CDS             3600..5213
                     /locus_tag="SLE23_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8468235.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5248..6459
                     /locus_tag="SLE23_001319"
                     /pseudo
     CDS             5248..6459
                     /locus_tag="SLE23_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6482..7408
                     /gene="glsA"
                     /locus_tag="SLE23_001320"
     CDS             6482..7408
                     /gene="glsA"
                     /locus_tag="SLE23_001320"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HEI8468236.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7616..9076
                     /locus_tag="SLE23_001321"
     CDS             7616..9076
                     /locus_tag="SLE23_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468237.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9297..11060
                     /locus_tag="SLE23_001322"
     CDS             9297..11060
                     /locus_tag="SLE23_001322"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HEI8468238.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11144..11602
                     /locus_tag="SLE23_001323"
     CDS             11144..11602
                     /locus_tag="SLE23_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEI8468239.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11711..12394
                     /locus_tag="SLE23_001324"
     CDS             11711..12394
                     /locus_tag="SLE23_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEI8468240.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12541..13155
                     /locus_tag="SLE23_001325"
     CDS             12541..13155
                     /locus_tag="SLE23_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEI8468241.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            13171..13377
                     /locus_tag="SLE23_001326"
     CDS             13171..13377
                     /locus_tag="SLE23_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468242.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13918..15048
                     /locus_tag="SLE23_001327"
     CDS             13918..15048
                     /locus_tag="SLE23_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEI8468243.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            15140..15895
                     /locus_tag="SLE23_001328"
     CDS             15140..15895
                     /locus_tag="SLE23_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8468244.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15953..17992
                     /locus_tag="SLE23_001329"
     CDS             15953..17992
                     /locus_tag="SLE23_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HEI8468245.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(18101..19252)
                     /locus_tag="SLE23_001330"
     CDS             complement(18101..19252)
                     /locus_tag="SLE23_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEI8468246.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(19406..19936)
                     /locus_tag="SLE23_001331"
     CDS             complement(19406..19936)
                     /locus_tag="SLE23_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEI8468247.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(20035..20385)
                     /locus_tag="SLE23_001332"
     CDS             complement(20035..20385)
                     /locus_tag="SLE23_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEI8468248.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(20542..22071)
                     /gene="ahpF"
                     /locus_tag="SLE23_001333"
     CDS             complement(20542..22071)
                     /gene="ahpF"
                     /locus_tag="SLE23_001333"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEI8468249.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(22081..22644)
                     /gene="ahpC"
                     /locus_tag="SLE23_001334"
     CDS             complement(22081..22644)
                     /gene="ahpC"
                     /locus_tag="SLE23_001334"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEI8468250.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(22788..23450)
                     /locus_tag="SLE23_001335"
     CDS             complement(22788..23450)
                     /locus_tag="SLE23_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8468251.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            23634..25280
                     /locus_tag="SLE23_001336"
     CDS             23634..25280
                     /locus_tag="SLE23_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEI8468252.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            25271..26353
                     /gene="uxuA"
                     /locus_tag="SLE23_001337"
     CDS             25271..26353
                     /gene="uxuA"
                     /locus_tag="SLE23_001337"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEI8468253.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(26461..28014)
                     /locus_tag="SLE23_001338"
                     /pseudo
     CDS             complement(26461..28014)
                     /locus_tag="SLE23_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            28162..29303
                     /locus_tag="SLE23_001339"
                     /pseudo
     CDS             28162..29303
                     /locus_tag="SLE23_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(29429..30508)
                     /locus_tag="SLE23_001340"
     CDS             complement(29429..30508)
                     /locus_tag="SLE23_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8468254.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(30611..31051)
                     /locus_tag="SLE23_001341"
     CDS             complement(30611..31051)
                     /locus_tag="SLE23_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8468255.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(31108..31518)
                     /locus_tag="SLE23_001342"
     CDS             complement(31108..31518)
                     /locus_tag="SLE23_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEI8468256.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(31698..32132)
                     /locus_tag="SLE23_001343"
     CDS             complement(31698..32132)
                     /locus_tag="SLE23_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8468257.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(32232..33080)
                     /locus_tag="SLE23_001344"
     CDS             complement(32232..33080)
                     /locus_tag="SLE23_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8468258.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            33469..35235
                     /locus_tag="SLE23_001345"
     CDS             33469..35235
                     /locus_tag="SLE23_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEI8468259.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            35337..36596
                     /locus_tag="SLE23_001346"
     CDS             35337..36596
                     /locus_tag="SLE23_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8468260.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            36743..38044
                     /locus_tag="SLE23_001347"
     CDS             36743..38044
                     /locus_tag="SLE23_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8468261.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            38047..38898
                     /locus_tag="SLE23_001348"
     CDS             38047..38898
                     /locus_tag="SLE23_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8468262.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            38911..39726
                     /locus_tag="SLE23_001349"
     CDS             38911..39726
                     /locus_tag="SLE23_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HEI8468263.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            39877..41043
                     /locus_tag="SLE23_001350"
     CDS             39877..41043
                     /locus_tag="SLE23_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8468264.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT        13972 a         7121 c         7991 g        12069 t
ORIGIN      
        1 aaaataagaa attgattgtc gttttctttt gcagaaattt aagtgcaggc aattatggta
       61 gttgtcgtaa ttgctgtcag ctcagtgttt atcactgatg gtgtgaaaga tttacggttg
      121 gagatgttca ataagattat tggtgcttaa ttatttttat tgtagtgctg atatgagaat
      181 gttataattg gggtataaaa catacaaata aatttgctga aaaatgaggt atcaaaatat
      241 ggaaaatgaa ttactggaaa acttaggaag acttcacaca actgaacttg gcgttattag
      301 aattaaaaag aacttatctt tgaatgtaga aaatgtaatt gaatggtgca aagaaaaaat
      361 tagcctttct aatgcggaaa tcacaagaaa aggaaaaaac tggtatataa cgattgataa
      421 ttgtattata acggtaaatg cgtacagtta taccgttatc actgctcaca aggtaaaatg
      481 ataaattttt ctataaagga attaaacgca tttgcagtta ttgggcagga agtagaactg
      541 actaattatc aaaaaaagaa tattcagatt agtacacagt tttggagaaa gtttaacagt
      601 agtttgaaaa aagcgtatct ttcacaatca ggaaattggg taaaatatgc ttttatggaa
      661 agaagaaatg gaaaacttta ttatttctgt tctattcccc aaagaaccat taccccagag
      721 ggctttctgt ataaagaaat accgtcttat aaatatttgg ttgtggagca tattggtgct
      781 atggataaaa tatatgaaac ttatggcaag atttatgaag aaattattcc tagtacatcg
      841 tatattccta taaaagatat tatcctacac tttgaaaaat acgattatcg ttttcattgg
      901 aatagtgata attcagttat tgaaatttgg atacctattc aagattagaa gcaattttat
      961 atccatacac acaaagcagt tagtcttagg attgactgct ttttctatac agatttttaa
     1021 tgacaggcaa ttatcaatta tggtagttgc cttttttgat tggaggaatt gaagaatgaa
     1081 tgataaaaac tttattgaag aactaagaca aaagcgtgag gaatacggag taacacaaac
     1141 aaggcttgct gttgcctgtg gtatcagccg tgaatattac aaccgcattg aaaaaggaaa
     1201 acagccattg aatgacgaat taagagaaat catagaaaaa cagattgagc gtttcaatcc
     1261 gcaagaacca ctattcttat tgattgatta ctttcgtgtc cgctttccta ctacggacgc
     1321 attggcgatt atccgtgatg tattacaact gaaatctaat tacatgcttt atgaagatta
     1381 tggaaaatac ggatatgaaa gcaaatatgt acttggcgac atcaatatca tgtgttccat
     1441 gcaggagcat ttaggtgttt tattggaact gaaaggcaaa ggctgtcggc aaatggaatg
     1501 ttatctgctg gcacaggaac gctcatggta tgacttcatg ctggattgta tgacggctgg
     1561 tggtgtgatg aaacggcttg atttggctat caatgataaa gcaggaatat tggatattcc
     1621 aaagttaaag gaaaaataca aggctggcga atgtatgtcc tacttccgta tgcagaaaga
     1681 ttacagcggt acagaaaaat gcggtagcga tttaccaaag aatacaggag aaaccttata
     1741 tctcggttca acaagtagcg aattatatat gtgtgcttat cagaaaaatt atgagcagta
     1801 tgtcaagaat ggcacagaaa ttgaagatac ggagattaag aaccgttttg aaatacgcat
     1861 gaagaacgaa cgagcctatt atgcggttgt agatttactg acctatcggg acgctgaacg
     1921 caccgctttt tctatcatca atcattatgt ccgctttgtt gacagagagg acgacaagcc
     1981 aaaaagtcaa tggataacaa atgatgattg ggcatggttt gtaggggaaa acagagagcc
     2041 gatacgctta accacaaagc cagagcctta cactttacaa aaagcgttgc attggctaca
     2101 aagacaagtc gcaccaacca taaaaatggt acaggcatta gacagagaaa atcgtacaac
     2161 gatactgaaa gatatgattg agcaggcaga actaaaagac aagcataaac atttattaca
     2221 attagagaaa tcaaccatag aagaacgtat agataccgct gttccacaag agaatgacgg
     2281 tattttttaa tgtaattgaa aaatttcaga tttagtcagc aaagagctgt tttcattccc
     2341 tatgtgaagt gaaagaagaa aaataaattt tttattaaat ctgcaacaaa atggctactt
     2401 gcgtacagat atggtgcgag aaaaggaaat ctaaactttt tttgaaaata ggtcattaaa
     2461 tcggggcttg ctgtccctat atgaagtgaa agaagaaaaa agttttgaaa aaatgacgga
     2521 aattcgtgat tagtggacag tcttctgtga aaagaggaaa aacatcatca ttttgtattc
     2581 aaacaggcat tagcagttga gtgttgatgt gaaaagatga aaatactttg ttctcaactt
     2641 aacaatttaa ggtttccgtt ccctatatgg tgcaaagaaa atatttcatt ctattgttgg
     2701 cagtaacggt atggtttggg tagttagggt gtgaaaagga aaatattctt ttttcatcat
     2761 caacttagca aaatgacatt ttctatccct atatggtgca tgaaaagaag ttaaaatttt
     2821 tccatttaaa cttagcaaat ggacgtttgc tgtacagata gtagtgaaaa aggagaaaat
     2881 caaccgttga ttgccaaaat gaaccgttcc atttgtacta ataatggaaa aagttttgga
     2941 ttttggttac gtttctcctc ttttccaacg cgatatatag gaaagacgat ttttttcttt
     3001 caatcgttct ttgacaactg aataaagcta ttcaatacgt ttgacagaca gctagccgtt
     3061 gaaacaaata cgccacgacc tttcccctgc aagagcgagc gaaaacctat ttgtgttctt
     3121 gtaaaagatt tgtcctcttt tatcgccatg acctgtactg tcagataatg atactcccgt
     3181 acagccacag cttgagcatt aagagcgtcg cacgcaatgg gtacggctac ataagaacta
     3241 tgcagaggtg gaactcctgt gggctatgac aaaagccgtt gaattgctta gaaagatttt
     3301 acagaaaggg ggtatgtgtt attgataatg ctgtaaaaac aattcaaaag aaaaatggca
     3361 agtgtggcat tggcaacaga ggaaagacaa agattgtagt aaaagagcat ttttccgaaa
     3421 agggcaaaac aatggaagaa cttctaactg atgtcatgct ggaaaaagca aagcagacaa
     3481 tcgcataaaa tcggtgcagt tgtaagaaat agattgaatg acaaaaagta cccgtgttat
     3541 actttacttg caagcaggta ttgtaaacac gggttagtta taaaggagga taactgacaa
     3601 tgaaacaaca gatttacaat actgcacttt atcttaggtt aagccgagat gatgaattac
     3661 agggcgaaag ttccagcatt accacacaga gaagtatgtt gcgtttatat gcaaaagaac
     3721 atcatttgaa tgtcattgat gaatatattg atgacggctg gtcgggaaca aattttgaca
     3781 gaccgagttt tcaaagaatg attgaggata tagaggcagg aaaaatcaac tgtgttgtaa
     3841 cgaaagacct ttcccgtctt ggcagaaatt atattatgac aggacaatat acagaattgt
     3901 atttccctag tcataatgtc cgctacatag cgattgatga cggtgtagac agcgaaaaag
     3961 gcgaaagtga gattgcacca tttaagaaca tcatcaatga atgggtggca agagatacaa
     4021 gccgtaaagt caaatcagca tttaagacaa agtttgcgga gggggctcat tacggtgctt
     4081 atgctccgtt aggatataag aaacaccctg acatcaaagg aaaactgttg gttgatgatg
     4141 aaacaaaatg gattattgaa aaaatctttt ccctagccta tcaaggttac ggaagtgcaa
     4201 aaatcacaaa gcagttaaga gcagaaaaag ttccgacagc gtcatggcta aattttacaa
     4261 gatacggtac ttttgcacat atctttgagg gaaaacccga aagtaagcgt tatgagtgga
     4321 cgattgctca tgtcaaggcg atattgaaaa gtgaggttta tatcggaaac agtgttcaca
     4381 atatgcagtc tacggtatcg ttcaagagca aaaagaaagt gcgtaagccc gaaagtgaat
     4441 ggtttcgagt agaaaacact cacgagccga ttattgacaa ggaagtgttc tatcgtgtgc
     4501 aggagcagat aaaatcaaga cgcagacaga caaaggaaaa ggcaacgccg atttttgcag
     4561 ggcttgtcaa gtgtgcggat tgtggttggt ctatgagatt tggaacgaat aagacaaata
     4621 aaacgcctta cagttattat gcttgcagtt actacgggca gtttggcaaa ggtaattgtt
     4681 ctatgcacta cattcgttat gatgtgctgt atcaagccgt attggaacgc ttgcagtatt
     4741 gggctaaggc agtacagcag gacgaagaaa aggtattgaa caagatacag aaagctggca
     4801 atgcagagag aatacgggaa aagaagaaaa aggcaagtac attgaagaaa gccgagaaca
     4861 gacaaaatga gattgaccgt ttatttgcga aaatgtatga agatagagcc tgtgagaaga
     4921 taacagagcg aaattttgtg atgttgtcca gcaagtacca aaaagaacag atagaactgg
     4981 aacagcagat aacaagccta agagaagaac taagtaaaat ggaacaggat atgataggtg
     5041 ctgaaaagtg gattgagtta atcaaggaat attccgtacc aaaggaactg acagcaccat
     5101 tattaaatgc catgatagaa aaaatcctca tacatgaagc aacaacgaat gaggataacg
     5161 aaagaataca ggaaattgag atatattacc gatttattgg aagagttgag taatcaacaa
     5221 gagtaatatt tttaactaag ggaaaccggc ggtgtctata cttgggtcag tcgcacattg
     5281 ggaaaacgat tcggttttgc cgcaatcttt ttccaatggt ttgagataac agttggctac
     5341 ttgaccatgc tgtatttctt aactggtgca ttatcctatg caacgggtat tggtgctata
     5401 caaaacaata aatatctgaa attggcaatc ctattgatta ttttctgggc tattttactc
     5461 tcacagttaa aaggaaccaa atacacttca ttgattgctc ggatcggttt tgtagctggt
     5521 atcttgttgc cagcattagt cttgtttggc ttagggatcc attatgtcgc ttcaggcgct
     5581 ccactacaaa cgatactgtc tatgaaaaca ttgattcctg atttttcgaa attgcctacg
     5641 ctggttgttt ttgtttcctt tattttagca tatatgggcg tagaaacatc tgccagtcat
     5701 gcaaatgaaa tggaaaaccc taaaaaggat tatccattag caatgtttgt attggttatt
     5761 ctggcaatca ttttagatac ttttggcgga ttgaccgtcg ctactacagt acctcaacat
     5821 ggtttgtctc ttaatacagg ggtgattcaa tcgttagaat tcctattaag acacattgat
     5881 ccaaatcttg catggattgc gaaaattctt gcgattcttg tttgtttagg tgtcatcgga
     5941 gaaattgctt cttgggtaac ctctccttca aaagcacttc acgtagcagc agaagaagga
     6001 ttacttcctg aatattttgc aaaagaaaac acacacggtg ttcctgctca tttgatgatc
     6061 gcaaatggga tcgttgcaac aatctgggca gccgtcttta cattaagcgg cggggggaat
     6121 aatctttcat ttcttgcagc gatgtcattg actgttgtaa tctacctgat gttgtacttt
     6181 atgtttttcg cgggctattt gaagctggtt tttaaagatg acagtcttga aagagcctat
     6241 caggttccag gcggaaaagt tgtaaaagta atcgttgctt gtttaggtct tttgacttca
     6301 ctttttgctt tttgtatctc atttgttcca cctgctagta tcgcagctgg acagcatggg
     6361 atttatgaaa cgattctgat tgtttcttat cttatcgtct tagttattcc atttacgatc
     6421 tacgcatgcc gtcataaatt ccagcatgca gaaaaataaa aaatgaaagc tggttattca
     6481 aatggaagta aaagaattag aacaattgat tggaaaaaat ttccactatt atcaaacagg
     6541 acaagtggcg gattacattc cagcattagc tgaagtggat cccaaacaat taggtatggc
     6601 gatttatgat ttggatacaa aacaactgat tgagggagga gacgccgatg tgcgctttgc
     6661 catcgaaagc atgtcaaaag ttcccgtatt gttattagca atcaaagaca acggaataga
     6721 aaaagtcttt caaacaatca acacggaacc aaccggtttt gccttcaatt ctatcatgaa
     6781 tatggaaatc aatcatcgca aacatccaat gaatcctttt gttaatgcag gagcgattgc
     6841 aacaacctcg ttgattgccg gtaaagatgc agatgaaaaa tttgagcgaa tcttgtcatt
     6901 tatgaaagag atctgtgatg atcctaatat cacattgaat gaagaaatct atcattctga
     6961 atcaagaaca ggtgatatca atcgctctct tgcttactat atgaaaggta atcaaatgat
     7021 cgaaggagac gtaccggaga tactcgatgc ttatttcaga caatgctccc tcaatgtcac
     7081 cgctacaggc atagcaaaat tagctgctgt gctggcaaat aaaggaattg ctccttggaa
     7141 tggcaaacaa atcattactg aagaaagtgc tacaatcgtc aaatcaatta tgacaactgc
     7201 tggtttgtat gatgaatcag gagagttttc cgtccatgtt ggtgtacctg caaaaagcgg
     7261 tgtaggcggc gggttgatgg cagctgtgcc aaatcgttac ggcataggtg tcttcagccc
     7321 ggcactagat ccatttggta acagcgcagc tggtatccaa ttgttgaaag atgtagtcaa
     7381 agaactagac gctgacatct ttgaataacc attcttgaaa gaggctgggg taaaagtcca
     7441 aacggctcaa agctacctac aatgaggctg aaattgtgag cttgtttgac ttttgtccca
     7501 gtttcttttt ttattggttt ttgaaagggc ttttctaaat aaaaaggaaa caaaaatacg
     7561 atttacagat atgattaaat aaaatcataa gaaaaactgg aggcgtgtat caggaatgct
     7621 ggaaaattac atcgagcgaa atatatttag aaaagtgtat ctgtgtgaac aattatttga
     7681 attccaagaa atagacatcg aacaaacagc tatttctcta agggtgacta caccaacgat
     7741 ccttcacgat ctagaaagtc tagccgagtg tctagaatat tgtataaaag aacaagtaag
     7801 agagaagcat aagtataaac tcgtattcaa acatggtatt gctctttctg agctcacaca
     7861 gtttctgtac ggtcaatctt attttttaaa gtttttaagt tattatttta atggtatatt
     7921 cacgagtaca gaactggctg atcttgaatt tatttctttg agtaaagtat atacaatcaa
     7981 aaaaatcgta ttggattttt ttaaagaaaa tgattatttg aaaaataaag aaatcattat
     8041 cccagaattt gactcgcgga acatcttgct agctttagta cgttatgtca attgggaagg
     8101 ctatgaaaat aaaaatccgt atgtagaaga agcttgtaac gagttgattg attatgtaga
     8161 gactcatttt tttaaaagaa gatattcgga agatgaaaag tcctttatca tacgagaaat
     8221 agagatcgca atcggaagaa aggcatttcc ccttggactg aaagaagaag ataagaaaag
     8281 cgcagaaacg aagccgttat ttcaattagt ctgtcaagga ttggaagagc aaaaaggaat
     8341 tctagactta caagaagaag atgtctatta tattttttct ttgttcaaca gtagaaatta
     8401 taccaatgag aacatggagc tgttaagaaa agatttcgaa gttgtttata aaaattttgt
     8461 tctcaatgac ctatcactga atgaattgat tttacagatt attagtatcg ctgaaatcga
     8521 cgatgcagaa aattttattt tcaagcaatc ctttttacaa tttgtccgta cgttgtgggc
     8581 agatggacaa gtatttttac cggaaaggat ctatcttcta tcagaaaaag aacaacttct
     8641 gtacggaaaa attgtagaaa tattggaaga gtggaaaaag aaaaatcaaa tccaactaag
     8701 atggaatgaa aatttcattc gaaaattcgt caaaagtctt tctttgatca acagtgaaca
     8761 agcggggaga caggaaatag aaatttttgt tgtttcagaa agttcagtca aacaattttt
     8821 ttatcgaacc caatttcatt tgtatgcgga agaaggcatc gctgaaataa atcctatttt
     8881 atttcgttca ttagaagaat tgcctgatga atgtctatgt gcgaaaaaaa gagtggtttt
     8941 gtgcgatgct gctagctatc aaaatggatt agaaactgaa aagacaaaga tctatccaat
     9001 ctcattaaaa ggtgcaaaca tccatttgta tcatattgct caggaacttc acctattaaa
     9061 aaaacatatt tcttgatgag accttaatta ggagaccttc tacaaagctt tttaattgtc
     9121 tgtagaaggt ttttatttga gtcctgattc gtgcgaagat ctacttatat aacaagcttt
     9181 ctctgaaatt tttttaaaat gctattgact tagagtcaac tctaagtagt agaatagata
     9241 aagtgtaaca aatctatttt cattaaaaga agatagtacg gaggagagaa tgtattatga
     9301 gtacagtatt acatgtattg gatgcaatca atagccccgc agatgtcaaa aaattatctg
     9361 ttgaggaaat gaaacagttg gcagaagaga tgcgccaaaa aatcttgcaa aaggacagcg
     9421 atgtaggtgg gcacgttggt ccgaatctag gtgtagtaga attaacgatt gcgtttcatt
     9481 atgtatttga ttcaccaaag gataaaatcg tttgggatgt ttcccatcag tcttatggtc
     9541 ataagctttt aactggtcga aaaaatggtt ttgaaaaagg acattaccgt gaagtgagcg
     9601 gatattccaa ccaacatgaa agtaaacatg actattttac agtggggcac acatctacat
     9661 ctatcagctt agcaacaggt ttagctaaag cgagagatct gaagaaagaa tcaggaaatg
     9721 tggtagcatt tatcggtgac ggctccctaa gtggtggctt agcttttgaa ggattgaaca
     9781 atggtggtgt tttacaatcc aatctaatcg tattagtaaa cgataatgag atgtctattg
     9841 atgagaatca tggcagttta tataaaaact tagctgagct tcgtcaaacc aacggtaaaa
     9901 gcagcaataa cctatttaaa gcaatgggat ttgattatcg ttacgtggat aatggaaacg
     9961 atctggaaac ggtgatccgt ttatttgaag aagtaaaaga tattgatcat ccgattgtac
    10021 ttcacgtcca tacggaaaaa ggtcgcggtt atcagccggc aatcgataat aaaatgaaat
    10081 atcattggca tgtaccattt gatctgtcca ccggggaggc aaagcaagta acttctggag
    10141 aaacatttaa tatgatcatc atggattatt tggataagaa aatgcaaaca agtacagctc
    10201 ctattgccgc agtcaatgca gcgataccag gcgcctttgg actgaaaaca ttccaagaaa
    10261 aacatccaga tcattatttt gacgtgggga tcgctgaaca gcactctatc actttcgctt
    10321 ctgctttggc ttctcaggga gtacgtccag tcgtcttcca atcaagtact ttcttgcaac
    10381 gggcatatga tcaattatca catgatttag cgatcaacga gaatccagtg attattttag
    10441 tcggtggcgg aacgatctca gctagtgacc gaacacacca aggaacattt gacattcctt
    10501 acttatcaag tatcccgaac atcaaatatc ttgctccagc aacaaaagag gatatgatct
    10561 ctatgctaga ttgggcgttc gaacaaacag cgcagcctgt agcaatccga attcctacac
    10621 atggtgtaga acatggtaca gctatcgcaa atgattatag tattccagcc tatcaaacag
    10681 taaataatgg aggaaaagta gcaattttag ctttaggcgg ttttcttgaa ttaggaaaag
    10741 aaacagtaaa agcttttaga aaaaaaggaa tcgaagcaac gttgatcaat ccaggaacga
    10801 tcacagaaaa tgacgtagaa acattagata aattaaaaga aacacacgaa ttagtcatca
    10861 cattagaaga tggtagtttg tcaggaggat ttggcgaaaa tatcagtcgt tattatggtg
    10921 attcttcaat gaacgtatta aattttggtg cagagaaaga attcacggat agcgttcctg
    10981 tagggcagct ttatgaacgt tatcatttaa caccaaaaca aatcgttgaa gatagtctgc
    11041 gtgtcttgaa tattcaataa ttcattatgc tcaccatcca gataattgtt tatactagta
    11101 tctggatggt tttttcatta taaaaagcaa aggggtggat gttatgtatc agcaagtaga
    11161 agaatatgtc aaaaagttcc aagaaaaata tcctagttat caatcagaaa aattaggttt
    11221 cttttcattt ggggatacag aaaaaatggc agacgagttg agcgaactag ttgtaaaaaa
    11281 gataaagact ggtacatcaa gtggttacga tctgtataaa caagagaatg agcctttacc
    11341 aaaagttggt caattagacg tggtcctgaa tggaaaaaat gaaccagttt gtatcatcaa
    11401 aaatataaat gtgaccatct tgccttttag tgaagtcacg aaagagcatg cttggaaaga
    11461 aggagaaggg gatcggacat tagcttattg gcggaaagtc catgctgagt tttttaaaca
    11521 tgcttataaa gaagcgttga acatagaatt tacagaagag aagctggtcg tatacgaaga
    11581 atttgaagta attttctttt agtaagaaag gtctgctgaa agaaatagct cattattgtc
    11641 tcctgaatag aaaagggtta catttttata tgaagctgta tttttatata acattactgg
    11701 aggagatatt gtggatacac tggaacaaat caaaggcgga gtcgtcgttt cttgtcaagc
    11761 tttggaaaac gagccgctac acagttcttt tattatgggg agaatggctt tggctgcaaa
    11821 agaaggcgga gcagttggta ttcgagcaaa tacgacagaa gatatcaatg aaatcaagcg
    11881 aatcgttgat ttaccggtaa tagggattat caaaagagat tacgatgggt cagaagtgtt
    11941 tattactgcg acagaaaaag aagtggaaga acttttggag acgcaagcag aaatcattgc
    12001 actggatgca acttctcgta aacgtccgac agaaaaaaca actgctgaac ttgtccaaat
    12061 gattcacgaa cacggtcggt tagctatggc agatatttcg acttttgagg aagcgcttca
    12121 agcgcaagaa gatggttttg atcttttgtc tacgacttta gcaggctata cagaatattc
    12181 acgaaagacg cagacacctg attttgattt attgaatcaa atcatagaac aagtcgatat
    12241 cccagtaatt atggaaggac atactgactc tcctgaacaa gtagagaaag catatgaatt
    12301 aggtgctttt tcagtcgtag ttggatctat tatcacccgt ccgcaattga tcactaaaag
    12361 atatgtcgaa gccgcaagta aagcaaataa ctaaaaaaca cgcacggcac agattcttga
    12421 caaaaaagaa aaattgatag atagtttaaa gcagattcta agaagatgaa aaaagcatta
    12481 cttttcattt tgtcttcaag atctgctttt taacgaattt tatagaaaga aggcgaaacc
    12541 atgtttgaac ggagtccttc agaattgaca gaacgtgaaa attacaagtt gctgattggt
    12601 tcagtcatcc ctagaccagt agcagtagta acgactaaat cagcaaaaga tatagtgaat
    12661 atcgcaccct tcagttactt caatatcgtc agttcgaatc gacccatctt atccttggcg
    12721 atccagagaa aacaagatgc agtaaaagac acagcaaaga atattcttga gacaagagaa
    12781 gctgttatcc atatccttga tgaggacaac gtagaagaag taaataaaac agcagccaat
    12841 ctgcctaatg aggaaagcga actgtacctg actgacttga ctttaactga ttcagtaatc
    12901 atttcagtac cagcattgac agaagcaaaa gttcgttttg aaacatcctt atatgaacat
    12961 gtcgagatac ggaataaaaa taaagtaaca gctgatttat ttttgctaga agtacagaaa
    13021 tatcatttaa atgaaacagt ctatgatgat aagacaggaa ggatcgatcc aagaaaattg
    13081 aatgctgtaa gccgtttggc aggaaatgat tatgcagcaa taggagaaat tttcacgatt
    13141 gcacgtcccg aataaaaagg agcactagtt atgttaaaaa taagctataa accatcgaca
    13201 gattcaaaag aaatgaaaaa agaatatgaa acagtgaatg attttctgca agggcagtac
    13261 ttagaagttc cgccattgca agaccatttt gtcgttacta ctgttacttt agatggtaag
    13321 gaaatagaaa tgccagatca aacgattagc ggattgttta attactttaa caaataaata
    13381 tttattccga aaagtgaaaa aacatataaa aaaacacata aaactaaaaa attatcaaag
    13441 aatcctggtg caactgaaag aatttgcaac gggattcttt caacttattt gttatttttt
    13501 tctaaaaaat attaaagatt gttaaatttc actatttcat ttcaaattcc attgcctaat
    13561 cattaggaaa agtctatcat gaactcgtaa atagaatata gtaataacct tgttaggtga
    13621 ggctcctata caaacatagg ctgttgccca gaaacgtcga aagtcgccaa tgggtaaaac
    13681 agaaactgtt ggattaaggc tttttccaat agctaagaat gttttcttta cgttgtatag
    13741 tgctaaaact cggacgatga gatgatgcta ggtcagaatt cttgttcgaa aaggtttctg
    13801 accttttctt tatatttttg tgactgactt atttgatgag acaaactcgc tcctcacctg
    13861 acaagtggat tgctgtgtga ggaggagatg cggtgaaaaa agatcgattg gtggattttg
    13921 ggtccttatt tgactttgtc catgatcggt cttttagaag tatacagtgc cagttcttat
    13981 cgtttattgc aagccgatga aaatacaaaa agtctattat tgcgtcaact aattttcata
    14041 tttttgagtt ggagcgtgat cttcttagct cgttcagtca aactacacta tttacttcac
    14101 cctaaaatag caggatacgg tttagcctta tcgattttct ttttagtatt agtaagaata
    14161 gggatattcg gtgtcactgt caacggcgca caacgttgga tctctctgtt tggcattcaa
    14221 ttccagcctt ctgaactggc aaatcttttt ttgatttttt atttaagctg gttttttcgt
    14281 gacggaaata gtagcccaaa agatctaaaa aaaccattcc tgattacagt aggtataact
    14341 tttctgattt tatttcagcc aaagattgct ggagcattga tgatcctttc gattgcgtgg
    14401 gtcatatttt gggcagcggc ggttccattt aaaaaaggga tctatctaat cgttactttt
    14461 tctgcattgc tgattggagc agcaggcggg gtattatatt taggaaataa aggttggctt
    14521 ccacagatgt ttaatcatgc ttatgaaagg atcgcgactt taagagattc ttttatcgat
    14581 agtcatggtg cgggctatca aatgacccat tcgttttatg cactatataa tggtggcata
    14641 tttgggcggg gattaggaaa tagtatcaca aaaaaagggt atcttccaga gacagaaaca
    14701 gattttattt tttcgattat tacagaagag cttgggctaa tcggtgcatt gtgtgtgctt
    14761 ttcttattgt tctcattatg catgagaatc ttttgtttaa gcagtcgctg taaaaatcag
    14821 caagctggat tgtttctttt aggattcgga actttgctat tcgttcagac gataatgaac
    14881 gtgggaagta tcgcggggct gatgccaatg actggtgtgc cattgccatt tgttagctac
    14941 ggaggaacaa gttatctgat cctttcttta ggaatcggaa tcacgttgaa tatttcttca
    15001 aagatacagg ccgaagagtt ggcgctctat cgacctgaaa aacaataaag agaaactgag
    15061 aaactctcag tttgaattat cataaagtac aatcttttat ttttcaagcg agaggttctt
    15121 ttagaaagag gaattcgcaa tgaaagtatc tcaaaaaatc atattatcta ttttgttact
    15181 gcttacatta gtagttggct atttttcgat tgagtttatc catggatttt cgtctgcaaa
    15241 acagagttca actgtgaaaa aggtagagcc gaaaagtatc cctaccacac taaatgtggc
    15301 tttgattggt tcagatgctc gttcgaaaga cgaaaacggt cgctcggatt cacttctggt
    15361 tgcacaatac aaccagaaaa cacaacaagc aaaactgatc tctatcatga gagattcata
    15421 tgtcgatatt ccaggttacg gaatgaataa gataaatgca gcttactctt atgggggagt
    15481 tgatttatta aatcaaacat taaaggaaaa tttcaaattt gaagctccct attatgcaag
    15541 tatcacattt caagatttta tcgattgcgt taatgaactg tttcctggtg gagtcaagat
    15601 cgatgcagaa aaatctctag atttagatgg cgtatatata aacaaaggag agcaagtgat
    15661 ggatggtaat actttactcc agtatgctcg atttcgggaa gacaaagaag gagacttcgg
    15721 gaggatcaga aggcagcagc aagtgatcaa agctatctct cagcagctga aagacgtaac
    15781 ttcaatattc aagctaccca aagcggttgg gaaattactt ggtagtatcc aaacgaacct
    15841 tccagaaagt gtgcttctgg attgtggtat ggatttcctc aaagacatat gttagaataa
    15901 acaggtataa atagtgaaat aaaggaatga caagcaagag aaggaggaaa aaatgaaaag
    15961 aagtgacaag cacggcaaaa atcgaacagg cgcttatatt gccggcgcag tgatcttaat
    16021 agcagctgcg ggtggcggtt atttttacta ccagcactat caagaaaccc aagcagtaga
    16081 agctggagaa aagacagttg agcaatttgt ccaagctttg aacaagggag attataacaa
    16141 agctgcagaa atgacatcaa aaaaggcggc aaataaaagt gcattatctg aaaaagagat
    16201 cttagataaa taccagaata tatacggtgc tgctgatgtc aaaggacttc agatatcgaa
    16261 tctaaaagta gataaaaaag acgattctac ttacagtttt tcatataaag caaagatgaa
    16321 tacctcatta ggtgaattga aagatctttc ttataaagga acattagaca gaaatgatgg
    16381 tcaaaccacg atcaactggc aacccaactt ggtttttcca gaaatggaag gaaatgacaa
    16441 agtaagcctg accacacaag aagcagcaag agggaatatt atagatcgaa atggtgaacc
    16501 attagcaaca acaggcaaac taaaacaatt aggagtcgtt ccaagtaaac ttggagatgg
    16561 aggcgaaaaa acagccaata tcaaagcgat tgcttcctcc ttcgacttaa cagaagatgc
    16621 tatcaatcag gcgatttcac aaagctgggt acaacccgat tactttgtcc cattgaaaat
    16681 cattgatgga gcaacgccag aacttccagc tggagctacc attcaagaag tagacggcag
    16741 atattatcct ttgggtgaag cagctgctca gctgattggt tacgtgggag atatcacagc
    16801 agaagatatt gataagaatc cagaattaag cagtaatgga aaaatcggtc gctcaggttt
    16861 ggagatggct tttgataagg atcttcgtgg gacaacaggt gggaaattaa gcattacaga
    16921 tgcagacggt gtagagaaaa aagttctgat cgaacatgaa gttcaaaatg gcaaagatat
    16981 caaattgaca atcgatgcga aggcacaaaa aacagctttt gacagtctag gaggaaaagc
    17041 tggatcaact gttgcgacaa cgccaaaaac cggtgatctt cttgcgcttg ctagctctcc
    17101 aagctatgat ccaaacaaaa tgacaaacgg gatctcacaa gaagattaca aagcttatga
    17161 agaaaatcct gaacatccat tcatcagccg atttgcgaca ggttatgctc ctggatctac
    17221 gtttaaaatg attacagcag caatcggtct cgacaacggc actatcgatc caaatgaagt
    17281 gttgacgatc aacgggctta aatggcaaaa agacagttct tggggatctt atcaagcaac
    17341 gcgtgtcagt agtgatgtat cacaagtaga cttaaaaact gctttgatct attccgataa
    17401 tatatatgcg gcacaagaaa cgttgaaaat gggtgagaaa aaatttcgta caggcttaga
    17461 taaattcatt tttggtgaag accttgattt gccaattagt atgaatccag cacaaatttc
    17521 taatgaagat agctttaact cagatatctt gctagctgat actggatatg gacagggcga
    17581 acttctaatt actcctatcc agcaagcagc aatgtattct gtttttacca acaatggcac
    17641 acttgtctat cctaaattga ttgcagataa agagacaaaa gataagaaga atgtcatcag
    17701 cgaaacagca gtacaaacga tcgtgccaga tctgagagaa gttgtgcaag atgtaaatgg
    17761 tacagcacat tctctttctg ctttagggat tccgttggca gcgaaaactg gtacagcgga
    17821 aatcaaagaa aaacaggatg taaaggggca agagaacagt ttcttgtttg ctttcaatct
    17881 tgataaccaa ggttatatga tggtcagcat gttggaaaat aaagaagatg atgattcagc
    17941 aaccaaacga gcatcggaac tattgcaata cctcaaccaa aattatcaat aaaaaattgc
    18001 tttttaagta cagtaaaagg actgtggcgt tatcgtcaca gtcctttttt caaataaacg
    18061 gttttcacga tgtctctttc acaacttctt tttgatttac tcacacttca taaacttttt
    18121 ttgtaaaata tttgagaaca agtggagaaa taagtgtact taataaaatc acgataacta
    18181 aaggtgaata gtactgtggt tcgatcaatt gactttgctg tccaatttgt aaaatgatca
    18241 aagccatttc tccacgcgaa atcataccag caccgaccat caatgaacta tgttgagaaa
    18301 aaccggcaat ctgagcacca aaataacctc caagcaattt ggtcaaaatc gctacaagcg
    18361 tcaatataga aataaagagt agttgttcac taaagtcaga aaaatcaact tctaatccta
    18421 cactgacaaa aaatactggt ataaatactg catatcctaa agcctctaca ttgtggtata
    18481 cttcttcttt aacctttgtc tgactgacag ctatcccagc aaaaaaagca ccaatgacag
    18541 agctaagccc aacaagatcc gctacgtaag acattcctaa acaaataact agcgatacga
    18601 tgataataga agaatttgcg tacacttttt ctgcaaatga aagtaggaaa ggcgcaatcc
    18661 atttgactaa taagaaaata aaaacaaaat aaattagctg ttcaatcaaa acaagcggta
    18721 aagaagcatt gctagaagct tcccccgtta gaaaagatag gctgaaactt agaactaaaa
    18781 cgactaaaat gtcatctacc acagaagcac ccaaaattgt tgatccttct tttgtattca
    18841 ctacgtttag ttcttttaat acttctactg aaatactgac agaagttgcc gcaagaataa
    18901 tcccaaagaa aatcgcttca tttcccgaaa cttggaatgc tttgcctgtc aaccagccaa
    18961 aaacaaccgg gaagatgatc ccaagcaaag caacgaacat accaggtcgg aaatattttt
    19021 tcaaaagaga taaatcactt tccagaccag ctaaaaacat taataagatc acaccaatct
    19081 ccgaaaagtc atggactaga atatcaggtt tgacccaatt caatccagct tggcctagca
    19141 aaacaccaac aagtaattgt ccaatcactg ctgggatacc taatctccgc gagatatgtg
    19201 agccaatcgt tgttgaaatc aatatcaggc ataaaatacc aataaattcc attctcatca
    19261 ttcctttgta taaaatatag cccgaactta gcataacata cattattgaa aaaataggaa
    19321 aatatactca caaaaaaacc aacaatccaa aagatttttt tggattgttg gtttttatac
    19381 ggtctatttt aataactaaa aatgattaac gtatagtcat ttttcttatt ctgatgaaat
    19441 tgataatctc ctggatgccc atgaaaatca aaataaagcc gaatatttgg aatagaagca
    19501 tcaaactttt gaatggattg aacaataaga cgaatccgcc aatcaacaac agaatactac
    19561 tataaacact ccaactttta gcttttgtat tcatgctgaa gaacaactgg aacaagctgt
    19621 tgatgataac agctaatcca agaagaatcg gcaggataga aacgattgca ggtgcaaaag
    19681 catagacgat cagagctaag atcaggaaaa aaagaccact gaacagaccg atactccaag
    19741 aacctgtttt ccttttaaaa cggtaagcct caaaaagatt caacaaccca agcaaaacaa
    19801 gataggcggt gatcagataa ccgataaaat gaaaaacagc agaagggttt agcacaatcg
    19861 caatcccaga aataatataa acagcagctc ttaataaggc gtatttttga atattttgtt
    19921 taatcgtctc aaacatataa gaaaacctcc tttgacttat tttaacgtga actagtcatt
    19981 ttaccaaatt aaatgttaca aaatgagcga aggagaagaa tatctctgga aaaatcaact
    20041 tctgaggatc ttttccattt ttttgccttt tgctagctca tcgatcattt tatctaaata
    20101 acgaatttct ttcatcaagt tatcctcgat gtcttctact cgtacaccac aaacaacacc
    20161 tgtaatcaag gaacgtgaag gattggggac aggggcttcc gcaaaaaatt gttcgaaagt
    20221 cacttgtttt tgtagttgat attctagttc tgtttgggaa taacccgtca gccaacaaat
    20281 gatttcatct acttcctctt ttatacgatc ttttctctcc gcttttgcta catacatagg
    20341 ataaacgctt gcaaaacttg tcgtaaaaat acgattttgc gccataatca gtcacctttc
    20401 tttttttcaa attatttact acttatagta tataagaaaa agagaagaaa aagcgattat
    20461 tcaaaaaaac aaaaaggatt gtgacaaaat tcttgtcacc atcctttttt ccgctctctg
    20521 actttttaca atcttcatag ctcaagtgcg catcagataa tcgaatgctc ctaaagctgc
    20581 agtagctcct gaacccattg aaacaatgat ttgtttgtat ggactatctg tacaatcacc
    20641 agctgcgaaa acgccgggga tattcgttgc gccatttttc tcggtcacta tttcatttct
    20701 tggattcatt tcgatcgttc catctagcca atccgtatta gggagtaagc cgactagaat
    20761 gaatactcct gaaacagcta gtgtatgcat ctccatcgta cggcgatcga tataggagag
    20821 agattctacc tgattcgtac cgctgatttc tttcgtcgct gcatgtttga taacagtgac
    20881 attcgcaaga gagactagtt tatcctgtaa gatttgatct gcttttaatt ctggtaagaa
    20941 ttctagaaca tatacatgtt ttgctaaccc agccaaatcg attgctgctt caacaccaga
    21001 attaccacca ccgataacag caatctcttt tcctttaaat aaagggccgt cacagtgtgg
    21061 gcaataagca attcctttat ttttaaactc tttttcgcct ggtacattga tagaacgcca
    21121 gtgcgcacct gtcgcgatga tggcggtttt tgctttaagt gatataccgt tagctaagcc
    21181 aatattaata aaatgttgct ctttatttaa ggaaacggcc tgttgattca tcataatgtc
    21241 gatagggtaa ctacgcacat gactttctac ttgctgcatc aattttggac cttctgtgta
    21301 agaggtacca atcatatttt caatccctag tgtttcaacg acttgtccgc cgaaagaatc
    21361 agcgacaagt cctgtacgga ttcctttacg tgctgcatag atagctgcac tactagctgc
    21421 tggtccaccg ccaatcacta atacatcata aggttctttt tcaaacaact cttcttcaat
    21481 caaagggcca gtgatttttt caacaatttg ttcgatcgtc atgcgtccgc tactaaattc
    21541 ttctccattt aaaaacacag ttggcactgc catgattttt ttatcatcga tttctttttg
    21601 gaacatccca ccttcaatca tcgtatgagt aatatttgga tttaatacag ctaatatatt
    21661 caatgcctgt acaacgtcgg ggcaattatg acaagtcaag ctaacataac tgtcaaaatg
    21721 caatgtttgt gttatttttt tgattttaag actcaaagat tcactgattt tcggtgcccg
    21781 tccactaatt tgtaacatag ccagtaaaaa agaggaaaat tcatgaccga gggggatacc
    21841 agcaaaaacg attccacttt ctttgccaac tggattgata gaaaaactag gtgtgcgcat
    21901 cgaatctctt ttttcccaag agattttagg agacatttct gctatttcct tcgtaaattc
    21961 agctagtttt tgactatttt cactattatc caaactaaca gaaaaaacaa taggagattc
    22021 aatcagtgct aaatattgtt cgagattttg tttagtttct ttgtctaaca tatccaccac
    22081 ctaaatcttt ccaacaagat caaaacttgg tttcaatgtt tcgccacttt ctttccattt
    22141 tgccggacaa acttcacctg ggtgggtacg tacatattga gcagcgcgaa tcttatcaat
    22201 cagtgcacta gcgtcacgac cgattccatc tgcattgatt tccatagctt gaacgattcc
    22261 gtctggatca ataataaatg ttcctcgctg agctaatcct tgctcttcat ccaaaacatc
    22321 aaaaatacga gaaatctgat gagacggatc accgatcatc acgtattcga ttttaccgat
    22381 agcatctgat gtatcatgcc atgctttgtg agtaaagtgg gtatcggtag agcaagaaaa
    22441 gacttcaaca cctaaagatt tcaatgtact gtattgttct tgtaagtctt ctaattcagt
    22501 aggacaaaca aaagtaaaat cagctggata gaagcaaaga atactccagt tccccataag
    22561 atctttttca ctgacttcta aaaattctcc ttgatgataa gcatgtgcat taaattcttc
    22621 gatttttttc ccaatcaatg acatagtaaa acctccaata ataattattt atttataatt
    22681 attgtaattt agttggagtt gcaaagtcaa tggatatttt gttatttaat aaagattact
    22741 caaaaacgaa ggttaattat aaaaatagaa gaggtcgcaa gaaaatgcta ctgctggaaa
    22801 tactcgggat aacgttgagt aacagtttcc tgttctttca gcatcatgtg taagtgcaat
    22861 cccgtttgaa atcgagcttc ttctggtttt ttatcaacta aagccttgag taaatcataa
    22921 tgttgttcca tgatcgtttc ccatggaagc ccctgaatgg tcactcgtaa ccagcggaaa
    22981 cgttctaaat gggtattatg gtcatctaac cagttccaaa cttcttttct tcctgcaatt
    23041 tcgaaacaag cttcatgaaa taaattatct gcacggaaaa aagcgcgttc gtcatttatt
    23101 ttgactgctt tttcttgttc ttctaaaatc gtttctagca ctattcgtgt ttgtgtgtcc
    23161 aatttggaac aacattcaat catgatttgc tcttccaact gttctcggac aaagcgagca
    23221 ttttctgcag aaacaagatt aattttggaa acatacgtac cactttgagg tatcgtatac
    23281 acgagttctt gctgacgtag ttgaatcaat gcttcgcgaa tgggagtccg gccgatagca
    23341 agatgttcct ccagtgcctt ttcagatatt ttccttccag gttctaagtc agcatagata
    23401 atttgtttac gaatcgcttg ataagcttgt gattgcaagc tgcttttcat ctttattcct
    23461 ccaaaatcat ttctatgaac gtagtataac agaagaggtc tgaaaaacaa tctggtatgt
    23521 cacattaact agtaaatttg tataaatagt aaaattttgg ttgacatagc gatttttatt
    23581 gcataaaatt cacttgaata caaaaactaa tatgttagtt taggagggga aaaatgattg
    23641 atttaaacaa ctggaggaac tttatccctg aattatctca aaaagaagta gaaatacctc
    23701 attttgaccg tgcatcatta agagaaaatg gacaaaaaaa tcctgtctgg atccatttcg
    23761 gtggcggaaa tctttatcga ggatttcatg cagaaatcgc tcaacgttta gcggatctag
    23821 gcgaattgtc cactggtgtc attgtttgtg aaacattcga tgaagaaata attgaaaggg
    23881 cttaccaaga ttttgatgat ttgattcttg aagtggtcat gccaagcagt ggagagttcg
    23941 tcaaacgtat attagctgcg acagctgaca gtctgtattg tcatccagat tgttctgaac
    24001 actttgataa gatgattcga cactttgaaa atcctagttt acaattagtt acttttgcta
    24061 ttactgaaaa aggttatcga ttgaaagata caaataataa atatatagga ccgattgcag
    24121 tcgatataaa aaatggtcca aagaagccat cacatacaat gagtattctt gctgtgctac
    24181 tttataaacg ttttttatct ggagcttggc cgattgcact tgtctctaca gataattttt
    24241 cacaaaacgg tagtcaatta cgtacttctt tgctaacgat cgcaaaagaa tggcaaaagg
    24301 aaggttatgt acaaaataca tttatccaat acttatcgaa tgaagaaatt gttgcgtttc
    24361 catggacgat gattgatcgt atcaccccga atccttcctt gtcagttagc aaaatgttgg
    24421 caaaagaggg cttttcaaat atgtcgattt tccaaaccgc aaaaggaaat aatattgctc
    24481 catttgtcaa tacagaggac atccattatt taatcatgga agatcatttt cccaatggac
    24541 gtccgaaatt cgaaaaagct ggggtattct tgactgatcg tgcaacggta gataaagcag
    24601 atacgatgaa ggtgacgact tgccttaatc ctttgcatac gtctttagct attatgggtt
    24661 gtttactggg gtataggagc atagctgagg agatgaaaga tccagattta tcgctgctag
    24721 tttctgaaat cgggtacaat gaaggcctcc cagttgtgga gtctccaggt atcattgatc
    24781 caaagatctt tctggaagaa gtaattactg tgcgcttttc taatccaaat attcctaata
    24841 tgcctcagcg aatcgccacg gatacctctc aaaaggtggc gattcgttat ggtgagacga
    24901 ttaaaaaata tatggaaata gaagttaaag acccgcagac acttgtattc ataccattga
    24961 ctctcgctgc ttggcttcga taccttattg gcattgatga tcaaggaaaa ccattcatcc
    25021 cgagtccaga cccactattg acagaccttc agcataagct ttccgatatt caactgggta
    25081 cgcaagatac atcacatatt catgagaaaa tggctcctat tttgtcaaat aaagaaattt
    25141 ttggtgtaga tctttaccaa gcagagcttg gcagaaaaat agaagaaatg ttcatcaaga
    25201 tggtagcagg accaaatgcc gtacgaaaaa cattacagga ttacttacaa gaacatggag
    25261 gaaatttatc atggaaatga cttttagatg gtacggatca caggaagaaa agattacctt
    25321 agatgaaatc agacagattc ctgcggtcaa agggattgta ggcacattga tggatatacc
    25381 agtaggagag gtatggccta gggagaggat caaagaacta aaagaagaaa ttgagtctcg
    25441 tgggttaaca ctaaaagtaa ttgaaagcgt caatgtgcat gatgccatta aaattggatt
    25501 accttcccgt gagcagtata tcgaaaacta taagcagaca atccgaaact tggcagaata
    25561 tggaatagaa gtcatctgct ataattttat gcctgtattt gactgggtga aatctgacct
    25621 tgactaccgc ttagaagacg gctcatccac gttagctttt atatctgatg atattccaga
    25681 tgatccaaga gaaatcgtcg cgcgcatcga acattccagc aatgaatttg gattgccggg
    25741 atgggaacct gagcgcttag ctcctatcaa atccttgctt gaagcctatg catcagtaga
    25801 cgaagaaaaa cttcgagaaa attttgccta ttttctccaa tcaatcatcc caacatgtga
    25861 agaggtaggg gtcaaaatgg ctgtacatcc agatgatccg ccatactcga tttttggatt
    25921 agctcgaatc gtaaagaatc gagaagattt agattggttg tgtcgcatag tagacagccc
    25981 ttataacgga atcactcttt gtacagggag tattgcagaa gatccagaaa atgatgtata
    26041 tgggatttta gcagaatttt gccaaagaga tcgaatccca tttgcacatg ttcgaaatat
    26101 taaattttta gctaatcgag atttctatga ggcaccacat aaatccgaat acggttcatt
    26161 agacatgtac cgcatactaa aaacaatgta tgacaacgga tttaacggat acatccgtcc
    26221 tgatcatgga agaatgatct ggaatgagac aggaagacca ggatacggct tatatgatcg
    26281 agcattaggt gctgtttatc taaatggatt atgggaagca atcgaaaaag gaaacaaaag
    26341 taaagataat tagtgaaaaa aactgtaatt ttattatgta aataagaagg atgttcaaat
    26401 tcttgataca taaatccgga ggttgttaat aagcattcgg atttatgtat cttatttggt
    26461 ctaggaagta acttgatttt cttttttcga ttgatccatg agtgcttctt cttttaattc
    26521 aaagatatat tctgagatcc tcataatcac ttttttccag tcttctggtg tgatgattcc
    26581 ttttaaaata tagatttttt tgatatgaga aggcaattgt ttcaaagggc agtcgctgat
    26641 aacgatgttg cagttctcca taaaatcatt ttgtattttg atcgattcat ttgaaaaaat
    26701 ttgttctatc ttaacgatca gatctttact gatataaaaa tcacgcgtat agttcacacc
    26761 aatcacaatt cgcggctgtt ttttgtagcg atcatacaaa tgtactaggt cttcaaccat
    26821 ccattgcaca ttttcctttt ctaaaataac tggtaacaag tgttgatttt gttctctgaa
    26881 atccatataa aattgttcaa tggcggtttg gacttctttc aatacgctat gttcttgata
    26941 aagcatgaaa gtaggaaggg gcgtatttgg ttgattgaag ttaagaaatc cattataaag
    27001 tttatttcgt gcgaatgcca atgagtaaag aatcttttct ttttcaggta taaacaaatc
    27061 aaatacagta caaagggact ccaccatttc tcttgaataa agaacatgag gaacgtttgc
    27121 tttttttaaa agtttgtatt gctccaagct tgtttcttcc gattcgattt tcgtgataga
    27181 aagtcgagct aaaatattca ctaagatgcg ttgttcgcga caaattggca gattaggtcg
    27241 caaaatatct acagagagat caataaaaaa gtcaatatat tcatactctg tgaattcttt
    27301 ttgtacgtct ttcacagaag ttgcaggaaa attctcttta catattttta atagaaaata
    27361 taatttatct atcataccgc tatttagtcg gtcaagtact tcttttttaa aaaaagtatt
    27421 catcataaaa gccactactt gcggatcttc atcataaaat tctgtagcag tacttgaaaa
    27481 gatgttccaa taaatatcta atgctgcata ttgaatttgt acctcttttc cagaaaaaga
    27541 ctttctgcca ttattagaaa aggagataga caaaccgtac tatgctaaaa atgcattaat
    27601 ctttttcatt ttcgtataca aataagaggc actatagttt gtttgctgac tgaaactgat
    27661 aatcgaattt gtctgacagc tgaacaaaga agtcaagatc tgataactga ctgattcgtt
    27721 gcagtatctt ccaaatagac gataatagca gtaagccgga tcaattcctt caaaattcaa
    27781 ctttaaaaaa ggtttttgct tatcaatatg cagttctgtt agattgagac gctcaaagtc
    27841 ttgttctaat tctttgatgt atagtaaaaa atttgattca gacatatgga aatgatctgc
    27901 taaatattgt gtagtaataa agaaacgatg ttcagatagg aaaagaaaaa tatctaattt
    27961 tgtattgctt tttttcttca agataaacgt tttaatcgct tcttgagttt gcatgaaaga
    28021 ggctcctttt tacttaaatt gttaaaactt gaaaatatta ctgttttttt cataaattta
    28081 gacaaaaaaa cagtaaacat ataggtagaa tctctactat cttatttctt gcatacaaaa
    28141 aaatcaagga gtgagagagt tatgagatat tcaaccatct taatatcaac atttgcagcc
    28201 ttaagcttat cgcttactat aaatcagaca gtccacacag aggagacaga aacagccaaa
    28261 tggacagaaa ccaagtgggc caacgtcaat cgaattacct ttcaggatga attttcatcc
    28321 ttcaattcag gagtcgcaaa attaagaaaa ggacaaacag cgaccatcaa agcaaaaatt
    28381 gactattcgg gagacttagc acctatacta caatcagctg ttacatttga gaatgttgat
    28441 cccactttgt cgattggcta tgacgagaac actttgacta tccaacacaa gcaagcgata
    28501 tttaccttca ccgttacatt aaatcaggac ttgttaaaac cagcgctttt tactgtcaag
    28561 gtatcagatg gactaccgaa cgatcatcat ttaacgccgt atagtcagcg gcagacaatt
    28621 gagcaagatt cagccatcga ctcaggagga gatcttgttg aagaaccaac agataaacca
    28681 gaaaatgaaa ataagccaga agtaccgcct acagaaaatc cagacggaga acagaaaccg
    28741 gaaatagaac ctggagaaga acccgataca gaaactcaac cagagccaga caataaatca
    28801 aaacctgaaa taacccctgg agaaaaacca gatgtaactc cagaaccaga tacggattct
    28861 ggaaaccaaa cagtaccgga aacaaatcca gacacagata atgaaactga aaatccagaa
    28921 aaaccagagg tagatccaga agaaaaacca gatgtgactc cagaaccaga tacggacgca
    28981 agagaccaag gaataccaga aaaaataaac aaaaaaacaa ttcaagagga tggaaaaaaa
    29041 gagagtaaaa aatcaaatct agcaattcta aaaataaatg aagagcagct gaataaaaaa
    29101 tcacgaatat ttgatagcgc ccaatcagct gaaaccttaa aaagtagcaa ggatacaacc
    29161 tttgctgtcc tgaaacgaaa aataaacagc taccaaaatc cggagagtca caaaacaaag
    29221 ttatactgtg gagcggaatc attctattaa gtatagcaac aatgctttct gcaaaaagat
    29281 ttaaacaaaa cagatctctc taacatttga ataatgtctg tgaacgcatt tttcaaataa
    29341 aaagaaatat ccagaaaatg accccaaaat accagattga aatctgatat ttggggtcgt
    29401 tcatacttta tctttcttca tatttatttt aagggatatc tgtttctttt ggaagatggt
    29461 tcgggatctt tttcactttc aatacatcta aaaagaaggt aaagatcgga atgccgacaa
    29521 tcaagcccca aacgccaaag aaccgttcgc taacaagtaa gaccacaaat gtataaaaaa
    29581 tcggcagttc tgttttgctg gacatcaact tcggattcag cacataagac tcaattagat
    29641 ggacaatcaa aatcgtaatc aggatataaa caacatctcg gatgcctcct tgggaataag
    29701 ctatgaaaga tagaggaata caagaaatga taacacctgc tactgggatc agacttaaaa
    29761 tgaaaatcat gatcgctaaa ctcagcagct gatgaaagcc aaatacagcc aaggcgattg
    29821 tagtgagcaa cgtatttaaa agagcgacaa caaattgagc ttctaatacc aaaccaaatg
    29881 tattgacaaa cttatcggca aaatagtaaa tatcttgaaa gaaccaagaa aattcacttt
    29941 ttaaaaacaa tcttgagaat acaattgttt ttttcttttc aatcataaaa aagaaactta
    30001 agatgaatga catagcaaac gccactgcca tttttcctat atcctgtaaa tagccaagcg
    30061 caatcgaagc gccattttga agctgttcaa aaaaatcgtt tcgctcaata taagtatgga
    30121 tatattgtaa aacaggatct gcatcttttg gctgatgctc gtaaaaatta ataacggact
    30181 ggatcatgtc aaatgtttga tgaataagca tcgggatata ctttgtgaat gccagataga
    30241 taaggtaaac gatcagtgta taaatcatga tagctaaaac acctgtaggg attcggacaa
    30301 atcgctgaat gatttgaaca agatgaatca tcaaataagt aaagataaat gtgagcaaaa
    30361 tggttgtaat catacttcta actaagaaaa gaacaaaaac gacaaataat aaaacagtga
    30421 gacggcgtat tttttcattc gccaaaaaac gctgataaac ggtcaaatcg acaacctcca
    30481 aataacaaaa aataaacacg ttattcatta tatgatggaa tatgaaaata agaaagagca
    30541 aaaagaaaaa ccgctaaatg acgttatctt atgagttggt tttcctcata aaatcgttca
    30601 tctagcagtt tcagcccttt ttctggtctt gatgaaaatt atctagcatt tttcgggtca
    30661 gatgttgcag tgtatccaat tcttcctgtt caagtggaag ataagacttg atcttttgtg
    30721 gaataccttc tgcttgtttt tgcaacgcag caccttgagc agtcagcgta acatttacga
    30781 ttctttcatc acccgtttca cgctgacgat taatataatt tttttctgct aactttttta
    30841 gtaagggagt cagcgtacca gaatccagac acaaatcatt tcctagctct ttcactgaag
    30901 tctttttctt ttcccataaa actaacatca caagatactg ggtataggta agattcagcg
    30961 gcttgaggag gggagtgtag tgtctaatga tttctttaga ggcggcatat aaaggaaaac
    31021 atacttgatt aactaaatat agatcttcca tttttccacc tccgctgttt tactatagtg
    31081 tatcatagcg gatttacaca aaaaagtcta ttcactaact gctttcagag taacttctat
    31141 atttccagct gtagcttttg aatacggaca cactttatgc gctgcctcta ataattcttg
    31201 cgtttcttcc agagaaagac cttcgataga tccttcaatc tctacaccta agacaaagct
    31261 cgtttcactt tctgaataaa gggaaacttg tgcactgaca gtagaagccc cagagatatt
    31321 tttttgctgt ttgatcaatt ctaatgcact gttaaaacat gcactgaaac cagctgcaaa
    31381 caattgttca gggttggttg cattttcgac gcgtttacca ggagctgcaa tattcaattc
    31441 gaatgtacga tcgggattat gcacttctcc agagcgtccg cctgtgttga tcattttcgt
    31501 agaatacatt tttttcataa aattaccacc tttaattata ttttatacaa ttgaatttta
    31561 cacaatataa ttgtggaaag caaagaaatg gattggcata agataaataa gagaaagcac
    31621 atgaaacaga cgcgctttct cgaatagcaa acatatacaa aaaatatcag agacaaaaaa
    31681 taatctcatc ataaacatta catatatttc tcaaaaagtt gttttctttc ttcaaaaatt
    31741 acttcacgat ggacctgatg aagcatccat aaataaccaa aaggatctct gaacattgag
    31801 ttagtcacac caaagtccat catttctgtc atttcttgaa tctctacaca gccatttcgt
    31861 aatgctttat tatgtgtgtc ctcgatatca gagacgatga tattgaacca gatcgtattt
    31921 ggatgttcag cagtaggagc agtcaaacca agagacgtgt tttcatccag catatggaat
    31981 ctcgtaccat acaaggtaaa aatgacttca ttattgcctc tagggtaatc tgttgcctca
    32041 atcagttgta tttcatcaaa gattgtttga tacagttcta gtgctttcaa actatcattt
    32101 aatacaaaat cgatttccgt tcctttatgc ataaagatct cctctccttt tcagtcgaac
    32161 agttactaga ttcttttatt ataccagcta aagaaaacgc attcaaaaaa atagcggatt
    32221 tacttaccaa ctcattcgat tggatgataa gtaaatccgc gtcccattac ttctgctacg
    32281 ctgctgacaa tgacaaaggc acttggatcg atttcttcta tcaatggttt cattcgggaa
    32341 aattcatgat cagtcacaac gatcaataaa acctcttttg actttcgatt atacccgcct
    32401 tttgcctcta gcagggtaag gccacgtcca atctcagcac ttaagcgaag gcggatgtct
    32461 tccaaataat gttcactcat gaccataaca gatttctttc gattgatacc tgtttcgata
    32521 taagtcatga caattgaagt gattgcaata gataaaatag cataaagaaa ctcttctatt
    32581 ccaaaaataa acagattaag agaaacaacg aatgcgtctg taaaaaataa gccaatcgaa
    32641 gtattcaagt ggaaatattt tttaaaaatg aggggaggga tcgtcgtacc gccgctagaa
    32701 gagttgtttt tatataaaat cgcaactcct aaagcaaaaa tcgcacttcc aaaaatgaca
    32761 gacaacaacc gatctgaagt aatcattgtt tctggaacta ttgcaatgat taaaggaaaa
    32821 accaagcttc cgaaaagtac tttaaaaaag ggttttttac ctaaaaatag aagagctagt
    32881 accaacataa cgatattcaa cactaaaata actatagctc ggtcaaagcc taaagcagct
    32941 tccagtaata ttcctagacc gctgacacct ccagcagcaa tatgatgagg ccctaaaaac
    33001 atattgatag cgactcctaa tatgaagagg gcaaaaataa tcttaatgta tgtccatata
    33061 aattgtctcg tttctttcat ttattcactt ccttaattca ttaataatac tcttatctta
    33121 ttataactta cttttcacct taagttaact ttaattaata aaaaaattag gctagtctaa
    33181 attattatgt ttcattcttc tagaatatac ttctacgcca aaaactgtta aaaaactttt
    33241 actttagaaa attggagaaa ttgatcgctt aagataaatt caggacacta aatagtacag
    33301 gaagtagact aaaactttta aaagttttaa gtctatctat ttggcaagtt taaaaaataa
    33361 aaattcggta tcaaaaaact gttaccgata acatttttga aagcgttgtc ttttgcttct
    33421 ctatcactta tagtgatgac gtcatattaa aacacaagga ggaaatcaat ggatacagct
    33481 gcaatttatc atcgaccgga aagtgaatat gcatttctat atacgaatac aagatttcgt
    33541 attcggcttc gtactaggaa aaatgatatc aaaaaagtat atgtgctatg tggagatcca
    33601 tataccataa caactgaaaa atggtatcaa aaacaacgac caatgaaaaa atgtctaagt
    33661 accaatgttc atgattattg ggaaattgaa gtgacgagcg aaacaagtcg cttacagtat
    33721 gcgttccatg ttgttgggga agataacacg gactgttttt acggtgatca aggaattttt
    33781 ccttatcgag aaaatgtgat tactgaacca aatttttatt ttcgaatacc ttattttcat
    33841 caaatcgatc gattcactat tccagaatgg gtaaaagaaa cagtatggta tcaaattttt
    33901 cccgaaagat ttgcaaacgg ggacaaagca aatgaccccg aacacacttt accttgggga
    33961 agtaaagatc cagaccgaga agactttttc gggggagatt tgcaaggtgt gatggatcat
    34021 ttggattact tgacggacct tggcatcaat ggcatctatt tttgtcccat atttaaagcc
    34081 acatccaatc ataaatacga tacgattgat tattatgagg tggatcccgc ttttggcgat
    34141 aaaaaacttt taaaaaactt gattgatgaa gcacataaaa gagggatacg tatcatgttc
    34201 gatgctgtat tcaatcatat gggtgtccat tcaccacagt ggcaagacgt tctcaaaaac
    34261 ggagaaaaat cgatctataa agactggttc cacatccgtt ttttcccagt agattcttat
    34321 cagatgactg acttaccaga aactgctgaa aatatcccat atgatacttt tgcttttact
    34381 ccattcatgc cgaaactaaa tacagcaaat ccagaagtgc aaaaatattt gctggatatc
    34441 gcaacttatt ggataaaaga attcgatatt gatggatggc gtcttgatgt tgctaatgaa
    34501 gtcgatcatc atttttggaa aaaattcaga gaagcagtta cagaaatcaa accagacatc
    34561 tatatccttg gagagatttg gcattcctct caagcttggc tgcaagggga tgaattccat
    34621 gcagtgatga attatgcatt tacagattcg attaaagatt attttgcaaa aaagaaaatc
    34681 acagcttcac aaatggtcag tggaatgaat catcagcaaa tgctttacag agatcaggtg
    34741 aacgaaggaa cattcaactt attagattct catgatactg ccaggatctt gaccctttgc
    34801 caaggtaaca aagaattgat gaagtctgtg atggccttta tgtttcttca aaaagggtct
    34861 ccttgtatct attacgggac agaaataggg atgactggtg aagatgaccc ggattgccgc
    34921 aaatgtatga tatgggagaa ggaggaacaa gatctagagc tattcggttt tataaaagaa
    34981 cttgtttctc taaggaaaca gttgtctaag attatttctg aaggttctac tcagtggcta
    35041 atagtaaatg atcgtgaaga taagctctat ttcacacgga aactagaggg acagatcatc
    35101 tatgtttact ttaatcagtc aaaagaacct tgggtagtag aacaggaaaa tgaggtgatt
    35161 cttagtcaaa attgtcagtt gttagaagac gggaaagcag agatacgaca atacggattt
    35221 ttgatcatgt gttgaaaact gttaccggta acaacaagaa agcgtttgca aatgaagatt
    35281 tgtgcccatt ataataaggg tgtaacagca cgttgaatac aaaggaggaa atgaagatga
    35341 aaaaaagaag tgtgaaacag ttgggtttag ggttaatctc tttaggaatc ttaggcggat
    35401 tagcggcttg tggcaatggt aactcttcag cagaagggga agccgatgaa ggaaaaacgt
    35461 taacagtttc cgttgattct ggatataaag attatataaa cgaaataaaa aacactttcg
    35521 aaaaagaaaa cgatgtgaaa atcaagctag tagaaaagga catgttcgat cagttggaat
    35581 cattagcgtt agatgggcct gctggaaagg gacctgacgt tatgatggca gcatatgacc
    35641 ggatcggtgc gttaggacag caaggacatc tggcggaagt aaaactggga aatgaagcag
    35701 cttacgatga aacagacaaa gcccaagtga cttatgatgg aaaaatctac ggagaacctg
    35761 cagtaatcga gacccttgtt ttgtactata acaaagattt agtcgataca gcaccatcaa
    35821 cgtttaaaga tttggagaat ctatccaaag acagtcgttt tgcttttgag tcagaagcag
    35881 gaaaaaatac aggattttta gctaaatgga ctgactttta ttattcctat ggtttaattg
    35941 caggttacgg tggctatgta tttggtgatg atggcacaaa tccttcagat atcggtttga
    36001 ataatgcagg tgctgtagaa ggaatctctt atgcaacaga ttggttcaaa aatgtttggc
    36061 caaagggaat gcaagacata aaaagtgcag gagacttcgc cagccagcaa ttcatgtcca
    36121 ataaaactgc agcaatcatt gacggtccat ggcaagcgca aacatacaaa gaaaacaata
    36181 tcaattatgg tgtagccaaa attcctactc taaataatgg acagccttat caaccgtttg
    36241 gcggaggaaa aggatgggta gtcagcaatt atgctaaaaa caaagacctc tctcaaaaat
    36301 ggcttgatta tgtaacgaat caggaaaatc aagaaaaatt ctttgaaatg gtaaatgaaa
    36361 tccctgcaaa ccaacaagct agggaaacag caaaggctaa aaacgatgaa ttaacaacag
    36421 ctgtgattga acaatatgaa acagctcaag cgatgccaaa catcccagaa atgggcgaag
    36481 tttggacagg tgcagaaaac ttgatgttcg atgcagcatc aggttcaaaa acaccaaaag
    36541 aatccgcaga tgaagcagta aaaacaatca gtgaagccat agaacaaaaa tactgattaa
    36601 aatgataacc gtccattttt ataaaaaatg gaacaggtgc ttcagataaa agtggcaaga
    36661 gcgagatgga aaattatctt gctcttgttg ccattatctt aaaagcagtt tgcggtttag
    36721 caagtttaga gggggcattc agatgcagca agataaaaca agcaatatca acgaaaaaaa
    36781 aatcacgctt tgttcactta ttccagggat ggggcagttt gtaaatggcc aagcttttaa
    36841 aggtatcgtt tttttcgcca tattcgtcct attcattggt cagatgcttc tgggcggatt
    36901 tcatgcattg gtaggattgg ttactttggg aagtatacca atggaagatc attcattatt
    36961 tattttgatt gaaggcactt tgcaattcat cattacaatc attttcttga ttttttacgg
    37021 tttgaatctt ttagacgctt atcgagtagc gaagatgcgt caagagggca aaaaaatcaa
    37081 tcggacgatg aaggaagtca tacataatat aggtgatgaa ggttttcctt atctattgac
    37141 acttcccgct tatcttctca tgatttttac gatcattttc ccagtcctag ttacattgtt
    37201 cactgcattt actaattatg acttcaatca tattccacca gccagtttaa ttgattgggt
    37261 aggggctaaa aactttttta gtatcttctt tttaagctca tatcgtaata ctttttttgc
    37321 agtcttttcg tggaccgtga tttggacttt atgtgcaaca actttgcaaa tcacccttgg
    37381 tattctcaca gcggttgttg ctcaccagaa atttattaaa ttcaaacgta ttttcggtat
    37441 cattttctta ttaccatggg cggtcccagc ttttattact atcatgagtt tttcgaatat
    37501 attcaacgat agcgtaggtg ccatcaatac tcaagtgatt cctttcataa accagcttcc
    37561 ttttgtagat atcagtgcaa tctcttggaa aacggacccg aactggacga aagtagcaat
    37621 tatcttagtg cagggctggt taggatttcc ctatatctat gtgatggtta caggaatctt
    37681 acaatcgatt tcagaagact tatatgaagc agcaaaaatc gacggagcaa atgcatggca
    37741 gcgcttttca aacatcacgc ttcctgctgt cttcctagtg gcagcgccaa catttattac
    37801 acagtatacg gggaatttca ataatttctc catgatctat ctgtttaaca atggcggtcc
    37861 cggaagcgta ggcggaggag ctggttctac tgatattctt atttcctgga tctataaact
    37921 tacgactgga acttctccgc agtattctat ggcttcagca atcacgttga ttatctccgt
    37981 catcgttatc tgtgtgtcat tgctggtatt taaaaagaca aatgcgttca atatggggga
    38041 ttaacaatga aaaaatttca ttcgagtgct cgattccaaa aacgactttc tcactttttt
    38101 acttactttt ttcttttaat actgtcagtc attatcatct atccgctttt gatcacagca
    38161 agtactgcct tcaagtcagg aaatattgca gcttttagtt tagatctttc aagtgactgg
    38221 actttaggaa actttactcg gctattcagt gaaacacttt acgggacttg gtataaaaat
    38281 acattgatca tttctgtcct aacaatgatc gtacaagtga ctgtagtaac tttggcgggc
    38341 tatacttata gtcgctatcg ttttatcggc cgcaaatcaa gtttgatgtt ctttttagtg
    38401 attcagatgg taccgactat ggcagcattg actgcctttt atgtcatggc tttcttatta
    38461 gaagcgctcg ataagtactg gttcttgaca atgatctata taggcggtgg aattccaatg
    38521 aatacttggc tgatgaaagg atactttgac actgtaccaa tagatttaga tgaatctgct
    38581 aaacttgatg gggcagggca tttcaggatt tttttccaga ttgtattacc gcttgtcaaa
    38641 ccgatgctcg ccgttcaagc attatgggct tttatgggac cttttgggga tttcatgtta
    38701 gctaagttcc tgcttcgaac acctgaaaat cagactgttg ctgtcggctt acaaacattt
    38761 atttctgatg tgacaaacca aagagtctct ctttttgctg ctggggcaat tttgattgca
    38821 ctaccgattt gtctattatt cttcttttta caaaagaact ttgttaccgg cctgacatct
    38881 ggcggaacaa aaggatagga gcagagtatc atgcaaacat ttccgttaaa ctatttttcc
    38941 gcattacgta cgccaactca agtgtttgcg ggacgcaaac tattatcatg gcctaaattt
    39001 ttcttgatat ttgtattttt agtttccttg atggtcatgc ctgtgactct tttttatgcc
    39061 aatcagatcc aagcgattcc attagaacaa tttctatccg ttcattcgct gatcgatgaa
    39121 caaggaaccc aaaaattttc tgaacttgaa ttatctgaaa ctgggttaca agcatcgcaa
    39181 caaacgatag ctgtgacccc tgaaattttg gtaggtgtgt ctttatctga gaaacaacaa
    39241 tccgatcatg gaacttttat tgattttgag aaggaacaat gggtgatcca acaaaaggat
    39301 aaatctggta tacgccgcta tacgatgaat tatagcccat ctttccaacc agattctgta
    39361 cgtacgcccg aagatttcca acgattttta gaaagagaat tttatgccag taatcgtcca
    39421 acaatcattt tatcttatag tttaagtctt ggtcttgtcc tatttgtcat gacgagtctc
    39481 attttattcg gggcttcctt tttcttgtgg atgacaagaa aaagccaact ttcatccatt
    39541 catacattca aagagagtgc aaatttgatg ctgaatgtta tgggaatagg ttccatggca
    39601 gcagcagttg tagggtttat ccactttgac tttatcttga tgctaagtgt ccaaacaacg
    39661 ataactgtct tgctgctttt atgggttttt gtcaaaacaa gattcaaaga taagcgtgtc
    39721 gaatgacaag tttaagcgat ttatgcgaca atgaatgtga aaaaaatgaa aaataaagta
    39781 gtttttgaaa aatttctgaa aaaattaaac ttcttagttg attcttttct tttttagtat
    39841 taacgtaata gggtagtttt tttaaggagg aaaatcatgt tagagaaaac tttatacaat
    39901 caattatttt cacgttcttt ctcgctccct gtcgaagtaa attattggga cggtacaacg
    39961 aaacaatacg gagatacgga cactcctccc caaatcaaaa tcaatatcca tgaagaaatc
    40021 ccaatgaaag agattacaag taacgcatct ttggcactag gagaagccta tatggatcat
    40081 cgaatcgaga tcgagggaag tatccaagca ttgatcaacg atgcttatca gcaagcaaac
    40141 agctttttac gaggaaaaga ttatctaaaa tggctgccaa agaaagaaaa acatacgaaa
    40201 caaaaaaaca aagaagatat ccatgcgcat tatgacttag gtaacgactt ttataaactt
    40261 tggctagatc caactttgac ttattcttgt gcttatttca atacacctga agatacgttg
    40321 gaacaagcac aaatcaataa agtccatcat atcttagaca aactctttat caaagaaggc
    40381 gaaacgttgc ttgatatcgg ttgtggctgg ggaacattga tgttcactgc taccaaagag
    40441 tataatgtca aggcaactgg gatcacacta agtgaagaac aatacgattt gattaccaaa
    40501 agaataaaag aagaacattt agaagataaa tgccgtgtat tattaatgga ttaccgcgaa
    40561 ctaaaaggcg aaacgtttga tcatatcaca agtgtaggta tgttcgaaca tgtaggttct
    40621 gaaaatcttg aaggttattt caaagtggta aaagatttat tgaaaccaaa aggaacagct
    40681 ttgatccatg gaatcagccg acaacaaggc ggtgcgacaa atgcttggat caataaatat
    40741 attttccctg gcggttatgt ccctggtgtt actgaattag ttgataatat tacaaaaaac
    40801 gatttgcaac tgattgattt ggaaagctta cgtcgtgact accaattgac attagaacat
    40861 tggacaaaga attttcatca agtccaagat caagtcacga aagaaatggg tgattccttc
    40921 tatcgaatgt gggatctata tttacaagct tgtgcagctt catttgaatc aagtaatatc
    40981 gatgtgattc aatatttgct tgttcaacct ggaaacaatg acatcccaat gcatcgtgca
    41041 taattgaggc aaaagtactg tttaaagact atttaaaaag aagctaagtt ttatgatgct
    41101 ccagaagtga acttttttgt ctaacttcta ggattgtctc taaagcttag ttt
//
LOCUS       DARPZJ010000021        40373 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.021, whole genome shotgun sequence.
ACCESSION   DARPZJ010000021 DARPZJ010000000
VERSION     DARPZJ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.021"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="SLE23_001351"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="SLE23_001351"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEI8468265.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="SLE23_001352"
     CDS             complement(2262..2513)
                     /locus_tag="SLE23_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEI8468266.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="SLE23_001353"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="SLE23_001353"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HEI8468267.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="SLE23_001354"
     CDS             3463..3681
                     /locus_tag="SLE23_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468268.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="SLE23_001355"
     CDS             complement(3970..4482)
                     /locus_tag="SLE23_001355"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEI8468269.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="SLE23_001356"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="SLE23_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEI8468270.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7378)
                     /locus_tag="SLE23_001357"
     CDS             complement(6935..7378)
                     /locus_tag="SLE23_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HEI8468271.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="SLE23_001358"
     CDS             complement(7379..8167)
                     /locus_tag="SLE23_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8468272.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /locus_tag="SLE23_001359"
     CDS             complement(8164..9105)
                     /locus_tag="SLE23_001359"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEI8468273.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="SLE23_001360"
     CDS             complement(9282..9869)
                     /locus_tag="SLE23_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HEI8468274.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="SLE23_001361"
     CDS             complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="SLE23_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEI8468275.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11691..12701
                     /gene="gap"
                     /locus_tag="SLE23_001362"
     CDS             11691..12701
                     /gene="gap"
                     /locus_tag="SLE23_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEI8468276.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12786..13721)
                     /locus_tag="SLE23_001363"
     CDS             complement(12786..13721)
                     /locus_tag="SLE23_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8468277.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13907..14866
                     /locus_tag="SLE23_001364"
     CDS             13907..14866
                     /locus_tag="SLE23_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HEI8468278.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14952..16046)
                     /locus_tag="SLE23_001365"
     CDS             complement(14952..16046)
                     /locus_tag="SLE23_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEI8468279.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16235..16996
                     /locus_tag="SLE23_001366"
     CDS             16235..16996
                     /locus_tag="SLE23_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8468280.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17111..17551)
                     /gene="fabZ"
                     /locus_tag="SLE23_001367"
     CDS             complement(17111..17551)
                     /gene="fabZ"
                     /locus_tag="SLE23_001367"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEI8468281.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            17771..18526
                     /gene="fabI"
                     /locus_tag="SLE23_001368"
     CDS             17771..18526
                     /gene="fabI"
                     /locus_tag="SLE23_001368"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HEI8468282.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(18636..19649)
                     /locus_tag="SLE23_001369"
     CDS             complement(18636..19649)
                     /locus_tag="SLE23_001369"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEI8468283.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            19814..20734
                     /locus_tag="SLE23_001370"
     CDS             19814..20734
                     /locus_tag="SLE23_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEI8468284.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(21014..21514)
                     /locus_tag="SLE23_001371"
     CDS             complement(21014..21514)
                     /locus_tag="SLE23_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8468285.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(21621..22139)
                     /locus_tag="SLE23_001372"
     CDS             complement(21621..22139)
                     /locus_tag="SLE23_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEI8468286.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22140..23495)
                     /gene="rph"
                     /locus_tag="SLE23_001373"
     CDS             complement(22140..23495)
                     /gene="rph"
                     /locus_tag="SLE23_001373"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HEI8468287.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(23498..24319)
                     /gene="racE"
                     /locus_tag="SLE23_001374"
     CDS             complement(23498..24319)
                     /gene="racE"
                     /locus_tag="SLE23_001374"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEI8468288.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(24481..25137)
                     /locus_tag="SLE23_001375"
     CDS             complement(24481..25137)
                     /locus_tag="SLE23_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8468289.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(25153..25800)
                     /locus_tag="SLE23_001376"
     CDS             complement(25153..25800)
                     /locus_tag="SLE23_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8468290.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(25813..26628)
                     /locus_tag="SLE23_001377"
     CDS             complement(25813..26628)
                     /locus_tag="SLE23_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEI8468291.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(26642..27379)
                     /locus_tag="SLE23_001378"
     CDS             complement(26642..27379)
                     /locus_tag="SLE23_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8468292.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            27633..28643
                     /gene="trpS"
                     /locus_tag="SLE23_001379"
     CDS             27633..28643
                     /gene="trpS"
                     /locus_tag="SLE23_001379"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEI8468293.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            complement(28813..31233)
                     /locus_tag="SLE23_001380"
     CDS             complement(28813..31233)
                     /locus_tag="SLE23_001380"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEI8468294.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(31238..32281)
                     /gene="pheS"
                     /locus_tag="SLE23_001381"
     CDS             complement(31238..32281)
                     /gene="pheS"
                     /locus_tag="SLE23_001381"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEI8468295.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            complement(32590..32931)
                     /locus_tag="SLE23_001382"
     CDS             complement(32590..32931)
                     /locus_tag="SLE23_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8468296.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            complement(33000..36722)
                     /gene="addA"
                     /locus_tag="SLE23_001383"
     CDS             complement(33000..36722)
                     /gene="addA"
                     /locus_tag="SLE23_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEI8468297.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            complement(36719..40246)
                     /locus_tag="SLE23_001384"
     CDS             complement(36719..40246)
                     /locus_tag="SLE23_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HEI8468298.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
BASE COUNT        11436 a         8670 c         7046 g        13221 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag cgttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgaa aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgaggat gccgtttcac agcaccccta ataaaggagg aacttttgat atgacagtaa
    11701 aagtaggtat taacggattt gggcgtattg gccgtctggc tttccgccgc atcaaagaag
    11761 tctcagatga tattgaagta gtagcaatca acgacttaac aagtccaact atgttagcac
    11821 aattattgca atttgactct actcatggta cttatcctgg cacagttact gcaacagaag
    11881 actcaatcgt agtggatggc gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa
    11941 tcccttgggc aaaagaaaac ggtgtagata tcgtactaga atgtactggt ttttatacat
    12001 ctgaagaaaa agcaaaagcg catttagatg ctggtgtcaa acgagtagtt atttctgccc
    12061 cagctggtgc tatgaaaacc atcgtctata acgtcaatga tgatacatta gatgaaaacg
    12121 acaaaatcat ctcagcaggt tcatgtacaa caaactgttt agcacctatg gcttatttct
    12181 taaataatga atttgggatc gaagttggta caatgacaac agttcatgcc tacacttcca
    12241 cacaaatgct cttagatgga cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg
    12301 ctgacaatac tatcccacat tctactggtg ctgcgaaagc aatcggctta gttatccctg
    12361 agctacaagg aaaattacaa ggacacgcac aacgtgttcc agtcgttgat ggttcattaa
    12421 ctgaattggt ttcagtattg aaaacaaaag taactgctga tcaagtaaac gaagcaatca
    12481 aaaaacacac agttgacaat ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg
    12541 atgtcattgg aacaactcaa ggttcgatct ttgacccaac gcaaacagaa gtaacaactg
    12601 ctggtgattt ccaacttgtt aaaactgttg catggtatga caatgagtat ggatttactt
    12661 gccaaatgat tcgcttacta gaaaaattcg ctaacttgta atttgataga tcaatcgata
    12721 aaagaagcct ttgactggat ccagtcaaag gcttctttct tttcatcccc tacttttaaa
    12781 ctcgttcaat gaacatattg gcttaaaaat tgttggacta cttgctgata tttttcagga
    12841 tctgtcttgt atgcttccgc atgctcggct ccttttacaa catacttttc ttttggtccc
    12901 ttcgttgcac gatagacctt atctaacatt tcaaatggta caaatgtatc ttcgtctcca
    12961 tgtataaaga gcattgggcg ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg
    13021 aaaaagtagc cagcacggac ttttgtcact agactcgtta cttgcataag cggaaatgct
    13081 ggaagactaa acatatcgtc tagctgataa gcaagctcat catgaacgga agaataaccg
    13141 caatcttcaa tgattgcttt cacattatct ggtagttttt ctccgctagt catcataact
    13201 gttgctgctc ccatgctgac accgtataga acgatttctt gcgattttcc attgttttct
    13261 agcactttgt ttatccactg tacatagtct ttacgctctg gccatccaaa tccaatgtaa
    13321 tccccttcgc tttttccatg tcctcttgca tcaggaacaa ggacattgta acccatatca
    13381 tgaaacatct ttgcgtaatt ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca
    13441 agagctgttt tttcactttt cgtttcagca ggaagataaa tcgctgataa tttcagaccg
    13501 tcttttgaag tgatggtcca atcgcttcgg ttttcttttg aactaaacca tttatgtgca
    13561 tccgtttctt tggatgtctg tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca
    13621 gaaggcacaa cagcataatt ataaaaataa ttccctgcaa acactaacgc aacaatcaga
    13681 gctaaagcga cgcctaaaag gattttcatc caaagtttca taaatcatcc atctcatttc
    13741 tcttttttca tataaccttg aattagtata atcaaagaat ctctactatg caatgttcat
    13801 ttttataacc cgcgaattgt aaaattaagt tagaaaaata aaaaggcatt tatggtacac
    13861 tcaaattgta tttccgacga aagaaaacaa aggagtgtaa ccataaatga cctacaaaca
    13921 tcttaccata gacgaactga caatgataga atcatattat cttcaacata ataagccggt
    13981 tgaaatcgct aaccgaatgg gacgtgctat acaaactatt tataatgtag tcaataagtt
    14041 caagcaaggc aagactgctc ttgattattg gcaccagtat aaagaaaata agaaaaaatg
    14101 tggtagaaaa gtcattcaat tacctgctca tgaagtagat tacattaaag agaaagtcac
    14161 tcttggttgg acgcctgacg tcattatcgg gcgaaaagaa aggtctgttt catgcggtat
    14221 gagaacactt tatcgtttat tttctaaagg aatatttgat attgacacac taccgatgaa
    14281 aggtaaaaga aaacccaatg gccatcagga aaaacgggga aaacaacagt atcagcgctc
    14341 aatccatgat cgacctgata attatcctga tttcaattct gagtttggtc accttgaagg
    14401 tgatacgatc gttggcattc atcataaaag tgccgtcatt actttagttg aaagattatc
    14461 taaagtcatt atcacgatta aacccaacgg ccgtaaggca ttagatattg aaactgccct
    14521 taatcaatgg ttttctcgct tccctaaaaa cttctttaaa tctattacgt ttgactgtgg
    14581 aaaagaattt tctaactgga aagccattag taaccaacat gatattgata tatattttgc
    14641 ggaccctgga acaccttctc aacgcccatt aaacgagaat tctaacggga ttctgcgtcg
    14701 taatggactg ccgaaatcaa tggattttag aaaagtgaat cagacattta tttccagtgt
    14761 cagcaatcaa cgtaatcata ttccaagaaa atcattgaat tacagaacac caatcgaaat
    14821 atttttgagc tatgtacaag aagcatttta ttctagctta atttgacaaa tcataaccta
    14881 taaaaaaaca aaataaaaaa gcagaaataa ctggctattt ctagcggatt atttctgcaa
    14941 taactaatta tctatttttt attttcaatt aatttaaagc ttgaccatgg tttcaaaaag
    15001 tcaaggagga ataattcgtc atcggagatt cttcctacaa cattgacacg tccgtcgttt
    15061 ttcatatcct tcaaggcgat ttgtgtttct cctttgtatt gaccgtaccc ttcattgtca
    15121 atcagtacat ccccatgatg catatctcgc gtattatgag gcgggaaatc tttatctttg
    15181 tagtatacac gagtcatcgt tgaacgaagg atatattctg agcgatcccc tcgataacta
    15241 tgaaggttat caaacaagca gattcgttcg ttttctgtaa taccttcttc cgtatctact
    15301 ttcaatgttg gataatccgc gttaaatgct tctgccattt ctttcaattc ttcttcactt
    15361 gcgtacgcat ttccaataga aatatcatca atcaatcctg taaggattaa atgcttcact
    15421 tgtgtcgcaa tttcaagatc tcggtggtct tccagcgtgc acaagccatc ttgcgtaggc
    15481 caagggccaa actcagcaga ttgcgaattg acgaatgcca tcgtattcaa attatatttt
    15541 ctgaattttt ctgaacaaaa aacaaagtgt tcgtatccta aaccagagta tcgatgagga
    15601 taaaaattat gagaacctaa taaattatcc gtgtttggcg aataactcat gatgttgtca
    15661 acgtaattcg tgcccgaact catattgatc tcgattttga taccaaaagg attgcgcgtc
    15721 atttttgctt cttctgctcc tgtgaatccg atatctaagc ggaccccgta ggcacccatc
    15781 ttatggaaaa aagataagtc atcgtaagaa atctccaact gttcaaataa cgctggattg
    15841 atatcaacca ttacttccat gcctaggcta ttcgcgtaat caactacttc tttaaattct
    15901 gaaagaactt tttctttatc atcattgatc tgcagcaaac tggtaaaaac ccgtttatac
    15961 ccatacttat gagctaaatc caagtacgct ttgtcctttt caaatgttga ccgttctgga
    16021 taaatcgaga ttcctaattt tcccatatta ccatttcctc ctgcatcttt tcgtttttgt
    16081 atccacttac attatagcaa acacaaagta aatggtctac accttttctt tttcttttaa
    16141 aataaatgat aaattccaat aatttaagta ggtattttcc ctctattttg ttatcattaa
    16201 agataacaaa atagtaaatt ggaaaggaac agttatgaag aaaaataaag ttattttaag
    16261 tattagttta gcagcagcat tgctgtttgc tgctggttgt tctgcaaaca acacgacttc
    16321 ttctagttcg tctacagaaa gttcaaaaag tacatctact gcggaaagca cgactgccag
    16381 tagcgtcgat ttgaacgcat tggaattacc acaattgacg aaagatgtcg ccgaaaatga
    16441 agatctggtc gaaatggtga cgaataaagg cacaatcaaa atcaaattat ttcccgaaca
    16501 cgcaccaaaa gcggttgaaa actttatgac acatgcaaaa gacggttact ataacggact
    16561 gactttccat cgcgtcatca aagatttcat gatccaaggt ggcgatccta aaggcgatgg
    16621 cactggaggg gaaagcattt ggggagaagg atttgaaaca gagatcaaca accaccttta
    16681 taatataaga ggtgcgttat ctatggctcg ctcacaagat cctaacagta acggcagcca
    16741 gttctttatc gttcaaaata cagatgatat gcatgatggt cttttaaaag acgactatcc
    16801 tcaagcaatc atcgacgctt ataaaaacgg cggttatcct tcactagatg gccattatac
    16861 tgtcttcggc caagtgattg aaggaatgga tgtcgtggat gctattgcaa atatcgaaac
    16921 agatagttca gacaaaccaa aagaagaagt aaaaatcgat aaaatcaata tactgcaaga
    16981 agcaaaacaa aaataaaaaa ataacgtctg aatcctgcat agatgacaac gtatgctagg
    17041 attcaggcgt cttcttttta cataaaaagc aagtaagctt ccttttgttt tgctatatca
    17101 ggttttatag tcaagcattt tggttgacga tgaacgtgaa ctcgcactca cagacttttt
    17161 tatcatctac atatgctgca gataacgctg taccgactga tcccttcatt ttggtgattt
    17221 caaaatgaca tttcagcaca tctcctggaa caactttttg acggaatttg gccttattga
    17281 tcccaccgat ataagctctt tttcctagaa actcttctga ttttaggata agtatcgaac
    17341 ctgcttgtgc cagtgtttct agaatcaacg cacccggcat cactggattg tcaggaaagt
    17401 gaccttggaa aaaatcttca ttgattgtta cattttttgt cgcaacgatc ttttttcctg
    17461 gttctaaagt atctacataa tcaatataac aaataggata acgattagga atcaattcca
    17521 ttacttcagt agcagataat acgtaagaca taattaaact ccttctttca ggcaattgcc
    17581 attttcatta ctttgactat caaagtatca tattcctaaa tatttagcaa tcttttttta
    17641 atttaagaaa aaatagtttg acaatcaaaa cattttgact aataattaag aaatcaagaa
    17701 gttattttag ctattattct ctattttttt acgactatca aatttttatc agaaacaaag
    17761 gagagtcatt atgtcatttc tagaaggaaa aaaaatcgtc attatgggcg tcgctaacaa
    17821 aaaaagcatt gcttggggtt gtgctgaagc aatgttgaaa caaggggcag aaattatcta
    17881 tacttaccaa aatgaacgaa tgaaaaaatc attagtcaaa ttggtcggcg aagaagcatt
    17941 cactgtagaa tgtgatgttt ctagcgacga aagcatcgaa aaagcaatga atgccatcgg
    18001 tgaatatgct ggggagatcc acggccttgt ccatgcagtt gcttacgcca acaaagaaga
    18061 attgtccgga aatgtgtctg atatttccag agacggctat caattagctc aagatatcag
    18121 cagctactct ttaattgctg tatcaaaata cgcacaaccg tttcttgcac caaacagcgg
    18181 gatcgttagc atgacttatc taggttcaga acgcgcaatc ccgaattata acatgatggg
    18241 tattgcgaaa gcttctcttg aagctgctat ccgttatttg gcagctgagt tctcgcctaa
    18301 aggaattcgg gtcaatggaa tctcagctgg ggcaatcaaa acattagctg tcacaggtgt
    18361 taaagactat caaaaactga tccagttatc tgaatctcgt acgcctgatc agcaaggtgt
    18421 gacgatcgaa gaagtcggta atgcttgtgc tttcttaatc agcccacttt ccagcggaat
    18481 catcggtgat attatctacg ttgacaaagg tgtccatctt tcataaactt ttgttgcatt
    18541 ctttaaagta aaacatataa aaatcaggaa aaaacttttt aaagtctctt cctgattttt
    18601 tctttttacg tttttttcaa ctcattactt tgaaattatt ccacgacttc aatccagcct
    18661 tctggtgctt ctatgtctcc aaattgaata cctgtcaatt catcatacaa ccgttttgtt
    18721 actggtccta cttccgtttc actataaaat acatgaagat tgttattgtg ataaatccca
    18781 ccgattggag aaataacagc cgctgtacca catgcaccag cttctgcaaa ttgatctaga
    18841 tcatcaatga aaatatctcc ttcaattgct tgcagtccta gtcgttcttc agctaactgc
    18901 aacaaggaat atttcgtgat acttggtaag atagagggcg attgcggagt gatgaatttt
    18961 ccgtcttttg taattccaaa gaaatttgct gcacctactt cttcgatttt cgtatgtgtg
    19021 gctggatcaa gataaacaca atctgagtaa tccagttctt ttgcttctgt tcctggaagt
    19081 aaactcgctg cgtaatttcc gccgactttt gctgcaccag tccccttagg agcagcacga
    19141 tcgtaatcag atacaataaa attcgttggt tttagtccac ctttgaaata cgctcctact
    19201 ggcgtacaga agacgacaaa taaatattct ggagctggat ggacaccaat gttttcaccg
    19261 accccaatca gtaaagggcg caagtataat gtagcgcctg ttccataggg cggcacaaaa
    19321 tcttcatttg cttttaccac ttgcttgaca gcatcaacga acatcttttc agggaccatt
    19381 ggcatcagca atcgtctagc actttgattc atccgtcgac tattttgttc aggtcgaaag
    19441 agattgacct tgccgtcttt tcgacgataa gcttttagac cttcaaaaca ttgctgacca
    19501 taatgaagcg ctggagagcc ttcatgaatc gtcaggtaat tatcttctgt caattctcct
    19561 tcttcccatt gtccgtcttt ccatttggca ataaaacgcc aaggagtttt gatataagaa
    19621 aaacctagat tgttccaatc gatttgcata tacttaccac cttcgttatt ttctccacat
    19681 tttatcatta tccatattat ttgtcatttt attttcagct tttttccttc attatagtta
    19741 tttttgctat ttcctttttt gaaaacttct tggtacaata cagaaagaat caaattttag
    19801 aaaagaggat tttatgtttt cattattagc aactgccggt acgacagact cttctggcga
    19861 gacattgaca gatcaagctg tcagcaaagt aaatgcgttt cagcggtttt gggacgggat
    19921 tgattgggac gccattttgg ctgcctttat ccaaaaaagt ttatatctga tttttttgat
    19981 cgtccttttt tggattcttc accgtgtggg aaaatatctg attgataagt cttttaatca
    20041 gtattctaaa aaagccattc taaacgagag ccgcttaaag actttacata gtcttttaaa
    20101 tactattttt cattataccc ttggtttctt ttttatctat gcaattttat ctgctatcgg
    20161 tgtgccgatc ggatcacttt tggctggtgc cggaattgca ggtgtggcaa tcggtcttgg
    20221 tgcccaaggg ttcatgagtg atgttattac cggatttttt attatcatgg aacaacagat
    20281 ggatgttggg gactacatca agctagcaaa cttaacgatt gaaggaaccg tcgtatctgt
    20341 tggtatccgt acccttcagc tgaaagcaac ggatggtact gtccatttca tcccgaatcg
    20401 aaacatcacc acgatcagca atctctctcg tgcaaatatg caagtacttt tagatattcg
    20461 gattgttcct gaagaaggat atgacaaaat ctatgagatc attgatcgag taaatcgtac
    20521 attagctgaa aaataccaag aagagctcca aactgaacct tctatctttg gattagtgga
    20581 tcttggaaac agcaattttg cgattcgtac ggtctgctac gcattgaacg gaaaacaata
    20641 tgccttaaaa gaagagttct tgagctccta tgtcaaagaa ttgacagctt ctggtttcac
    20701 gattccgaac agtccaattg ctgtcggaaa ataatttgga caaacgatgc aacgaatctc
    20761 actaaaaaga gcgtgggaca aaagtaaaga acacttttgt cccacgctct aaacacgtat
    20821 aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttgaaa
    20881 agcaattttc gtgaattcct tcttatttct tggagttaaa cgcttttgtc ccagcctctt
    20941 tttcaagata aagtcaaaac tggtacgctg ttttttctac ttattttttg attatctttt
    21001 agtttctcgt tctttagctc acgatatcga tttgttcttt taattcttcg attttcggag
    21061 acaatatatt acgacgttct aattcatgca ccatgaagtt tacggcttta agcagctctt
    21121 ttcttgtaat gattcctttg aaaatccgat cttctgtgac aaccggtaaa aaaggcgaat
    21181 cgactaacaa atggagtact tcttctagtt cccaattttc atcaattgtc ggaacatctg
    21241 tttctgtcac atcagcaacc gttagtcctt ctaacgggtc catgctgatt gtttgcaagt
    21301 caatcatttt attgaccaca tctgataaac ttactagtcc tacaaagtga tcatcttttc
    21361 ctaatacagg aattttggaa taaccgacct tcgataacac aagtaaacca tgggacaatg
    21421 gatgatgata cataacattt gccacatttt ctgcaggaat caaaaacgtt tcctgatttt
    21481 ccagcagcat ttctcttact ataggtccaa tcatctgatg gcctccattt ctatttcatt
    21541 caacactact attttaccga aaccggatgc aaaattcata aaataaagct tatttttatt
    21601 aaaaattaga gtttttttat tcagcgctct ctcgaaaaag aaaaggccaa ctcttcaact
    21661 gcctgatggg cacggttata gtattgaaca gaaatttggt catctaaact ttcgataaga
    21721 gcatatgatg ggatttggat cgggcctcta ggctgagaaa tgctaccagg attcaaaaac
    21781 aggattttct gatccatctc acagcctatt tgatgggtat gaccaaaaaa caccatatcg
    21841 gcagttgcag ctcgagcttc gattgctaac tgtgtcaaac caaatcggac attcgataaa
    21901 tgaccgtgag tcatgaatac tgtatcctga ccagtttgga tcactttttt ctgttcgaat
    21961 cctggtccat aatcacaatt accttgaacc acttggaatg tatcccataa tgggtcagaa
    22021 gcttctaatt ccgaatcacc acaatggaaa aagatatcca cttcagaacg ataacgatct
    22081 actaagtcaa cgaggatatc tctgtctcca tgattatcac ttactactaa ataccgcatc
    22141 tatctctctc cttccagcca ttgtttccac tcggcactca attttttcat tgcttgagcc
    22201 cgatgactga tcttgttttt ttcttcgctc gataattctg ctgctgtttg tttcttacct
    22261 tctgggataa ataaaggatc atacccaaag ccattttcgc cagatggtat acgggctact
    22321 cgaccgggcc attccgcttc tactacaagg ctgtcttttt tgggtgccgc gaatactaac
    22381 gtacaatgga attgtgctgt tcttttttca tccggcacat ctgtcaattc atataataat
    22441 ttggcgttat tccccgcatc acttttttgt tcccctgcaa aacgtgcaga atagattcct
    22501 ggcataccgc ctaaagcatc cactttcaaa cctgaatcat ctgctaagac tggctgatca
    22561 agcaattgtg caatcgtttc tgcttttaat cgggcatttt cttcaaatgt gctgccagtt
    22621 tcttccacat ctggcaattc aggatagtca agtaatgttt ttacatgata tcccgcttct
    22681 ttgaacatat ttcgaaactc ttctgctttt cctggatttc ttgtcgcaat gatgattgtt
    22741 tttgtttctt ctatccgctc atcattttga gcaaactctg ttagcaaagc atgtttttgc
    22801 tctttgatca aatcttcaat cgcgtttttt ccaaaaaaga gcatttcatt caactgttca
    22861 ccatcaaacg ttgcttcttc tccagttcct tgaatctcca cgaattttcc agattctgtc
    22921 attacaagat tcatgtctac aagtgctgcg gaatcttctt ggtaatccaa atctgtgacg
    22981 caagtcccat ctggtaagat tcctacgcta actgcagcaa gatgttcttt tattggatct
    23041 tctgacaatt ctttttctct taaaagtttt tcaatggcta atttcaatgc cacaaatgcc
    23101 ccagtgatac ttgctgttct agtaccgcca tccgcttgga tcacatcgca gtctacgatg
    23161 atactacgtt ctcctaattt ttccaagtct actactgcac gcaaggaacg accaataaga
    23221 cgctggattt ccattgttct accagaaagt ttccctttgc tgctttctct acgatttctc
    23281 gtactcgttg ctcgaggcag catactatat tctgctgtca cccatcctgt tcctgtttct
    23341 ctcaaaaaag ggggaacaga attttctatt gttgcagaac aaataactgt tgtatcacca
    23401 aaacggatca ctaccgatcc ttctggatat ttgaaaacat ttgtttgaag ctccagtttg
    23461 cgaagctctt gggcttttct cccgtcatga cgcatcctta ttttcctccc aattcgatat
    23521 gttctacatt taagtgtccg attccaagcc agtcttcagc tatttcctcg aaaagtttgg
    23581 cagagccagt tgtataaaac tggcataatg tccgaccatt ttgcggtgaa ttgctcaaat
    23641 tgaaataatc taacagcata gatacttcac ctactgtttc tgctccagaa tcgatcagtt
    23701 gaacattttc tcccattaca ttttgaatga tggggcgtaa taatggataa tgggtgcatc
    23761 ccaaaatcaa tgtatcgatt tttttagtgg ttaaaggagc taatgtttct gccacaattt
    23821 ttttcgccac cgatgaatgg tattcattac tttcgacaac tgaaacaaat ttgggacaag
    23881 caagacttgt cacagtcaat tctggtactt tctctttcag tgctttttca taagcttgac
    23941 tttttaccgt accaatcgta ccgataatgc caacttgttt attttgtgtt ttttttactg
    24001 ccgctctagt accgggaagg atcacaccga tgactggaat agaaagagca gctttgattt
    24061 cttctaaagc caccgcagtt gcggtattgc aggcgatcac cagcatcttg attccttgct
    24121 ccaccagata atccgtcatt tcccaagtat actggattac ctgttccgcg ggtctagggc
    24181 catatgggca gcgtgctgtg tctcctacaa ataaaatatt ttcattcggt aattgtttca
    24241 gggcttcttt tactacagtc aagccgccga cacctgaatc aataaatccg atagggcgat
    24301 tatctgtcaa tcgtatcatc ctttttttca ataaattcta tcctccctat tgtgtacttt
    24361 ttagcgtgaa ttttcaagtg ctcttacttg cttaaaacaa tcgaaatctc tttttttcga
    24421 atggaaagag gaaaagcggt tgtgacttta gtttgccaca accgctaaaa gaatcatcta
    24481 ttaataactg taccgtctct tttccaagta accggaaagc agagaaagcg cgtaacatac
    24541 cacgaagtac ataagtgtca tgatgatgaa catcggaagc acataattgg tgttctgtcc
    24601 ataaataata cgtgcctgat gagaaagttc aggtaaagaa atgattactg ctaatgaagt
    24661 atctttgatc agtgaaatca attggctcac aattgccggg atcattgatt taaatgcttg
    24721 cggtaacacg atcgttcgca tcgattctac ataagtcagt cccgttgata atcctgcttc
    24781 catctgtcct tttggaacag cattgagtcc agctcggaaa atttccgaca acatagctga
    24841 ctcaaaaatc gttaatgctg cgacagcgga ccagaagatg ttcatctgaa tgccgatttg
    24901 aggtaaggca aagtaagtga agaaaatgat caataataat ggaagattcc gtataatatc
    24961 aatcactaca ccaaggattt tggaaaagaa agggatattc gcaaaacgaa tcacacctgt
    25021 cagaccaccg atcaagaaac taaaaatgat cgaaaacaat gaaacttcaa cagtaacctt
    25081 taatccttcc aataaaaaac ggatattcat ccatgaaaaa gcgccgctaa aatccatgta
    25141 tttcccctcc ttctatgaac gaaccgccca ttttttctca agataaacca ttaagtaaga
    25201 taacggtagc gtgataacta agtaaaataa cccaacgatg atatacgtat cgaaggtatt
    25261 gaatgtttca ctagcgatca agtctccttg atacatcaaa tctaaaccag ctacgattgc
    25321 taaaatagat gagtttttta cgaggttgat aaattggttg cctaatggcg ggataacgat
    25381 tttgaatgct tgcggtaaaa caatataacg catgatttct gaataggtaa aaccagaaga
    25441 tagtcctgct tctgtttgac cttttggtac ggtttgaatc cctgaacgta ctgtttcagc
    25501 aataaaagca gatgtataga tcgttaatcc aatcgtacct gcttggaatc catctagatt
    25561 aaaccaataa atcggtacga caacataaaa aaacatcacg atgattaata atggaatgtt
    25621 tctaaaaaat tctacatatg cctttgctaa ggcgctcact actttattct ttgataattg
    25681 gaagattgcc attaacgttc cgataatcaa actaaacaca agtgctaaga cactcgaaaa
    25741 caatgtgatc ttgaacccgt cgacaaagat tggtccataa gtttgtatca attcgctcat
    25801 tgcctctccc ccttactcta cttttccttc agtttcattt ggaaaccatt tttgatagat
    25861 tttatcgtat gtgccatctg catgcatttc ctctagcgct tggttaacag ctttcaagaa
    25921 gttttcttgc cctttgttga tcgcaatccc gtaaggctca ttagtaaacg ttccaccaac
    25981 taactcatac tctggatttt catctgcaat ccctaacaaa atcgcattat ccgtagtcat
    26041 cgcgtctccc tgaccagatt gtaaagcagt aaatgcttct gcatagtttt ctaattctaa
    26101 aatttttgca tctggtgcat gctgtcggat attcgcagcc gatgtagaac ctttgactgc
    26161 tagaaccgtt gtagaagcat tcaaatcatc tacacttttg atttggcttc ctttctttac
    26221 caacaaagct tggccagcat cgaaatagac atctgaaaag tcaacctgtt tttttcgttc
    26281 atctgtgatc gtcatcgttg caataattgc atcgatattt ccgtttttca ataatggaat
    26341 ccgagtttta gaagtgactt caacaaattc tgtttttcca ttgtcaccaa ggatcttttt
    26401 agtgattgct tttgcaatat ctacatcaaa tccttgtaca gttctgctct caatatccat
    26461 cattccaaat aatcgagtat catacttgac accccagatg atttcattgg tagatttgct
    26521 tcgctctaaa atatcttcat ttgccaaccc atttccttta catccggcta gtgcaagaaa
    26581 agcaatgcct aaaaggaaaa tcaggcgtat tttttttaac ctgcgcatct ttttcctcct
    26641 atcaatgatt gataacttta ctgataaatt gctgtgctcg gacttcattt ggattttcga
    26701 aaaagtctct cacatttctg ctgtcttcca atacttctcc atcagccatg aagataacac
    26761 gatccgccac ttctttggca aagcccattt catgtgtcac gacaatcatt gacataccgt
    26821 catgagccaa ttttttcata acgtctaata catcaccaat catttccgga tccaaagcag
    26881 aagtaggttc atcaaacagc agcatctcag gattcatcgc taaacctctg gcgattgcca
    26941 cccgttgctg ttgtcccccg gataacatgg aaggataaga atctttctta tctaacatat
    27001 tgacagtttt caaaaatttc tccgcgtttt tgactgcagt tgcctggtct tgcttcaaca
    27061 ctttgattgg tgctaatttg atgttttcca gaacagtttt atttgggtac aaattgaaat
    27121 gttggaaaac catgccgatg ttttttcgga cttctgtcag ttttgtcttt ttatcatgca
    27181 agtcagtatc attaatcagc agcttacctg aagagatcgt ctctaatcca ttgatacagc
    27241 gaagcatcgt gctctttcct gaaccagaag gaccaatgac aacgacaact tctcctttct
    27301 cgaattcgag attgatattt tttaatgcgt ggaacttgcc ataatattta tccacgtgat
    27361 caaatttaat cattgccata gaattacact cccattatta tttagtaaga tttcttttaa
    27421 agatgtataa taaaatacat tatatctgat agtttagtaa tttgtaaagt ttcttagaac
    27481 gtttattctc ccataaatat ttcttccatt tctaatctat tagttatttt atcctctttc
    27541 cttgtttttt ccttaggaac tgttgtttct tttcaggaaa aacggtaaga tattaagtgc
    27601 tcagacttac aaatcgtaaa gaggtgtctt ttttgaaaaa tattatttta acgggagatc
    27661 gaccaactgg gaagctgcat ttagggcatt acgtcggttc tctaaaaacc cgagtggcta
    27721 tgcaggcaga tgaagacaac caactgtttg tcatgattgc tgacatgcaa gcactgacag
    27781 ataatgctaa aaatcctgag aaggtttcat caaatgtctt gcaagttgct ttagactatt
    27841 tagccgtggg attagatcct gcaaaatcta ctttatttat ccaatcacaa attccggaat
    27901 tagctgaatt aaccatgtat tatttgaact tagtcagcgt aggacgcgtt cggcgcaatc
    27961 cgactgtcaa aacagaaatc gaacaaaaaa aattcggtga aagcgtgcct acaggattct
    28021 ttatctatcc tgtttctcaa gcagcagata tcactgcatt caaagcgaat cttgtacctg
    28081 ttggtgagga tcaaaaacca atgctagagc agacacagga aatcgtacaa agcttcaatc
    28141 atacatatgg tgaagtcttg gtggaaccaa aaggcgtatt cccaccaaaa ggaatgggta
    28201 gattacctgg aatcgatgga aatggcaaaa tgagtaaatc gttaggaaac ggtatttata
    28261 tctccgatcc tgccgatgtc ttacagaaaa aagtcatgag tatgtatact gatccaaacc
    28321 acatccatgt acaagatcct ggacaagtag aagggaatat ggtcttcacc tacttggatg
    28381 tattcggaac agataaagaa gcaattgaag aaatgaaagc tcattaccgc cgcggcggac
    28441 ttggtgatgt aaagatcaaa cgatacctca ttgatgtatt ggaagctgaa tttgcaccga
    28501 tccgtgcgcg ccgagaagaa ttggaaaaag atccttcagc tgttatggaa atcttacgta
    28561 aaggtagtga agaagctgct aaagtagctg cacaaacact ttctgaagta aaatcagcaa
    28621 tgggaatcaa ttacttccat taattcattt actctaaaaa agcaggctgt aaaggcctgt
    28681 ttttttatct cgtctctgtg ctattccttt tttaaaatca aaaaaagaga tgtgacgaag
    28741 ttgtgtcaca tctttttttc aaatgtatgg tcttcaaaag ctacttgatc gttacttact
    28801 atattttcct tcttagcgaa tacttgcctc taggttttct accaacgctt tttcgacttt
    28861 ttccattgct ttattgattt cttcatctgt caatgttgct tctgggttga cgaatgtcag
    28921 gctatacgcc atggatttat gtcctttttc aatgttttct ccttgataga catcaaataa
    28981 ttggatatct gttaaaaatc ttccggcagc agaacggata acttctgtta attcctgatt
    29041 tgtcacagtt tcttttacaa gcaaagcgat gtcccggctg actgctggga attttgtcac
    29101 tgcttcgaaa acgatccctt tttgagcagc ttccactata gcagataaat caaactcagc
    29161 aacatatgtt tctggaatat cataactttt tgtaatcgtt ggatgcactt gaccgacaaa
    29221 accaataaat ttttcgccaa ggtaaatcgc agcagttctt ccaggatgca tttccttcat
    29281 ttctgtcact gtttgataat ggacatcttc agtgatgcct agttgttcaa ataagttttc
    29341 taaaagaccc ttgatggtga aaaagtctac attttgagct ttcgtctgcc aatctttttc
    29401 ttcccaaata ccagaaatag cgattgctgc atgttttact tcttgcggca gatgtgtacg
    29461 tggatcattt tcttggaaga acacccgacc aatttcatat aaagcaatct ctgtattttt
    29521 tcgggcagtg ttataactga tatcatctaa tagtccgctg atcaaattca ttcgtaatac
    29581 agaacgttct tcgctcattg gccagtccaa acgtgtaata ttactttcat ttataacaaa
    29641 ctgtcttgat ttttcttctg ttgtcaatgc ataactgatt gcttcgctca atccgcttcc
    29701 ttcaaagatt gtacgaattt tacgagtagt ttcttgttct tttgacaagc ttccagcaac
    29761 cgtttctcca cttggaagtg tagatggcaa ctggtcgtat ccataaatac gagcaacttc
    29821 ttcgataata tctgcttcga tttggatatc ccagcgtctt ggtggtacta ctacggaata
    29881 aacatactcc ttttcttcat agctaaatcc aagtgcttca aaaatctcat ttacttcttt
    29941 aacgacaaga gatgttccta aatattgatt gatgcgttca agtgaaatct tcactgatac
    30001 gtcttctgct ttgatctctg agcctttgac cgcgccttgt agaacttccc cacccgcaag
    30061 agaaacgatc attgctgcag caacctcact ggcttctcca acagtcgcat ggttgattcc
    30121 tttttcaaaa cgtgcagagg attcactacg caaattaaat tgttttgctg tacgacgaat
    30181 cgaaattgga tcaaataaag cagattctag tgcaactgtt gttgtttcat tcgtgatctc
    30241 tgagtctaac cctcccatga caccagctaa agcaactggt tctttgccgt tagtaatgac
    30301 gagattgtca gttgtcaatt cccgagattc tccatctagt gttactaatg tttcattttc
    30361 ttttgcacgg cggacaaaga tctcttttga tttcaatttg tcgtagtcaa atgcatgtag
    30421 tggttgtccg aataaaagca aaatatagtt cgtcacatct actacattgt tgattggacg
    30481 aatgccttcg ttcatcaaaa gattttgcag ccattgagga cttggctgga ttcttactcc
    30541 ttcaatgatt ctgatttgat aagcaggaac tgcttcttta tcttcaactt ccacttgaat
    30601 tttatcgcta gcaggacgtg aggattctac cagcttttcg tcatcgaatg taggagtctg
    30661 acgataaatt gccccaactt cataagctac gccacgcatt gacaatgcat ccgcacgatt
    30721 cggtgtgata gataattcaa taatcgaatc atccatatcc aaataaggaa aaactggatc
    30781 gccatttaca gcttcttgtg gcatataata gataccttca gcgtattctt tcggtataac
    30841 actatctgaa tagccaattt cttgtaatga gcaaatcatg ccatttgata cttggccacg
    30901 catttttcct tttttgattt ttacattacc agcgatacgt gagttaggaa gtgcaacaat
    30961 cactttgatt ccaaccttca cattaggcgc tccacaaacg atttgagaca gttcgtcttc
    31021 gccaatatcg acttgacaaa tagaaaggtg atcagaatct ggatgtggta cgcattcctt
    31081 gacttcaccg acaacgattt ttttcaagcc ttcttctgga accgttactc cctctacttc
    31141 gattcctgtc acagacatct tatccgctaa ttcttttggt gttacattcg ataaatctac
    31201 ataacgattg agccatttat atgaaactaa cattttctta ctcccccttg aactgactta
    31261 agaaacgtaa gtcattttga tagaaattac ggatatcatt cactccatac cgcaacatag
    31321 ctacgcggtc tggtccaagg ccgaaagcaa agcctgaata ttcttctgga tcgattcctg
    31381 acatcttcaa cacattcggg tgtaccatgc cagctcctaa aatttcgatc catccagtgt
    31441 atttacatac gttacaaccg gcaccaccac atttgaaaca gctgacatct acttctactg
    31501 atggttccgt aaatgggaaa taacttggac gcaaacgaat ttcacgatct tccccaaaca
    31561 tttttttcat tacgacttct aatgttcctt taaggtcgcc cattgtgatg tttttatcaa
    31621 caactagccc ttcaatttga tggaactgat gactgtgggt cgcatcatct gtatctctgc
    31681 ggaagacttt ccctggcgag atcattcgta gagcaccctt agagaaatca tgtttttcca
    31741 ttgtccgtgc ttggactggt gaagtatgtg tccgaatcaa tatctcgtct gaaatataga
    31801 aagtatcttg catgtccctt gctggatgat cttttggcag attcatccgt tcgaaattgt
    31861 aatgatcaga ttctacttca tatccttcta cgatctgata gcccataccc acaaaaatat
    31921 cttcaatttc ttccatgatt tgtgtcacga tatgacgtgt accatgtttt acttttctac
    31981 caggtagtgt cacgtctatt gtttcttttg ccaaagctgc atttaacgct tcttcttcta
    32041 atacttgttt ttttcgctcg atctcttctg tcaaaagatc tcggatctca tttgcgaaac
    32101 ttccgacttt tggtcgctct tctggactta gatctttcat cccacgtaat acttctgtga
    32161 tcggtccttt ttttcctaac gtttcaacac gtatttgatt taattcattt aaatcttgtg
    32221 ccgctgtgat tttgacgagc gttgcttctt tcaagctctc taattgtgct tgtagagaca
    32281 tgtgcttgtt cctcctttaa attccaaata caaaacaaaa agacctcatt cctgttaagg
    32341 aacgaggtct tcgcgttacc atcctaattt gcggataaat gacttacacc gcactcttac
    32401 ttcgttaacg acaattgccg gtctgatttt atcagacgaa ctcggaaagt gaacttcatt
    32461 tttcaaacac aggatctgct ttcagtctgc gacagatctc cctgaactgg tttagccaaa
    32521 ctactctttt tcgtcatcgt tctttactta ttcgtatgga ctatagttta caagattttt
    32581 tttacaaaat caaccgcatt cttcctctgt gatccatttt tcgctccaaa cttgtatttg
    32641 acgcatcgct ttttgcaagt ctgctccttt ttcagtcaag agatattctg aacggctctt
    32701 ttcgctacag gcaaagtttc gagtgactat tccttctttt tctaattcct tcaagcgttc
    32761 gactaatact cgatcactga ccatcgggat ttttgccgca agctcaacaa agcgttgcgg
    32821 accgttttcg agtagtacat cgataatcaa tccgttccat ttttttccta aaatagagaa
    32881 tgttttttca aatttagggc ataaaacgaa ttctgtctgt gttagctcca tcatactcac
    32941 ctcttcccag agtatagcat aatccttaca aaacataagt caagtttgct caattataat
    33001 tatttgttaa tgtttataat ttgtttcact cgaagcaaaa ttaggaaaac attttctact
    33061 ggcttattca aagcttctga cattgcttgt tggtaaagtc ttagctgtcc ttgatatttt
    33121 tggacgattg catctatttc tgctggatca tccggatgta aaataaaatc tgttttaaaa
    33181 tcatagatat tgagatgatc tttttcttct aggtatccat cgacgattcc gtggattaat
    33241 agttcatctt cttgatttgg atagtcttga aatacttcgt cagcaggaag cagcatggaa
    33301 aaaggttgtt ctcgttttac gttttctttg ttggcaatca gctgttgacc aagttctgtt
    33361 tgaaagaacc atataataga agaaacatct acttttttcg cgactttttc gtctactaac
    33421 cgtttcctta ccaattcctg taatttttga tggatactct ctgtagttgg catctctaat
    33481 ggcagtaatt gtaacaaagc atgcgtagca gttccaacag cagctgctga cacttgccga
    33541 tctttttgca aaaattttgg ttctgctagt tgttcttgcg tataacgaaa ttgacgggat
    33601 gctgctttgt tctgactgct ttccagagtc aaacgtgatt cttgtgtatc atctggatct
    33661 tcgaataatc gtttgatttc agatacagat tgataacttg tggtttgtga agaagcttga
    33721 taaggatatt catatgccag acgtttttgt aacgaatctg ctaataaagt ttcatcttct
    33781 ttcatctgct gatctaagtt aaccagttct ttttcagcaa gcaactgtct ttgttcaatg
    33841 atcgattgct gattcatcca tgaaatagaa aactgtgcat ttgaatgttg aagaagagaa
    33901 gtcgaaattt cttcctctaa gtatttctgc atttcaggat gacggatcaa tccgtaacca
    33961 atccaattca tcaagctgct tctgcccttc aaacgtagcg caggatcaaa aactaactcc
    34021 tcatgatcag ctgcttcaga ccacgtttgg atcatttgct ctttattttt ataggaaccg
    34081 acaatgaaaa gcttttgttc tgcccgagtc aatcctacat acaatttacg catttcttcc
    34141 gacaacaatt tgttttgctt tgccaatttg atggcttgaa acggtaacgt atcatataac
    34201 actcgtgttt caggatccat atagcgaatt cctgctccaa gtttttcttc aaaagcatac
    34261 cgattgcgca agtcttgtaa gttgaactcc tttgtcatat ctaacaaaaa tacaactggg
    34321 aattccaagc ctttacttgc atggatcgtc ataacgcgaa cagcattatc ttctattgaa
    34381 atgactggtt ctgctaagtc tttatctttt tcttgcattt tttcaatgaa acgcacgaac
    34441 tggtataatc ctctgaaaga actttgctcg taagctttgg cacgatcaac caatgcataa
    34501 agattggctt gtctctgtgc ccctgctggc agaccgacca catactctag atatcccgtc
    34561 tcataataga tatcccataa caagtcagtg atcgaagaac ggcgagcaag ttctcgccaa
    34621 tgctctagtt gcttgccaaa atgttccagc ttagctgcta attcatcttc gtttgatgct
    34681 tgataagcaa gcacagcatc atagtaagta tgtgcacggt tagctaatcg aatgctggct
    34741 aattctggtt caatcagacc cacgatcggt gagcgcaata cagccgcaag cggaatatct
    34801 tgatagggat tatcgattaa ttgtagcagc gagatcatcg tgcgaatttc tgtcgcttga
    34861 aaatagtttt gagcatcatt catctctaat ggaatatcca atgttttgaa aatctctaaa
    34921 atcgttaagt tgttcttctt tgtaggtgtc aagagaacaa tgtctttgta ctctatcgga
    34981 cgactttttt ttgatttttt atcataaatc ataaaggagg aatcaattaa ttgacgaatt
    35041 tttagtcctg tcataaaaag ttcgccttct gttttgtctt ccagtatatc atccgtcgga
    35101 atctcaatct ctgattcttc ctgttctttt tcatagatca tgatttccgg ctcaaactgt
    35161 tcattctctg gaaagtctga aaatccttgg atcagtttgg ctgcttcgtc ataattgatt
    35221 tgacccactg ctggatccat tagttgttca aaaataagat tcgtaaaaga aaggacttct
    35281 tttctagagc ggaagttctc agccaaaacg attcgacgtc cgccttcttt ctttgagaaa
    35341 ttctcgtatt tcccgataaa taaactagga tctgctaaac ggaaagaata gatggattgt
    35401 ttgacatccc caaccatgaa catatttcct tttgtatcat cgggttctct tagccagtat
    35461 aaaatggctt cttgtaattg gttcacgtct tgatattcat ctaccattac ttctttgaat
    35521 ttttttcgat aatgttttga agcttcactt ggcagccata catctttcgt tttttctgtg
    35581 agaatctgca acgctaaatg ttccagatca ttgaaatcca gcacaccttt ttcccgttta
    35641 cgcatactga aaccgtccat gaagctttgc gtgacttttg tcatttcttc gactaacggt
    35701 agtgctttgt ccgttaattc ttccatttgg cttggggaaa caggaaaata acttttactt
    35761 atctgctgaa tcagtttttt tgctttatcc ctcatgccct tgacttcatt ggaaatttct
    35821 ttcaattctg ctttccgact gctcttaaaa gttgaaaaag ttagttgttc caaaccagca
    35881 taagcttctt ctaaccgatc ttgcgagaac gcttcataga tattcttgat ctgctgttgt
    35941 tctccagcta cttgctcatg cattttttct aatccttcac cttgtgctaa ctgagtcatc
    36001 tgttcatata actgtacaca ttggtatata tctgccaaaa ctaaaggacg gatttgtttt
    36061 tgatataatc gagatttcgc tagcccctca ggcaaacgat aattatcgct taactgttct
    36121 agccattttt gggggtcagg gttggcacgg gcaaactcat aaagagaaaa caccagattc
    36181 gtcaagccgt catctgaacg atcattagaa aaattcattg ttaattggaa aaatcgttca
    36241 tcattttctg cataaagtgc ttctctcagc tcgtcccaca catcctcctt catcaagatc
    36301 gtttctgttt catctgttaa catgcgaaag actggatcaa tatcaattaa gtaataataa
    36361 cgtcgaataa ctgtcaggca aaaagcatgt aaggttgaga tattcgctgt gggcaataaa
    36421 actaactgct tagtaaaatg ctgtctacgt acagggtcac tttcgctatt gacggattct
    36481 tgtaatgcct cttgaattct ttctttcatt tctcttgcgg cagcttcagt aaatgtcaca
    36541 atcaataatt catcgatatc aaaacccatt tttagttttt caatcactct tcgaacaagc
    36601 actgtagttt tacctgatcc ggcagacgca gagactaata gattatctcc ttgatcaaaa
    36661 atcgcttgcc actgatcatc tgtgaatcgt tcattttgcg gttttaaagg aatttgattc
    36721 actcttcttc actccttttc aatattctac gcagtgcttc ttccttatct attttctcca
    36781 gacggtggta attattttct ttcagcatca catcaaacgt acagatgctt ctgaatggac
    36841 aaaattcgca ggcaatccgc tgtttatctt tataagctgg atttagtttg atttctccgg
    36901 aagtaatcgc atctccagct aaccgcatat tttcccgatt atgcgccatg aatagttgca
    36961 gttcttcttc cgtgaaaaat ttgtctttac tgaaactacc tttttggtat tcatctttcg
    37021 catttttttt cactggatag atcagtgatt gttcttttgc ttccagtgaa tgatctagta
    37081 cttctaaaag agcgggatca tcgacaaaaa cgccatcata actaaatttt ttcaatgtat
    37141 tcttctctac atcatctgtc tccgtcaata caggattatg aacatgtaaa taatatgatc
    37201 ctgctggttt aacagccgcc tttccagtca aacgtaccgc atccatcaat gctacgtcca
    37261 gatacgtcaa taattgcata gccatgccat aataagcttc tgtgacatcg aatgaacgtc
    37321 cgctagattt gtaatcaacg acgcttagcc aagtatcttc ttgttcagaa gctacatcga
    37381 ttcgatcgat tttccctcga acatggagtt ttccaccatt actcaacggt aattccagac
    37441 ctgtgatacc ttttgctcca gcaatctgac caaatagaat ctctgtctga agaggatgca
    37501 tgcctgtatt tttgctctgt ttttgcaaag cccatgtcac tttttgaatc gtctgtccta
    37561 actggtagcg gatatagttc attcttgcag aactatccaa tatctcaaac cgaagttctc
    37621 cgaatacttc ctgcagcact ttttcagtaa agtctctacg ctgcgcatcg gacatattca
    37681 ctaaggataa ttggtttgaa aacagtagct tgaagaaacg atccaatgat tcatgataaa
    37741 aatcaccagt tgctgctgga gttagaccat aaacagttcg ttctttcaat ttcaaaccaa
    37801 attgcatgaa gtatttgtat tcacaattat aaaaattctc catacgtgaa attgaagtat
    37861 aaatctcttt tccataaagc tcttccgcca ttttttctgg catcgaaaca ggaacattta
    37921 aatgttcctg actttcaaaa atctgtaaag caaaatttcg ccatgacgaa ttcagtacta
    37981 attctttgag cttttgccag tgctttggta caggtttttt ttcatctaaa gctaatcgat
    38041 aaatcctatt gactgtattg attccgcttc tgtaagtccc tacataacaa ttagggtcgc
    38101 tttcgatcgt caaatgctct tttctctcga cgggaacaga taaatattct gtgattctac
    38161 gcaaataagg agacatcttc agcgaaccat ctgtgtcata gctttgtgca taactaagat
    38221 ataatcgatc tgttccggaa agaaaaacaa gataggcttg gaaaggctca aaagagatac
    38281 tttcctttga tgggtcgaat aaaaactgtc catctggcaa ggcctgattt aatacttctc
    38341 gttcttcact ggacaacaat ccttttgtct cttttcggtc tggaaacact tgatcattca
    38401 accctaatgc aaaagtgacg gcagcttgat ttggtcgaac taattccaaa cgattgattc
    38461 gcacttggtc gattgcggta gggattttac cataacttag attttctaga ccacttgtaa
    38521 tgatttcttg gaacagtgac cagtcaaaag ccgattcacc ataaattact acatattcat
    38581 ccaacagatc aatcagcgct ccccatgtct gctcatggtt tcttgccgct tctaagtttc
    38641 ctctgtctac ttcctgatta cgccaaaaca ataattgttg ctgtacgcca ctttggatca
    38701 aaaattgata aaaaacattt gcggcctctt gtcctgtttt gcttttcttt atttttttca
    38761 aaaatactgg tacagctttc tgaaataatc gtctaatcgt atttgactgt tcttccaaat
    38821 actgtacgtc ttcaatctgt tctgcttcaa aatcatacgc cacaaactgc cagtcttttt
    38881 cacgagtcca ataagttcct tgataattgt aagcaagtgc tacattttca gtgatgtcca
    38941 gttttttcct gaattcatct cgctcttgtt tccattcatc aagttcggtt tctgcttccg
    39001 tcgacagaaa taattcagtt ttgaaaaaac gcataatatc acttagccga taagaatagc
    39061 ggtcaagagc gaacagactg ttgatccatt cgatcagcgg atgattttcc atcatttgtt
    39121 cttcatcgat ataaaaagga attgccattt cttgaaagat cggccgaagg atatttccat
    39181 ataaagacat attttttgtc agcacttgga tatcacgata acggtagttt tcttcactga
    39241 ctagtcgtct gatttcaaca gctaattgtc ggacttcttc agttggattt tcagcttccc
    39301 acaaatggag atgctcttgt ccccctattt tgtgtactgc cgctttcttt tggctagatg
    39361 tctcttccca cattgtttgc agcagttgaa gctctgtcgg acgagtctgc tctggtgcaa
    39421 atcggtccac taatataggg actttccgtt ctcttgcact ttgaaaaaga cggaaataaa
    39481 gctttccagt ctcatgaaag agcgtaagta cttctggaag atccgctgta taaggacgat
    39541 ccagcaataa atcgacaacc aattgcccct tttccatcat tgcctgcagt aattgatact
    39601 cttgaccatt gattcgagaa aaaccactga caataaattt gacgttgttg aaatcttgtg
    39661 tctgcatata atttgctagt atagatagtg catcttcatt tgttagtgca cgttgagtca
    39721 attcgctgtc ataagctgaa aaaatcagct tcaagtcttt cattttaagt tgctggtctt
    39781 ctgcattagg tgaatcacca aataaaagca tcaggtcttc tggttgaata tttcctgtac
    39841 gcaattcact gtagagttct tgtaattgac gaataaaccc tcttttattg atttctccgc
    39901 gaaagattgt taattcttcc tcattttttt ctaaaatctg tcgcaagatc attgcagatc
    39961 ctgattctga taattcattt cctgtaagaa gagttgtctg ttgcagcaaa taccaagcca
    40021 gacgataaaa actaaatact tgaacgtttg ttgtgctgaa agtttttttt ccgcttcttc
    40081 ttcgcatctc cgctaaaatt tcttgttcct gttcgaattt gctgtagttg ggaacaagga
    40141 aaaatacttg gttacttgca tcctggtcga gccaagcgga tgcttcgtcg atcaagactt
    40201 gacggtgatc ttttttcccg tttccaagaa taaattgtaa agacatgctt ttcctccttc
    40261 aacacatgat acggtgctcc tttattatat caaaaaatac tgaacatttg ttctatattc
    40321 ttcaaattat atccttttaa ggttctgata tttctacttt tttaagtata cgc
//
LOCUS       DARPZJ010000022        35719 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.023, whole genome shotgun sequence.
ACCESSION   DARPZJ010000022 DARPZJ010000000
VERSION     DARPZJ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.023"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..705)
                     /locus_tag="SLE23_001385"
     CDS             complement(<1..705)
                     /locus_tag="SLE23_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEI8468299.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
     gene            1393..1551
                     /locus_tag="SLE23_001386"
     CDS             1393..1551
                     /locus_tag="SLE23_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468300.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1623..2849
                     /locus_tag="SLE23_001387"
     CDS             1623..2849
                     /locus_tag="SLE23_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8468301.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="SLE23_001388"
     CDS             complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="SLE23_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEI8468302.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="SLE23_001389"
     CDS             complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="SLE23_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEI8468303.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4308..4775)
                     /locus_tag="SLE23_001390"
     CDS             complement(4308..4775)
                     /locus_tag="SLE23_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEI8468304.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4895..6433)
                     /locus_tag="SLE23_001391"
     CDS             complement(4895..6433)
                     /locus_tag="SLE23_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HEI8468305.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6513..7199
                     /locus_tag="SLE23_001392"
     CDS             6513..7199
                     /locus_tag="SLE23_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEI8468306.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="SLE23_001393"
     CDS             complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="SLE23_001393"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8468307.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="SLE23_001394"
     CDS             complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="SLE23_001394"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEI8468308.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8685..9815)
                     /locus_tag="SLE23_001395"
     CDS             complement(8685..9815)
                     /locus_tag="SLE23_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEI8468309.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9815..11998)
                     /locus_tag="SLE23_001396"
     CDS             complement(9815..11998)
                     /locus_tag="SLE23_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEI8468310.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11995..13020)
                     /locus_tag="SLE23_001397"
     CDS             complement(11995..13020)
                     /locus_tag="SLE23_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8468311.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13065..13892)
                     /locus_tag="SLE23_001398"
     CDS             complement(13065..13892)
                     /locus_tag="SLE23_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEI8468312.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13889..14956)
                     /locus_tag="SLE23_001399"
     CDS             complement(13889..14956)
                     /locus_tag="SLE23_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HEI8468313.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14982..15818)
                     /locus_tag="SLE23_001400"
     CDS             complement(14982..15818)
                     /locus_tag="SLE23_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8468314.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15815..16684)
                     /locus_tag="SLE23_001401"
     CDS             complement(15815..16684)
                     /locus_tag="SLE23_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8468315.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16754..18037)
                     /locus_tag="SLE23_001402"
     CDS             complement(16754..18037)
                     /locus_tag="SLE23_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEI8468316.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18051..19736)
                     /locus_tag="SLE23_001403"
     CDS             complement(18051..19736)
                     /locus_tag="SLE23_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HEI8468317.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20011..21036
                     /locus_tag="SLE23_001404"
     CDS             20011..21036
                     /locus_tag="SLE23_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8468318.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="SLE23_001405"
     CDS             complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="SLE23_001405"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEI8468319.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="SLE23_001406"
     CDS             complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="SLE23_001406"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEI8468320.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29708..30676
                     /locus_tag="SLE23_001407"
     CDS             29708..30676
                     /locus_tag="SLE23_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8468321.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30694..31599
                     /locus_tag="SLE23_001408"
     CDS             30694..31599
                     /locus_tag="SLE23_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468322.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31596..32402
                     /locus_tag="SLE23_001409"
     CDS             31596..32402
                     /locus_tag="SLE23_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8468323.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32538..33527
                     /locus_tag="SLE23_001410"
     CDS             32538..33527
                     /locus_tag="SLE23_001410"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HEI8468324.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33844..34368)
                     /locus_tag="SLE23_001411"
     CDS             complement(33844..34368)
                     /locus_tag="SLE23_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HEI8468325.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34655..>35719
                     /gene="scm"
                     /locus_tag="SLE23_001412"
     CDS             34655..>35719
                     /gene="scm"
                     /locus_tag="SLE23_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEI8468326.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        10272 a         7539 c         6612 g        11296 t
ORIGIN      
        1 aataaatata gtatctccat aggctttttt taaattctct tcattaaata cagattctac
       61 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
      121 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa
      181 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
      241 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
      301 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
      361 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
      421 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
      481 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
      541 tccctgatga gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt
      601 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
      661 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
      721 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
      781 ttttataatt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
      841 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
      901 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttaaagtgga tagcgggttg
      961 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     1021 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     1081 tgtttatcgt tattaatagt gaataggaaa aaacctattt ttgatcattg acaattaaat
     1141 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     1201 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     1261 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     1321 atgtgcttac ccaaagcaat tcaaaaattc taatcttttt taggagatga ttttataaaa
     1381 ttgagagtct acttgaataa aaaacaaacc tgtgagtttc taggaattga taataatact
     1441 ttagataagt ggattcgtat atataatttt ccagtaatca gaattgacgg tatagttcgc
     1501 tttgacatag aggatatcaa agattttatg aatacattta aaacaatttg aaaatttctt
     1561 ctcgccgcat atactaagaa tagcgaaata tactgcctta ctttttaagg gagtgaggaa
     1621 ttttgcctac aaaactttca aatgggaaat ataaaactaa tctgaggtat ccaaaaaaat
     1681 tcagagaaat cactggaatt acatcagaaa agtatcaaaa agtatttcca actaggcaat
     1741 tggctattaa agccgaaaat gcaatgaaaa ggaaaattga aacagtttta agagaggaga
     1801 atgcaaattc actagaatta aaaggaaaaa taaaatttaa ggaattctat gaatcaaaat
     1861 ggcttcctag atatgaacta ggtcagacta ctagatcaaa aagagctcca agttacgtaa
     1921 caattagtaa tactaaagat atattccgat tgcacatcct tccaatgttt ggtgagtatg
     1981 caatgaacta tctaaattca aatactgaga taatatcaga tgaattaaca aaaaaatcga
     2041 aagaatacgc aaatataaaa attatcaaag gatatgtccg ttctatgttt gatattgcag
     2101 aaatactaaa ttatattgaa tttaaccgaa ctaccaaaat tattcaatgt atcactgcac
     2161 ctaaaaaaat tgctttagaa gaaagaagga tacgggaagg taatcaagca ttatcgtcag
     2221 aagagcttat tgcttggata gaagcagtaa acactgactt gaataatcac ttgcttactc
     2281 ttcatgacta tactcttttc atgcttaccc tatatcttgg tgatagaaaa agtgagacgt
     2341 atgctttgca atggaaatat atcgactttg agaaacaaac ggttcgcctt aaacatgctt
     2401 tggataaata tcaaaaaaag aaatttacaa aaggtcgaaa ggataccgta attcaagtac
     2461 ccgaaattgt aatggcatta ctaagcaaat ggaaatcagt gcaagctgag caattgttga
     2521 gattaaaaat taatcaaaca ccagatcagt atctctttac ctatactaaa ccatccggag
     2581 aagtaaattg ccctgttcac gctgattacc taaactatcg aatcaattca attaaaagac
     2641 gacatcctga attggctcat ttatctccac ataagcttcg tcatacctat gcaactatag
     2701 ctagacaagg cggagcaaat atgaatcaaa tatctagtgc tttaacacac tcagatattt
     2761 ctacaacgag aatatacgta aatacaccag atgtagtaga taaaactgtt tttgaagcct
     2821 ttcagagagg attgaataaa tgtgattagt atgtgttctt aaatgtgttc ttaaacaaga
     2881 aaaagacact tttcaaacaa ttgaaaagtg ccttgaaaca ttgatatata aataatatta
     2941 acgtttagag aattgagatg ctttacgagc ctttttgaga cctggttttt tacgttcgac
     3001 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
     3061 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
     3121 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
     3181 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
     3241 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
     3301 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
     3361 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
     3421 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
     3481 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
     3541 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
     3601 cactttgtct gcattgatga cgatgacgaa atcaccagta tccaaatgag gtgtgaaagt
     3661 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
     3721 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
     3781 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
     3841 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
     3901 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
     3961 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
     4021 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
     4081 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
     4141 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
     4201 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
     4261 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
     4321 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
     4381 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
     4441 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
     4501 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
     4561 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
     4621 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
     4681 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
     4741 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
     4801 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
     4861 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
     4921 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
     4981 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
     5041 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
     5101 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
     5161 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
     5221 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
     5281 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
     5341 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
     5401 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
     5461 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
     5521 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
     5581 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
     5641 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
     5701 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
     5761 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
     5821 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
     5881 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
     5941 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
     6001 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
     6061 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
     6121 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
     6181 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
     6241 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
     6301 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
     6361 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
     6421 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
     6481 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
     6541 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
     6601 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
     6661 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
     6721 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
     6781 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
     6841 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
     6901 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
     6961 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
     7021 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
     7081 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
     7141 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
     7201 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
     7261 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
     7321 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
     7381 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
     7441 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
     7501 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
     7561 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
     7621 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
     7681 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
     7741 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
     7801 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
     7861 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
     7921 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
     7981 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
     8041 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
     8101 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
     8161 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
     8221 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
     8281 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
     8341 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
     8401 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
     8461 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
     8521 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
     8581 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
     8641 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
     8701 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
     8761 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
     8821 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
     8881 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
     8941 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
     9001 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
     9061 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
     9121 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
     9181 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
     9241 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
     9301 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
     9361 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
     9421 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
     9481 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
     9541 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
     9601 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
     9661 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
     9721 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
     9781 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
     9841 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
     9901 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
     9961 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    10021 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    10081 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    10141 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    10201 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    10261 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    10321 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    10381 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    10441 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    10501 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    10561 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    10621 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    10681 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    10741 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    10801 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    10861 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    10921 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    10981 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    11041 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    11101 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    11161 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    11221 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    11281 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    11341 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    11401 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    11461 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    11521 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    11581 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    11641 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    11701 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    11761 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    11821 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    11881 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    11941 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    12001 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    12061 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    12121 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    12181 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    12241 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    12301 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    12361 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    12421 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    12481 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    12541 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    12601 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    12661 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    12721 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    12781 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    12841 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    12901 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    12961 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    13021 ttatttctct ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    13081 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    13141 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    13201 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    13261 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    13321 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    13381 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    13441 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    13501 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    13561 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    13621 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    13681 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    13741 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    13801 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    13861 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    13921 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    13981 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    14041 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    14101 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    14161 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    14221 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    14281 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    14341 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    14401 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    14461 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    14521 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    14581 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    14641 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    14701 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    14761 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    14821 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    14881 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    14941 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    15001 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    15061 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    15121 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    15181 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    15241 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    15301 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    15361 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    15421 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    15481 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    15541 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    15601 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    15661 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    15721 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    15781 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    15841 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    15901 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    15961 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    16021 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    16081 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    16141 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    16201 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    16261 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    16321 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    16381 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    16441 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    16501 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    16561 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    16621 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    16681 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    16741 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    16801 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    16861 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    16921 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    16981 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    17041 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    17101 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    17161 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    17221 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    17281 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    17341 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    17401 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    17461 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    17521 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    17581 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    17641 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    17701 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    17761 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    17821 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    17881 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    17941 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    18001 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    18061 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    18121 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    18181 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    18241 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    18301 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    18361 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    18421 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    18481 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    18541 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    18601 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    18661 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    18721 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    18781 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    18841 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    18901 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    18961 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    19021 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    19081 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    19141 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    19201 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    19261 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    19321 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    19381 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    19441 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    19501 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    19561 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    19621 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    19681 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    19741 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    19801 tgtcaatagc atttttttaa ataattttga tatacacaaa aatacaaata agaaagctta
    19861 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    19921 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    19981 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    20041 aaagctaatg tctcaaaatc aactgtctcc agagtattaa ataaccagcc aaatatctct
    20101 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    20161 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    20221 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    20281 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    20341 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    20401 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    20461 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    20521 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    20581 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    20641 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    20701 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    20761 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    20821 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    20881 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    20941 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    21001 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    21061 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    21121 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    21181 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    21241 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    21301 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    21361 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    21421 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    21481 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    21541 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    21601 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    21661 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    21721 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    21781 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    21841 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    21901 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    21961 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    22021 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    22081 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    22141 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    22201 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    22261 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    22321 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    22381 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    22441 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    22501 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    22561 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    22621 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    22681 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    22741 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    22801 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    22861 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    22921 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    22981 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    23041 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    23101 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    23161 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    23221 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    23281 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    23341 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt tgaatcgttt
    23401 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    23461 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    23521 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    23581 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    23641 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    23701 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    23761 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    23821 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    23881 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    23941 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    24001 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    24061 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    24121 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    24181 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    24241 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    24301 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    24361 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    24421 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    24481 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    24541 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    24601 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    24661 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    24721 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    24781 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    24841 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    24901 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    24961 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    25021 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    25081 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    25141 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    25201 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    25261 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    25321 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    25381 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    25441 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    25501 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    25561 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    25621 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    25681 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    25741 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    25801 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    25861 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    25921 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    25981 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    26041 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    26101 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    26161 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    26221 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    26281 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    26341 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    26401 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    26461 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    26521 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    26581 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    26641 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    26701 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    26761 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    26821 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    26881 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac cgtcatgttt
    26941 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    27001 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    27061 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    27121 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    27181 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    27241 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    27301 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    27361 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    27421 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    27481 acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca attcgccaag
    27541 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    27601 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    27661 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    27721 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    27781 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    27841 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    27901 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    27961 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    28021 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    28081 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    28141 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    28201 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    28261 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    28321 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    28381 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    28441 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    28501 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    28561 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    28621 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    28681 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    28741 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    28801 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    28861 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    28921 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    28981 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    29041 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    29101 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    29161 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    29221 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    29281 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    29341 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    29401 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    29461 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    29521 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    29581 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    29641 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    29701 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    29761 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    29821 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    29881 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    29941 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    30001 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    30061 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    30121 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    30181 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    30241 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    30301 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    30361 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    30421 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    30481 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    30541 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    30601 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    30661 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    30721 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    30781 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    30841 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    30901 gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    30961 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    31021 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    31081 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    31141 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    31201 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    31261 atttctaatg gatgcattgc tctttctggc tccttacttg cgcaaaacaa cggctttgct
    31321 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    31381 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    31441 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    31501 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    31561 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    31621 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    31681 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    31741 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    31801 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    31861 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    31921 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    31981 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    32041 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    32101 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    32161 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    32221 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    32281 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    32341 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    32401 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    32461 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    32521 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    32581 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    32641 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    32701 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    32761 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    32821 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    32881 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    32941 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    33001 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    33061 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    33121 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    33181 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    33241 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    33301 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    33361 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    33421 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    33481 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    33541 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    33601 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    33661 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    33721 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    33781 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    33841 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    33901 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    33961 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    34021 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    34081 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    34141 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    34201 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    34261 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    34321 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    34381 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    34441 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    34501 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    34561 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    34621 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    34681 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    34741 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    34801 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    34861 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    34921 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    34981 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    35041 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    35101 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    35161 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    35221 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    35281 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    35341 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    35401 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    35461 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    35521 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    35581 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    35641 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    35701 tgatagctca gattcatca
//
LOCUS       DARPZJ010000023        35213 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.024, whole genome shotgun sequence.
ACCESSION   DARPZJ010000023 DARPZJ010000000
VERSION     DARPZJ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.024"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(66..686)
                     /locus_tag="SLE23_001413"
     CDS             complement(66..686)
                     /locus_tag="SLE23_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HEI8468327.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(878..1174)
                     /locus_tag="SLE23_001414"
     CDS             complement(878..1174)
                     /locus_tag="SLE23_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEI8468328.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            1378..2028
                     /locus_tag="SLE23_001415"
     CDS             1378..2028
                     /locus_tag="SLE23_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEI8468329.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            2044..3771
                     /locus_tag="SLE23_001416"
     CDS             2044..3771
                     /locus_tag="SLE23_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468330.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            3768..5660
                     /locus_tag="SLE23_001417"
     CDS             3768..5660
                     /locus_tag="SLE23_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468331.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            6364..7233
                     /locus_tag="SLE23_001418"
     CDS             6364..7233
                     /locus_tag="SLE23_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HEI8468332.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            7442..8467
                     /locus_tag="SLE23_001419"
     CDS             7442..8467
                     /locus_tag="SLE23_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEI8468333.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            8506..9456
                     /gene="manA"
                     /locus_tag="SLE23_001420"
     CDS             8506..9456
                     /gene="manA"
                     /locus_tag="SLE23_001420"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEI8468334.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            9550..11253
                     /locus_tag="SLE23_001421"
     CDS             9550..11253
                     /locus_tag="SLE23_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8468335.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            11255..13288
                     /locus_tag="SLE23_001422"
     CDS             11255..13288
                     /locus_tag="SLE23_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEI8468336.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            13299..13739
                     /locus_tag="SLE23_001423"
     CDS             13299..13739
                     /locus_tag="SLE23_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8468337.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(13939..15066)
                     /locus_tag="SLE23_001424"
     CDS             complement(13939..15066)
                     /locus_tag="SLE23_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468338.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(15069..15746)
                     /locus_tag="SLE23_001425"
     CDS             complement(15069..15746)
                     /locus_tag="SLE23_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468339.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            16010..17776
                     /locus_tag="SLE23_001426"
     CDS             16010..17776
                     /locus_tag="SLE23_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEI8468340.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            17791..18228
                     /locus_tag="SLE23_001427"
     CDS             17791..18228
                     /locus_tag="SLE23_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8468341.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            18241..19392
                     /locus_tag="SLE23_001428"
     CDS             18241..19392
                     /locus_tag="SLE23_001428"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEI8468342.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19454..20152)
                     /locus_tag="SLE23_001429"
     CDS             complement(19454..20152)
                     /locus_tag="SLE23_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEI8468343.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20145..21497)
                     /locus_tag="SLE23_001430"
     CDS             complement(20145..21497)
                     /locus_tag="SLE23_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEI8468344.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(21720..23120)
                     /locus_tag="SLE23_001431"
     CDS             complement(21720..23120)
                     /locus_tag="SLE23_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEI8468345.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            23281..24018
                     /locus_tag="SLE23_001432"
     CDS             23281..24018
                     /locus_tag="SLE23_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEI8468346.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            24143..24622
                     /locus_tag="SLE23_001433"
     CDS             24143..24622
                     /locus_tag="SLE23_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HEI8468347.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            24619..25386
                     /locus_tag="SLE23_001434"
     CDS             24619..25386
                     /locus_tag="SLE23_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468348.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            25616..26185
                     /gene="lepB"
                     /locus_tag="SLE23_001435"
     CDS             25616..26185
                     /gene="lepB"
                     /locus_tag="SLE23_001435"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEI8468349.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(26289..26891)
                     /locus_tag="SLE23_001436"
     CDS             complement(26289..26891)
                     /locus_tag="SLE23_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8468350.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26997..27466
                     /locus_tag="SLE23_001437"
                     /pseudo
     CDS             26997..27466
                     /locus_tag="SLE23_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            27572..28156
                     /locus_tag="SLE23_001438"
     CDS             27572..28156
                     /locus_tag="SLE23_001438"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEI8468351.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            28159..29232
                     /gene="prfA"
                     /locus_tag="SLE23_001439"
     CDS             28159..29232
                     /gene="prfA"
                     /locus_tag="SLE23_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEI8468352.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            29225..30064
                     /gene="prmC"
                     /locus_tag="SLE23_001440"
     CDS             29225..30064
                     /gene="prmC"
                     /locus_tag="SLE23_001440"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEI8468353.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            30057..30236
                     /locus_tag="SLE23_001441"
     CDS             30057..30236
                     /locus_tag="SLE23_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468354.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            30258..31283
                     /locus_tag="SLE23_001442"
     CDS             30258..31283
                     /locus_tag="SLE23_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEI8468355.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            31458..32702
                     /locus_tag="SLE23_001443"
     CDS             31458..32702
                     /locus_tag="SLE23_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEI8468356.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            32855..33802
                     /locus_tag="SLE23_001444"
     CDS             32855..33802
                     /locus_tag="SLE23_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8468357.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            33936..34565
                     /gene="upp"
                     /locus_tag="SLE23_001445"
     CDS             33936..34565
                     /gene="upp"
                     /locus_tag="SLE23_001445"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEI8468358.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(34704..34946)
                     /locus_tag="SLE23_001446"
     CDS             complement(34704..34946)
                     /locus_tag="SLE23_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468359.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            35067..35139
                     /locus_tag="SLE23_001447"
     tRNA            35067..35139
                     /locus_tag="SLE23_001447"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35100..35102,aa:Thr,seq:cgt)
BASE COUNT        11827 a         6271 c         7196 g         9919 t
ORIGIN      
        1 caaggcacaa atgctgcttt gaagattttt tcctctgtct cttttgtatg catttatctc
       61 aatttttaaa atgatttacc taaagcagca gctttatcta atgcattttg catcaactca
      121 tctgcacggt cagggtcata atcgattcct tcgatgaata gctgatctac ttgatcgatg
      181 cctacaaagt ttaaaatacc ttttacatat tgagaggcaa agtcttgtcc gttgtataca
      241 ccgccattag attggatgtg cagtgctttt ttacctgtca ctaatccttc tggcccgttt
      301 tctgtatagc ggaacgtttt tccagctaca ttgacggtat cgaaccaagc ttttaatttt
      361 gttgggatat ttagattcca taaggcgttt gcgataacga ttttatcagc agcaaggaac
      421 tgatcagtca attcattgaa acgagcaatt ttttgttgtt gactttctga taaggaagtg
      481 aattctgcac cagcacgtaa tgcttcccaa cctgataata attcttcatc gatttccgga
      541 atatcatcgc gataaagttc caaaacagtc acttcatcat ctggatgatt ttctttataa
      601 cttgttaaaa aagacgtcaa tgccttaact gtgcgcgatt cttctgcagt taggggatga
      661 cctttgacta ctaaaacaga tgccatatgc ttaccttctc cttttattgc tatgattgtt
      721 ataactatga ctaacaaaat cagtttactc gaaaaagaaa aggctatcaa gtcatattga
      781 taaggttgaa gaataaataa ctaaaaaaag acagggtata aaagaggctg tgacacgatt
      841 ttttgtcaca gcctcttttg aatctaacaa gcaatattca agcaacactc gactgaagag
      901 cttccatccc accaatgata taaacagcac gaaaaccatt agcagtaagt tgatcggcta
      961 atgcttctga tcgcctgcct gtatagctta gaatataata aagtttcttt ggatctagat
     1021 tttttaattg tcttggcaag atagcagcgg ggatagaaag cgagtggctt aagtggtttt
     1081 ttgtgtaatc taaggtattt cttgtatcta aaacgatgct gtcagcatcg agaggcaatt
     1141 tattgaagtc ttggacacta attgattggg ccatttatct catcctttgt ttagtatgtg
     1201 gctattttaa tgggcaactc tcattaattc aaatggaagg attcctctta tcactttttt
     1261 aatgtatcgg atgataatga aaaaaactat gcaaatgtct tgcaaaacag gtaggaggtg
     1321 ttataatgac atagcgtcat atgacaatgt gtcatcttga aagaaaggag aatccatatg
     1381 ccgacacaga catttttcca tttgcctaaa gaaaaacaaa aaagactaat cgaggctgcg
     1441 agaatcgagt tttctagagt acccttaaaa gaagcttcga ttgctaatat cgtcaaatta
     1501 gcggatatcc ctagaggcag tttctatcag tattttgaag ataaagagga tctttatttt
     1561 tattactttg agacaatgag acgtgacagc tctaaagata tgttacaact aatgaaagaa
     1621 tccgatggtg atctattcaa aggattcgaa tcctattttt ctaaaatgat ttatgagatt
     1681 ttggaaggcg agaatgcttc tttttatcgt aacttgttta tgaacatgga ttaccgtgcc
     1741 tcaagaaaag tcgctcctca tacgagtcgc caaaaaacgc ctcacgatcc acataaagaa
     1801 cacaaacaag atgcaaaaga gttgcttgaa ttgatcgatc ggacgaagct gaaagtaaaa
     1861 aatgatcatg aattggaatt actgatccaa ttagtgatga atactgtatt tacaacaatt
     1921 gcgcattcgt atcgcttatt ttcaacatct gaagattact cagtagagca agcaatcagt
     1981 gaattcaatt tgaaactttc ttggctgaaa aacggagtat ataaatagaa agaagggaac
     2041 tagatgctaa aaatcgtaaa acggatctcc ttgacttcag caattgcagc tgcagttttc
     2101 atggtgatcc aagtactggc agatttatat ttgccgacac ttacctccaa tattattgat
     2161 aaaggggtag cgcaaggaga tgtcgattat atttggcata caggttttgt gatgatcggc
     2221 ttttctttga tcagtatctt agctgctatc gcaaatacat tttttgctac tcgtgaatca
     2281 cagaaactgg gtaagcaatt gcgtacggat gtctataaaa aatcagagag tctgacaaaa
     2341 gatgcgtttg ataaatatgg aacggcctct ttgatcacaa gaacgaccaa tgatgtgact
     2401 caaatccaaa tggttacaca aatgttttta cgtatgatga tcaatgcacc aatcacgttg
     2461 attggcgcga gcatacttgc ttatcaaaaa gatcatcagt tgacaaaaat cttcttagtt
     2521 gtcatcccag taatgattat tttgatcggc ggaatcatgt actttgctgt tccattattc
     2581 aaaagtatgc aaaagaaaac tgaccgttta aacctggtat ttcgagaagg attgacaggg
     2641 gtcagagtga ttcgagcatt cgataagaca cgctttgaag aaaatcgttt tgatttagcg
     2701 aataaagatt atacaaatac ggcaatcaaa gttaatacga tcgtcgcatt gatgatgcca
     2761 atgatgacat tgatcatgag cggtacaaac gtagcaatca cttggtttgg tggacactac
     2821 atagcagata tgactttgga agtcggtaat ctgattgcat ttatgactta tgcgatgcag
     2881 atcttgatca gctttatgat gctttccgct atttttatca tggtgcctcg tgcacaagct
     2941 tcagctgacc gtattaatga agtgttggat gaaaaaatcg gtatccatga ccctgaaaat
     3001 cctaaaacag tttcttttgc tggaaaaaac gcaacattgg ccttcaatca tgtcaattat
     3061 cgatatcatg gagcagaaaa acttgcattg gaagatattg atttccaagc caagtcgggc
     3121 gagatcgtcg caatcatagg ggggactggt tcaggtaaaa cgaccttagt caatttgatc
     3181 cctcgattat atgacatcga atctggttcg atccaaataa atggaacgga cattagtgac
     3241 atgactcaat ataatttgcg agaattaatg ggctttgttc ctcaaaaagc agttctgttc
     3301 tctggaacga tccgagacaa tatgcagtat ggtaagccgg atgcaacaga tgaaatgatt
     3361 tggaaagcat tagaaatcgc acaagctaaa gattttgttt cagagatgga agatggctta
     3421 gatagccatg tggaacaagg aggaggaaac ttctctggtg gacaaagaca gcgtctggca
     3481 attgcacggg cattagtcaa aacagcagat atctatgtgt ttgatgattc cttctcagcg
     3541 ttggatttca aaacggatgc caatcttcgc caagcattga aaacgaatat gaaagaaagt
     3601 atcaccgttt tagttgctca acgagtaagt acagtaatgg atgcagatat gatccttgtg
     3661 ctagatgaag gaaaactggt tggcaaagga acacatgaag aactattagc aacaaacgaa
     3721 acttatcaag aaatcgttca ttcacaacta agagaggagg acttagcatg agtaaaacaa
     3781 acacacgtcc ctctcatgga ccagcaggcg gtccaggaca tggtggacct ggcagaaatc
     3841 tcggtgtaaa aggtgaaaag cctaaaaatt tctggggaac ggtacgccga ttgtttggct
     3901 atatgtctaa acgtatggtt gcgatcatcg ctgtatttgt actagcaata gcagccgtga
     3961 tcttccaaat ccaaacacca aaggtcttgg ggaaagcaac cacagaaata ttcaaaggtg
     4021 taatggctgg cgctcaacag atgcaacaag gccaacaagt aacaaaattt ccgatagact
     4081 ttgataaaat cgcgcagatc attgcgacag taatcgtgat gtatttgatt tctgctgtat
     4141 tcaacttttt acagcaattt attatgacac gtgtttccca acgaacagtt tatgaattac
     4201 gtcatgattt ggaagccaaa atgaatcgtg taccgatttc ctattatgat acacatacaa
     4261 atggggatat catgtctcga gcaatcaatg atatggataa catcgcaagc acgctgcagc
     4321 aaaatttgac tcaatttgta actagtgcag tcacattgat tggggtcatc gtgatgatgc
     4381 tttcaatcag ctggcaattg acgttagtcg cgttattgat gatcccttta agcttgatca
     4441 tcgtgatgat cgtagcgccg aaatcacaag tgtttttcgc agatcagcaa aaaagtttag
     4501 gtttattgaa taaccaagta gaagaaacat atggtggtca taccattgtt aaaacattca
     4561 atcatactga aaaagaccag gaagtatttg aaaaagaaaa tcagaatctg tatgccgctg
     4621 gttggaaagc tcaatttatt tcggcaatca tcatgccgtt gatgaatttc gttaaaaatc
     4681 taggctatgt gttcgtcgct gtactaggcg gagtaaaagt tgcaaatggg aacatgacat
     4741 taggggatgt tcaagcgttc ttgcaatata caacacagtt ctctcaacca atcactcaac
     4801 ttgcaagttt gatgaacact atccaatcaa cagttgcttc agccgaacgg gtatttgaag
     4861 tgttggatga agaagagatg tccaatgaaa aatctggcct tccagaagaa aaagatacac
     4921 catacaaagt tcgttttgaa aatgttcaat tcggctacac accagataac ttgctaatga
     4981 ctgattttaa cttggatgtc aaacctggtg agatggtcgc tattgtaggt ccgactggtg
     5041 cagggaagac gacactgatc aaccttcttg aacggttcta cgatgtttct ggaggtagta
     5101 ttcgttacga tggtgtagat acccgtgatc tttcacgtga tgaattgcgc gcacagtttt
     5161 caatggtact gcaagatact tggctgttta caggaagtat ctatgacaat atcaaatatg
     5221 ggaacgacga tgcaacagac gaacaaatca ttgaggctgc taaagctgct cacgtagacg
     5281 attttgttcg taaattgcca gaaggatata acactgtatt aaacgaggat gcaagcaata
     5341 tttcgcaagg gcagcgtcag ctaatcacaa ttgcgcgggc attcttagca aatccagatg
     5401 tcctgatcct tgatgaagca acatctagtg tagatacacg aacagaaata ctgattcaaa
     5461 aagcgatgaa ccgcctattg gaaaaccgga caagtttcgt tgttgctcac cgcttgtcta
     5521 caatacgcga tgcagacaac attattgtga tgaatcatgg ttcgatcgta gaaacaggaa
     5581 accacgatac attgatggaa aaagacggat tctatgcaga tctttataac agtcagtttt
     5641 ctgaagaaga agcttcatag aatagtacaa atttattatt ttttttaggg gctgtgacaa
     5701 aagtcgtgtc acagtccctt tttccgaata aacggtgttc aatcagctgt ccttcggtat
     5761 tagctcaaaa aacggcaaaa tatgagaagc tatttttccg ttttgtatct ctaatactca
     5821 ggtcaaaccg ctgattttac aacctcttcc ttaaacggtg ttctcctgcc aactcctcgg
     5881 tcacaagtca caatagtcaa caaacctgag aagctgtttt ttgaaattgc tccttgtgac
     5941 tcggagttaa acggcaggct cacaacctct tggtaaacgg tgttcaaaag ccagtttctc
     6001 ggtattaagc caaatttatg caaaaatgta gaaagccatt ttcacaaaat ttttcttact
     6061 actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat
     6121 ctgcggtaat aagcccaacc aaacgaaaaa taggaggagc tatttttgtt tggctgttct
     6181 tattacttga tgcagaacag ctttttcaca acctcttttt ataagagttt ttactcatta
     6241 atttacaaaa aacaagcaaa atgcgaattt tctcacattt tttttaacaa aatcaaagtt
     6301 attgcttgaa agaagaagaa tccatcgtta aaataaagct tgacgtagag gggagcaaga
     6361 aatatgaaag attttcaatt gggggctgcc acctatttaa aaagtgtagc cattcgggtg
     6421 aaagaccgag ataaaatgat tgatttttac aagaacgttg ttggctttga tttgaaaaga
     6481 gaagaaaacg aattagccat tttaggaaca gaagaagctg gaagtgaaat gttgctgctg
     6541 gaagaaagtc ctagagcgaa tgatcacatg ggggtgatca aaaagctgaa ccgtttttca
     6601 ttgattatcc ctagcacaga agaaatggca gatatccttt gtcgtatccg taaaatgaat
     6661 tatccaatca aagaagcttt agaagatcat ggacgtatgg ggattttgct cgtagaccca
     6721 gaagagaatg aattggaaat ttaccatgaa gagaataaga acgaccaaag agaaattcca
     6781 gaaacaatgg atcaagaagc attattaaga aaatctgaag aaaaattcag taaactatca
     6841 acaggttctt attttgaaaa aatccattta aatgttacta acttaacaaa agaacgccaa
     6901 tttcttaatc atgtacttgg tttgaaggta cataatgaag aagagggcat ccatgtattg
     6961 aatgaaggag atttccatgt tggtttgaca gaagctagcg gaggcgcaat tgatttgcct
     7021 acagatgaag tgattggact tgattttctg aaattcatga tcgatactga aagcatggaa
     7081 ggactgattg ctcacttgca gcaactatca gttgatttct tcttagacaa aaagcacaca
     7141 gtactcacaa tctatgatgc tataggaatc gaatggtggt tcgtcagtga gccaaaagaa
     7201 aagaataaaa ctgacattcg atgcgacgct taactttttc tttcttaacg attgtcgcat
     7261 gtctcgtcat tttatgaacg gtcatactat cgcttattct agagatagaa agagaaaata
     7321 gtataccggg ggaaactgcg cggtttttcg cgcagttttt ttgtgtaaaa aaggttgatt
     7381 cctcatagat taagctttaa gcttggactg taagaatctg atagaaaagc aggagaaaaa
     7441 gatgtatcca cacacgaaac agcttatttt gaaaaagatg gaagaaggat tttatccagg
     7501 tgtagcagtc gccttcataa aagaaaatca agtagaaaca tttacagccg gctttgccca
     7561 agtcgttcct gaaaagcagc tgatgacaga agatctgttg tttgatgcag cctcactgac
     7621 gaaagtcgtt gcaaccactt cattagtttt acgtctatta gaagatggaa agatagaact
     7681 cgatcaaccg cttcataaat atcttcctga atttgaaaat cagacaatca ctttgcgtca
     7741 tttactgaca catacttctg atatcaaaac atggatacca aacagagata agctatctca
     7801 ggaagaattg atcgccgctt atttgaagct agaaccaggt gagcaactag gaaaagaagt
     7861 aaaatataca gatgccggta cgattcttct tgggttgatg ctagaggaaa tttaccaaga
     7921 aactgcagtg gaaatctttc aagaacaagt attggaacca ttaggaatga tgaacagctt
     7981 atttcttcct tttccttcca aaaaaatcgt tcccacagaa caactgcctt cgggtgaggt
     8041 tttgcgtgga caaactcatg atccgaaagc aagagttttg gctgaacatg caggtaacgc
     8101 gggtctcttt attgatttga aagacagcat tacttttgtc caaatgtatt tgaacaaggg
     8161 aaaaatccgt aatggtcgtt ttttagaaga agagacgatt gattctttac tgcaagatca
     8221 aacaccgaaa aaaaatggct atcgttcttt aggatgggac ttaaaaaagg atgtagaaga
     8281 cggtcatgcg attctttttc atactggtta tacaggtacg tttttcttga ttgatataaa
     8341 aacacaagaa gcgttgatat ttttgtcaaa tcgcgtacat cctgtcgatc atcgtgcgga
     8401 gtatctcata tgtcgagatg aaattgttga aaactttttg aaagagaaag cggtattacc
     8461 gaaataatgc tataatagct atgaaaaatg agaggagttt gaattatgca ggaacctatg
     8521 tttttaaaac cagtttttca agaaaaaatt tggggaggaa gtcgtttacg ttcagtcttt
     8581 ggttttgata tccctaacga taaaatcgga gaagattggg cgatcagtgc gcatcctcat
     8641 ggtgtcagtg tagtagaaaa tggcgaattc aaagggaaaa gattagatga actatggtca
     8701 gaacacaagg aattgtttgg ccatccttca gaaccagtgt ttccattatt gatcaagatc
     8761 ttagacgcag aagatgatct atctgtacaa gtacatccag atgatgccta tgggatgaaa
     8821 catgaaggtg aattaggaaa aactgaatgc tggtatatca tcgatgctga acctggtgca
     8881 gaaatcatct atggtcatca tgcaaagaca agagaagaac tagctgagat gatcaaagat
     8941 gggcgctggg atgacctttt gaagaaagta ccagttaaaa aaggtgattt cttttatgta
     9001 ccaagcggaa cgatccatgc tattggtaaa ggaatcatga ttttagaaac acagcaaagt
     9061 tctgacacga cttaccgcgt gtatgactac gacagaaaag atgcgcaagg acaaacaaga
     9121 gagctgcata tccaacaatc gatcgatgta acaactgtcc ctgcgaaaac accagaatta
     9181 caaatcaaag aagtccgaaa agggaattca tcgatcgtca cttatttaga aactgagttt
     9241 ttcaatgtat atgagtggga tattaaagga atcacatctt tcaaaaaaca agccccttat
     9301 acattgatga cggtaatcga aggagcagga gaccttgtcg ttgacggaaa aacatatcca
     9361 ttagaaaaag gaacaagctg tattattcca aatggcgttt ctgagtgggc ggtccaaggt
     9421 gaactagcaa tcattgcgtc tgaaccaggc aaatagttcc cagatagctg aaagcagcag
     9481 acggtttttc gtttgctgct ttttctacat aaaatccgtc catcaataaa tagaagtctg
     9541 gtgaaaaaga tggaatacaa atggaaagca aacaacagca gtcgcgtgtc tatgaaacaa
     9601 ctgagaaaag ctggacatca cctaaatgaa atgatcatgc caaatctaag tctgtttatc
     9661 gcttggggaa tcttgtcatt agcaacaaaa ggtgtgtctg gcgatttgca caccacatta
     9721 gaagaggtat gccattggat gatccagctg cttttaccca tcttgatcag ttattcaggc
     9781 gggaaatcgg tagggggaca aaaaggggca gtcgccggtg caattgcttc tttagggttg
     9841 atcgctcgtt ccaatgctcc acaaatcgta ggagcgatga ttatcgggcc gcttgccggc
     9901 atcgtatatg aacaatttgt ttctagattc catgtgaaat tcaaggctgg atatgaaatg
     9961 cttgtcagca acctactagt aggactgact ggtagcgtta tttgtataat tggaatcgtt
    10021 tttattgaac cagttttaaa tagtgttcac ttgttgctcg cctccgttgt gtcttggcta
    10081 gtcacaatga atctgttacc acttgtcagt ctgatcttag aacctctaaa agtactattt
    10141 ttcaataatg caatcaatca tggtgtattg acacctttag gaatcgaatt ctcacaaaca
    10201 gtcgggtact cttccttatt tttgatggag gcaaatcctg gacctggttt agggatctta
    10261 ctttctatcc tttgttttgc agaaaaacag gaaaaagtaa atgcgagtgg agcattgatg
    10321 atccatgcga ttggcgggat tcacgaaatc tattttccat ttgtcttgct gcgaccgtat
    10381 ctatttttag ctgtaatggc tggtggggca agcggcacgt tgatatttca atggttagat
    10441 acgggattag ctgcacctgt atcgcctggg tcactactcg tgatttttgc caatgcgcct
    10501 tatccacaac tagctggggt aagtataggg atagcaatca gtacatttgt gaccttcatt
    10561 tgtgcagcga tactattgaa attaccaaat aaagaaaaag agaacaaaac ggtcaaagaa
    10621 aggggagaaa tcttggaacc atctatcatt cattccgtca tttttgcttg cgactcaggt
    10681 atgggatcaa gtgctatggg agccgccctg ctgaaaaaga aattagcagc agaaaaaatc
    10741 gatctttctg tcggatacag ctctatctat gaattgaata accaagtaaa tcagctggtt
    10801 atcgtgcaac atgaactagc gggtcttgca agagaaaaag tacctcaaag tcaaatctat
    10861 gtactggatc actttttgga aacagatatc ttgctgtcac gaataaaaga agcgatccaa
    10921 tttccaaagc gggaagaaaa aaaagagata gcagatatca cagaacaaaa aacgtcgcct
    10981 gctaatattg tatttttgta taaaaacaac agacgcggct cacaaactat gggcatgacg
    11041 attttaagtc aattagcaaa aaaagcgaaa aaacagtttg ttatctcaaa agaatcaata
    11101 gaaaaaatca aaatccaaga agaaacgatt tatatcgcac aaagagaact agctgtaact
    11161 gaacagctag aagaaaagat ccctcggcta gttctagttg aacattgggt agctacgaat
    11221 gaatacgaaa aactcgtgaa gggagaaata taagatgtat ttatcgccca gagaaaaaca
    11281 attattagca gaatttctca gtagcccgtc acctgtatct atccaaaaaa tgatgaattt
    11341 attgaaggtc agtaaacgga ctatttaccg cgaattagat aatcttgaag tctcattgaa
    11401 atcggtaaat gcttctttga aaaaagcagc tagaggctca tttgtcattg aggcatcaga
    11461 agaagtatta gagcaattaa aagaaaatac agatgggaaa agtaatgact tatccactgc
    11521 taaacgacaa cacgcgattt tagccgagtt gttactgacg acagagccgt tgagtcttgc
    11581 tcatttcatg gaatcatatc gcatcagtaa taccactttt tatgcagata tcaaacagtt
    11641 ggaagaaagt attcgccaac tgcctttgga aatcattcgg aaccagggat acgagatcga
    11701 aggaccggaa aaataccgcc ggcttctgac agcgaatgta ttagaattag aaatcaatga
    11761 atatgaactt tttcatagta tttctttcga tgcatcactg aattattttt ttcgattcgt
    11821 tgatccgcaa catctatctc ttgcacgcaa agtaatcggg gaagaattga tccaaaaaaa
    11881 gaccaatcta agtgatagaa agcttgaaca tttggttttg atgctgacat tgacgatgga
    11941 gcgtgtgacg aaaaatcatt tactgacaaa tgagacatat aatagtctgg caaacaaaga
    12001 attactacag acagctaaac gattgttttc acggatcgct tctgagacaa aacaacttta
    12061 tccagtaaat gagatcgtct tttttgcagg attattaaat gacttcacga actcatttga
    12121 tcagaatttc tttgaagaga cgttcgatac acagcttgct tatttagtaa aacaactgat
    12181 tcaagaagta agtgaagaga cgaatgtcca tttttatgaa gatgaaactt tgtacaaaat
    12241 gctgttgact catttatctg gtgtgttttc aagagccgtt ttacaagaag agacactgac
    12301 caatccgatt ttagaaaaaa tcatggttca atacgaggaa gttgcgaatg caatccgtaa
    12361 agcagtagag cggatttttc aagaaaaaaa attatccgaa gaagagatcg cttatatggt
    12421 ccttcatttt gcgaattcat tggaacgaag tccgaaagaa agcaatatca gtattgcagg
    12481 attttcgcca agtggattag cttctactag catgttggaa ctacgattga aaaggtattt
    12541 tcccttcatc caacaaattc atttctatcg gattgctgat ttaaaaaaaa tcgatttaca
    12601 agaagaatat gatgttgtta tttctacatc tattttacca ggatacggtg gaaaatatat
    12661 tttagtctcc ccgctactgc tagaagatga agtcaagcag ctaaaagaag ctttttcgca
    12721 tattgagaag aaaaaaaggc aaaaaattac gtataacagc aataacgagt ggatgataga
    12781 agatacttat gaggaaacaa tgcatttcat ggatcaaatc aatcaattac tcggtcgttt
    12841 ttttatccaa gaactggata atcctgagac gatttccgaa acgattcgca gcttatttcc
    12901 ttattttcct gaaggactag taacggatga agaggtggtt catcgccggc tgcttaagcg
    12961 atatgaacaa gcacctatcg gtattcctca tacaaatatg gggttattcc atacatccag
    13021 ctcattgatt tctaaaccga tcttttgtat tttcaatttg aaacatccgt tgaccattga
    13081 agggatggat agacagccag tcgatttgtc ccgtatgtta gttatgctgg cgccttcgcc
    13141 aatccaagaa aaagacggga ttcttttagg aaagatcagt ggagcaatca tcatgaatga
    13201 cttgaacacc gagatcttcc gctcaggaaa taaagaaatc gtttatcagt tgttagcgaa
    13261 aatcctgatt gaagaaataa agaaatgaag gtgaaaagat gatacagcta ccagcagaaa
    13321 aaatattgct cgatcaatcc tatcaaaatt ggaaagaagc gttgaccgag atcggccagt
    13381 ggatgaccca acaaggggga atcaaaccgg catatatcca atcaatgatc gaaagacaag
    13441 aaaaagcgag tgtctatatc gggaatttcg tagccttgcc acatgggact gacaaagatg
    13501 aagaagtagt agaagaagga atctatttag tccaagtgcc tgatggtgtg gactttggaa
    13561 caaaagagga accaaaaatc gcgacactct tatttgtagt ggctttaaaa aaagaacatc
    13621 agttagcggt gctccaagat ttagcctttt tctgttcaga catcgaccaa gtaatggcgc
    13681 tcagtgatgc ggaaaccatt gaagaagtcc aaatgatttt tgaacatgga catatataac
    13741 caatgttcac agtaaaaaaa gctgccttgc atcaagtaat aacttcaacc aagataaaaa
    13801 taagaggagc tatttttgtt gggaggttct tattactgcg gatgcaagct tttgaaaact
    13861 atttattcta gaaaaccgtt tatttgaaat aggggacggt gacaaggttt ttgtcaccgc
    13921 ccctattatt tttgtgtttt aatagctctt ttttatatag atagtgccca tacctatgaa
    13981 taataaaacg atactccata taccaagtgt caagatacca ttcatgaaag taacctgttc
    14041 tgaagctagt ggcgagaaaa tatctcctcc tatgatcaca ttttgaaaat caacataaga
    14101 agttggcaag taatgactga ttgattctat ccatccaatc gaagaaaaca agcgatactc
    14161 tgctaagaaa agacaaagaa gtgtacctaa aagattgact agagaatgtt caaataaagc
    14221 agatagaaga aaactgattg tacttaaaaa gagcacccac aacaacagga acagaaagct
    14281 ctggaaaaga tactcataca tcggcaggat tcgtatctcc tgaccaatga tcgttcctac
    14341 aggataacgg aagtctccca aaccattttt gattattact agtatagaga cgatcaaaaa
    14401 tggcatcacg agacttagca tagctgcacc ataataaatg gtaaaacgga tgctatgttt
    14461 ctttaccata ctatccggta atagattgac tagagagatt acctgctttc ttttttcata
    14521 agagatgatg gaagaaagaa acaaggcggt tatacataaa atcaaaaaac tagaaatcat
    14581 tcctgaaaaa atattttcgt agtaatttgc taaagagaga tgcgctggca agtcaaaaat
    14641 agaatatctt tggatctgat gttctttcat ataacggagc aactcgacac gtttttgttg
    14701 ttcaatgatt ggaattcctt gtctttgacc agaaatcagt cgatccagta tatctttttc
    14761 ataatgataa gttgcttcga ccatttgctg gacattccct gtgttttttg catgtaagat
    14821 tgcttcgatc agtttgttgc ttttctctaa actttccaca aattctttct cattctcatc
    14881 ttctttcaac gtttcaatca aacgttgcat ctcttcatag ttatgattca gttcatcgaa
    14941 ttctgtataa gcaagtttat gatcaaaaaa aagtgggaat gcaaagagca cgaccaacaa
    15001 tagaggaaat aaaaagttta ctttgttttt tagtaagaga ttgcgttcaa atgtaagtaa
    15061 agacatagtt acacctcata taatttacga taaatagcta aaatctcttc catatttgag
    15121 gattctgtga cgatttctcc attttttaga aaacatgctt tagaacaaat cgattggata
    15181 ttcgcgatag cgtgggaaga aagaagaatc gtcttcccct ctttctgcca ttgtctgatg
    15241 aggctattca agatatcaat acttcctggg tctaatccgt tcaacggttc atcgaataac
    15301 atgacagatg aatcactgat caagtaagca gcaagcaaga catgttgttt cattcctaga
    15361 gacatttttc caatcggcaa agtaaggtac tcagtcatct tcaatcgttg gaaaacagtt
    15421 tggcattcta ctttgctctg ccaatagtat ttgatcaaag tcaaataatc aacagccgat
    15481 agatagtcgg ataactgatt cgttgattct agaaaaaaga aagaccggcg ataatctgta
    15541 taagcagtag gagagatgtt gtgaagggac aattgatcat aagttgttgg cagcagttgg
    15601 gcaatgccat tcagcaaagt tgttttgcca aatccgttcg gggcaatcaa agcagctact
    15661 tctcctgatt ctactaaaag attcaattgt cgaatcacac gttttttacc acgtttcatg
    15721 ttcatgtttt tgatcagtaa tgtcatagat aggcctccaa tataaaattt aataacataa
    15781 tagaatggaa aacatctaaa ttaaatgcta acaaaagtta ttgtttgcat attataaaaa
    15841 aattaaaata acagttttat ttaaaattga agttttctga taccgaaatc tttttatttt
    15901 gctgacatac tcaaaccttt ggcacaaagt ttcgtgccaa agtacgacta tttctctttt
    15961 tagtaagcgg atacaattag agtatcaaaa ggagagaggg agagacaaaa tggaacggac
    16021 gattcccaaa aacaacattt cgctaaaagc gagggtacaa aaattaggca gtactttatc
    16081 aagcatggtc atgccaaata ttggagcact gattgcctgg ggtgtattaa cggctctatt
    16141 tatcccagat ggttatttac caaatgaggc tttcgctacc atggtaagcc caatgctaac
    16201 ttatctgatt cctttattga tcggttatac tggcggaaaa gtaattgctg gtgaccgcgg
    16261 atcagttgtt ggggcaattg caacgatggg tgtgattgtc ggaacagata ttccaatgat
    16321 gctaggcgcg atgatcatgg gacctcttgg tggatatgcc atcaagaaat ttgatcagct
    16381 attccaaaaa cggatcaaat ccggttttga aatgctagtc aataattttt cagcaggtct
    16441 tatcggtttt ggattagcgt tattaggttt ttctgcgatt ggtccagttg tcgatgcatt
    16501 gactcaagca atggcaaaag gtgtagagat cattttatct gcccatttga ttccattgac
    16561 aagtattttt attgaaccag caaaaatctt atttttgaat aatgcaatca atcatgggat
    16621 tttgacacca ttgggaactg aacaagtagc agaggctgga aaatctattc tattcttgct
    16681 tgaagcaaat cctggtccag gacttggcgt attacttgct tttactttgt ttggcaaagg
    16741 agcagcaaaa tcttcagcac caggagccat gatcattcac tttttaggcg ggatccatga
    16801 aatctatttt ccttacgtta tgatgaaacc gttattattc ttatcagtta taggcggagg
    16861 aatgtcagga agtttcattt tccaattgat ggatgctgga ctaagagcgc cagcttctcc
    16921 agggtcgatc attgcgattc tagcgatgac accgttcaat tcttaccttc ctgttatttt
    16981 gggcgtgatt gttgccgcag ctgtttcgtt tggtatttct gcagtaattt tgaaagcgga
    17041 tgcgaaagat acaaatgaag acttcgaaaa atctgttcaa gagacaaagg cagctaagca
    17101 agcttccaaa ggtgcccaag gtattcctca aggagctaca ttctctggcg tacaaaaaat
    17161 catttttgct tgtgatgcag gaatgggatc aagtgcgatg ggcgcttcga tcttgagaaa
    17221 aaaagtacag gaagcagact tgcctcaaac ggtgaccaat caagcaatca gccaactgac
    17281 agatgactcg aatacattga tcgttactca ggtcgaacta caagaaagag caaaacaaaa
    17341 agcaccgagc gcgcgttttg tctcagtaga aaactttttg aattcacctc gatatgatga
    17401 aatcattcaa gaattaagca gcaagcagaa aacatcagtt tctgaaattg agaatgagcc
    17461 agcagaagag tttctttcag caaacatcaa acaaatcaaa gagattctac ttgtccacga
    17521 tgatcgttcc ggatcagcaa caatggggat gaccgtgctc aaagatatat tagacaagaa
    17581 ccatttaact atcccgttaa gaaaagtcaa tatccaagat ttaaaagatg aacctgattc
    17641 actgatcgta gccaaagaaa gtttagcgga aaaagtacag atggctgcac ctcaatccat
    17701 tcatttatca gtcaacagca tggtcaatcc gcaaaaatac gaatcgattg cacaatattt
    17761 gaaacagaca gcttaaggga ggaaaacagc atgcaaagtt tgccattcga catgatcgag
    17821 ctcaatcgat cttttaaaac caaagaagaa gcgatccgct attgcggtca gatgcttgta
    17881 gaagcagggt gcgttgatga ggaatatatc gatgccatgg tagatagaga caaaatgtta
    17941 tctgtttata tggggaattt tatcgcgatt cctcatggaa cagatgaagc aaaaaaatat
    18001 gtgaaaaaat ccggcatctg tgtcgttcaa gtaccagatg gtgtagattt tggtaccgaa
    18061 gaagaagaaa agattgcgac tgttttgttc ggtattgcag gagtcggaga tgagcatttg
    18121 caacttgtac agcaaatcgc actttattgc agtgatatgg acaatgttgt ccagctagca
    18181 gacgcgctca gcaaagaaga agtaacggaa aatctagcaa ttgcttaagg agagagaaaa
    18241 atgagagcag tacattttgg tgcaggaaat atcggtcgag gatttattgg agaggttttg
    18301 gcagctaatg gatttgagat tactttcgta gatgtgaatc acacgatcat tgatgcttta
    18361 aatgaaagaa aagaatacga aatcgaatta gcagatgaat caaaagaaaa aatcactgta
    18421 aaaaatgtca aaggaatcaa caatcaaaca aatccagaaa aagtaatcca agaaatcgct
    18481 gaagcagatt tagttactac cgccattggc ccgaatatct taccttttat tgctgagttg
    18541 attgcaaaag gtatccaaga aagagaaaag gaaggaagca caacatcttt agatatcatt
    18601 gcctgtgaaa atatgattgg cggttcagca tttctagaaa aagaagtgta taaatatctt
    18661 ccggaaacat catttactga caaatatatc ggctttccaa atgcagcagt cgatcgaatc
    18721 gtcccattac aacaccatga agatccttta ttcgtccaag tggaaccttt caaagaatgg
    18781 gtcattgacg atagccaaag aaaaaataaa aaaatccaat taaaaggggt tttatatgta
    18841 gatgatctag aaccatatat cgaacgcaaa ctatttagtg tcaatactgg tcatgcgact
    18901 gtcgcttata caggtgcctt gttaggttac cagaccattg atgaagcaat gcaagatgcg
    18961 ttagttgtgg cacaattaaa atcagttttg caggaaacag gaagtttgct gattgccaaa
    19021 tgggggtttg atgcagagca gcatcatgcg tatattgaaa aaatcattca tcgcttccaa
    19081 aacaaaaata tctctgatgc gatcacacgt gtcgctcgga caccattacg taagttaggt
    19141 tatcaagaaa gatttacacg tccagtgaga gaactacaag aacataactt gacttgccca
    19201 catttgacgg caacaatggg gattattttt aattactatg atcctgaaga tgaacaaagc
    19261 cgtcaattgc atgaaatgaa gatccatgaa aacttggaac aattgattca agaagtcaca
    19321 ggaatcaatg atccgaaaac aatcgggaat atcaagcaaa acgtgaaccg ttatgccaag
    19381 caagtcgctt aaaataggat acgaaaaagg ggaatgtgac gaaatttttg tcacattccc
    19441 ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat tctttaccgt
    19501 aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt cttgcaagga
    19561 taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca gattggtctt
    19621 caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct tcacctaaga
    19681 aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct tcgttatgga
    19741 taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga tccagtgcac
    19801 tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc aattggtagc
    19861 caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa gaatctttct
    19921 ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg ccaaagaaaa
    19981 ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc gtatggcaag
    20041 aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta tcaccatatg
    20101 tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc acggttcatt
    20161 cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac agcagtgtaa
    20221 gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat tacttctggt
    20281 aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag acgtaaagtc
    20341 atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc ggcaaagttt
    20401 tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt ggcatttaat
    20461 aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac ttgattgata
    20521 cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt gatgacttct
    20581 tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc aggatcgaca
    20641 ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata cataccgcca
    20701 acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt gtccatccgt
    20761 accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt tggacagtaa
    20821 tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg acaatttgga
    20881 cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc atggtcaaag
    20941 ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga atcaccgtta
    21001 ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt ataggtcgta
    21061 tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa gaacagttct
    21121 ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag gacagcaaac
    21181 tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc ctgtaccata
    21241 ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat attgactgtt
    21301 aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg gtagtctttt
    21361 gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg taaacttgat
    21421 ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc aatcgcaaaa
    21481 tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat aaattcaact
    21541 aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa gaaaaggtta
    21601 cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa cagcttgaaa
    21661 caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat attcccattt
    21721 taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt ttcttttggc
    21781 acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag tgtagcaatc
    21841 gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc agttgttcca
    21901 aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt agcagataaa
    21961 aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac tgattttcgc
    22021 acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact tttgaggaag
    22081 gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc gcctacagaa
    22141 ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt gatttgaaaa
    22201 tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata aaacatcgaa
    22261 ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc caatagataa
    22321 atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa tttggtaaac
    22381 aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca ttcccggcac
    22441 tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat caggatcaag
    22501 aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa cccagagttc
    22561 gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca acgatcaaaa
    22621 tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg aaaccagatt
    22681 aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg ttgattcata
    22741 tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa aatgacaaaa
    22801 gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc cagcagtata
    22861 ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt cacactcact
    22921 gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg ttcgcgaaaa
    22981 atcggcatat aaaatagaac gagtgataag accgtcatca atatataata aaaaacgatg
    23041 atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg cagccttcga
    23101 aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct accagtatac
    23161 aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag ctttcgatta
    23221 aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag gaataacaaa
    23281 ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa ttatgataca
    23341 gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa gatattaata
    23401 catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca atatgcagag
    23461 atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt gcgaagatta
    23521 catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca tgttgcgcta
    23581 atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa ccatcttgaa
    23641 aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt agatcttgtt
    23701 gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac catctcgcca
    23761 aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat ttacgggaca
    23821 caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt gcaaatgtgc
    23881 aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc caagcagcaa
    23941 ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac atcaaccgta
    24001 gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat aaagaattta
    24061 tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa caagaataaa
    24121 tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc caatcgctgt
    24181 attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt ccagctaccg
    24241 tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt cagtctcgac
    24301 atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta catgggacga
    24361 tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa gcgaaacaag
    24421 taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa gtccggatac
    24481 aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca cgcaaaatga
    24541 tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa cgtataacca
    24601 gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt gcataaattc
    24661 cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat tttaagtgtg
    24721 attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca aaactatctt
    24781 caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt tttaaatgta
    24841 ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt tgtgaagtat
    24901 ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg aaattcgatc
    24961 gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca attgaaatta
    25021 gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga actcggtcgc
    25081 atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt caagaaaaca
    25141 ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga aaaagtaggg
    25201 accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt catcgtcggc
    25261 ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa attgattgca
    25321 aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag aagaagacat
    25381 tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta ttcggaataa
    25441 gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa gataagacga
    25501 acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa agtacaacga
    25561 agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt aagctgtgaa
    25621 agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt tattagctag
    25681 agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta cattaagtga
    25741 tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata ttattactac
    25801 aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta tgcctggaga
    25861 tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg atgaacctta
    25921 tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat atgcttatag
    25981 ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact ttgaatatac
    26041 tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa aagacagccg
    26101 aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc gttattggcc
    26161 tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac atgttttttg
    26221 tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac tttttttgca
    26281 atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt gttcataaat
    26341 agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt tttttccaat
    26401 cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact aatttgttca
    26461 ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc ataaagtttt
    26521 gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag gatgagatta
    26581 gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac atttttcaga
    26641 tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc atcggcaatg
    26701 atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc gcctccgtaa
    26761 tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc ttcgcgaata
    26821 atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga atcaaaaata
    26881 ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta ttatagcacg
    26941 tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga aagaatatgc
    27001 cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa atattactag
    27061 acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag gaatcaagta
    27121 aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc actctttcac
    27181 agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa aagactatca
    27241 tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag caaaacatta
    27301 caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg atcaaactat
    27361 ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt tatgggatga
    27421 atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa tagatttaat
    27481 actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca agtataatac
    27541 cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta agtatggcgc
    27601 aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg aagaacaaaa
    27661 taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag gcgttgtttc
    27721 aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag acgtatttga
    27781 cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag cgcaattctt
    27841 aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata ttccggttat
    27901 ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa aatatttatt
    27961 gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc acaaaaaagc
    28021 aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc aagtgcaaat
    28081 tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc catcaatgat
    28141 tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg ttatgaagag
    28201 cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt tatgcagctt
    28261 tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta taaagaagta
    28321 gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga tgaaatggct
    28381 gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt agaagaaaaa
    28441 atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat catggaaatc
    28501 cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt caatatgtac
    28561 caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa cgttaccgga
    28621 atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata ttcgaaatta
    28681 aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc gcaagggcgt
    28741 atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt agagatcgat
    28801 attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg cggacagcac
    28861 gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat cgttgttgct
    28921 atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat cttgcgtgct
    28981 cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa tcgaaaatca
    29041 gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc gcaaaatcgt
    29101 gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt agcagggaaa
    29161 ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact ggaagctatg
    29221 caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt ttttagagga
    29281 tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac aatggaaaaa
    29341 acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc ggttgatcga
    29401 aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag gatatgcaga
    29461 tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac cagaaacaga
    29521 ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag tgatagatat
    29581 tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa attggcatat
    29641 atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg ctcagaaaga
    29701 aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg atcagcaatt
    29761 tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac tgatggatga
    29821 aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg gattagctat
    29881 ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa agattttttt
    29941 agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag catttccaga
    30001 taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc aagtttatgg
    30061 ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa cacttatttg
    30121 acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg acaaatagat
    30181 tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat gtatgaaaaa
    30241 ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg caagaggcag
    30301 ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta tacggattgg
    30361 gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa gggagaccgc
    30421 aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag tatgtggaca
    30481 actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca ttaactttga
    30541 tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta tccacagctg
    30601 catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc ggtgttccgc
    30661 ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca gatcatgtat
    30721 atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg cgaattggtg
    30781 tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt ttacgaccag
    30841 gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct attgatcagc
    30901 atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa cactactcac
    30961 ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt caatgggcaa
    31021 aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat caagtgcgga
    31081 cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg gctaaaggat
    31141 tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg atttttgtac
    31201 aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa aaagcagcag
    31261 gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta gtatgataca
    31321 atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta atcgtaatag
    31381 aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg taggaaaata
    31441 aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt tgggctgcga
    31501 tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct gaaaactttg
    31561 tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac gcagaaggtt
    31621 atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa aatttagcga
    31681 ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct cactccggct
    31741 ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg atcttaggaa
    31801 tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc agtggcaaaa
    31861 cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat tataatgtgg
    31921 tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc agtgcttacg
    31981 gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc gcaaaactga
    32041 tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct aatccagttc
    32101 cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct cgaggcggca
    32161 tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta tttcctggta
    32221 ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc aaagaagcat
    32281 tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa gcaatggtca
    32341 aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat aatcatctga
    32401 tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc attttggaca
    32461 gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt ccattcaaaa
    32521 caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa gaagaagatg
    32581 ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat aacgctcaac
    32641 tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg cataaaaaat
    32701 aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc tgtttatttt
    32761 ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga ggtgtaattt
    32821 tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct cgttagaaaa
    32881 ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg aactagcacc
    32941 ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca aatattccgt
    33001 cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata ttcgtctcgt
    33061 acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg gagcaggctg
    33121 ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg ttcgtacgaa
    33181 ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc caacagcaat
    33241 tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa aaaatctgga
    33301 tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta cagtcatgac
    33361 gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt attatccagt
    33421 cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact attttttgac
    33481 aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag agcgtgctga
    33541 aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc cttcagcaat
    33601 gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg cgcgcaaact
    33661 tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc atgattttgt
    33721 catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat tatctacttc
    33781 ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt ttcaaaaacg
    33841 gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg ttttacaatt
    33901 aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa gtgatcgatc
    33961 atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga acaaaggttt
    34021 ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca cgggatatgc
    34081 cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa acgttgtctg
    34141 gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt gacggtatct
    34201 tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat gaagaaacat
    34261 tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt cagttgtttg
    34321 tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat gcattgaaag
    34381 aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag ggagtaaaag
    34441 ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat gaaaaattga
    34501 atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg tttggtacaa
    34561 aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt ttggtcattt
    34621 ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa aaaaccatcc
    34681 caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt aacgattact
    34741 acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat ctcaacaaca
    34801 gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg aattgtgaac
    34861 attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat agttgtatca
    34921 aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta taccacgttt
    34981 tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa tcagccaaat
    35041 agagtatata atttcttttg gataaggcca gcttagctca gttggtagag caacgcactc
    35101 gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa gacagatata
    35161 tcaaggattt ttaatccatt gatacatctg tctttttgtt taaaggaaat aaa
//
LOCUS       DARPZJ010000024        35017 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.025, whole genome shotgun sequence.
ACCESSION   DARPZJ010000024 DARPZJ010000000
VERSION     DARPZJ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.025"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(54..2651)
                     /gene="adhE"
                     /locus_tag="SLE23_001448"
                     /gene_synonym="adhC"
     CDS             complement(54..2651)
                     /gene="adhE"
                     /locus_tag="SLE23_001448"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEI8468360.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2956..3336)
                     /gene="yajC"
                     /locus_tag="SLE23_001449"
     CDS             complement(2956..3336)
                     /gene="yajC"
                     /locus_tag="SLE23_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEI8468361.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3433..4578)
                     /gene="tgt"
                     /locus_tag="SLE23_001450"
     CDS             complement(3433..4578)
                     /gene="tgt"
                     /locus_tag="SLE23_001450"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEI8468362.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4796..5494
                     /locus_tag="SLE23_001451"
     CDS             4796..5494
                     /locus_tag="SLE23_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEI8468363.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5662..8301)
                     /locus_tag="SLE23_001452"
     CDS             complement(5662..8301)
                     /locus_tag="SLE23_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8468364.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8920..9951)
                     /gene="queA"
                     /locus_tag="SLE23_001453"
     CDS             complement(8920..9951)
                     /gene="queA"
                     /locus_tag="SLE23_001453"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEI8468365.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10144..11319
                     /locus_tag="SLE23_001454"
     CDS             10144..11319
                     /locus_tag="SLE23_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8468366.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            11323..11964
                     /locus_tag="SLE23_001455"
     CDS             11323..11964
                     /locus_tag="SLE23_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468367.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            11961..12878
                     /locus_tag="SLE23_001456"
     CDS             11961..12878
                     /locus_tag="SLE23_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8468368.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            12875..13546
                     /locus_tag="SLE23_001457"
     CDS             12875..13546
                     /locus_tag="SLE23_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468369.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(14087..14575)
                     /locus_tag="SLE23_001458"
     CDS             complement(14087..14575)
                     /locus_tag="SLE23_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HEI8468370.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(14776..15042)
                     /locus_tag="SLE23_001459"
     CDS             complement(14776..15042)
                     /locus_tag="SLE23_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEI8468371.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(15042..15305)
                     /locus_tag="SLE23_001460"
     CDS             complement(15042..15305)
                     /locus_tag="SLE23_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8468372.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            15781..15966
                     /locus_tag="SLE23_001461"
     CDS             15781..15966
                     /locus_tag="SLE23_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEI8468373.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(16108..17931)
                     /locus_tag="SLE23_001462"
     CDS             complement(16108..17931)
                     /locus_tag="SLE23_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEI8468374.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(18529..21234)
                     /locus_tag="SLE23_001463"
     CDS             complement(18529..21234)
                     /locus_tag="SLE23_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEI8468375.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(21540..22487)
                     /locus_tag="SLE23_001464"
     CDS             complement(21540..22487)
                     /locus_tag="SLE23_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HEI8468376.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            22677..22946
                     /gene="rpsN"
                     /locus_tag="SLE23_001465"
     CDS             22677..22946
                     /gene="rpsN"
                     /locus_tag="SLE23_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEI8468377.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(23122..23484)
                     /locus_tag="SLE23_001466"
     CDS             complement(23122..23484)
                     /locus_tag="SLE23_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEI8468378.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(23495..24616)
                     /locus_tag="SLE23_001467"
     CDS             complement(23495..24616)
                     /locus_tag="SLE23_001467"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEI8468379.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(24632..24982)
                     /locus_tag="SLE23_001468"
     CDS             complement(24632..24982)
                     /locus_tag="SLE23_001468"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEI8468380.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(25112..26623)
                     /locus_tag="SLE23_001469"
     CDS             complement(25112..26623)
                     /locus_tag="SLE23_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEI8468381.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(26945..28297)
                     /locus_tag="SLE23_001470"
     CDS             complement(26945..28297)
                     /locus_tag="SLE23_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEI8468382.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(28450..29526)
                     /locus_tag="SLE23_001471"
     CDS             complement(28450..29526)
                     /locus_tag="SLE23_001471"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEI8468383.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            29722..31467
                     /locus_tag="SLE23_001472"
     CDS             29722..31467
                     /locus_tag="SLE23_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HEI8468384.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(31747..32184)
                     /locus_tag="SLE23_001473"
     CDS             complement(31747..32184)
                     /locus_tag="SLE23_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HEI8468385.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(32168..33541)
                     /locus_tag="SLE23_001474"
     CDS             complement(32168..33541)
                     /locus_tag="SLE23_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468386.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(33863..34351)
                     /locus_tag="SLE23_001475"
     CDS             complement(33863..34351)
                     /locus_tag="SLE23_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8468387.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(34373..34975)
                     /locus_tag="SLE23_001476"
     CDS             complement(34373..34975)
                     /locus_tag="SLE23_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEI8468388.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9919 a         7476 c         6466 g        11156 t
ORIGIN      
        1 ttccaagttc tttttcatct attttcttat cttttttcta cgctttcttt tgcttatccg
       61 ttgtaagcat caatgatgat ctgtttcaat tcagagatca atggttcttt cggattagct
      121 gtcgtacatt ggtcttcgta agctaattca gccatacggt ctacggttgt atctagtgtt
      181 tcttgtgtga ctccttgagc ttttagactc atgttgatgc cgacagattt tcctaattca
      241 taaacagccg ttgctaaagc ttcgactaat tcctctgttg tttcgccttt cagacctaag
      301 aattttgcga tatctgcgta atctgtatct gcacggaaat agtcatattt agggaacatc
      361 gcatgttttt gtggatcttt tgcattatag cggataatat gcggtaaaag aatcgcattt
      421 gtccgtccat gagggatccc gtattccccg ccgattttat gtgcgactga gtgacaaata
      481 cctaggaatg cgttagcaaa cgccatacca gccattgtag aagcgttgtg cattttttca
      541 cgtgattcca tatcaggtgt ttttactgat ttttctaaat agtcaaagac taacttgatt
      601 gcttgtaggc tcaatccacg tgtataatct gaagccatga ctgaaacata ggattcgatt
      661 gcatgtgtta acacatccat cccggtatct gctgtgacag atgctggaac tgacatgacg
      721 aattgaggat cgacgattgc gacatctggc gtcaatgcat aatctgctaa cggatatttc
      781 acatgtgttt cactgtcagt gatgaccgca aatggcgtta cttcagaacc agtccctgat
      841 gttgtcggga tacatacgaa ttgtgttttt tctggtttgt cgatcttata tgtccgttta
      901 cggatatcca agaatttttg ttttgcacca aagaaagatg tgtctgggtg ttcatagaac
      961 atccacattc ccttagctgc gtccattgca gaaccgcctc caagagcgat tactgtatct
     1021 ggcttgaagt ctgccatcag tttcgttcct gcgtatacgg tatttgtcga tgggttcggt
     1081 tcaacatctg agaagacttc gatcttcaca tcatttttac gtcgtgccaa tacttcacga
     1141 actgtatcgc agtaaccgaa ttggaccata ccagggtcac aaacgatcat gacacgttca
     1201 acgttttcca ttttctctaa gtacaataga gagttctttt caaagaagat ttttggcggt
     1261 aatttgaacc attgcatgtt atttctccgt ttcgctacag ttttgacatt gattaagttt
     1321 acagcagaga cgttacgaga aacagagttc ttaccataag aaccgcatcc caaagtcaat
     1381 gacggaatca tttcgttata gatatcaccg atgccgcctt ctgcagatgg tgtattcact
     1441 aaaatacgac aagctttcat tcgaagaccg aatttgacat gcaactcttc gttttctgaa
     1501 tggataactg ctgtatgtcc taatcctcca agattcaaca taccttcaca caaatcaaac
     1561 gcatggtccg tgttgttagc tttgatcatg gcaagaactg gagaaagttt ttctcttgat
     1621 agcggataat ctgggcctac gccttccaat tcagcaatca gcattttcgt tccttttggt
     1681 acactgattc ctgccaattt tgcgatttcc atcgcagaat gtccaacgat tgatggattg
     1741 accgcatatt ttccttcgtt catcactgca tcttctaatt tttgcaattc atctggtttt
     1801 acgatataaa cttggtgtgc ttggaattct gcttttactg ctgcatagat ttctttatcc
     1861 acgatcacag cttgttcaga agcacaaatc attccattat caaatgtttt cgaaacgatc
     1921 aaatcgttca ctgcacgttt aatttttgct gttttttcaa tataagctgg tacgttacct
     1981 ggacctacac ctaaagctgg ttttcctgta gagtaagcag acttgaccat tccagctcca
     2041 cctgtcgcta agacgatcgc gatacctgga tggttcatta gcatagaagt cgcttcgatc
     2101 gaaggatgtt cgatccattg gatacaattt tcaggagctc cggcagcgat agcagcatca
     2161 cgtaccactc gtgctgcttc tgcagaagat ttttgggcac ttggatggaa agcaaaaacg
     2221 attggatttc ttgttttcaa cgcgatcatt gatttgaaaa tcgttgtgga agtcggattc
     2281 gttgttggag ttactccgca aaccacaccg actggttcag caatttcaat caaccctttt
     2341 tggacatctt cattgatcac accaactgtt ttatcatgtt tgatattatg ccaaatatat
     2401 tcggacgcat acatattttt gattgcttta tcttcgtaaa caccgcggcc tgtttcctct
     2461 acagccatct tcgctaatgg catatgttga tccaaagctg ccattgccat ttcatgcacg
     2521 atatggtcta ctttttcttg atcaaagctt tccatttctt tcaatgctgc atttgctttt
     2581 tctgccaaat catcaatcat tgcttgtacg tcaattgtct tcgttttttc tttttctatt
     2641 actttagcca tcattatcct cctaatgggt catggttatt tgttaaataa ttcacatgta
     2701 tatcatacaa tatttatttt tctatgtaaa cacttttttg tgattttttt cacagttatt
     2761 tttaaatata aaattgcttt atttacaggt gtttgtatag aaaaatatat aaagttattt
     2821 attattattt atatgacaca cccgattatt caatattgag caatatatcc catgctctta
     2881 tctctttctt ttttgaataa aaaatgaggt aggacatctt tctgccctac ctcgtcttta
     2941 aataagcttt gatacttatt tttcttcctt ctcttctgtc tcttccagcg tttctgttgt
     3001 ttcagttttt acttcaactg tctcagctgg ttcttctgtt gtttcaacag tagtcgttgc
     3061 atcatttgtt acgacagtcc ctggtttgac cgttttgatt gctgcacgat cgtactcaag
     3121 gaagatccct tcgcagtcta aaacaactgt ccgtttgtca ttgtcgattt ctgaaacaac
     3181 tccatgtaat ccgccgatcg ttacgactga atcacctggt ttcatgctat ctaacaagtt
     3241 ttgacgttct tgctgttgtt tcttttgcga acgtgacata aaaaaccaca ttgctaatag
     3301 cgcgataaac atcacaagca ttggtaatgt tcccattttt ttcacctcac taattctgta
     3361 tctacaaaaa acactttagc agaaaaatgc tgataacact agttttttac ttaattttta
     3421 aaagattttc ctttagaagc tttttgcgtt ttctttattg aacccgtatt cttcaaaaaa
     3481 ggcttctcta aattcaagca aattatcatc catgattgct tgacgtactt gtttcattag
     3541 attcaacaag aagtataaat tgtggtaaga agtcaaacga atcccaaatg tttcatcaca
     3601 tttgatcaaa tggcggatat aggcacgtgt atagttttta catgtataac aatcacattt
     3661 ctcatcaatt ggacggaaat catgggcata tttcgcattt ttcactacta gacggccttg
     3721 agaagtcata catgtgccat ttcgagcgat tcgagtaggc aagacacagt caaacatgtc
     3781 tactccacgg ataacaccat cgatcaatga atcagcagca ccgacaccca tcaagtaacg
     3841 tggtttgttt tcggggatca acggtgtagt gaattctaat acacgattca tttctgattt
     3901 aggttccccg acagataacc cgccgattga gtaaccaggg aaatccatcc cgactagatc
     3961 tttcgcgctt tgacgacgaa gatcttcaaa ccctgctcct tggatgattc caaataatcc
     4021 ttgacggtct ggattagcat gagctttcaa tcctcgttct gcccatcgag acgtacgttc
     4081 tactgatttt ttcacgtagt cgtaactttc atcgaatggt ggacattcgt caaaactcat
     4141 catgatatca gagcccaatt tattttggat gttgattgct ttttctggtg ataaaaacat
     4201 acgcgaaccg ttcaagtgat ttttgaaatg cacgccttct tcttcgatat tccgcatatc
     4261 acttaatgaa aaaacttgaa agccgcctga atctgttaaa atcggttgat cccagttcat
     4321 aaatttatgc agtccgccag cttcttctac taagtcttca ccagggcgta gccataaatg
     4381 atatgtatta cttaaaataa cgccagcacc catttctttc aactcttctg gggacattgt
     4441 ttttactgta gctaatgttc ctactggcat gaacattggt gtggggaaag ttccgtgtgg
     4501 cgtgatcaat tcccctaaac gcgcgccagt atgtttttct ttcttgatta aacgatagcg
     4561 aatggcaggt tgcgtcattc atttccctac tttctatata aaatatcttg acaactccca
     4621 ccatcataat cgtttcaagt gctttttgca agttccctcg gcttccttct actttattta
     4681 atattctttt ttttatcctt tttttatgaa taacaaaaaa aagaaaaaca ttatgacaga
     4741 aatatttttt gatacatggt atattggtgt tattaaagaa aaggagggaa aaatcatgca
     4801 atcttctgca gaattaaaac gccaagcaaa agagagtcta aaaggacgtt ggggacaagc
     4861 tgttttacta aatctaatcc ctacattgat tggtattgct actattcttc ttattatgat
     4921 tcctattatc ttgtttgcca ccaccatata tgatggatca gcgagcgtct cagaagcgac
     4981 aacttcagga ggcggtagtt caggaggcgg tggcggaatt atttccagca tcattagcgc
     5041 tttgttcatg agcggtattt cttggactta tcttgatatt ttacgtggac aaaaagatca
     5101 gatcgaacca ttcaaagatg catttcgtgg attcaaaggt ttgtttatcg gcggagtgat
     5161 cagcttagct gtgctgatct cgatctttac aacattatgg ggtttgctat tagttattcc
     5221 tggaatcatt aaaagctatt cttattctca aagctatttt atttactacg atatcgtcca
     5281 agaaacagga caaacaccta aagtactgga tacgatcact gcaagtcgaa aattgatgga
     5341 tggttataaa ggacaacttt tctggttaga tctttcattt atcggctggc atatcttagc
     5401 attagcaact gctggtattg gttatctatg gctcagccca tacatttctg caacaaaagc
     5461 agcattttat gaacaattgc caaaagatat ttaaaagaga gtgtgacttg tgaccgaggg
     5521 ggtggcagga gaacaccgtt tatcgagagg cagtaaaaga aacattcagc ccattagcaa
     5581 aaaggaggtg tgacaacatt catgtcacac ctcctttttg tatagttcca gtaaaaagaa
     5641 aatcaactta gaaacagtta atcattcctc ttcttctgct tccggtaatc gatggaactt
     5701 gatcagttca ttcaccgcga ttggtacgat agataaaatc cctaccaaga accagtgatt
     5761 caaactgatg tgtactaggc cgaatagttc ttgcgtaaat ggcagcaaag caacagccgt
     5821 tgtaatagct aatgccagta acgccatttc taccaaagct ttattggtcg ctaaattgac
     5881 tttgaagatc gattggctgc tgcgtacatt gaacacatgc agaatcgatg aataagctaa
     5941 gatcaagaat gcaacagttt gaccgacatg ctgacttgcg tctacccatg ggctgatagt
     6001 atcgacataa ctacctaaat aataaccaaa caaggttacg atggtgaaga cccctgcatt
     6061 tatggcaatt ttttgcaata aacctcgagc aaagatccct tcatttttcg gaatgggtgg
     6121 ctgatccatg atgccgtgtt ccgctggctc tcttcctaaa gcaaatcctg gaagtccatc
     6181 agcaactaca ttgacaaaca gtagttgcac agctgtaaat ggtgctcccc atcctaacag
     6241 catcgcaatc aaaacaataa agatctccga aatattacag cttagcaaaa agttgatagc
     6301 tttacgaata ttctgataaa ccgaacgtcc ttgactgaca gcgtctacga tcgtcgcaaa
     6361 gttgtcatcc gtcaaaatca tatctgcggc actttgcgcc acatctgttc ctgtgatccc
     6421 catggcacac ccaacgttac ttgctttcaa cgctggtgca tcattcacac catccccagt
     6481 catcgctacg actgcacccg tacgttgcca agatttgacg atccggatct tgtcttctgg
     6541 cgttacccga gcatagacag agagagcttt gacacgcgca tctaattctt cgtctgataa
     6601 ttgatgcagt tctgatcctg aaagtgcttc tgacggatca ttcaagatac ctaattcttt
     6661 cgctatggca ctggcagtca ccacatgatc tccagtgatc atgactgttt tgatgccagc
     6721 ctttttcgct cgcttgattg ctcctttact ttctggacgt ggtggatcga tcattccgat
     6781 cagaccaatc aaacgtaagt ctttttccag tgcttcagaa gaaatatctt gcggttcttc
     6841 gtcataagta gcataaccaa cagcaatcac tctcagtgcc cgtttaccaa agcgatcatt
     6901 aacgatcgcc gcttgttcta catcgcctga actaaagcgc ggagcaagaa catcgaatgc
     6961 tcctttggtg attgagatgt atttttcgcc catttggtga actgttgtca tcatttttcg
     7021 ttcagaatca aaaggaagct cgtttactcg tggatatttt tcttctaatt ctgcctttgt
     7081 atgataattc tcttcaacag cccttacgat ggctacttct gttggattac ctttgataac
     7141 aaggtcgtca tcttcttgct cgaccgtcac atctgtacat agtgcagcca ttttcaatat
     7201 ttccatcgcg ctgttcgtca ttgaatcttc gatattcgtt acttcatctt ctttgctcca
     7261 tacccggcgg acgcgcattt cattttgtgt cagcgttcct gttttgtctg agcagataac
     7321 attagcggtt cctagcgttt caactgctgg caactgtcgg atgatcgcat gtttcctcgc
     7381 catcttctgc acaccgtatg caagtgtcaa cgtaacaata acagtcaagg tttccggtac
     7441 agctgcaaca gccaaggaaa tcgaagtcat gaacatctca aggagtggtt ctccttgcag
     7501 ttcaccaatc acaaatacta aagccgcagc cgctaaagcg atcatactga ttcgtttgcc
     7561 tagctgattc aatcggacct gtaaaggtgt tttttgcata gtattttcgt tcaaaagatc
     7621 cgcgatctta cccatttctg tagccatgcc aatggcagtg acgatcgctt tcccacgacc
     7681 tgcagcaacc gtacatcctt taaataccat attaagttgg tcacctaatg actcatcttc
     7741 ttcagcaata aatgctgcat ctttttcaac tgcttcactt tctccagtca acgccgattc
     7801 ttctacacgt aattgtgatg cttcgatcaa acgggcatcg gcagaaatag catcaccgga
     7861 ctctaaaaca agaatatcac ccactaccag ttgctctgac tcaacagtgg tcactttgcc
     7921 gtctcgtatg acagttgccg tttgtttatt catatcttgc aaggattcca gtgctttttc
     7981 tgcgtttcct tcttggacaa tcgccaatac cgagttgatc acaacgatag cgatgatcag
     8041 cagtccttca aataaatccc catgttctgt agcaaatgcg gtataaaagg aaatcaccgc
     8101 tgctacaaga aggatgatcg ttgtaaaatc ggacaagctt cgaaagaatt ttttgatcat
     8161 cgattctttc ggcgcctcat cgaatttatt caatccctgc ttttttcgcc gttcatccac
     8221 ttcttgtgaa gacaacccag tatctggatc tgcttctgtt accttcttta cttcttctat
     8281 tgtctgcttg tattcttcca tcctattcct cctttaaaat cttcgtacaa aaaaaggtac
     8341 ttattttact ataacatcct ttttttattt acttcaaata aagggcttat cgattatttg
     8401 ttaagaaagc gtaaaattta aagtgcttat atttgcaaac gctaccaaag gatgctatta
     8461 tatagatgta aggaaggagg ataccatcaa atagacagaa gaatttctcg atagaacagt
     8521 gtaagcaaac aaagttgtta gaagtacagg tttcacccag acatgcgtgt agagtacaaa
     8581 cctataaata gtgaatgcgt atggatgttt ggatcacgaa gtatccgaaa caagaagtaa
     8641 tgcgatacgt aacaattgaa taacgtaaac gtctgaaaat tgaataggaa caagagatgt
     8701 ttcaaatgtt gaagatgtaa cgaaaacaaa atttttgttt aacatgaaga aattcaacac
     8761 cgtgctttgc atgtatgatg gaaagttaca atcatttctg tttatttgaa tccttccgag
     8821 gtacaagaaa gccgagctta tcgagagctc ggctttttct ttgtcataaa atctttgtaa
     8881 agcttttttg ttattcaaaa ctagcggctt ttcataacct tatttcacga acatcgcatc
     8941 tccaaaacta aagaaacgat agcgctcttc aatcgcatgc tggtaagcag ataaagtcaa
     9001 ttctcttcct gcaaaggcac taactaacat gactaaagtc gattttggca aatggaaatt
     9061 agttgagaaa gcttctacca ctttgaattc atagccaggc gtaatgaaaa tatcagtcca
     9121 tccgctgtct gctttgattt ctccattaaa tttcgttcca atcgtttcta atgttcgaat
     9181 tgaagttgtt ccgacagcca cgattttccc gccattttta cgtacttggt tcaatcgctc
     9241 agccgcttct tccgtcaaac ggtagaattc actatgcata tggtgttctt caattttatc
     9301 tacgctgaca ggtcggaatg tacctaaccc tacatgtagt gtcagataga ctaattcaac
     9361 accctttgct tcgatctcat caagtaattc tttcgtaaaa tgcaatccag ctgttggcgc
     9421 tgcagcagaa ccattttctt tcgcatagac agtttgatag cgatctgggt cttccagacg
     9481 ttctttgata tatggaggca atggcatttc tcccaatgat tcaagaatct ctagaaaaat
     9541 tccttcatac tcaaagtcaa tgatccgtcc gccgtgttcc aattcttctt tcactactgc
     9601 ttgcaatctg ccatcaccaa aagagattct tgtcccaact ttggcacgtt tcgcaggttt
     9661 gatcaatgtc tcccacgtat ctccttgtgt attcgttaga agaaggactt ctaaatgcgc
     9721 accagtatct ggtttttctc catataaacg agcaggcaga actcgtgtat tattcataac
     9781 tagcgcatca ccaggctgta actcttcaat gatttcatgg aaatgtttat cttccatctc
     9841 tccagttttc cgatccaaaa caagtaaacg agaatgatcg cggtctttta atggtgtttg
     9901 tgcgattaat tcttccggca agtcaaaatc aaaatcttct gttgttaaca tatcgtcact
     9961 cactttctat catgtgcttc atcattctat catgtttttc gttctgttgg caaaatcagc
    10021 actttttcac ttctattttt tgttttccta aataaaaaaa ctaccctatt tgtatttttt
    10081 cattgtttta ggcatactag taatagatag ttcttcattg aaaatagaaa aagaggtggc
    10141 accatgattg aatttcaaaa tgtgtcaaaa atttataaag gtggaaaagt cgctgtagag
    10201 gacgtcaatc tttcatttga aaagggtgag ttcatttgtt ttatcggtac gagcggaagc
    10261 ggaaaaacga cgacgatgcg gatgatcaac cgaatgactg atccaacaca agggaaaatt
    10321 ttgattgatg gaaaatccat ccaagaaatt gatccagtgg aattgcgacg tcagatcggc
    10381 tatgttatcc aaagtattgg attgatgcct cacatgacga tccgtgaaaa tatcactctt
    10441 gtccaaaaat tgttgaaagt cagtcaagaa gaacggaata aaacagctga aaaaatgatt
    10501 gatcttgtgg aattgccccg tgagatgtta gatcgctacc cacatgaatt atctggtggt
    10561 cagcagcagc gtattggagt cgttcgtgcc cttgcagcga atcaagatat catcttgatg
    10621 gacgagccat tcggtgcgct tgatccaatc actcgtgatt ccttgcaaga ccttgtcaaa
    10681 gatttacaag agcgtttggg aaaaacgatc gtatttgtaa cccatgacat ggatgaagcg
    10741 attaaactag caagccgtat cgccatcatg agtgaaggcc gtgtgatcca atttgataca
    10801 ccagaaaata ttttacgtca tcctgcaaac gatttcgtag aagagttgat tggagaagat
    10861 cgcctactac aagccaagcc aaatgcgaca agagtcggcg aagttatgct aaatacagca
    10921 atcacgatta caccggaaaa atcattacaa gaagcaatca aactgatgag ggaaaaacgt
    10981 gtagatacgt tgttagttac cgataattcg aatgtattaa aaggatttat cgatgtagaa
    11041 acgttgaata aaaaacgagg aaaagtatcc agtgtcggcg acattttgaa taaacatgtt
    11101 ttttacgtaa aagaatccgc ctatcttcgt gataccttgc aacgcatttt aaaacgcggg
    11161 ctgaaatacg tgccggtcgt tgatgaacag aacaaagtcg taggtatcct gactcgtgca
    11221 tcattagtgg atatcgtcta cgatgtgatt tggggagaag atcccgcaac tactgatgtt
    11281 gcagagtcag ctactcctga agaatctaag gaggtctgac ctatgcagca gttttttcat
    11341 cagcacggtt cagaaattct ctcaaaaggt tttgaacatc tttatatttc aggacttgct
    11401 ttgatcattg gtatcatcat tgctgtaccg cttggtgtct tactgacacg ttttccaaaa
    11461 gctgccacga ttgtgattgg cttaaccagt gccttgcaga caatcccttc tcttgcttta
    11521 ttggcattga tgatcccgct atttggcgta ggtaaattac ctgcgattat cgcactcttt
    11581 atttattcat tattgccgat tttacgtaat acgtacattg ggatgaaaaa tgtcgattgg
    11641 aattatcggg atgtggcaaa aggcatgggg atgactgagt tccaatccat tttttccgtt
    11701 gaattgccca ttgctatgcc aacgatcatg gctggtattc gtttagctgc cgtttacgtg
    11761 attgcatggg ctacacttgc ctcttatatc ggcgctggtg gtttaggcga tttgattttt
    11821 agtggactga ataattacca accagatctc attttggcag gtacgatccc tgtaacaatt
    11881 ttagcactat tggctgattg gcttctaggt ctcttggaac accggctgac accgatcgca
    11941 cttagagagg agaatgaaga atgaaacgta tactaaaaat gaccatggtt cttttctctc
    12001 ttcttatact tgcgagttgt tccttccctg gtcttgccag caatacagat gaagacacca
    12061 tttcgatcac aggtggaatc acttcagaag cacagatctt agcaagtcta gttgccggaa
    12121 tggttgaaca ttatacagat aaaaataccg caatcatcaa caatctggct actacaacta
    12181 tcaaccatca agcgatgatg aacggagatg cttcaatttc agcggctcgc tacacaggaa
    12241 cagatttaac gactacattg aaccttcctc ctgaaaaaga tccgaaaaaa gcgtttgcta
    12301 ccgtgaaaga tgaatttgag aaaagatacg gtcaaacgtg gttcccgtcc tatggttttg
    12361 aaaatacgta tgtctttctt gttcgaaaag acaccgcaca aaaataccat ctatctaaag
    12421 tcagcgatct gaaaaatgta gcggatgaat tagtagctgg tgtagatact tcttggatca
    12481 atcgtaaagg agacggttat gacggcttcc aagaaactta tggcttctcc ttcaattcga
    12541 tattacctat gcagattgga cttgtttatg acgcagtcga agcaggaaaa atggatattg
    12601 ttcttggcta ctctacggat ggacggatcg ccagttatga tctagtcatg ttggaagatg
    12661 atcgtcaatt cttcccacca tatgatgctg ctccagttgt agacaacaag atattagctg
    12721 atacgcctca tttaaaagaa gccttaaata agttaggtca taccatcagt acggaaaaaa
    12781 tgcaggaatt gaactacgaa gcagataata atctagtgga accatcagta gtagcacaac
    12841 gtttcttaca agaaaaccac tattttgaag ggaagtgaag caattggata aaatgaatgt
    12901 ctttcaacaa tttttctatt atttccagga aaatggctcc tatatctttg cacaatttat
    12961 ccgtcacttc ctgatttcta tctatggtgt cctctttgca gcagttgtcg ggattccggt
    13021 tgggatcatg atttctagga gacgtaaatt agcaaactgg gtgattcgtt tggcgaatat
    13081 catccagacg atcccttctc tagccatgat ctccatttta atcattggat taggcctggg
    13141 agtcaatgtc gtgattgtta ctgtattttt gtattccctc ttaccgatca tcaagaatac
    13201 gtataccggg atgatccaag tagacaaaaa catccttgat gtcggcaaag gcatggggat
    13261 gactgctaga caacgactat tcatggtaga gttaccactc tctgtttctg ttatcatggc
    13321 aggcataaga aacgcgttag ttgttgccat cgggataacc gcgatcggtg cattcgtcgg
    13381 tgctggtggt cttggagata tcattatccg aggaaccaat gcaacagagg gcacatcgat
    13441 tattttagca ggtgcattgc caactgcatt aatggcgatc atcacggact ggcttttagg
    13501 tattttggaa agacggctag atccagccag ccgtacatca cgctgatgtt attgtaaaaa
    13561 acaaaagctt ctgcgaccat ttgttggtcg caaaggcttt tttagttctg tcatttttaa
    13621 ggcaataatc cactctgatt cttccctcct tatgggcaaa gagttgcttt tcttagctat
    13681 ttatccattc cgtatactcc aacttcatac tgccaacggg ttcatatctg catccaccga
    13741 ctaagttttt ttcttatccg ctaaggcatt ttgccaatcc attttcccat cactcgtcat
    13801 ggaattcata ccacatgatc tctaaatact cgtctgcttg ttctttgaat tgggcatcaa
    13861 ttcttacatc ctttggcgtg gctttcattt aagccttttc catcagtcct cgattgttcg
    13921 atgccttcag ctgcatcatc aaaactggtg actgccgtat cggtaacttc gatcatcttt
    13981 tatacaatcg ggaacttgcc atcctcatcc ttggctaaaa acatatctag ccattccagc
    14041 ttctcgccat gggaggtttg cggttcctaa aaccggtaca cgattcttat ggactgcatc
    14101 cgtcgcaact agacttggcg atacgatgat ccttcaccag aagagcaccc ccgtaaacca
    14161 attgatcgat atattgccaa taagaaaaga cattggcgta aaagatatcg atccctcgtg
    14221 atgcattgcc gttgatactg ctattcatgg ccgaaagcgc cacgacttta acttcttccg
    14281 tttgagtgac attcatgttc ggcaatgtcg ctttggatac ccgctctgct aaaggaacga
    14341 cactggtatt gtatttcgta tctgtatctt ttccaaaaga ccatgccaac gaatcctctg
    14401 ggaaccaata agacgactcc ggttgattgt ccattgcttt tttcaacata cttttggctg
    14461 tttctcgata aacgacattt ccaattgtct tcgcctcact ttggcgataa tcgatggtcg
    14521 ttgccactgc caacactaac aacgatgctc caattttact gattttcctt gtcacacttc
    14581 ttcctccttg ttttacataa acccgtcaac attccattcc taaactcaaa caatgaccct
    14641 tcaaaggtgg agatatagga acaaattaaa gaaatcatgc aataaatcca agaaggttgg
    14701 ttttagaaca aaaaaagagt ctcctttttg gggagactct ttgttaacta tctaaaaagg
    14761 ttggctcttc tcacttcact cataatgtgt ccaggcagaa taaatttcta caactttatt
    14821 ttcctcatca actttgtaaa ccactcgatg ctgtctattc agcctgcgtg agtatctgcc
    14881 ttcatgtgta ggtctcagct tttcaaaaga ctgcgtgggc atatatggat cttccttcaa
    14941 tgtctgaatc acttcttcaa attgtttctt taaattcgtt tgcttgattt ttcttaaatc
    15001 cactttcgca gagtttttga ttgcgactgt atagttactc atcaaagagc ttcccaatca
    15061 atatcatcga tattcgtaaa gctactgtcg tctttttcgc ggtctcgtac tttatctaaa
    15121 gtacctgttt gctcaagaaa aagggtttct tgaatcgctc tccagtcttc cagcccaatc
    15181 aatacagcat tgtttccact acgatcacta ataatctcga tttcagtatg attttcattt
    15241 acctctttca ataactgata aaaattttta cgagcagtgc taggattcat cgttgtatta
    15301 gccattgtct ctcctccttt ttctgatata attatagcgt acttgattaa gtacgtcaaa
    15361 aaaatacaat aaagcactta aattcagcaa acttttcctc ttttttacat agagaaaaag
    15421 accccttttt agggaggatc tttgtccacg ctcacttctt actcctttac gactagcggt
    15481 agccaaacgt aaagtaattg gtaacaacgt atcatcttta gcaaaggtcg aatccaaagc
    15541 ctgtgagtct atgcaacaac accaatacac gaaggttcct cgttgcagtg tgacttgatt
    15601 gatatcttga ataacctgag gatacgcacg aaagatttgt aacggttatt caaaactgat
    15661 tttggccgtc aagtcttcta ctgcctcaaa aatgattgcc tctttcgtct cctgtcattc
    15721 atgttcacta tcgatttgat acttgcttag accgttgggt ttgtgaatca ccaattaaaa
    15781 atggcactga gttatggtaa caaaaaatgg tcacttgacg aggctgagat tcctacttat
    15841 gaagacacat ggcacttaag agtcgaggta aaggaagaag ctgaaaatat aggaggctgt
    15901 acattatttg gcaaaggatt cggaaattat gatcaagaca tcaaaatcaa aatgttttac
    15961 agctaaatag gaagaataat aacatttcat acgctgttcc catctttaat ggcttataga
    16021 gggcaccttt agctgagaat aagacaaaac agaccctcta gcttcaatta agagctagag
    16081 ggtctgtttt tgattttaaa acttggttta tttcttcaaa tggtagctat aggtgctgac
    16141 aacgatattt tcacgccaag acaatcgcaa tcttaaccgc aaacttgttt ggttatggag
    16201 aatattctgc cagcgtctgt ttggtacaaa ttgaggaatc aacacagtag ttgtatagtt
    16261 ttgtttcgct gcatttttac ttacgatatc tacataacgg ataattggat tttcaatcga
    16321 gcgataagaa gagtggacga ttgaaaaacg gacatctggg aaatgctttt taaattctgc
    16381 ttcgatttct ttttcttttt cgacatcttc gtctagcgaa acatgcatcg caacgacata
    16441 atcaccgatc gaacgtgcgt aattcaacgc accgatattt acccgtgtca cattcccgac
    16501 taatacaaga acggtattcc cgtcataatc atgtagtttt gcatcatttt ctaaacgaag
    16561 ctgttctgct acttttttat aatgatcatg gatcttataa aaaatgaaca taacgattgg
    16621 cataatgatg aagaaaggcc aaatgtcccc taaccgatag acaaacaaaa tcgcaatgat
    16681 tgcatatgag atgaacgcac ccgtaatatt ggcaatcgat ttgcttaacc atctttttcc
    16741 ttcttttttc catttgacga ccatccctgt ttgagataaa gcaaatggaa tgaacacgcc
    16801 gatagagtat aacggaatca agcgttctgt tgagccatgg aaaataaaca gcaatacgat
    16861 cgaacctagc gctagtgtga taatcccatt ggaatagcct agtcgatccc cacgatcttg
    16921 atacatgtga ggcatgaatt tatcttttgc cagattgtat gcaagaactg gaaaagcaga
    16981 aaaaccggtg ttagcagcaa ctgctaaaat cagcgctgta gcaaattgaa ggacgtaata
    17041 caaaatacca tgtccaaaga cagctttacc aatttgagac aaaacagtga cttctttttc
    17101 aggaacgatc ccataccaat agttgataaa tgtgatcccc acgaagaaga aacctaagat
    17161 caatgccatc atcgtcaatg tagcagcggc attttttgct cttggcttct taaagaatgg
    17221 tacagcatta ctaatcgcct ccaccccagt taaagaggaa gaaccagaag aaaatgctcg
    17281 taaaatcaaa gcgatagaaa cacccggcac agccgctcct ggaagtgcag tagcttgcaa
    17341 tggcacagca cctgtcacga tattatataa accaacaacg atcagtaacg agatcacaag
    17401 gataaatgtg tacaccggaa ataataggaa cgatgcagat tccctcagcc cacgaagatt
    17461 cagcatcatc agtagcaaaa cgattgtcac agaaatagcg acttgatgac cgtagagtgc
    17521 tggcaccgct gatgtgatcg cttcagcacc tgctgagaca gatactgcta ctgtcaacat
    17581 gtagtcgatc aataaagagc caccggaaat caagccagca ttctttccaa gattctcact
    17641 gctgacgaca tatgctcccc cgccatgagg ataagcatgg atgatttgac gatatgatag
    17701 cgttaatgaa atcaataaaa taataacaaa agcggcaatg ggtagcgaat accagatggc
    17761 tgcagcagac aaagcgacta aaacgacaac gatttgttcc gtaccatatg caatagatga
    17821 taacgcatca gacgacaata atgccaaagc agcaaatcgg gttaatttgt gctcatcatt
    17881 ttcagcagat tttaaaggct tacctactaa caaccttttt aagtaatcca atttctaaac
    17941 tcctttacac acaattttac ttcaagtttt atagtcgaaa atttatagta aacaagatgt
    18001 tatagtacgc tcactgacct taaaagtcaa taaactttaa gaaaataatt ggaaaaaaac
    18061 agaaaaatat caagcgcttt ttcaaacgct ttaatacagc aaaaatctaa cattttttta
    18121 tgggcttttt ctttgaattc tataataaaa ggatagaact tgacttagaa aatcaagttc
    18181 tatccttttt gatatcttaa cttttggaag agagatgtaa ggctgctttc tacccatcat
    18241 tcttactact cgaagcatag cgcagttgtc acaacctctt gataaacggt gtttaaaagc
    18301 ttgcatctgc ggtaataagc tcaaccaaat taaaaacata agaagctgtt tttatttggt
    18361 cgttcttatt acttgatgca gagcagcttt tttacaacct cttggtacac ggtgttcaat
    18421 cagctgaccc tcggtattag ctcaaaaaaa cggcaaaata tgaggaacta tttttccatt
    18481 tttttctcta atactcaggt caaaacactg atttcacaac ctcttttttt aatgaaaaat
    18541 atggctctca tgcgccgctt ctttgaattt cgtcattttt tcttcgatga acggatagat
    18601 tgccgttcct acgattccaa agacaacaaa caaaccgatc atgatccaga ttgctttcgt
    18661 agcatttggc caataaattc ctcctgcaga ttcccgtaac aagtttaccg catgagtaaa
    18721 tggcaagaac ggattgatca tttggaagaa tttccctgag acttggatcg gatagttccc
    18781 gcctccgcca gagatcgaca gtactaagat gataatagcg atccctttac cgacattatc
    18841 gaataatgca gccaagacat agacgatcat catgaacgct aaggcgatca agacagcaaa
    18901 tgacacgctg tagaccggat tttggacatc tactcctagt aagaaaatat tccctaatgt
    18961 aacgatcaag ctttgcgcaa tcgccattgt caaaaatgtc agcatacgag caacgaattg
    19021 ttctcgtttc gtaaaattgt ttcggtcttt ctttcctaaa tagtattctg tcgtagcaac
    19081 acttgaaaga agaacagcgc cgacccacag acatagtgca gtataaaacg gggtgctagc
    19141 tgaaccgtta tttgcgattg gataaagcgc attggtttgt agctcaacag gttgtgtaaa
    19201 gaagtcactt tcttttgttg cgtctagttt caataatttg atgacttcgc ctagatcgac
    19261 ttcttgttcg ccttttcgga tcgcgtctgc tgctttttgg ataccagctt tgatatttgg
    19321 ccagtcattg ttgatcaagt ccgcagcagc gttcacagct gtttcgactt ctggcatttt
    19381 ttcatttact gttgtcaatg taccggtgat ttcatttttt agtgctggcc aatcattttg
    19441 gataaaatca gcggccaatc ctaatttttg ctgaatgatc ggtaattcat tgttgtatag
    19501 gtctgcccct tcattgatgc cattgacgat ggtatccata tttccattca gcattgtatt
    19561 ggcatcatgg atttcttgtc caattgcagg catttctttt tgatattttt ctaaaattgc
    19621 cactgcattc gttacagttg ctttcgttga gctgagaagc gaatcaaagt cgatctggtc
    19681 cgctttgctc agtgcgcctt gtgcagtccc aatcgtatcg atgacttggt ctagtagaga
    19741 agtgacagtg gaactgattt gacctgtatt gataccagca atgatgccat tgatattatt
    19801 aacaacggca tcaatttgat ctagcaattc atcaatagcc ttcgtgtctt cattttgaac
    19861 agctgtgttc aaagcagata ggcggttttg cagattgctt agcaagggtt ttaattgatt
    19921 tagctgatca ataattggct gtaatttcgt atttccagca cttgtttgca atttagtcag
    19981 gaactcgacc agtttatcga ttgcattttg ttgttgagat attccgtcaa taaagccgtt
    20041 caatacattg ctgatgtttt tcttttcatc atcagtcagc ttaccatctt caatagctgt
    20101 tcttacagta tctattaacg aacctgtcgt tgttgccact tgtccaattg acttcaatgt
    20161 aacatctaca ctgtttgtga tgcttggtat cgcatctttc agctgagagg cacctgattt
    20221 tgtttggttt gctagatcac ttgcctgatt ttctaaattt ttcacatctg gcaagatatc
    20281 ttgtacttgt tggatgatcg tcaagccttg ttttgcttca tcgattcctt ggttcattgt
    20341 ctcttggatc gaagcaaaat cgccgtcgat ctctgctagt tgcttaccgg cattttggat
    20401 ctctgggatt ttttcttgca aatcaaggat gatttttgct tgatctttca actcaggcat
    20461 tttgtcattc aatgcaacga ctttttcacc catctcatct actttaggga tgtaatccac
    20521 gaattcattt gctttattca gtttttcctt gatttcaggt agttgacttt gtaattcgag
    20581 gacttgtttt gtgtagccgt cgatcgtgtc caaattttca tctgttgata aaatcatatc
    20641 tttaacttta ttgatactta ctaggttcgt atcgatgtcg taacctatct cattgaatac
    20701 tttcaataaa gtcgaactgg ctgttttgat aaattcattt gtgatttgcg attggatcga
    20761 acttgctcct ttatcggtga ttttcggtgc aatcgcattg attttttcat ttaccgtata
    20821 ttcgattttt ggtttcttga tatcaccact agtaaaactc agcagatctt ctgagaaatc
    20881 ctttggcaag taaatacctg cgtaatactt tccggaacgg actccgtctt ctaattgttc
    20941 ttttgaatca acgaattgcc atcctaattg tttattttta tgaagcgatt cgatgacttg
    21001 ctccccaatg gccacttctt taccttgaaa ctctgctggc ttgtctgcac tgtaaacagc
    21061 aattggcagc tctccagtat ttccatatgg atcccataat gctttgatgt taaaccacgc
    21121 atatagcgaa gggatgatca tgatcgcgat gatcagaagt gttgcaatcg ggtttttgaa
    21181 aatccgtttc cagtcaagca aatataatcg aagcgtattt ttgattgact gcatagttct
    21241 cccccttctt cttttttcag ctgaattact ttaccatgta tttcatactt ttttcaatcg
    21301 gcttttttca aaaaagtcga atttttggac atatcacggc aattgtctca ttgtaatctc
    21361 ttacatattg agaaataatt aaggattaca gcctttactt tatcatgaaa taaaagggaa
    21421 agataatttt atgccaaagt ttttatctat tatacgtata cgcaaaaaag ctaaaacatt
    21481 ttttgtcttt gcccctacaa aaatgtttca gcttttttcg ttttttattc ctgtatttct
    21541 tatttttcga atgacaggat gattttccca gcaggaggat gtccttcaac tagctgatgt
    21601 gcttggatga catgcttaag tgaagcagac agattcattg aaataaaaac atgaaaggct
    21661 cctttttggt aggctttgat tatgccagca aaggcttctg catctagata ttcctttctt
    21721 ggaacaaacg attcataaaa gccttccttt ttttgccgca aatctagatc tgggaggtca
    21781 tttaatgcaa catacctgcc gcctggtttc atgatctgga tgccggtttc tcctttgata
    21841 cttcctttcg tcgcatcgat tacaaggtct gcctgatcag caaattgcag acctggattt
    21901 gttttatcat aagcagcaaa tgctgaagct cctaattttt ttaccttttc ctcattttta
    21961 ctggatgcac tggttaagat tcggattccc ttttcatgga gaagctggat cagacttgac
    22021 ccgaccgcac ctgatgctcc tagtatcatt acagtatctg tcggctggat ttccgtcaaa
    22081 tggttgatta gattataagc cgtaattcct ggcgtgacca ttccggctgc ttcttcccaa
    22141 ctcattttat ctggaatttt tgctactttt gctgatggca acacgacttc ttctccgtaa
    22201 gtcccgccga ctgcatggac agctactcga tcacctacat gaacagttgt gacatctgaa
    22261 ccaatctctg tcacaatacc agcgccatca ttacctggta cataagggaa tttcaatgtt
    22321 cgtatctctt tcatttctcc taaacgcaag gcaacatcat aaggattcac actgaatgct
    22381 tttatttcta cacgaacatg tccagaaccg acttctctgg gatgagcatc gatttcttca
    22441 aaaacatctt gtgcttctcc gtaaccgtta attgcaaatc ttcgcatggt caccatctcc
    22501 ctttttcttt aagtttacgt ttatgtcttt attttgacaa aaaaaatgtc ttttcgtttt
    22561 ggcgcatgat tcaaaacaaa atagttgtct tttttcgcgt aacgtgttaa attatttatc
    22621 taaaagcgta aagattacga tttacgctaa taaaaaataa ttggaggaat ttgttgatgg
    22681 ctaaaaaatc aaagattgcc aaagcaaaaa aacagcaaga aacgattgaa cgctatgctg
    22741 ctttacgcca ggaattaaaa gcgcaaaaag attacgaagg cttgcgtaaa cttcctttag
    22801 atgctcgtcc agaacgattg aaaaatcgtg atttaatcga tggacgccct cgcggataca
    22861 tgcgtaaatt cgggatgtcc cgtataaaat tccgtgaatt agcacataaa ggtttgattc
    22921 caggagtaaa aaaagccagc tggtaatcca agtctggctg taatgtaaag gaggagggcg
    22981 catggaccac tccttggatc atcaaaaaag atacgttcgc ttcttctagc agaaatgctg
    23041 gtactagaag cagacgtatc tttttttacg cacagctggt ccttttttat atgtaaaggc
    23101 tgcatggtta cttcgctata tttatttagt aacaggagtc agtgcttcga tacccacact
    23161 aattttcaat gctcggtcaa cttctgccat aatgggtcga tccaaatggc agaccttttc
    23221 tttcaatctt gatttatcga tcgttctgat ctgctccaac aggataacgg agtctctttc
    23281 tattcctgtt ccagtagctt tgatcccaat gtgagtcgga agcttaggtt tagccatttt
    23341 tgccgttatg gccgcaacaa tgatcgtcgg gctaaaatgg ttacctagat tattttgaat
    23401 aaccaaaact gggcgtgttc cgccttgctc cgatcccacg actggagaaa gatcagcaaa
    23461 ataaatatct cctcttttta ccataggatc ctccttattc ttgatattct cttggtatcc
    23521 gctgtcctaa tccgcaagcc acttcatagt ggatcgtacc taattgatct gctatatcct
    23581 gcatagtgat ttctttgtct gcatttttgc cgataagcgt cacttttgtt ccgacaggaa
    23641 attcttgagg caatcggatc atcagttgat ccatacatac acgcccaatc gtttcacagt
    23701 agttcccttc taccaataga gaaaaaccct gcatctttcg tggccagcca tctgcataac
    23761 cgatcggtat cgttccgatc cactctgctt caggagtgat atatgtttct ccatagccga
    23821 ttccttcacc tgctgggagt tttttgactt gaatcaattc agaaaccagc tcaagtgctg
    23881 gctgcaatgg ataaacttcc ggtagtgcgt gcccagaggg attaagtccg tacattgcta
    23941 ctccataacg aatcatattg ccgattgttt catcatgcca taaagccgtt gcactattgc
    24001 tgacatgtac atatcgagga agttcgggaa gttttttcag cacttctata aagcgttctt
    24061 tttgcagatt ccaatatgta tcatctgcct gatctgctgt agaaaaatgg gtaaataaac
    24121 cttcccattc taatacacga ctttctttga tgaatgcagc tgcctctttt acttcttcag
    24181 gtgtacaaaa tccgatacga cccatcccag tgtctgcttt tagatgaatc gaaagaggcg
    24241 tctctagctt acttttctct aaaacagcag ctgctgcttg caaccattcc cgtgtacctg
    24301 cagttactga taaatcatga gcaacagcta cagtcagtgc gtcgtaagga accatattca
    24361 agataaggat gggctgagta aatccagctt ctctcaactc gactccttca tctaaatttg
    24421 aaacacaaaa gcccgaagct ccacctgcaa ctgctgcctc agctgtttca atagctccat
    24481 gaccgtatcc gttcgctttt actactgcaa acaattcttt tccttgcgga agtcttgcaa
    24541 cttcatttgc tacattttca gttatagctt ttttatgtat cactgctttc gttgggcggt
    24601 gccaagcgac aaccatcgtt tttccttctt tctagtcttc caaaataatt tgtgcaaaag
    24661 ctgtttcatt tgtatgagta atactgaccc atacattgcc ttcatgaggt gaacgcgtca
    24721 caacaggctg accattttca ttttttaaaa tctcgacatc ttgaaaggta acttttccga
    24781 tcccagttcc ccaagcttta gagaaagcct ctttgcaagc gtaacgcccg cctaaaaatt
    24841 ctacttggcg atgaaaaggc aaggactgga atagtttcat ttcatcagag gtcaagattc
    24901 gtgcaatgaa ttttggtttt tcttcgatca gccgagtgat cctaggaagt tcgactgcat
    24961 cgatcccaat tccttttatc atatgctttt ctcttttcaa taaatttaga acactctcat
    25021 tctaccaaat tataaccatt ttgccacaaa taagtccaca aataacaaaa atgaaagttt
    25081 ctcttaaaaa agagaaactt tcattttatg tttaatcgtt atttgaacgg attacaaatc
    25141 cgcgtttttt atcattgtga cgtttaccgc catctttttg gctgttatta tttttgctat
    25201 aaccgccttt tgatttgttt ccacgataat taccgccgtc acgacgatta cggttgtttc
    25261 cgccaccacg tttgccattt ttattgtatc cttttttctg cattggcaat gggcgttctg
    25321 gtgtgatctt cactggcact gcatcagctg gatcttttgc tgtcgttttt agcaaaagtg
    25381 caactaaatc ttgtgcagaa tattcttcta ataatttatc tgctgtttgc aggtatttat
    25441 ctagaccatt ttctgcaagt tttgtttcga tttgttcaac tgcagcacct aattgacctt
    25501 tgaatgcttc tttttcggtt ggtggacgta aagtcgtcat ccgttttttc gtcaagtttt
    25561 caatcacatg caagtagtcc atttcatttg gtgtaacgaa agtcacagac ataccgcctt
    25621 ttccggcacg gcctgtacgt ccgatacggt gaacgtagct ttctggatct tgagggatat
    25681 catagttgta cacatgagtg acacctgaaa tatctaatcc acgtgcagca acgtctgtcg
    25741 ctacaaggat atctaaatga ccgctcttaa atgaacgcaa tacgctcatt cgtttttgtt
    25801 gagacaaatc gccatggatt ccttctgcac ggtaaccgcg tgcttctaat ccgcgtgcca
    25861 attcgtctac acggcgtttt gtacgtccga agacgattgt taattcaggt gtttgaacat
    25921 caaacaagcg agtcatgata tcgaattttt cgtattcttt tgcgcggaca tagtattgat
    25981 cgatcaagtc agctgtcatt tctttcgctt tgatcttcac atgatgtgga tttttcatga
    26041 atttaacgcc aatattcttg atagctggcg gcatcgttgc tgagaaaagt aatgtttgtc
    26101 tttgatcagg aacttgtgaa atgatttttt cgatatcttc caagaagccc atattcaaca
    26161 tttcatctgc ttcatccaaa actaatgttt gaacggttcc aagtttcaat gtgtggcggt
    26221 taatgtggtc aagcatacgt cctggtgtac ccacaacgat atgtggacga tctttcaagc
    26281 cacggatctg acggccaata tctgctccgc cgtaaacggc ttgtacacgt acttttttgt
    26341 cgcgccctaa acgatataat tcttcttgtg tttggatagc taattcacgt gttggtgcga
    26401 taactaaacc ttgtaattcg tgacgatctg gatcgatttt ttctaacatt ggtaatccaa
    26461 atgcagctgt tttccctgta cctgtctgtg cttgtccaat aacgtctttt ccagctaatg
    26521 ctagtggaat cgtttctgct tggataggcg ttgcttcttc aaaaccagcg cgttcgactg
    26581 atttcaacaa ttctggtgat aattctagtt ctttaaattt caaatgaatc ctcctatatg
    26641 gttgttaact gaggatgtag cttttttgct accccgtcga tttgttcggt caaagtgtat
    26701 tgtttctttt tgacagtggc cacgcacgtt tttatccatt cttagcccct gtggcaccac
    26761 cgaaaaatca ctttgcgaag tttaggcatt agaaaagcca aacgggtcgc gttcagcttt
    26821 atcattatta tgacatctgg cttcaacaag ttgtttctat ggcaaaacca gtccaatttc
    26881 tcttcatctt tcggcaatag gttattctaa catagttttt cgttttctgc aagtttacag
    26941 atttttattt catttgctga agttgttcta ccacttcaaa taagcccatg ctgttgctgc
    27001 cttttagcat aatactatct gttgctgcaa gattttgttt gatagcatca atcaatttat
    27061 tcttttcttt ttcaaaatag aacacaggta gttgggggta tttttggttc aattcttctt
    27121 ttagtgcatg catttgttcc ccataaagga aaatcatggc gaatttctca ggatcgatat
    27181 gttcactcat ttgcgcatgc atatttaaag actctttccc taattccagc atatctgcta
    27241 acacagcgat tctgcgtcct tttgttggca gatttttaaa agtatctaat accagtccca
    27301 tggctgttgg atttgcattg tagacatcgc tcaaaatagc tgcaccattt cctgccgtta
    27361 gccattcggt tctgttttga gtgatagaaa catgggcgag cccttggcgt atctcaggta
    27421 tggacagtcc aaagaagcgc ccgatcgtat acgcaatcaa agcattcgtt acattataac
    27481 ttccaggcag cgggatcgta aatgtttctc cttctactac aaaatcggtt tgtgcttttc
    27541 cttttgctgt cacttccgca tgaacatcgc catttccaat accgaatgtt gtgactgttt
    27601 gtactaatgt tgccgttaaa ggtgtcagca acggttcatc tgcgggcaca acgagtaatc
    27661 cgtctgatac aagtccgtca gtgatttcca ttttggcttt agcgattcct tctcgcgacc
    27721 caagattttc tatgtgtgct tcaccgatca ttgtgattgc tgcagctttt ggttgagcca
    27781 taagtgaaag ttccgtgatt tcattggcgt gatccatgcc catttccaaa acgatctttt
    27841 ctgtatcttg gggcatgtgc aaaatcgtgt aaggaagacc aatattattg ttgtaatttc
    27901 cttgcgtctt atatgttttg tatttttcag acaagacaga cgcggttaga tctttcgtgg
    27961 tggttttacc attgcttcct gtaattgcaa cgacttctgc gcctactttt tccaagtaat
    28021 aggttgccaa ttgctgcatg gctttcaaag gatctgctac aggaataact ggaaaatttt
    28081 ttggagcttg ttcaacaggc aagctccaaa atgaagcaga tgctccgttt gtgatcgctt
    28141 gctggataaa ttcatgtcca tctcgcgtac cagcaagagg aacgaataaa cttccttcgg
    28201 ttatcttccg gctgtcaaat tcgacattgg taatctttgt cagtgcagag cattcgctgc
    28261 ccacggcttg tgcaatttct tgtattgtta gattcattga gatctctcct aaaaaaggtt
    28321 gtgaaaaaag cgtttggcct aaacggcggg ttcgcatgac tctcacttcc aagtaaattt
    28381 ctctattcgt atttagaagc tagaatgaac gcggttacgc aatcactcca gcctcttctt
    28441 tatttctctt tattcatttt tttcaaaaaa agattgacgc tgatggtatc gattcattcc
    28501 taactggatc agttcttcaa tcaaatcacc gtatttcaag cccatatttt cccataagag
    28561 tgggtacata ctgaactccg taaatcctgg catagagttt aattcattca ggaataattc
    28621 atttttattt gtcaaaaaga aatcgcaccg gctcaatccg cttccaccta acatcgtgta
    28681 agctaacttc gcgtactctt gcgctttttg ataaacttct tctggcactt cggctggaat
    28741 ctgcatttcg attttattat tgatatattt tgcttcataa tcatagaatg ctacgtcttt
    28801 tacgacttca ccaggcaaag tcgtccgaac gtcttcattt cctaatacag caacttcgat
    28861 ttcgcgcgct tcaattcctt gttcaacgat tgctcgagaa tcatactgat aggctgttgc
    28921 taaagcattt tgcagctctt ctcggttttc tgcttttgta atgccgacac tagaacccat
    28981 attcgccggt ttgacaaaca tcggataaag caaagaacct tcacattgat caaatacttt
    29041 tttaggattt tctttccatt gattcttaag tactggtaca taaggaactt gcggcacacc
    29101 agcagcttgt aaaatatact tggtcatgat tttatccatg gcacatgcac tggtcaatac
    29161 gcctgcgccg acataaggca tattcaatgt ctctaagaag ccttggatcg ttccatcttc
    29221 cccgtttggc ccatgtaaaa ctggaaaaac gatggctcct tcttctttga tttcgcccgg
    29281 attgatcact tttcctgtaa agccttcctc tgtctgtcca cttgggtccc atgaaagatg
    29341 caagacatct ttgctggcag gtttttctgt tagtaatgga cctttgaccc attgtccttc
    29401 ttttgtaata aatacgagtt gaacttggta ataattataa taaatggcat ttaaaactga
    29461 aaatgcggaa agaatggaca cttcatgctc tgcgctgcgt ccgccatata gtaaagtaat
    29521 cttcaaaaga ttgtcctcct gtattctaaa tcgttcagtg atttactctc atattttagc
    29581 acaaaacaaa aataaacgaa taacttattt ataaaaaaac gagccagctt ctaaaagaac
    29641 gagcgtcatt tattttttgt cagctagatt atttgtcccg ttttttataa aaagttatga
    29701 taaagaaaag gagggatgat gatggcgcaa acaaatccac gcagccgctt ggcagaaatc
    29761 attcgagtgt tcatcaatta caatgtagtg ccaaactttg tacagcaaaa aaatcccgaa
    29821 caggtaaaaa aagcctttga agaactaggc cccaccttca tcaagatagg acagatgctt
    29881 tctgttcgag aagatttgct ttcttctgcc ttcactcaaa cattcaaaac attacaagat
    29941 agtgtaccta gcgacacatt ttcaacggtc aaaaagacga tcgaaacaga actttctctt
    30001 tcattatcag atatattcga tgatttttca aaatcgcctt ttgcctctgc ttctatgggg
    30061 caggctcatc gtgccaagct gaagaacggt gacgcggtag tcgttaagat ccaacaccct
    30121 aacatcgccg aagagatccg acttgatctt caactatttg aacgagcgat ccctttgatc
    30181 aaatacattc ctgaaactag cgtagttgat ctaaaagggg tactccaaga agtaaaacgt
    30241 tccttgatca atgaaatgga cttcttaaaa gaaagtcaaa atggcgaaca attctatcaa
    30301 aagaacaatg gctggaaaga gatccgcagc cccaagattt atgacgcttt ttgttcgaaa
    30361 aaagtgatcg tgatggaaga aatgtctggt aaaaacttga atcatttaat gaacgccgaa
    30421 aacaaaactg aaacttttat cactggaatt caaaacaagc agctgaaaca agaagttgca
    30481 aagcttttag ttgagaactt tatgaaacag gtgtttgatg atggtttttt ccatgctgat
    30541 cctcatccag ggaatctgct attccatgta ctaacaaaag aagaacagac acaagctagc
    30601 cgaaaaactg aaacagtcca tgaaaaagag ttcggttcct ttgcttttcg agcctccact
    30661 tctgcagaag accctgttgc gccatatacc atcaactaca tcgattttgg tatgatgggg
    30721 catctttctg caggacttag gcaaaaactc acacaagccg ttttagcgct gtatacgaaa
    30781 gatgcttatc gaatcgaaaa agcggtcctt cgactttgtc agcaagaagg ctcgtttgat
    30841 gaaagtcggt tccaccaaga actgacaagt tttcttgaac agtattatga ttctcctatt
    30901 gatgaaatca acttgcaaga agtattcaca catgtcgtga cgatttgtca tcaaaataat
    30961 ctgcagttcg atcgtgatat cacgcttttg ctgaaagcat ttgggacatt agaaggggtg
    31021 atccgcgtcc tcgatcctga agtttccctc atggaagtcg cttcgccttt tgctcaacat
    31081 tattttctca ctcatctgga tgtagaagat acattgaaac aaagcggatt agacttattg
    31141 gaagggatga aggctgcgcc taagatccct caacagctcc accatctatt agaaatgtgg
    31201 acttcgggac aaggaaaagt caatttggaa ttgaaaaagc aagacaaatt attgagcagg
    31261 atcgaaagta tgatcaatcg gcttgttttc ggtatgattt tagctgcatt gatcgtaggg
    31321 tcctccctgc ttgtccaagc agcacctgta gaaaacgcag aggtcgtttc cttattaggg
    31381 atatttacgt atgctattgc cgcattcgtc attatttttt tggcaatcga tgcattgatc
    31441 caaatgtata agaagaggaa aaagtagaaa aaggttgtga cagaaagaat cagcttcaag
    31501 aaataagaag gggttttaca taaattgttt ctcaaatttt tgtgaaaatt cggcttattt
    31561 ttcgaagagg ctacttctga aacaccgaga ataaaaaatg tgaaaaagct gttctgcacc
    31621 cagtaataag aacaatcaaa aagggaacat ggaacacatt tatcctgttt ccctgttccc
    31681 tttttgatgt attcgagcat aaataaaata ccttcgttac ctactatctt ctgtacttgg
    31741 taaaccttag tcaattgcct tttttaacgc ttgacgaaaa gacatatgat ctttctccgt
    31801 aaagggtttt ggaccctttg tccttatgcc agcttttctt aactttccac tatgataacg
    31861 ttgttctaga agcgtgccga tattcgcttc gtcaaattct tttccagagt gatggaacac
    31921 tcgcacaccc ttcggcaata caagtgaagc taaaccataa tcttgcgtga tcaaaaagtc
    31981 attcttctta accataccga cgattttata atccgcacta tcagctccgc ggtctacgta
    32041 gacgatttgg acatgattag cgtattcttt ggtcgtataa tggtccacac tggtcacgat
    32101 aaccacgtca agaccatagg attctcctaa ttttatgaca tcttctttta ctggagaacc
    32161 atctccatca atgaatagcc tcattctttt tcgccttctt ccataaatga taaacagtta
    32221 ctaatccgct cagtaaaaga ccaacattga tccattttgc caagataagc agttgtacac
    32281 tttctatcgg cactgattca tggttcagcg tgatcaataa tagatggatt ggctctccca
    32341 tttcttttgc taaaacaaac aaaagcgtca tcaataaaaa ctggtggatc acactccctt
    32401 tattttgagt agtatacttg acaacgatcc ggcgatccat tggaatagct gtatcagttt
    32461 gataatattc cttatttagc cagctgcctg ttactacgtg ccagaaacta agcagaaaga
    32521 cacctatcgc aaaaccattt ggaatcaaga ggaccaataa agaagaactc agtccaagca
    32581 attgcatagc caatggagac catgttaaac gtttcaaaat ccatggtccg actatttttg
    32641 ctgcaatcaa gcctgctgca taaggcaaat acataaaaat cgaaagtttt tctaatccgt
    32701 acagtatgcc aacataaaaa ctgctaaata aaaaaaggaa attccctagc attccattta
    32761 gaaaagtaaa cagatttagc cagcttggca acttccattc cttcttctgg tgtcctaaaa
    32821 caaacacgaa caagatgaac agcagcaaga aaccataaat agcaagatca aaaagccttt
    32881 catcgaataa caatcgggca tttctcaaaa gaaacaataa gccaaagaat atcaaaaata
    32941 aaacaagctc tcgcgtagct accagatttc ttttgatgtc tttgaaatcc agttcgtaac
    33001 gcggataatg actaaccgta tggtaggcca tgacgtaaaa aagtgtataa atagtaaagc
    33061 ttgctgcaat ctgagtcggt gcaggcaact caatcgcttg atacaggaga aatagccaga
    33121 tagctgcaaa taagtacttt ttcccatcca tattgataaa accttgcgtc ttttcgtgaa
    33181 aattgaccgt ggtattagca ggtacaagcc atgctgcact cagccctagc aaaacacttg
    33241 aaaaataaaa taaaggaaaa taaaatacgc ctaatattcc aagcaatgaa ccagcaccac
    33301 caatcagcag agcgatcatc agcaacgtgt aactatctag accaaatcgt agactgttga
    33361 ctaaaaatag tccagtcatc cgaaaggcat aaaacagcgt aaatggcaaa atcgtcagcc
    33421 aattatgcga gtctgttagt cccaaaaata aaagataagg aataaaaata accgtgttac
    33481 ttaagataaa gggcgttgtt tgtgtaaaat tacgcccaaa tcgtttgagt ttttcgaaca
    33541 tgacaatggc tccttaaaca gtcttataac taatctgctc ttcgatttta gcattaaagg
    33601 ggaaataaac caattttaca gaatatattc ttgtaaaaaa aaatacagaa agaagcataa
    33661 gcttctttct gcatttttac ggtacttgat tactcaagca gacaagccct tctccacaaa
    33721 agtcttgccc gacacccctg catccggcag gtgataaaga tagaaatcaa ttatcctgtg
    33781 cctccaaaat caattaggag ctctgtaaac cagagtcctt ctcgacccgt cgcataaatt
    33841 tactttaaca cagttcctat gtttatgcga gagctttttt cattttataa tcgaccattt
    33901 gaaatccttg accgatatct gaaataagtt cttctgtaat ctcaaatcct tcatgcttat
    33961 aaacctcgat tgcttgatga ttcccctgat tcactcgcaa aaagatctct ctttcctttg
    34021 tttgcgcagc aagttcttca taccagcgaa aaactgaaga agtcaatcct tgaccacgta
    34081 ctttatttag caaatataat ttacttaaat aaatttttcc atttatctct tcataagcag
    34141 tgtaaccgac agtcttttct tcgcttttta ataaaaagta ggacacacct tctgtcagtt
    34201 ctttttgaat ctgttttttt gactgataag ttttcagcat gtaatccact tgtttttgac
    34261 caatgatcgg cacaaaagct tccggccata cttcttgtat gactgccatc agctcatcca
    34321 gttcattttc tgttactttt attttttcca tacacccacg tcctttttta cattataaat
    34381 gaccttgcgc ttgatggaat aaaaagagca tgatcatgct atacacaccc accgaccatg
    34441 gtttcaagaa aatcacaatc tgcataaatt ccctaaaaga taatttcgtc aaaccagcta
    34501 ctagacagat caagtcgtct ggcgcaaagg gaagcagcaa ggtaacaact agtacttttt
    34561 taatatcttt cgtttttctt gtcagcaatt catcaaattt ctgatacttt tttggcgata
    34621 aaataagctg gacaaaggct acgccatagt aacggacaag caaaaatccg attgcttccc
    34681 caatcactag gccaatacaa ctatataaaa gcccaaatcc attgccaaac atcagcatgc
    34741 ccgctactga ggagatccct cccggcaaaa taggaatgat cacttggatc acttgcaaca
    34801 gaacaaatat catcactgca tacttgccaa attgctggat aaacgcttgc aaagacgtgc
    34861 tcgatcgaaa aatcccatga tgataagcat aaagaatcaa cacaaagaaa aaaaacagac
    34921 caataatggg catgatctga agacattttt gtaaaactga tcctttttta gacatctata
    34981 ttccccacat cttttttcat ttattaaaac tgcctcc
//
LOCUS       DARPZJ010000025        34522 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.026, whole genome shotgun sequence.
ACCESSION   DARPZJ010000025 DARPZJ010000000
VERSION     DARPZJ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.026"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(133..306)
                     /locus_tag="SLE23_001477"
     CDS             complement(133..306)
                     /locus_tag="SLE23_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8468389.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="SLE23_001478"
                     /pseudo
     CDS             754..3116
                     /locus_tag="SLE23_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="SLE23_001479"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="SLE23_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEI8468390.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="SLE23_001480"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="SLE23_001480"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HEI8468391.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     VQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="SLE23_001481"
     CDS             5704..6489
                     /locus_tag="SLE23_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8468392.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="SLE23_001482"
     CDS             6502..7353
                     /locus_tag="SLE23_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HEI8468393.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="SLE23_001483"
     CDS             complement(7477..7929)
                     /locus_tag="SLE23_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468394.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8394..8762)
                     /locus_tag="SLE23_001484"
     CDS             complement(8394..8762)
                     /locus_tag="SLE23_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HEI8468395.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8912..9394
                     /locus_tag="SLE23_001485"
     CDS             8912..9394
                     /locus_tag="SLE23_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HEI8468396.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9431..10441
                     /locus_tag="SLE23_001486"
     CDS             9431..10441
                     /locus_tag="SLE23_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEI8468397.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10556..11269)
                     /locus_tag="SLE23_001487"
     CDS             complement(10556..11269)
                     /locus_tag="SLE23_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468398.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11459..12049)
                     /locus_tag="SLE23_001488"
     CDS             complement(11459..12049)
                     /locus_tag="SLE23_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HEI8468399.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12533..12760
                     /locus_tag="SLE23_001489"
     CDS             12533..12760
                     /locus_tag="SLE23_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEI8468400.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12776..13942
                     /locus_tag="SLE23_001490"
     CDS             12776..13942
                     /locus_tag="SLE23_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEI8468401.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            14176..15219
                     /gene="hrcA"
                     /locus_tag="SLE23_001491"
     CDS             14176..15219
                     /gene="hrcA"
                     /locus_tag="SLE23_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEI8468402.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15313..15876
                     /gene="grpE"
                     /locus_tag="SLE23_001492"
     CDS             15313..15876
                     /gene="grpE"
                     /locus_tag="SLE23_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEI8468403.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15927..17756
                     /gene="dnaK"
                     /locus_tag="SLE23_001493"
     CDS             15927..17756
                     /gene="dnaK"
                     /locus_tag="SLE23_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEI8468404.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17907..19073
                     /gene="dnaJ"
                     /locus_tag="SLE23_001494"
     CDS             17907..19073
                     /gene="dnaJ"
                     /locus_tag="SLE23_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEI8468405.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19155..19820)
                     /locus_tag="SLE23_001495"
     CDS             complement(19155..19820)
                     /locus_tag="SLE23_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468406.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            19796..19969
                     /locus_tag="SLE23_001496"
     CDS             19796..19969
                     /locus_tag="SLE23_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468407.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(20014..20751)
                     /locus_tag="SLE23_001497"
     CDS             complement(20014..20751)
                     /locus_tag="SLE23_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8468408.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(20753..22255)
                     /locus_tag="SLE23_001498"
     CDS             complement(20753..22255)
                     /locus_tag="SLE23_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEI8468409.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            22514..24508
                     /gene="uvrB"
                     /locus_tag="SLE23_001499"
     CDS             22514..24508
                     /gene="uvrB"
                     /locus_tag="SLE23_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HEI8468410.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            24518..27334
                     /gene="uvrA"
                     /locus_tag="SLE23_001500"
     CDS             24518..27334
                     /gene="uvrA"
                     /locus_tag="SLE23_001500"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEI8468411.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            27597..28862
                     /locus_tag="SLE23_001501"
     CDS             27597..28862
                     /locus_tag="SLE23_001501"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HEI8468412.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            28866..29597
                     /locus_tag="SLE23_001502"
     CDS             28866..29597
                     /locus_tag="SLE23_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HEI8468413.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            29732..30616
                     /gene="rapZ"
                     /locus_tag="SLE23_001503"
     CDS             29732..30616
                     /gene="rapZ"
                     /locus_tag="SLE23_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEI8468414.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            30613..31611
                     /locus_tag="SLE23_001504"
     CDS             30613..31611
                     /locus_tag="SLE23_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEI8468415.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            31645..32580
                     /gene="whiA"
                     /locus_tag="SLE23_001505"
     CDS             31645..32580
                     /gene="whiA"
                     /locus_tag="SLE23_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEI8468416.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            33123..33773
                     /locus_tag="SLE23_001506"
     CDS             33123..33773
                     /locus_tag="SLE23_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468417.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            33960..>34522
                     /locus_tag="SLE23_001507"
     CDS             33960..>34522
                     /locus_tag="SLE23_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HEI8468418.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        11453 a         5831 c         7324 g         9914 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgtacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaat
     8101 atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg tattttttcc
     8161 ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt agaaaattca
     8221 aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa aatagcagat
     8281 actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga acaaaacctg
     8341 tataaggtga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa gctttatcgc
     8401 caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg ttcaatcaat
     8461 tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata tacgtagcct
     8521 gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc gatagaaaaa
     8581 tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa cataggttgg
     8641 ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc aaaaaggtct
     8701 ttgatctttt gttgatgttc tttttctttg atttgattga tgatcggctg aaatttttcc
     8761 attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca atagttatgt
     8821 ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg ataagatgtc
     8881 tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca
     8941 cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt
     9001 ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga
     9061 taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc
     9121 attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca
     9181 aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat
     9241 tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca
     9301 aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat
     9361 atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag
     9421 gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc
     9481 accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat
     9541 ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa
     9601 atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat
     9661 ccaaatgatc tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga
     9721 ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact
     9781 tgctgtcaca ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag
     9841 aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg
     9901 agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc
     9961 atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc
    10021 agtaaggatg aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg
    10081 tactccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt
    10141 gtggtttcta gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat
    10201 gaaactggca ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga
    10261 ggatttgtta gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact
    10321 accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg
    10381 tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta
    10441 aaaaattttt tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag
    10501 tgaaagaagc tgacaaaatg ctgtcagctt ctttttgtat aacatattag aaagtctaat
    10561 tatctataac tgtcacatcg attaactgtt tcacgtcatt gggatttcct gtaggaatag
    10621 ctactacaga tgcattatca atgatttctt gagttgtttc tctaatgaac gctggataag
    10681 atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg ataactagtg attgtcccgt
    10741 catggttact tgaatacact aaaactccct ggtaactgta tttcccagtg agcataacca
    10801 catctttcgg atagactgca ctccctgcat cataaggggc gataggtgtt cctgcaggat
    10861 aatgaataac atgtaattcg aaatcacccg atgtatctct aaaagtatta cctctaatag
    10921 ctagccaaac acgtgcgtac tcaatttgta gatcagaata tcctgctaac ggatctattg
    10981 actgagaaga ctgtgaggag gttgtgtcta ttgttgaaga agaaatattt gtctcaactg
    11041 tactactaga tgtagaagaa gtattgggct ctgagacttt actgcttgtt gaagatgtat
    11101 tcgtttcagt agaagctgat ttctgagtac ttgatttttc agctgaactg gtttgtctga
    11161 ttgaactttt gtctgtggtc gcagatggat cactattttc tttactagga gacgtacatc
    11221 ctacaaggaa taaagagacc aacaataaaa taaaacctaa ctttttcata taaaatacct
    11281 cattattttt ttaataccag tatagcataa tcctgaattt ttgaatccgt aaaaccttgt
    11341 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
    11401 tcatcagtaa aattacttgt cacactattg ataaggagta tttaattgaa gagaatgatt
    11461 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
    11521 tcgttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
    11581 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
    11641 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
    11701 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
    11761 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
    11821 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
    11881 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
    11941 tagaagcagt tttgttttgc catttctcat tttggtttag tgtgctagta atataagcac
    12001 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
    12061 cctttactat ctataacaag gacaacagtt ttaacctaca gacattcatt aaaattgggt
    12121 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagata gtcaacttaa
    12181 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
    12241 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tattaaaaga
    12301 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
    12361 tgaaaacaac cctagagata tataactagg taaccagttt aatgaaagaa aaaatcatcc
    12421 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
    12481 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
    12541 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
    12601 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
    12661 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
    12721 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
    12781 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
    12841 gcatatctgc tattactgtg attttaataa agttttttta gaagggcagc cagtagatga
    12901 gtatgtggaa atgctgctga atgaaatgaa aataatgcta gaaagtcatc cgacagcgaa
    12961 tttagaaaca ctttacgtag ggggcgggac accaacttct ttatctgcta aacaacttga
    13021 tcgactgtta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
    13081 agaagcgaat ccaggtgatt tgacccgtga aaaacttcaa gtaatgaaaa actatggcgt
    13141 caatcgttta tccatgggag tgcagacatt tgataatcgc ttattgaaaa aaattggacg
    13201 taaacacacc gcagaagatg tgtatcaaac tatgcaattt ttagaagcag aaaattttac
    13261 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatctgga
    13321 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
    13381 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
    13441 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
    13501 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
    13561 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
    13621 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
    13681 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
    13741 aggactaaga aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac
    13801 aattgaatcg gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa
    13861 tgaagaagac cgtgtttatt tgacaccaag agggaccttt ttggggaaca atgtgtttga
    13921 gcgctttttg tttgaaaaat agtttaaaga atatttgttt tttatctgaa tttaaataaa
    13981 aaaagttcaa aaatacaata aaggactatt gaaacgttga tataactgga tttacatcaa
    14041 ttatttagaa ttagcactct tgtgtttaga gtgctaaaaa atggagtctt tctcttgaca
    14101 ggagaagggc ttcttgctat atttataagt ggattagcac ttagaatata tgagtgctaa
    14161 tgagaggtga ggaagatgtt aacaaagcga caaaacgaca ttttacgtct gatcatccaa
    14221 cactatacga gtagtggcgt gcccgttggt tccaaaacat tgatgtctga gggagtcaag
    14281 gccagctcag caacgattcg caatgatatg aaagcattag aagatgaagg attgctgttg
    14341 aagactcact cttcttctgg gcggattcca tctgctttag gctatcgtta ttacgtggat
    14401 catttgttaa aacctgctcg cgtagcagaa gatgatttgc tgctgattcg tcagtctcta
    14461 ggcagagaat ttcatgaaat caatgagatt attaagcaat ctgctgagat attatctgag
    14521 ctgacaagct atacgacttt ttcattggga cctgaaataa aagaccgccg actgactggc
    14581 tttcgtatcg tacccttgaa taatcgacag attattgcta tcgtcgtaac agatatgggg
    14641 aatgtagaaa gccaagtgtt cactcttccc gaatatatgg gaagtcagga actagaaaaa
    14701 atggtacaga ttgtaaacga ccgtctagtc ggagatcctc tgatgacggt gtaccataaa
    14761 cttcgtacgg agattccgat gattcttcat aaatatttcc aaacgacaga agggatgtct
    14821 cagttatttg acaccgttct tggtcatgtt tttgaagata aggtttatgt cagtggacaa
    14881 atgaatctct tggattatga gccccgtcaa gatcttgatc agttcaaatc gatgttttct
    14941 tttatgaaag actcagacgg acttacacaa atgatcactc cgatggatag caatattcat
    15001 atcaagattg gtgctgaatt aggcaatgat ttattgcaga atatgagtat gattcaagca
    15061 agttacgaga tagatggtca tggaagaggt acaatagcct tgttagggcc tactagtatg
    15121 ccttattctc ggatgttcgg tctagtcgat gtttatcgaa gagaactagc agctaaactt
    15181 gctgattact accgttcgct tgacttgtca aactcgtaat gtgaataacg aagctatttg
    15241 cagctgatcg ttctctcttt cttagtaaga gcaatcaaac agctgactga ataatgaaag
    15301 gaagactgta tcgtgaaaga aaatcaagaa gaactagata aagaaatgac agatgctcag
    15361 ccagaaccgg aaatcgatgt cgaagctgca gaagattcgg gtatttcaga agctgaagcg
    15421 gaagaattcg aaacagcgaa attaaaagct gagttagaag aaatggaaga taaatacttg
    15481 cgggctcgtg ctgaaatcgc aaatatggca aatcgaggaa aaaatgagcg tgagcaatta
    15541 caaaaatacc gttcacaaga tttagccaaa aaattacttc catcaattga caacctggaa
    15601 cgtgcattag ccacagaagt gtcagatgat caaggggcag gtttgaaaaa aggcgtggaa
    15661 atggtcttgg aaagtttgcg taacgcactg gaagaagaag gaattgaaaa aatccctgct
    15721 aaaggagaag cctttgatcc taatcttcat caagcagtac aaactgttcc agcgactgaa
    15781 gatacaccag ccgatacgat tgtagaagta ctacaagaag gctacaaatt acatgatcgc
    15841 gtgttaagac caaccatggt cattgttgca caataattgt gcggatataa aacttacact
    15901 ttcaattaaa gaaggagacg ttaattatga gtaaaattat cggtattgac ttaggtacga
    15961 ctaactctgc agtagcagta ttggaaggaa acgaagcaaa aatcatcgct aacccagaag
    16021 gaaaccgtac aacaccttct gttgtatcat tcaaaaatgg agaaatccaa gtaggggaag
    16081 ttgcaaaacg tcaagctgtg acaaacccaa atacgatttc atcaatcaaa cgccatatcg
    16141 gtgaagcagg ttacaaagta gatgtagaag gtaaatcata tacaccacaa gaaatctcag
    16201 caatgatcct tcaatatatc aaaggattcg cagaagacta tttaggtgaa aaagtcgaaa
    16261 aagcagttat cactgtgcca gcttacttta atgatgcaca acgtcaagca acaaaagatg
    16321 ctggtaagat cgctggtcta gaagtagaac gtatcgtcaa tgaaccaact gcagctgctc
    16381 ttgcctatgg tttagataaa acagatcgcg acgaaaaaat cttagtattc gaccttggtg
    16441 gcggtacttt tgacgtatct atccttgaac taggagacgg tgtctttgat gtattgtcaa
    16501 cagctggcga caaccatcta ggtggggacg actttgataa caaaatcatc gactacatgg
    16561 tagcagaatt caaaaaagaa aacagcattg acttgtctca agacaaaatg gctttacaac
    16621 gcttgaaaga cgctgctgaa aaagcgaaaa aagatttatc tggcgtatca agcacacaaa
    16681 tcagcttgcc atttatcaca gcaggagaat ctggaccatt gcatttggaa atgacattga
    16741 cacgtgcaaa atttgatgaa ttaacagctg acttagtaga acgtacaaaa gtaccagtac
    16801 gtcaagcgct aaaagatgca ggtttatcac aatcagaaat cgacgaagtt attttagtcg
    16861 gtggatctac tcgtatccct gcagttgtag aagcagtacg taaagaaaca ggaaaagaac
    16921 caaacaaatc agttaaccct gatgaagtag ttgctatggg tgctgctatc caaggtggcg
    16981 tgatcactgg tgatgtgaaa gatgttgttt tacttgacgt tacaccattg tcattaggta
    17041 tcgaaacaat gggtggagtg ttcactaaat tgattgaccg caatacaacg attccaacaa
    17101 gtaaatcaca agtattctca actgcggcag ataatcaacc agcagtagac atccatgtat
    17161 tacaaggtga acgcccaatg gctgctgaca acaaaactct aggaagattc caattgacag
    17221 atattccagc agctcctcgt ggtattccac aaatcgaagt aacattcgat attgataaaa
    17281 acgggattgt aaatgtatct gcgaaagatc taggtacaca aaaagaacaa aaaatcacga
    17341 tcaaatcttc ttcaggtcta acagacgaag aaatcgaacg tatggtaaaa gatgcagaag
    17401 caaatgcaga agcagataaa gctcgtaaag aggaagttga cctacgtaat gatgtagatg
    17461 cattgctatt ctctgtggac aaaacattga aagaattaga aggcaaagtg gacgaagaag
    17521 aagtgaaaaa agcagaaaca gctcgcgatg aattgaaagc cgctgttgaa gcaaacaaca
    17581 tcgaagaaat gaaaactaaa cgcgatgcat tgaacgaaat cgttcaaaac ttgactgtta
    17641 aactatacga acaagcggca caacaacaag ctcaagaaaa cccagaagca gctcaaggcg
    17701 gagcagatga tgtcgttgat gctgattttg aagaagtcga tggcgacgat aaataatcag
    17761 ttcactgaat ttcgagagaa ggccaaagtt gctactttgg ctttttcttt tgaaaaatag
    17821 tttgaagtat cggtttttgt ttcaaacaaa atatgatatg ataacaagcg acgtgaaaat
    17881 gatgagaacc aataggagga aagcctatgg caacaaaacg tgattattat gaagtcttag
    17941 ggctctcaaa aggagcatca gaagatgaaa taaagaaagc ttatcgtaag ctttcgaaaa
    18001 aataccatcc tgacatcaat aaagaacctg atgcggaaga aaaattcaaa gaagtatcag
    18061 aagcatatga gattttaagt gacccgcaaa aacgcgctgc atatgaccaa tacgggcatg
    18121 caggcacaga tccaaattac ggtgctggtg gagctggtgg cggatttggt ggattcggcg
    18181 gcttctctgg tggcggcttc ggtggttttg aagatatctt cgactctttc tttggaggag
    18241 gcggtcggtc agtcgatcca aatgcgcctc gtcaaggtgc tgatttgcaa tatacggtcg
    18301 acttgtcttt tgaagaagcg atttttggtg tagaaaaaga aatcaagtat aatcgggaag
    18361 aaatctgtca tacttgtggt gggaacggtg caaaaccagg cacacaacca actacttgtc
    18421 ataaatgtca tggtgcaggt acgattaatg tagaacgcca aacaccactt ggacgagtga
    18481 tgagccgtca aacttgtgat gtttgtcatg ggacagggaa agaaatcaaa gaaccttgtc
    18541 caacctgtca tggctcagga catgagaaga aagcacattc agttaaagtg aatgtaccag
    18601 ctggtgtaga agaaggacaa caaatgcgtt tagctggtca aggagaagct ggagaaaacg
    18661 gcggaccatt tggtgatttg tatgtggtct tccgtgtaga agaaagtgat atctttgatc
    18721 gtgaaggttc tgaaatttac tatgaattgc ctttaagttt tgtacaagca gctttggggg
    18781 atgaagtcca agtaccaact gtccatggag atgtgaaatt gaagatccct gctggaacac
    18841 agacaggtac gaacttccgt ttacgtggaa aaggcgctcc gaagttacgt ggtggtgcaa
    18901 caggcgacca acatgtcaaa gtaaaactga tcacaccgaa aaatctaaat gaacaacaaa
    18961 gagaagcatt acgtgcattc gctgaagctg gcggcatcaa agttgaagaa cagcaagaag
    19021 acggtttctt cgataagttt aaagatgctt ttggcgggaa aaagcggaag tagtttttct
    19081 agtaaaaacg ctaagtcatt aataattaaa aaccagacga acaatcatat gttcgcctgg
    19141 tttttttgta gttgtcatgt ttgtaccaac aaaaaagcca gctttagaat atgataatcg
    19201 tcatagtttc taggggtata accagtgaga gaatggaact tgttcaatcg atattgcaag
    19261 gtgtttttat gaataaataa ttcttctgag caatttttga tgcttccgtt atttttactg
    19321 aagcatgcca aagtcttctt gaacaaatgt acttcttctt ctgtcaggct tttcaaaata
    19381 cgttttacat ataatgttcg ttgatctgac gggattgctg gtaaaacgat cccgaggtct
    19441 aaatcttcaa aaaagcggat ctcgttcaca gattgatgga aagctatcca ttcgcaaact
    19501 tgtttggcat gaaggaaaga ttgcggtgtc tcttgctctg tataacaaag cgacccaatt
    19561 ccaaagttta gctgtaactg atacatttta ttaaactttg tctggatttt atcaagcaat
    19621 gatagcaatg aggctctgga aatccgattg actaggataa tgatttgttg tctatgtaca
    19681 gtgagcaaag cctgtccgta ataagagaag accctttcga gcaactccaa taaaggattg
    19741 atccgttctt gacacaattg ctgattgtca gaaagttgtc ccacaactac ataatatgga
    19801 gaagaaaaat caagctcaat taagtgaggg tggtatcgac tatgtacttg atatcatcaa
    19861 tgaaccgatg gtactttctt atgcgatgga acaggtagag cgattgcttg tttgtgcagg
    19921 aaaacaagcg atgcggctga tacgattagg tgagaaaata agaagataaa aatacacggt
    19981 cccttcatgg cgaccgtgca tttttggttt ttattaaata tttaatactt tattcaagaa
    20041 atcttttgtc cgttcatttt gcggattttc aaagatttgt tgaggcgttc catcttctaa
    20101 aaagtttccg tcgtcaatga acatgacgcg attggccact tctttagcga accccatttc
    20161 gtgcgtaacg ataaccatcg tcataccttg ttctgctaac tttttcatga cgttcaagac
    20221 atcaccgacc atttcaggat cgagtgcaga agtaggctca tcaaaaagca tgatgtcagg
    20281 gttcatcgct agagcacgag caatagccac acgctgtttt tgtccaccag aaagcatttc
    20341 aggatacata tcttttttat cttctagacc aactgtctgc agtaatttga ttgctttttt
    20401 ctctgcttct tctctagatt ctttcttcag gtccatcggt gctaaaatga tgttttccaa
    20461 aatagaaaga tgagggaata ggttaaagtg ttggaatacc attccgatat gttgtctcac
    20521 caagttgata tctgtgcttt tatccatcaa gtgggcgccg tcaataataa tttcaccgtc
    20581 agaaggttct tctaaacgat tcaagcaacg caagaatgta ctttttcctg aacctgaagg
    20641 gccaatgata cagacgacat ctccttcgtt gatggataca ttgatgtcgt ttaatactgt
    20701 gttatcgccg tattttttga ctaaatgctc aactaagatt ttttctgcca tcttacttca
    20761 ccttcttttc taaaactttt gctaattttg tcaatgctgt gatcaaaatc aagtacatga
    20821 tcgcaatgat caagtaaaca tacgtacttt gtgttgtacg tgcaacaatg atcttaccag
    20881 tttgcagcaa ttcgactaca ccgattgcgg aaatgatcgt tgtgtctttt aatgagataa
    20941 cgaactgatt gacgaatgat gggatcatga tgcgtatcgc ttgcggcaaa atgatttttt
    21001 gcattgtccg attataagaa agacctaaac ttctggaagc ttccatttgt ccgacaggaa
    21061 cggcgttgat cccgcctcga acaatctctg cgatataagc acttgcgtta agagtcaagg
    21121 tgataacacc agcaaggaag tcaggaatcg taaatccaac gataccaggc aacccaaaga
    21181 aaataaagaa cgcaagaacc atcattggaa ttcctcggat gatatcgaca taaatactag
    21241 caattgtgcg aagagcgcgt attggtgcta cactgaataa tccaaaaatc acaccgatta
    21301 ctatagccaa agcaaaggag atcaaagtta ggagaattgt tctccaaagt cctttcaaca
    21361 atgcttgata gttgttttgg ataagtccaa gaaatgttga ttcatcagca gtggaagact
    21421 cactggaagt ttctgaacca tccgctacat attctttaat aatcttatcg tattcgcctg
    21481 ttctttttaa ttctttcaat ccttcattga acatattaag aagctcagga ttttgtcctt
    21541 ttttaacggc aaatgcatat tttccgccag attctttttt gatcggtgtt tccaattctt
    21601 gtccttgttt gatcgcataa ccgattaccg gataatcatc catcattgca tcgattgcgc
    21661 caacttttaa cccgtcgtac aattgatcag cagcatcaaa atatttgata gaatagccat
    21721 attcagattc atggtcgctt aaaaattcag cactttcggt accaactttt gctccgactg
    21781 tttttccttt caaatcttca taagacttga tcgaagtatc tccttttttg acagctaatt
    21841 ggatcccgct atcaaagtaa gaatcagaaa aatcatagct tttctttcgt tcatctgtta
    21901 cagtcattcc ggcaatcatt ccgtctgctt gtcctgattc caaagcttgc aaagcagcag
    21961 agaaaccacg gtagtccatt cggatgttaa atccttgcag tttggcgatg ttttccatca
    22021 attttacatc gatgccttcg tactcgccct ttgcgttttg aaattcaaat ggagcaaaag
    22081 cagagtcact ggcaattacg tatacgtctt ttttgggctc tattttttgc attgtctcgc
    22141 ttgtgcttga ctctgccgtt gtagtgttgt cagcttgtgc aacatgacca aacgcaagtg
    22201 tcacaagtcc tgtcattaag aaaacaaatg agtgaaataa atgctttctt ttcataatca
    22261 acctcctaaa tttccaatat tttattatta taggcgaaaa gtgctgaatc agacaagact
    22321 gtaagctcga aaaaatgaaa aaaatgcgag tttctaacat tttatgttat aaaacataac
    22381 atgtataata agataaaaaa gtggcgaaag tatgttcggt gtggtataat tttttagtaa
    22441 ggaatgcctt tgctttcctt ttctttttat tggtcgtaaa atgaaaagga atgaatgaaa
    22501 aggaggacga agaatgattg agagagatac ctcccgacac tttgagcttg tctcgaaata
    22561 ccaaccggct ggtgatcagc ctgaagcgat taaccaatta gtggatggcg tagtcggcgg
    22621 gaaaaaagca caaatcttat taggtgcgac tggaacaggg aaaacatata cgatttccaa
    22681 tcttattgag aaagtgaata aaccaacact gattattgcc cataacaaaa cattggctgg
    22741 tcagctgtac ggggaattca aggaattttt ccctaacaat gctgttgaat attttgtttc
    22801 ttattatgat tattatcagc ctgaagctta tgtgccttca agcgatacgt atatcgaaaa
    22861 agattcaagt gtaaatgatg agatcgacaa attacgacat tcggctacta gttcattatt
    22921 agaaagaaat gatgtgatcg tcattgcatc cgtttcatgt atttttggat taggctcgcc
    22981 ttttgagtac caaaaacaag tagtttcgat tcgacaggga gcagaactag atcgcaatca
    23041 gttgattcgt gacttagtca gtatccaatt cgaaagaaat gatatagatt ttcagcgcgg
    23101 tcgttttcga gtgcgcggtg atgtcgtgga gatttttccg gcttcaagag atgaacgtgc
    23161 cttacgtgtg gagttttttg gagatgaggt cgaacgtatc cgagaagtca atgcactgac
    23221 aggtgaagtt ttaggagaaa cggaacacgt agcaatcttc ccggcgactc actttgtgac
    23281 gaatgatgaa catatggagc atgccgtagc gaatatcaaa gaggaattag aacagcgttt
    23341 aactgtcttg cgaaatgaaa acaaacttct ggaagctcaa cgtttagaac agcgaaccaa
    23401 ttacgatatt gaaatgatgt tagaaatggg ctacacgtcg ggaattgaaa attattctcg
    23461 gcatatggac ggacgtaaag aaggtgaacc gccttatacg ctattggatt tctttcctga
    23521 agattttttg atcgtggcgg acgaatcgca cgtaaccatg cctcaaatca gaggaatgta
    23581 taatggtgac cgagcgagaa aacagatgct agtagattac ggtttccgtt tgccatctgc
    23641 tttagacaat cggccacttc ggttagaaga gtttgaaaaa catgtcaatc agatcattta
    23701 tgtctctgcg acgccaggac catatgaaca tgaacaaaca gataccgtta tccaacaaat
    23761 catccgtccg acagggctgc ttgacccagt gatcgaagtt cgtccaatca tgggacaaat
    23821 cgatgatcta gtaggcgaaa taaatgaacg agtcgaaaaa gaccagcggg tgtttgtaac
    23881 gacattgacg aaaaaaatgg cagaagacct cacagattat ttcaaagaat tagggatcaa
    23941 agtcaaatat ttgcatagtg atatcaaaac gctggaacga acagaaatca ttcgagatct
    24001 tcgattaggt gaatttgatg tgttagttgg aatcaatttg cttcgtgaag gattagacgt
    24061 acctgaagtt tcccttgttg ctatcttgga tgcggataaa gaaggctttt tacgtagtga
    24121 acgttcctta gtccaaacga ttggacgagc tgctcggaat gaagaaggta aagtaatcat
    24181 gtacgcagac aaagtaacag attctatgcg tctagcgatg gatgaaacgt caagacgtcg
    24241 tacgattcag cagaagtaca atgaagaaca tgggatcgtt ccaaaaacga tcattaaaga
    24301 aatccgagat ttgatttcta ttacgaaaga atcggaagat gatacaaaag aagcggtaca
    24361 agtctcgtac gaagaaatga cgaaggaaga aaaagacacg ttattgatga aattagaaaa
    24421 agaaatgaaa gatgcggcaa aagctttgga ttttgaaaca gccgcgaatg tgcgagatat
    24481 gattttagaa ttaaaagctt caaagtagga ggacaacatg gctaacgata aaattacgat
    24541 tcatggtgca cgtgcccata acttgaaaaa tatagatgta acgattccac gagataaatt
    24601 cgtggtcgtt acaggtttgt ccggttctgg aaaaagttcc ctagcatttg atacgctgta
    24661 cgctgaaggg cagcggagat acgtagagag cctttctgct tatgctcgtc agtttttagg
    24721 acaaatggat aagccggacg tagatagcat cgacggattg agtccggcga tttctattga
    24781 tcagaaaaca acaagtaaaa atcctcggtc gacagtaggt actgtgacgg aaatcaatga
    24841 ctatttacgc ttgttgtttg cacgtgtagg acatccgatt tgtcccaacg atcatatcga
    24901 gattaccagt caatcagtag atcaaatggc agatcaagta atggctttgc ctgagcgcac
    24961 aaagatccaa gtgttggcac cgatcgtggt aaagaaaaaa ggacaacata aaaaaatatt
    25021 cgaacgaatc caaaaagagg gatacgtccg cgttcgagtc gatggtgaga tctatgattt
    25081 aagtgaagtg cctgagctgg agaaaaacaa aaaacatgat atcgcgatcg tcatcgaccg
    25141 gatcattgtg aaagaaggga ttcgttctcg cctatttgat tctttagagg cggccctgcg
    25201 attagcagac ggctatgctc tggttgacgt gatcggtgaa gaagaaatgt tgtttagcga
    25261 acactatgcc tgtccttatt gcggatttac tgttggcgaa ctagaaccaa gactgttctc
    25321 attcaatgcg ccttttggag cttgtccaga ctgtgatggt ttaggtgtca aattagaagt
    25381 cgatcaagat ttagtgattc cagatagaac gaagacactt agtcaaggtg ctatcgttcc
    25441 atggaatcca atcagctctc agtattatcc tcaaatgtta gcgcaggctt gtgaaagttt
    25501 cggtatcgat ttagatacac cattcgaaga attaccggaa gagcatcagg agatcatctt
    25561 gaatgggaca gatgatcttt tccatttcca ttatgaaaat gattttggtg gcgttcgcga
    25621 tgtagaaacg actttcgaag gggtattgaa gaatatcgag cgtcgttatc atgatacgaa
    25681 cagtgatttc acgcgtgagc aaatgcgtct ttatatgaca gaattaactt gtcagacatg
    25741 taaaggttat cgattgaatc cccaagctct atctgttcaa atcaatggaa cgaatatcgg
    25801 gcaaacaaat gagttgtcta ttcaaaaagc agtagatttc ttctcaaact taacgttatc
    25861 tgaacaagag aaagtaattg ccaaaccgat tttaaaagaa gtaaatgaca gactttcatt
    25921 cttggaaaat gtgggactag actatctaac tttgagtcgc gcttccggaa cattatctgg
    25981 gggagaagcg cagcgaatca gattggctac acaaattgga tcgaatcttt ctggagtttt
    26041 gtatatttta gatgaaccat cgatcggatt gcatcaacgc gacaacgatc gactgattgg
    26101 ctcattaaag aaaatgcgtg atcttggcaa caccctcgtt gtagtcgaac atgatgaaga
    26161 tacgatgtgg gcagcagatt atttgattga cgtcggacct ggggccggag aacaaggcgg
    26221 acaaatcgtg gctgcaggca ctcctgaaga agtagctaat gatgaaaatt ctttgacagg
    26281 gaaatatctt tcagggaaaa aatcaatccc tgtaccaaaa gaacgccgta aaggtaatgg
    26341 gaaagcaatc aagatcactg gtgcttcaga aaacaatctg aaaaatatta gtgttgaatt
    26401 tccattagga gaatttgtag cagtcacagg tgtgtctggt tctggaaaga gtacattggt
    26461 caatagtatc ttaaagaaat cgttagcgca aaaattaaat aagaattctg ctaagccagg
    26521 taaattcaag acaatttccg gctacgaaag tatcgaaaag atcatcgata tcgatcaaag
    26581 cccaatcggc cggacgccga gaagtaatcc agcgacttat acaagtgtat ttgatgatat
    26641 ccgtgggtta tttgctcaaa cgaacgaggc aaaaatgcgg ggttataaga aagggcgttt
    26701 tagtttcaac gtaaaaggcg gtcgttgtga agcttgtcgc ggggatggaa ttattaagat
    26761 cgaaatgcac tttttgcctg atgtctatgt tccttgtgaa gtatgtcatg gtaaacgata
    26821 taattctgaa acattagaag tgcattacaa aggaaaaagc attgctgata ttttggaaat
    26881 gacagtagag gatgctgtag aattcttcaa gcacattcca aagattcatc gcaaactgca
    26941 aacgattgtt gatgttggct taggttatgt gacgatgggg caaccagcaa cgacattgtc
    27001 cggtggtgag gcacaacgga tgaaacttgc cagtgaattg cacaaaatct ctaatggaaa
    27061 gaatttctat atactagatg aaccaacgac aggacttcat agcgatgaca tcgcccgctt
    27121 gttgcatgta ttacaaagat tagtagatgc tggtaacaca gttttagtga ttgaacacaa
    27181 tctagatgta atcaaaacag cagattatat cattgattta ggaccagaag gtggagaagg
    27241 tggaggaacg atccttgcga ctggaacacc agaagaaatc attaacgtaa aagaaagtta
    27301 tacaggtcac tatttgaaaa aaataatggt ataaagagga tagatagctg agatagttaa
    27361 aaaaacataa aaaaatgaat ttttgcttgt tttattaata tcagtgttct agaatcatta
    27421 catggtagtt ctttctacac tgattggtat agataaaaac ttcctataag ttcaatccgt
    27481 tcaaaaaaga attgagcaat cggaggactt tcctttgatt gcttttttct ttatggtatg
    27541 atattccttg tgtagttgga aaagaaaaac aagagattat gagtaagtga gagataatga
    27601 tgaacagtat tgaaaatgaa gaatttatcc ctatattatt aggaagcgac atgaacgttt
    27661 atggtatggc acgttctttt aatgaagcat acggcaaaat ctgccaagca tatgcttcgg
    27721 atcagttagc ccctacccgc tacagtaaaa ttgtcaatgt agaagttatt ccaggatttg
    27781 ataaagaccc tgtatttatc gagacgatgc ttcgtttggc aaaagaaaga tattctgata
    27841 agagtaaaaa atatcttttg attgcttgtg gtgatggata tgcagaattg atctcccaac
    27901 ataaacaaga gctgtcagaa tattttatct gtccatatat tgattattct ttatttgaaa
    27961 ggctgatcaa taaagtaagc ttttatgaag tttgtgaaga atatgatctt ccgtatccta
    28021 aaacattgat cgtcagagaa gaaatgttag taaatggaca tttggaacag gaattgcctt
    28081 ttgaattccc agttgctttg aaacctgcaa acagtgtgga gtatctttct gtccaatttg
    28141 aaggaagaaa aaaagctttt attttagaga ctagagaaga gttcgattta attttaggcc
    28201 ggatatacga agccggttat aaaagtgaaa tgattgtaca agattttatc ccgggtgatg
    28261 atagtaatat gcgtgtgcta aatgcgtatg tagatgaaga tcatcaagtt cggatgatgt
    28321 gccttggtca tccactatta gaagatccta caccagcatc gattggtaat tacgttgtga
    28381 tcatgccaga ttataacgaa aaaatctatc aaaccattaa ggcatttttg gaaaaaatcg
    28441 aatatacagg ctttgccaat ttcgatatga agtatgatcc tagagatgga gaatataaat
    28501 tatttgaaat caatttgaga caaggtcgta gcagtttctt tgtgacattg aacggcttga
    28561 atctggctcg ttttgtcaca gaagatcgag tgttcaacaa accctttgtt gaaacgacct
    28621 atggaacgaa tcaatcagat aaagcaagat tatggatggg tgtgcccaaa aaaatctttt
    28681 tagaatatgc tcgggaaaat gaagacaaaa aactagctga gcaaatgatc aaagaaaatc
    28741 gttacggtac tactgtattt tatgaaaaag accgatcaat caagcgctgg ttgttgatga
    28801 aatatatgtt ccataactat attccaagat tcaaaaagta ttttcatgtg aaagaaggct
    28861 agttcatgga gaattttttc agtattttag gcggaatggg cacgatggcg acagaaagtt
    28921 ttgttcgctt gatcaaccac cgaacgaaag ctacaaaaga tcaagaatat ttgaattatg
    28981 tcttattcaa tcatgcaaca gttcctgatc gtacagctta tattttagat cgatcagaag
    29041 aaaatccaat gccgtttctg ctggatgata ttgagaaaca aaatttattg cgaccaaact
    29101 tcattgtgtt gacttgtaac accgcacact acttttttga agagttacaa gcggcaacgg
    29161 atattcctat cttgcatatg ccaagagaag cagcaaatga acttgtccgt cagcatacga
    29221 cagggagagt agcgattcta ggaacagaag gaagtatgaa agctggaatc tatgaacgcg
    29281 aagtcaaaaa tcttggtttc gaaacagtga ttcctgatac tgcgcttcaa gaaaaaatca
    29341 attacctgat ctatcatgag atcaaggaat cggattattt gaatcaagag ctctattacg
    29401 aaatcttaga ggaagcggta gagcgcctaa actgtgaaaa agtcatccta ggttgcacag
    29461 aattatcttt gatgcatgaa tttgctgaag ataatcatta cccagtgatc gatgctcaat
    29521 ctattttagc ggatcgaacg atcgaacgtg cattagctga aagaagcgag gcattggata
    29581 cagcatcgga aaagtaaaaa aattggattt ggggcaaata tcctaaaaga tatttggtcc
    29641 aaatcttttt gtaaaagaaa aagaaaactg gtaatgatac gcccgggatg atataatttt
    29701 attatgcaca atgtgagagg ggttcgtaaa tatgacagat aatttgcaat tagtcatcat
    29761 aacaggtatg agtggtgcag ggaaaacagt agctatccaa agttttgaag atatgggcta
    29821 tttttgtatc gataatatgc cgcctcgatt gattccaaaa ttctgggaat tgatcaaaga
    29881 atcaggtaaa gtcacaaaaa tggctttagg agtggatttg cgttctcgtt ccttctttga
    29941 agaaatccaa aacatgctga tcgaaatcga aaatacgaac ttcatcgaca cttctatctt
    30001 atttttagat gcttcagacg aagaactagt ggctcgctac aaagaaacaa gacgagcaca
    30061 tccaatggcg atggacggtt tgatcactga agggatacgt aaagaacggg cgatactaga
    30121 cgacttgaaa gcccaagctt ccgtgatcat tgatacgaca acattgacac cacgacaatt
    30181 acgtgaaaaa atcaatgagt cattcaaatc aaagggagac caaggatttc ggatcgaatt
    30241 tgtatcattt ggttttaaat acgggttgcc gatcgattcg gatattgtga tggatgtgcg
    30301 ttttttgccc aaccctcatt atatcccgga actaagacca ttgaccggaa aagatcagcc
    30361 agtctatgat tatgtgatgt cctttgatga aacgcaatca ttctaccata aatttttgga
    30421 tcttctggaa actgtattgc ctggatacat taaagaagga aaaagcagct tgacagttgc
    30481 aatcggctgt acaggcggtc aacaccgttc tgtggcattg actgaacgtt tggcaaatgc
    30541 tttagggaaa aactataaag tcaatgtgac acatcgggac aaggataaaa ggaaagagac
    30601 ggtgaaccgg tcgtgaaaat gaaaacctac cggataagaa aaccaaagat cgtagtggtc
    30661 ggcggtggca ctggtctgcc agttatcctg aaaagtttac gaaatcaagg agcagatatc
    30721 acagcagtag tgactgttgc agatgatggt ggaagcagcg gtgcaatcag agaatcgatc
    30781 gctatggctc ctcctggtga cttgagaaat gtcttagtgg cgttatcgga tatgccacaa
    30841 ttctatgaag atattttcca ataccgtttc aaaaaggaag atcagttttt agccaatcat
    30901 acgatcggta atctgatcat tgccgcagtt tccgagatgc ggggaagcac ttatgaggcg
    30961 attcaattat tagcaaaaat gatgcatgta gatggacatg tttatccttc ttcagaaact
    31021 cctttgacct tgcatgctgt ttttaaagac ggaacgactg cagtaggaga atctaaaatc
    31081 gcgatcaacc gtaaaaccat tgaccgtgtg tatgtctgca acacaaatga taaaagtgaa
    31141 gccaaagcgg ctcgaaaagt cgtttcagca attatggacg ccgacatggt cgttttggga
    31201 cccggaagtt tattcaccag tatccttcca aatttagtga taccagaaat cggcgaagca
    31261 atgctcaaga caactgctga aaccgtctat atctgtaata tcatgaccca aaaaggggaa
    31321 acggaacatt tcacagatgc cgatcatata cgtgttttac acaagcattt gaatcagcct
    31381 tttatcgata cagtattggt caatacggaa aaagtgcctg aagattatat ggacccagag
    31441 atctatgatg agtatctagt acaagtcgca cacgacttca acggattgag aaatgaagga
    31501 tgtcgagtga tttccaccga ctttttagaa ttgaaagatg gtggtgtctt ccacgatgga
    31561 gacaaagtag tagaagaatt gttccgttta gttttcggtt caaaatatta agcaatttat
    31621 tgttggagaa aggaggagaa taggatgtca tttgctgcag atgtgaagaa agaactaact
    31681 ggtttggaag ttcatcgaga acatgcgaaa gcggaattag ctgctttgct gcgaatgaac
    31741 ggctctttag gtattgtgaa ccagcagttt attttgaacg tccaaacaga aaatgctgca
    31801 attgccagac gtatctattc tcttttgaaa gatcattatc aggtacgaag tgagctactc
    31861 gttcgtaaaa aaatgaaatt aaaaaagaac aatgtctata tcgtccggtt gaagcaaggc
    31921 acaaaagatg tgttgatgga tcttgatatc atggatggta tgatgttcaa tggacacgtt
    31981 tcggacgaga ttatgggaaa ttcgcaaaaa atgcgttctt acttacgtgg tgcttttatg
    32041 gcctcaggtt cagtcaataa tccggaaacg agtcgttatc atttggaaat attttctatt
    32101 tatgaacagc ataaccaaga catttgcgat atgttaaatt attacggtct acatgctcga
    32161 acgcttgaac ggcgcaatgg ctatatttcg tatttaaaag gagcagaaaa aattgctgat
    32221 ttcttaacat tgattggtgc aaccaactca atgctccgat ttgaagatgt tcgaatcgta
    32281 cgggatatga gaaattcggt caatcgtcta gtcaattgtg agacagcaaa tctgaacaag
    32341 acgattgatg cggcttctaa acaaatcgaa aacatcgaat tgatcgaagc aaaggtcggt
    32401 ctacatgccc ttcctgaaaa acttcaggaa atcgcagaac ttcggcttca acatccagag
    32461 gtcagcttga aagaattagg ggaaatgatt ccctcaggtg caatatcaaa atcgggaatt
    32521 aatcaccgaa ttcgcaaaat aaatgaattt gcggaaaaac tgcgtgaaga agcagtttaa
    32581 tccaaagaaa aaactgatac atgaagcagg agatgcgaat gtatcagttt tttttaaaag
    32641 ctatacttgc ttttcttccg tcaaactata attccaactt tactggagta acataatgtt
    32701 gaaaggcttc tattgttttt taatacaatc gtataaaaag cggggagaca actgaatgaa
    32761 gattttagtt ttatacataa acttttgctt aatatagaag tcctgatata gataggatca
    32821 agtatttatc tataactgga gattaattaa aaactggaag gaactgctcg atcaaccttg
    32881 agaactgttt ttcttacttc tggtcaagat tctcgtggtt ggtggataag gatggttgat
    32941 aagttcattg gattagctag tcgaaaacaa ccaggtgtaa ttaatgtaga agttttaaca
    33001 aggggatgga gtgatttatt cagtgataat cataagttca taaatagtaa ttgggatgta
    33061 tggttggtat acgttatacc tgaacttgaa ctatcaagat ttggtttaga atttgagaat
    33121 cgatgtttat aaagggaggg caaaaaatgt gcttttttac aacttttact atcattatga
    33181 ttgcagtact ttttattttt ctagatatag caaagcgaaa tacagcattt ttattatatc
    33241 gggttttact tcgagcaggt ctcataacat ttatatcgat cgttggattt tttctattca
    33301 cagttattgt atttatttgg agaactacag caccaccatt gccagagatt acatatggag
    33361 aatttccgtt tagtcttgaa tatgaaatag atgaggaaag aattttgatt gaagatacgg
    33421 tgattgcaga atttatagga agttttagag ggaatgtgac aactcaacct agacgaagtt
    33481 ggagtataaa acttttaaat aatagtggag agttgaaagc atttcattat gaattcttaa
    33541 taatagaaag tgaagatgta acaatcactt taagtagtgg ctctgctgga tattttatga
    33601 atgatggtgg aagcaagcca cagctcacag tccgtgatcg tattgcaggt tttatgcatt
    33661 tttctcacta tgacttagaa gaagctcgta aaatacttgc agaatatggg atcacattaa
    33721 tcaattggga atatgcgcca ccgataagaa attttttcaa tgattattat tagtcttata
    33781 aaaaacagaa tgtaaaattt atgtgcgcga gtatttagtt ttccattttt tgtttgatag
    33841 atatatagca ttgttgaagc atgggatagt ggtgccaatt ttatcaatga ggttggtcag
    33901 gcagttaaca taattggtga tgctataaat ccatttaatt ggaattggag gaattaggtg
    33961 tggaaacagt gagattatgg atattcatga aaaattttcg ttcggctttg agatatgtta
    34021 ttctggaatc aaaatcaggt tattatctga ttgacacaga tcactatact ttttggggag
    34081 gctacctttt tccgattttt aattggataa tcccccataa ggttatgaaa attaacttgc
    34141 ctgcagaaga aataaataga ttaatactca acaaagattt acaaaggaaa agagagaaag
    34201 aacattctaa tgttgcttgg ataggtccag catttgcagt agtgacttct tcaattgtcg
    34261 gtcctatgct agagagtatt tatagtgatt tttctattgg aatacgttat ttatttgtta
    34321 ctttaagtat agctgttctt ttgtgcataa agggttatgt tagcaagaag aataaagata
    34381 ttttaacact aatcggtgta aacaatttat ctagtactaa aattatactg tttcctgaat
    34441 ctataaaaga aggatcaagg ttgttgataa tttttataat gcttatactg ttttctgttt
    34501 tatttggggt gatgtttata ga
//
LOCUS       DARPZJ010000026        30718 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.027, whole genome shotgun sequence.
ACCESSION   DARPZJ010000026 DARPZJ010000000
VERSION     DARPZJ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.027"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            311..1090
                     /locus_tag="SLE23_001508"
     CDS             311..1090
                     /locus_tag="SLE23_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468419.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1136..2080
                     /locus_tag="SLE23_001509"
     CDS             1136..2080
                     /locus_tag="SLE23_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8468420.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="SLE23_001510"
     CDS             2096..2875
                     /locus_tag="SLE23_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HEI8468421.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="SLE23_001511"
     CDS             2887..3585
                     /locus_tag="SLE23_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HEI8468422.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="SLE23_001512"
     CDS             3613..4377
                     /locus_tag="SLE23_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEI8468423.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4422..5111
                     /locus_tag="SLE23_001513"
     CDS             4422..5111
                     /locus_tag="SLE23_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEI8468424.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6338..7018
                     /locus_tag="SLE23_001514"
     CDS             6338..7018
                     /locus_tag="SLE23_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEI8468425.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            7047..8360
                     /locus_tag="SLE23_001515"
     CDS             7047..8360
                     /locus_tag="SLE23_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEI8468426.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9166..9933
                     /locus_tag="SLE23_001516"
     CDS             9166..9933
                     /locus_tag="SLE23_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEI8468427.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9960..10961
                     /locus_tag="SLE23_001517"
     CDS             9960..10961
                     /locus_tag="SLE23_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEI8468428.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10984..12270
                     /locus_tag="SLE23_001518"
     CDS             10984..12270
                     /locus_tag="SLE23_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HEI8468429.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12304..12957
                     /locus_tag="SLE23_001519"
     CDS             12304..12957
                     /locus_tag="SLE23_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8468430.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12990..14195
                     /locus_tag="SLE23_001520"
     CDS             12990..14195
                     /locus_tag="SLE23_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8468431.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14325..15650
                     /locus_tag="SLE23_001521"
     CDS             14325..15650
                     /locus_tag="SLE23_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468432.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            15667..16797
                     /locus_tag="SLE23_001522"
     CDS             15667..16797
                     /locus_tag="SLE23_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468433.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16823..17908
                     /locus_tag="SLE23_001523"
     CDS             16823..17908
                     /locus_tag="SLE23_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HEI8468434.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     GTLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17931..18746
                     /locus_tag="SLE23_001524"
     CDS             17931..18746
                     /locus_tag="SLE23_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468435.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18730..20448
                     /locus_tag="SLE23_001525"
     CDS             18730..20448
                     /locus_tag="SLE23_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HEI8468436.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDSKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20474..21310
                     /locus_tag="SLE23_001526"
     CDS             20474..21310
                     /locus_tag="SLE23_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8468437.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            21315..22748
                     /locus_tag="SLE23_001527"
     CDS             21315..22748
                     /locus_tag="SLE23_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEI8468438.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            22786..24426
                     /locus_tag="SLE23_001528"
     CDS             22786..24426
                     /locus_tag="SLE23_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HEI8468439.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            24514..24912
                     /locus_tag="SLE23_001529"
     CDS             24514..24912
                     /locus_tag="SLE23_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HEI8468440.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            24937..25653
                     /locus_tag="SLE23_001530"
     CDS             24937..25653
                     /locus_tag="SLE23_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8468441.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            26885..27464
                     /locus_tag="SLE23_001531"
                     /pseudo
     CDS             26885..27464
                     /locus_tag="SLE23_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            27524..29176
                     /locus_tag="SLE23_001532"
     CDS             27524..29176
                     /locus_tag="SLE23_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEI8468442.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            29520..29885
                     /locus_tag="SLE23_001533"
     CDS             29520..29885
                     /locus_tag="SLE23_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEI8468443.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            29973..30416
                     /locus_tag="SLE23_001534"
     CDS             29973..30416
                     /locus_tag="SLE23_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468444.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(30571..>30718)
                     /locus_tag="SLE23_001535"
     CDS             complement(30571..>30718)
                     /locus_tag="SLE23_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8468445.1"
                     /translation="EKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRY
                     SLGY"
BASE COUNT        10005 a         4479 c         6588 g         9646 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attttatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttaaggaaat aaaaatgaaa tcgattaatt gttatcttat taatgtttta
      121 tttactttta aatcataaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt ttttaaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggttacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctatgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttgtttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatattt aggattcgct gatactcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttgaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggcgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctcag caaatgggct atagcaatat
     1081 aagttattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc atagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaacttgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttacaatcg gtaaaatcac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagatc caaatggtga ctatggtaga caagagcgtc aaagaaagat
     1801 cgtagaaggt gtagcaaaaa aagtattgag tttaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaaaat
     1921 cgctttagat tatcgggagg catttggtac gatcaagcaa gatcagctgc aaggagaagg
     1981 ctttatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtaaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc aacttggaag aaatttttga aacattacgc aaacacttgg taacaatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca cagcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tggacaaatc aaagatgcga tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
     2461 ccaggcaata agcacgaatg cagtgactgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag acgtgatgaa tgtcgataaa atctcgatta tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
     2641 attaggaatg atggtaggcg taggtctggc attcttattc gaattacttg atcggacagt
     2701 gaaagatgaa aaatatgtga cggatgcatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga acgctggtat ccgtaaaaaa ggaacagctc ctgcacgacc
     2821 aaaagctaca aacgataaaa cagccccatc acgcagaagc cgctcaagag tctaggagga
     2881 agaaaaatgg cacgaacaca gaaacaaaaa gcagcacaaa ctcatgcagt cagtttgatc
     2941 acattaacaa acccatcttc accaatcgcc gaacaatatc gtacgatccg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg tcgtgacttc atcaggtcct
     3061 ggagaaggaa aatccaccac tgcagcaaac attgcagtcg tttttgctaa atccggtcaa
     3121 cgagttctac tagtcgatgc agatttacgt aaacccgtcg tctataagac attccagctg
     3181 aacaatgcca ggggattaag tacagcactt agttcatcag gaagtgtagc agatgtaatc
     3241 caacgaacgc cagtcgagaa cttgtcgatt ttgcctagtg gacctaagcc acccaaccca
     3301 tcagaattgt taagttcgcc aagaatggat cagatcctag acgaagcaag acagttattt
     3361 gacgtggtga tattcgatat gccaccagta gtagccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacttt attggtcgta cgtgaaaata catcacgtaa agaatcattg
     3481 aataaagcaa aagaactgct agagatggta caagcacgag ttttaggtgt tgtatacaac
     3541 ggagcagaac atagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg catcacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aatggctttt ttttgagttg ttagaactag gaaagacacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaaat tactgcgcca agttatgttg gtgtatttgg caaagacatt
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgcc
     4201 catggggtct ctaagcgtac cttttactta aaagagtgct atgagcagat tgctaaggac
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gaaatcagtt atccagtcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagggaaag tatggaaagt gaagatttat
     4441 tatctcgtat tagtgaagta catcctaatc aagtttggtt ggataaagaa aaagttgaaa
     4501 aacgatatat ctatttattt tttaaaagaa tgattgatat tgtaggaagc attattggtt
     4561 tgattttagc ttctcctttg atgttctatg tagcttatcg aatcagaaaa gaagagccag
     4621 gaagtccgat atttttttgc catacacgtg ttggtaaaaa tggaaaaaca ttcaaaatgt
     4681 ataaattccg ttcgatgtgt ttagatgctg aagaaaaatt ggaagaatta cttgatcaaa
     4741 atgaaataga aggtgcaatg ttcaagatga aagaagatcc ccgtgtcact aaaataggta
     4801 aaattatccg tgccaaaagc attgatgaat tgccacagct atggaatgtt ttaaaaggcg
     4861 atatgagtct aattggtcca cggccacctt tggagaggga agtagctgag tacacgagat
     4921 atgatcttca acgcttgtat gtaaaacctg gttgttcagg tttgtggcaa gttagtgata
     4981 gaaataatgt tagtttccat aaaatggttg agttggattt agagtatatt agtcatcgaa
     5041 gtttaatgta cgacttgagg ttgattttaa aaacgtttta tgttattgtc aagcccaatg
     5101 gagcatatta gttagggata gaatgatgga ttgttaataa aaaagattac acatgttcat
     5161 attatcgttt caaaagtaat aactgtaatt atggagggtt tgaatcactt gtagaaaatc
     5221 taaaaaaaga aaggtgaatg gggcaattca gtatcattat tcttatataa aagaaaatat
     5281 tcgaaatttt gggatgatac cactcttaaa tataatgatc taaatgcttt aatattggta
     5341 tatccgatat aggaactgac gagctattta gtatgataca aaagtatatt gatagccatt
     5401 aataaatttt ccaaaaaata atgacagcac accaattttt ataatttagc ttgttgaatc
     5461 ggtatgttca tgggacggtt caaaaaaaga atcgaaaaaa taaacggtaa aattttagtg
     5521 aatcctatgt aataaaattt ggatagatgg aaaaacagca cataaggagg ctgagtttgt
     5581 tgtcatttct gctcctacaa actatggtag tgaatgtgtt attgaattag tgatgtctgt
     5641 tacttcagag acattgggga taattaactt cactatacct gtagggtata caaaaaatgg
     5701 aagaaaaaat attatcaata gattttattt agttcagaat ttttacgtgg aagtaaatta
     5761 ttgatgataa tctttatcca attagaatta ttatcgtagg atgtgatgat gatagccgtg
     5821 aagttgttca agtatttacc aatgtctaca acgcagaaaa ttagtttggg tttttcggat
     5881 tggaaaattt caatgtataa aatcataaat ttgctgtaaa tagacagttt ggggtagtaa
     5941 tagcccaata aattgttcga taaactcatc tttggggtga gaatagctca atcattgaat
     6001 ttcaaacctg cctttggggt gggattagag gtcaatatgt acctacataa tactttttgg
     6061 aaaatgatgg tgttgagaat gtaagtacat ttcaatgtga aattctaata tagccccaaa
     6121 cgaggtcaat aaaaatgacc taaactcgta tttctcccct aaacgaggag gagatagata
     6181 tgaaaattga atgtgccggc gttggagttg gctgctttta gtaggaatga acatggttcg
     6241 atgagaactg tttcagatag agtggtcgat gatcacaggc ctttaagtcg tttacagatg
     6301 atgagacttg taaaaataga gggacgaatg gaaaaagatg attggtatag aagaaaagaa
     6361 aggtgttcag aaagacgtaa caattgatag ggaagagaat cttaggggac atagattcta
     6421 ttggattgga cgcagagcac aagatatctt cttctcggct ctagctttga ttgcattgag
     6481 ccctgtgatg ctaattacag cgctcgccat tgtgattgac gatcccggtg gcagcccgat
     6541 ttttgtgcag gatagagttg gaagaaatgg aaagctgttc aagttttata aattccgatc
     6601 tatgtgtgta gatgctgaag caaaattaga agccttgttg gcacaaaacg agatggatgg
     6661 tccggtcttc aagattaaag atgacccaag aatcacgaga gttggtaaat ttattcgaaa
     6721 gacaagtatc gatgagttac ctcagctctg gaacattctt aaaggtgata tgagtattat
     6781 tggacccaga cctgctttac cgagagaggt ggaacaatac ggtgactacg aaaggcagcg
     6841 gttgttcgta cagcctggtc ttagttgcta ttggcagatt gctccacatc gtaatgaact
     6901 gtcctttgaa gaatgggtgg aacttgatgt gaagtacatc aatgaaagaa gctttatcac
     6961 ggactggaag attatcttct tgactttaca ggctgtatta tttggatatg gtgaatgatt
     7021 atatatagta ttaggagttg aaatatgtga atattatttt attatcgggt ggtagcggta
     7081 ggcggttatg gccgctgtcc aacgatattc gtagcaaaca attcatcaaa ctgtttaagg
     7141 atgaaaatgg cgaatatgaa tctatgattc aaagagttta tcgccagatt acaactgttg
     7201 acccagatgc aaaggtcact attgcaacaa gtaagtctca ggctagtgca atccataatc
     7261 agttgggaga taaggcttcg atttgtgtag aaccttgtcg tagagatact ttccctgcaa
     7321 ttttgttagc tgcagcatat cttcacgatg aacttggcgt aggtgatgat gaaagtgttg
     7381 cggtttgtcc tgttgatcct tatgtagata attcctatta cgaaggcgtt gaagcccttg
     7441 agaagttggt gcagcagaat acggctaatt tgactttgat gggtattgca cctacatatc
     7501 ctagtgaaaa gtacggttat atcatccctg aaagttctaa cgaagtaagt actgttaagg
     7561 agtttaagga aaaacctgac aaagcaacgg cagagaaata tttagctcag aatgctgttt
     7621 ggaatgccgg tgtatttgcg ttcaaacttg gttacctgtt ggaaaaagct cacgcaatgg
     7681 tggattttga agattatcgt gatttgtatt ccaagtatga gactttaacc aagatcagct
     7741 ttgactatgc tgtggtcgaa aaagaaacga gcattcaagt gatgcgttat aacggggatt
     7801 ggaaagatgt cggaacttgg aacatgatgg ctgaagttat ggctgataat attaagggga
     7861 aagctgtaat ggatgatacc tgtgttaata ctcagattgt gaatgagttg aatattccta
     7921 ttcttgctat gggctgcaaa gatatggtaa ttgcagcaag tggcgatgga attctgattt
     7981 ctgataaaga gcgcagtggc tatatgaagc cgtatgttga gaaaatcagt acggaagtaa
     8041 tgtttgcaga aaaatcctgg ggtacatata ccgttatgga cgttcaggaa ggctccatga
     8101 ctgttaaagt ttctatgcag gccggacaga agttgagcta ccactaccac aattctcgcg
     8161 atgaagtttg gactgttgta gcaggacagg gtaaagcgat tgtagatggt atgaagcaga
     8221 ttcttcgtgc gggtgatgtg gtgactattg ccgcaggatg taaacataca atcgaagccg
     8281 tgacaaatct ggatattatc gaagttcaga ttggtgaaac tattagcgtc gctgacaagt
     8341 ataagagttc tttgaactaa aagttcgcga ggtagttatt atggagatac taaaatttca
     8401 acccgtgggt aaagattatc tttggggtgg agaacggttt aagacggaat ttggaaaaaa
     8461 ttgacttaac accattaagc ttatacgtgg gaatgcttag ttcatctaga cgataactac
     8521 gtacggaaat atcaaatatg aaggacagaa tggtaaaacc gagttgtggt atgtattgga
     8581 agctacaccg gggggtgatt tatgcttttg agtacgatgt aacagaagaa atgttacgaa
     8641 atgctgtgat ggacagatca cttgggaaac atttatataa agaagaagta cacaagggag
     8701 atctttttta tgtcagttca tggtattggc gctggagtat tagtggctga aatacaggaa
     8761 agctcaaatg ttacctatcg agtttacgat tatgatcgag tagataagaa tgataataag
     8821 tgagaattgt actttgaaaa agcgattcag gtaatgaata tggaagccac tttgaaattg
     8881 gagaaaagaa ataagctcat tcatttttat cctggtggct ctcgtgaaat actgtgtaga
     8941 tgtaaatact gtgagcccga aagaatccaa gtaaagacgg ggttttcgtt ctcggtaaaa
     9001 gaggaatctt ttcaagttct tttatgtata tcgggggacg gacaagttga gtcggcaaat
     9061 ggtgttatga aactcattag atttgtaaaa aagatattgt atgtttttgc caacgaatat
     9121 tggaagatgt taagtgttga gcgatgcgga cttactgaaa attagatggg gatagaggga
     9181 ggatatctaa tgtcacgaat gagatttatg aacacagaaa ttgacaatct tacaatgggt
     9241 gaagtattgg tagaggttga aaaaatgatt caagatagga gatgcggata tgttgtaact
     9301 ccgaatgtgg atcacattgt tcagttggaa acaggaaaag agttgcaaga tgtttataaa
     9361 aacgcatctt taattttgac ggatggtaaa ccattgattt ggatttcaaa gttttataag
     9421 acaccaataa aagaaaaaat atcgggatcc gatatatttt ctttactgtg caagatggct
     9481 gcagaaaagg gatacacaat gtatttttta ggtgcggcag agggcgttgc ggctaaagcg
     9541 gcagataacc tgatgaaaag atttccggga ttaaatgttg taggaacata ctctcctcct
     9601 tatgggttcg aaaaagacga agatgaaatg tttaaaattg attcccaaat taaacgagca
     9661 aatccagata tgcttattgt gggtttgggt tgccctaaac aggaaaaatt tatgttttat
     9721 aactgtgata gattgggagt acctgtgtct tttggtctag gagctagttt ggactttgag
     9781 gcagggaatg ttaaaagagc accaaaatgg atgtcagatt atggatttga gtggctgttt
     9841 agaattactc aggaccctaa aagaatggca aaacgatatt tggttgatga tttaaaaatc
     9901 tttaaattag cactaaaata tcggaaaaaa taaactatat tcaatgagga caatgaagta
     9961 tgattattac aaaaacacct tttcgcatgt ctttttttgg cggcggaacg gatatggaag
    10021 attattttcg agaaaatggc ggtgcagtgc tttccactac ttttgataag tactgttatg
    10081 tgaatgtgcg tcatttgcct agattttttg attacagcac agagttatca tattctcgta
    10141 ctgagagagt aacaaatatt gaagatatcg agcatcctgc aattcgtaat gcgatgaaaa
    10201 tgctagatat gcatgaaatt cgccttacat atgaagcaga tcttcctgca cgttctggtc
    10261 tgggtacatc tagttctttt gccgtaggta tgttgaatgc tttctatgct ttgaagggca
    10321 agtacgctga caagaagaaa ctcgttgata aagcaattta tcttgaaaga gtcctttgta
    10381 atgaagcagg cggatggcaa gatcagattg cagcagctta tggtggcttt aaccgaatca
    10441 atttcaactc agatggctat gaagtattgc ctattattat tacgcctgag cgtaaaaagc
    10501 agcttaacaa caacttgatg atgttcttta ctggattcac cagattttcc tctgatgttc
    10561 agaaggcaaa taatgtcagc ggcacagagg acaaaagagt aagactgaaa aaaatgtatg
    10621 agcttgtgga tgaagcagaa gcggttctga ctgataagaa cagagatcta gatgatttcg
    10681 gcagactgct tgatctcact tggagattga aaaaggctac cggtggtgcg attagcactg
    10741 gaagtatcga tgaactttat gaaaagggca tggctgctgg tgcattgggc ggtaaacttc
    10801 tcggagcagg tggcggcggt ttcttggttt tttatgttca gcctgaaaaa caaaatgctg
    10861 tgcgttcggc aatgagtaat ttgatgtata ttccgtttga atttgaaaac ggtggaacac
    10921 aggttattca ttacacaccg gaaatgtata ttccaaaata aagaaatcag cgaggataag
    10981 aatatgaaag ttgttattat ggcaggcggt aagggaactc gcatctcatc ggttgcaagc
    11041 gatattccaa agcccatgat taaaattgaa aacaaaccgg tattggagca cgaaatcgaa
    11101 tgtctgagag accagggatt cacagatatt attcttaccg ttagccatct tggcgatatc
    11161 attatgaact attttggcga tggttctgga atttcaccag ttactggtca gccctttgac
    11221 gttaaaattg aatacttttt ggagaaagag ccattaggaa atgccggtgc attgtttcgt
    11281 ttaaaggata atttgaccga agacttcctc ctgctgaatg cagatgcgat gtttgacgtt
    11341 gatttcaacc gatttgtagc atatcaccgt gaaaagggtg gcttggtgac attgtttact
    11401 caccctaaca gtcatccata tgacagcggt ctaatcattg cagataagga tggctctgta
    11461 gacagatggc ttgtaaagga agattcccgt ccaacttatt accgtaacag agtaaatgcg
    11521 ggactccatg tgattagtcc tgctgttctt gatgtcgaga taaacacacc taagattgac
    11581 ttggaccgtc agttattaaa gccgttggca ggaaccggaa aaatgttctg ctatgatagt
    11641 ccagaatacg taaaagacat gggtacccct gatcgttatt atgctgtctg tgaagatttt
    11701 aaggctggaa gagtgaaggg caaaaatctt cagaataagc agaaagctgt tttccttgat
    11761 cgtgatggaa cgattaatca atatgttggc tttctgcgtc atattgatga gttcgaacta
    11821 atcaagggta ctgaagatgc agtgaaaaag atcaatgccg ctggatatct ggctattgta
    11881 ataacgaatc agccagtaat tgcaagaggt gaagtttctt ttgaagaatt ggaagagatc
    11941 cataacaaaa tggagacact tcttggatat aagggcgctt atttggatgc agtttattat
    12001 tgcccgcatc atccacataa gggatatgag gaagagcgcc cagagctaaa attcgattgt
    12061 gaatgcagaa agccaaagcc cggaatgtta attcaggcag ctacggactt caacatagat
    12121 ttgagtcagt cttggatgat tggcgatggc gagaatgata ttaaagcggg ccaagccgcc
    12181 ggctgtaaga ctgcattggt tggcgagagt gagtatggac aggatatgac catagcaacc
    12241 ctgagtgaat ttgcagataa gatctgctaa gggatgtttt atcacgaaag gagagtataa
    12301 acaatgatag acaatagatt acagaaacac attgatttgc tgattaaacg ctatcccact
    12361 cttgaagtaa tcaagcagga tattgttgac ggatacctga ttatggagga atgctattta
    12421 aatgatggca agctgctgat agcaggaaat ggcggatctg ctgctgattc cgagcatatt
    12481 gcgggtgagc tgatgaaaag ctttaagacg cctcgccctg ttagtaggga atttgcagat
    12541 aaattgattg cggttgatcc tgtaaagggt tctgaattag ctaagaatct tgaatatggt
    12601 ttgatggcga ttcctctcgt tgctcatgaa gcgctttcca ctgcgtatat taatgatgtt
    12661 gatggcctag gtgttttcgc acagcagttg tttggatttg gaagacctgg cgatgtattc
    12721 cttggtattt cgacatccgg caatagcaaa aatgtgataa atgcaactgt tgttgctaga
    12781 gctcttggta tgaaagtaat tggcttaact ggagccaaag gtggagaact tgcaagggta
    12841 gcagatgttt gtgttaaagc tcctgaaaca gaaacatata tgattcagga gtaccatttg
    12901 ccaatttacc actgttggtg tctaatgttg gaagataaat tttttgggaa tagataaaat
    12961 atctaagccc atattgaaag gataaaatta tgaatgtact atttataaca actcaatttc
    13021 catatcctct agataatggc ggaaaaattg gtgcgtacaa cggtatcagt gttttatcta
    13081 gagactacga tgtgacggta ttgtctttca ccgaagaacc gcagtatgtt gaagaaggtg
    13141 tcagtttttt tcgagagaaa tttaatagtg taaaatttga aaatcctgtg atacatgatg
    13201 tacacataag aaataatcca atgaaattgg tagaagcttt agcaataggg tattgtctac
    13261 gccaacctta tatagtttca aagttttatg attcaaaaat gctgcagtta atagatgaaa
    13321 aattttctaa caatgcatat tgggatatca tttttattga ctatctgaat atgcaaagtt
    13381 atggtcaata catacgggag aagtataaaa cacaatttgg taagtatatc ttaaaagacc
    13441 acaacataga atatgattta gtcctacagg aagctgaatc aagtcgaggt ttaaaaaaga
    13501 agttgcttca gttagagtat aagcgtactc gaaagtatga agaggccgca gtaaataggg
    13561 ccgattattg ctttagtgtg tgtgatgcaa atacggaagt actgaaaaag attaatgaca
    13621 acagttatac gatgcttcca acttatgaaa tgcttacagg ggtgaaaaaa aatatagaga
    13681 agaacacgat cctatatttg ggtaaccttt cttggaaatc caatatgcaa ggattagttt
    13741 ggtttttaga gtcaatttat ccaaatattc aacaaagaat tccggatgta aaaatcacaa
    13801 ttgtcggtag cgggccagtt ggaacagatt ttagtaaata ttcaggcgtg gattatcgtg
    13861 ggtatgtaaa agatatttca cacatttatg acgatcaagc ggtgctaatt gtacctttgt
    13921 tagaaggtag tggtataaga ataaaaatat tagaagcgtt caataatgaa attgcagttg
    13981 tatctacatt agttgggtgt gatacgattg gcgcaaaaga tggaagtgag ttatttatag
    14041 cagataacga aaaagatttt gcaacggctg tagttagact gcttgaagac atgaatttga
    14101 atgaaaaagt aagaaagaat gcaaaattat tcttaaaaga aaaatactcc ttaacggcta
    14161 gacaagatga gtttagtgcg ataattaaca gctaatatat atataagctt atctgatgat
    14221 gatttatagg aggaaatata tggagatggc tgagagaaag gaaaagaaac ttggaaataa
    14281 gaatatcata ttattttaga aaactcctgt tattttatgt ttgtgtgatt gttgcggcta
    14341 tgagttacca ccttacaggc aattccaatg tagcgtcatt aattgctgta gtaggagtag
    14401 tttatgctat tgtaaaggcg tgtaataacg agtatctggc tatatgggtt atgtttgtat
    14461 taggttctga tatatggggg atagtgccat atattaacat tggtagtggt gtgttgcatt
    14521 ggtcagattt taatgttata gtagcgatat ttctctgctt gagattcatc aaagttaaag
    14581 ctaggagtag atacgggatt gtctatagtg taatgcttat atttattttg attgcatgtg
    14641 tgcaatcgca ttcaatctat ggacaagatg tacatacaac gctcttaaca gctagagaat
    14701 tgctagttgt aatatccttt tggccgatag taaaaatagt atattcagaa agaataacta
    14761 aaaatgaatt cattgattta gtgtgtaaat tcacaagatg gacaatgtgt atatattggt
    14821 ttgaatggat tcttgttaat atgggattca atataacctt tttacagaca ggtgcacgct
    14881 ggggtactag aatctatata gatccgatat ttatcatttt atatttcttt ataaatctat
    14941 atgcggttat atataaaaga gagggctata atagtacaaa taaaagtata tggaattgca
    15001 tttttagttt actgacattt gttataatct cgcaaggcag aagtggtata ttatatgtag
    15061 taataacctc ggttattatg cttttaattt cgcttaaacc atccaagatt attagatttg
    15121 gtatattagg aattgcctta attgcatgtc tagtgtctgt gacccaaatt agagaggtcg
    15181 ttatatcttc gtttgtagag tctcagagca gtgacacagg taatatcgca tatagaattg
    15241 ctgaacaaga ttattttgaa aataaattag aaggtcatga actatttgga gttggtatac
    15301 caaacaatca tgatgccaga gctgtagaat attcaggcaa aacaatagat tttgagtcta
    15361 aaaaatataa tccctattat cttgaggact taggcgcttt tgaaattcgt tatagatttg
    15421 gtataattgc atatgcgtta tatatagttg ctttagctat aagtattata gatgccggat
    15481 ttcgaagaga caaatcggtc gccgcatttg cgggtatggc attcatggtg tttatggcgc
    15541 ttaattttaa tttgctagcg tatattacag caagaccgtt cggatttatg atttctttaa
    15601 ttttgataga aatatcggca ttcaatgatg aattcatata tattgaatag gtaagggaga
    15661 gcacagatga atttagatcg attaaagaaa atagcaaata tgatttcacc aatcataaaa
    15721 gtgataaatg cgccgttagc gtattttagt gggaaatcag attatatgga gaagggaata
    15781 ttgtggccta ctgtaacaac ctactccaat aacagtagaa aagtgattca atatacaact
    15841 ttacctaaaa acgtagacaa catggctcaa atgcaatggg ctggggaaag ttttgaggac
    15901 atatgtatag ttcttcaagg tccagtatta gaagacggtg attttacact aaataccgtt
    15961 aaaatgtata ataaatacta tcctaaagta aaacttgtag tgtctacttg gataggatta
    16021 tctgaagaga cagaatgcaa gttgcgtgaa gctggtgcag atgttgtatt atgcaagaaa
    16081 cctgaaaaaa caggtgcgta caatattaat ctacaactta cttctgcata cgaaggcgta
    16141 aaaatggcgc aaaaactggg gtgtagttat gcgctgaaaa cgcgaactga tcaaagacta
    16201 tatgcaaatg atgtactaaa gtatttccaa acattattga atatttttcc atcttcggac
    16261 tgtaaagtag tgaatcagcg attaatattt acgacttatg gaaaatcatt tagatatctt
    16321 ccgtttaatt tatgtgattt tttggtatac ggagaaacta gtgaattatt aaaattatat
    16381 ggtattcaaa gagataaccg agcatcagac tttgggaaaa ttatttatac tgaggaaaaa
    16441 gagtttaata aaaagatatt tacactacta gaaggaaaac aaggtgtatc tccatatgat
    16501 gtttttccag attttgatgc actatataaa aaatatatgt ttgcagaata ctatattgtg
    16561 tataattatt tcctggaaaa tattgcaagt aatgaatctt atggtgactt aatggatgcc
    16621 tattatagtt atttaaagaa atatgcagtt gttgctgatt cagaaaaatt gttactatat
    16681 tggccgaaat atgttcaata taatgttaag ttcgaaaatg aacttgattt ctatgcgaag
    16741 ttggattcaa aaaaatggat ggatatttat gctaattata caccttttag tcagtgatta
    16801 tatggaaagg atgaggtgaa taatgaaaat cggaatagtg actattgtta atggggcaag
    16861 ttttggtaac agattacaaa attatgcgac tcaaaaagtg ttggaaaata acggctatac
    16921 agttgagaca attaataatt gttttgacaa agaaggtacc ctatccattg ttatcaaaaa
    16981 cgctatttat acattattta agtttatacc gcatttcaaa aagtcaaaaa gtatctggaa
    17041 aagaatgtat acattttatc aatgggacaa gcagtatata gattattctc atcgtaaaat
    17101 tgatgcatct aaaaaaaaca gctttgtgag tataaagaat gattatgact atttcttggt
    17161 tggtagcgat caaatttgga atccaaaata tgcagccaat aagggatttg aacttttatc
    17221 atttgttcca aatgaaaaaa gagtttcatt atcaaccagt ttgggagttc catctatacc
    17281 aagtgattta gaaaaattat atgtgacaga gtggaataag tttaaatcaa tatcggtacg
    17341 tgaaaatcaa gcggcaaaaa taattgagga cttgacaggc acaactgcgg ctgttcacat
    17401 tgacccaact ttaatgttgg agcgttcgga atgggaagcc tttcaaaaaa aaccagacaa
    17461 tattgatgaa aattacatct tgtcgttttt cttaactaat ccgcctaagg atactgttga
    17521 tgtattagat aaggtcgcta aagatttgaa aataggtgtt ctcaccttag atgcgtcttg
    17581 ggaatatttt caagatatta ctccgaatca ttttgtttat ttgatttcac atgcaagaat
    17641 gatttataca gattcattcc actgcacagt tttttcattg ctatttggaa aaccggttgt
    17701 ggtatttgac cgttttgata gtgaaaaaat gaattctagg ttaagtacat tgttaaataa
    17761 agtaaataaa gcacattttt gggtaggaaa aaaagctgat gaagcaatga ttcgtgcaat
    17821 agcatctgaa cctgaatatg acatagataa gctgatggta tcagagaggg aatgtgtaaa
    17881 agcttatctt aaagagtatt tacagtaaaa ttttgaaatg ggatgaaaat atggagcatt
    17941 taagtgattg ttttggtaaa atgaagattg ttacgacttc atgcgcaaga gaatatttta
    18001 aggatgattt ggataaatca gagtattcat gttttgttga ttctcgagca gctatgtttt
    18061 tcgcaatggg acaagcttta gctaaaagaa ggaatgtagt tgtaatgctt gctgatgaat
    18121 tgacatcgtg ttatacggca ctaacagaat gtgcatttca acaagttgat ttaattgtgt
    18181 ttgcttttca gacagtcaga catgaaattg atttagcatc tttgaagaat tgtggttgca
    18241 atctaattaa ctgtagcgcc caagacgata ttgatagagt tgtgtccaac actaaggggt
    18301 taaatcagac aacagtaatt aaaatcaata tgaattgtga gtcggataaa gatcatatat
    18361 gtgagtatat agacctgcca gacatacctg tttttttcca cggtagctta tactcacctg
    18421 caagtaaaaa gaaatatgag cagtatggac aggtatcgaa gtatttaggc tatctcgtgg
    18481 ggggaaaaga tgcaatactc ataatttctc acaatgagtt tttaaacgat atcagtgtat
    18541 ggattaatta ttattctttt ggagaaattc aacccaaaat tattatattt gacagtccga
    18601 atgactatca atataaatgg ctgtgtgact tagaatgcag tgtagctcat tcaaccaacc
    18661 gatttttgtc tgaggattta gccttattgc aaaataacgg aatttccatt gtgttaagag
    18721 gtgataatta tgatatcgtc agttaaaaat gttcaaattt tagtatcttt attaaaacag
    18781 cataatatta aagatatagt tatctcgcca ggtagtagag attttcaatt ggtgcatagt
    18841 gtagaaacag acagtttttt tagaacctat acggttgtag atgagcgcag tgctgccttt
    18901 tttgctaatg gactttctat ggcgattgat aagcccgtgt gtgtatgttg tacttcttca
    18961 actgcctctt caaattatat ggcggcagct aaagatgctt ttgctaatgg catccaactt
    19021 gtacttctta ctgctgatag agattaccgc cgcttatatc agatggaaga tcagatgatt
    19081 gatcaggtag atatgtatgg ggcttatgtg cgttctaacg ttgatattcc tattgttaag
    19141 gattctgatg atgaatggta tgctaccaga aaaataaatg aagcaatatt ggagttaaat
    19201 catggcgtta agggtcccgt gcagattaat tatcaattaa tggatttaag tgcgccgttt
    19261 gttgagacca tgccagagta tcgtaaaatt acaagatatc aagaggatga tttactgtca
    19321 tcagtagaga tttttaaaca gaaactatta tcaaaaaaga gaataatggt tttatgtgga
    19381 cagcaggaag aaaataattt aagtgcctta ttggaagagt tctttattaa atataataca
    19441 attataatca aggataacta ttctaatata cacggtgaac actttattaa gactgttcta
    19501 gtaacagaaa gaatgagtgt aaatgcattt attgattatt gcccagattt ggtaataact
    19561 attggtaaac atgtatggtc ttttgtgaaa tatactctta gagataaaaa gcttaaattt
    19621 gagcattggc ggatatctga ggatagtaag attgttgatc cgttcaacaa gctaacatct
    19681 gtctttcagt gctcagcgga attttttatg gagactgtca ctgctggtgt gaatagcaat
    19741 aataatcttg agtattataa tctatggaag acaagattat caaaagtttg ctatccagag
    19801 ttagtctata gcaattttta tgcaatttca gaactagtaa aaaaaattcc agatagtgca
    19861 ttagttcatt ctagtatttt aaatgcggct agattgtatg actttgtatc tgatgataaa
    19921 gcattactca gttttgctaa tttaggggct gatggtattg atggttgttt accaacattt
    19981 ttaggtcagg cagaagcaga taaaactcga cctgcgtatt taatttcagg agacttgagt
    20041 ttcttttatg ctatgaatag tttatgtggt gacattccag ataatgcaca tattttcctt
    20101 attaacaatc attctggaag tgaattccat acaaattttg gtaagtttta caacggatca
    20161 ttaagtgttg ataagcatat agctgcagga catatttcaa acgcaaagga ttgggcatta
    20221 gaaaataata taaaatacat tactgcggat tctaaggaaa gtctcaaatc ggggttggat
    20281 gtatttatta atacatttga cagtcctgtt ttatttgagg tctttacaga tccggatacg
    20341 gatacgtctg ttctggaatc tttttatagt ataaataagg taatcacacc aaaaatgtat
    20401 tttagaaagg cgttagatat tataaaaaag catttacaca ttaagtagat gtttattgcg
    20461 aggtgaaaca aatatggcaa taaaatctta tattaaacgg ttattgcttt atatccgtca
    20521 tggagatccc aaaataaatt tagatgtgag ttatttatct gaaggtgcaa tgcttgctgg
    20581 taagactgtg ataattacgg gtggtgcaaa aggacttggt tttgcaattg caaaatcatt
    20641 tatagctcaa ggcgcaagcg ttattattac aggaagagac atggattcgt tgaataatgc
    20701 taaatgtcag cttggagata tgtgttctat cagggcgttt gatataactg atgctaaaat
    20761 gtatcgaacg ttttttgaag atgcatacga gacctttgga cgtattgata tactgcttaa
    20821 taatgctggg atctcgttac acgaagatgg atttatgagt gttactgaga aaacttggga
    20881 taagcaaatg gatacaaatt tgaaaggtgt ttatttcttt acacaggaat ttattaagtt
    20941 tgttaaagaa aagaatcaaa tgcaagcaaa tattattatg atgtcctcag aaagaggctt
    21001 gtgtggtgat agtattccgt atggattatc aaaggctgca attaactctt tagttgtagg
    21061 cttgtctaag aaatatattt ctgagggaat tagggttaat ggtattgctc ctggagtaac
    21121 tgcaaccgct atgactggta tttctgaaaa gggtaatttg tataatcctg caacgatcgg
    21181 ttatagatat tttctcccag aagaagttgc tcaagttgct ttgtttttgg caagtagtct
    21241 ttcaaactgt atcagtggtg aaatcatagc ctgtgaccag gggcaatatt taagtcgaaa
    21301 ttgggggtaa taacttggga atattattaa aaaaatataa tagccttagt gagcctgcaa
    21361 aagcatctat ttggtttaca ctttgtaatg tgttgcaaaa aggaattcta tttttgacta
    21421 cacctatttt tacaagaatg ctttcaactg cagaatatgg taagtatacg atttttatat
    21481 cgtggtattc tattatagca attttcacaa cgttgaattt atctgcaggt gtctataata
    21541 aaggactaat taaatacgag aataaatatg cattaacctc gtcattttta ggattatcgt
    21601 catttatttc cctttgtgca ttgatgctat accttccatt tagaacggtt ataaatgggc
    21661 tactggattt atcgacggag tttgtcatat tgattcttat tgaatcaata tttgagccgg
    21721 cttttttgct ttggtcagtt aaggaacgat ttgattacaa gtatcaaaaa ctagtactca
    21781 tcacagttct tatggctgtt ttaaatccag gtctcggtat tatattaatc ttatcatttg
    21841 gggagtatgc tatttggaga gtacgagctt atgtcgtggt aaatgttgta gtggggatgt
    21901 ttattggcat aggaatactg gctaagggta agaaattatt tgataaagag tactggacat
    21961 atgcgctcag atttaatttg ccattaatac cacattattt atcaatgaca ttgctgaatc
    22021 aggttgatcg ccttatgata aatagtatgg ttggagctag cgaggctgcg atttatagta
    22081 tcgcttacac tatatctagt atgatgaata tcataacaac agctataaac ggttctttta
    22141 ttccttttac atacaaagca attaaagatg gcgtgtatga aaaaattaaa tccgttgcta
    22201 atcaactatt agtgttgatt tttgtcttgt gttcgtttac tatgctgttc gggccagaat
    22261 tgatttgggt tgtcggagga gaaaaatata tggatgctgt ttggattatt cctccagttg
    22321 cggcatcagt atttttcatg tttttatatc cgctttttgg caatattgaa ttttactatg
    22381 aaaagacaaa ctacgtaatg tttgcatctt gtgtgggctc tatcgcaaaa attatttcaa
    22441 actatgttag tattccccgt tttggatata tttcggctgg ttacacgaca ttgatttgct
    22501 atatgttgtt ttcctttgcc cactacatgt tttataaaaa aattcttaga gaaaatggta
    22561 taaaagaaga tatgtataat attaaaaata ttatatttct ttctgtctta atgattgtgt
    22621 taactattgg tatgacaata ttatactttt ctacaattct aagatatagt attattattg
    22681 gattagttat tgtggctttt cttaaaagga cgcaaataat gaaaatcctt aaaaatataa
    22741 aaaattaaca agcaaatctt gggaatggaa cggaggcacg gtgaaatgag attattgatt
    22801 ccatctgcta agattgtacc ggaagaactt caccatcttg gaaaacttcc tgcaattatc
    22861 tatccgatta atcaaaaaat tgtatttgat tatttatatg atcaatataa agatgtatgt
    22921 tctgctatcg atattgcctg ttacgaaaag atggataagg tagcaagacg attagataag
    22981 tatattaaat ctaaaacagt aaatattatt cagcttaaag agttagggga tcttggaaga
    23041 actatatatg attctctaat aggatgtgac gagcctgtta ttattaattt tgctgatacc
    23101 attatcaatg ataatatata ttccttggaa tgtgacagct ttttctatgc tgaagactat
    23161 tatagtaata cttggacatt ctttgaagaa aaagacggag atattatttc tgttttagat
    23221 aagaacgagt taaaagaaga tgatggaaag aagcacaaac tgttttctgg tgtatttcaa
    23281 attatggatg cccagtattt tagagagtgt ttgcgtaaag ctttgatgtc aaatgtagta
    23341 aatgtgaata gtttttatca agctttacaa gagtatagca aacgatatga atttctctct
    23401 attaaaacaa ataattggtt tgacattgga catgcagata aatattataa ttccaaattg
    23461 gaagttaagg caagagaatt taaccacatt tcaattgata aagatcgtag catcctgaga
    23521 aaaattagtg aagatgttga aaaatttatc ggagaaatta agtggtatct taagttgcca
    23581 gcacaggtag aatatgtgag acctagaata ttcgaatatt ctacttcgta tattaatcca
    23641 tatgtaagta tggaatacta ttcgtatcat actgttcacg agttatttct ctatagtgac
    23701 ttaacaaaaa aacaatggat agatatcttt aatagaatac gatttgtatg ctcagacttt
    23761 aagagatact ctgtttcagg ggataatatt caaaagtcat tgaaagatat gtatctcgat
    23821 aaaacatttc agagattcaa taagctcaga aaggaccccc ggttcacaga attcttttct
    23881 tctgatattc aaataaatgg agtcagatat aaatctttgg accagataga agctttattg
    23941 agcgtaagtg ttccaagaga attgtttgac attacgcaat ttaatattat tcatggtgac
    24001 ttatgctttg ccaatattat ggtagataac acattttcgt tcattaaagt catagatccg
    24061 cgaggtaagt ttggagattt tgatatttat ggtgattata gatatgaact ggcaaaattg
    24121 tttcatagtg ttgatggaaa atatgacttt ataattaagg acttgtttac aataaaatat
    24181 gatccaaaga aggcaatcat agactatatt gttcaagatc gtaaacgaga ttatgattta
    24241 tatgaagtat tttactctgt cttcaaagat gaaataggtt ctgatttgaa aaaaattgaa
    24301 cttattgagg ctttgctgtt tttaagtatg attcctttgc atggagaaag cttaaaccat
    24361 cagatggcta tgttagcaac tggtttggaa attttaggac gagttgtccc ggatatttat
    24421 tgttaatgct ttgagctatt gtttttctat ttgatcagtg taaagccggg catataaatt
    24481 gcctggctaa aataaaggag atgtcttagt tatatgttta aagattacgc atttgttttt
    24541 gatattgatg gaactttgtg ccccatcaaa aagaaagatg agaaatatga agatttagtt
    24601 ccgtatgcta atatggtgga gaagttgcga tactataagg agaacggagc aaagattaca
    24661 ctgttcacat ctcgcaatat gaattcttat catggtaatt taggtgtgat caatgcaaat
    24721 actgcaaaaa tcttgttggc ttggctagat aagtgggaga ttccgtatga tgaaattctt
    24781 tatggaaagc cttggccagg ccataaaggg ttttatgttg atgatcgcac agttcgtccg
    24841 gatgaatttt tatcgtgtac cctggatcag ctcgatgaga tttgcaaaaa atccaaattg
    24901 aaatctgagt aaaggagact ttataaagtg aataagatga cggttattat tacaatggct
    24961 ggtcttggca gtcgctttcg taaagttggc tacactgtgc ccaaatttat gattgaagca
    25021 aaaggtaaaa ccttatttga ttggtcctta gacagcttgc ttgattataa ttcacatgta
    25081 gaaaagtatg tttttgttgt gcgtaaggaa gatgatgcta ctgtttttat caaagaacat
    25141 tgcagtctgt atggaattga aaatgtcgag gtagttgaaa ttgactatat gactgatgga
    25201 caagccacta catgtatgct tgcaattcct tattgcgcac ctgataatgc aattatggtt
    25261 tataacatag atacatatgt tgagccaggt gagatgaaat acgttgatat ttctggagaa
    25321 ggacatattc cgtgtttcca tgcggacggt gatcattgga gttttgccaa gttgaacgaa
    25381 tatggtgatg tagtagaagt aagagaaaaa gttagaattt ctaacaattg tactttaggt
    25441 gcatattatt tttcttctgc aaaattatat gcatcactct acgaagaata ttatgcagat
    25501 gaaaggcatc tggaaaagaa tgagaaatat attgcgccgc tatataatta tatgatagag
    25561 aagggcatga aggtaaccat tagtatagta gataaatcaa aagttcacgt actcggtact
    25621 ccagaagagc tcgatgtgtt cttaaatgaa tagggaaaat ataatcatag aaaatgttaa
    25681 ttataaagct gcgtgtgtgg gggagtacta ttcgatagat attctaaaaa tactaatggc
    25741 tattttagtt gttgttcgtc atttaggtca aaactattta gctccagatt aagcatttag
    25801 tattggtatt gttgcaggac tgagtacggt tgccgttcct acttttttca tcatcagttc
    25861 ctttttgttg tgtagtggtg aagttacatc cgctaaatta tctaaacaaa tctacagagt
    25921 acttaaaatt tacattattt ggtctatatt atatattcca ttagtattaa agaattgggt
    25981 acagtcagat tttagctgga aaacagatgt attattgtat atcagagatt ttctgtttat
    26041 tggtagttac tatcacctgt ggttcttgcc tgcactggct tttgctctat ggttagtacg
    26101 caaaagccag gtttctaaaa taaagtttct cagtggtttg ttgctatgcg tagtaggttt
    26161 agcatttgaa tcttattggt ttatattatc tgggaatgat tccatcgagt atattagata
    26221 ttgttataaa agcgtgtttg taacaactcg taatggatta tttataggtg taccatgcgt
    26281 cattattggg caacacttag ccttccacaa aaacactata cttaataagg tctttaaata
    26341 ccgtaatttt atcttatgtg ctgttttagc tataggatgc ttattagttg gtgaaagttt
    26401 catcataaat caaatagctt tgcgagaagt caataatttg ttaatatttt ccattccatt
    26461 agcactggta gttgtatcag tatcactgag cctaaagata gtacatttat aaaaataaca
    26521 gtacatctgc gaagaattag tacgttatta ttttgtttac atccgtatat aatagctgct
    26581 ttaaatttta ttttcccaaa attggggatt acaaattcat taatagaaat gacttgtgga
    26641 atgataataa ttttaatttc tacagttttt gtgtatgcgt gtagtgtgaa atttaccttg
    26701 ctgaaaaaat tatattagat tagtaactgg tacatgtaaa tttgttgaaa ttatagcagc
    26761 atagagatag gaattctgtt gagttttatt ttcgctggcc gaggttattc atgttagagt
    26821 gggtacctcc ttttacgaaa ccttcttgat ggtactcatt tagcgcatga tgaaaggaga
    26881 gtttatgaag aaaatcatat cttctatttt ggttaatgtg ttatctgcat tgtatcaaat
    26941 atttgggttt cgattttaat tgcagttttg gctatgtttt tatacttgtt tgcgatggct
    27001 gaggagaaat caggattagg tttgaaaaaa tcttttcttg tctggattcg gtatttcaga
    27061 aaatcaagct catttagaaa aatgtttttg cttgtgtttt ttacaaatat gattcttttt
    27121 agaacactga tggatagata tgtttggcta aatcctttgt ctaatgtgtt tggtagttgg
    27181 tggatttact ctgtgaatga aacgacaggg gagattagat taactacaga atgttttgaa
    27241 aatgttattc tgtttattcc atttataatt ctagtaatgt ggtataaggc ttcagaaaaa
    27301 gattttggaa aaatttatca gagattataa aatttgtttt tttatgttcg tgtcttatag
    27361 agtttttgca gttattttta cacatagaga cattccaatt gtcagattta ttttataata
    27421 ctttgggtgg cggcattagt ggggttatat attatttgag ctgatatatt catcctaacc
    27481 ttaaaaataa atgagcagaa ttttaaaaga ttggagagat tctatggatc ataatgcaaa
    27541 ttattatcat tggcttacaa atgccaatgc agaaattgta gaggaactgc ggtcatattc
    27601 cgagaaggac attgaggact ccttctataa aaatctgtcc tttggtaccg gtggtctgcg
    27661 tggcaccatt ggtgcaggca ctaatcgtat gaacgtacac accgtaggta aggcaagcca
    27721 gggactgtca gactatctga ataagaccta tgaaacccct tctgtcgtcg tgggctatga
    27781 ttcccgaatc aagtccgatg tatttgcaaa ggttgccgcg gacatctttg ctgcaaacgg
    27841 tattcaggtg catctgtggc cggagctgct gcctgtgcct accgtatcct ttgctatccg
    27901 ttatctgaag gcttctgccg gtgttatgat caccgcatcc cataatcctt ccaagtataa
    27961 cggatataag gtctatggcg caggcggctg ccagatcacc accgaggctg ccgctgagat
    28021 tctggctgaa attgaaaagc tggatatttt tgcagatgtg aaaatgggcg gcgacgcttc
    28081 cagaatcgct tctatccagc cagaggttct gactgctttc attgaagaag taaagggcca
    28141 gtcggttctg tttggcgaag aagtggacaa gaatgttgct atcgtgtatt ctcctttgaa
    28201 tggtaccggt ctggtgcctg ttacccgtac tctggcagaa atgggctaca gcaatgtgac
    28261 cgttgtcgaa gagcagcgtc tgccagacgg taatttcccg acctgtcctt atccgaatcc
    28321 ggaaattaat gaagctatgt ctctgggcat ggagtatgcc aagaagtata atgctgatct
    28381 gctgctagct accgaccctg actgcgaccg tgtgggtatc gccgtgaaga atgcagaagg
    28441 ggattatgtc ctgctgtccg gtaacgaaac tggtctgttg cttctggact acatatgctc
    28501 tcagagaatt aagcacggca agatgcccac tgaccctgtg atggtcaaga ccatcgtgac
    28561 tatggatctg ggcgagcgga tcgcttccaa ctatggcgtg cgtactgtcg atgtgttgac
    28621 cggcttcaag ttcatcggcg aacagattgg tatgctggaa aaggcaggca aggtggacag
    28681 ctatattttc ggctttgagg aatcctacgg ctatctatcc ggcagctatg tccgtgacaa
    28741 ggatggtgtc aacgccgctt atctgatctg cgagatgttc tcttactaca agactcaggg
    28801 tatcagtctg tttgataagc tgaacgagat ttatgctaag tatggctact gtttgaacac
    28861 cctgcattcc tttgagtttg agggtgcggc aggttttacc aagatgcaga aaattatggt
    28921 tgaattccat aaaggtcttg atatgattgg aggtaagaag gtcattgaaa ccttggatta
    28981 cagcacggga ctgaatggcc tgccgaagtc tgatgttctc aaatatctgc tggagggcaa
    29041 ctgctctgta gtggttcggc cttccggcac tgagccgaag ctgaagacct atatcagcgt
    29101 tagcgcagaa agcaaggaag ctgccgaagt aatggaagct gttatggctg ctgaactggc
    29161 tgaaatgttt aagtaatact atgaaaaaga tctgagtgtc aatgtccgaa gtagcaacat
    29221 ctatgtttaa taaaaatttc ctgctttacg gttctgttta cataattgag gtaaaggggc
    29281 cgactgtgtg gatcgaaaag gcaaagaagt gttaacagag acacagcagc ctgatgaagc
    29341 accgatcaaa gcagtaaggg agaaataaga gatattagag ttttaataat gtattcagca
    29401 atagagatga aaggagtaga atatgaataa aactattgaa ataataaaat gagggggaaa
    29461 gaaataaacg tgatattatt agttttgaga aggcgttttc aatattcgct attgtattga
    29521 tgtactattt tcagcaatcg tatttgccag caatactgaa caaagcaata tctattggtg
    29581 atacaggagt gcatatattc ttcttttgct caggttttgg gctatatctg tcatatttaa
    29641 aaaagcctat tacattgggt gaatttttac agaaacgatt tatcaagatt tatattccgt
    29701 atattatcgt aattacggta tcagtgttac taccttatat gacacaagat ttaaatgctg
    29761 caaaagtata tttgtctcat gttttgttat ttaaaatttt tctaccagta tatgaggagt
    29821 cactgggtcc ctttggttta tttcgacaat tattcagttc tatttcttat tcataccaat
    29881 tgtaaaacta tagagaaaaa taggaatgaa atgattgctt gttgcaagct gagttattag
    29941 tatctgggct attatgatgt ttcatacagg atatggaagc atacgagttc ttgggagctg
    30001 ctttgcgcaa tatatttggg aatttacttt cggcatgttt ggttgcagag tatttagtga
    30061 aaagaaaaat agtaagattt aataatatat tcgtgattat ggcgtccatt gttggaattg
    30121 gttttgctgg tatatcgaaa attattggtg gactgatgga gtctattaat gatatttttg
    30181 cattcttcgg ttacggtgca attgcaattt taatgtatca agttattcca tttagaaaga
    30241 taatgcctag gatttcaaga tactcatatg atatatatct actccatatt cttgtattta
    30301 gtacgattca tcaaattatc cctaacttgg ttttggcggc atttgtttcc attcctataa
    30361 cgttggtgtt gtcatattat tatagtatta tgttatatag acttaaatta aaatgatagc
    30421 ataattgtcg cctctaccgg gcggttgcca tcctgattaa cagcctccac gcggcggatg
    30481 gtgggcactt aggtagttcg taacctagtg gtagatggtt ggtaaaaagg agataaaact
    30541 aaatgattac acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
    30601 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
    30661 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttct
//
LOCUS       DARPZJ010000027        30509 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.028, whole genome shotgun sequence.
ACCESSION   DARPZJ010000027 DARPZJ010000000
VERSION     DARPZJ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.028"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            53..742
                     /locus_tag="SLE23_001536"
     CDS             53..742
                     /locus_tag="SLE23_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEI8468446.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            748..1914
                     /locus_tag="SLE23_001537"
     CDS             748..1914
                     /locus_tag="SLE23_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HEI8468447.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            1996..2667
                     /locus_tag="SLE23_001538"
     CDS             1996..2667
                     /locus_tag="SLE23_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEI8468448.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            2720..4696
                     /locus_tag="SLE23_001539"
     CDS             2720..4696
                     /locus_tag="SLE23_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEI8468449.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            4709..5461
                     /locus_tag="SLE23_001540"
     CDS             4709..5461
                     /locus_tag="SLE23_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8468450.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            5477..6238
                     /locus_tag="SLE23_001541"
     CDS             5477..6238
                     /locus_tag="SLE23_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468451.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            6251..6511
                     /locus_tag="SLE23_001542"
     CDS             6251..6511
                     /locus_tag="SLE23_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468452.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            6508..8598
                     /locus_tag="SLE23_001543"
     CDS             6508..8598
                     /locus_tag="SLE23_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEI8468453.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(8634..10691)
                     /locus_tag="SLE23_001544"
     CDS             complement(8634..10691)
                     /locus_tag="SLE23_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEI8468454.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(10696..10896)
                     /locus_tag="SLE23_001545"
     CDS             complement(10696..10896)
                     /locus_tag="SLE23_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468455.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAEFNHLIGS"
     gene            11084..11539
                     /locus_tag="SLE23_001546"
     CDS             11084..11539
                     /locus_tag="SLE23_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468456.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVSYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            11536..11778
                     /locus_tag="SLE23_001547"
     CDS             11536..11778
                     /locus_tag="SLE23_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HEI8468457.1"
                     /translation="MIASLFIYPEGGIAVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            11796..12098
                     /locus_tag="SLE23_001548"
     CDS             11796..12098
                     /locus_tag="SLE23_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468458.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQGAATSLKNNLMIFAAVAA
                     VASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGMFGQTPQGL"
     gene            12167..14221
                     /locus_tag="SLE23_001549"
     CDS             12167..14221
                     /locus_tag="SLE23_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468459.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            14221..16833
                     /locus_tag="SLE23_001550"
     CDS             14221..16833
                     /locus_tag="SLE23_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEI8468460.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            16830..19208
                     /locus_tag="SLE23_001551"
     CDS             16830..19208
                     /locus_tag="SLE23_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468461.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            19269..19811
                     /locus_tag="SLE23_001552"
     CDS             19269..19811
                     /locus_tag="SLE23_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468462.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            19889..20221
                     /locus_tag="SLE23_001553"
     CDS             19889..20221
                     /locus_tag="SLE23_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468463.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            20222..20815
                     /locus_tag="SLE23_001554"
     CDS             20222..20815
                     /locus_tag="SLE23_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468464.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            20837..22861
                     /locus_tag="SLE23_001555"
     CDS             20837..22861
                     /locus_tag="SLE23_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEI8468465.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            22861..24060
                     /locus_tag="SLE23_001556"
     CDS             22861..24060
                     /locus_tag="SLE23_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEI8468466.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            24076..24720
                     /locus_tag="SLE23_001557"
     CDS             24076..24720
                     /locus_tag="SLE23_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468467.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPVDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            24731..25537
                     /locus_tag="SLE23_001558"
     CDS             24731..25537
                     /locus_tag="SLE23_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468468.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVAEDQENTENKINSYQQEIETSKTQMKDQEESIQKLQEKIDRMTKENI"
     gene            25560..25789
                     /locus_tag="SLE23_001559"
                     /pseudo
     CDS             25560..25789
                     /locus_tag="SLE23_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25810..26883
                     /locus_tag="SLE23_001560"
     CDS             25810..26883
                     /locus_tag="SLE23_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4199 domain-containing protein"
                     /protein_id="HEI8468469.1"
                     /translation="MKKTYQKFLWISYIVLFIVGFLVSVSVIVGTLFLLFSDEDLVLK
                     GLMSTLSCVMLLYLCIQINEIMPPHWQEKKKEFKEEIEIKSNDWIEYTWLPLKRNSKR
                     KEFWALQLWPIGKLFIYMASLMVTLIGYLVVVYGVAYYLLSEPKQIAASNIFTAVMTL
                     MCVMCFSIFSYLLVQFIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIK
                     NFLTTIDQFINGYMYLFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVD
                     FGKYEELIHTDIVHTSIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGI
                     GKLRLDGSNIQQNKPYVLGKVVI"
     gene            26927..27196
                     /locus_tag="SLE23_001561"
     CDS             26927..27196
                     /locus_tag="SLE23_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468470.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            27472..27747
                     /locus_tag="SLE23_001562"
     CDS             27472..27747
                     /locus_tag="SLE23_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468471.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            27789..28211
                     /locus_tag="SLE23_001563"
     CDS             27789..28211
                     /locus_tag="SLE23_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468472.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            28231..29823
                     /locus_tag="SLE23_001564"
     CDS             28231..29823
                     /locus_tag="SLE23_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468473.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            29844..30179
                     /locus_tag="SLE23_001565"
     CDS             29844..30179
                     /locus_tag="SLE23_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468474.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            30325..>30509
                     /locus_tag="SLE23_001566"
     CDS             30325..>30509
                     /locus_tag="SLE23_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468475.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        10943 a         4769 c         6204 g         8593 t
ORIGIN      
        1 gtttatcttg gttagatgta ggtaaattaa ttcatatata gaaggtagat agatgaataa
       61 aaacaataaa actttattta atccttacgt gggcgtaatc attgtttttc ttctttttag
      121 ttattttgct tatcaaggtt atcaaaagga caaaatcgct gaaaaagtag atggtgtaac
      181 aaaaacaatc catattcagg aacaggctaa aacctatcaa gataatttaa ccagtttaac
      241 ggatatttct aagagacaac tgattactaa tcaaaaacag gcattagaaa aggatctcaa
      301 aggtgaaatt gctggaaaac ttgttttttc ttctacagga tttattctcc ctgtttttca
      361 aggagcgaat agcgacacgc ttagtttagg agtagcttct acttattatc tagatactga
      421 aatgggaaat ggaaattata ttcttgctgg ttataacgta gatacaccaa gcgttttatt
      481 atccgatatg actgatttat ctgaaggaga agaaattgat ctaatcgatg ctcattacaa
      541 gtatcagtat gaagtctcca aaagaggaaa aatttctgat tacagccagg tagttcaatc
      601 taaggaaaac aattcctttt tatccttgcc aaaagcaggt aaaaaaccac tactcacact
      661 gttagccttt caagcaaata atatgaaaaa gtgcgatgtg atccagtgtg aattagtcaa
      721 tgtagaaaaa atcaataaat aagggaagtg agtcacattc aagaacttgt agaaaaattg
      781 atcaataaaa tgagtgccat ttttctgtta ctgttggtat ccattctata tttaatatgg
      841 acggtggggt taaatcctcc tacgatatta tttatttatg ataatgctgc acagttagtg
      901 acgtttttcg taggctgttt gtttcttttg aatctgtaca aggtaaagag aaacgatcta
      961 ttcttcattg cagcaggcat tcttttttac cttttctttt ctttttttag aagctaccga
     1021 ggagatactt tctatggtga tctgatcgtt ccgacaatta ttgctattat tttgattgta
     1081 aaatggacga aatttactgt aattgatcgt agcttgtatc ttgtagtatt ctatgtcttt
     1141 ttactcgtaa cggtttatcg agtatttact gagataccag taccagaagg acaaagtatt
     1201 tggaatccat cgaacaaatt atcagatatt tggatcaata caaatacgat aggtagttct
     1261 ttaatgacat tagcccttct tatcacagga tttgctagtt catttggaaa atggtacatg
     1321 cgattgctat cattaccagc gttgattctt gctggggcaa cgatttgggt ttgccaatcg
     1381 aaagcagcat tatatgcgct tgttatcttc attatcttag aaattttacc taagaaggtt
     1441 tttcgaaata cacacttgtc cttttggatg tatgcagcag tttcggttct agctttaccg
     1501 atttcttatt ttgctgcaat gtcagacaaa gttcacttat ttacaggacg agaagaaatt
     1561 tggcgcaaat tctatgaaac attaggcgaa aaaacaggac aaatatttgt agggatgaaa
     1621 cctttctttt tccatagagg aaatcagatt ctaggtaatc ataatacgta tcacgcactc
     1681 gtcaatcact atggattgat tggttttgtt ctatcgatta ttcttttgct tagtttctta
     1741 tggttgctcg taagaaaacg tgagctgaca aatggacaac taacattctt gtgggctttt
     1801 ttagcgatca tgtgtcaatc gttcatggaa gaaacattaa cgacaatcag ttgggtgcca
     1861 attgtattct taatgttagc aatggctaca caccaatata aaaccaccag ataaatgaaa
     1921 tagaatagta ataagagaaa acactttttc gttgtgaaaa agtgtttttt gttttgtctg
     1981 aaaggaggca gatggatgaa aaaatggtta tttggttttt taggagtcgc tttaatcgtc
     2041 gtttgcagtg tgtttggcta tgttagctac caaaaacatg aaggagaggt gtttaagcaa
     2101 aatatagaaa aaaagatgcc cgtagatcaa atcaatgcac acgcaaagag ttataaggag
     2161 gatgcaacga acgtcaataa tgatatgtct ttggggcaaa tgttgtccat acaaaaagaa
     2221 gcaatcgaaa tgggcgtcaa taaacaagta tttgcacaaa ttcagattcc tgcacttggt
     2281 ttagcattgc caatttttaa aggggcaaat caatacactt tgagtcttgg agcggctact
     2341 tatttttatg aagatgccga aatgggtaaa ggaaactatg tcctagcagg tcataacatg
     2401 gaaatgccag gtgttttatt ttctgatatt caaaagttgt cattagggga ggtgatggac
     2461 ttagttagta acgatggcgt ctatcgttac aaggtaacgc gtaaatttat cgtacctgag
     2521 tactttaaat taatcgatgg cgttcctgaa gagaactctt tcttgtcttt accaaagaaa
     2581 ggagagaaac ccttattaac gttgtttact tgtgtttata cgtcacaagg aaaagaaaga
     2641 tacgtggtac agggagagct acaataacaa gaatttaatc aacgcgagtc gttgaaatat
     2701 gaaatgagga gagtaaaaaa tggcaataaa tcggtatgta aaaaaagctg gaatgattgt
     2761 tggaatgtta ggaatcattg caggctgctt tcaggggtat cgagcttatg cagaagatgt
     2821 cacgcaaaaa acgccaccag aaagggtcaa tatcacggtt cataaattaa tgtacgatca
     2881 aagtacgcaa ttgaacgttg atattgacgg aatcaaaaat gatggttata cgcacgatca
     2941 atatcctaca ggtgtaacga aatacaacaa ggcagattat ggtgatgttg agtttacgtt
     3001 aggaaatatt acggatcaag tattaccgac tgaagattct gatctaacca acgcgaaagt
     3061 ggacgaaatc gttaaagatg tagaagacaa gggatctaac agtgagtacg ttaagaatgc
     3121 aaccaataaa attacttcag ctgtagatga aaatggtgag atcacttttg ctgatcaacc
     3181 agcctatgtc aattccaaag ggaatgtata tgtggtttat gaaagtaaat ccgctgctgg
     3241 attagtcaca caaaaagcaa aaccaatggt tgtgattgcg ccaatgacag acaacacagg
     3301 atcaggattt ttaaaagata ttcatttgta tccaaagaac attgtttcta agttgagttt
     3361 tgaattaacg aaatttggtg acgatggcac agctcaaagc aaacaaacac ctttaaaagg
     3421 ggcaaaattt gagttataca agggcgaacc tggaaaagga acaaaattag gagagcttgt
     3481 atcggatgat caaggaaagc tgactgcaac tgatttgacg ttaggaaaat actactttgt
     3541 ggaagttcct tcagaagttg tagttggatc agatcaagaa ccaacagcag accaatattt
     3601 gttaggcgca gacgctcgca acgatgcgca caataagtta acctttgaaa ttacgaatga
     3661 cggcgtgaca agtgatttaa aagcttccta cgtgaactat aaagcaccag tgatcgataa
     3721 aacagtgaca aatggaacag gagaagaaca ttctttccaa attggtgacg cagtgaatta
     3781 tcaaggtaca attcatatcc ctacagatat cgcaggtgga acagatggga ttacagtaaa
     3841 tggtgtaaaa agtgaaactt ctccttacag tgtatttaaa tggggcgaca cagcaggtaa
     3901 aggactttct tatgttgctg aaaaagcaga tattaaagta acaaataatg atggttcagt
     3961 cgtattaaaa gaaaatactg actataaaat cgaaaattct gatagtggtt ttgtgatcga
     4021 ttttatcgta aataatggac aagtaagtga tacagttgcg aatttacatg gtcaagatct
     4081 aaaaatgact tataacatgt ttgtgaatga tagtgctgaa atcgcaaatc cattaacaaa
     4141 tagcgtggat ttcgtttata acaataatcc atttaatcag gaagaacacc acgaaaaaac
     4201 gaaagctgac gttgtgactt atggcgcaaa attcttaaaa gtcgatagcg gcctatttgg
     4261 aacaggtatc aaagcaacac cgcttgaagg cgcagaattt gcagctaaga atgcagaagg
     4321 taagtactac ggtggactta ctgatacaga taaagatggt gtcaaagaag cagtttgggt
     4381 agacgatgta gcaaatgcag caatcctaaa atcagataaa gagggtcatt ttgaaatcac
     4441 tggtttaact gaaggagatt actcactgga agaaacaaaa gctcctgaaa actatcaaaa
     4501 attaacaaaa gagatctctt tcaaagtaga caaagattca tacaaagaag aaaaccgaat
     4561 cacgatcaaa aataatcaaa aagcttccgt accaatgact ggtagcaacg gtttccaatc
     4621 ttacgtattg atctcttgct tgttgcttgg ggcaggcgca atttctgcag ttgtttactt
     4681 taagaagaaa gcctagaagg atcagctaat gattatcaga caccctaaga aaaagcgaat
     4741 catgggtaaa tggatcattg ctttctggtt actttcagct gttggtgtct tacttttgat
     4801 gcctgctgaa gcgagcgtgg cgaaatacca acaaaatcag cagattgccg caatcgatcg
     4861 aacaggaacg gcagcagaaa cggattcttc tttggatgtt gctaagattg agttaggcga
     4921 tcctgttggt attcttacaa ttccaagtat ttctttaaaa ctaccaattt atgacggaac
     4981 ttccgacaaa attttagaga atggtgtagg gattacggaa ggaactggcg atattacagg
     5041 aggaaacggt aaaaatcctt taatcgcagg gcacagtgga ctttataaag ataatctttt
     5101 cgatgatttg ccttcagtta aaaagggaga aaagttttat atcaaagttg atggtgagca
     5161 gcacgcttat caaatcgatc ggattgagga agtgcaaaaa gacgaactac aaagaaactt
     5221 tgtcacttac ttagaaccaa atcccaatga agatcgagta acgctaatga catgtacgcc
     5281 taaggggatc aacacacacc gtttcctagt gtatgggaag cgagtaacct ttacaaaatc
     5341 agaattaaaa gatgaagaaa ataagaaaca aaaattatct tggaaatggc ttttaggaag
     5401 tactgttttt ctttcagtca tgatcattgg ttcgctattt gtttataaaa agaaaaaata
     5461 aaggagggta accaacatga gaaatagaaa atggctattt gtttgtgcag ccgctctttt
     5521 ttctttcact gcctacacac agttgacgtt tgcagacaga caagaaagca cggatagcac
     5581 agaacaaaca atccaaacgt cagatagcag cacgattcaa agcagcgatg aaaccgtcga
     5641 ttcgtcaaca gttgattctt cagaagaacc taaaattgct gaagacgatc aaatagtcaa
     5701 acagaccatt cacgttcaaa aaattatttc ttccgaacaa ttagacaacc aggggcaaaa
     5761 gcttgaaaaa caagaaggag taaatggcgc gaagttttct gtttatgatg tatcggacat
     5821 tttacaaaag atggatgtta aggatctcac tactgaccaa attgaatccc aattaaaaga
     5881 tcgagtgaaa aaactatcca gtgatcaact gaagctaatt tctaatggag aaacaaagac
     5941 aattgatcaa caaacaggtg tctttgaatt ctcggtagaa gtacaggcaa atcagaaaca
     6001 agcttattat attgtcaatg aatcaagtcc tgaaaacatt tctaatagcg aggatatttt
     6061 gctattaaca cctgtttctg ataaaaatgg tgaattctta aaggatgtgt ggatttatcc
     6121 taaatcagaa gcttcgcaac ctaaagaaga agtaaaaaaa atcgtatcta ctggcgtaaa
     6181 gaaaaacttc tttgagaatt gttgggattt tgttactcac ttgttttcta gagattaagg
     6241 aagaaataaa atgaaactga tcaaattatt attattcaat ttttcttgtt taaccgcagt
     6301 ctttttgtac tgcggtttat tattttctaa actatctatt ttgccaagct accaactata
     6361 cctaatgagg attttaaaca taccagctgc ttccatgccg ctagatatta tggaaaagct
     6421 cattaggaat ccattattta ctacgatcaa tttgatcgtt attgtcggaa tttcactagt
     6481 catttataaa aaagagggga tgaagggatg aattttaaac actcgtggac aagacggtta
     6541 aaatatgttt ttcccataat gatgatgtta ggtacattgt ttgggttaaa aacagccaat
     6601 gtctttgctg aaaaagttat tgtcgatccg tcaaatccaa tccagaacgt aaagaataat
     6661 tttattattc caaaagatgt tcctaatgca aaaacaaata ttactgtaaa cggagcgtca
     6721 aaagtttaca aatatcatgt tgatgccaac aaaggtggtt ttacagacga ctacgtagga
     6781 ttagtggagg gaaacaaaaa tatacgctat ccttctttcc aaaaagaata cggtgaaaca
     6841 aaccttgttt tagaaggcgt aacaaccaac accaaagtca atattgacta tggaaaaatc
     6901 ggtacgtata acgggaaaaa agtcaatatc aagctagttc tatctaatat tcacttatac
     6961 tcggatacgt tgccgtggaa tctactagat aacaactata caaaaactca ttttcgagac
     7021 gatggctata aaaatacgaa tggtgcaatg agtaaatcta aaaaaagaac agtactttgg
     7081 atctcagaca atcttttctc aggaattgtt taccattcaa cacaaatgaa tgtgcagcta
     7141 gtagccacat atgaggacgg tagccccgtt caattttcag gagatacatt tatcagtttt
     7201 aactctttga accctgcagg aggaaaaagc acggatctta aaggagaata tgcccactat
     7261 gacaaaatga atacgacaga ttggtatgtc agaaaagata cggttctttc agaatttaaa
     7321 tctttctaca acaatctgaa cgtggtaggt ggccacccag gaggaagctc taagctgaca
     7381 caagcggata atgatttcaa taatttgcat gataaattag gagatccgaa gtttggtcaa
     7441 ggtactgtgt cctttaaaat atctgaagca aatccgacgt ttgtgattgg ttcttctaat
     7501 gttcaaacct ggtttacttt atcttctgcg acaatcttta gtgttgttcc tgatcaacct
     7561 gaaaaaacag gggttgataa aaatggaaat aacgtgaacg ataaaatgtt gcaagtagga
     7621 gacacgattc aatatcgaat caaacagaag gtgaatcgat taggagtgga tttactagcg
     7681 gtttacgatc gatttgagtt aatcgataat ttaccaaaag aagtaaatta cgtcgatgca
     7741 cacgttgaaa gtggtacaaa taaaaaattc gatgtatctg gtgaagtgac ctatgacaaa
     7801 acaaaacacc aggtaaaata tgcagcgaaa gctgatacat taaaaaatcg aatgaagtat
     7861 aacggcgaaa cttacgaatt agtgatcaat gtaaaagtca atgaattggc caatcaaaat
     7921 agtgtagcca aaaatcaggg aacgtcgatc attaataaag tagaaaagga tacaaatatc
     7981 attaccgttt atttccctaa aattccagtg aaagaagtac aacaaaatgg aaaagatgta
     8041 aacggacgaa atgacggtaa gaagggtacg ccgacagctc ctttaaacgc aggatctgaa
     8101 gtacaatatc tagtcacaca aaaatggcac acaaaaggcg tagacgctgc gtcagatcac
     8161 tacaaacaat ttagtattca agatccaatt gaagctcgtt tgacatataa agaaggttct
     8221 gcgcaagtaa tagataagag taaaggaaaa gatattactt ctgaaggcac actaacctat
     8281 gatagcaatt caagaacgct gaagtgggaa gcttccgctg acttcttaaa taacaatctt
     8341 ttagatggac gagaaattca gctgatattt acagctaaaa ctccattaca atcagaaaaa
     8401 aatattgata accaagccgt agtagcagta gataatgttt ctaataaaac aaatgttgtg
     8461 acaattgggg ttgatcctaa cttgccacaa gttattgttc ctaaaacagg ttctacacat
     8521 ttagtaacga ttttagcggt cagcttacta ttacttgtgt tagcaacttt tggctacgca
     8581 gttctgaagt tcaattaaac aaaaaaacaa ggctgaaaat cagccttgtt tttctatttg
     8641 aaaatgggat tggcactaat aaatacgttg tctgaagaaa gtgatccgtc tgcagaaact
     8701 tcataagcat gggataaacc aacgatactt tgattgttgt aaagcaagtt tgcgttatga
     8761 gcagcgctat ctttccacat aaccatagca tttactgctc ctgtatctga aaggatctcg
     8821 tcaacgtaaa ggtagaaact attgatattt tctcctttag caccgtagca gcctaagctt
     8881 tctaagagat cttggaaagt accgccgcca ggtcggtaat gactgaagct tacttgtaat
     8941 tcttttgcac gaatatctgc agcttgttga acgatatcat tgaattgcat tggggcaacg
     9001 ccattttgtt gacggtagct atttaaccaa gcaagttctt tttgacgcac atagttgttt
     9061 aaatcactta gtgagatatt tttgtatttg aaagtgatcg ttcgattttg gtcaacatta
     9121 ttgattacac gttgtccatt tttatcaacg gtaacagatg aatcgtcatt tctacacaag
     9181 aagtagtttt gatcggtcat atttttccaa gaagtagaga aactatctcc ctcgtaaacc
     9241 gtttgtgttt cagtagataa aacagcgttt gtgtcaacgt ttatatggtt cacagtgacg
     9301 ttgtattgat gagtataggc aaaattgatt ccttgattac ttgtaacgtt gtttaaagtc
     9361 acagtgttgc tagagctttc tctaggatca agaacaaaat tagtgaacat aggtgcttca
     9421 attgtgatgc tttgtccata aacgacggga taactcttac tgtaattata gagttcttgg
     9481 atatttggat cagtatccga gactttattt ggacgagctt tcacttcaac tagaaagact
     9541 tcatcatagt aaaaagtaaa tgtggtattt gtgttaatcg tttgtgtttg tgtttcattc
     9601 ccatttactt gatactgtgg tgcttcaaag ttagtcaagt cggttctagc ttttgcagtg
     9661 taacttgtac cagcttttac tgagacatgt tcttctttta gcagcgttcc agtttgtcga
     9721 ttcatatgac ggacagttac cgcatattct gaaggtttag gtttgtgttg taacccttta
     9781 aatgcagaat caagactatt tttagcatta tttacttggg tttgagaagc tttagaatcg
     9841 tctagtactt ttttagcatt ggataaagca gtctgaaaat tattccaaga tccttctgta
     9901 aaatctcctt tagcagttga ttttacttgg ttgtacaagg cttgtaattc cgttttgttc
     9961 acagtaggag ctggtttttt ctttaatccc ttgtaagcag aatctaatgt gtttttggca
    10021 ctatccactt gtttttgagt cgcttttgag tcatttaaca cttttttagc attgtttaaa
    10081 gcggtttgga atgcgttcca ggtattgtcg gtatagtcac cttttttagt tcccttaacg
    10141 ctcgtataaa gagcttctaa agctgattta ttcactttgg gtttagaggt gtcagcacca
    10201 taccaaccaa taccttcgta tttccagcca tagtctttgg ttaaccattg tacttctttc
    10261 caacttgcag tgtagtgatg cgaaccagag gtaacacctg gaaggaaaag gcggtagatc
    10321 ggtttattat ttttttcggc agaacgccag gcaggccctt cataagtcca accgtaattt
    10381 ttggtcaacc atttcacttc atcccaacta gctgtgtaat ggtgatcacg aaggccttta
    10441 ttgtataaac gatagacaag gtggccaccg ctagtcggtg cttcccaagc ggggccttca
    10501 taattacccc acttaatttt cactaggtga tcacgttctt ttgtgctaga ggtgtaaaaa
    10561 tgttcatggt tatttggatt ataaaggcga tacatgacgt tagttgaagc agcgtcagca
    10621 gatccagcaa gagcaactgt ggcagcaaat gttccaatag ctataacagt ttttgggttt
    10681 aataatttca tgttttcaac tccctattaa atgattaaat tcggcgtatt tggttagttt
    10741 ggcagcatta tcaaatcgca ttttttcaat cgcacttttt ttctttatta aatccgcaat
    10801 tgttgattct gcgactgaag aatgtttgct aatttcatat gctgtcttgc cagtttcaaa
    10861 tagtaaccat tcgattttct ctttatcagc gtacattgca atgctccctc ttgatttttt
    10921 ctttattata gctctttttt gtaataaatc acaatatcaa gaggaaaagt ttctatagaa
    10981 aggtgggaaa ttatgagtat ccgttccccg tgtatcaaaa tgaggtttgt tgctactttc
    11041 gttatttaat atactaaaat aaaacaacga aagaaggaat agaatgaaaa agttaataat
    11101 ggtatttact tcgttgattg ccatgattgt tattttaggt ggatgtggta gtgaaaaaaa
    11161 taagcaagat agtcaagata atggcgtgtt aaaaccagga acagtgtgga aagaagaagt
    11221 aggcggactt gttcataatt taaaaattat agatgataca acatgggaat attccgaaag
    11281 tgtttggcat cctgaacaag tacaaataac agttgagaag ctaaaagact ataaaggatt
    11341 agaaagatat aaggtaatcg attcaggtgg agtagattta ttcataggta aaacagcctt
    11401 aatagtttcc tataacaaag acggtttaga aacgtttaaa tttattccaa caaacgaaaa
    11461 agaacatcga gataaaagtg aaatattaaa agaatacagt actaaatctg gatacaagtt
    11521 acaaaagact agcgagtgat tgctagtctt tttatttatc ctgaaggagg aatcgcagtg
    11581 gcaaaagcta aaacgccatt tgaaaaagcc gcgtctaaaa tcttagaacg tcgcggtgta
    11641 tctgaaacac agtggaaaca agaagtcctt gaaaaagcac aatttgacct attacgggga
    11701 aaagacaagg acttagaagg atatatctat caacgtgaac gtgaaaagct tgttttcgat
    11761 gaaattatta aacactaaaa ggagcgaaca attttatgtt tgaatcaatt acaatgaatt
    11821 ttttaacaca accgaaagta gtagctgcgg ttgatatttt tagagcatta caaggtgcag
    11881 caactagttt aaaaaacaat ctgatgattt ttgcggctgt agctgccgtt gcctccattg
    11941 ttcttggggg gattttcttc ttctttggcc gaagaggagc tgaaaacggg aagatgcacg
    12001 taggttatgt attgatgggg gtaggagtta tattagctgc cgcctctatt gtggtttcgt
    12061 tatttggaat gtttggacaa accccacagg gactataaaa aataaataga aggagtaaaa
    12121 agtacgtggc tactttttac tcctttttta tgaaaggaga atactcatgt actttacgat
    12181 ttcaggcaat accaaaaaag ataaagagtt aataaaaaaa gcaacgaaga aagtgggaaa
    12241 gcgtactgcc tttttaccga aaacaattaa atattctgtc attgaaacgg aagaacagct
    12301 acatgtgtta ggacaagtgt tagaacaaga gaatcaatct tctgttaaat tgactctcac
    12361 gttacatgat aaagaaggaa aaatagaaaa ggctggcaca gaatacgttt ttggcccact
    12421 ggattatcaa atttcagaag gtttttatcc tacattgatg gatttgatcc gccttgatgt
    12481 gtttaaggaa acggatgaaa ccatgagtgt ggaagagtct tatcgaaacg aaaaactgct
    12541 acaagtttta gaagaagagt tagagagcga ccaaagaaaa gtgagtcaag tgagtgaagt
    12601 cgaagtaaat gatgaagtac catgggaacg accaatcttt ccaaagaagg agtcaaaaga
    12661 aaaagagaca gtctatgttg acgaacaagc tgatattccg actcagaaat cgatatttga
    12721 ggaagagaac gatgtaatgg gtcaattgga ggtagatccc tttgaagaaa caatggagga
    12781 tgaagagacg gccgaagtag aagttgatct agttgaagct aatgaagagc caacatggac
    12841 tgaaggggat tctcaggaat atattgaacc acttatcagt gaagaagtag agaaaaacga
    12901 aacagagata caaaaggcaa ctgtatttga ttatattttg gatcaatatc cgccagagca
    12961 tgaatggatg aaagaaaaaa ataaattatt tttaaatgag ctttattcga aatatcaatt
    13021 accccaaacc tatcaagcat ttttagagag taaagaagaa ttaatctcac agggtaaagg
    13081 cacactttta gaacagttag agtctgttca atcaacaaat tggcatgagc ttgcacaaga
    13141 agatttatta gccacttttg aagaacgtca acaagaaaca gatcaagaaa taaatgagta
    13201 tgcgacggaa cagtcatcta attgggagag aacaaaagag gaactaaata aagaagaaca
    13261 acgagtgatt gaagaagaag tacaaaaaat taaagagcga tacgaaaaga aacgcgacaa
    13321 tgcgtattcc ttgtgtatag agaaaattaa taactttact aaaactaatc aagaagcttt
    13381 atcgaaagaa aaagaaaact tgttaaaaga acgtataaaa gaacgaaaag aagagttcta
    13441 ccgaggttta cgtacagata agctaaagat tagcaaagaa ttaaatgaac aactgaataa
    13501 actttatcaa acaacgactg aagttcttat ggaaagacac gggcagatcc agcaagaatt
    13561 acaagcacaa attccaaaat ggaaaaaaga gtatgaaatt caacaacaag aattgaaaga
    13621 acaagaagaa aaacaacgac aagaagaaaa agagcgcgaa caattagaac taaaaaaacg
    13681 tgagcagcat cttgcagaac aaaaagtggc gatagaaaaa caacggttag agcaagaaaa
    13741 ggaaaaagaa gcagctgctc gtaaggaacg tcaagaacaa atggatacat tgcgacaagc
    13801 acagttgaat tatctagcac aacctcaacc agtagctgct gttcaaacgc cagtgaacaa
    13861 ccaagcaaat ttaactcctt caccacagcg ttcctttaac ggatggatgg tgggatgtat
    13921 tgcaagttta agcttgcttc taggtggagg aacagtattt gcttttaatc atatcaatca
    13981 atcttcacag gcagattctg tagccacaac ggcgtcaatc aaggaagaag cccaggaaca
    14041 agcaagaaaa gagtatgaac aacaattgga agaattattg aatcgtacca atcagtcaac
    14101 agcagagtca agtatggaaa atagcaaaga gagtgatcct agtaaggcta aagaaggatc
    14161 aagcgattca actgtacact caaacacttc cgaaagttca gaatcaaatg aggtgaaata
    14221 atgcgtatta gagaaacaac gagacgaaaa gacaaacgat tcaatttaga aaagaatagg
    14281 tatctttctc atttctatcg ctatactcct tcaggagaag agctaccaga aaaacatgac
    14341 aaacgtattt ctcaaaagat tttttatagt ggcttagctt atcttccttt aaactatgtt
    14401 gttacaagaa taccagaagc atttcatcga tttgagatta ttccaggaag tttacaagga
    14461 gtgaatattt ttcagttaca agaaatgccg cagttattcc attttgattc aactggtttt
    14521 tggaatcctt tgaccccaac aacaagttta ggcacacgtt tagttgtttc tacgatttgt
    14581 gttgttccag ctgtacttat gggattgaaa atggacatgt ggtttcgtcc gctagcagat
    14641 gggcaaaaag gagataaccg attaaaaacg ttaaaggaaa tccaacaaat ttatccgcaa
    14701 ataccagaat caaagggaag ttttcctggt tatggcggaa taccaattac tcattataaa
    14761 aaatactggt atattcagac ggatacagta aatacttgta ttgttggtac ttcccgctca
    14821 gggaaaggcc agatagaagt tttagcaacc attgacaatt tgtcgcgtgc agaaagacaa
    14881 agttcaatgg ttgttaatga tccaaaaaca gaattatatg ttgctagtaa agatgaacta
    14941 gaagctagag ggtatgatgt gtatgccttt aatatcaccg atccactgca atcaatgagt
    15001 gataatccat tggcactcat tgtgaaatac tggaagcgag gagacataga caccgcaaca
    15061 cagttaacca atacttttac gaatacgatt tattatgatg caaatgcttc agacaataaa
    15121 tactttaacg aaaatgcgca gaaagctgtc aatgcgctta tttttgcgtt attggaacaa
    15181 gcggatcaaa caggggatta ctccaaatta acaccaaata atctcgttga actactttca
    15241 gaaattggcg gttttaatta ttatccagat cctgagaatg aattcaagca gctcaatgcc
    15301 ttagatgagt tcatgaatca gttaccccct ggaaatatag caaaaaaaca atatggggca
    15361 acaaaaattg gatctgataa agcgaaaggg aatatcttgt ctacggcaat tacaggattg
    15421 aatccattta ccctaacgaa aattgcgaag atgacttctc aatcgaccat tgattacaag
    15481 tccattggtt ttccgaagta tttggatctc aaattacatg aaagcctatt aaatcaacgc
    15541 attgtcgtgg aattttatca taagggaaag aaatttcacg aggaacgagt caaagttggc
    15601 tatcgtggtt tttgtgaaat caactttgat tgtcatttag agcagggaga tcatgtttgc
    15661 ttaaaataca atcatcaagg aaaacaatat gttgcttggt atgagttttc tcaaaaagta
    15721 ttgaaagacg aagagggaaa aatcgtttat cgaaaaaaac gaggagaaac tcatttgcca
    15781 gaactagaaa aagaagccgt tctaacatta gatgagaaga aaagtaacct attagtagag
    15841 tctattcgga tgcactatac cgataaacca atggctattt ttatgttaac gcctgattat
    15901 gatccatcta accatatcat tgttagcatc tttcttagtc agttgtataa agaattatct
    15961 acgcaatgtg ttaagactaa aggagataaa tgtcaccgta ggattcattt tattttagat
    16021 gaatttggaa atatgccacc gatggacaac atggaaggaa tcatgacggt tacggcaggt
    16081 cgtaatatgt tatgggatct gtttattcaa tcttatcagc aactttatgc gaagtatgga
    16141 gaacaaaacg cagcgattat caaagaaaat tgtcagacac atatttatat tatgtcgaca
    16201 gatgataata ccatcgaaga attttctaaa aaagtgggga ataagacggt tgaacaagag
    16261 aacagtacca tcaattcatt aggtatgaat actcatatca atcgcaatgt tgattcagat
    16321 cgtatcttaa ctcctgaaag aatttctact tttttagaag gtgaaacgat tgtactcgct
    16381 cctttaaaac gacaagattt gaaaggtcat aaaatacggc cgtatcctat ttttaatcat
    16441 ggggaaacga atcttcctta tgcttatcaa tatattgaag atttcaatcc atcgtgggat
    16501 atcaatgata tagacataca ttgtacacat gcggacttgg atcttaaggc tttacaaatt
    16561 gattatgatt atttcctacc agatgaatat gctagaaatc tctatcatgg actgcatgat
    16621 caattagaag aaaaaaacga agaaaatatg ttttataaaa tcgttcaatc ttttgagaat
    16681 gagacggcta aaaaattgtt aattcaattt tacgaagaac aagcaacgga tcgtcttcaa
    16741 gaatatgttg aaaagttgat caaaaatgaa gaaatttctg aaatgattag gaaacggctg
    16801 ttattggaag ctgaaaaggc ggtgaaagaa tgatcattgg aggaattttc tctggcatag
    16861 ccgactggtg gtcaggttta ttcggagaag gggatgcaga tcccaaaacc gtaacgaaag
    16921 tcttacaaga ttatggtaat tatctgcagt atcaagatgt attcagttgg atttgtaata
    16981 cttttttatg gggattgatc aaagggttat ataatctcaa tactttatta gaaaaaacaa
    17041 tttatcaaag ctttgattta aaagacttat tgaacgccgc tggtgttaat gaactatttc
    17101 aaagtttgat tagtaaggta ttggctcttt tttgtgtcgt cacattaatt tatttaggct
    17161 tgaaattttt tatgagtaaa cacccaccga aagtcaaaaa tatcttggtt aatttattta
    17221 tggccatgat cttgattttt ggtggtagtt ctttaatcga tgaagggtta aatatcagta
    17281 aaaactttta tggagacgtc actgcagcaa ataaagcaga taaaacgggt tcacctgctt
    17341 ttcaaattat tcaaaataat gtgattgatg tcagtacatt actagcgact gacccgaata
    17401 aagtagaatc cttaccaaca gataaaagaa atgctttaac agcgaaaaat ttcaaaacag
    17461 cgaatatcaa tgggattatt acacctgatc aagctaagaa aatgtctgaa tcaagtgata
    17521 ttagtacagt acaaaaagat cggttaaagg cattacagta tcgactagag ttagacgata
    17581 atgggaaaga aatccctgtt caaattagtg atgaaggttt agcaaaatat gtgtatacgt
    17641 caggctatcg tcgatacatt agtagtccag ggattatttt ggctggggaa tcttctttgt
    17701 cggtagccta tttatttatt ttgtttacaa tcgttacttg cattattgag ctagtattta
    17761 aaaaattcta tttagtaatt gccgcgtcaa cggactttga gacaggacaa cggatgaaaa
    17821 gtgcgataga agatatttct caatccttct tgttattggc gtttacgatt ttagaattac
    17881 gaatctatac attaatgctt tcaggtatcg gtgatttgca tgcggtagga aagatcaatg
    17941 gattcttgta tgttgttgct ttaattgtgc taactattgc gctattcaaa ggctctcaat
    18001 cggttacgaa gattttcggt gttgatacga gtctgaaaaa cggcagcaat tctcttctta
    18061 gcatgtttgc cttaggaaat attgcgaaaa atgtgggtag cggagctaaa aaccttgcaa
    18121 gtgctggtaa gagtggttta agccatttaa atgatattcg taagaatgga tttggccatc
    18181 gaaaagatat tacccatgat aacggggaag aacaatcaga cgataaagct acaactgtac
    18241 ctaatagtaa gaagacagtt tccgaaatgt tcgggaaagc gaaaaatggt gtttctaaag
    18301 ccgcagaagg tcttggttac gtcaatgaac gtgggttaaa aggaacagtt gaagatctta
    18361 cagaaaaagc caaagacacc ttagaagaga aattagacgg cacgagagct aaagaatttg
    18421 ctgaagctgt gaagaatcca tccgaagcac tagaaaaaca aaaagaaaaa gcttcagcag
    18481 tcaaagaagg actaaaagat gcgtatggtg aaggacaagt caatgcagca gtgaaggcaa
    18541 atacaacaag tgaaaaagaa aatcaagaag gtgcagcgat tccttcagcc aaagatcacc
    18601 aagatgagtt acattctaac gaaaattcga tcggagaaaa agattcagaa gaaggacaac
    18661 atggtcagtt accaaaaacc gatccagaac aatatcgtta taaatctaac attaattctg
    18721 aaaacgaaaa acgcatttca gatttaccaa aacgaaatca agaagtacaa acggatgagg
    18781 attccatcga tctgccaaat gataatggca tcgaagttgg aactgaaaaa tcaacgaaaa
    18841 ttggtttgcc taagacacaa aatttaccaa tgaaagatag tcgtttgaat caattcaaag
    18901 agaatgatca aagctttgtt catcaatcac ctgcaggtac tgttcaaatg aaatcaagtc
    18961 gtttgcctga aaatggaaat ctgacaactg tttcttacaa tttagctgaa agtggtgaaa
    19021 cagagaatgc gtccgttcaa aatattgtga caaaagaagc tgcacctaag ccaatcaata
    19081 aagttcataa tggatacaga ccagcaaacg tagcatttac tgcaccgaca aaaataaatg
    19141 tgacaagaga aactaaaaac aggaacaatg aattgaaaga acaactattg aaggatatca
    19201 aaccataaaa ggcctattta agggcctttt tctttataaa acaagtttaa aatggaaagg
    19261 agaaaattgt ggaggatatt ttaatagcta cgtttataac tgcactggga gcatttttaa
    19321 cgatatttgt ggtgactatt aaaggattta aagatacgga tagtttacaa aaagatcatc
    19381 agtctatttt agatggtcaa aaaacacata ccgaaagcat tattgtacac ctttcagaag
    19441 gattcactta tttgaaagat gctatgccca cattcacagt aaaattaacg gaaatatttc
    19501 attctgttga gcaaatatcg tcagaattga aagagcaaag acaacaaaaa gatcgtcaac
    19561 ttggctcact taattttagg caagaaacga tacaagaatc attggagaat gtaaatcgat
    19621 taaacgatga aatgcaacga gttcatttgg aaaatgaaga attacgcgca caaaattatg
    19681 atttaattca aaagaaaaga aatctggaac aaaaaattgt tgaattaaaa gaagaaaatc
    19741 gtcaattgaa ttatcaatta cgacgaggaa aaaatcgttc tcgtgattta ggaaatgaat
    19801 tagagttgta atatttagaa aaacgctgtg agaaatcaca gtgtttttta tttctaaaaa
    19861 tacaaaatat aaggggtatg gttatattat ggataaatac attcatatga aaaatcctcc
    19921 aagatttagt ggggaatgga agtttttcgc ctttttcttt ttagatctat taacgcttgg
    19981 tggctgcttt ttttgggcga aaatagtcaa taatcttgtc cacttaccac tcttttttgc
    20041 actcttgaat tatggattat ggcttgcgat agcgttagtg attgtttggc gaccctataa
    20101 taaccctggt caacgccaaa tttttgcgat tatcgaatct attttcttta cggataagaa
    20161 ccactatcat gcgttagatc ctaaccgaaa ttatcatggt acgtataagg aggatgaata
    20221 aatgcgagtc aaaggacaaa attcagttga taagaaatcc attttgcagt ttggaaaacc
    20281 agaagagcgc tctatcttgg acttatttcc atataaatcc tgtacagaag agggagtctt
    20341 aattactaga gaagatcatt ttcagcgtta ttatcgtgtc gtttccactg acgtggaggg
    20401 attaaatgaa caagagaaac tagaacgaat gaatcagttg accaccgtca tgcgtacgta
    20461 tgtgccaaca attaagttag ttagtttgac cacagagacg gatctaacgg aacaaatcgt
    20521 gcaaaagcgg cagttattag ataaaaatcg tatggaacag tcactaggaa gaaatctaca
    20581 gcgattaaga aaatatgaaa agaaattagt agaggagatc caggaattaa aacgggcaga
    20641 acaagaacgt cctgacttaa gcttcttttt cgttattgaa ggaaagacaa tcaaggattt
    20701 acaaactaga aatcgtcagt taatgcgatc tagtggcatt ttagggttaa aaccactcta
    20761 caaaaaagaa ttgattaaga ttctttatcg aatgaacaac atgaatgacg aataaaaaag
    20821 atggaggaaa tgattcatgc tagatgtgat aaaaacagct ttttcaacgc aaagtaatca
    20881 aaaggtgatt gatccattaa aacaacttgg taatcgtgaa atagagattt taaaatcaaa
    20941 aggttatgat ttagatttct taaaacaagt gatgccacaa ggtgggttga attttgatga
    21001 agaatatgtg acctatggaa atggttattc acgatgtgtg acagtttatc attacacaaa
    21061 aaatcctact cttttttggt tggccaatct catgaacaat cctcatacag tggccacact
    21121 agatgttagc acagatgaaa agcaaaaagt gattgatcaa atcaaccgcg cattagatga
    21181 attaaatgat cgatcagata atgaacgaaa agcgactgac cgaaataaaa gtgcggaaga
    21241 atacctggaa ctagcggaat atgcccgaaa attgacttct aatggggaaa tttctaaaca
    21301 agtcaaagtg agagtacatg tttacggaaa tacgatccaa gaagtggatg aacgggcgca
    21361 ggaactgatc gaaaatctaa aagggatgga ttatcgtgcg gtgacttatc tgcataaaac
    21421 caaacgagat tggcaatcga tgtttaccat gttcgatgaa caagctgaat ggtttggaaa
    21481 tatcaaaggg caatcacttc catcgttaaa cattggcgga ggattcccgt tccaccacca
    21541 aacgctaaaa gatccaggag gcacacaata tggggaaacc atgacaggcg gcccatttgt
    21601 ctggaatgcc acgtataaaa atagtgtacg tttatctacc aataccttgc ttctaggaat
    21661 gatgggagct ggtaaatcga ccgttcttaa aatgatcgcg gaagcccatt tagctgcagg
    21721 agactttatt tggggctttg aaaagggaaa agactttatt cctttcttaa aggaatataa
    21781 cggtattatg gtgcgtttag acggatctga cgggatgatc aatcctttag agatctttgc
    21841 cacacggacg tatgatgaag catccagttt atatgacgat ggttcagtca aagatttgaa
    21901 gatcaatgaa gcagcgtcct atcaaacgca cttagacaaa gtagtctatc aggtacagtt
    21961 agtgagtcct cagctaaaag gaacgatgaa agcagaattc aagacctact tgaatcgttt
    22021 ttatgaagag tatggaacag taccacgcgg ttttacttcc tcaaattcgc gttcaaatac
    22081 tgatacgcaa gtcacaggga aagatccaga agcttatccg acgttcaaag aatttttagc
    22141 ctttttagga caactggaac taccaggggc ttcccaagag aaaaagaatc ggaaagaaga
    22201 aatggagtct atcgtggaat ccttatgtga gacttatggc atgatttttg atggtcatag
    22261 tacgattcga caccttgacc aacaacagtt ggtctttttt gacattgact ctattacagg
    22321 cctagatcga ggggtacaac aatgtcagat gtacatggcc atgacgttga tttggaatca
    22381 ggcattgatt caaggacgaa gacaacgacg cttaattaaa gaaaaacaaa tggaagaaca
    22441 agacttcaaa cgcttcttgg cgatgattga tgagtgccat aatgcgatta atccagattt
    22501 cattgaaacg gtaaattatg tcacaaactt ccaacgagaa atgcgtaaag tagaagcaat
    22561 gactgtttta gctacacaat ccccacaaga aatggtgcca gaaaatatgt cttctgataa
    22621 cttctcgaaa ctgaagaaag tctttgaatt ttcttctacg aagatcttta tgcgtatgga
    22681 tgaatctatt ttacgtcata tagaaggatt agttggtaaa tcaatgacga actcagaatt
    22741 agaatccatt cctcaacaaa atcaaggaga cgctgtgatc aattttggct caaaagaaac
    22801 cattcgtgtt cattttagtc cgaacaaacg tcaattaaaa ttgtttgatg gaggaaaata
    22861 atggaaaacc aaaatgaaag tttaatcaaa cagtatgtta agcgtcgtgc aaagcggcgc
    22921 ttatttttgt gggtgtttgg tacttctgca ggtttgatta ctatattgat cactgtgttt
    22981 gtgacccttt ttctaatact tgcggcaggt tctattgata attctgattc aagtagtggt
    23041 ggcgaagctt ttacaggaga atattcggaa ggcttaccca tttataaaga aatcaaagga
    23101 agaggccctt tttctgatga gattgcgcaa tatgctgtag gtgcagcagt gaagtataaa
    23161 ttattaccaa gtgtgatcct ttcgcaatac ggttatgaat cagcgtttgg tacgtcggcg
    23221 tccgcaagaa atgatctcaa ttattttggg attacgtggt ttgatgggtg tctgtttcct
    23281 aaaggaactg cgcgtggaat tggtggcatt gaaggtggct ggtacatgaa gtttcccaac
    23341 tcaaaagctg ccttctccta ttacggcttt atggtagcca cacaatcaaa ttttaatgct
    23401 tgtgtcggaa ataaaagccc tggcgcaagc ttattgatct taggacgagg agggtatgcc
    23461 gccgcaggaa ttactgaaga cagtgcctat tataaaaatt gtatgtctat tattaataca
    23521 aataaattga tggagtacga tgagtttgcg attaaacact ggagagaagg cggcggaact
    23581 ggtggtacga ttacaggaag ctggggcaat ccattcccag gaagtagctt agataaaaat
    23641 tcgttcagtg gaggacaact ttttgggaaa aatccaggag gagaattccg acctaacggg
    23701 ttccatgatg gactagactt tggttcagtc gatcatccag gaagtgagat tcatgcggtt
    23761 catggcggaa aagtcgtgta cgttggcaat cctggtattt caggtttggg tgcgtgtgtg
    23821 atcgtgatta attacgatgg cttgaatatg gtgtatcaag aatttgcaaa tagtacagga
    23881 aattctcgag tgaaagtagg cgatcaagtg aaagttggtc aagtaattgg gatacgagat
    23941 acagcacact tgcatttagg atttactcga atggattggc gtcaagcaca aggacatgca
    24001 ttcattgatg atggtacatg gatcgatccg ttaccatttt tgaatagcag caaaaaatag
    24061 atcaggagaa aaaatatgga aaataaaacc ttaaaaatcg tcttaacagc tgcaattagc
    24121 gttagtttaa tcggcaatat tgcgttgttt tggcagctta aagaagaaca agagacaaat
    24181 acctataaaa ttgaagaagt ggctaaaaac gcgtctgata agctcaaaaa aaattcttct
    24241 gaagcacagg cgaagattga caagttaaat caaaccatca atgagaaaaa ccaagaaatc
    24301 gatcagctga agcaacaaga tggcacaaaa gcaaaagagg aagtaactga agcacaaaga
    24361 aagacggcag aagagttcgg tcaattggcc attgataaat cattaagcag aaatgaatta
    24421 acggaaaaac taaaagatgt cgcaacccaa gaagtgatcg acaaattaag tcctgtagac
    24481 gatgatcacc aacatgatga ttacggaagt tactctttta cattaggtga cgtgcaaact
    24541 tacgctcaaa caagcagtgt aaaagaggaa caaaattttg tcgtatttgt tgattataca
    24601 atcggcaatc ctcaattcaa agatgtcaaa ccacaaaaaa taaaaggtgg attaactgtc
    24661 actgaaaaac aagtagatgg tcaatggaaa gtcacagact ttagttattt cactcgttag
    24721 gaggaagaaa atgagtaaga aaaaaggagc aagacaacgt tttaaaaaac gaaaaagtta
    24781 tcttagatgg ctggggatct ttatgattct cggctttttg attcttgcta gtccgattta
    24841 cacacataaa aaggtagaca taccagatga agtaagcacg aacgcatttt taaacacgaa
    24901 ggaactgacg atggtttcaa aagaaaaagg agcgaaccag caattagttt ttgaatttgc
    24961 gatcgacgat gaagatcaga gcttattaaa agaactagct aatcttaatt atcgtgtaga
    25021 agtaaagaca gctaaagggg attatcaagc aataaaagcc aaagtgatca aggtgtctga
    25081 tgattatttt gtagtgaagt tagcacatgt accagaagaa tatattgcta tgcgattaac
    25141 tattattcct gaaaaaattg atccaaaggt ggatatgcaa gaaccgcaag atctgatttt
    25201 ttatattcac gaagataagg tcaaagatca cgtgaaagac gaagattatg aacaacatgc
    25261 gatcaattac aaagtgaaag gatacaagaa agaacaaaaa gcagcacaaa aacaaattga
    25321 atccttccaa gcaaccattg atttgaatga agaattagtg aagaaactaa aagatcaatt
    25381 gccttatcaa gtcgcagaag atcaggaaaa tactgaaaat aagattaata gttaccagca
    25441 agaaattgaa acatcgaaaa cgcaaatgaa agatcaagaa gagagcattc aaaaacttca
    25501 agaaaaaatt gatcgtatga caaaagaaaa tatttagaag aataggtgga gtaaaagaaa
    25561 tgaagcgagc gaacttggtc ggcaaagata ctttcgctga gcagaaagta ttgattaaag
    25621 cctatctcaa agttgtaaaa gctaaagaaa tatgtcaaga agtgaattat ctaacacaac
    25681 aatatctgag ttgaagaatg gtagaaagag tttagatacc ttaaaattca gatcatttga
    25741 agctctatat atagctgcta aaaaatattt tacagctgat aataaataaa aaattaaggt
    25801 gggttctatg tgaaaaaaac gtatcaaaag tttttatgga ttagctatat cgtcctattt
    25861 atcgttgggt ttctcgtcag tgtgtccgtg atcgtcggaa cgctttttct tttgttctct
    25921 gacgaagatc tggtacttaa ggggttaatg agtacgttat cgtgtgtcat gttactttat
    25981 ttatgtatac agatcaacga aattatgccc cctcattggc aagaaaagaa gaaagaattt
    26041 aaggaagaaa tcgaaataaa atccaatgac tggattgaat acacatggct tcctctgaaa
    26101 agaaatagca aacgaaagga attttgggca ttgcaattat ggccaatagg aaaacttttt
    26161 atttatatgg cttcacttat ggttacttta atcggttatt tggtggtggt ctatggggtg
    26221 gcctattact tgttaagtga gccaaaacag atcgcggcgt caaatatttt cacggcagta
    26281 atgacattaa tgtgtgtcat gtgcttttct atttttagtt acttactcgt ccaatttatc
    26341 aggcaaaatt taacaatgag taaacttttc aaaagtttat tggacttact tatcttaggc
    26401 agtatgttaa cgactctaac agatcggttc gaacaatctg aaaaaacggt agaggggata
    26461 aagaacttct taacgacgat tgatcaattt ataaatggat atatgtattt gtttgaagta
    26521 ggctttattc tcactttgtt tggttgtgta tttataaaac tcattaaaag atcaatcgaa
    26581 aaagaaatgg ttattgatct aattccgacg ctgagcggct atgagtatta cgttgatttt
    26641 ggaaagtatg aggagttgat ccatacggat atcgttcaca cgagtatcca tgaagtaacc
    26701 gttaagggca tcagatctac tttaaaagat ggacaggaga cgaaaacaat cgaccgaaga
    26761 aaagaggtct acaattttta taaagttgaa gcaagtctac gatatggcat tgggaaattg
    26821 aggttagatg ggagtaatat tcaacaaaac aaaccatatg ttttaggaaa agtggtgatt
    26881 tagaacttcc tatgaaagat gaataaataa ggagaatctt ttgaaaatga ttcttcttta
    26941 cagaattgtg cttatagttg gcacggagtt aaaaatctta aagaaggagc agttattcaa
    27001 agtgaaagaa catcataatc agttactatg tattaaaacg ggtacgatga acattcaata
    27061 ccgaacagaa tatttagaat taacgaatca aactgatttt ttgtcgattc gagagcaaca
    27121 taagcaagaa aaattaatgg ctacttatag ccaattgatt gatgagtggg aacaattcaa
    27181 ggaatctaaa acataaaatt ccatttaaac accttatttt ttaaagagca taaggaaacg
    27241 tgtacccact ttcaaaataa agtgggtaga taggctgtgc ctatcacgtt tctgaaaaaa
    27301 ataaatgacc ccaaaatttt caatttatgt gtaggtttat gggtagcaaa aatatgaatg
    27361 tgggcagcaa aaagttcatt tgtgggtagt aaaattcaaa tgtgtgtagc aatgtgtgta
    27421 gctacacaca ttgctacaca cgctataaca tatagtgaaa aggagatatt tatggaagta
    27481 aaaataagag atattgatga aaaaacgatt caaagaattg accgaagatg tattgaatta
    27541 agtgaacgca ccgggactaa atggagccga aatcgatacc taaaagtttt gattgaaaat
    27601 gattttgacc atgaacttat ggatcataga aaagatcaat ttgatcggtt gttagaaaaa
    27661 tttgtggata ttcaaactta taatacgaaa attttagaag aatatattgc aacaaataat
    27721 caattaatcg ccttgttaat tgaataataa aaatagtatt gtgaatttat aaaaggagga
    27781 aatcaatttt ggcaaaagca acaagaaaac atgtatatct ttacgatatg catatcgaag
    27841 tacttgatga aataatttct actcatgaag atatatctaa ttatagtgaa gcagtcagac
    27901 atttgtgtat gatgtatgat ccaaaaatcg aagaaaaaat aaatccaatt caaattaaat
    27961 tgaatgcaat gggaaaagaa atttctatat taaccgaaat ggtttcagag tttgcggatc
    28021 ttcatttgaa agatacagga atactaattg gtacaaattc aactgtctat caagaagcaa
    28081 aagagcgtgt ggaagggaaa ataaaagcga atcaaacgaa aaagtattct cctaagatca
    28141 agaaaccaat aaatgaatct gttcatgcca gagtagaccc gtttgatcca acaaagtttt
    28201 taaaaagata aaaagtagaa ggggaacatg atgaataaat cgcctgcagt cattctcact
    28261 tgtcaattta ccttgcccaa taaaaaatct ttttcaacat acattgatta tatgacaaga
    28321 gaaaaagcgc tggaagaaaa ggaacgacgc acgccggacg aagaacagga actgcaacga
    28381 atcaagaatg ctttagagga tttttatatt cctgaaggag aaactttttc ggagagtaag
    28441 acagataaag aattcagtga aacgtcgaat gaagctcaat cgttgatgga acatggaatc
    28501 aattttgaca agttagagga acaagatttt accaaatatc tttcttatat gacccgtcac
    28561 tatgcgttag aacaaaagaa agaactgacg caaagggaac aaaaagaata ccaacggttg
    28621 aaccaagcaa tgaaaaaata tcaaacagag ccacataaaa aagcttcagg aaatcttcct
    28681 ggagtttttt ctatggcttc agacgaagtg aaaggaagtg atctgaagga gatcaaacaa
    28741 atcttccaaa gagggcaaca aaaaggctca atcatttatc aagatgttgt ctctcacgac
    28801 aattcgtatc ttgaaaaaat gggcttgtac gatcccaaaa cagatacctt agatgaagaa
    28861 ggattaaaag cagctggaag aaaaatgatg gagacattat tcgagaaaga acaattgaat
    28921 gaaacaggtt actggatggc aacgattcac cgtaacacta agcatatcca tattcatttt
    28981 gcagttgttg aaaaagaaaa tacgcgtaaa ccttacacgg aggttgaaaa tggtgtgagt
    29041 tatatcgtac cgaaaggtaa gagaagacaa gcaacattag acgcaatgaa gaccaattat
    29101 gtacatgagt tagaacgttt ttcttatgaa aaggatcgaa tgattggtat ggagaaacga
    29161 aatttattga cgcggaaaag tgatttgcgt aacaccttaa caaaagtggt aaaagagcca
    29221 gcgcgttacg atcgacacgc aatgaactta ttaaatgaag tatataaaac cctacctgac
    29281 aaacgttcgg aatggcatta tggggatgaa aaacgaacca aactttcacc atacacaaga
    29341 gagaaactcg atgagttaac caaatatgtg ttaacaaaag aacctgaata tcaagaatat
    29401 atacagattt caaaatcatt gaaagaagaa gcaaaaagtc tttatgggga aagcaagaga
    29461 gaatcaaagg atgcagaaaa aaatgctctc tttgatttga agaagcgcac aggaaatgcc
    29521 attctaacag aactgaagaa acaggatagt caaataaaac ctttaataga aagtatggat
    29581 cagatgcaat ctatttacaa tgaacgatcc tttcgaacgc ttaaacagtt accaacgaat
    29641 gaatacaaat atagttacga agaattcatg aagcgcagga aacaattcca acaaagagtt
    29701 gtcacgcaac ggagtttgcg tcaattaaat cgaacgatta atgcccatga agaaaaatac
    29761 cacgcaagta aagcctacga agagcaacaa cgaagaattc aaatggaaca agaaagacag
    29821 taaagacagt aggaggaata gcaatgaaac aatatttaga tcaatggaaa gttatagaag
    29881 gatcattaag agaagaacga atcgaacaac ttcccgattg tttagaaaaa gagcatttgt
    29941 ttcagataag agaaatgttg agaaacgaac agtttgatcc aaatcaattt ttagtcgttg
    30001 agtactcagc tactggtgtg tactgttgta atcatgtgaa gggtgaaaaa tattttatca
    30061 ttcaagaata tgagggcaag ttagcgcctt attatactac ttgggaaatg aatgaagagg
    30121 ggatcaataa cttcccgtgt aaaagcattg aagagtctat ttcactcaca gaatgttagt
    30181 tgttaagtga ataaaagaag taaaagagtc ctgaacgtaa ttgtccagga ctcttttttt
    30241 caatgaattg ttttccgcca attcaatgag tggtgcgatt tgcgactaca ttatatcaaa
    30301 agaaagagaa gggaggaaga agaaatggct tattcaacga ttggagttgt tgttgaaaaa
    30361 agcagagaca atctcgtttt tgtgacagaa attcaaacgg gcagagcttt tgtcgtcaca
    30421 gacaaagcgg caaaagcgta tcaaagtggc gatattttaa cgttaaatct gactacgaag
    30481 acgttcgtcg atgcggcaga agattatcc
//
LOCUS       DARPZJ010000028        30349 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.029, whole genome shotgun sequence.
ACCESSION   DARPZJ010000028 DARPZJ010000000
VERSION     DARPZJ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.029"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            171..515
                     /locus_tag="SLE23_001567"
     CDS             171..515
                     /locus_tag="SLE23_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEI8468476.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            516..935
                     /locus_tag="SLE23_001568"
                     /pseudo
     CDS             516..935
                     /locus_tag="SLE23_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1027..1377)
                     /locus_tag="SLE23_001569"
     CDS             complement(1027..1377)
                     /locus_tag="SLE23_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468477.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1343..2674)
                     /locus_tag="SLE23_001570"
     CDS             complement(1343..2674)
                     /locus_tag="SLE23_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HEI8468478.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="SLE23_001571"
     CDS             2930..3496
                     /locus_tag="SLE23_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8468479.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="SLE23_001572"
     tRNA            3641..3728
                     /locus_tag="SLE23_001572"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            4062..5036
                     /gene="bsh"
                     /locus_tag="SLE23_001573"
     CDS             4062..5036
                     /gene="bsh"
                     /locus_tag="SLE23_001573"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEI8468480.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5361..7256
                     /gene="asnB"
                     /locus_tag="SLE23_001574"
     CDS             5361..7256
                     /gene="asnB"
                     /locus_tag="SLE23_001574"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HEI8468481.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNETIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7451..7897)
                     /locus_tag="SLE23_001575"
     CDS             complement(7451..7897)
                     /locus_tag="SLE23_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEI8468482.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8125..8274
                     /gene="rpmG"
                     /locus_tag="SLE23_001576"
     CDS             8125..8274
                     /gene="rpmG"
                     /locus_tag="SLE23_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEI8468483.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8362..8880
                     /locus_tag="SLE23_001577"
     CDS             8362..8880
                     /locus_tag="SLE23_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8468484.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8957..9913)
                     /locus_tag="SLE23_001578"
     CDS             complement(8957..9913)
                     /locus_tag="SLE23_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8468485.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10079..10885
                     /locus_tag="SLE23_001579"
     CDS             10079..10885
                     /locus_tag="SLE23_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468486.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10882..11871
                     /locus_tag="SLE23_001580"
     CDS             10882..11871
                     /locus_tag="SLE23_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEI8468487.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11868..12872
                     /locus_tag="SLE23_001581"
     CDS             11868..12872
                     /locus_tag="SLE23_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEI8468488.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13004..13546
                     /locus_tag="SLE23_001582"
     CDS             13004..13546
                     /locus_tag="SLE23_001582"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEI8468489.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13566..14264
                     /locus_tag="SLE23_001583"
     CDS             13566..14264
                     /locus_tag="SLE23_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEI8468490.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14285..14497
                     /locus_tag="SLE23_001584"
     CDS             14285..14497
                     /locus_tag="SLE23_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEI8468491.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14497..15459
                     /locus_tag="SLE23_001585"
     CDS             14497..15459
                     /locus_tag="SLE23_001585"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEI8468492.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15477..15872
                     /locus_tag="SLE23_001586"
     CDS             15477..15872
                     /locus_tag="SLE23_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEI8468493.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16035..16400
                     /locus_tag="SLE23_001587"
     CDS             16035..16400
                     /locus_tag="SLE23_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HEI8468494.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16397..18208
                     /locus_tag="SLE23_001588"
                     /pseudo
     CDS             16397..18208
                     /locus_tag="SLE23_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
     gene            complement(18270..18437)
                     /locus_tag="SLE23_001589"
     CDS             complement(18270..18437)
                     /locus_tag="SLE23_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEI8468495.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18685..19674
                     /gene="galE"
                     /locus_tag="SLE23_001590"
     CDS             18685..19674
                     /gene="galE"
                     /locus_tag="SLE23_001590"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEI8468496.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19686..21170
                     /gene="galT"
                     /locus_tag="SLE23_001591"
     CDS             19686..21170
                     /gene="galT"
                     /locus_tag="SLE23_001591"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEI8468497.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21194..22174
                     /locus_tag="SLE23_001592"
     CDS             21194..22174
                     /locus_tag="SLE23_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8468498.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22365..23087
                     /gene="tsaB"
                     /locus_tag="SLE23_001593"
     CDS             22365..23087
                     /gene="tsaB"
                     /locus_tag="SLE23_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEI8468499.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23071..23613
                     /gene="rimI"
                     /locus_tag="SLE23_001594"
     CDS             23071..23613
                     /gene="rimI"
                     /locus_tag="SLE23_001594"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEI8468500.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23620..24084
                     /gene="rimI"
                     /locus_tag="SLE23_001595"
     CDS             23620..24084
                     /gene="rimI"
                     /locus_tag="SLE23_001595"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEI8468501.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24081..25097
                     /gene="tsaD"
                     /locus_tag="SLE23_001596"
     CDS             24081..25097
                     /gene="tsaD"
                     /locus_tag="SLE23_001596"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEI8468502.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(25706..26407)
                     /locus_tag="SLE23_001597"
     CDS             complement(25706..26407)
                     /locus_tag="SLE23_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEI8468503.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            26868..28097
                     /gene="arcA"
                     /locus_tag="SLE23_001598"
     CDS             26868..28097
                     /gene="arcA"
                     /locus_tag="SLE23_001598"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEI8468504.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            28188..29207
                     /gene="argF"
                     /locus_tag="SLE23_001599"
     CDS             28188..29207
                     /gene="argF"
                     /locus_tag="SLE23_001599"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEI8468505.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            29322..30269
                     /gene="arcC"
                     /locus_tag="SLE23_001600"
     CDS             29322..30269
                     /gene="arcC"
                     /locus_tag="SLE23_001600"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEI8468506.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
BASE COUNT         9922 a         5198 c         6316 g         8913 t
ORIGIN      
        1 taaaaaaagc gttagcaact atgcttaaaa agcatatcga ctgaataaac taagcattgg
       61 acaggctgaa agactacatt taaaatgaaa tgcgaagaaa caatagaaaa taaagttgcc
      121 ttagaaccat agttgaatca cctaacagtc gtgaagggag aataagagaa atggcagaaa
      181 aacaaaccgc aggacgagat caattaggag attttgcacc aaaatttgca gaattgaatg
      241 atgatgtttt atttggacaa gtatggtcca gagaagaatt atctgctcat cagcgtagta
      301 tcatcaccat atctgcatta atttcaggag gaaattttga acaattgcca gctcatctga
      361 agattggcaa gcaaaatggc attactagtg aagaaatagc agaaatcatt acccatttag
      421 ctttttatgt aggatggcca aaagcttggt cagcttttag tttagcaaaa gaaatctatt
      481 tagaagaaaa tagcgaagat aagaaagagg cgtaaatgac gacaaaacac gaagaaatac
      541 acaatggcgt gatttttcca gcaggtgaaa aaaacgaagc ttacgctcaa gtatttaccg
      601 ggtaaagcta tctgaatatg ttagtgaatg atcccgaagt ttctgttggt gtaggtaatg
      661 taacttttga accaggttgt cgcaatcact ggcatgtcca taaagacggc tatcaaatct
      721 tacttgtgac cggaggagaa ggctggtatc aggaagaagg aaagccagca agacgattaa
      781 tggctggaga tgtcgtcgta acgcacaaag ggattaaaca ttggcatggt gcgacaaaag
      841 acagttggtt tgaacatttg gcgatcactg ctggtaattc agagttttta gaacctgtaa
      901 cagatgaagt gtatgaagga ttggaaaatc aataatgtca agcttgaaca gctcctgaaa
      961 gtagatttta atcgaacttt caggagctgc ttttttgatt cagtctttta taaatagaaa
     1021 atagggttaa taataggaat gagaagcacg tcgaaagatc ttaatattga taatcggctg
     1081 ggcatacatg atttccacgt catcaatcaa actacctaac agatgataat cttcccgatc
     1141 atgtcgggga ttacctaata gttcttgata atagatttcc atactagggt cccgaggatt
     1201 gttcagcaaa tcagcaagta catctaaatc ttctggctga gtttctgccg taccctgtat
     1261 ctctatgaaa agcccttcct cagcaaattc tactccaata cgtatttcag ttatttcatg
     1321 ggaatataaa taagtaagaa gctcatcgat gattcttttt gataattctt tttccaagtg
     1381 tctttttttc ctttctgaca gcggtaaagt tatctagtat cggtacaagg atacctgcaa
     1441 cgaaaccagt tgaaaaacca ctgttatata gatttagtcc tccgtgcaaa gtgctgacgt
     1501 tatggacaag agcaatatgt agtacaccag ctattacacc gtaaaaactg ccgtaaaaac
     1561 cgcttatggg cgcgagacct gtcccaaaca cagctgcaac aagcatgcca gtactggtga
     1621 tctcatgaaa agttccaaac aaagaagcaa taaatattcc gactagtatc ggaaaactgt
     1681 tttttaaatg acaaccaaaa gcactgaaac ccaccgcaga taaaatagca ccgatgacag
     1741 gtccatttaa ctgaccgcca accagcaaaa cataagaaga cagcatcaga ccaactaagc
     1801 ctatgttgat caaagtagca ccaataccag aattagcaat gaaatcagtt gtcaattttc
     1861 cagatgaatc gaaaatttct cgaatcccca aaagccgaaa ggaattataa tagaaaccaa
     1921 ttccgactgt cagcgaaaaa aagccaaaaa taatccaaat gagaggaaag tgatattcat
     1981 tgaaaaccaa tgtattttcg acgattgaat agctgaataa cctcaaaaca gcagtaaaag
     2041 tcatcgcaat caacccagag gtgaatccaa tattataaag tgtgaatcca cgatggaaaa
     2101 ctaaagtttg agcagctaag ggcggaagaa gtagaccaat tgctatgcca gctaaattcc
     2161 ccaataaaat acctatcagt aaaggaaaac gcataccaaa agtgatataa ctaacgaccg
     2221 gtgataatgc gctaccaaac agtccgatca tgatgtactg agaaaaaggt ttattgacaa
     2281 atacagcgta tagatacaca cctaaaatga ttgagataga attataaagg tttttgccaa
     2341 aaaaagagaa accggtaact gttagaatcg aagcaaataa gggaccgttt aaaatcacct
     2401 tgtgccgata agctaaaagc acagaaagta aggtcaaaat ccctacattt atgaatgcgc
     2461 ttccgaaacc gcctaaagca aaataatctg tcaaaagatt gcttggcgag gtaagaatag
     2521 ttagcaatcc actccaatta tcagtaggag tattagaaag caagccaata aaaagaaaaa
     2581 aaacacctgt aaaaccaaga taaaaatact ttcttttctg tgaaacgatt cgtttttgag
     2641 gatgaatata aataacgtca gtttcgtttt ccattacaca ccttcttttt cattttcttt
     2701 aactataact tgaaatgaaa gatttggaca actatcattt aggtcaaaac taaaaatgta
     2761 agggaaccca ttgaatttaa ccaaattttt ttaattttgc aaaaaaaagt taaagaagac
     2821 tgaaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt
     3961 ataaatgcta gtaaatcaat cttctttggc ctttttttga taaaaaaaat actagatgta
     4021 agataaaagt gtaaaaacga tttgttttag gacgggaaac gatgtgtacc gcaatcactt
     4081 atgcaacgaa agaccattat tttggaagga attttgatta tgagatgtct tataatgaag
     4141 tggtcactat tactccaaga aattatcgtt tcgattttag aaaggtaaaa aatttagata
     4201 aacattatgc aatgatagga atagcagctg gggtatccaa ctatccactc tattatgagg
     4261 ctacaaatga aaaagggttg agtatggcag gactgaattt tcctggcaat gctgattata
     4321 aagaattaca agaaggaaaa gataacgttg caccatttga gtttattcca tggatactag
     4381 ggcaatgctc aaccatagac gaagctaaag aattattggc tactatcaat ctagtcaata
     4441 tcgattttag tgaaaaacta cccttgtcac ctttacactg gttattagct gataaagaaa
     4501 aatcgatagt aattgaaagt atgaaagatg gacttcattt atatgataat cctgtcggtg
     4561 tgttgacaaa taatccgcca tttgattatc aattatttaa tctgaacaat tatcgctcgc
     4621 tatcaaatgg aacaccagaa aatcattttt caaaccagat cagcttgaat gtttatagtc
     4681 gtgggatggg aggattgggc ttacctggag atctctcttc tgtttctcga tttgtaaaag
     4741 ccacatttac taaaatgaat gctgcatcag gtgattcaga atctgaaagt atcagtcaat
     4801 tttttcatat actaggctca gtcgagcaac aaaaaggagt atgcgatact ggagaaagaa
     4861 aatacgaata tacgatttat tcttcttgct gtaacgttga taaagggatt tattattatc
     4921 gtacgtatga agacagtcaa attactgctg taaatatgaa taaagaagac ttggatcgtc
     4981 atgaattggt cagttatcca gtcataaaag agcaacagat aaactatgtc aattaattaa
     5041 tgaatagatc cgtttggtat catattttct gatacagtca taattagaca cgatctttag
     5101 gtcgtgtctt tttttgctgg tttttttgga aatagcatcc actaatattt ttttaacacg
     5161 aagagaataa ggtagcctca aaaaagaaaa catggtaaat tagatattgg gactttattt
     5221 tctgtaaaaa cagaaacttt catcttttgt tttcacgtga cgaaattgta agagagaaaa
     5281 tattcgtccg ctatttattc tatgataaga tgcatatgaa tgaaataaac agtaatttta
     5341 tattaggatg tgaaagttaa atgtgcggta ttgtaggttt tgttaacgac aaggacaaca
     5401 aaaaaacaat tattaataca atgatggatc gaatcgttca ccgtggacct aatagttcag
     5461 gagaatatat cgataaacat gttgctttag gattcagaag attaagtatt attgacttag
     5521 agggcggtac tcagcctatt tacaatgaag atcggacaaa gatcattatt tttaatggcg
     5581 aaatctataa ttaccagcct ttgagagaag aattgattgc agctggccac gtttttcaaa
     5641 cacatgcaga tacagaagtc cttttgcatg gttacgaaga atggggaaca gaattattgc
     5701 aaaagatccg cggaatgttt gcttttgcta tttgggataa tgaaaagaat gagttattcg
     5761 gtgcaagaga ccactttggg atcaaaccat attattatgc agaaatgaac ggaacattta
     5821 tgtttggttc agaaatcaaa agttttctgc ctcatcctga ttttaacaaa gaattgaaca
     5881 aagaagcgtt gaaaccttat atgactttcc aatattctcc attaaacggc gaaacattct
     5941 tcaaagatgt ctatcgtttg cctgaaggcc attattatac gtataaagat ggaaaaatag
     6001 acattcagca atattgggat gcagattttg aaacaaaaga aacgcattcc cgacaagaat
     6061 ggatcgaaaa aatcgacgaa accgttcaag cttctattga agcacatacg gtcagtgatg
     6121 tagaagttgg ttctttctta tccagcgggg ttgattccag ttatgtaacc tctgtattga
     6181 aaccagatca ttctttctca atcgggtttg atgataaaac ctataatgaa acgattgaag
     6241 ccagaaaact aaccgaacta ttggacttag ataatacagc agcagtgatc gacggagaca
     6301 tgtcgttcaa agcattccct ttgatccagt atcacttaga tgaacctgat tcaaatcctt
     6361 cttgcgtacc tttgtacttt ttagcaaatc ttgcttcaca aagtgtgcgg gtagtccaat
     6421 ctggagaagg ggcggatgaa ctgtttgcgg gataccaaac gtatggattc catacgaatt
     6481 caaaattcat ccgtgtgatt gctcaaggat tgaaaaaatt accaaaagga acacgctata
     6541 atttaggacg taaaatcgga aaaatgaaaa atttccatgg acggatccat ttatatgaat
     6601 cacttgctcc tgcaaaagaa tattttatcg gtcatgctcg agtgttcgaa gaatcagaag
     6661 catcagaagt gttaacacca aaatatcaaa cagcaccatc tgtggatgaa atcatgactg
     6721 ttcattacga gaaaacagaa ggaatcaaag atgaagtcaa taagatgcaa tatgtcgatc
     6781 ttcatcaatg gatgccaaaa gatatcttgt taaaggcaga taaactttct atggcaagtt
     6841 ctttggaagt ccgagtacct ttattggata tcgaagtcat gaaattggct caacaaatac
     6901 caagtaagtt tttattgaat caaaacaaca caaaagatat tttcagacaa gctgcgaaca
     6961 aacatcttcc ggaaaaatgg tcgaatcgtg tgaaattagg attccctgtg ccaatcaaag
     7021 cttggttgaa agaagaacac ggctacgaac aagtcaaagc attgttcgaa gcagattttg
     7081 caaaagaatt ttttgatcaa gaaaaaatca tgaagttgct agatgaccat cacgaaggac
     7141 gtaaagaaga gcaaagaaaa atctggacaa tcttcagttt cttgacatgg tataaagtct
     7201 actttgtaga tgaaacgatt ccgcaagcag aagcaatcga ctatgtgact gtttgatgaa
     7261 aatcaaatat caataaaaaa gaggttttct cctaccgttt aacactgagt gataagaaac
     7321 aatttcaaaa aacagctctt cccgttttat agatattatg acttatggtt cggagttggc
     7381 agaggaacac cattgtttcg aacataaggg ggttgtgaca cgattttcgt cacaacccct
     7441 ttacatatgt tcaataatcg atttcttttt cttttgtccc atctttttta taaatgaaca
     7501 aagttgattc tttgttttgt gctacttgct ttcctttttc gattgcttct ttttttgtat
     7561 caaaatggtt gcttgccttt tttgcccctt tagatttcac gatccattgt tcttcctcat
     7621 attctacgat cacatctgaa tcaagcagtt ttccagcacg aggattcgta tcgtgttcat
     7681 ccgtcttgct tggatttttt tctttttcga aagttcgttt ttctgattca ctagcatctt
     7741 cataccattt ttttgcttga tcaatggcaa ttgggatcgc acggttatca gggtaccctt
     7801 catctaataa tgcatttgcg atgtcgattg ctttttttct tgtcaattta tctaagtttt
     7861 tcattgatgc aggaaagtcc ttcatgttcc atggcatatt agtatccccc tttattaaaa
     7921 aacataatct atataaacaa gtgtaagggt atttatacaa aaagaaaaag attttgtttg
     7981 agaagtaaaa ccgttgtatt tatcgtcaag tagttttact taacaaaatc gtgaaaaaca
     8041 ctagcaatct agaaaaaatc atggtaagat aatcaagtct gagagtcatc ttagaggatt
     8101 cttgtaaaaa tgggagggaa aaacatgcgc gtaaacatca ctttagagtg tacttcttgt
     8161 aaagaacgta actatctaac aagcaaaaac aaacgtaaca atcctgatcg tttggaaaaa
     8221 caaaaatatt gcccacgcga acgcaaagtt actttgcacc gtgaaacaaa ataatgtttt
     8281 taaagttctc aattccttgc tggtcaaaga attgagactt tttttatctc aaaacatcta
     8341 aaatcataag gagcggataa tatgtttatt tccatgtggg cacaagataa aaatggtctg
     8401 atcggcaaaa atggtttgtt accatggcga ttgccaaatg atatgcgttt ctttcgcgaa
     8461 catacaatgg atcgaatttt agtgatggga agaaagacct atgaaggaat gggggatctt
     8521 tcacttcctt atcgccatat catcgtgttg acaacgcagc caaattttcg cacgaaagaa
     8581 aatgcggaag taatgcattc gatcgatgaa cttttgtcgt atagtcaaac gatctcagaa
     8641 gatatctatg tttcgggtgg tagtcggatt tttcaagaac ttcttcctta cactggtcgg
     8701 atctggcgaa cattgatcga tagcacgttt gaaggcgata cgtatattgg gaatattgat
     8761 ttttcagact tcgcccttat agaggagtat gaggggataa cggatcaaga aaatctatat
     8821 gcccatcgtt ttcaaaaatg ggaaagagta aaaaataggg ttgcttcaaa agaagaataa
     8881 aatctatgcg tctagtttgt taataagaaa aaaagcatat cacgactaat cgtgaagatg
     8941 ctttttttag ttaaaatcaa tttagttttt ctttgatatc attgaccatt tcctgactgg
     9001 caataggtcc gttatatagc caactagatt caggtccgaa ttgcagtaca tgattgtctg
     9061 tcactgcttt aagattcttc cagcttggtt cattgaacat ggcagcatct ttgtcactgt
     9121 tcacaaggat gatgtagtca gcatctaatt cagctagctt ttcagaggaa acagcagacc
     9181 agtcagaagt ggcttttttg gagacctctt ccactagatc aggaacacca aattccagat
     9241 cgtcgtatac gattcttcca cttgaccgat ttttgctgac cataaaggct gagttgttgg
     9301 tcacccacaa cactgcagct gtcttgttct cgattttatc tgctagttct tctcgagttt
     9361 tcttgatgga tttttgataa tcggaaatga tcttttctgc ctctttttct tttgccaaag
     9421 ctttgccgac atcttttagt tgttcttccc atgtgacatc tgttccgttt tttacaacat
     9481 aagttggcgc gattttgcta tattgttcgt atttcccgcc ttcgacagta gcggaagaag
     9541 aaatcaacag caaatcaggc tcaaagctta acactttctc ataaggaagg tcataagaaa
     9601 tcgttgggac atcctttaaa tcatcttgca gataatcttg aatggaacca ctgccaacag
     9661 tccactgggc gataggtttt tcccctagtg caatcagata gtcttctaag taactgccga
     9721 tgatccgttt gggcgcgttt ggaatctcta ctttatgtcc aagtgtatct gtgactgtat
     9781 gagtactatt ggatgaagtc gtcgaattgg cagttgtagc tgtttcttta tctgaagagg
     9841 gggagcaagc gctcagtact ccagccagca gcaatatgct agataatgtg aatacttttg
     9901 tttttaattt catttctttc ctcctaacat aattgagaat ctttctcatt ggttattatt
     9961 cctgatattt cgaacgctgt caaccgcttc atttggctat agatatgaaa gtagcgcttg
    10021 acgaaatgtt gaaacagcgt cataattgag aatgattttc agcgaaagga tgggtgaaat
    10081 gacgagatta agagcagctg acattgcagc cggctacgaa aacaaaaaaa tcattgaaaa
    10141 catgtctgtt acgattcctg aagggaaaat cactagtttg attgggccaa atggaagtgg
    10201 aaaatctact ttattgaaaa gttttacccg tatactacct gtgaaatcag gaaagatcat
    10261 tgtcaataac tctgatatct ctacatacag ttcaaaagaa cttgcaaaaa aaattgcatt
    10321 attagcacaa actagtgaac accctacagg tatgacagta gaagaagtag tatcttacgg
    10381 acgataccct tatcaaaaac tgttcagtgg catggacacg caagatcatg aagcaatcga
    10441 gtgggcgttg gatgctacag gtctagctgg atttcgtatg cgggatatcg caacgctgtc
    10501 tggtggacaa acccagcgtg tctggatcgc tatggcgctt gctcaggaaa cagatatctt
    10561 gatcttggat gaaccgacaa catttttaga tccggcacac caattagaga tcctacagtt
    10621 attgactgaa atcaatcaaa tgaaacaaac aacgatcttg atgtcgattc atgacattaa
    10681 tcatgcttca cgtttttcag attatttatt agcaatgaaa aacggtaagt tgatcacaga
    10741 aggtacacct gaagaagtga tcacaaaaga gtgtatgaaa aaaatatttg agattgatgc
    10801 aacgattgtc acgcttccaa gaacaaataa accagttttt ctaacctatg atttgttgcc
    10861 aaaagagcag gaggatcaat tatgaggact atgaagaaaa atagactcct gcttttggtc
    10921 tgttttgttc ttttgattat tttttttgtt gctctttcaa atggcgcagc gactgtggga
    10981 aaagcagatt tttggcaggc gttgtttgat tttgatagat caaaacaaag tcaccaaatc
    11041 atacgaaata ttcgtttgcc tcgtgtggcg ggagcatttc ttgtagggag ttgttttgca
    11101 ttgagcggtg cattgatgca aggagtgaca agaaatcctt tagcagattc aggcttacta
    11161 ggaatcaacg cgggtgcttc gttggcaatg gcccttagtt ttgctttttg gcctaaagct
    11221 tctgattttt ctgtgtttct aatgtcattg gcaggttctt ttgctgtaac tttgctcgta
    11281 tttggttttt tgcagttttc gaaaatgggc atgaatcctt tacagctgat tttagctggc
    11341 gtagctatta gttctttttt tactgctatc agccaagcac ttacccaatt ctttaatctg
    11401 cagcaggatc ttgctttttg gtttgtaggc ggagctgcca atatcacatg gaaacaatta
    11461 gcagtattgt ttcctttata tatacttgct gttttggttt ctttttcatt aggaaaagca
    11521 atatctttga ttcatttgag tgaaacacat gcattagctc ttggaagtca tcctaaacga
    11581 acgcggttga ttgttttctg tctagttgca gtgttagcag ccattgccgt ttcgttagtc
    11641 ggacctgttt catttattgg gctgttggtt ccgccagttg ttcgcggaat ggttggaacg
    11701 gactatcgtt atgttctacc tgtctctttt ttagttggcg gtggattggt tatgttggcg
    11761 gattttacag cgaggatgat caatccccct tttgaaacac cttttggatt agtcattgca
    11821 ttgattggcg ttccgttttt actgatacaa gtaaggaggg aacaacggtg aaaaaaatat
    11881 attggacgtt ctatttcttg ctttttgtac ttgtcatcct gtctataggt agtttaatga
    11941 ttggtacgcc ttttatttac ctggatcagc tttttgccac gttcataggg aaagaatcat
    12001 cttctttggc gctgattgtt agagaatttc gagttcctcg attactgatc agtttattag
    12061 caggagcttg tcttggcgtt tctggttata tcttgcaagg agtaacaaga aatgaattgg
    12121 cagattctag tatattgggc attaatgccg gagcaggatt tttagtgatg ctttatttag
    12181 gtttcttttc gcactattcg ctgccgtttc tattgctagt tgtagccttt ctaggtggtg
    12241 ttttagctgc ttgctgtgtc tatcttgcgg cctatgatcg aaatggcttt ttgggtatga
    12301 atcgaatctt attgtccggt attgccgtta atgccggcct ttctgcatta acattgctat
    12361 gcacgatcca attatctaag gaaaattatg gatttgtgaa tgcatggtta gcgggatcaa
    12421 tctggggtgc gagctggcct tatgtttggg cattgcttcc atgggcggtt atcttaattc
    12481 cgctaggagg actttatgca cagaggattg tattgctatc atttggtcaa gaacgcgcgc
    12541 aaggattagg ccttaacgtg gctaaaagtc aaaaaatcct tttgttgtta gctgttgctt
    12601 tggcaagcgg tagtgtagcg gtgacaggta gtttatcttt tgtaggacta ctagctcctc
    12661 atgctgcgaa gctagtcgta cgtaaagaaa ataactggac ctttgttctg agcggtttgt
    12721 tcggttccat ttttctgctt agtgcagata tggttgctag agtgattcta ctaagtgggg
    12781 aagtacctac aggaattttg attgcccttt ttggtgcgcc atattttctg tatgcacttt
    12841 ttatcagaca aaaacacgcg ctgaacagtt gaaattcatt aaaaaaggaa ggccaatcat
    12901 ttctaggtct tctttttatt ctatttatgc atttatttga aagttcgatt gctatttttc
    12961 tttttttcct ataccatttt atgagagaag gaagggtgag tttttggacc aattgaaagt
    13021 aagattacgc cggaaaggaa tcgaaaagct gaaaaatctg gccaaaagtg gcaagaaaaa
    13081 ggaaaaagaa cagcgaatct ataaacagct attcgccagc gagtactgga agtcagcaaa
    13141 agtgataggg acgactttat cgaatgaatt tgaactggat acacagccgg ttatccaacg
    13201 agcagaaaaa gaacaaaaga aaatagttgt acctaaaact ttgccgaaac gtcagatggc
    13261 gttttatgaa atggatgaac agtccgttct tgtacgttcg agttttggtg ttcttgagcc
    13321 acaatcagag aagctctatt tgccggagat gatcgatctc ctcattgtac caggtattat
    13381 ctacaataga gccggttatc gaatcggttt tggcggtggt tattacgacc ggtatttaaa
    13441 taattttcat aaaaaaacat gtagccttgt ttttcgtgaa caattgaatg aacaatggca
    13501 accggagagc tttgatcaga agatccaaca attgtttatt gactaaaatg aaatgggagg
    13561 ttttcatgaa ttatcaacag caaataaaat tgcgtgcatg gttaagacga ccgttatgga
    13621 cctatgcttt tttagggata cagacagcgg tcttcctcat gatggaatta tttccgcgac
    13681 ttgagatccc ttattatgcc ggaatgtatg gtccttatct tgttcacttc aatgaatggt
    13741 ggcgtttagt gacaccaatc ttcatccatt ttggactgat gcatttcgta atgaactcac
    13801 tgatactgta ttttatgggg cagcaaatcg aggcaatcta tggccattgg cgttttttct
    13861 tgatttatat gttcagcggg ataatgggaa atacagcaag ctttgctttt aacgaagcga
    13921 atgttctgtc tggtggtgca agtacttcga tattcggttt gttcggtgcg ttgtttatct
    13981 tagggtttca ttttaaacat aacccagcga tccagcagct agtcagacat tttcttttat
    14041 ttattgtgtt gacatttgtt tttggtcttc tggatacctc tgtagatgtt tggggacatg
    14101 tcggtgggct aattggcgga ttagtgttag ggaatgtttt gggtctaccg aaacaacaga
    14161 caagctattc gatacaccaa aggattcttt ctacactagt ttttgtattt ctttttgtaa
    14221 tatgtatttt actgggttta aaaaaatatg gtttacttgt ataatatgaa ggaagtgctt
    14281 aaagatggag agcttatatg atgtacagca gctgttcaaa aaatttggca tctttatcta
    14341 tgtgggtgca cgcatctatg acattgaatt aatgactatc gaattgcgta atctgtatga
    14401 tagccgtttg attgatcatg atacatacat gacagcgtgg cgcatattaa aaagagagca
    14461 ccgaattgaa gaaagccgaa agaaaggaaa tttgtaatgg acaagaagat tattgggatt
    14521 gatttaggtg gaacaacagc aaaatttgca attttaacac cagaaggaga gattcagcaa
    14581 aaatggagca tcgataccaa tattttggat gatggtaagc atatcgttcc tgaaatcatt
    14641 gaatcaatca atcatcgttt gaatttatat aatatgaaag ccgaagactt tatcggaatc
    14701 ggcatgggta ccccaggaag cgtggacagc gaagctggaa cggttattgg tgcgtataac
    14761 ttaaactgga cagaagttca atttgtgaaa aaactgatcg aggcaggaac aggaatcaaa
    14821 ttcgctatcg ataatgacgc gaatgttgct gctttaggtg aacgatggaa aggtgctgga
    14881 gaaaacgatc cagacgttgt attcgttact ctaggaacag gtgttggcgg aggtatcgtt
    14941 gctggcggaa atttgattca cggcgtgagc ggagctggag gagaaatcgg acatatcact
    15001 gtggatcctg aagggttcga atgtacttgc ggtaaacgcg gatgtttaga aactgtatct
    15061 agcgctacag gtgtggtacg cctaggtcgt ttcttggcag aagaatacgc aggggattca
    15121 aaactgaaag caatgctaga caacggagaa gaagtaacaa gtaaagatat ctttgaaatg
    15181 gctcaagaag acgatccgtt tgcattgatg gttgttgatc gcgtatgctt ctacttaggt
    15241 ttagcttgcg gaaacttggg gaatacatta aatccgtcaa gtatcgtgtt aggtggagga
    15301 gtatcggcag caggagaatt tttacgtagc cgtgtagaga aatattttaa agaatttact
    15361 ttcccgcaag taagagaatc aacaaaaatc aaattagcag agcttggtaa tgaagctggt
    15421 gtcattggtg ctgcctcatt agccttgaaa tttgcttaaa aaaacggagg cattacatgg
    15481 ttttatgggt aattaatatc attttgctat tgattgtgct tgcaatcatc ctttgggaag
    15541 tctatctacg agtaatggcc aaacgttcag caacgacttt gacagaagaa gaatttcgag
    15601 aaggaatgag aaaagcacaa gtaatcgatg ttcgcgaaaa agatgtgttt gatgctgggc
    15661 atattttagg tgcaagaaac atcccttaca ctgttttgaa agattcatta ggatctattc
    15721 gaaaagacca gcctgtctat atttacgatc aaaagaaaag tttgagcatc cgtacagcaa
    15781 ataaattacg taaagcaggt tatcaagaga tttatttact taagggtgga tatgacggat
    15841 ggtctggaaa aatcaaaagt aaaaaagtat aaaacagatg attgtatgac agctttaaaa
    15901 accgaatcaa tcattagatt ttgaccaaga tcacatgaac ggcgcaatgg atagttgtgc
    15961 cgttcatttt ttttattttg tgctattatc tacatatata agctaagcga aaaggtagaa
    16021 agaaggaaac aactatgatc aaattaaaac gtgtttacct tgatgctgaa aaagaggatg
    16081 gctatagaat actcgtggat agattctggc cacgaggaat ttcaaaagaa aaagcgcagt
    16141 tagatctgtg gttgaaagaa attgcaccta gtaatgaagc acgcaaaact tttgaccatg
    16201 taccagaacg atttgcttca tttgcaaaga aataccagca agaattgatt ttcgaagaag
    16261 aaaagaagca agctattttt aaactcagtc aacttatgaa agaacatcca gtcattactt
    16321 ttgtttatgg tgcaaaaaat gaacatcaga accatgctgt tttattgaaa aaatttatcg
    16381 aaatggaggc atgcaaatga aaatagggat cattggtgcc ggacctagag gattaagtgt
    16441 agcagaaagg attctccata ataatcagga cagacattct cttgaacttt ttcttttcga
    16501 tcccaatggt cctggaggtc gagtttggcg gttgaatcag ccaccggagt tattaatgaa
    16561 ttctgtttct caacaagtga cgctttttac agatgaaaca ttgtccagtg gaggattggt
    16621 aacacaggga cccaacttgt ttcaatggag taaaggacct gctacagatt atatcgaaca
    16681 gacggtaacc aaaaataagc aactaattat agaagaaatc aatcgtctgg aaaaagatca
    16741 gcaatctact cgatgtttat acggactcta tcaacgctgg tttttctcaa agttgcaaga
    16801 agaatttcca gcttctattc agtttgttta ttctttagta aaaaaagtaa gcaaaagaaa
    16861 agatggttat cttttacaga cagatcagca aagctattct atcgatcagc ttgttttagc
    16921 aagcggtcac tgggaaaatg atgagacaga agaagaaaga gtgtgggtag actacgcaaa
    16981 gaaaaatgtt ttactgtatc agcttccttc taatcctgca gatgtagatc tttcgaagat
    17041 accgcctaaa gaaaatgtct ttttaagagg tctaggctta agtttttttg attatgtcgg
    17101 attgtttaca gtatcaagag gagggcgctt cgagaacgaa aagggaaaac tggtctatca
    17161 tccatcaggc aaggaaccga ttgtatacag tggatcaaga agggggctcc cttattaccc
    17221 tcgaggaaga aatcaaaagc aaggcggagc aatggcatga ccacggttac taacaaatga
    17281 aaacctggag caatggcatc agtcgggatt tttgactggc gaaacatttt ttgactatct
    17341 gaaaaaagac gttgagttgt tttattacaa gaaaatcatc gaagaatatc acttgccgat
    17401 tccaaagaaa aattttgagc atgattttct ctccctctct tcagaggagt gtctcggaaa
    17461 gcatccagca ctaatccctt atagatggga ttggtcgtat ttagaaactc ctcttgccta
    17521 tcagaatgag cccttttcag aagctagccg aatatttatt gaagggcaga taaaagaagc
    17581 ggaaaaaggc aattgcacag gagcatttgc ttcaacattt gatgcattaa aagactggcg
    17641 tgatccaatc cggcaggcta ttgaatggca cgttttttct gctaaggaat acaaagaaat
    17701 actatgggga tggtttactc atctaaatag ctttttaacg atcggtccgc caatcattcg
    17761 gacgaaagaa ttagcagcac tgatagatgc gggtattttt catttgatcg aaccgccatt
    17821 tgatattcag caaaagcaca accgctatgt tatttctcta caagataaag aaatcagcag
    17881 tcgctatttg attgaagctc gattgccaca aacaagcttt tctcgttcaa gtaatcctgt
    17941 cataaaaaat ttgaaggaaa acaaacttgt tcgccctttt tcattttcag ataatacagg
    18001 aagttatcat tcagaagcta tagatgttga gcgaggtacg aatcgcgtga ttgatgcttc
    18061 aggggaaatc cagtctgact tttattgcta tggaatacct gttgaaggtg tggattggct
    18121 aactgcagca gtagctagac cttatacaga tccatggaat ctgagacagg cagataaaat
    18181 agcacaactt atattgactg acaaataaaa atacgcatga tgacttatct gttttttaga
    18241 aagtcttcat gcgtattttt aaataattat taacgagaaa cgcgtttacg cattgctttt
    18301 ttacggtttt cttcgatcat tgcttctttt tcgtcaattg gatcgatcac tgtttttttc
    18361 acagaagcaa ccaaaccagc aacggcagcg gctgttgcca gacttcctac taatattcca
    18421 gatacaaatt ttttcattga atccacctca tttattattt gttatatcta ttatggaaca
    18481 aaagagaaaa aaaggctagt tttacgtttg tttgtaaacc tttgcaaaaa atccttgaaa
    18541 atgtttacta aatgttttat tataaattta ccatatgaat ttacgaaatt ttactttgtt
    18601 tgttttcacc ataaaagtaa acttcgtttt ttaaattata tagaatcaac aaacacaatt
    18661 ttactaatca aaggagtgtt ttttatgaca attttagtac taggcggagc cggttatatc
    18721 ggttcgcacg ctgtagacca gctagttcaa aaggggtatc aagtagctgt ggtagataat
    18781 ttgctcacag gtcacaaaca agcagtacat ccagatgctc atttttatga aggagacatc
    18841 cgggataaag aatttctacg ttccgtattt gaaaaggaac cgattgaagg agtaatccat
    18901 tttgctgcaa gctctttagt aggagaatct gtcgaaaaac cattgatgta tttcaacaac
    18961 aacgtatacg gtatgcaaat cttacttgaa gtcatgcacg agttcaacgt gaataaaatc
    19021 gtattctctt ctactgcagc aacttatgga gagccgaaag agtctccaat cacagaagat
    19081 acaccagcta atcctaaaaa tccgtatggt gaaagtaaat tgatgatgga aaaaatgatg
    19141 aagtggtgtg accaagcata tggcatgcgc tatgtcgctt tgcgctactt caatgtagcc
    19201 ggagcaaaag cagatgcatc tatcggagaa gatcatacac cagaaacgca tcttgtccca
    19261 atcattttac aagtagctct tggtcaaaga aaagccttgg ctgtttatgg agacgattat
    19321 gatacaccag atggaacatg tatcagagat tatgttcaag tagaagattt gattgctgca
    19381 catattttag ctttggaata cttgaaagaa ggaaatgaaa gcaacttctt caatttaggc
    19441 agcagcaaag gatactcagt caaggaaatg ctagaagcag ctagagaagt gacaggaaaa
    19501 gaaattccag cagaaatagc accaagaaga gctggagatc ctagccgatt agtcgcttca
    19561 agtgaaaaag cgagagagat tctgggctgg aaacctgaat acacagatat caaagcgatt
    19621 atcaaaacag catgggattg gcatgtcagc catccaaatg gttatgaaga ataggggaat
    19681 gagatatgtc aatcagtcaa acgatttgtg attttgccac acttgcgatc gaagctggcg
    19741 gatggatgga aatggaccgc ttatatttac agaatcgtct tttagggatg gtaggagaag
    19801 atgctctaga aagcattgaa gtaagaccag ttaaggaaga atctgtagac ttattggatc
    19861 agcttgtcgc taaggcaaga gaaaatggtg ttctttcaga attgccagca gaacaagaga
    19921 tttttgaagc gcaattaatg gattttctca caccgccacc ttcagtcgtc aatgcattct
    19981 ttgcacagca ctattcgaaa agcccagagg aagcaactga gtatttcttt aatttaagta
    20041 agaaaaatga ctacatcaaa acaagagcca tcgcaaaaaa catcaaattt ccggcagagt
    20101 cggagtatgg tgaactggaa atcacaatca atttatctaa gccagaaaaa gatccaaaac
    20161 aaatcgcagc agaacgcgag gcggtaaaag tagactatcc tacctgcatg ctttgcatgg
    20221 aaaacgaagg atatagaggt cgcttgaact atccagcccg caccaatcac cggattattc
    20281 gaatgaatct agacggtgaa agctggggat tccaatattc cccttatgct tattacaatg
    20341 aacattcgat cattttatca gaacaacacc gcccgatgaa aatcacaaag gaaacatttg
    20401 ctagactgct tcggattact gaagtcttgc ctcattactt tgttggttcg aatgctgact
    20461 taccaattgt tggaggatcg attctttctc atgatcatta tcaggcagga cgtcatgaat
    20521 ttcctatggc aaaagcaccg atagaaaaac ttatcaaact agaagattat ccgcaagtca
    20581 tcgcaggagt cgtgaaatgg ccgatgtctg tgatccgttt gcaatcaaca gagaaaaact
    20641 tgcttattga agcagctaac tcagtattgg aaaaatggaa agcatattcg gatgaaacag
    20701 tatctatcag agctttttca gcagatggta caccacacca tacgattacg ccaattgcac
    20761 gaagaaggga caattacttt gagttggacc ttgtccttcg agacaacaat gtttcagaag
    20821 aacatcctga tgggattttt catccacata aagatgtcca acatatcaaa aaggagaaca
    20881 ttgggttgat cgaagtaatg gggcttgctg ttttaccacc tcgtttgaaa ccagaactag
    20941 tagaagtaga gcatttctta ttaggagaag aaaaccagat ggctgaatat catcgtccgt
    21001 gggcagaaca attaaaaaaa gaacatcctg atttgacgaa agatacggtc accgatgtcg
    21061 tacaaaaatc tgtaggtcag gtttttgcac gtgtactgga agacgctgga gtattcaagc
    21121 gagatgaaaa aggacaggca gcgtttgaac gatttactgc gattttataa acgtaaaaaa
    21181 ggaggagaga caaatggcaa caattaaaga cattgcgcag ttggcaggag tttctcctgc
    21241 tactgtttca agagttctca actatgatcc tgatctttcc gttggcttag ccacaaagca
    21301 aaaaattttt gaagcagcag aacgcttaaa ttatacgaaa catcgtaaaa atgcagcaaa
    21361 tactaagcaa acgcttcgcc tgatccagtg gtacgacgat acggaagagc ttgaagatct
    21421 ttattattta tctattcgcc taggaatcga aaaaaaggca gaagaagcaa acgttacttt
    21481 attgaaagaa acgtgggatt ccattagtga tcttccggca gatggaacga tcgcactagg
    21541 aaaattcgac gaagctcagt tattagaaat gaaaggatcc caaaatgcct tgcttttggt
    21601 agattctgac ggcacttctc aaggaatcga ctctctagtt gtcgacttta agtcaagtgt
    21661 tcaaaaagtc attgaacact ttgtctccca taaagcgcaa catatcgcta tgcttgctgg
    21721 aacagaatat acgaagaaaa accatcagcg gctaaaagat cccagaatta tggcatttca
    21781 acaagttttg gcagaaaaag gctacgacga aggtccaatt atcgaagcag atttttctgt
    21841 cgagtcagga tatcaagcag tgaagcagta tttaaaaacg aatccgcatg ttcctgatgc
    21901 gctttttgca gctaatgatg cattagcgat tggcgcactg aaagcgattc aagaaaaagg
    21961 tttagtggta ccagaagata tttctgtgat gggcttcaat gatgtcagtg tagcgaaata
    22021 tgtaacgccc tcgctttcta ctgtaaaagt ttataccgaa tggatgggag agctagcagt
    22081 ggagacgatt cttcaattaa gtaattccaa agcaccggtt tcaagaaaga ttattgtgga
    22141 aacagagttg attattcgag aatcaacgaa ataaaagatg gaaaagctgt gggaaaatgg
    22201 agtgataccg cagctttttt gtgtttcagg aaggggcaaa atttgcccgc cagcagataa
    22261 tcatgtatta ttgtactagt tttgcctttg gtattttcat cctcagaata aaaaagtatg
    22321 ctacaatgga aggcgagaat gtcatagcag aaaggatcaa atatatgatt acattaggaa
    22381 tagatactgc aaaccaaact ttggcgatcg gtgtggtaga agacgaacaa attcttggac
    22441 aaatacaaac aaatatcaaa cgcaaccaca gtgtaacact gatgcctgca atcgaccaat
    22501 tgtttgcaga tcttcaaata agtccaaaag acattgaccg aatcgcggtt tctgatggtc
    22561 ccggttctta tacagggctt cgtataggtg taacgacagc aaaaacgatt gcttatacat
    22621 tagataaaga gctagtagga gtatctagtc tgaaaaccat cgcggctaat tgcatcggtg
    22681 tggataatat tattgtgccc atgtttgatg ctcgaagaaa aaatgtatac gctggggcat
    22741 accgctggaa agaaaataga ttagaaactg tacttgaaga tgtacatatt tctgcttctg
    22801 atttgttcac acaactacaa aagctgaatg aagctattta tttcgtcggg agtgattgtc
    22861 acaaattctt ctctgaaata aaggaaatat tgcctagtgc gatgattaat acagttccag
    22921 catgggatat tccaagtggt gtaactgtgg ctcaattagg tgctttagtt gaaccagttg
    22981 cagagaaaca agcttttctt cctcgctatt taaaacgagt agaagcagaa gaaaaatggt
    23041 tggagacgca cacacctgga gacgaaagtt atgttgaaaa aatttagagc gtatgccaga
    23101 agcttttttc aagataaaat gatttataca gaaaaaacag tcgaacaaat cgatcgtcgt
    23161 tacgtactaa gagaattgac tacagaagat atcaaagagc tgctggatgt cgaacgagaa
    23221 gtctataatg gcgaattgcc atggacaaaa agtgccttta tatcagaatt gaagtcaccg
    23281 cttcctcatc tatatctagg tatctttgat aatggaagaa tgattggttt tatcggttca
    23341 agagcgttcg gtttagattg ccatatcacg aatattgccg ttcgaccggc atatcagcgt
    23401 aaacgaatcg gttcgctgct tattgacgaa atcgagaact ttgctataat gaatcgctgt
    23461 gagacgatgt cattagaagt gcgtatgagt aatcaagatg cacaaagact ttatcggaaa
    23521 ttggggtttc aagcaacaac gatcaaaaaa agatattaca ctgaaacaaa agaagatgcg
    23581 ttggatatga taaaactttt agaaaatgag tgagattagt tgatttgcag aaaaaaagat
    23641 tttgatgaag cgtacttggc agaatgcgta tggatgatta gcgaaaatgc ttatccacat
    23701 ggttcacctt ggacgaaaat gcagtttttg gcagacatcc aacagcctca ctctgattat
    23761 ctgcttttag ctgaagataa ccagatctgt ggctttattg gatactcgaa agtaatagat
    23821 gaagtcgaga tcacaaatat tgctgttgca gtttcagaac aaggaaaagg gcatgcacgg
    23881 catttgttac aattactgat tacggaacaa ataaaagatt cgctgcatgt ttttttagaa
    23941 gtacgtctat ctaatgaagc agcaagaaaa ctttatgaat cagaaaagtt tcgtatatta
    24001 ggtaaacgga aatcatatta tcgcaatccg acggaagatg cgatcattat gagcagaaag
    24061 ttaaaaacgg agacgatgaa atgaatgaag aattgattct ggcgattgaa tcaagttgtg
    24121 atgaaacgag tgtagcggtc gttagaaatg gaacagagat cttatctaac atcgttgctt
    24181 ctcaaataaa cagtcataaa cgttttggtg gcgtagtacc tgaagtagct agccgccatc
    24241 acgtagaaca aatcacctta tgcttggaag atgcactggt agaagctggt gtgtcggcag
    24301 aagatttatc ggcagtcgct gtcacttatg gaccaggact tgtcggctcg ttgctgattg
    24361 gtatttctgc agctaaggct tttgcttggg cacaccaatt gccgcttatt cctgtaaacc
    24421 atatggcagg gcatatctat gcagcccgtc tggttaaacc attccagttt ccattgatgg
    24481 cacttcttgt tagcggagga catacagaat tagtctatat gcaagaagat ggatcatatg
    24541 aaatcattgg ggagacaaga gatgacgcag caggagaagc ttatgacaaa gttggaagag
    24601 tattaggtct ttcttaccca agcggaaaag aaatcgatca gctagctcat cagggaaaag
    24661 ataattacca ttttccgcga gcgatgatcc atgaagataa ttatgatttc agttttagcg
    24721 gattaaaaag tgcatttatc aatttggtgc ataatgcaca acagcgtgga gaagatctag
    24781 acaaaaatga tttagcagct agctttcaag caagtgtgat cgatgtattg attactaaaa
    24841 cacttcgagc ttgtcaaaat tatccagtca agcaactgat tatagctgga ggtgtagcgg
    24901 ccaatcaagg gttgcgtgaa ggattgcagg atgctttggc aactaaactc cctgaggtag
    24961 aactagtgat tccccctctt cgactttgtg gagataatgc tgcaatgatt ggagcagcag
    25021 cacatgtgga aatgcaaaaa agaaattttg ctagctatca gttgaatgct gatccaagct
    25081 tggttttatc tgaataaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
    25141 cccaggaaaa acggcttctc atgtttttga cctggctgtt cttattaccg cgtatgcaag
    25201 cttttgaacg ccgtttaatc aagagttcgt aagcctgtcg tttaactctg attcacaagg
    25261 aacaatttca aaaaacagct cctcatgttt atgaacatta tgacttgtga ccgaagagtt
    25321 gacaggtaca caccgtttaa tcgaaatagg gctgtgacac gtttttgtca aagccctatt
    25381 ttttacatac ttttaatcat tattgttatt ttgctatttt ttacagctta tttatcatta
    25441 tccgttcctc tgattgccct cactgagtaa tcgtttattg tcgaggaata tcgaataatc
    25501 tagatcggat gaggacaaga cgcttcatct agttaatcta acagtatttt ttgcaaacag
    25561 tgaatattac ataactgaaa cacacataga aaatctttga gtcttgtcca gtgatctaaa
    25621 actgccggat ctttcagaag ttttagggag gaaaataagc agtgaccctg atatttatca
    25681 gggtcactgc ttatttttgt tcgcgttatt ctctcatagc tggagtagta gctgtcttac
    25741 agaaagtaaa acgctttttg tcataatcta acagcccgga atcacgtagt tgtttgatta
    25801 cttgtccagc agtttcacgt gtcgtgccgc tattcactgc taattctttt aaggtgatcg
    25861 gataaggaat ggtgatatga ccatcttttg ttggtacgcc caattcttct ttcaaaatga
    25921 ataaattttg ttttacccgg tcaaaggcgc tagaggtcaa tccgatttgg atacgcaatt
    25981 catgtatttc aactacttta gaaatttttt gtatcatata gatcaactgt tcgggatttt
    26041 ttcgtgctaa tttttcatag taggaaacag gaaggtagaa tgtttcaata tcagtcatcg
    26101 cttgagctgt ataagtgtag gtctcttctc caaacattcc tgacatagga aaaaggttat
    26161 ttgtattcac atagtcatag tagtaataag ttgcactttc atcataacgt tctaaacgaa
    26221 cgagtccttt ggtcaagata tacaaccgtt gtctgggatc accatcgtcg aaaaggatct
    26281 gtcctttttt ataagaacga agaacagtat gttccttgat ctgttggaac tcttcatccg
    26341 agaaatgttc aaaatcaggt tgatatctga gttttgaaaa gtgaaaatcg attttattaa
    26401 cacgcattaa aaagtcctct ccttattgtt cactatattt attgtcactt tttttaaaga
    26461 atttgtaaag ttttaacata ccaacattag aaacaagttt taatacttta caaatataat
    26521 ttgttattat gtaaaaaata tacaatggta ttgaataatt tgttttgaag cgaatgattt
    26581 gtgtataaaa aacaacaata atacatatag taaacgctaa caacgataat ataatttatt
    26641 tttttaattt attcaaaaaa attttttcaa tgaataaata tttttttgaa agtgtataca
    26701 gaataaaaaa tgaataaatt acgcttaaaa atagaaaaac gtttaattat ttaattatcg
    26761 aatattaatg tgaggaatgt ctcattttga atgagacaaa attatgaaag tgattacaaa
    26821 aggaggatat cctatacatg taatcaaaaa gaaggaggca acacaacatg gataaaccta
    26881 ttcacgtttt ctctgaaata gggaaattaa agacagtttt actgaaacgg cctggacaag
    26941 aagtggaaaa tttgacacca gatattatgg atcgtctgtt gttcgatgat attccatatc
    27001 ttccgattgc tcaagaagaa catgacaact ttgcgaagac attgcaaaat gaaggcgtcg
    27061 agactcttta cttggaaaaa ttagcggcag aagcgattga cgcaggcaat gtcaaagaac
    27121 aattcttgaa taaaatgttg gatgaatctc atattgcatc gaatgctgta agagagggtc
    27181 ttcatgagtt ccttctatca atggaaacgc aagaaatggt agataaaatc atggctgggg
    27241 ttcgtacaaa agatatcgaa gtacgttcta gcagtctata tgatctgtca gcagacgatg
    27301 actatccatt ttacatggac ccaatgccaa acttgtactt tacacgcgac ccttccgcat
    27361 caatgggaaa tgggatgaca gtcaataaga tgacttttga agcacgtcgt cgtgaatcga
    27421 tgtttacaga atatattttg aaacatcatc caagatttgc aaataaagga atcgaagtat
    27481 ggttggatcg tgaaaatcca gatcatatcg aaggcggaga cgaattgatc ttaagcgata
    27541 aagtagtagc tgttgggatt tctcaacgaa ctaatgcgaa agctttagaa aaattagcac
    27601 gccacctatt cgcaaaaaat tcaggatttg aaaaagtgtt ggcaatcaaa attccgaaca
    27661 accgtgcaat gatgcatttg gataccgtat ttacaatggt agatcacgat aaattcacta
    27721 tccatccagc aattcaaagt aaagacggta agatggatgt ctttacaatc gaaccagatg
    27781 gtgatgatat caagattact cattcagata acttacacga aacgatgaaa gctgctcttg
    27841 gattagatga tcttgtactg atcccaactg gtaatggaga tgagatcgtt gcacctcgag
    27901 aacaatggaa tgatggatca aacacattgg caatcgctcc aggtgttgta gtcacttata
    27961 accgaaatta tgtatcgaac gaattgcttc gtagctatgg catcaaagtg ttagaaatca
    28021 attcaagtga attgtcacga ggtcgtggtg gtccacgctg catgagccaa ccacttgtcc
    28081 gtgaagactt gaagtaattt gtttcctgac ggcagtctta ctgtcagctg ccgtcgggat
    28141 ttcctcttta atcttaaata aaaacaatct aaaggagaat gtttaatatg aaagaatcag
    28201 tattccaagg aagaagctta ttagcagaaa aagactttac aaaagaagaa ttacaatatt
    28261 tgatcgattt ttcagaacac ttgaaagact tgaaaaaacg tggtatccca catcactatc
    28321 tagaaggaaa aaatattgcg cttttatttg aaaaaacatc tacacgtact cgttctgcat
    28381 ttactactgc agcgatcgat ctaggtgcac atcctgaata tctaggtgca aatgatatcc
    28441 aattaggtaa aaaagaatcc acagaagata cagctaaagt actaggacgt atgtttgacg
    28501 gaatcgaatt ccgtggattc agtcaaaaaa tggtagagga actagcagaa ttctctggtg
    28561 ttccagtttg gaatggcttg actgatgaat ggcatccaac acaaatgatc gctgactttt
    28621 taactatcca agaaaacttt ggaacagtag aaggtatcac tgttgcttac tgcggagatg
    28681 gtcgaaacaa tatggctaac tctttattag tcacaggtgc aattttagga gcgaatatgc
    28741 gtatcgttgc accaaaagaa ttacaacctg aagaagaaat cgtcaaaatg gcagaaggct
    28801 ttgctgaaaa atccggtgca caattgatga ttaccgacga tgttgataaa ggtgtagacg
    28861 gagcagacgt cctttattct gatgtatggg tatcaatggg tgaagaagat aaattcgaag
    28921 aacgtatcaa attgttgaaa ccttaccaaa tcaatatgga aatggtagaa aaaacacaca
    28981 acacagatcg tttgatcttc ttgcactgct tgccagcttt ccatgataca aacactgttt
    29041 acggtgaaca aatgaaagaa cgctttggca tcactgaaat ggaagtaaca gatgaagtct
    29101 tccgcagcaa atatgctcgt caatttgacc aagcagaaaa tcgtatgcac tcaatcaaag
    29161 cgatcatggc agcaacatta ggtaacttgt ttatccctcg cgtttaagca taaccacatt
    29221 catctcacga aaaaacgagt cagcattgag ggaaaatcac aaaacgctgg ctcgttttgt
    29281 tatctagaaa attcggtaga actgaagaaa ggacgaatga aatggccaaa cgaaaagtag
    29341 ttgtcgcttt agggggcaat gccatcttgt ctacggatgc aagtgcaaaa gcccaacaag
    29401 aagcgttaat ggaaacagca aagtatttag tgaaatttat cgaacaagga gatgaattga
    29461 tcatctccca cggaaatggt ccgcaagtcg gtaacctatt gattcagcag caagctgctg
    29521 attctgagaa aacaccggca atgcctttag atacatgtgt tgcaatgaca gaaggatcta
    29581 tcggttactg gttacaaaac gccatgggcg aagtactgaa ggaaaaaggg atcgataaag
    29641 atgtggtttc tttagtcact caagttattg tggatgaaaa tgatccttca ttcaaaaatc
    29701 caagtaaacc agtcggtcca ttctacacgg aagaagaagc caaagaacaa atgaatgctg
    29761 actccactgt gacattcaaa gaagatgctg gacgtggatg gagaaaagta gtcgcttccc
    29821 ctaaacccat ctcgattaaa gaagcacgtg tcatcgaaac gctggtcgat caaggagtta
    29881 tcacagtctc tgttggtggc ggtgggattc ctgttgtaga aacagctact ggattagaag
    29941 gacgagaagc cgtaatcgat aaagattttg cttcagaaaa attagccgaa atcatcgatg
    30001 cggatttgct gatcgtattg acaggagtag acaatgtgta tgtcaattac caaaaaccag
    30061 atcaaaagaa attagaaact gttactgttt cagaaatgaa acaatacatt gatgaaaagc
    30121 aattcgctcc aggaagcatg cttccgaaag tagaagcagc tattgcattt gttgaagcaa
    30181 aaccaaacgc taaggcaatc atcacttctt tagaaaatat cgagaatctt ttagcttctg
    30241 aagaaggaac gattatcgta gctgattaat ttgttaagtc tttcgtattt acgaaatgat
    30301 ttatagctat ccaggtggta tttcttctcc tttaggccat ctggatttt
//
LOCUS       DARPZJ010000029        29154 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.030, whole genome shotgun sequence.
ACCESSION   DARPZJ010000029 DARPZJ010000000
VERSION     DARPZJ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.030"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..1030)
                     /locus_tag="SLE23_001601"
     CDS             complement(<1..1030)
                     /locus_tag="SLE23_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8468507.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="SLE23_001602"
     CDS             complement(1112..1801)
                     /locus_tag="SLE23_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEI8468508.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="SLE23_001603"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="SLE23_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEI8468509.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="SLE23_001604"
     CDS             complement(2328..2831)
                     /locus_tag="SLE23_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEI8468510.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="SLE23_001605"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="SLE23_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEI8468511.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="SLE23_001606"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="SLE23_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEI8468512.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="SLE23_001607"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="SLE23_001607"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEI8468513.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="SLE23_001608"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="SLE23_001608"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEI8468514.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="SLE23_001609"
     CDS             complement(6443..7462)
                     /locus_tag="SLE23_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEI8468515.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="SLE23_001610"
     CDS             complement(7635..8540)
                     /locus_tag="SLE23_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8468516.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="SLE23_001611"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="SLE23_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEI8468517.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="SLE23_001612"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="SLE23_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEI8468518.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="SLE23_001613"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="SLE23_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEI8468519.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="SLE23_001614"
     CDS             9753..10397
                     /locus_tag="SLE23_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8468520.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="SLE23_001615"
     CDS             complement(10453..10956)
                     /locus_tag="SLE23_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEI8468521.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="SLE23_001616"
     CDS             11553..12518
                     /locus_tag="SLE23_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEI8468522.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="SLE23_001617"
     CDS             complement(12617..13789)
                     /locus_tag="SLE23_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468523.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="SLE23_001618"
     CDS             complement(13776..14921)
                     /locus_tag="SLE23_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468524.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="SLE23_001619"
     CDS             complement(14935..15867)
                     /locus_tag="SLE23_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468525.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="SLE23_001620"
     CDS             15984..17063
                     /locus_tag="SLE23_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEI8468526.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="SLE23_001621"
     CDS             17060..17689
                     /locus_tag="SLE23_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8468527.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="SLE23_001622"
     CDS             complement(17799..18026)
                     /locus_tag="SLE23_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8468528.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="SLE23_001623"
     CDS             complement(18129..20717)
                     /locus_tag="SLE23_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEI8468529.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="SLE23_001624"
     CDS             complement(20737..21396)
                     /locus_tag="SLE23_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8468530.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="SLE23_001625"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="SLE23_001625"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEI8468531.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="SLE23_001626"
     CDS             complement(22169..23035)
                     /locus_tag="SLE23_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8468532.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="SLE23_001627"
     CDS             23144..23785
                     /locus_tag="SLE23_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEI8468533.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="SLE23_001628"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="SLE23_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HEI8468534.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="SLE23_001629"
     CDS             complement(25226..26125)
                     /locus_tag="SLE23_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEI8468535.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="SLE23_001630"
     CDS             complement(26127..26924)
                     /locus_tag="SLE23_001630"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEI8468536.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="SLE23_001631"
     CDS             complement(26902..27606)
                     /locus_tag="SLE23_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEI8468537.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="SLE23_001632"
     CDS             27737..28312
                     /locus_tag="SLE23_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEI8468538.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="SLE23_001633"
     CDS             28430..29107
                     /locus_tag="SLE23_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEI8468539.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8583 a         6172 c         5242 g         9157 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg taagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaaa aggctctttg tcaaatgatg ttggtaaaga gaaatcttag aata
//
LOCUS       DARPZJ010000030        28828 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.031, whole genome shotgun sequence.
ACCESSION   DARPZJ010000030 DARPZJ010000000
VERSION     DARPZJ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.031"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(43..681)
                     /gene="plsY"
                     /locus_tag="SLE23_001634"
     CDS             complement(43..681)
                     /gene="plsY"
                     /locus_tag="SLE23_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEI8468540.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            808..1242
                     /locus_tag="SLE23_001635"
     CDS             808..1242
                     /locus_tag="SLE23_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEI8468541.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1408..3453
                     /gene="parE"
                     /locus_tag="SLE23_001636"
     CDS             1408..3453
                     /gene="parE"
                     /locus_tag="SLE23_001636"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEI8468542.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3465..5915
                     /gene="parC"
                     /locus_tag="SLE23_001637"
     CDS             3465..5915
                     /gene="parC"
                     /locus_tag="SLE23_001637"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEI8468543.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6192..8423
                     /gene="pflB"
                     /locus_tag="SLE23_001638"
     CDS             6192..8423
                     /gene="pflB"
                     /locus_tag="SLE23_001638"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEI8468544.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8667..9428
                     /gene="pflA"
                     /locus_tag="SLE23_001639"
     CDS             8667..9428
                     /gene="pflA"
                     /locus_tag="SLE23_001639"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEI8468545.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9513..10439
                     /locus_tag="SLE23_001640"
     CDS             9513..10439
                     /locus_tag="SLE23_001640"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEI8468546.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10621..11514
                     /locus_tag="SLE23_001641"
     CDS             10621..11514
                     /locus_tag="SLE23_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEI8468547.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11648..11773
                     /locus_tag="SLE23_001642"
     CDS             11648..11773
                     /locus_tag="SLE23_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8468548.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11907..12539)
                     /locus_tag="SLE23_001643"
     CDS             complement(11907..12539)
                     /locus_tag="SLE23_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468549.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12687..13229)
                     /locus_tag="SLE23_001644"
     CDS             complement(12687..13229)
                     /locus_tag="SLE23_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HEI8468550.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13364..13753
                     /locus_tag="SLE23_001645"
     CDS             13364..13753
                     /locus_tag="SLE23_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468551.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13757..14521
                     /locus_tag="SLE23_001646"
     CDS             13757..14521
                     /locus_tag="SLE23_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8468552.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQAGEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14650..15597
                     /locus_tag="SLE23_001647"
     CDS             14650..15597
                     /locus_tag="SLE23_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8468553.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15727..16467
                     /locus_tag="SLE23_001648"
     CDS             15727..16467
                     /locus_tag="SLE23_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468554.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16758..17426)
                     /locus_tag="SLE23_001649"
     CDS             complement(16758..17426)
                     /locus_tag="SLE23_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8468555.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17560..17847
                     /locus_tag="SLE23_001650"
     CDS             17560..17847
                     /locus_tag="SLE23_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468556.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18263..19801
                     /locus_tag="SLE23_001651"
     CDS             18263..19801
                     /locus_tag="SLE23_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEI8468557.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYRELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19798..20763
                     /locus_tag="SLE23_001652"
     CDS             19798..20763
                     /locus_tag="SLE23_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468558.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20750..22072
                     /locus_tag="SLE23_001653"
     CDS             20750..22072
                     /locus_tag="SLE23_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8468559.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22135..22239
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22313..23056
                     /locus_tag="SLE23_001654"
     CDS             22313..23056
                     /locus_tag="SLE23_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468560.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23071..24063
                     /locus_tag="SLE23_001655"
     CDS             23071..24063
                     /locus_tag="SLE23_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8468561.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24075..24812
                     /locus_tag="SLE23_001656"
     CDS             24075..24812
                     /locus_tag="SLE23_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468562.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24802..25524
                     /locus_tag="SLE23_001657"
     CDS             24802..25524
                     /locus_tag="SLE23_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEI8468563.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25608..26231)
                     /locus_tag="SLE23_001658"
     CDS             complement(25608..26231)
                     /locus_tag="SLE23_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8468564.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            26626..27317
                     /locus_tag="SLE23_001659"
                     /pseudo
     CDS             26626..27317
                     /locus_tag="SLE23_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            27525..27815
                     /locus_tag="SLE23_001660"
     CDS             27525..27815
                     /locus_tag="SLE23_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468565.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT        10003 a         4824 c         5951 g         8050 t
ORIGIN      
        1 atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt ttttcttgct
       61 gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct tgatattgtc
      121 tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca gtaaccaatt
      181 gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata aagtgatcaa
      241 tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac taacgataaa
      301 gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc ctgcacttgt
      361 cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc caagaatggc
      421 gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt
      481 agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg ttttgcctaa
      541 tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga tatctttttt
      601 gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat atgctaaaat
      661 aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat cctttatttt
      721 agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata atagatggaa
      781 taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt
      841 ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa
      901 cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat cataccagta
      961 aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa tttgacagaa
     1021 atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt acctgaaata
     1081 gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg gattgaaaac
     1141 aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat ggatcgttgt
     1201 attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga
     1261 gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa ttgatttctc
     1321 gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc ggttttgccg
     1381 caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga atacaatgac
     1441 tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg gatgtacatt
     1501 ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga taatgcagtt
     1561 gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga agacaatagt
     1621 ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc cggaatacca
     1681 acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca aggagggtac
     1741 aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg
     1801 ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa aaacggcggt
     1861 aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc
     1921 cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga aattttagcc
     1981 gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct ttctgatctt
     2041 cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa agaatttgtt
     2101 gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc aggagaaaaa
     2161 gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga aaatgtttta
     2221 tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg tatgaaagcg
     2281 gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa agaacgggac
     2341 aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc tatccgtgta
     2401 cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac gccagttgct
     2461 cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca ggaaaatagc
     2521 gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag agaagcagca
     2581 cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga atctcttctt
     2641 tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt gtatttagtc
     2701 gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt ccaagcaatt
     2761 ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa
     2821 aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc tgagttttct
     2881 atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac agacggcgcc
     2941 catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct gattgaagct
     3001 gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca aggaaagaag
     3061 caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa aaaagtcggc
     3121 aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga acaattgtgg
     3181 gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg
     3241 caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg aagaaaatgg
     3301 atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga taaaaaagag
     3361 gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg agcagataaa
     3421 aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa aatcgacaag
     3481 aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt tattccaaat
     3541 atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc
     3601 ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc cgtaaatcag
     3661 caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgaccgc agtatttatg
     3721 aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc gaaatgcacg
     3781 ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact gaagccagat
     3841 tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc gatctcgtgt
     3901 ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac ccaaaccttc
     3961 tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg actcataact
     4021 tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg agccttgaaa
     4081 aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg caaggaaaag
     4141 atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa
     4201 agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc ccatatgaag
     4261 taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag aaaatcgatg
     4321 gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc gtcgaattga
     4381 aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact gagctacaga
     4441 tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa gttggactga
     4501 aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat
     4561 tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg aaagctttat
     4621 cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa
     4681 agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt gtcacattgc
     4741 aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc gaaagcttga
     4801 ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt ttctctgtta
     4861 tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg
     4921 aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa gaagacgtaa
     4981 ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct tatagtgctt
     5041 ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca ggtgaattga
     5101 gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc
     5161 atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa acaatctcca
     5221 atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt caagcagaga
     5281 aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg acagagttcg
     5341 aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag gcggaagaag
     5401 atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt ttcttagtaa
     5461 cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt ggagcaaagg
     5521 cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac gggctgcttg
     5581 tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct gttaaacgca
     5641 tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg
     5701 agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca aaagaaataa
     5761 ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc cctataggtg
     5821 atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag
     5881 ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga
     5941 cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata aatccttata
     6001 cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat
     6061 ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa
     6121 agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg
     6181 aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag
     6241 acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg
     6301 aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc
     6361 aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac
     6421 acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac
     6481 ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa
     6541 gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac
     6601 ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa
     6661 tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg
     6721 tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg
     6781 gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc
     6841 gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag
     6901 ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat
     6961 cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc
     7021 aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact
     7081 tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct
     7141 caggattccc tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat
     7201 tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag
     7261 aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga acatatgcta
     7321 gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac
     7381 aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag
     7441 acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg
     7501 gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag
     7561 aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag
     7621 aactatatgt caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag
     7681 cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg
     7741 ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc
     7801 gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa
     7861 atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa
     7921 tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt
     7981 caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac
     8041 cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc
     8101 tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa
     8161 caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg
     8221 tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg
     8281 atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat
     8341 ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga
     8401 gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa
     8461 aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt tgaaagaaac
     8521 gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg
     8581 caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg
     8641 aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta
     8701 tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat
     8761 gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag
     8821 aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata
     8881 aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac
     8941 tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt
     9001 ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac
     9061 tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca
     9121 atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc
     9181 gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact
     9241 ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa
     9301 aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa
     9361 aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa
     9421 cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat
     9481 taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc
     9541 aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat
     9601 taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat
     9661 tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag
     9721 atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa
     9781 atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt
     9841 actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa
     9901 accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata
     9961 cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg
    10021 cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa
    10081 atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg
    10141 gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc
    10201 gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt
    10261 tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag
    10321 gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta
    10381 aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat
    10441 caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat
    10501 agaacatact aaaggccgaa gaaatggagg agaataacag tcaattatga ctcttgttct
    10561 tcctcctttt tacgtaaaag ccttttaagt aaaataaaac ggatagaaaa gagaacatat
    10621 atgaactatt attcaaaaaa taaggaaaac ttttatcaaa aactgaccga tgatccgctt
    10681 ttttcttcat tgaccgatta tctatatgaa catcgagaac aagaaacgat tctaagagaa
    10741 ttgaaaaaag aattttcgca aaataaattt tcccattttc ttgatttatt gatcgatgca
    10801 ggattaatca agagggaaga acgaagatat catttgaact ttccaatatt tgatcctaaa
    10861 gattacttgc aacaagccac ttcggctgct gaaaccatag ctgaacaatt gaagagactc
    10921 tctgttgatg aacaaaaatt agcgatggga gaagttattt gggcgtattg tttcgaagat
    10981 gaacggaaag aagcgtattt ttatggagta agaaacagcc gagagacaga attgctgagg
    11041 acaactgcag gaaatgagaa gtaccgtttt atcacacttt cctctataga acacttcccg
    11101 cttactttgg ctaattactt ttttgtacag aagaatcagc ttcctgtaac gaaggcattc
    11161 aaagaattag ccgaacttat tggagacgta aatgaatcgt acttttttga tcaaatagaa
    11221 gttatcgttg acaggatacg taagaataaa tataaaaatc gccggcctag tattttccat
    11281 cagtctctac ttgtgacgaa tactataaag gaagaagaat cattcacatt agaattacct
    11341 attgtcgaaa aaaacaattt tgagattgaa ttaccaacat tggatccttc attgacaatg
    11401 gaggaaatgg cctttcttaa acgacaaatc ttttctgagc tgagcaagaa atttataccg
    11461 catgcatttt cttatatcaa agaatatgga acagttttag tgagtaaaac ctaagagagc
    11521 agtaagcaaa aattatactg actcttgcag gaggagcctt tctcttcctt tatggttaaa
    11581 agaattattt gagtattttg cctatctacc acctattaga ttcactacat ggtctggaaa
    11641 caaaggaatg caaaaaaatg gtgagaaatg tggaatgaca aaggaagtag tgataagaaa
    11701 agttagattt ttaaataatc aatattatga ttcagtcaag tatggcattt tatgggaaga
    11761 actagctgat tagattagga agtccatttg ataatccaga atcactaaga aacgaatggc
    11821 gagtcattaa taatttatcc aatcttgggt tattctttta gattgaagtg tttaaaacta
    11881 aaaaagcatt tatgaagtcg taatagtcag gcttcaaaat gctttttatt ttgtttgttt
    11941 tttctttgcc acataaatac acctagactg acgatgaaga gcatatccaa cagatttcct
    12001 gcgacttgga tcgtcgaagg gttggtcagt ggcattaaag caaggacaaa aaaggaaaac
    12061 aagctgtaaa taaaacaggt gacaggaact aatcgaaaga agagcggaca tttcaattgg
    12121 ctaaaaatga gtgaaaaaat aaaataagta aaaatggata aaatcacgac taaaccattc
    12181 atgataaaga agaaaagcgt attgtgatta aacgaataaa aaagaattgc taaaaaagaa
    12241 aacgttttaa atgcaatcaa tacgcttgaa gcttcgttta acgtaccagg atgtcgatga
    12301 aaaaaatagg caccgaaata aacagaaaac agtaagccgc aaagagaaga caaaatcaaa
    12361 aaaaacggat tttcttcggc ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat
    12421 gcactagaag gcgcatgtga ggtcttaagg tatgaataac atagaaaaaa taagatcgtc
    12481 aaagttgcaa aaaaagagcc taaatgtaaa aaattagtgg ttctacgttg aatttccata
    12541 atatctccaa attaaattga taagtatata aagtataata acaaattgat gagtatatgt
    12601 cgatgttttt taatcaaaat aataaataaa aactgtctaa catttaaaat ttaatttaga
    12661 tattagacag tttttaagtt tgtgagttat tttccttgtc gttttctcac ttttttagtc
    12721 cagaaaccac ctgaaatata ttttggctca taagaaatga taaaagcacg ctcttcgatt
    12781 tctttgatca ggcgatacag ttcacgttcg ctttttctag gagaaagtat ttcgagaact
    12841 agccgctcac cttccagccc cattgcagaa gtctgtgtca caccataacc gtgttctctc
    12901 agtatacccg gcaaactttt atcttctgcg ctatttgctg gcaaaatcgt tgtgaccatg
    12961 atgtatccta atgccaattt gtcttcaatc aaaattccga cactgatacc tactgcgtaa
    13021 cctaacgcat agacaaataa attcagtgga ttatctaaac gatctaaaac aagggataag
    13081 ccgacgatat aaatcgtgat ctcgaccata ctgacaagtg gagcaatcag tcgatagcct
    13141 ttcattgtca acatgaaacg taacgtgttc agagtgatat aagcaaaatt aatgaggaag
    13201 atcatcccca acatttttgg atcaatcatt tgtaaaactc ctttcattta tataacaaca
    13261 atatcaaaaa aaatcgtaag tgaagaaaaa ttgaaacttt atacatacaa aaaaatgata
    13321 aaatgattat aatagaatta taaagatagg ttaggtgatt aaaatgaaaa cggtcaatcg
    13381 tgtgttttgt gccagccacg tgctaagtct ccttctcagt atatacttag gtgtctattc
    13441 gattcaacag ccaattgagg tagagaacat tgtttttcag atgtcgctga cagatggttt
    13501 aattttaagc gtttttttct ttttgatact gtttattggt aatattttcg gtagcgttgc
    13561 cagttttttg aatttttcta tttatccact cctttcgcta gcattaggag tggtgggact
    13621 ttgttctctg tgcttatttc ccgagccatt cagtcctgca tttatattat ttggtacact
    13681 gaacctgttc cagacaactg ttggagcatg gttgctatgg cgatcaggaa atttaatgaa
    13741 aataggtgag taacaattga atccaattat attgaaacgt tctgtccatc atattccagt
    13801 gttagaagtt gttctgaaag aattaagaga ggaacgtatt cccgttgtca tctattatca
    13861 cggatggcag acaagtaagg agttagtttt gacgcaagga agaaaaattg cgcagcaggg
    13921 cattcgtgtg atcctgccag atgcgatgaa tcatggggag cgcaaacagc cggtttcttc
    13981 tattccatcc tatacatttt gggatagtat ctacggaaat ctgtttgaat ttgacacact
    14041 tatcaagcat ttagaaaaaa gaggtcttct acatgatcag cttgcagttg gcggggtttc
    14101 gatgggggga atgacaacat gcgccttgtt ggctaaacat cctcatatag tagcgggcgt
    14161 gtgtttgatg ggttcccctg cacctttgga atatggaaaa gaaatcgtaa ggcgcgcatc
    14221 ggaatataat tatgtcgtac caaaagacta ttttgatttg atttcatggg ttaagagcta
    14281 tgatttgtca ttgcagccgg aaaagttagc tggacgtcct ctgttctttt ggcatggaca
    14341 agctggcgaa aaaatccctt atatacaaac ggaacgattt gtagaaaaaa atcggcataa
    14401 gtcttacgga aaagaaattg tttttcgttc ctcaaaaaca cagcgacata tggtacaaat
    14461 accactaatg gaagaagctt ccactttttt agcaaaaaat ttgataaaaa agtataaata
    14521 attgaaacgg aaaatcactc atgacgatag aggattttcc gttttttatt ttgggctata
    14581 ataaactctg ttaggaaaat ttggtataat tgatagtaag aatgacaaca tgttagaaag
    14641 gaagagagca tgcccacttt agcagatgtt gcaaaacgtg ccaatgtttc aaaaatgacg
    14701 gtctctcgag tcatcaatca tccggaacag gtgactgacg aattgaaaga gttagttttc
    14761 tcagcaatgg ctgaactgga ttaccgtcca aatattgctg caaaagcact tgtcacgaat
    14821 cggtcgcaga tcatcaaatt atttatactg gaagaaatcg acacaactga gccctattac
    14881 atgaatttgc tgatgggaat cgctaaacgg atcggtaaag cgcattattc tctccaatta
    14941 gttacaaatg atgccttcga cgtcggttct tgtgatggat acatcatcac aggtgtcaga
    15001 aaaaaagact tcgattggat cgaccgtttg gaaaaaccag ttgtcttgtt tggggaaaat
    15061 tctgaaggat atgattatgt agacagcgat aatgaatatg gtacagcaaa agcaacgcaa
    15121 tatgccttag aaagagatta tcaaacgatt atttatatcg gtatcgaagt ggacgagcct
    15181 tttgaaattt caagggaaac tggttattta tctgtgatga aggaagttga tcttcctagt
    15241 aaaatcttgc ggtttccaaa tcattcgaca gaagtagaaa gatatatgac agaaaactgg
    15301 gcagatttta cagataaaac ttgttttgta tgtagttcag atcggctagc actaggagca
    15361 gtaagaggga ttataaatgc tggaggacac ttgcccgaag aatttggtgt gattggattt
    15421 gatggggtat ttttagacca aatcagttca cctaaattga caacgatcaa gcaagatatt
    15481 atacgtatgg gtgaagtatg tggagaaatg ttgttaaaaa aaatagaaga aaaaggggcg
    15541 agtcaaggtt atcgtcgttt ttttcctgaa ctagttatca gagagacaac gaattaagtc
    15601 ttattactat atatatattt atgaaattca tcgctatttt cttaaaataa tcagcgcatt
    15661 gctactgaaa acaatgaatc tgtgctatta ttgagaaaag ttccattttt gagaaggatg
    15721 gtttgaatga aagaaatcag acgaaaacat ttccgttttc ctgcgtacga tgatgagtta
    15781 ggcgtaaaat taaccaacga caagaagcga gtattatttg acggacaaga agatcttttg
    15841 actgaacaga atcagtcccc gtttgaacag atgaaagaat ttcatttcac gaacacgaac
    15901 accgagaaaa tccgtcgcaa gcgtcgtgca acaaatggat tgaagtcagc tccgcgtaag
    15961 gaaaatttgg aaaagcataa aggaaaatta ccggattata ccggccatta ccaatcagaa
    16021 atcacatcga caggacgaaa aaaacttttt ggtgattcct ctcgttctgt cagacaaagt
    16081 gaaacaagga cagagtccaa gcatactaca cgaaacgcat ctgttgacac gaaggtgcgg
    16141 gagcgttctt attttgttcc taaatatgta cccgcatcga ttatcccaga ccctagagaa
    16201 agcaaaattt ctgaggatca tttaatcgaa tcgatgaaaa aaacggatga ctcttatctg
    16261 ttgttcgata cagaaccgac gccgtatcaa gaaaaaagaa atggtgagcc gtctgtacga
    16321 acattcaatc gaacaaaaac gttagaggaa acaaagcagt cagaagaaaa aaaatcgaaa
    16381 aaaagccatg gtatcttaga acgctcatta caaggattga tcgatgatca aggaaactct
    16441 ttgggagaaa atagctattt taaataagtg atatacaaat ttatattcgg ctacagttgg
    16501 aaaggaaacg ctgcggcgtt tccttatttt atactctatc cgaaagttta tatcgtatcc
    16561 tcaaattttt ttgagtttaa gcgaattttt tctcccaata agtaagaaaa taatggcaaa
    16621 ataaaaaaac aaactatttt cgcagatcgt ttgcaaaaat agtttatttt tttataaaga
    16681 agattttact gaataatatc attttagttt acataatgat atttctgtaa attaaataaa
    16741 gtagtgaaaa ataagaatca gtgctctaac tgttcaagag gatcaagtgg ttcaaatgtt
    16801 tctgtagtct gttttgcttc caattggggc aaaacagatc caatttccag atacttcact
    16861 ttattcaatg tataagatag aatagaacag ctaagtaatg tatacagaaa atgtgtgaga
    16921 tccaaataaa gcaaggagac aactaaaata ccaaaagtaa tcaagaaaag acttttgcca
    16981 atcttaatat gaaaatattt ttcaatggct tgataaatga tatctgttcc gcctgtgctt
    17041 ccgccgaatc gaaagacgag accgcaacca atgccagaaa gaatacctgt catcaaacta
    17101 ttgatcagta gactatctac agcaaaatgt atatgaaggc tctcccataa atgtaaaaag
    17161 aaaactagcg caaatgttcc gacgatcgtc cggagaaaag cgtgttttcc aaaaagaaac
    17221 aatgagataa gcaataaagg taaattaaaa agcagtgaag tgacagaagg agcgaatcca
    17281 aaaagattat gcaaaagcaa agcaatacca gtaaccccac catctgccag cttagatgga
    17341 atattgattc ctgtcacagc taatccgtag attcctgcgc ctaaaatgat tccgcacaat
    17401 tctgtaaata aatttaattt tttcatttct agcctctttt cttttgaaaa ttttcagcaa
    17461 cttctttatt atactgactt atactcttac ttcaagagga aaatgaaaaa aaattatttt
    17521 tggctgtttc tttttattta tcaaataagg agtggaaaaa tgcgagcagc agacttattg
    17581 acaattctta caaaatcacc caaaaaaaca gagtatcaag gagttttttt ggctcaagaa
    17641 caaaaactgg tgcctgtgac aatggtccag ataaataaag caaatcaatt tatcttttta
    17701 tttgaacacg gcaaagcacc acttgctatg aaagacatct ttcttttttt gatgaagaac
    17761 cgtgagaaag ctgtttatta tcagtcaaaa gaagaactca ttcctcttta tggagtgaaa
    17821 gagatagaaa ataaagtggt gatataagta aaaataagaa aacaagacgt ttatgatgtc
    17881 aaaacaacca ttttttacat ttttggcaaa aaagtgtcat gatacagtat aatattcgtt
    17941 gaacaggcca ataaaggtgt tctcccccac gagatttcta ctttattggc tgtttctttt
    18001 tattaaaata aaagttgtgt gtgtaaaaaa gatatagctg attccaagtg acaatttcgt
    18061 atagattttt atggtattcg tagtgaaaaa acgagaacca aaaagttgat ccgactttgt
    18121 tgcttggatt ctttttttgt cagcatattt agaggtattt ttttcttttt tttgttcgtg
    18181 ctgtaaggtt aaggcaagac aagttagttg ggaaaaagga aagaaatgtt tatacttaaa
    18241 gaataacaga aaggaaggtc gcatgaataa ttttatacaa acattaagtg aaagaaaagg
    18301 cgagttgctg gaagctgcat ttcaacatct gtccatttct ctcatttctt tgctgattgc
    18361 agcactgatt gctattcctt tagcgatttg ggcagccaat cataaaaaaa tggcagaagt
    18421 cttattgcag atcacgggtg tgctccaaac gattccttca cttgccttat taggtttact
    18481 tatcccattt gtagggatcg gaactgttcc agcattgatt gcacttgtta tttacgcttt
    18541 gcttccgatt ttccaaaaca cgtatattgg tctagctgaa attgacccgt ctattgaaga
    18601 agcagcggta gcatttggta tgtccagaat gagacgcttg ctgaaagtag agcttcccat
    18661 cgcattacct gtcattatct caggtatccg aactgcctta gttttaatca tcggtacggc
    18721 tactttggca gcattgatcg gagcaggtgg attagggaca tttattttgt taggtattga
    18781 ccgaaataca cctgttttga cattgattgg tgcgatcagt tctgccttgc ttgcaattat
    18841 attcagcgga ctgattcgct ggttgcagca taagaaacct cgatattcca tcattacttt
    18901 agcagcagtg gtgtgtttat ttggcggcgt ttctttatat cagtctgcct tgtttaaaaa
    18961 tgaaaccatc acgattgctg gaaaattagg agcggaacct gaaatcctga tccaaatgta
    19021 tagagaattg attgaagaca acacaaaaac agaagttgaa ttaaaaccga attttggcaa
    19081 gacgagtttt ttgttcaatg cactggatca aggtcaaatc gatatctatc ctgagttcac
    19141 aggtactgtc ctagaaagct tggtgaaggt acctgaagca atgaaaagtg ctgatttgac
    19201 aaaagaaaaa acatatgacg aagcagaaga attattgaat aagcaattcg atatgacatt
    19261 attaaaacca atggcttacc aaaatacgta tgccttggca gtcaagagat cttttgcgaa
    19321 cgaacatcaa cttaaaaaga tttccgattt ggcagctatc tctgatcaga tcaaagcggg
    19381 attcacactg gaatttattg atcgttcaga tggatataaa ggaatccaag aagcatatgg
    19441 cttgaatttt tcaagtgtac aaagcatgga gccaagtttg cgttaccaag caatcaataa
    19501 tggagatgtc aatattgtgg atgcctattc cacagatagc cagctcaagg agtacgatct
    19561 agtgactcta gaagatgatc gagggttatt cccagcttat caaggcgcac cgctgatgaa
    19621 aaaagatttt gctaaagaac atcctgaaat cgttaaagca ctgaataaat taagcggaaa
    19681 aataacagag gatcaaatga ttgatatgaa ttaccaagtc aatgtcgaaa agaaaaagcc
    19741 gacagaagta gcacgaatct tcctgaaaaa tgaaggatta gtaaaggagg aagatcagtg
    19801 actaaattaa tcgagttcaa acatgtgcaa aaaaagtatg atggaaagta tgtcatcgat
    19861 gacctaaatc tggcaatcaa aaaaggagaa atctttgttt tggttggtcc ttccggtagt
    19921 ggaaaaacaa ctactttgaa aatgatcaat ggattatcta aaccatcagc aggagacatc
    19981 tacttcaaag gaaaatcgtt aaatgaatat aatctgcaga aaatgcggtg gaatatggga
    20041 tatgtgctgc agcaaatcgc tttgttcccg accatgacag tcaagcaaaa tattgaagtc
    20101 atccctgaaa tgttaggttg ggaaaagcag aaaagagcag accgtgtaga tgaacttctt
    20161 caaaaagttg gcttatctcc tgatatttat cgagatcgta tgcctagaga gttgtctgga
    20221 ggagaacagc aacggatcgg gatcatccga gctattgctg caagcccaga tgtgattttg
    20281 atggacgagc catttagcgc attagatccg atttcaagaa actcattaca agaattggtt
    20341 ttgtccttac acgaagaatt gggcacgacc atcgttttcg ttacgcacaa tatggaagaa
    20401 gcaatcaagc taggtgatcg tattgcattt atgaaggatg gagaaattat ccaatgtgac
    20461 acaccagagc agttattgat gaatcctaaa aacgactacg ttcggcattt ctttgatgaa
    20521 ccgaaacaga cgaaagagtg gcgagtagaa gatttagtcg tcaatggata tttcttaaat
    20581 gaaataccag aaaatgctcg tcaacaagtt tgctttgata cgcctatgaa agaagtatat
    20641 tcgcttcttt cggtgtatcc aagcattgtg atagtagaaa agcaaagaag tattgggtcg
    20701 ctgacaagta aagaaatctt tgctttttta agtcgagagg aggaaggaaa tgaaaacata
    20761 tgatgcaatc atcatcggtt caggtgtgag cggcttaagt gctgcttatg gattgaaaga
    20821 agcaggtaaa acagtactag tggtcgaaga agatctatgg ggcgggactt gtcctaaccg
    20881 tggatgtgat cctaaaaaag tcttgttaag tgcagtagag gcacgtaatc gggtaaaaca
    20941 attgagtgga aaaggtttta acgagatccc aactgccaac tgggaagaac ttcaaaaatt
    21001 caaacgaaca tttacggatc cagtcccaga aagccgaaaa aaacaattag cagaagctga
    21061 aatcgatcat ctttcaggaa ccgctcgttt tttggatgat tcatctattg aagtcaacga
    21121 agaagtcttc catgcggatt acttagtttt ggcaaccggg caaagaccta cgatcttacc
    21181 agtggaggga aaggaatact tgaaaactag tgcagacttt ttatcattgc ctgtactgcc
    21241 taaagaaatc atttttatcg gtggtggtta tattgctttt gagctagcta cgattgccaa
    21301 tgctgcaggg agcaaagtaa ccattgtcca tcataatcaa cggccattaa aagaatttga
    21361 ggcgtctttg gtagaggaag ccgtccatca aatggaagca tctggcattc agtttgcttt
    21421 tggtgttgaa acccaaaaga tcatttcaga aggtactcgc tatcgtttag tcggaaaaga
    21481 gacggaatta gtagcagata tgattttttg tgcgactggg agacagccga atacagaatc
    21541 tttagcactt gagcaagcga atatcgtctt tgataaacac ggaattgcag tcaatgatta
    21601 tctgcaaacg agcaatccaa aaatttttgc gtgtggagat attgtttcaa ggaaaacccc
    21661 aaaattgaca ccagtcgcca cttttgaagg aaattatgta gctaagcgga taacggatgc
    21721 aacaagcgaa cctatcaaat atccgattat acctacgatc gtctacgcca gtcctaaact
    21781 tgctgaagta ggagttacaa aaagtcacgc ctcttcgtca gatcaagtgg tagagatgga
    21841 tcttaccagt tggttcacct atcatcgtgt caatgaacca gttgctaagg ctgaattgac
    21901 ctttgaccag caaaattatt tgattggtgc tgcagtgatt agcgagcaag cagacgaatt
    21961 gatcgatgat ttgacactcg tcatcaatca aaaattgact aaaaaagagt tggatagcta
    22021 tatcatgggg tatccgacat tggcaagtga tctctcctat ttattgaaat aatcagcatg
    22081 ataactaaag cgcttgttgc tttttccttc ttgtgctaca ctttaaaaaa tgaatacctg
    22141 tttctgggga tgtcgtagac gacatgagag taagttgtga acttagaccc attgaacctg
    22201 tcagttaata ctggtgaagg gagaaacata gcagacgctt gaagcgggtt actatgtcgt
    22261 gcccatttca agcgtttttt gttattcata ttagaagaaa ggaggtaaca aaatgaagaa
    22321 aaatctttat ccagcagtca gtatggcatt cattttaatt atttggcaga ttgttgtcat
    22381 agtttggaaa atacctgcct ttattttacc cggacctgct gctgtatttt ctgcattagc
    22441 ggcagatgca caagtattac tttcccattc tgtcacgaca ttaaatgaag cagtgcttgg
    22501 tttggtaata gctagcgttc tttcttttat tactgccttg gcaatggatt attggaagtt
    22561 tttagaaatg tctttttatc cgttactagt gatttcacaa atgttgccaa tcatggtgtt
    22621 agggccatta cttaccctat ggtttggttt cggtatgctt ccaaaagtga tccttgttgt
    22681 cttgataagc tattttccga tcgtagtttc tttttcggat acattgagga aagtatcaaa
    22741 agagcaaatc atctttttga aaacgatggg ggcagataca gggaagattt atcgaatata
    22801 taaaatacca gcgggtttat ccggcttctt ttccggttta aaagtggctg ctacttattg
    22861 tgtcagcgga gcagtcgttg gagaatggct aagcgctcaa gcaggcttag ggtattacat
    22921 gatacgcgta aaaaacagct accagatcga taaagttttt gctgcgatca tttgtgtcat
    22981 tctattgagt ttattgctga atggcgcttg ttcattattg aaaaaagggt attatcgtat
    23041 gctttatatt ttttaagaga aggggatcaa atgaaaaaat tatggctttt attaccgcta
    23101 ctgttgcttt tatccgcttg tggcactgca aaagaaacaa gtagcaaaca agaaataaag
    23161 gatttgaaaa aagtgacact tgttttggat tatgtaccga atactaatca tactggcatc
    23221 tacctagcaa aagaaaaagg ctattataaa gaggctggtt taaatgtcca aatcatcgaa
    23281 ccaggagata attcgacaag tattggtcta gtaggtgcgg acaaagcaca atttggtgta
    23341 agttatcaag aagatgtcac ttatgctcac gcagatggac agaatatacc agtcaaagca
    23401 attgctacag tgatcaaaca taatacttct ggattcgcca ccctatcaga cagtaacatc
    23461 cattcaccaa aagattttga aggaaaaaca tatgcaggtt ggcaaagtcc aagtgaagaa
    23521 gctgtcttaa aagctgtgat ggaaaaagac ggcggggact tttcaaaact gacaatggta
    23581 ggaagcaatg gagaagggcc agaaagctta ggaaaatcct cagatatcca atggtacttt
    23641 gaaggttggg atatgatcaa agcaaaagaa gcgggtattg aactaaacta tatcccattg
    23701 aaagaattag atgaacggtt agattactat actccggtaa ttattacgaa tgatcaactg
    23761 atcaaaagtg atccagaatt ggtacagtct tttatggatg ccacgaaaaa aggctatcag
    23821 gaagctatta aggatccaaa tgacagtgct aaactgttgc aaaaatatgc aaaagaaaat
    23881 gatcggacgt ttttagaaga atcacaagca ttcttgtcaa aaaattatac ggatgatcct
    23941 gagaattggg gattgatgga agaaaaagtt tggcgcaatt atacagcttt tatgcaggaa
    24001 aacggattga tcaagcaaga tgtaccttcg caagaactat tcactaatca gtttataaaa
    24061 taggagtgat agatatgtca atccaaatca gccacttgaa tgtagtcatt gaaaacctga
    24121 aaatattaga agacatccat ttcactatcc ctaaagatac ctttacatcg attgtcgcgc
    24181 caagcggagc cggtaagtca acattgctga aaactttaac aggagtccag cctatgactt
    24241 ctggaacgat caaagtagac gatcaaaaag taactggtct ccatacagca tttagttata
    24301 tgccgcaaga agatatgtta cttccttggc tgagcgtcta tcaaaacgtt acgttatatc
    24361 aaaaaatcaa tcatctaaca atcaatgaag aacaagtaag ggattatctg gatatctttg
    24421 ggttaaacgg ctatgaacat tttttgccgg aacaattatc tggcgggatg aagcagcgaa
    24481 cggccttgtt acgaacaatc atgaatcctt cttcttactt gcttcttgat gaaccatttg
    24541 gagcgttaga tgctatgacc agagggcaga tgcaagactg gatgttgaag ctgcctaaaa
    24601 aagcaaagcg gactacttta cttgtgacgc atgatatcga agaagcaatt tatttatcag
    24661 acaggattct tgtgctttcc gcccgtccgg cacatgtgat tgctgagatt caagtgcctg
    24721 aaaaacgacg gtcacgtgaa tggctactgc agcaatcaga gttgaagcaa acgatttatc
    24781 agttattggc aggtgaatta gatgttaagt gatgctcatt gtcatttaga tgggagtcag
    24841 agtttagcac tccttcagca ggaacacacg attttgacga tcatcaattg tgattcgcca
    24901 gaagaatgga aggaaaacag acagcttgca gcaagtaaga ctcaagcctt aagttacggt
    24961 atccatcctt ggaaagcaga tagctatacg tttgaacaag ttgagccttt tttgaaaaaa
    25021 gcaaggatca tcggtgaaat agggttagat aatatttgga cgaatgtacc gatgactaca
    25081 caaaaaaaag tatttgagcg acagcttgct tttgcagcca taaatgagaa acctgttgta
    25141 ctgcacacaa aaggatgcga aaaagagatc ttaaattata tccaagctta ccctaatcac
    25201 tatttgatcc attggtattc ttctttggac tatcaacaag actatattga tttaggctgt
    25261 tatttcagca ttggtcttga tttgaaaaag aatccagcag tctggcaact agctaaagca
    25321 gtcccaatcg accacttact tattgaaacg gatggactac atgcagcaga gtgggcttta
    25381 ggggggattt tttcagaaaa agattatgtc tcactgcttg aagaacagtt aaagacaatc
    25441 gctgagatca aagagctatc agttgaagaa gttaaaaaaa atacttatca aaacttggaa
    25501 cgtttcatta gattaggtaa ataaaaaaga gatgtgacac aactagtgtc gcacctcttt
    25561 ttggctttct ttgtataaaa gtaaactgtt tgattaataa atgaatctta gtaccaaccg
    25621 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    25681 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    25741 tggtaacgtc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    25801 gcgatccatt cttttgcaga gcttgtgctt gctggagtag cagcagtttc tgttacagca
    25861 ggagcaggtt gtgtttcagc aacaggcgct gcttgttttt ccgtttgaac cgtttcttgt
    25921 acaacaggtt gttcagcttg gactggtgct tcttgaacgg ctgcttgagg ttcagcagct
    25981 gcttgtgcag agccttctgt tgggattgtt aattgttgtc ctgagtaaat caggttaata
    26041 tcagaaattg aatttgattc tgcaatggca ttgatcaagg agttatcacc aacgtatttt
    26101 tgagaaatcg ttgatagagt atcacctgat tgaacggtat aagcttcgtc cgcatgagca
    26161 gtcgttccca tgaagaatgc agcgccggca gccaaagttg ttccaaaaag taaagtttta
    26221 agtgatgtca tgaaaaatct cctttattcg ttaaaaagtt ttatttgttg tgttcaacga
    26281 ggaatacttt aacacgtgaa aatatttcat aggtaaaaga agcatgacaa tttatgacaa
    26341 atccgcgttt tttgtaataa atacagtaat ctatgaaatg aaaagggtta cgtttaataa
    26401 aacttgcttt tttgtttttg ttcaccataa atatttattt aagaaagtat taacctgcat
    26461 ttttctctat aaaaaagatt ttttaaatag ataaaaaagg aggattaaat gagtatttga
    26521 tagtatttat attaaaatta catatgtaat ttaaaaacgc ttgacattgt gtttgagatc
    26581 acttactttt agcatgtaaa agtattggat taaggagcta tgcaaatgaa aaagaaattt
    26641 attactggtg ggattgtcgt tgcatttcta tgtctaattg gctacacagg cacgcggtac
    26701 gcaaatgaaa ttattttgtg gggtggagag acagatattg atacaatcaa tgagaatctg
    26761 acacagcttg atcatacatt gacagataaa gagcaagcga ttacagatct taccgctcga
    26821 ctagcacaaa aagaacagac attgcaagat tcaaaggcag atgtccaaga ataccaaaca
    26881 aaagtaaatg aattagaaaa ccaaaaaaat caatcggcag cagaaaaaca aaacttagaa
    26941 agtcaattag tcagcaagga tgcacaacta caaagcaaac aaaatgaaat caatgtcaaa
    27001 ctagatgaga tcaaccaaaa aaatgatgaa atcaatcatc tgaatgcaga ttggacagca
    27061 agactacaag aagcacaagc aaaactttca gaattacaaa atactgtaaa tggtttgaat
    27121 caacaaatcg caacactgac acaagaaaaa acaaatgtag aaatcagtta acagatacac
    27181 aaaagaaatt agacgaagca actgctgaaa actcaagctt gaaacaatat attcaaaagt
    27241 tagaaaaagc aaaagatgaa gtggaagata cagctgataa atctcagcaa attgttgaag
    27301 aacatttgcg taaataatct ttcttaacaa gtaaacctaa attagtaaag aagcaacagt
    27361 aatctatact gctgcctctt ttttttagta catgtccttc atcttcgcag gaagtgccaa
    27421 tatgatttta agaaaggtaa tagacaaaaa gtcaaaaaga taaaacagag tttcttcttt
    27481 acaaagggaa tgtatgttcg tataatggta ttgaggtgaa ggttatggag aaaaaatatg
    27541 gaacagtaga taagatccgt actttgcaag ttagtgccag accgttgatc cgtttcagtt
    27601 taaatggggt caattgtttg attgcttccc atagtttgaa cttcctagct gaagtagacg
    27661 aagggatgaa gttagtcgtt acaggttatt ataataatag aaagcaattt gttgtgagat
    27721 cctatcatgt gttagggaaa cccaaaattg tggtagaata tgagaaaagt ctatacccaa
    27781 gaaaaaaggt ccgacaagat gaaagaataa actagaaaac aagcggctga gacaaaaatg
    27841 tcctagccgc ttgttttgga aagatggatg cagacgatgg gatttgaacc cacacgagca
    27901 tacgctcaca agaacctcaa tctatatata actacatgta tttaagtatt tgtgatgaat
    27961 cactaaactt tccaaactca tttgagggat attgcttaaa gattgaacag atcaattcga
    28021 agccctatta gtattcgctc aatgggggga tcagaggcca taaaaagaga ctagtcatta
    28081 ctagtctcag gtagtggaat tgtaggattt taaacgttcc tggagagtac cggtatgtaa
    28141 ctcgaagagg tgattatcat agtcgtaaaa gtaaattgaa gaagcctcgc ctttcacacg
    28201 agaacgtcct ggttcgacag ttaaacctaa catttggatt tttgagacaa acgaatctat
    28261 atcttgttcg tcaattttaa aagcaatatg attgtatgtc tttggcagtt tattcgacga
    28321 attctgcatt actgcaatcc ataggtcctt aactaagaaa aatttttctg gatataatga
    28381 aaattttttt gttgactatc gtagatttct tttgcatcaa ataaggtatt taacaattaa
    28441 gtatttaaaa gataactttt aagttatctt taagtaatgc ttaaagctat gttatactct
    28501 attaggaaat ataagaagga gtataaaaat gaacaaacat aatagaaaaa taacgaataa
    28561 caaagaactg atcttgttac taatagggat ttggggtatc tttttactct ttaatatgta
    28621 tatgccgact atgagagcgg atgacgtagt ttatgcaagt agattagatg aacttggcta
    28681 tttgggtgct tcgatagaac attataagac atggagttca agaattatta tagaactatt
    28741 cttaatgttc ttttctaaac actttatgct atggaaatta ttaaattcta cgattatgtt
    28801 aggaattgta gtattacttt gcaagtat
//
LOCUS       DARPZJ010000031        28682 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.032, whole genome shotgun sequence.
ACCESSION   DARPZJ010000031 DARPZJ010000000
VERSION     DARPZJ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.032"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(20..1186)
                     /locus_tag="SLE23_001661"
     CDS             complement(20..1186)
                     /locus_tag="SLE23_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8468566.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1198..1551)
                     /locus_tag="SLE23_001662"
     CDS             complement(1198..1551)
                     /locus_tag="SLE23_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEI8468567.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1679..2701
                     /locus_tag="SLE23_001663"
     CDS             1679..2701
                     /locus_tag="SLE23_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEI8468568.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            2720..2881
                     /locus_tag="SLE23_001664"
     CDS             2720..2881
                     /locus_tag="SLE23_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468569.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(3140..3574)
                     /locus_tag="SLE23_001665"
     CDS             complement(3140..3574)
                     /locus_tag="SLE23_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468570.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(3684..5543)
                     /locus_tag="SLE23_001666"
     CDS             complement(3684..5543)
                     /locus_tag="SLE23_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEI8468571.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(5661..6820)
                     /locus_tag="SLE23_001667"
                     /pseudo
     CDS             complement(5661..6820)
                     /locus_tag="SLE23_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(7127..8551)
                     /gene="araA"
                     /locus_tag="SLE23_001668"
     CDS             complement(7127..8551)
                     /gene="araA"
                     /locus_tag="SLE23_001668"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HEI8468572.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(8567..9265)
                     /locus_tag="SLE23_001669"
     CDS             complement(8567..9265)
                     /locus_tag="SLE23_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEI8468573.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(9222..10883)
                     /locus_tag="SLE23_001670"
     CDS             complement(9222..10883)
                     /locus_tag="SLE23_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HEI8468574.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            11101..12501
                     /locus_tag="SLE23_001671"
     CDS             11101..12501
                     /locus_tag="SLE23_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HEI8468575.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(12753..13832)
                     /locus_tag="SLE23_001672"
     CDS             complement(12753..13832)
                     /locus_tag="SLE23_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8468576.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(13918..14877)
                     /locus_tag="SLE23_001673"
     CDS             complement(13918..14877)
                     /locus_tag="SLE23_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEI8468577.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(14889..16400)
                     /locus_tag="SLE23_001674"
     CDS             complement(14889..16400)
                     /locus_tag="SLE23_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEI8468578.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(16422..16985)
                     /locus_tag="SLE23_001675"
     CDS             complement(16422..16985)
                     /locus_tag="SLE23_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEI8468579.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(16991..17854)
                     /locus_tag="SLE23_001676"
     CDS             complement(16991..17854)
                     /locus_tag="SLE23_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8468580.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(17868..18764)
                     /locus_tag="SLE23_001677"
     CDS             complement(17868..18764)
                     /locus_tag="SLE23_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEI8468581.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(18939..20228)
                     /locus_tag="SLE23_001678"
     CDS             complement(18939..20228)
                     /locus_tag="SLE23_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEI8468582.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(20200..21717)
                     /locus_tag="SLE23_001679"
     CDS             complement(20200..21717)
                     /locus_tag="SLE23_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEI8468583.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            21915..22805
                     /locus_tag="SLE23_001680"
     CDS             21915..22805
                     /locus_tag="SLE23_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HEI8468584.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(22878..23702)
                     /gene="nadE"
                     /locus_tag="SLE23_001681"
     CDS             complement(22878..23702)
                     /gene="nadE"
                     /locus_tag="SLE23_001681"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEI8468585.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(23714..25186)
                     /locus_tag="SLE23_001682"
     CDS             complement(23714..25186)
                     /locus_tag="SLE23_001682"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEI8468586.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(25823..26185)
                     /locus_tag="SLE23_001683"
     CDS             complement(25823..26185)
                     /locus_tag="SLE23_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEI8468587.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            26408..27160
                     /locus_tag="SLE23_001684"
     CDS             26408..27160
                     /locus_tag="SLE23_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8468588.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(27300..28223)
                     /locus_tag="SLE23_001685"
     CDS             complement(27300..28223)
                     /locus_tag="SLE23_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8468589.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(28238..28510)
                     /locus_tag="SLE23_001686"
     CDS             complement(28238..28510)
                     /locus_tag="SLE23_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468590.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8477 a         5988 c         4884 g         9333 t
ORIGIN      
        1 tcccatctgt ctctttttgt tattctttct gctttttcaa cggattttct tcataaagag
       61 aagagattgt tgtgtaccat tcaaaaacat gagtaatcac tactttagct gctgcataaa
      121 caggaatccc caagatcaca ccgatgattc cgaacaattt cccagaagtc agcagaacta
      181 ataaaatcgt tactggatgg attgctaact gattccctag tactaatgga gagatcaagc
      241 gtccttctat tgtctgctct actgcaaaaa cgatcagtac tttgatgatc atgaatggac
      301 ctgctacaat ggctaaaaag atagccggaa tcatcgctaa aaatgatcct aagtaaggga
      361 tcaggtttaa aaaacccgca ataatcccca acgtgacagc atactctaaa ccaatgaccg
      421 caaaaccaat cataaacatg attgccacag caaaagccac agttagttgt cctcttatat
      481 aagaagaaac ttgactattc atttcactca gcacattcaa cgtcggtttt tgcatgcgtg
      541 tcggtaaaaa tttgacaaaa taaggtgcta attgtttacc gtctttcaat agataaaata
      601 agataaacgg catcgtcagc agagccacta aaatagtcgc taccgcgccg acaaaacttc
      661 caagactctg aactgtactc ttagatatat cttggatcat atcgcctgcc gaattcatga
      721 acttatcacc tgctgtttcc aactgttcgc gaaattggtt gaacagcggg tcccgcaaaa
      781 tctcggttaa tttattatca atcgtatcta catattgagg gaagttactg atgaagctca
      841 ctgtttgttc ctgaatctta gggatgatca ctacgctccc ccatgcgatt agtgcaacaa
      901 ccaaaacaaa cagcccaatg atactgtaaa gccttggtac ttttcgcttt tcaaagtaat
      961 caactaccgg attcatcaag taatacaaga ttcctgctaa aatgataggc agacctacga
     1021 ttgctaaaaa ttgccagatt ggtgcaaaca aatatgaaac ttttgtaaat aaaaagacga
     1081 tcagcaatat taacaataca acaagtaagg ctgtgactac ttgattattt aaaaaccagc
     1141 gccaaaacca cgataccggt ctgttcttct tattttttcc ttccataatt cctcctgtta
     1201 gttataaaaa atttggcttc ccaaaccaat agcaggcagt ctatgcggat gaagatagat
     1261 tccatttgca atttgtcctt cttctggaca agcatcaaaa atcaatgata cgtgagctac
     1321 tgtctttaaa ttcccattgg ccatcggacc gacataatcg atcgtatata cctgatcatc
     1381 aaaagcaatt gttccgcctg ctttcaacga aaaaggttcg tcttttgata cttcttgaat
     1441 caccgaatat tttcgtaagg cagctgttgc tgttttatcg aacaaaatca gcatgggttc
     1501 ttccttgttt attgcttctg tcccaatttc tgtaatcttt gcctgaatca ttgcactctc
     1561 tcctttaatt gctttcaaaa acagtataac acattctcat tctttagccg tgtggaataa
     1621 ttatgtgata gaataaaaac gaaaactatt tcattacaat taggaggaat cagctcatat
     1681 gatcgaaaag ataattttag gaacctatac gcgtcgcgaa agtaaaggaa tctatacgat
     1741 cgaccttgat acagaaaaag aagaattagc caacctttca ttagctgttg aagaaaatag
     1801 ccctacctat gtagcaaaaa gtaaagctgg caatctttac acagttacta gtgtggatgg
     1861 attaggtggt gccggtgcgt acgataagga ttttcatttt ttgaatgcgg taacagagtc
     1921 tggcgctcct ttgtgttatg tagcggttga tgaagcacgt caattactat acggggcgaa
     1981 ctatcataaa ggtgaagtaa atgtctacca tatattagga gatggcgaac tgaaagcagc
     2041 agattcaata ttccatcaag aagcgacagg tcctcataaa aaccaagatc atgcgcatgt
     2101 ccactatacg gatctgactc ctgaccaacg attagtcgta tgtgatcttg gtacagatcg
     2161 tgtgtatact tatgatgtgt ccgaaaacgg caaattgaat cttgtaacta ccttcactgc
     2221 agagccagga acaggccctc gccatcttgt ctttcatcca aatggacaat tcgcttattt
     2281 atttggtgaa ttagacagca cagtccgcgt gctttcttat aataaagaaa caggtgcttt
     2341 tgaagaatta cagaaaatat cgaccttgcc agaagaattc gacggtgaaa atggaggggc
     2401 agctatccgc atttcaaatg atggcaagtt cctttatgct tctaaccgag gacataactc
     2461 gattgctgta ttcgcagttt ttgaagatgg ttcccacatt caaaacaagc aaatcatctc
     2521 aacagaaggg gattttcccc gcgatttcgc actagatcca agcaataatt ttgtcgtgtg
     2581 tgccaatcag aacaccgata atctgacatt atatcgccgt catcctgaaa caggattact
     2641 ggaattactg aaaaaagatg tctatgtacc agaatgtgtc tgtgtttatt ttgatcgtta
     2701 gtaagaaaag gagaatgaaa tgaatcagca agacgtatta gacagactac gggaagaact
     2761 aaatattcct ttctttgatg ggaaaatcga agataaagag tatagcgaag aggaatatca
     2821 gaaactcaaa gccgatttac agaactactt tgaacaatat gtacagaatg tagaaaacta
     2881 atcagctttc catactatct gaaaagaaca tcaggacaag acttttccgt ctatcctgat
     2941 gttcttttct acaaataaaa aaccgccgag atggttagac tcgacggaaa aggagtattt
     3001 actcgatttt gagtaagtac aaggttgttg ttggttatag gtatgtcatt atcataaagg
     3061 attttgatca ctctatcata aaggtaatat tacatttata ttagataact ctagttttta
     3121 ttgttatcaa agatttcttt tattttttca acaacaaatt agtcattttt tggatggcag
     3181 ctgtcaattg gtctgtcgct tggtcttgtt ttgcttcaga tgtattgaat agatcttcat
     3241 ctacccctga ttcaagatcg atactttgga tcatttcttc acagcctgct acatatgaaa
     3301 gataagcttt ttcaaaattt ttatgaatgc ccattgcttt tgctggtgga cgcaaagtac
     3361 tgactttcat aagcattgcc cgatattttt ttgttccttc ttcaaataac aggatgatct
     3421 cttcaagagt cgatttgtcc agttcacttg tttttccttc atcaattgcg tttctgatca
     3481 cttcatattt cggatgcatt ccttctccga ttgcttctgt ttccttgacg atttgatcga
     3541 tggactgcac ataatagcca atattcggta acatgttcgt tttcctactt tctccattgt
     3601 tgttattatt tattctactt gtttttatcc tcaaatgaca agtacttgaa aaaatttaat
     3661 ggtttctata cagctcgcca ttcttattcg tgctcaaaga aaccatctgc taaactatat
     3721 tgtttccctg cgacaatgtc atattggatc aattgatatt cgtcgtaaat ctcttgttgc
     3781 gagcgattga attgcgcttc tttataccac tgtccgtttt gatagtacag ttctcgttca
     3841 aacgccggaa gttcctgttc taatgataaa agcagctgat aaaagccatt tgttgtctga
     3901 ttcgtctgtt ccattagatt cgctgcaaaa taaaacggac tggtgattgc atcgtgagtc
     3961 gtttgctttt ctaattctcc tttactgtcg aacataagaa attgtgtttc atgcaatgtt
     4021 tgtttgtcat tttttgcttg gatcgtatct gaatagatcc ctggaagatg atccccccaa
     4081 aaaacaacta aagtccttct agaaagattc ttcaattctt ccgtgaactg cttcagtgcc
     4141 gtgctgctat aggaaatatc ttgcagataa ttctctaagt caagtgtccc acttccatct
     4201 gaagtttttg caggatagtc tagattatca tactttccat cgtagggcat atgtgtctgc
     4261 atcgtgacta aatgaatgaa ctgaggtgtt ttttcttcct tgagaagtgt cattacttct
     4321 ttgtaagctg actcatcaga aatatatgga ttattctcta tcgtatccgt ataggtcatc
     4381 gtacgctcgc tgatgaactg gtcaaatcct aatgtctgat aaacatcctc tcttttatac
     4441 atcgaagtat tgtatggatg gatcgctgtc gtctggtatg attgtgcgtt taacgctgaa
     4501 acgatagaag gaagctgatc catttttggt acaagcatcg tgtaaggggt ggtgagttgc
     4561 gcattaaata acgccataga aaaaccagtc aatgcttcaa attcgatatt tgctgttcca
     4621 ccgccatagt tttgagaaag catattgcca ctatatgttt gatcagctac ttcataataa
     4681 tctgccaatg gctcaccaga tacttctacg ccgtttaatc gactaggatc tgagaaactt
     4741 tcactcatca cgaacacgat gttcggcgac tcttcctcta cagttttatt tttttcatcg
     4801 gctagcttct ggtatttttc agtgatttct ttgatctttt ctttcgaata tccttcaggt
     4861 tcatccattg gttctacctt cagattgtac aaaaacccac cgataaaacc agtgttatag
     4921 tagttcattt tctggctgta aggtatccat agtgccgttt tattatatgc ttttcgcaac
     4981 aaattatcgg gattgttgaa attactgata taccctagca gtccaattgc cacaagcagt
     5041 gtcgttaatc ggatcaattg gaatcgcctt ccttttttca ggcttcgaaa catgtaccag
     5101 caaaacaatc ctatcacggt tcctgcggca gctaagatca ctgtaaacag catagtgccg
     5161 gtcatatctt tcagcaatcc gatttcagtg atcatcttca aatcgtctgg ataaatcggt
     5221 tcttgccgat aactcatttt catataattt gcaaaaccta atacaccgat ggctacgaca
     5281 tacgtaaggg aacctaaagg gacagatcct gctagtgcaa tcagaaaaat aagaataatc
     5341 agcaagacga gacaggctaa gaagaatttt tccgtatgcc aagaaaaagc aaatttcaac
     5401 gcaaggtcta cggatagatc attttgacac cactgcaaaa ataaattact aaaaacaaca
     5461 agaaaaaaga tactgatgat tgctgctgtt ccttttaaaa tctttttctg tttggtcgaa
     5521 agtctgctta tatatctttt caaatgcttg ctccttcatt tctatcaata aaagaatgtt
     5581 gcttctctta ttttagttgt acgaaattcg aaagtaaaga acggaaagaa gaattaatga
     5641 aatccaaata ttctctttct ttatggcctt tctggtttct ttaataagcg gacctttcgt
     5701 actccagaaa ttttttctag ctgttgtttc acttgattga gctgttcaaa atcagtactg
     5761 tctatgtcaa tcaatatgta gacatgctca ttcttatggt tacgcgatat atctgcgatc
     5821 gctagctcgt tctcattcag cagagaaaat atctctgcta atatattggt tttcttttga
     5881 taaaatatag tgaatcgaaa cggcgcttgg aaaaacattc gtgcggatgg ataattgacc
     5941 gcttctctaa ccgtaccgaa caaaagataa tcttttaagg cttcaactgc caaacgtccg
     6001 ctgtctgcca aagcttcctg agtcgatccc ctagatgagg caacataagt atacggtcat
     6061 tttctaagaa ctcttcttct ggaaaatcag tcaagtattt agccagatgt tgtttttcca
     6121 atgcttgcat aacagcatat ttatcaacaa tttcacttct tcctacattg ataagtacag
     6181 catctttttt cattttttct atattcgcct gatcgatcaa tccttttgta tcttctgtca
     6241 acggcagcat gactacgatg taatccgagg tagaaagaac tgtttctaaa tctgcttgcc
     6301 gaacataatc caactgggca tcgcggatag aataacccaa gacatccatc cctaagctat
     6361 agcaacttag cgctactttt gtgcctatcg ctccaagacc aagaagaccg atggttttgc
     6421 cttgcaattc tcgtcccaca taagcacttc ttttgttttc tgcctgttct aaaatattag
     6481 gacctgttag tgtttgtacc atacgacttg cttcgattat cggacgggaa gataagagca
     6541 aacagcacaa aacaagctct tttactgcat tagcatttac acctggtgta ttcatgacga
     6601 tcgtcccgtt ttcagaagct ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg
     6661 aaattgctag caaatctggt gtaagccatt catctttcac tttcgtacta cgaataacta
     6721 ttccttcggc tggcaaatca tctattattt tgaaatattc cccttgtaac ttttctatct
     6781 cttgttctgg aatagcatca atcaaatgaa cgtgatacat aaaaccccct ccttactaac
     6841 aagtatctcg aaatttctgc aattagacaa ctgtttacca tttgacttcc tagaagcaaa
     6901 aagagcagtt agagcagagt aggctgagtg ataaaaataa ggctatgaca agttactgcc
     6961 ataagcctta ttttcgagag caaaatattg agggtgagat atcttgataa atggtgttcc
     7021 gttagctgac attgataata agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa
     7081 tctcttctta tttcttaaaa ctaagtggct ttttcacaac ctctttttat ctaataacca
     7141 ctgtttccaa ctcaactaat tttgcccacg tttcaatttg atctgttgtt agatttagcg
     7201 agacaacggt atgatgaccg ccacctgcct gaatccatga atggacacct tcatggaaat
     7261 tcggtttagt tttccataac acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt
     7321 caaaggcttc tacttcattg atcagcagtt tataatgcgt accgaaatct gccatcgata
     7381 cgactacccc ttctcctgct ttcccatcaa atacaagacg cgccggatct tctctatctc
     7441 ccattgataa aggagaaaca acgattcttg gtttcgtcgc agcaagcgtc ggatctactt
     7501 ccatcatatg ggattccaag attgcttctt ggccactagc tagctcgtaa gtataatctt
     7561 ccatgaatcc tgtatctttc cctcgagcca tgattttcag caaccgatca atcgctgcag
     7621 ttttccagtc gccttcccca gcaaaaccgt atccttctgc catcaaacgt tgtacagcta
     7681 gtccaggtag ttgtttcatt ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc
     7741 ctccttcttc taagaaacgg cgaataccga tttcctgctg agcttgtact tttacatgtt
     7801 cctcccatgt cttttcttca taatcaccat agtcgaaggt atacaattcc ttgtactctt
     7861 caaataattg atcgacttct tcgtctgata cgcgatcgat tacttgtaca agatctccga
     7921 taccaaaata atcaacagtc caaccaaatt gaatctgtgc ttccactttg tctccttctg
     7981 tgacacccac gtttctcatg ttgtcaccaa aacgagccac ttttattcca aaactttcat
     8041 tataggctac tgcaacatcc atccaatcag caatctcttt ttggatctca ggtcgtttcc
     8101 agtagccaac gacgatttta ttttgtttat ttaatcgagc attgatgaac ccatattcgc
     8161 ggtcaccatg agcggattga tttaaattca tgaaatccat atcgatcgtt ttccaaggaa
     8221 tgctttcgtt atattgcgta gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc
     8281 ggatccacat ttttgctggt gagaaagtat gcatccaagt gatcacacct gctacttctt
     8341 ctcgataatt gacctctttc atgatttttg tgatcgtatc agcagtaact gctaattctt
     8401 gaaggcggat tggataaggc aattggccat tttcattcag ttcatcgacc atttcttgtg
     8461 catgtttctt tacttctcgc agtgcttctt ccccatataa atgctgtgat cctacaacaa
     8521 accaaaattc tttttctcca atattcaaca taattagcca ctccttttat ttgttttgtc
     8581 cgtaatacgc attttttccg tgttttcgta aataatgttt atctaaaatc cgttgaggca
     8641 gctcttctga aaatgaattg agctgtctgg taaataaatt catcttgcat acttcatcta
     8701 gtacgactgc gttcattacc gcactttgcg catctttccc ccaagtaaat ggaccgtgtc
     8761 cgtgtaaaag tacccctgga attgctaagg gatcaatttt gcgttctttg aatgtttcta
     8821 tgataacttt tcctgtttca tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc
     8881 gagcacaagg taccgatcca taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat
     8941 ccaatcctgc ttgtgcccag atcgtcgccc atgtcgagtg agtatggacg attcctccga
     9001 tttgaggaaa tgaacgatat aaaacagcat gagtaggcgt atccgaagag ggattgagtt
     9061 taccttcaat gatatgattg tccaagtcca caacgaccat gtcgtctgct gtcatctctt
     9121 cataactgac tccgctaggt ttgataacga aatatcgtgt ttcaggatca aaagcgctca
     9181 catttcccca tgtatatttg acgagtccgt gtttaggcaa gtcaagattt gcttggtata
     9241 cttcttcttt cagttgttcc agcattttct atcactcctt tttcttgcaa ttgatgaatc
     9301 gctgtttttt caatgtcgat cccctcacgg taacgtctca taaatatctg atagcctgct
     9361 atttcttctg ctgaaggtgt gatggtgatt ccttggtctt gtccaaacac gtcttctgcc
     9421 aagaagtttt ctaaagactt cccatgtcga tccatcatat aggctgctaa taacgcgatt
     9481 ccccacgctc caccttctcc ggctgtgtcc atcactgtaa ctggtgcctc catagcagat
     9541 gctagaatcc gctgtccaac ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga
     9601 tcaatttgga cattctcaga tttcaatata tccattccga ttctcattgc accaaaagca
     9661 ctggctaaat ggatccgcat gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca
     9721 aataatggcc ttccttcatt tactcctgta atgttttcac cggaaaaata accataagaa
     9781 agtaatcccc cgcaatccgt atcgccttct agcgctttgt tgaataatac cgtgaataat
     9841 ttatctctgc ttatctccat acccaaagaa ttggtaaatt cttcaaaaat actgacccaa
     9901 gcattgatat ccgaagagca gttattcgta tgaaccatgc ctactagttc tcctgaaggt
     9961 gtagtgacca tgtcgatttc cggatggaca ttttctagtt ctttttctaa tacgatcata
    10021 gcgaaggcgg aagtaccagc cgaaatgttc cctgtccctt tggctacact gttcgtagcg
    10081 accataccgg ttcctgcatc cccttctggc ggacaaaccg ggattcctgg tctcaaattt
    10141 cccgtagggt cgatcagata agcccctgat tcgcttaact tgccagcttc ttctcctgct
    10201 actagaactt taggcaaaat gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac
    10261 tgaccaaaaa tatttttcat ttcttgatgg taggttttcg ttgaaggatc gataggaaac
    10321 atgcctgatg catctcctac gcctagtact ttctcaccag taagctgcca atggacataa
    10381 cctgcaagcg ttgtcaaaaa attaatttct ttcacatgtt cttctttatt caaaatagat
    10441 tgatacaaat gagcgatact ccatctctgc ggaatattgt attgaaattt ttccgttaat
    10501 attcgttctg cttcttcagt gattgtattt cgccaagtac gaaatggtac tagtaactgt
    10561 tccttgctat caaatgctag ataaccgtgc atcattgcac tgaacccaat cgacccgatt
    10621 gtcgtaagat tctcgccata gatttcgaat acttctgctg ccatttttcg gtaactgacg
    10681 cgcagtcctt tccaaatatc ttctaatgaa taggtccaga taccattttc tagtttgttt
    10741 tcccactcat aactaccagc ggcaatagga gtaaaagatg aatcaatcaa tacagctttg
    10801 atcctagttg atccaaactc aatccctaaa gatgtacgac catctatgac atctaacata
    10861 ctttgcgcat ttacttcctt cataatgatt taactccctc cttctcgtca aacctgatca
    10921 aaccgtcttt ttagtagcgc ttacaatgat tattgtatac ttttgtacgt acatgtcaag
    10981 cagttattta caagaataca ataaaaaaca cttgttttgt acgtacataa gttataaaat
    11041 gaaattgctt acaaaatctg atcaaccgcc ttctcgaaat tctagaagga gagaatactt
    11101 atgaaaaaag aaaaaaaagt ttcctcatcg tttatttatt tttttggcgc atttggcggc
    11161 attctatttg gatatgatat tggtgttatg accggcgcct tacctttttt acagcatgat
    11221 tggggtttgg caggtaaagc ttctttgata ggatggatca cgtcttcggt catgttaggt
    11281 gcgatccttg gcggctcttt atctggtctt ctttctgata agcttggacg acgaaaaatg
    11341 attcttcttt ctgcacttat ttttatggct ggttctgtcc tttctgcatc tgcccctcac
    11401 aatggttctt attttctgat tgcagcaagg attcttctag gtttagctgt tggcgctgca
    11461 tctgccctag ttcctgctta tatgtctgaa atggctcctg ctagactaag gggaagattg
    11521 tcagggatca atcaagtgat gattgcttct ggcatgctcc tttcctatgt tgcagattat
    11581 ttgctaaaag ggttgcctga aacgatggct tggcgcgtga tgttagggct cgctgctgtc
    11641 cccgcgctga ttttattttt cggtgtttta gctctaccag agtcaccgcg ttttcttatg
    11701 caatctggcc gcttggaaga ggcaaaaaga gtattgaact atattcggac accaaaagaa
    11761 gctgaacagg aattcgaaca aatccagctg aatgtcaaac aagaaaagac aaccggaact
    11821 tcttggcata ctttgttttt agaaaaatat cgttccttag tcattgccgg tattggtgta
    11881 gcagtattcc agcaatttca aggagctaat gctatttttt actatattcc gctgatcgta
    11941 gaaaaagcga ctgggcatgc agcgagcgat gcattgatgt ggccgatcat ccaaggaatc
    12001 attttagttg ctggttcttt gctctttttg gttattgcag acaagttcaa tcggcgaact
    12061 ttattgaaaa taggcggtag cgtgatggga ctttctttca tcctaccagc tgttttagga
    12121 actgtactgg atgctcatac aaattcgttg ttgattctct tgtttttatg tatttatgtc
    12181 gcattttatt cttgcacatg ggctccactg acatgggtaa tcgtaggcga aatattccca
    12241 ctagctgtcc gcgggcgagc atctggccta gcctcttctt ttaattggat tggttctttc
    12301 ctagttggct tgctttttcc tgtgatgact gcttctatgt ctcaagaaat cgttttcggc
    12361 atttttggga tcatctgctt tttaggggtt ttatttattc aagagatcgt accagaaact
    12421 cgtgggaaat ctttagagga aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt
    12481 atttctatcc atcattctta aagaggttgt gacagaagtg gtcagcttca agaaataaga
    12541 aggaaccgct tagtttccag tcacaaggaa caatttcaaa aaacagcttc tcatgtttga
    12601 tgaatattgt gacttgtgac cagttggtag gagaacaccg tttagtggag aggtggtgaa
    12661 agaaacgttc agccttgagc gatgacaaaa gctctcacaa acattgcgac gagtaaccgt
    12721 aggagcaata agaggcggta aaaacccgtc tcttattttt cgttttcttt cactgtttcc
    12781 cgttcaacta gtacaggttc atagagaata tttggctgtg cctgtccttt ttcaatcgtt
    12841 gtgacgatcc accgtgcggc atcttgtccc aacttttctt ttggatgcgt caatgttgtc
    12901 aattttttat tccctaaatg gcttaaagaa gaatcgtctg ttcctacgat cgataggtca
    12961 tctggaatat gatagccatt ttctgtcaac ttatctagca ttaaactagc tatttgatcg
    13021 ttatagcaaa tgatgccatc taaagcttgt tcttctttca accgttgtac tgttttttca
    13081 gcgattgttt ctcgtgtttc cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca
    13141 ttatactgtt cacacgcgct gataaaacct ttcatcctgt attttccttg aagatcgtcg
    13201 atttttgtga tgaacaacag acgctgatgt ccttttttta tcaaatattc tgctgccata
    13261 aaaccgactt tcacatcatc taaacaaata taagaggcat ttaactcttc ataagcagca
    13321 ttgatcatca ccatcggaat gccttgttct ctcaaagcaa cataaagtgc taagtttggg
    13381 ttatactgat tacttttcgt aggctcaacg atcaaaccat ctaccccata agcaatcatt
    13441 ttcttcaaac actctttctc caattcgtga tcgttattcg tactggctaa aagcaatgaa
    13501 tacccagatt ctcgtaattc attttcgatt cctcggataa tcgacggaaa aatataatca
    13561 gagagatatg tggtgatgac accgatcgtt tttgttctgt tcaatggtgt tttttctttc
    13621 ttatagctgt catctacata tgtgcccgac cctttttctt tacgcagata gccctcattt
    13681 accaacacag cgattgcttg ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc
    13741 ttgaattctg agggaatggt tgtatttact tcgtattcct cacgaaggat cttttgtttt
    13801 atctcttctg caatatcttg atattttgcc atttgccttg ccccttttta tttgtacgta
    13861 catatatcat aacgagtctg caaggtttat tcaagcaaaa atcaaggttt cttgtgctca
    13921 taaggcatac ggaacaggtt caccaaattc tggaaatcct tgctcattcc acgtaaagca
    13981 ttgcgcgttc gcgtgccgat taggattgtc taacggatcc cctttttggt tcttctctgg
    14041 tcgagcatga tagatcaaaa tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg
    14101 accaggacca aattgcttat ttttttcaga agaaacgaat actggctccg ataatttatg
    14161 ccatgattct tttaataaaa gattcttgtg ctcatcagcc cacagcaggc ccatggcata
    14221 gttttcatct gttgcactac cagaatacgt aatgaatatt ttcccattgc gagtaaggac
    14281 tgctggacct tcatttactg aaaaaccccg tttttcccat tcatactcag gtatagaaag
    14341 gaggatctgc ttccccttta acgtccaagg attatccatt tcggatagat aaagattaga
    14401 attcccagta atttcaggat cttgttgggc ccacacataa tatagctttc cttgagaaga
    14461 gaaagttgtt ccgtctaaac tgaaagtttc ccttttcgtt tttatttgtc ccttttctat
    14521 ccaatctgta ttcattggat ctatatgctg attttcaagt acgaacatgc ggtgatgatg
    14581 agattcatca cgtatagttt tatgattgct tgcagcaaag taaatatacc attttccatt
    14641 gatataatgg acttcaggtg cccagatcaa ttcactcatc ggtccttctt catgagcctg
    14701 ccatacaatc aggcttgcag catgttctaa ttcattcagt gactttgccc ttcttaattc
    14761 aatcacttgg tagcctggaa ccgatcctgt aaaataataa taaccatctg tatgtttata
    14821 tacccaagga tctgcccgtt gccgaacgat aggattatta taaagtgtct tcatcataac
    14881 aaatttcctc acattttctt tattctaatt acattccaag agtatttttc tatccctaca
    14941 tttaattcgt catgtttttc tattgaaaaa tagtttattt caggttttat tttttctggt
    15001 tcttcacgtg tatttttgtc caacagatcg ctactggtta atgtgtagtg ctctccttga
    15061 tctagcaaat tgaaatcatg ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc
    15121 aagaaaatag tcagctgatt gccgttatct acgatcacac tgtccacata aggaacattt
    15181 tttatctttt cacaatcata aacagggcaa atgatttgtt gtttcaatac ttgaccttta
    15241 gcatatttcg ataagtgttg catcacataa taagttggat tcctccatgc ttgtccttta
    15301 gcatctgtca gtattaaagg tattgtgttt actaacaatg attgacaact aatctttacg
    15361 cgatctgcgt gtcgtaaaat agccagccct aatgaaccaa ataataatgt atcttccata
    15421 gtaaagtaac accaatcgat gggactaccg acttcaaaat ccctatgtct tttttccggt
    15481 tgggcatgta cattccattc atcaaacgct agatacattg ttttctcact tctcaaatat
    15541 ccttttacat aatcacaagt agcaacgatt tcttcaattt gacgatcgaa tcgataagct
    15601 tttgcaaggt atgtcgctgt atcatcacgc tcatttttag gaggtttagt caagtcttct
    15661 tcatcatact tatcaatata gttatgcaaa gctaaataat ctacattctc ataagcttct
    15721 tctaatgcga tacgatccca ttcagggtac gatggtaaac gtggcgtaga gcttccaact
    15781 aagattgttt caattgaatc atccactaac ttcatgactt ttgaggcttc atttgctaac
    15841 ctaccatatt cataagcact cttagccccc acttgccatg gaccgtctag ctcattccct
    15901 aaacaccata atttaacgcc aaaaggcttt ttttgcccat tttttattct taaatcactc
    15961 cagaaggttc cttttggaaa attacaatat tctactaaat tttttgcttc atcaattcct
    16021 tttgttccta aattcaccgt gaatatcggt ttcgcttgta catgactgat ccatttaaaa
    16081 aattcgtgga gtccaaaaga atttggttct atacctcgcc atgctaaatc aatttttttt
    16141 ggtcgttgtt ctttcctacc tacagtatcc acccaatcat aaccagatgt aaagtttcct
    16201 ccaggatagc gaatgacacc taattctaat tcctttacat aagagaggac atcttgtcta
    16261 aacccgtcac catcagctgt ttcatggccc ggttcataaa tccctgtata gacgacactt
    16321 cccatatgct caacaaatga gccaaacagc cgagaactga tctctcctac cgtaaaatcc
    16381 tctctgattt ttactttcac ttcttcgtcc aacagctttc cctacctttc atttcctata
    16441 gtcaagataa tagatacaag tttccatacg ccaccagcaa agataaaaat aaaaggaggg
    16501 aaaagaaata tgagcagtac aaatcctaat aacaatacgc aacaaagaat atttctcaaa
    16561 aaatcaaaaa atactttcca tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg
    16621 ttttcagaaa tcacatatat ccaggataaa agaaacatgg aataaataag taaaactaca
    16681 tatccactaa ttgaaagtac gattgtctgt tcttctaata attgattaac aagaaaataa
    16741 ataatgatcg ttaacagact aaggaacaag ttcttaccaa aatgttgctt tattccttga
    16801 aagaaaaaat aaatgatatt tcctgatccc tcacctttcc attgcgccat tacataaaaa
    16861 acagcacatg tagcaggcac gatagtaata acaggcaaac acacgattac ccagagaata
    16921 cctaataaga tgtaatcaga aaccacaatc aactgtccat aaagtttagt ctcaactatt
    16981 ttcatcttcc tcactctttc attccagaca tagctgttcc ttgaacaaaa tatttctgtg
    17041 caaaaatata aaccactagt aatggcagca ttgaaataac cgttccagcc attacaggtc
    17101 cataaaaaga aatgttctgc cctgtaaata aagctaaccc tgctggtaaa gttctcattt
    17161 ttgaactact tgtcaatatc aatggataaa gcaagtcatt ccaactattc atcagcgtga
    17221 aaatccctaa tgataaaaga gtaggtttgc tcaatggcaa catgattttc aaaaaaatat
    17281 taaactcact taatccatca atgcgtgctg cctcttccaa agaatctggt aaagtaataa
    17341 aaaaggaacg catcatgaag ataccaaatg cagttgtcat acgaggaatg atcaaacctg
    17401 cataagtatc aagcatgcca agcaaattga cttcaataaa tagaggaatc atgaagactt
    17461 ggaatgggat catcattgtc agcaaaacga aatagaacaa aactgatttt cctttgaaac
    17521 gcatacgagc aaatgcatac cccgcaagag aatcaaagaa tacagaagtg atcactgtcc
    17581 ctccagcaaa aatcactgta tttttgatgt aatctaataa agggatcgtt gtccaaacct
    17641 taatatagtt atctagggta tagctatctg caaatattct aggcggaaat gagataatgt
    17701 ctttttcgtg tttaaaagaa gaaataatca gccacaaaaa aggaaacgca ataaccaaca
    17761 atataactag catactaatc gttcgaatga tttttttacc actaactgct tttcgactat
    17821 tcacagtaac tgtaatcgag ctttctggtg ccatacaggt ttccctccta tttcatttgt
    17881 ttttctttcc gtgacatgta cacattagtg gagatagcta tagttgcaac aatgataaac
    17941 aaaaccgaag acagtgctga tgcatagccc aattcataag gtgctgtaaa tcctcgactg
    18001 taaatatatt gaacagctgt ttctgtctta aattgtgggc caccagcggt tgcaacatat
    18061 acttggtcaa acacttgcat cgaaccaatc agattcgtta aaatacaaaa acctaaggag
    18121 ggaacgatct gaggtagcgt aatgttaaaa aactgctgtc gatttgttgc accatccatt
    18181 tgagcagatt catacaaaga gggagagatt ccctgaatag cagtcaagag aatcgtcata
    18241 gtaacaccaa aattcttcca aacagtcatg atggctaccg tcggcatagc aagggttgga
    18301 tcgcgaaaaa attgagggat cggcaagccg acttgtgaaa acaagtaagg aatcgcccct
    18361 acattcggat caagcaacat agaaaaaata atcgcaattg acgtcaatga acaaataact
    18421 ggaatgtaaa atgtcgaacg acaaaaacga ttgaatctgg tatttttaga taatgctact
    18481 gctgctaata aaccaacgat aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa
    18541 tgaatcaacg aattaactgc tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt
    18601 acaaaatttc ttgatgtaaa gaaaatattc aaatctgtaa aactaatagc aaatgttcct
    18661 aaaagcggta tgacagtaaa taataataaa actaaaaaag atggagttaa aaacaaatac
    18721 gcagcacgat caggacgatt ccaatatttg gtgaatccgt tcatatagtc cacctcatct
    18781 ttcattttga taaaatatac aatcttggtt taaacgaatc tgaataagat atccgaacaa
    18841 tcgctgtgat ttttgcaata acacctatct gcaaatacta ggtcgatcat tcagatatct
    18901 gtatcttgcc aacagtctat cctgtataaa gttctgtact atttttgcag taattgattg
    18961 atggcatcat ctgcatcgtt catgagtgtc tcaggatctt ctcctgctaa taatttttca
    19021 atcagtggat tgatgatatc gttattgatc gcagagattt gggtaaaacc tggtaaatat
    19081 ggctctgcat agtccatttg tttcgataat tcagatacaa taggatcatt ttttacttct
    19141 tcatcttttg ctactgaatc caagtaggca ggaaaaccat tttcgatact ccatttttta
    19201 ccaatttcag ttgtattcca atatttcaaa aactcataga cagcttcttt tttattatta
    19261 tctgtacttg ccggaatggc atatcctacg ccatctaaaa tagctgtttt tttgtctgaa
    19321 tcactccctt gtggtaaggt agtcacatta taatcaatct cgtttgcttt caatccgtta
    19381 tttaaccatg gcccattgat ttcaatggct agttgaccag cattcattaa attgtccatt
    19441 tcggcgccag aaatcgattc tggaccagtc ttgtctacat ggatcatttt ttggatcgct
    19501 tttaacgttt taaggttctc aggagacgca aattcagact tagtataatc atcgttcact
    19561 aatttaccgc catttgctaa catccagtta tataacggtg cagttccatc cttattgaag
    19621 acaaaacctg atacattttt actactatca gttaattttg gtgccatttc tgtcaattct
    19681 tcccaagtag taggtggttg ttcagtatct aatccagctt gtttaaacaa atcattattc
    19741 caatacatat acatgccttg tacctgcatg gggacaaaat actgtttacc ttctacttca
    19801 cctaattcaa tagccgtttc tttaaaatca gatttatcta ctccatcata ttcccagaaa
    19861 tcgtctaatg gttgtaccgc tccgttttct acatactgtg caaaatctgg ataatttaat
    19921 gcaataaagt caggtgcttt tttagaagaa atcgctgtag gaagtttttc attcaaattg
    19981 gcccaagtca tgatatccat ttcaattttg atgtttttat catttgtttt attaaattca
    20041 ttaacgattt cttgcaatat ttcaccatca gatgcagtaa acccattcca aaaagtcaaa
    20101 gtcacttctt tatcagaatc agattctgct gaacttccgc caccgcaagc tcctaaaata
    20161 cctgttgcag ctaccaacaa agagccaatt aaccattttt tacctttcat tttttgttcc
    20221 tccttcatct gataaacgac atctgaccac attccaagat agcggtttca ataaacaatt
    20281 gattttccca tcttcagctt ttacatttgt tgaatgactt ggttttactt gttcactttt
    20341 aggaagatta gttgcttttg tatcaaatcc actcatttca gaaaaatcaa tcactccctc
    20401 taatgataat tcagacaagt gaacagttag attcatttct tcttctccac ggttaactgc
    20461 aaatatgaca agttctttgt catttattac ggctatactt tctaaatacg gcacttcttc
    20521 aaaatcttcc gtcgcatagt ttgctgaacg aatttgtggg cttaacacct ctccttgtcc
    20581 atacacagca gcttgcataa atggataata gatcgtctgt ctccaagctt ctccgtttgt
    20641 ttctgtcctg attggtgcaa taacatttac caattgagca agacaagcaa tctttactct
    20701 atctgcatgt ttcaataaag tgattaatag acagcctaat agtaatgcat cttcaaaatt
    20761 atagttatct tctagtaaag gaggagcaat ctgccaaggc gctgcttgct catcttgttc
    20821 cgctgaatga taccaaatat tccattcatc aaaggacagg ttgatctgct tcttactatg
    20881 tttcttcgcc ttgactgtat cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc
    20941 taaggaacgt gcaagataat gagaaagatc atttttttgg ttgccataat attgatgcag
    21001 agacaaataa tctatttgat cgtacgcttg atcaagaact gttaactccc aatcaccaaa
    21061 tgtaggcatt tgccgattcg aacttccgca taaaaccacc tcaattgaat catctacgag
    21121 tttcatcgcc ttagccgttt cctctgctaa ccgtccatat tcttccgctg ttttatgtcc
    21181 aatctgccaa ggaccgtcca tttcattccc taaacaccat gtcttaattc caaaagggct
    21241 ctcttgacca ttcgaacgcc ttaaatcact ccaataagtt cctttaggaa aattacaata
    21301 ttcgactaaa ttacgagctg catctactcc acgagtaccc agattgacag ccatattgat
    21361 ttcggccccc acatgctgac accagttata aaattcatga atcccaactt cattcgtttc
    21421 aattgtccgc caagctaaat ccaaccttct aggtctattt gctatgggcc caatactgtc
    21481 ttcccaacga aatcctgaca caaaatttcc accaggatat ctaatcatgg gaatgttcaa
    21541 ttcttttacc aagtgaatga cgtcttggcg aaatccactt ttattagctg atggatgatc
    21601 tggctgataa atcccttcat atactgctcg tcccatatgt tcaataaatg aactgtacaa
    21661 ccgcggatca actttgccta cacgcttgac actactaatc aacattgtgg cttccataac
    21721 tgacctcctt taatttatac atgaataata cacctcgttg aaagcgttgt caataatata
    21781 aatgttaaac ttacttattt tttatcgatt ttaattaacc aaaatattaa taatgattaa
    21841 aacaaataat ttaatataac ttttattaac aaatatgtta atatataaga aaaacctttt
    21901 aagaggtgat atatatgcaa ctacaaataa acgaagaatc cttaccggta tatgaagcat
    21961 tagctagtaa aacaaggatc aagatcatcc agctactttc caaaaaaaag atgaatgtca
    22021 aagatttggc aaaagaactt ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc
    22081 tagaggaagc aaacatcatc aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc
    22141 gtgtcgataa aatcgatatc agttttccag aaaaaatatt caatgctttt gatacgaaag
    22201 aaacatcgat acctattggt cactatacaa attatgcaat tgaaccaaca tgcggtttag
    22261 ctacgatcca tgattttatc gggaaagtgg atgaaccacg ctattttatg gatcctcgaa
    22321 ggatggatgc ccgcattctc tggtttacca gcggatttgt cgagtatcag gcacctaatt
    22381 ttttaaatac agaggataca ttggagatgt tggaagtttc tgtggaaatt tcttctgaat
    22441 ttcctttttc aaatgacaat tggccttcag atatcacttt cagcctaaat ggtgtggagc
    22501 taggaacatg gacgagccct ggagattttg ctgatatccg cggtaaatat acgcctgatt
    22561 ggtatccaga taatcttaat caatacggct tgctgaagac gatccgaatt accaaacact
    22621 tgacgaatat gaatggagaa cccttgtcaa acatcacgat caacgacatc cctaaagagc
    22681 aagacacttg gcatttgcga atcgaagtga aagacgatgc caaacatgtg gggggctgta
    22741 ctttatttgg taaaggattc ggtaattacg atcaggatat caaattaaaa gtttactaca
    22801 gctgatattt ttcttttcta ttttataaaa caaaaacagc caatccctat gaagggacgg
    22861 ctgtttttgc tttattgtta tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt
    22921 ttatgttgtg tcttgttcca ccatgcttcg attttttctt gtgcttgagc gggaacttct
    22981 tttccttcta gataatcatc aatttcatta tatgtgacac ctagtgcgac ttcatctgca
    23041 atcattggtt tcccatcttc aagatctgca gtcggaattt ttgtgtataa tttttccggt
    23101 gcattcaatg cttgaagcaa ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa
    23161 atgtcggctc caccatcacc aaatttcgtg aagaatccag taatgttttc tgcagcatga
    23221 tctgtcccta atacggctcc tgctctttct ccagctacgg catattgcgt aatcatacgt
    23281 tgacgtgctt tgatatttcc tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat
    23341 acttgtactt gtgcatcaac agctggtttg atatttactc gcagactaac atcgggctgg
    23401 ataaagtcaa gagcagcttt tgcatcttct tcatctgctt gttcaccata aggaagacga
    23461 acagcgataa attgatagtt ttcatctttt gtttcttcac gcatttcttc catcgttagt
    23521 tgcgccaaac ggcctgctaa agtagaatct tggccgccgc tgatacctag tacaaaagtt
    23581 ttaagaaacg gatatttttt caaatatgct ttcataaagt caatactttt acgtatttct
    23641 tcttttggat caattgttgg tttgacacct aattcattga taatttctgt ctgcaggctc
    23701 atttattctc ctcctatgct tctgtatgaa gttctgctac gctttttttc attcgttcca
    23761 tgatagccat tttatggttc cagcattcag tagacagatc gactgggtat ttttgcggat
    23821 tcaagtctcg tttatactct tcccatagtg aatctagatt ttcttttgta tattctttga
    23881 tttcgtttag tgcaggtaat tcgtaaactc tttttccttc gataaagata tcttgtaaaa
    23941 ctgggcgagc tgtaaagtct cgaacagttt tattgataaa cgtatgcact ggatggaaca
    24001 tgaagatagc ttcttcttct cgagggtctt catcccataa tgtcacgtag tctccttcag
    24061 atttcccatc aaaatttcga gtgatgcgcc acacttgttt tttccctgga gtagttactt
    24121 tttctgcatt gcttgataac ttgatcgtat ccatcatttt tccttcatca tcttcgatcg
    24181 atactagctt gaatactgca ccaagggctg gctgatcata ggctgtgatc aattttgtcc
    24241 caacacccca tacatcaatt ttagcttttt gcatctttaa attcaaaatc gttgcttcat
    24301 ccaagtcatt cgaagcatag atttttgctt ccgtaaatcc ggctgcatct aattgttccc
    24361 gaacacgctt agatatatag gccatatctc cactgtcgat gcgtacgcct tggaagttga
    24421 ttttgtcacc taattctttc gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat
    24481 cataagtgtc gactaagaac acgcagtctt tatgggtttt agcgtaggcc ataaatgctt
    24541 cataatcatt tccataagat tggactaacg aatgagcatg ggtcccgcta gctggtatcc
    24601 caaatatctt cccagcacgt acattgcttg ttgcatctgc tccgccgata tatgccgctc
    24661 tagttcccca gactgctgca tccagttctt gtgcccgtct agttccaaat tccaatagtg
    24721 gatcttctcc gatgacagat ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat
    24781 tgaccatatt caacagtgct gtttctacta attggcagtg cgctaaaggc ccttccactt
    24841 ggattaatgg ttcatttgca aaaactagtt ctccttcacg agcagaacga actgttgctt
    24901 taaattcaaa attttgtaaa tactccaaaa aaccttcagg atagacttct aatccacgca
    24961 agtaagcaat atcggaatca ttgaacgtca gattctctaa ataattgact aaccgttcca
    25021 atcctgcaaa aaccgcgtat ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa
    25081 cagcatgtaa atcagctcga cctaattccc agtatgtctg catcatattg atttgatata
    25141 gatccgtatg cagcgtcaaa ctgtcgtctg ggtaagtatt attcatcttg tattactcct
    25201 cttggcaagt tttcatttcc tacccattat aacaaaaaaa attaatagga aaagaaatct
    25261 tccatttttt ctgaaaaagc acatgtttta cggatatttc ttgctaaaaa tgaactccat
    25321 ctgctaaaac tatcctttct tattggtatt taacctaaac gagaaagaat acttatttta
    25381 ttcaatgtat ccgagacacg aagaaattag cgttttctat ttttcttact tgataaaata
    25441 agtagatttt cctactacaa tcgtagccgt taagataccg atgattgaac aaatataacc
    25501 aaatgtctct acaacataat caatggcaaa agtttttgaa gcaataatac gtctttcctt
    25561 ttttgcttct tatccccaaa gaaacggata taacttatta tgtattgaat ttttttggaa
    25621 aggcgaatta tgacaagata taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg
    25681 tttttaaaaa gatacaaagt aagaaagcag ctgtcaatag aatggaaaca aaaatggcga
    25741 gacatcaatc agtctcgcct tgttttttat tgtatacatt agatatggag caggttacca
    25801 taaagatgat tattagtcgt tattaaatag aatccttcgt atttttttgt tctatcacta
    25861 caatatcttt atttggacgt ttgaattgta ttccggcacg ttctagctcc tgtttcactc
    25921 ctacatggac tttgacatct tctcgtgtca tttttaaaac gtgatgaatc gcatagtcga
    25981 tttcttgcct tgtgattttt ttcttcgtat tgatcatcac gacttgcttt ttatcatatg
    26041 tgtctaccaa tagcagttgt gttcgatcta acgaaaataa tttgtaataa ttaatagccg
    26101 tattcccaaa aaagaattcc actactttag gataaaatgt cttaatattt aaattactat
    26161 tcacaggtgt ttcgattagc ttcatctcat tcctcttttc tatatagtcg atttagatcc
    26221 aatcttaagt tatgttacca tctttcctag cattaaggaa tcggttacaa ttgaaccttt
    26281 aaagacaaaa ggatttacct tttatcactt aatagtataa cataatttcg tgagaaaaaa
    26341 atacaatttt ttcttgacca tctcgttacg taaaggatta tgcttacatt tgtcaggagg
    26401 aaaaataatg gagtacacaa taaagaaaat gtcagagata tcaggagtca gtccgagaac
    26461 cttgcgcttt tatgatgaga ttggactgct aaaaccagct aggatcaatt cttcaggtta
    26521 tcggatttat ggcaaaaaag aagtcgatcg tctgcaacac atcttatttt atcgaacaat
    26581 ggcattcaag ttggatgata tccaagaggt cttagacaat ccatcttttg accaccagaa
    26641 agctttaatc aagcatcagc aaatgttgct ggaaaaacgg gcacaaatcg ataccctctt
    26701 gacaactgtc caacagacac ttgatatgta cgaaggagga agaaaaatga gtgacaaaga
    26761 aaaatttgaa gggtttaaac aacaaaagtt gaaagaaaat gaagaatcct atggacaaga
    26821 gattcgacaa aaatacggaa aaaaaaaggt tacagcatcc aatgaaaaat ggatgaatat
    26881 ggataaagaa acgtatgaag aaatgcaaac tgttgaaaag cagatgttat ttgatctcac
    26941 tctttactta aaagaaccag aagatgaaag cttagcagac cgtatcttcc aagctcataa
    27001 gaagtggttc tcttacagct ggcctgaata tcagccaaaa gcgcataaag gactaggaat
    27061 gatgtacgaa gccgatgaac ggttcactgc atattatgac gagcgaagtg gtcatggtgc
    27121 agcaaaagct ttaaatgaaa ttatccaaaa aaaggcgtaa tcttttacat gatccaacaa
    27181 aaaagtacac gtaaaatgac ctaataacaa aacagcagac acccaagtta gatttttatg
    27241 ctaacttttg gtgtctgctc cattctttca caagtttttt catcctactt taaatatatt
    27301 catcgttgaa taaacgtata aggtattttc actttatcct ttttttctgt aagaaacaat
    27361 tgaaatgcca tttctccgca agcttccaga tggtggtcga tggttgggaa accaagaagc
    27421 tcgctgatca gcaaattatc gcgtccaatc accactggtg tcttatcttg cagatagctt
    27481 tgcaagatgc ctgctgcaac catatccgaa tttgtaaaga caccatcaac tccaagctct
    27541 ttaaaaaaga agcctgcttg ttttcctttc tctgcatcta tacaatccca aaaaacaagt
    27601 gattcatcaa aagatggaaa aagttgatga catagctgca aagtgatttt tgagttataa
    27661 cttagcctgc cacttcgccc caacgtgatg cccaattgct ttataccttg ctgcttcaaa
    27721 taagtaagac cttctgtaat tgattgttct cgatcaataa agacacagct tgcctgtttt
    27781 cccttgattt cttcacaaaa aactagaggt ccatattttt gatatgccaa taaatcatct
    27841 agtgtattgg cacgagacgt aatgatcaat ccatcgaaag ctttagctgc aaattcttca
    27901 agataccttc gctctttttc tttatgatag cccgtcggta aaagtgtcac tttgtaatca
    27961 taatcaaacg ctgcttcaat gatcccactg atcaactgat caaaatacgg atgattggta
    28021 taaggcagaa tcactccaat gcttttcgtt tttccataac ttaactgtct ggcatttgca
    28081 ttagggatat aatcgacttc tttcatgacc gcaagtattt ctttcctttt ttcctcatct
    28141 acatatggat gtccattgat tacacgtgaa atagtagaaa ctgaataacc tgtgagcttt
    28201 gcgatatctc gaatgtttgc cactgctgct tcgccaccta tacaaaaaga ttttcttgta
    28261 aatagtctac cacagctgga ccgcattcaa aaaactgata catttttcct tcatgcgaaa
    28321 aactgatccg ctgcccgccc caatatatat cttttgtcaa attttcgatt tcattcattg
    28381 gtatttcttt tactatattc ctattcaacc cttgaaaact gtacaacgtt aatacggatc
    28441 ccttgaactc gacaaacgca taaaaataat tgttcgttgt gccatctgtt atctctacat
    28501 aagtattcat tgcaagccct ccttttgata ctttgagtat agtgtatgaa acgcgtctca
    28561 tagcaaggag tttgttttgc caaagaaaag ttttattcct ctttcattat taccaaagtc
    28621 tcttatttta aattgaatac attataatga tactgtaaat atatctttat tattagtgaa
    28681 tg
//
LOCUS       DARPZJ010000032        27311 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.033, whole genome shotgun sequence.
ACCESSION   DARPZJ010000032 DARPZJ010000000
VERSION     DARPZJ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.033"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            647..964
                     /locus_tag="SLE23_001687"
     CDS             647..964
                     /locus_tag="SLE23_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEI8468591.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="SLE23_001688"
     CDS             complement(1055..1420)
                     /locus_tag="SLE23_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468592.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="SLE23_001689"
     CDS             1628..2110
                     /locus_tag="SLE23_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468593.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="SLE23_001690"
     CDS             2307..3197
                     /locus_tag="SLE23_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEI8468594.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..4758)
                     /locus_tag="SLE23_001691"
     CDS             complement(3484..4758)
                     /locus_tag="SLE23_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8468595.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5031..7502
                     /locus_tag="SLE23_001692"
     CDS             5031..7502
                     /locus_tag="SLE23_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEI8468596.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7605..9341)
                     /locus_tag="SLE23_001693"
     CDS             complement(7605..9341)
                     /locus_tag="SLE23_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEI8468597.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9338..10042)
                     /locus_tag="SLE23_001694"
     CDS             complement(9338..10042)
                     /locus_tag="SLE23_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8468598.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10173..10676
                     /locus_tag="SLE23_001695"
     CDS             10173..10676
                     /locus_tag="SLE23_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HEI8468599.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10636..10974
                     /locus_tag="SLE23_001696"
     CDS             10636..10974
                     /locus_tag="SLE23_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEI8468600.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10995..12413
                     /gene="ffh"
                     /locus_tag="SLE23_001697"
     CDS             10995..12413
                     /gene="ffh"
                     /locus_tag="SLE23_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEI8468601.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12525..13103
                     /locus_tag="SLE23_001698"
     CDS             12525..13103
                     /locus_tag="SLE23_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEI8468602.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13107..13628
                     /locus_tag="SLE23_001699"
     CDS             13107..13628
                     /locus_tag="SLE23_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8468603.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13707..14261)
                     /locus_tag="SLE23_001700"
     CDS             complement(13707..14261)
                     /locus_tag="SLE23_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEI8468604.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14514..14789
                     /gene="rpsP"
                     /locus_tag="SLE23_001701"
     CDS             14514..14789
                     /gene="rpsP"
                     /locus_tag="SLE23_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEI8468605.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14801..15052
                     /locus_tag="SLE23_001702"
     CDS             14801..15052
                     /locus_tag="SLE23_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEI8468606.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15177..15968
                     /locus_tag="SLE23_001703"
     CDS             15177..15968
                     /locus_tag="SLE23_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468607.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16138..16659
                     /gene="rimM"
                     /locus_tag="SLE23_001704"
     CDS             16138..16659
                     /gene="rimM"
                     /locus_tag="SLE23_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEI8468608.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16649..17410
                     /gene="trmD"
                     /locus_tag="SLE23_001705"
     CDS             16649..17410
                     /gene="trmD"
                     /locus_tag="SLE23_001705"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEI8468609.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17546..17893
                     /gene="rplS"
                     /locus_tag="SLE23_001706"
     CDS             17546..17893
                     /gene="rplS"
                     /locus_tag="SLE23_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEI8468610.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            18266..18928
                     /locus_tag="SLE23_001707"
     CDS             18266..18928
                     /locus_tag="SLE23_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468611.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            19007..22234
                     /gene="fss3"
                     /locus_tag="SLE23_001708"
     CDS             19007..22234
                     /gene="fss3"
                     /locus_tag="SLE23_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEI8468612.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            22348..22662
                     /locus_tag="SLE23_001709"
     CDS             22348..22662
                     /locus_tag="SLE23_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8468613.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            22675..23049
                     /locus_tag="SLE23_001710"
     CDS             22675..23049
                     /locus_tag="SLE23_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8468614.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            23059..23403
                     /locus_tag="SLE23_001711"
     CDS             23059..23403
                     /locus_tag="SLE23_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEI8468615.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            23474..24619
                     /locus_tag="SLE23_001712"
     CDS             23474..24619
                     /locus_tag="SLE23_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8468616.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            25334..27193
                     /gene="ltrA"
                     /locus_tag="SLE23_001713"
     CDS             25334..27193
                     /gene="ltrA"
                     /locus_tag="SLE23_001713"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEI8468617.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
BASE COUNT         9289 a         4756 c         5580 g         7686 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc atttgaaata cccgattggt agcaatggaa
     3661 gatcgtgaat ttctttttaa acgactgagg taacgtagat gaaattgttt taagggtttc
     3721 ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt aataattgac aaaaatgata
     3781 cgcagttcgc aattcttcgt tgtagcttaa cagctcatca acgatttctg tttgactaat
     3841 tggtcgttta aacagtcgat gataatgccg tttgagtggc tcccatgtcg tggaatcttt
     3901 gagtaagagt ttccaatatc gcttgagccg acggtacttc ttctgatttt cagagtgtga
     3961 ggttcgaaaa cgattcatga tctggacacg taattgattg aagctgcgat tgatgtgttg
     4021 gacaatatga aagcggtcag ttacgatctc cgcatttgga aagactgttt taagcaactg
     4081 acaatagctg gcattcatgt ccatcactag gtacttgacc tttaaacggg cctttctagg
     4141 aaagcgcagg aagtattgag ttagtttgta aagtctgcga tcttcaagga tcgtaaatag
     4201 ctgattggtt gtcccatcaa cacaaataaa actcatggaa ccagaaacag aattcattga
     4261 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtggct ggtaatgctt
     4321 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
     4381 tagtttacgt gattgatttt cgtacagttc catgagaatc gcctgcttca gttcctttgt
     4441 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
     4501 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaacat
     4561 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
     4621 ataggaagaa gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
     4681 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
     4741 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
     4801 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
     4861 ccttcgattt tccaccaaca caaaatatta tagaaccctt tttttttgct atatgacagg
     4921 aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc catatctgtt ctatactgga
     4981 taggagaagt ttggaaatat ccagaaaacg aaatcaatcg aggtagccac atgaagaata
     5041 aatggataaa tcgaagtaaa aaaaagaaag taacacaaag atcatcagat aaagtcatcc
     5101 gtctttttcc atcgtataaa gaaggattaa cggcagatca agtcaaggaa cgaatagaaa
     5161 aaggtgcagc aaataattca gtcgatccca cattcaaaac aaatcagcaa atcgtattgg
     5221 aaaacatatt tacgtatttc aatttgatct ttcttatctt agccattttg ctttgtttag
     5281 tagaatccta taagaacttg acttttttac cagttatcat agccaataca ggaatcgcca
     5341 tttttcagga aattcgatcc aaaaagatct tggacgaact aaatgtttta aatacagcaa
     5401 aagtcaatgt catacgagac gggatagaac aaacaataga tatagaagac cttgtaatag
     5461 atgacattgt tattttagag actggatatc aaattccagc agatgcagag gtcgtggaag
     5521 ggaaactgca agttaatgag gctttattga caggcgaagc agatgaaata accaaagaaa
     5581 taggtgatcc attaatgtcc ggcagtttca ttgtttccgg aaaagcttac gcccgattag
     5641 acaaagttgg agcagattcg tatatttccc agctgacagt caaagccaag acaatgggag
     5701 aaggagaaca gtcggagatg attgcttctc ttaatcaatt gatcaaatgg attgggatca
     5761 tcattattcc tatcggtatc ctgctttttt ctcaaagtta cttttttaat ggaaacacga
     5821 tcaaagaaag tgtcgttgca atggaagcag cattgatcgg tatgatacct gaaggactgt
     5881 acttgctgac gacgattgca ttagcattaa gtgcgactaa actagcaaag caaagagttc
     5941 ttttacacaa tatgaaaagc attgagacat tggcaagggt aaatgtcctt tgtgtagata
     6001 aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa aatgatcgtc tctaaaaaac
     6061 aagaaataat cagtcagtca gatcaattgg aagcatgcat tgctgactat gcaaaagcga
     6121 tggcaggaga caatgcaaca atggaagctg ttaaagcata ttttacaaaa accactgatc
     6181 aatcctatca ccatgttatt cctttttctt ctgtccaaaa attcagcagt gtagcgttgg
     6241 cagacaaggt gtatgtttta ggagcgcccg aaatggtttt gcgcgatcaa ttgccggaat
     6301 atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg cgtgttggtc tttggtgtgt
     6361 acgatgggat tcttgaagaa ccagtattga cagaagcagt cacaccatta ggctatattc
     6421 tgattgctaa tcctatcaga aaagaagcaa gagccacatt tgattacttc aaaaaacagc
     6481 aagtagccat caaagtgatt tctggagata atccgctcac cgtatccaat gtagctgtcc
     6541 aagcagggat ttcacatgct gatcagtacg ttgatgcatc taaattatca gaagaagaat
     6601 atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt caagccagaa caaaagaaaa
     6661 tcttcgttca attgataaag cgtaacaata cagtagctat gacaggtgat ggcgtgaatg
     6721 atattctagc catgaaagaa gcagactgca gtatagcgat ggcttccgga aatgaagccg
     6781 ccatgcaggc ctcacaagtg gtcttacttg attctgactt ttcacgcatg ccagaagttg
     6841 ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc agccagcttg tttttagtga
     6901 agaatatttt ctcctttttg ctctcactgt tttcagtgat ctttgctctg acctatcctt
     6961 tagaaccatc acaaatcaca ttgattagtt tgtttactat cggacttcca tctttcttgc
     7021 ttgctctaga agaaaacaaa aagcgaatca gagggaaatt catcatgaat gtgatggaaa
     7081 aagctgtgcc aggtggacta acagatatga tcgtagtcgg tgcgttggtg atctgcgggg
     7141 tgactttgaa tctaaataaa acagatgttt ctacagcatc taccatgctt ttgattgcag
     7201 tagggttcct cgttctctat aaaatctgtt caccgctgaa taaattcaga agtcagatca
     7261 ttcttttctg tgctagcggt aacttttttt cggtcatctt tttgcataag ctgttttcaa
     7321 tcaccggtat ctcagctgta tcacttttgc tgttgagcat tctatttttc tcggcagatt
     7381 cgatttttag gcatttgacc acattggtag aatatttgtt tgaacgtaaa aatgaaaaag
     7441 agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc gatatttaaa cgagaaaatt
     7501 gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca ctcgtgtatc tttcgaagca
     7561 ggatgagtca tccaacttta aaacgcacga gcagttgctc ttttttacat tttcggaatg
     7621 gtaacggtga aagtcgaacc tgttccaaga tgactgtcta cagtaatcgt accattaagg
     7681 agttgcacgt agtcttttac aatcgctaac cctaatccgg tcccgcctga atgtcggctt
     7741 cgcgccttgt ctacgcggta aaaacgctca aagatccgtt cctgatcctc aatgtcgata
     7801 cctataccaa agtcttggac agaaaacgat agatcatctg ttgcctgata gcggataata
     7861 atctcgctgt cgctttttga atattggaca gcattttcaa tcagattttt gataattgga
     7921 taaaggatat ctgttttagt agtaaatggt tcgttctttc caatcaatcg aatcgtcaac
     7981 cgtttctttt cgatgattgg ctgataattt tgaacgattt gctggaaata aggttctgta
     8041 taaattgtct ggatctcgta agaattctcg ccatcttttg acagctggat gatttcccga
     8101 atcagtttat ctaaccggat cgcatctttt tgcatgatct caagaaaaga agtcagagtt
     8161 tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa aaccaatcag tgaagtcaca
     8221 ggagttttta attcgtgaga gacgttgcca acgaaatcct tttgtagctt ttctaaacgt
     8281 cgcactttcg ttaagtcata cgccacccct agaatctgtc cggtaccttc tgaattagta
     8341 aagtagcgca aactcaagtc taatgtctgc cgaccttctg taagggtgat ctcctgatgg
     8401 atcagcggat gctcaggagt cacttgatga atcagctgaa tgagttttgg ctcttgaatg
     8461 acttctgtgt accgctgttc aggttgatag cttaccacgt ttaaatgtag ctgcatcttt
     8521 ggattaagca gtagtaaacg agaatcagca tcatcaatca ggaatacgcc aatcatcagt
     8581 tcgttcagta acgtatataa ttgctcttct gtggtagtac acgcccgata catcttactc
     8641 atttgttcgc tcaacgcatt aatcgtctga tacaattctt cccattgatc gggtgtttgc
     8701 atgattactt ccgcctgatt aggattttgc accatttttt ttagtacggg cagcacggtt
     8761 ttcaatggct ggtttttttg atagatcaga taatagatca ttcctgcaag aacaaggaag
     8821 aaagacagaa agaagaaaaa gacccaacgg cgaaaactct cagttctcgg taaaaaaacg
     8881 cttgtcggtt ctgcgatacg taaaatggct tctaactggc cacttttttt gactggtaat
     8941 gcgacatata aaagatcctc attcaaagta gtacttttgc gcaaagcgct acctaggttc
     9001 ccaccattca atacggcttt gatttcggga cgggagtttc gctgttcatt caatgtttca
     9061 ttgtttgtgt caaataagat ctttccagta gcatccatta aagtaatccg ttcgttcgac
     9121 tgatggacga attcttccaa agcagttttg ttttgcgctg cttggaggtt ttcgacatct
     9181 aattgccgga tcagcagttg tgcttttttt gtcaggtagc tttcttgctg ttccacgatc
     9241 tgctgttgaa aataatggga aatcaattgc cagccaccaa aaaacaaact aactaaaaga
     9301 ataagaaaga agagacgttc ataaattttt ttccatttca tcgtttgggt tcctgaaact
     9361 tatagccaaa tcctctaata gtcaccaagt actttgggtg ttttggatct cgctcgattt
     9421 tttctcgcaa atgactaacg tgtacatcta cgattcggct ttgtcctgcg aagtcaaaat
     9481 tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg gtcttttcgt ttcatgaaat
     9541 aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag atggtcgtct acggtcactt
     9601 gataattggt caaatcagca gtgatttgtc caatcgatag atattcaggc tcagcttcat
     9661 cttttgattg cttacgaggt tcaattcgtc tgaatattgc tttcatacgg gctaatactt
     9721 cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc tatttctagg ccaatgatcc
     9781 gatccacttg gtcatcttta gccgtcagca tcaaaatcgg tgtttcattt ttttcttgac
     9841 gcagccgctg agtgatctcc atgccatcca tcgttggaag catcacatct aaaatgatga
     9901 aatcaaatga ttgttctaat gctaattcta atccttcgcc tccatctgtg gcactggtta
     9961 ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt tacaatagaa ggttcatcat
    10021 caacaactag tatttttttc attcaaatct cctttaaata ggtttcattc tgtttatatt
    10081 ttagcataga atcagtacaa agggctattt tacaaaagaa ataaatggta taataggaag
    10141 gcactttgct gaatagaaag gaagagcagt caatgattgg aatcagtgca tgtttaggcg
    10201 gtctggcctg tcgctatgat ggacagaaaa aagaagtacc agaattgatg gaactagttg
    10261 aaactggaga agctgtcatg gtctgtccag aagtgatcgg cggattacca attcctagag
    10321 atcccgctga aatcattggt ggaaatggat tcgatgtgtg gaaagatcaa gcaaaagtat
    10381 ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa tggcgcgatc aaagcctatc
    10441 aaaaattgca ggaaaaacac attgatctag tcatcatgaa ggaaaaaagc ccttcatgcg
    10501 gaacccattc gatttatgac ggaagttttt ccggaataaa aaaaaatggt gccggagtgg
    10561 ctactgctta ttttattcag caaaaaatga ctgtgctctc tgatgaagaa tggctgaaaa
    10621 ctagaggtga gcagaatgga aatcgaaaag accaatcgaa tgaacgcgct ctttgaattt
    10681 tattcgacct tattgacaga aaaacaaatg aactacatgg aattatatta tgcagatgat
    10741 ttttcattag gtgagatcgc ggaagaatac gaagtaagcc gacaagcagt atatgacaat
    10801 atcaagcgga caagcaagat cttggaggat tatgaaaaaa aactccatct tttttctaat
    10861 tatattgttc gagaacaggt attggaaaat atgactgcat atattacaga taagtacccg
    10921 gaagataaaa aactacttga atatgtacag caaattcaag caatcgaaga ataaataaaa
    10981 ggaatgaaga aaatatggca tttgaaagct taactgaacg tctccagcag gcgatgggaa
    11041 aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa agaaatgatg cgggaaatcc
    11101 gccttgcctt actagaagcc gatgttaact tgcaagtagt caaagatttt actaagcgcg
    11161 tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt atcacctgca caacaaatcg
    11221 taaaaatcgt tgatgaagaa ttgacgatca cacttggttc tgaaacagca gagttaaata
    11281 aatcaccaaa aataccaact gttatcatga tggctggtct tcaaggggca ggtaaaacga
    11341 cctttactgg taaattagcc aattatttaa agaaaaatga aaatgctcgt ccgctcctaa
    11401 tcgcagggga cgtatatcga ccagctgcga tcgaccaatt gaaagtatta ggtcaacagc
    11461 tagacgttcc tgtatttgat atgggaactg aagtcagccc ggtagagatc gtccgtcaag
    11521 ggatggagtt agcaaaagaa aagaaaaacg actatgtatt gatcgatacg gcaggacgtc
    11581 tgcatatcga tgaaacattg atggatgagt tgaaacaaat caaagaattg acgcaaccaa
    11641 atgagatttt gcttgttgtc gatgccatga ctggtcaaga tgccgtcaac gtagctgata
    11701 gcttcaacca gcaattaggt attacagggg tcgtcatcac taaacttgat ggggatactc
    11761 gaggcggggc agcactatcg atccgctcag tgacaggcgc accaatcaaa ttcatcggtt
    11821 ctggtgaaaa attgactgac ttagaagtat tccacccaga tcgtatggct agccgtatcc
    11881 ttggtatggg ggatatgctg acattgattg aaaaagcgca gcaagactac gacgagaaaa
    11941 aagcggaaga acttgcacag aaaatgcggg aaaattcatt cgatttcaat gactttattg
    12001 aacagcttga tcaagtgatg ggtatgggcc cactggaaga tctaatcaaa atgatcccag
    12061 gaatgaatca agtccctgga atcgaaaacg tcaaggtaga tccaaaagat gttgaacgca
    12121 aaaaagcgat ggtttattct atgacgccag cagaaagagc aaatcctgat ctgttgaacc
    12181 caagccgtcg tcgccgaatt gctgccggtt ctggaaacag tgttgttgaa gtgaatcgaa
    12241 tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca aatgtccaaa ggggatatga
    12301 acatcccagg tatggaccaa atgtttggtt caggcgtcaa aggaaaacta ggcaaaatgg
    12361 cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa aaaacggaaa taagatgaaa
    12421 aaaacagctt cggtacagac tgaaaatgtc tactgccgga gcttttctat cagcaatttt
    12481 tattctttac taatacaatt actctaaacg aagaggtggc acagatgaga tgtccgtgga
    12541 gtgaacaaac agaaagtatg cggcaatatc atgatactgt ctggggtgtt cctgaatatg
    12601 atgaccaaaa gctgttccga aaattgatgc ttgatattaa tcaagccgga ttgagctggc
    12661 agacgatttt aaataaaagt gaagcattcg atgaagcata tgatcgattc gatatcaaaa
    12721 aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat ggaaaacaaa ggaattattc
    12781 gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa agcagtcttg aaaattcaag
    12841 aagaaatcgg cagtttttca gagtatcttt ggtcgttttc taatggaaaa atcgttgatt
    12901 cttcttatca ttcacaagaa gaagtcccaa caacaagtcc tctttcagat gaattagcaa
    12961 aagatctaaa gaaaagagga tttaaattta tcggaagcac aacaatctat gcttttttag
    13021 aagctgtcgg gatcatcaat gatcaccttg acagttgttt ccgcaaagaa gaggtcgtac
    13081 gtatcggcag aaagggcgaa taaagcatgc gaaaaatcat attttatggt gctataagtt
    13141 tagatggcta tttggcaacg aaaacggatg atcttcaatg gctttttgac actccaacag
    13201 gtaagcaaac tacttatgaa gctttttatg aaacaatcga tacgaccatc atgggcagaa
    13261 aaacttatca ggaagcaaaa aaatatttgg agaccgaagc aatttatcca gagaaaaaga
    13321 atttcgtttt ttccacccac gcacaattac aattgccaga tgctgaggtc gtaaacgaag
    13381 atcctgttgc ttttctaaaa aatctacaaa tgacagaagg aaaagatatc tgggttgtgg
    13441 gtggcggtcg attgatcaaa ccgctattgg aacatcaaat gattgatgaa tggtatatcc
    13501 agattacccc tgtattatta ggggacggga ttcctttatt ccaaaaagga acatatgaag
    13561 cgcgttttga aatgctagac acgacacgat tcggtgaatt tatcgaattg cattatgtac
    13621 gaaagtagaa gtaaataaaa taaaaaaggc aactatatgc agaaatgtcc tgtacatagt
    13681 tgcctttttt attaccgtta tgctttttac tctgttaatt tgttagaaaa atctagatac
    13741 gcatctaaaa tcgtttggaa gaaacttaat gttccttcaa cgatattacc attttcatca
    13801 attagattcg caacgtttcc gatatatgct tccggttgct gcaaggttgg cacattcaaa
    13861 aagacaagtg attggcgtag atggtggttt gcgccaaagc cgccgatccc acctggtgat
    13921 gcagtaacga ctaaacctgg tttatgatcc caaacactgt gtccataagg tcttgagcct
    13981 acatctaaag catttttcaa tactgctggc acagaacggt tgtattcagg agtaacgaaa
    14041 acgacaccgt ctagtcccct cacttcctca cgaaaacgag tccattcagc aggagcctgt
    14101 tctggagttt cgagatcctc attgtaaaat ggcagatcat cgatttttac aaatacactt
    14161 tcgtaccctt caggaagcaa tttcgcaaaa gcttctgcta cttttttgtt gtaagaatct
    14221 tttcttaaac taccaataaa aaatccaatt ttttttgtca tacgattttt cctccttcaa
    14281 actatctata ataatcttac aaaagataag taactggagc aaataaaaac acttactgac
    14341 aaaagctaca tagaagatag attacttatt tttaacaaaa aagaagtcta aaatcttcta
    14401 ttttctaaaa aaaatcgaat ttaatcaagc tgtaaagaaa aaaagcttta cagggtaaaa
    14461 aaaaactgtt acactacatc ttgtgaataa aacaatggag gtggaaataa ataatggcag
    14521 ttaaaatccg tttaaaacgt atgggttcta aaaagagtcc gttttaccgt atcgtcgtag
    14581 ctgattcacg ttctcctcgt gatggacgtt tcatcgaaac tgtaggtact tacaatcctt
    14641 tgaaagaccc tgcagaagta gttttaaaag aagacttagt tcttgactgg ttatcaaaag
    14701 gtgcacaacc ttctgacact gtacgtaaca tcctttcaaa agaaggcgtt atgcaaaaac
    14761 accacgaagc taaattctca aagaaataag gtgaccggat atgaaagatt taagcgactt
    14821 agtcttaaca atcgttcgtc cgctagtcac ttatcctgat caagtcaagt tagacgtcgt
    14881 agagtcgaaa gacttttacg agtacaatct aacagtggct cctgaagata ttggccgtat
    14941 cattggaaaa caagggcgtg ttgctaaagc aatccgcaca atcgtttacg gtgttcggat
    15001 caatgcaccg aaaaaagtgc gtttgaatat catcgatgat aaggaaaagt aaataaacgt
    15061 gctgtactcg aattttcgag tgcagctttt ttgttttttt tattaattga agaaatgatt
    15121 atttggcaaa acaagcaaga aagcgtatcc ttataggagg agggagtgaa cagccaatga
    15181 gaaagaaaat gttatttatt ccatttgctc tattgttaag cgcttgtagt tcggttactc
    15241 aagaatcaga caatacacat ctatcaagca gtatatctga aactgttacc agtccagaaa
    15301 aaagtagtac caaaacggct tccaccactg aacaaacaat ggctacctca aataatgaga
    15361 aaaagactgc tttagaccag ttgaaagaac aacagccaaa tgttcccatg cctctagatg
    15421 taccagtctc ttcaggctat ctcaatatcg cagcgacaca tacaaagcaa ggttattcta
    15481 ttttatatta cagaacagat cgtcccctcg ggttgaatgc tgacgaattg aatcaagaaa
    15541 cgcctattgc aacctatcta tatcaatatg ggtttgcttc tagtcaagaa acaatccaag
    15601 ttttgcagcc atttgagatc gacacaaatg gtcagcaagt ggacttaggt tctcgaatca
    15661 cagggtatca gcaaggtgca gcaggttcaa gttttcttga atggcaagaa ggaaactggc
    15721 gtattcgaat ccgtgggaat aatatagaag gccaagatcc cttactatta gctaaagaaa
    15781 tcgtagctta tttggaagaa aacagtctac cagcacctga acaatttggt aaaattactg
    15841 ttgatatggg tgatacgacg aatcgagccg tagaagtaag ctggcaagaa ccgaaaaatg
    15901 cctatacgat cactcatcaa gatcctatgt ctgcgttgaa gatggcagtt tctatgaaga
    15961 ggttgtgaaa tcagcgcgct gatctgagcc catcatttaa ctccaagtca caggaagtaa
    16021 tcaaaaatag cacgccgcat ttttgcataa ttttggctta ataccttaaa agaaaactag
    16081 aattgcctct tcacacatgc taaaataaaa cagacaaaaa agaaatgggg atataagttg
    16141 actgaatact tgaatgtagg aaaaatcgta aacacacaag gtatcaaagg cgaagtccgt
    16201 gttatctcaa caacggattt cccagaagaa cgttacaaaa aaggaacggt gctaacacta
    16261 ttccaagacg gaaaagcacc tgtggaatta acagtcaaaa gtcatcgcaa acataaaaat
    16321 tttgacttat tgagttttga aggacatcct tctatcaatg atgtggaaaa atatcgggat
    16381 ggcatattaa aagtgtcaaa agacaactct gtagatctag ctgaaaatga attctattac
    16441 catgagatca tcggtctgca tgtattagaa gatggaactg agttaggtaa agtaaaagaa
    16501 atcttgtcac caggtgccaa tgatgtttgg gtcgttcaac gtccgaaaaa agctgatata
    16561 ttgcttccat atatcgcttc tgtcgtcaaa gaagtcgatt tagaagctgg agtggtccgt
    16621 gtagaaattc cagaaggact gattgacgat gaagattgat gtattgactt tatttccaag
    16681 aatgtttgaa ggtcctatgg gggaatccat catcggtaag gctgtagata aaggattatt
    16741 agatatcaat atctctaact tccgcgatta ttcagataac aaacatcaga cagtagatga
    16801 ttatccatac ggcggtggag caggtatgct gctcaaagtc cagcccatct atgataacat
    16861 ccaagccatt gaaaaagctg caccggatgt caaaaaaaga gtaattcttc ttgacccagc
    16921 tggtaaacga ttcgatcaga aaatggcaga agaattttca caagaagaac acttagtatt
    16981 catttgtggt cattatgagg gatatgatga acgtatccgc acattagtga cagatgaagt
    17041 ttccttagga gattatgtcc ttactggggg agaattaggt gcgatggtca tgatcgatgc
    17101 aacagttcgg cttttgccag atgtgttagg gaatcagact tcagctcaaa cggattctta
    17161 ttcaaccggt ttattggaac atccccaata tactcgcccg gcagaatata aagggatgaa
    17221 agtaccagaa gtattgacaa atggaaatca taaattgatt gaagaatggc aattaaaaga
    17281 atcactaaga aggacctatc aacgtcggcc tgatcttttg gaaacacttg aatggacacc
    17341 tcaaatgacg aaatttttag aagaaatcaa gaaagaagaa caagaaaaaa cagcagatga
    17401 agccaagtga ctttttctaa aatcttcttt acagtaggtt gataatatgt tagtatttta
    17461 tggtgagtgc aaaagcactt aactattacg atattccgct gtgagaaaag ctcataagaa
    17521 tatttggaat aaggagaaga aaaccatgaa tccattaatc gaagaattaa caaaagaaca
    17581 attacgttct gacatcccag cgttccgccc tggtgacact gtgcgtgttc acgcaaaagt
    17641 tgttgaaggt actcgtgaac gtatccagtt atttgaaggt gttgttatca aacgccgcgg
    17701 tgctggaatc agcgaaactt atacagtacg taaagtttct aacggagtgg gcgttgaacg
    17761 tacattccca ttgcatacac cacgtgttgc aaaaatcgaa gtagttcgct acggtaaagt
    17821 acgtcgtgca aaattgtact acctacgtgc attacacgga aaagctgctc gtatcaaaga
    17881 aatcagaaga taaacacgga aaacttcctt ggaaatctga aatttgtgaa aagtccttgt
    17941 atatcaaggg ctttttcttt tttctctatc acagttttaa gccatttttg gctgttttgg
    18001 accatttttc aatcatattc ccttaaaaat tgtcctagat tgtccgacat tgactatcag
    18061 tgtcgtcaaa atagggcaaa atttagtagt cagcttgacg acaaatataa tacgaaaaat
    18121 accaaaacat ttaccgaatt tagcaacttt tgaacccaag tttctcaaag ggtcagctat
    18181 tagcaaaaaa gacaaaacat gtacttttct actaaaaagt tgatgtgata ggcttctatc
    18241 taaataacta ttaggagttt ttatcgtgaa gcaaaatgat ggacgtatca tttggaaaaa
    18301 tcaaagtgag ttaaaactga ttttaacaat taatgaattc atcgaaaaac acggaattac
    18361 atctagccgt caataccaga aaaagctatc agaaaatcca aattctgcac caagtatgtg
    18421 gttcattaac aaaaaatatg gatcatggga gaatttattg attagtatag gacgagaaaa
    18481 tactgggtat ggaaaatggg ctagaatgtc agaacaagaa ttattggaaa tagtagaagc
    18541 ctttattaag tgcgagaaga taacctctca acgaatgtac gaacaaaaat cagtagggaa
    18601 gaatattcct tcacttagta ccattaaaaa gatgttagga gatatacgtc cactttttaa
    18661 agaaaaaaat gatggatctc gatttactga tttcgaactg ctgttagaac taaaaaatga
    18721 aataatccga ttaaaactac aggatgattt atcaatgaca aagtttcgaa aactagttca
    18781 atccccaaaa ctaccatcag ttgatacaat tatgaaaaga acgaacaaaa attgggagga
    18841 attgatggca gagattggat ttgattatcg aagaatcaaa atttataagc agagaaacaa
    18901 cctatccaag acaaagaaaa ctaaatagta tcactctaaa tcagacgttc aaaattaaaa
    18961 tttggacgtc ttttttatta cccaaaaacg aaaggagatt tattttatga aaaagccaag
    19021 atttaagaat tggcgtttgc tcgcaacact gagtctatta tgccaaacaa ttggtggatc
    19081 gcttggccca acgattgcct ttgctgatga aattactcat ccacaaacgg taactgtgga
    19141 attggatttg gctcaccagt atgctgtcga aggtacattt agcgatggtc gtcccatgtc
    19201 agaagttacc gttccgcact atgcagttta caatggtgtg aagcaagata ttttctgtat
    19261 tgagccaggg gtgccgattt acaatgagtt cactcctggt tatgagaaaa atccattgcc
    19321 tgatatgtcg gagaaagcga aattagtttc cgttttatgg aaggaagctg gtacggatgt
    19381 ggatacacat attgtggccc agaagatgat ttggcaagaa gttaatggct acacgcttca
    19441 ctcaattaaa cgttctgatg gtagtgcagt aaatatcgca gccattgagt caaaaatcaa
    19501 tcaagccatt gcggattatc aaaagaaacc aagcttccat aactccacag tgaaaaccgt
    19561 gttaggtcaa tcgactactg tgacagatac gaacggcttg aatttatcgg agtttgatga
    19621 agttgtcgag aatatcgcaa atattgatta tcgtgtgaac ggcaatcaac tagtgattac
    19681 tccaaatgcc aattcaaaag agagtggtga attaacccta aagaagtcag ctaatacagg
    19741 aacaccggta gcttataaaa tggctggtca acaaactttg atggcggggg caattgataa
    19801 gcccaatacc tacacaatca aaattgatgt ggaaactgag ggttctttga agattaaaaa
    19861 agtcgataaa gaaacaggaa atgttgtacc gggaaccgtt ttccatttag actttggaaa
    19921 aacattacct gcaaaagacg tgaccaccga taaagaaggc attgcgacat tggatgagat
    19981 tcctcatggc gcgaaagtaa ccattactga aaaatcagtg ccagctcctt atacgattga
    20041 cactacacca atcaccgcaa ccattaaatc tggtgagact atttctgtga cttcaaaaaa
    20101 tactcgcgaa aaaggtcaaa tcattttgaa taaaatgggg gtggaaacag gaactgatct
    20161 ttggaacgac aaatactcat tagccggaaa tacgtttgcc attcgcaaag acagtccaac
    20221 cggtgaaatt gtccaagaaa tgaccacgga tgaaaaaggt catgcggaaa caccaaaaga
    20281 gattgccaat gcgttggaat tgggaaccta ttatgtgacc gaaaccaaag ctagtaatgg
    20341 ctttgtgaat acctttaaac cagtaaaagt cgaattgaac tatgtcaatc aaaccgtggc
    20401 tcttgttacc agtaacgtaa aagggcaaaa ccaagaaatc actggtgaaa ccactttgac
    20461 aaaagaagac aaagataccg gtaatgaaac tcaaggtaaa gctgagttta aaggagctga
    20521 atatactctc tttactgcaa aagatggtca agcggtcaaa tggagtgagg cttttaaacc
    20581 agagttagtg aagggaacga aagcttctga tgaaacggtg actttgactt tagatgaaaa
    20641 gaatcaagtt gctgttaaac acttagcgat taatgagtat tactggcaag aaaccaaagc
    20701 acctgaagga tataccttgg atgaaacaaa gtaccctgtt tccatcaaaa aggtggatga
    20761 taacgaaaaa aatgccgtga ttacccgaga tgttacggca aaagaacaag tcattcgctt
    20821 tggctttgat ttctttaaat ttgctggatc agctgctggg actgccgaaa ctggcttcaa
    20881 tgatctgacc tttaaagtat cgccattgga aggaaccagt gagattacag gtgccgaaga
    20941 tgaagcaatt acagcttata acgagcaact aggttttgat ggctatggca agtttgaaaa
    21001 tcttccttat ggggattatt tacttgaaga agtagaggct ccagaaggat ttcaaaaaat
    21061 tacgccatta gaaatccgtt ctacttttaa agaaaataaa gcggattaca ctaagagtga
    21121 atacattttt acgattaccg aaaaaggaca aaaacaacca attaaaacgg tgaccgttcc
    21181 ttacgagaaa ctgacgaata aagcattttc tgttagcttg aatcgtttga tgctctatga
    21241 tttacctgaa gaagaagata gcttaacttc tcttgggact tggaaagacg gaggcaaaga
    21301 attgacagac cttgattcta ccgagctagt tgataaattg agctataact tgcatgaaat
    21361 caaagaagac tggtatgtgg tagcgcaagc cattgatgtg gaagcgacaa aagctgccca
    21421 agaaaaagat gaaaaagcca aaccagtggt aattgccgaa acaaccgcaa cgttggcgaa
    21481 taaagagaaa acaggaactt ggaaaatttt gcataaatta accgcagaac aagttttgga
    21541 taaaaccatc gtcttattca actatgtgta tgaaaacaag aaaccctatg aagcaggtga
    21601 tgatccagta gcgaaagatg ctagcttgaa caatcaagcc caaactgtca attgtacggt
    21661 ggaacgccat gtttccatcc aaacaaaagc ccacctagaa gatggttcgc aaacctttac
    21721 tcatggggat gtggtggata tgttcgatga tgtgtcgatt acccatgatg tactggatgg
    21781 ctcaaaagaa gcttttgaaa caattctgta tgcattactt ccggataata cgaccaaaga
    21841 aatttggaaa tctggcaaaa ttgattatga agtgaatgac aaagaattca ctaaaaccgt
    21901 acttgcggaa aaagtggaca caagtaaata tccagaaggt acaagtttta ccttcaaaga
    21961 aattaactat ggcaaagacg gaaacatcaa tgggaaacac aatgaggatc taaaagaaaa
    22021 aactcaaact ttaacaccta aaaaagttcc gacaacacca agtgcaccag aacaaccgga
    22081 aataccaact gttccaagtg actctcaaga atctagtcct acagtaaaga cattcccaca
    22141 aacaggggag aaaaattcta atgttctgct gtttattggg tttaccttga tctttgcgac
    22201 tgctgggtat tatttctgga atcgccgaaa ctaaggtgat gtgatgaaac aactaaatag
    22261 gaaaaaccaa cgtgcgcgac cgcctcctaa aaaaagtggt cgcgctattt ttgtatccaa
    22321 aactaaaaat gaaaagagga aaagaagatg gaattgaaat ttgttgtgcc agatatggcc
    22381 gaaacctttg gaaagataag gtatgccggc gaaggcgaag ttttaactga aggatatggg
    22441 cggaatacta cagtaattgg tcgtagttat catttgtatt ccagtaagca acgagccgat
    22501 gatattgaag tggtggtagc tgcggaagcc ggcgaaaagg attttgatca agatcaacca
    22561 ctaaaagccg tgaatcccca tttggttgcc aaaggctatg agattgagaa tcgtgggttt
    22621 accgactacg tgttgtatgt cgatgattta gtgaaagcat aggaggaaaa gaagatgaga
    22681 ttaacagaag gtattgttgt agattcagga ctaacgtttg ggaaattacg attttccgca
    22741 ttacgccgag aagtacggaa gcaaaatgag gatggaacgg ttagtaacga ggtaaaagaa
    22801 cggacttata atttgaaatc ctctgcgcaa ggtcgaatga tccaagttag tatcccagca
    22861 aatgtaccct tacgcgagtt tgcctatgac gcagaggtag agttggtcaa tccaatcatg
    22921 gatacggtcg ccaattatgt tttccgagaa ggaactactg tcaattggtt cattaaggcc
    22981 gatgatttag tcttgaaacg acaaccagat cagggaaatt ctacaaacca aaatgaagga
    23041 aagaaatagg tgaagcgtat ggaaattaat gttgaacata ttttagattg tctcgatcaa
    23101 tatggaaaag gtgagctaac ggaggaacaa ctcactaaag cattaaccta tgatgaaaaa
    23161 atgtttctga ttatgcatca agggttactg gaagtaggta acgatgccga agaagatttt
    23221 gatgtactga attggttagg ggaagaagag tccttcttta tggttatcga agtaaatgaa
    23281 agtctatgtc gagaagccga aaccgtattg gaagaaattg gtgtggaaat gccggatgcc
    23341 attgaagttt ttttaaagca actagtggaa acgaaacaac tccctatagc agtaaatgac
    23401 tagcataact gcttgaaatt ggatcaatga aatcctatga agcttttttc gattggaggt
    23461 ggaaaccata aaaatgtaca aagggcatcg tatacgggca ggagatcagc acttggttta
    23521 tcactttgtt cttggctggc tactcgctct gttcatcggt tggatgagcg tcttttattt
    23581 tcaagagctt agacaatttg atatttctaa gctatcactt tctactatag aaatcgttcg
    23641 ttctataaaa gatttaatct atttgctagg aagtctcgtt ctttcaggaa gcacgatgtt
    23701 gctttatata cacttttttc aggatcattg gcgcagtttg tggcatcgac aaaagctagc
    23761 ccggatgatt ctagaaaatc attggtacga agtaaaacaa actcagagtg aaggattttt
    23821 caaagacctc aatagtagtc gaaccaaaga gacaatcagt tacttcccca aaatctatta
    23881 ccgtatgaag gatggtttac tttctattcg cgttcaaatt tcactgggaa aatatcaaga
    23941 tcagctttta aagctggaaa agaagttaga aagtggtcta tattgtgaac tagtagaaaa
    24001 ggaactcaaa gactcctatg tggagtacac tttactgtat gatataattg ccaatcgaat
    24061 tgggatagac gaagtagtgg cagaaagtgg ggctttgcga ttgatgaaaa atcaagtatg
    24121 ggcttatgat tctttacctc atatgttaat cgctggcggc acaggtggtg ggaagactta
    24181 ctttttactc actatcatcg aggctttatt aaaatctgat gccgagcttt ttgttcttga
    24241 tcccaaaaat gcggacttag ccgatttagg tacggtaatg cctcatgtct attcccaaaa
    24301 ggaggaaatt tctgcttgtg tggaagattt ctatgagcgc atgatgactc gtagcaaggc
    24361 aatgaaagaa atgcccaact acaaaacagg agagaattat gcgtttcttg gacttccacc
    24421 aaacttttta atctttgatg aatacgtggt ttatatggaa atgttaacga cgaaggaaag
    24481 tgcggtgatt ttgaataagc tcaaacaaat cgtgatgtta ggtcgtcaat ctggtttctt
    24541 tctgattcta gcttgtcaaa gaccggatgc gaaatattta ggagacggga ttcgcgatca
    24601 atgtgcgaca tgtttctaac tgaaaaggtt aggcacttaa aagaagaaaa cataagtttc
    24661 cttttaagga gaactgatat tttgagcagt ggaatgatgg ggtaacgccc tgaaacgctc
    24721 ccttaatact ccgactggct gtttaacata tagctgttag atggtcagaa gctcggtgaa
    24781 gtcggctgaa agttaccgta aatatgataa attcatatac gaaagttgtt cagaggtgaa
    24841 tgatgtaacc tataggtcgg aggtctataa aatactcacg gtgagaatgt aagtaatact
    24901 actgacgaac ttgcgaatga aagaatctat acacggactg tatagaaatg tacaggattc
    24961 taccgtatca acggaacaga atgtatgttg tggtttagta agattattgg ttatgaacaa
    25021 ccatgcaatg ttacaggcat tggaaatata caggttcaaa gcaagcacct aaaagtatat
    25081 ataaagataa aaatatcgaa acatgggaag ctggcaatgt ggaggaaact atattccatt
    25141 gaaacatttg tgacgaagaa taataagcac atttatgcca gtgaaagtgg tggcacagta
    25201 ccaatgagga tatagaaata tatcggagga atagccacta gtcaaaagaa atcgttaatt
    25261 aaatgatgta tttcatagaa tcgagtaaga caaaataaac actacaacct aagtaaacaa
    25321 aggtagtggt gctatgaata aagtaaaaac aaataaaaca cttcgtcata gtgaatacta
    25381 tggcatgaca caaatatttg atgaactgta tgtaaaaagt gataaaaaag aagtttttac
    25441 agagctcatg acaattatta tgagtgatga aaatattcga ctagcataca gaaatatcaa
    25501 gaataacaag ggcagttata cagcgagtac cgataagaaa agtattcgag acattaaaac
    25561 actgtcagaa gatacctttc taactgaggt taaagttctt tttcgctgtt acaaaccacg
    25621 agcagttaga cgtgtagaaa ttcccaaacc aaatggaaaa acacgccctc tgggcattcc
    25681 atcaatctgg gataggttaa tacaacagtg tattttacaa gtcttagaac cgatatgcga
    25741 agctaaattt cacaattata gttatggatt tcgaccaaac cgttccacac atcatgcgat
    25801 tgctacctgc aatcgactgg caaatagggg gaagctacac tttgtagtag atgttgatat
    25861 taaaggattc tttgataatg tcaatcactc taaacttttg cgtcaaatgt ggacgattgg
    25921 aatccgtgat aaatggctat taggtattat tcgatccatg ctaaatgctc ctatagtcct
    25981 accaaccggt aaagtcgaac accctaaaaa aggtgtacct caaggtggtg tcctatcccc
    26041 tttactatct aatatcatat tgaatgaatt agattggtgg gttgcttcac aatggcaaaa
    26101 taccacgatt gagacagaaa agattatgga taggcgagat aaaggcaaag gcattgataa
    26161 gactaatcag tatcgggcat taagacgaac aaacttaaaa gaaatataca ttgttcggta
    26221 tgctgacgac ttcaaaatct tttgtagaaa acgaagtcat gcagataaaa tatttcacgc
    26281 aacgaaaatg tggcttaaag aacggttatc acttgaaatt agcgaagaaa aatccaaaat
    26341 tgtcaatctc aaaaaaggta aatcagaata tctaggattt gaattaaagc taatcaagaa
    26401 aggtaaaaaa tacgtagtcg aaagtcatat gagcaaaaaa tcaatgacaa gagttaaaat
    26461 ccaattaaag aaacaattac gtaaagttgc cagaccgaag aatcattgcg aacaagcaaa
    26521 agaaattgga ttatataatt ctatggtgat tggaatccat caatattatg gaattgcaac
    26581 ctgtgtaaat ctcgattgca gtaaaatagc ctatacacta aaaccgttca tcaatcacaa
    26641 actgccgaca aagaaacatg gaaagatatt aaatacattt atcaaatcga agtatggaaa
    26701 aagtaaagaa atgcgatggt tgaataatgt gccaattgta ccgctcaact atgttcagtt
    26761 tagacttgct gtccccctat cagagggaac ttgcaagtac actgaaagtg gacgaagcaa
    26821 gatacacagt aaattaaaat tagacctagc ccttttactt cacatgatga gaaatagtaa
    26881 ttatgaaaga agtattgaat ttgtggataa cagaatatct aaatattctg ctcaaaaggg
    26941 aaaatgtgct atcacgggta aatttctcga atacgaagaa atccattgcc accatatcgt
    27001 accagtaaaa caacagggta cagacaaata cagcaacctc attattattc acaaaaatgt
    27061 tcacgcatta gtccatgcta tcgaagaaaa aatcatacac aaatacctga atgtattaaa
    27121 tctaaccaat gaacaaatag aaaaactaaa tgaattacgt gtcaaagctg gtaatagtgt
    27181 tttaacagtt taacttgaaa aatatatcat acttaacatt cttttgatgg aacgccgtat
    27241 gaagtgaaag tttcatgtac ggtgtgaagc gggggaaaat ctggagatga catcaaagga
    27301 ttacctatcg c
//
LOCUS       DARPZJ010000033        26902 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.034, whole genome shotgun sequence.
ACCESSION   DARPZJ010000033 DARPZJ010000000
VERSION     DARPZJ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.034"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(40..1146)
                     /locus_tag="SLE23_001714"
     CDS             complement(40..1146)
                     /locus_tag="SLE23_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEI8468618.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRTRYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            1356..2357
                     /gene="ccpA"
                     /locus_tag="SLE23_001715"
     CDS             1356..2357
                     /gene="ccpA"
                     /locus_tag="SLE23_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEI8468619.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLADRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEGFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(2694..5039)
                     /locus_tag="SLE23_001716"
     CDS             complement(2694..5039)
                     /locus_tag="SLE23_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEI8468620.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            5318..6220
                     /locus_tag="SLE23_001717"
     CDS             5318..6220
                     /locus_tag="SLE23_001717"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HEI8468621.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            6433..8208
                     /locus_tag="SLE23_001718"
     CDS             6433..8208
                     /locus_tag="SLE23_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HEI8468622.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(8274..9860)
                     /locus_tag="SLE23_001719"
     CDS             complement(8274..9860)
                     /locus_tag="SLE23_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HEI8468623.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQEMVEEIE"
     gene            10111..10335
                     /locus_tag="SLE23_001720"
     CDS             10111..10335
                     /locus_tag="SLE23_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEI8468624.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            10476..12227
                     /locus_tag="SLE23_001721"
     CDS             10476..12227
                     /locus_tag="SLE23_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8468625.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIISAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            12227..14011
                     /locus_tag="SLE23_001722"
     CDS             12227..14011
                     /locus_tag="SLE23_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468626.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            14337..15188
                     /locus_tag="SLE23_001723"
     CDS             14337..15188
                     /locus_tag="SLE23_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8468627.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVVQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            15285..17165
                     /locus_tag="SLE23_001724"
     CDS             15285..17165
                     /locus_tag="SLE23_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8468628.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEVEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVPFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAISGIYLMASGTISYTMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(17205..18107)
                     /locus_tag="SLE23_001725"
     CDS             complement(17205..18107)
                     /locus_tag="SLE23_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8468629.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENKVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            18338..19741
                     /locus_tag="SLE23_001726"
     CDS             18338..19741
                     /locus_tag="SLE23_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEI8468630.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALNDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            19741..21174
                     /locus_tag="SLE23_001727"
     CDS             19741..21174
                     /locus_tag="SLE23_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEI8468631.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            21319..22245
                     /gene="trxB"
                     /locus_tag="SLE23_001728"
     CDS             21319..22245
                     /gene="trxB"
                     /locus_tag="SLE23_001728"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEI8468632.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            22459..24186
                     /locus_tag="SLE23_001729"
     CDS             22459..24186
                     /locus_tag="SLE23_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEI8468633.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            24201..24551
                     /locus_tag="SLE23_001730"
     CDS             24201..24551
                     /locus_tag="SLE23_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEI8468634.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(24643..25503)
                     /locus_tag="SLE23_001731"
     CDS             complement(24643..25503)
                     /locus_tag="SLE23_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HEI8468635.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            25595..26023
                     /locus_tag="SLE23_001732"
     CDS             25595..26023
                     /locus_tag="SLE23_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEI8468636.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            26185..26361
                     /locus_tag="SLE23_001733"
     CDS             26185..26361
                     /locus_tag="SLE23_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEI8468637.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            26388..26834
                     /locus_tag="SLE23_001734"
     CDS             26388..26834
                     /locus_tag="SLE23_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HEI8468638.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         8514 a         4797 c         5747 g         7844 t
ORIGIN      
        1 aaaaaggtgg gagcggacta gctctcacct tttttactct tatttttcta aaacaagtaa
       61 ttcttttggt gtagtcgtga atggcacaca gccatcgctt gtcacatata cacagtcttc
      121 gatacgtacc cctacttttt caggaatata gattcctggt tcaagagaga agcacatccc
      181 ttcttcgatt actaagtcat ttccttctac aagggaaggg aattcgtgga cggttgttcc
      241 gatcccgtga cctaaacggt gattgaaata ttcgccgtag ccatagctgt tgatcacgtt
      301 tcgtgcgatt tgatcaagtt cacctgctgt cacacctgga cggacggctt cttgtgcggc
      361 aagctgtgct tcaagagtga tgttgtagat tttttcttgg aagtcggttg gtttttgata
      421 agcaattgta cgagtagcat cactgcaata gccattccaa acaacgccaa gatcgaataa
      481 cacaagttca ttcggtgaaa tcttcgtatt tcctggtgta ccatgagggc ttgcagcatt
      541 tgctcctgca aggactaatg tgtcgaaaga catttgtgaa acaccttgtt ttttcaattg
      601 gtattcaatt tctgcaatga tcgcttgttc agtcacgcct tctttcactg ctttaaagcc
      661 aatctcaaat gcaacatcgg cccatttacc agcttcgatc agtttgtctt tttcctctag
      721 agttttgatc agttgtagac gttggatgat ggaagttaga tcagtgtaag aatccgttcc
      781 cgtcaagata tcagagatag catcgaagcg ctcgacagtc aaggcgttct tttcaatccc
      841 tacattgcca ggctgaccat agcgagtacg aagttctttt ccgatgatct cccaagggtt
      901 ttcgctgtct aaatagccgc ggacatcata cgcccaacta ctgttttgag catcttcaac
      961 ttccaaagca ggagtgaaaa ggaaaggatc ttgttcaaga gggataaaaa gagctagtac
     1021 acgctcatga ggatcacttt cgtatccgga aaagtaagcg atgtggccag ggtcgctgat
     1081 ataagccaat tcgacttggt gttgtgccat ccattgacgt agttcattga tttttacgtt
     1141 attcatttgg caacctactt tctaaattaa ttttgtattc aataattgta ccactgattt
     1201 attaaaagac caacgttcta aaaactgaaa aaagtaaaaa ttttcatgaa aacagagata
     1261 aaacggttgc aattcttgag attatttgat attctatttt agaaatgtaa gacgtatttt
     1321 cagaaaacat ataaaatatg aatgggagaa cacaaatgga aaagcaaaca atcactatct
     1381 atgatgtagc gagagaggca aatgtttcga tggctactgt ttcacgtgtc gtaaatggca
     1441 atccaaacgt taaaccagca acaagaaaaa aagtcttgga agtcatcgat cgcttggatt
     1501 atcgtccaaa cgcagttgcg cgtggcttgg caagtaagaa aacaacaaca gttggggtaa
     1561 tcatccctga tgtcagcaat atgttctttg cttctttagc acgtggtatc gatgatgtgg
     1621 caacaatgta caaatacaat attatcttag caaattcaga tggcaacgac caaaaagaag
     1681 tcaatgtatt gaataactta ctggctaagc aagtggacgg cgtgatcttc atgggtcacc
     1741 atatcacaga cgaaatccgt ggagaatttt cacgttcaaa aactcctgtt gtattagctg
     1801 gctctattga tccagatgaa caagtaggta gcgtaaacat tgattatgta tccgcaacaa
     1861 aagatgcagt aaataaattg gcaaaaagcg gcaataaaaa aatcgctttt gtcagtggtg
     1921 cgttgatcga tcctatcaat ggacaaaatc gtctgaaagg ctataaagaa gcattaagcg
     1981 aaaataacct accatatagc gaaggattga tctttgaagc acaatacaac ttcaaagatg
     2041 gtctatctct agccgatcgg atccataata gcggtgcaac agctgtctat gtttcagatg
     2101 atgaattagc catcggtatt ttggatggtt tattagatcg tggcgtgaaa gtaccggaag
     2161 gattcgaaat catcacaagt aacaattcac tactgacaga agtagctcgt cctcgtttaa
     2221 caagtatcac acaaccatta tacgatttag gggcggtatc tatgcgccta ttgacgaaaa
     2281 tgatgaataa agaagaagtc gaagaaaaaa cgattatctt gccttatgga atcgaagaaa
     2341 aaggatctac aaaataataa aaggacaacc attcagaggt tgtgagcctg ccgtttaact
     2401 ctgcgttaca aggagcaatt tcaaaaaaca gcatttcatg tttgatgaat attgtgactc
     2461 gtgattcgga gttggcagga gaacaccgtt tattcgggaa aaggggttat gacaaaattt
     2521 tgttataatc ctttttttgt gtcttaaaaa agagagaaag tggttgaaat tacatttatc
     2581 gtatataaaa caatccgtgt atagatgctg cattttgttc accaccatca aaaaaataag
     2641 ggactgtgac aatactattg tcacaatctc ttattactgt gtattctatt aaatcaatca
     2701 tctttctcat ctgattcttt ggttgcttga ttcgctcttg cataagctga agcggtgttc
     2761 cagtaatctg tatagttttc atcggtaccg ccaacgccaa atttaaaggc gcttttcttc
     2821 ggtccatttt tcgcccatag cgattcaact gtttttccag gtgtttggat ggatttttta
     2881 ttgacagtaa cttttccagg tgtttgacca gtaaatccag atactttttt cttcatcaca
     2941 tcagatgata attcgaattt ctcatcagtg ccaaaaatgt caggttttgc ttggtaagct
     3001 tgattgatca gattggcaag ataattagcc gaacgtatcc ttgctttgct gtccattcca
     3061 gtattgtcat cgtgccctgc ccagctactg atggtaatag acggagtaga gacaattagc
     3121 catgaatctc ggtattcatt ggtagaacca gtttttccga cccaatctgc ttttcctaga
     3181 tttccgttta agcttgagat ggcatctttg aatggtgtag tgatttttgc attgatcaca
     3241 ctgcgcatca tgtcattcat gatcgatgcc gttgcttccg aatagatccg gacagagttg
     3301 ctttcgtgtt tataaattac atttcctgcg ttatctgtga tggaatcgat gatatagcct
     3361 tcttcataga cgccgccgtt tgctaaagcc tgaaatccat tggtctgttg aagcgtcgtg
     3421 acatctactg tacctaaagg agcagattca acgccccaat tgtcatttgc cgggtagttc
     3481 atctttgcca agtagtgctc gtaagcatat tgtttcgatc caccggaatt caacacatct
     3541 tgatataagt gataagccgg gatattgttg gaccattcta gtgactcacg gacggtttgg
     3601 aaggtgttcg atccttcgtt agtagcattg acgattttct cgccagcatt ttctccttct
     3661 tgccaagttg ttgcataatc tgatacacgg gattctgatc cgataagccc catgtcgatt
     3721 gcaggtccat aaacaagaac tggtttgatt gatgagccag cttgacgttc tgtatcgaag
     3781 gcatggttat tttgattctg actgtaattc cgtccgccaa cgaatccgta gatgcggcca
     3841 gttctgttat ccatcaatac atttccggtt tctacttgac tgccagcacc atcatctaac
     3901 atgtatccat aattttctac gccattttgc aatgcagcat agacatcttt atcgattgtc
     3961 gaatggattg tatatccttt attttggatt gtttgctgtg ccttttgata ataagcgtca
     4021 ctgaccgatg aatcagacat atcagcgttg tctttttcag ccaattgttg tgcaatgatt
     4081 cttgttgctt cattcatcac agtataatac aagaattctc tgtcagtctg ttctgcgatt
     4141 tgttgtggta gaaagtcttt tgtaaggtca taggcttttg cttcttcgta ttgttctttc
     4201 gtaatttggc cttcacgata catactgaat aaaacaaaat cttttctggc aaggccggca
     4261 gaaagatctt cttttagcgc acctgtgttc gtgtatggac tatacgtgat cgggctttgg
     4321 ggtaatccag cgatataagc agcttgcggc agcgtcacat cttttgcatc tacaccaaag
     4381 attcctcttg cagcttcctg gactccagca atgttttgtc ccttattatt acgaccaaat
     4441 ggtgagacat tcaaatacgt agcaatgatc tcatcttttg aaaagtattt ttctacttgt
     4501 gcagaaagaa tgatctcgtt tgctttacgt ttgaatgttg tttcatctgt aaggatctgc
     4561 tgtttgacta attgctgtgt caaagttgat ccaccagaag agccaatacc agtagcttca
     4621 gatactaacg ctcgtaaaac agctttagga acgtaacctt ggtgtttatc gaagtattca
     4681 tcctctgtgc tgataattgc agttttcaat aaaggtgaaa ttttatcaga tgaaatagtc
     4741 gtgcgcatca gatctgtctg gatttttgat atctctgtat tatctgcata aacaatcttt
     4801 gacgtttctg taatgtttcc tagttctgtc tgcagtgctt ttttagtcgg caattgtgtg
     4861 tcttcgacga gataggcaaa atagccagcg cctattccaa tacctagagc tgcgaacatc
     4921 aaaagaagaa cagtaataaa aacagtcaat gattgaaaaa ctctaaaaat aatcttagga
     4981 acaaaccatt tttctttttt tcttctattc tgtttttttc gagtattttt gcgtggcaaa
     5041 agggtcacct caactaatgg ttttatttcg ctaattatag caaataatag aacaaaaaaa
     5101 cagacaaggc tgtttttggc aggaatttct tttttaaagg agttaaaacg tgagaaaatg
     5161 atctttttta taaaagagtt cttaagcttt tctttagaga aaatttcagt tactatggag
     5221 aacagggcaa agaaaaatca atcattttct ttgtatatca tcttaccaat atataggaat
     5281 tgttagtaac aattgccttt caaggaggaa tccatccatg ttattaggct cacacgtcag
     5341 catgagcgga aagaaaatgc tgttaggagc agcagaagaa gcagccagtt atggatcttc
     5401 gacttttatg atctatacag gcgcccctca aaacactaga agaaaagcca tcgaagagat
     5461 gaatattgat gccggaaaag cgtacatggc agaaaacggt ctaacaaata tcgtcgttca
     5521 tgccccttat atcattaatt tggggaatac gatcaaacca gaaatgtttc cttttgccgt
     5581 ccaatttctg agagaagaga ttgttcgtgc ggaagcttta ggcgctactc aaattacact
     5641 tcacccaggt gctcatgtag gggcaggaac agaagccgga attgctagaa ttattgaagg
     5701 cttgaatgaa gttttgacaa aagaacagac ggcacaaatc gctttggaga caatggcagg
     5761 taaaggtacg gaaatcggtc gaacatttga ggaattagcg caaatcatcg atggagtaaa
     5821 attgaatgaa aaattatccg ttacttttga cacctgtcat acgaatgatg ccggttataa
     5881 tattaaagaa gacttttcag gtgtaatgga agagtttgat aagatcatcg ggttagatcg
     5941 gcttaaagta ctccatatca atgattctaa aaatccgcaa ggttcgcata aagaccgaca
     6001 cgccaatatt ggttttggaa caatcggatt cgacacgctg aataagatcg tccatgatcc
     6061 aatgtttgac aatatttcga aaatcttgga aactccctat gtcggcaaag ataaaaagaa
     6121 agcttacgca ccatatggaa aagaaatcgc catgttcaaa gcacaaatat tcgatccaga
     6181 agtgtttcct gagttattag cagaagaagt gatactctaa gattttctat ctgacagcag
     6241 caaaaaagga ccaggcacat tgccttgtcc ttttttgttt aagaaacaaa ggagtgcttt
     6301 ttgcagtctt tttcatcatg catcttctcc cccctctttt taaatttaga caaacagggt
     6361 atactggtag aaaagtaaaa aaacgaaaag tttcacaagc aagtggcaaa acgtgattgg
     6421 aaggacgaaa agatgctgaa cactttaaaa cccttgatca accaactaaa aaagaaacat
     6481 acatacttta ttcttggcat agccctatta tttacaatta ttcgtttgta tttatatagt
     6541 aaagcaatct atggaacaga catgtcggca acctatgatg accagctgct gattcgctat
     6601 gctcaaaata ttttggacgg taaatggcta ggggagtata cgactacaac actttccaaa
     6661 ggaatctcct acagcttatt tttagtactt gcacataaac tgcatctttc ttatgcagtt
     6721 ttgttcggca tgttcagtat ttttgccagt atattggttg cactcgcgtt taaaccgatc
     6781 gtgaagaaca agtatcttct tttaagtttc tatttttatt ttttgttttc tccgattagt
     6841 tttacacatg aatattccac tcgaacgtat cgtaatgccc tcgtgattcc ggctgttgag
     6901 atcattatcg cttgtttact agctatttat taccgcaaat acggttctag cagaaaattg
     6961 ctgccatggt ttttagggct ttctgtcgct tttcctttct tttggttcat tcgcgaagat
     7021 tctatctggc ttcttccttt tactgtagta gctttgggta tcagtttcgt ccagatcttg
     7081 ctagggcaag acttttcttt caaagaagta aagaagttaa aaaaacgact ctttcttctc
     7141 tcgaaacggg aatggctgaa actttcattg tttttacttc ctatagttgg cttttccatc
     7201 gtctatcagt ggatcgaata taaaaatgag acaacatacg gtattgcaac catcaatgac
     7261 cgttccagtg gagaatttgg acgtttgatg aaacaactga tccgaataga tgatgaaacg
     7321 aacttgaata aagaaaacag tgagatatgg gtctcacatg ctgcactaaa taaagcatta
     7381 gccgcatctc ctacattcca tactgtttct acccgtattg acgaattata tacgactcac
     7441 gcgtggactc aaggtggaaa agtaaaagaa ttacccggag atatcatctt ttgggcattg
     7501 cgagatgtgg taagcgaatc tggttattac caaaacaatg caaaagaaac caatgatttt
     7561 tggaaaaaag tcaaccaaga attagaagaa gcctatcaca agggaaccat caaaaagaaa
     7621 aaagagttct atctgatggg atcaggagat ggaaagacga tgagtgatct accaatcgta
     7681 ttcgatttcc ttcaatcagg atacgcttat gcatggcgat ataaagattt ccatcaagga
     7741 ggaaattata gtttcggaac gcaagaacaa gtcaaacagg ctcaagaatt attaaacctt
     7801 ccgctaatgg agaattggat cgatagtaat gaaccgagaa cacctaattt ccaattaaca
     7861 aaatcagcaa aagtcgcgaa tgtcatcata aaaatttacc aagttctggc tattcccgtg
     7921 ctgattgctt caatagcagg gatattactt atgatactag gaaccgtatt tgcaaaagct
     7981 gatcgtgcct attatagttc ctctttgatt gtggtcaccg gattaatact gacacaattg
     8041 gtttttcttt tcggtgtctc gtggttttgt tcttatgcgc cagaaaaaaa ggattatttt
     8101 ttaagtgtct acactggcgc aggcgtgccg ttaacgcaat tcatcgtagt aacaagcatg
     8161 ctagttttca gtaaattaaa tctgaaaaaa gctttatctt ctaaataaaa agacccttgg
     8221 tagctagatt tttaacctaa ctatcaaggg tctttgtgtg gaaaaatcag tttttattcg
     8281 atttcttcta ccatttcctg caaacgctgt tcatattttt tgtttccttt atataaatca
     8341 ccaatcgtcc atgccaacag gaggaggaca agaacaatga ttacataagc gatgtgatca
     8401 gccaatgcta gttgagcgga agtggcttgc tcgccgaaga aactttcgat ctgtcctggt
     8461 aatcctcgta agttcaagta agttagacta atcacagaga accagccaag aagttttacg
     8521 atgaatgaat ttttaaatcg gctacccatc tccgcttggc tgttggtcat catcagtaaa
     8581 gggatcatcg aaaacggcaa cgcaaaagcc aagaacacct gggattcatt cattaagtta
     8641 ttcaaagcgg tatgttcttc gatcgttcct tttgtacttg taaacaaaac acaaatcaat
     8701 acaggaatca cagaaagcaa tcgtgtgacc agtcttctta gccaaatcgg gatacgcata
     8761 tggatgaatc cttccatgat gacttgaccg gtcaacgtac cagtaatagt agagttctgg
     8821 ccagaagcaa gaagtgctac agcaaataaa gtggacaaga taccagattt tgctacagca
     8881 atcaagatac cattgctcat agctgatgga tcagataaag cttcatacag accaaaaaag
     8941 gaaggatctt gaacagaacc ggttttgaag acagcgacac ccataatcaa tagcagcgca
     9001 ttgactagaa aagccatcga caattggata ttagagtccc aagtagaaaa acgtacagct
     9061 tgtgctacat cttcttcgtc ttggtgatcg atcttccgag tttgtgaaac tgctgaatgt
     9121 agatataagt tatgtggcat gactgttgcg ccaataatcc ctaatgctcc agttagcgga
     9181 gtttcgccac caatgacagg tgagtcggag aatgtatggc tgttagggat aaagccagca
     9241 aataaactgt gccaatctgg gttagacaag ccaacttgat agacaaaaac gaataaaatg
     9301 acgaaaatca agcagacaac cagtgcttcg atcttacgaa acccgacttt tgtcagtagt
     9361 aagagaacga aaacatctaa tacagtaata aagacggcaa tcaccaatgg aatatcaaaa
     9421 agtaagtaga gggcgattgc tgcaccaatg acttctgcaa tatctgttgc cataatggct
     9481 aattcagtca agatccataa aatgacaccc aatgtcttac ttgtgcgtgc tcggattgct
     9541 tgggccaaat ccatttgggt cacgattcct aattttgctg ccatatactg taaaagcata
     9601 gcaatcagac tagacatcaa aataactgac atcaataaat attggaaatt ttgtcctccg
     9661 gtgatcgaag tagaccagtt acccgggtcc atatacccaa ctgctactaa cgcaccaggt
     9721 ccagagtaag caagaagtgt tttaaaaaaa cttttcccct ttggtacatc cactgttcca
     9781 tttacttcag ctaaagataa accatttgta tgttcaataa gtcgatgctt atgaaattgt
     9841 ttgttggatt gattattcaa gaaaaaacca cctttcctat ttatctacga ttacattcta
     9901 cacctcaaaa agaaaaaatt aaagaaaaag attcggtatg cctaattttt tttcgtggcg
     9961 tgtcttgcta gatgacgaaa gaaattttgt tctcctctaa aaaaaccact attttttgca
    10021 tgaaactaaa gaatacgcct ttcttttttc aataaacttt agtaaaataa gtcattgaga
    10081 gcaattcgga aatagaaagg agagatttat atgttatcaa caggtattgt cgtacttatt
    10141 gctattattg ctttgctaat cggcgcagta ggtggctttt tcctagcgcg taaatatatg
    10201 aaagactatt tagaaaaaaa tcctcccgtt aatgaggaca tgttgcgatc aatgatgatg
    10261 tcaatggggc aaaaaccatc tgagaagaaa attcgccaga tgatgcagca aatgaagaac
    10321 caagggaaaa aataggttct gacccaacga ctttttacgg gctgattttt tcagtccgtt
    10381 ttttatttcg taatttgtta gactattcag attattcagc aaaaagacaa gcacagacaa
    10441 tcctaggctc ttgataaaga caaaggagga gtaaaatgtc gatttttaga aagttaggct
    10501 ggttttttcg tcaggaaaag aaacattatt taattggggt tttctcgcta ttcgcagtgg
    10561 ccttggtaca gttagttcct ccaaaagtga ttgggatcat cattgatgag attgccgata
    10621 aaaatttatc agtaaagatc attttcgggt ggatcttcct attgattatc gctgcttttt
    10681 tacaatatct ttttcgttat atctggcgga cgaatatttg gggaagtgca gctcggttgg
    10741 agaaagaact tcggcagcag ttattcaaac attttacaga aatggacaat ctcttttacc
    10801 aaaaatatcg gactggggat ttgatggctc atgcaacgaa tgatttgaat gcgatccaga
    10861 atgtagcagg agctggtatc ttgacctttg cagattcagt gattacgggc ggaacaacga
    10921 tcattgcgat gattttgttt attgattggc gcttaacact gattgcgctg attcctctgc
    10981 ctttgctggc cgtcacttca cgagtgctgg ggtcgaaact ccatgatgct tttcgtgatt
    11041 cgcaagaagc tttttctagt atcaatgata agacacaaga aagtatcact gggatcaaag
    11101 tcattaaaac atttggacaa gaaaaagaag atctagcgga ttttgaagaa aagattgaag
    11161 atgcaattat taaaaacaaa cgagtcaatt ttttagactc cttatttgat ccattcatta
    11221 ccttgattat cggtctgtct tatgttgcaa caattatttt aggtggaaag tatgtcttgg
    11281 aaggcacgat ctcgatcggg cagatggtct catttattag ttatatcggt atgcttgttt
    11341 ggccgatgtt tgcgattggt cgattgttca acgtattgga aagaggaaat gcttcttatg
    11401 atcgcgtcaa tgaacttttg catgaaaaaa cgcatatcgt ggaacaactg ggtgcagtgc
    11461 agaccccggc aaaaggcgag ctgaatgtag ctatttcctc ttttaattat ccgaaagaag
    11521 aatcaccagc attagaacaa atcaagtttg caatccaaga aggagaaaca ttaggtattg
    11581 ttgggaaaac tggtgcggga aaaacgacga tcatcaaatt actgatgcgt gaatacgatg
    11641 attatcaagg gaaaatccaa tttggcggac gttcgatcaa agaatattca ttgaatgctt
    11701 tattaggatc aatcggctat gtgcctcagg atcacttctt gttttcgatg accattcgag
    11761 ataatatccg tttttctaat ccaaaacttt cagaagaaga agtagagcat gcggcttctt
    11821 tagcatttat caacaatgaa atcaaggaat taccaaaagg ttatgatacc ttagttggag
    11881 aacgtggagt ctctttatct ggcggacaga aacaaaggat ttcgattgct cgagcattga
    11941 tcaaaaatcc tgaattatta atattagatg atgcactttc tgcagtagat gccaaaacag
    12001 aagaagctat cttgcataat ttaaaagaaa taagaaaaga gaaaacaact atcatttcag
    12061 ctcaccgttt aagtagcgtg atgcatgcaa aagaaatcat tgttgtcgat caagggaaaa
    12121 tcattgaacg aggaacccat catgagctgc ttgcactagg cggctggtat gaacaaatgt
    12181 gggagaaaca gcaattagaa gcgaagatag aaggaggcga ggcctgatgg atgaaaatta
    12241 tcaatcggaa tggacaaaat cgattccact taaagaacag aaaaagatca tcaaacgact
    12301 gatgaagttc gccaaacctt ttagaagaac gttcatcgtt gctatcttat ttgcgtttgc
    12361 tctgtctgtg atcaatgtcc tattgccaag gatcatccaa acttttatgg atgatcatct
    12421 ggctaaacag tcggctacga cacaagttat tttgtttttt gctggtatgt acttatttgg
    12481 agtcatagta aaaagtatca tttggttttt ccaatggtat ttgtattcca tggcttcatt
    12541 gaagacctat cagtatatta gggtaaaatt atttgaaaag ctgcatacac taggtatgcg
    12601 ttattttgat cagacaccgg caggatcaac cgtttctcga gtgacgaatg acacagaaac
    12661 gctatttgaa ttttggtacg tctttttgat ggtattgact gggatctttg cagtcgtttc
    12721 ttcattcatt gccatgtttc aaatcaatgg agaaattgcc ttgtggactt tggtgttctt
    12781 gccaatttta ggaatagtca tctggtatta ccagaaattt agttctcgta tttaccggaa
    12841 tatgcgggaa aaattaagtc agctgaatac gaaattgaat gaatcgattt ccggcatgcg
    12901 tattatccag cagtttcgcc aagaagctcg tttagctaaa gaatttgaac aagtgaacaa
    12961 tgagtattta gacacgcgtt atgcgatgat caaaacaaat tcgattctgt taagtccgat
    13021 catcaatttt ctatatgcat tggcgattgc gttggtgttg actttgtttg ggatcgatgc
    13081 gttgcattct cccgtagaag ttggactgat ctatgcattt acgacctatg tccagggatt
    13141 ttttaatcca atgtctcaaa tgatggactt tttgagcatc ttcacagatg ggatggttgc
    13201 tggtagtcgt atcttgaaga ttatggatac agaagaatat gcaccacaac aaaaccctgg
    13261 agcagatcaa atgattactt caggtaagat tgagtttcgc aatgtaagct tttcttatga
    13321 tggagagcac aatgtattaa acaatatctc ttttgttgct aatccgggag agaccgttgc
    13381 attagtggga cacaccggaa gtgggaaaag ctcgatcatc aatgtgttga tgcggtttta
    13441 cgaattttat gaaggtcaga tattgattga tgatcatgac attcgagaat atccaatgga
    13501 agagttacgt aagaaaatgg ggctggtctt gcaagatgct ttcttgtttt atggggatat
    13561 cgcaggaaat attcggatga tgaatccagc tatcacagac gaacagatac gccatgcggc
    13621 tgagtttgtt caagcaaaca aattcatcga tgaattacca aaaggatatc actcaaaagt
    13681 gatcgaacat ggtgccagct attctagtgg acaacgacag ctgatcactt ttgcgcgaac
    13741 aatcgtgact gatcctaaaa ttctagtatt ggatgaagca acagcaaata tcgatactga
    13801 aacagaagga ttgatccaag aaggattggc gaaaatgcga caaggacgga caacgattgc
    13861 gattgcccat cggctgtcaa cgattcgaga tgcagaattg attttagttt tagacaaagg
    13921 tcatatagta gaacgcggga atcatgaaac acttctagcg caaaatggtt tgtatgcaga
    13981 tatgtacaaa ctgcaaagca gtggtatata aaagatgttg tgacagtagc attttgacct
    14041 aagcactaga gtgaaaataa aacatagctt cccatatttt tcatctgtga gagttagtgt
    14101 cgtagttacc agatttaaaa aagacgacgt cagctagtca gaagtgccta atagccccta
    14161 agaaagcgtt gacaaaatcg tttgctttcg ataatataaa gaaaacgata caacttggat
    14221 agtgattgcc tgatgcaagc taaacctaat gagtctccca tggtttcatg gacggctttt
    14281 tgggtttttc tttttgtttt ggatacagcc ctatatatca tggaaaggag caaaacatgc
    14341 tgattgagaa agtactgaat aacaacgtcg taataacaag ggatgaaaga gatcgggaaa
    14401 tgattgtgat gggaaaagga ttggcattca aaaagaaggt gggtgacccg attcttgatt
    14461 catgcatcga caaaaaattt cagttgacaa atgacggact ttcacaacag ttccaagaat
    14521 tggcacaagc gattcctctt gagtacttag aaatttcttg tgaaatcatt gaatatacaa
    14581 aagaggctct gcaagtccat ttaaatgatt ctgtgtatat ttcattgacg gatcacttgt
    14641 atacagctat cgaacgtcaa aaaatgggga tctttgtgcc aaatgtattg ctgtatgata
    14701 tcaaacaact gtttcctaaa gagtatgcca ttgggaaaaa aacagtgaag aaaatctcgg
    14761 ataaatacca catcaagtta tcagaagacg aagccggatt tatcgcattg catttagtca
    14821 atgcacaagg cattcaaagc cagcaagaca atacctacct gtttaccaca acaatacagg
    14881 atattttaaa tatcgtccgc tattactata agattacatt tgatgaagat tcagtccact
    14941 tttttcgatt cgtcacacac ctgcgttttt ttctgacacg tgttctagat ggagcgaaat
    15001 cagaagatgg agaagtttct gaggaattgt tccaagttgt tcaaaaaaaa tataaggata
    15061 cgtttggttg cgttgagaaa atagcagact ttttaaccgg ggctttcgac taccagatgt
    15121 ccacggatga aaaaatgtat ttaacgatcc atactgcgcg tttagtgcat gagaatcgtt
    15181 gtaaataaat aaaaaaggag gacaaattaa caagaacgta tgaaaataag ggtagtgaca
    15241 ttcagttggc taaaccttcc actaattaat tggagggaat agaaatggga aaataccagg
    15301 aattagcaga aaacatcgta aagaatatcg gaggaaaaga aaatatccgt agcttgacac
    15361 actgtgtgac gcgacttcgt ttcaaactaa aggaggaaaa taaagcaaag gatgatgttt
    15421 tgaaaaagat ggaagggata gtcaccatca tgaaaagcgg cgggcaatat caagttgtaa
    15481 tcgggaatca tgtgccagat gtctatgcag aagtactgac agtagccggg atttccgatg
    15541 aagtagaaga agaggtttct tcaagtagta atctgttcaa tcgattaatc gacatattaa
    15601 gtggctgttt ccagcctttt ttaggtgctt tagctgcagc gggaatggtc aaaggattaa
    15661 atgctttgtt cttgtttctc aaattttata ctgaaggatc gggtacgtac atcatgctga
    15721 atgggatagg ggatgcaatt ttttatttca tgccagtgat cttagggtac acagcagcga
    15781 aaaaatttca tctgaatccg atggtggggc tcgtgattgg tgcagcactt tgttatccga
    15841 ctgtacaagg agcagcacta caaagtggtt tccctgatgg cagtcctgcg ccttatagct
    15901 tgctgggtct tccggcttat gaaacatttt tgggtatccc atgggtgggc agcagttata
    15961 ccagtagcgt cgtacctgtt atcttcatta tcgcatttgc cggacaagtc caaaaaattg
    16021 ccaagaaatg gattcctgca gtcgtccaga cctttttggt tcctttttct gtgttattaa
    16081 tcgcacttcc tgctggcttt ttgattatcg gtccgattgt cagtatactg acagatctat
    16141 taagcacggg attccaagca ttgatggact tttctccagc tgtgtatggt gcagttctag
    16201 ggtttctttg gcaagtactg gtgattttcg gacttcattg gagtattatc cctcttgcga
    16261 ttatgcagct agcgcaaaat gggtggagtc agatgttagt aggcgtttat ggcgcgagtt
    16321 ttgcacagac agcagtggta ttggcgatgt atttcaagtt caaggatcaa aaaatgaagg
    16381 cgctttgcat gccagctgtg atttcaggaa tcttcggcgt aacagaaccg gctatttatg
    16441 gaatcacctt accgaagaag aagccattta tttactcgat gattggtggt gccatttcag
    16501 gaatctattt gatggcatct ggaacaatca gctacacaat gggcggatta gggatttttg
    16561 gggtggtaaa ctacatcacg gaaacagacg ccagtggtat gtttcaagcg tttatcggca
    16621 ttgctattgc ttcggtaatc gggttttcgc tgactttttt cttttggaag gatgaagcag
    16681 gtgaaacaga tgctatacag aaaaaatcag gtaaagaaat tgtaaaaaca ccgatacaag
    16741 gacaaatcgc tccactaaat gcagcgaagg atgcagcttt tgcacaagga acactaggtc
    16801 gaggaatctt gatctaccct gaaaaaggag aagtacgtgc cccttttgac ggaacagtca
    16861 tgaccctgtt cccgacgaaa catgcaattg gaatggtttc tgaaacaggg ctggaattgc
    16921 tgattcatgt cggattggat actgtgcagt tggaagggaa atattttgaa agcttagtgc
    16981 agcaaggaga aagagtgaaa caaggcgatc tgttgctacg cttcgacaaa aagaaaatcg
    17041 aaaaggaagg atacagttta gaaacacctg tgatcgtcac caattacacg gattatttgg
    17101 atattttgga aaaccaaggg gagacggtcg ggccagacga tgcacttatc accgcactga
    17161 cctgaacggt taggtgaaga atggaatagg cttaactatt ctttttattc cacttcttta
    17221 ttttcaaaat tgaaaggctc tttcatgatg gctgagctga tagggcgttt atcgaatttt
    17281 tgaccgacag aaattagatg gactaaattc tgttgataat tttctgcaaa aacacaacta
    17341 tataacacgt ctagaagata acaaattgat gtattgatcg taaaattacc aatttttgaa
    17401 tacagtcgct cgcgtgtcgt aagtcgcaaa gcggctgtac tcattgcaga tagcgttgaa
    17461 tcaccgatac tggtcaaagc taaaattgga acatgatttt gtttcaatat ttctgcggta
    17521 cgaagaatca ctttattttc acccgtataa gaaatcagga tcccgcacat atcgctcgtg
    17581 caattgtacg cttcatagaa tgattcacca aaagtggtga caattgtgac atccattttg
    17641 atgcgcttca ttttcagcat gaaatcttga gaaatcaaag tattcgagtt actggcgaag
    17701 atcacgattt tttttgcctg gagcagtaaa tacttggctt tttgcagttg gtcatgatga
    17761 atgagagaaa gtgtatcttg aatcgtcatc tgttctaaag aagccatttt atttgcgatc
    17821 gtcataatac cgtctgtggt ggaaaaagga agattcgcat ctacgtcttg aaaattccct
    17881 tcaagatagg ctgtttcagc taaaaaagca ttacgaaaac tgacccagcc atcaaaaccc
    17941 attttttttg ctacacggat gagtgtagac gggtggacat agcatcgctc agcgatctct
    18001 tggatggtca tttcgccaag tgctggagaa tcgcttaaga gaaactggat cacttcattt
    18061 tctgaaggag aaaaggagat ttctttgatt ttttcacgta ataacatgta gttaccttct
    18121 tcttattttt ttacgtaaat tataactttt ttgaaaatgt tttgtaaacg gatttatact
    18181 atataactta aaatagactt tttttgacaa gatatttaca aaaatccact agaaaacagt
    18241 aacttttgta aatgttactg gaaagaaacg gatttctatt gtttgttttg tttacaaaaa
    18301 agataatgaa agtgtaaaaa agtaaaggag tgagaacatg gcaaaaggaa tcaaaatcgc
    18361 tacgattggt ggaggcagca gttacacccc tgagttgatg gaaggattta tcaaaagata
    18421 tgaggaatta ccgatacgag aaatctggct cgtagatgta gaagaaggaa aagaaaagct
    18481 tgagatcgtt agtcagatgt ctcagcgtat gtgggatgct tctccgtatg aagtcaaaat
    18541 ctatgcaact ctggatcggg aagaagcatt gaatgatgcg gattttgtta cgactcagtt
    18601 tcgtgtcggt caattagatg cacgaatcaa agacgagcgg atccctagtt attatgggat
    18661 gattgggcaa gaaacaaatg gtgctggcgg gatattcaaa gcttttcgta ccgttccagt
    18721 ggtcttggca atcgttgaag acatgaagcg tttatgtcca aatgcttggc tgatcaattt
    18781 cgcgaaccca agtgggatgg tgacagaagc agttatcaga tatggcaaat gggataaagt
    18841 gattggatta tgcaatgtgc cagtaatggc gatgatgaca gaaccagcaa tgcttggcaa
    18901 gaaaaaagaa gagctgatct acaagtttgc cggtctaaat catttccatt ggcacaaagt
    18961 agcagataat aaaggaaatg accgcacggc agaattgatt gatcgtttat acgatgaaga
    19021 caatggattg ccgaaaaata tctttgatat cccgtttttc aaagaacaat taaaacaaat
    19081 gaatatgatc ccttgtggct accaccgcta ttactaccgt gaagaagaaa tgctggaaca
    19141 tgctttagaa gaatatcaaa cgattggtac aagagcgcag caagtgaaag aaacagaagc
    19201 agagctattt gaattataca aagatccaga attagaccat aaacctgaac aattgcaaaa
    19261 acgaggtggc gcttattatt cagacgctgc ctgtgaaacg attgcttcaa tctatggaaa
    19321 taaagaaaca cagatcgtgg tatctacaaa gaatgatgga gctgttcctg acctgccggc
    19381 agattgtgta gtagaagtca ctgcctatgt tggcgcacaa ggagcgagaa atgtagcgtt
    19441 tggttctctt cctgctgctg aaagaggctg gttgcaagta atgaagaata tggaattgct
    19501 gacgatcgaa gcagctgtga ctggtgatta tgggacagct ttacaggcgt ttacgatcaa
    19561 tccgcttata cgatcaggaa agacagcaaa acggatcatg gatgagttgt ttattgcaca
    19621 ccagcagtat ttaccgcaat tcaaggaaac aatcagccga ttaaaagaag aaggaatcga
    19681 agttcaagat gaactggcaa gagaattatc aggtaataca catataatgg aggaagtata
    19741 atgggattca gaaaagattt tttatggggc ggtgctacag cagccaatca atgtgagggc
    19801 ggttatgatg aaggtggacg cggactagca aacgtagatg ttgtgccaat cggaaaagac
    19861 cgttttcctg ttatcaccgg aaagaaaaaa atgtttgaat ttgatgagga tcatttttat
    19921 ccagcaaaaa ttgcaatcga tatgtatcat cgttataaag aagatattgc tttgtttgca
    19981 gaaatggggt tcaagactta tcgaatgtcc atcgcctgga gtcgtatttt tccaatgggg
    20041 gatgaaaaag agccgaatga agctggcttg aaattttatg aggatgtctt taaagaatgc
    20101 caaaagcacg gaatcgagcc acttgtgacg attacgcatt ttgattgtcc aatgcatttg
    20161 atcaaagaat acggtgcgtg gcgttccaga gaactcgttg gtttttatga aaatctgtgt
    20221 cgagtcatct tcaatcgata taaaggactt gtcaaatact ggctgacatt caatgagatc
    20281 aatatgatcc ttcatgcacc attcatggga gcaggactgt actttgaaga aggagaaaac
    20341 gaagaacaag tcaaatatca agcggcacat catgagttgg ttgcaagtgc catcgcaacg
    20401 aagattgctc atgaagtaga tccggagaac aaagtaggct gtatgctggc agcaggagca
    20461 tattatccat acacttgcaa tcctgaagat gtttgggctt ctagaaaatc agatcgagaa
    20521 aattatttct tcattgatgt tcagtcacga ggagaatacc cagcttatgc attgaaagaa
    20581 atggaacgaa atggcattca gatcgaaatg gaaccagggg atgccgcatt gctgaaagaa
    20641 catactgttg attttatctc tttttcttat tattcttccc gagtttcgac taccgacaac
    20701 gaactcttgg aacagactgc aggaaatatc tttgcttctg tcaaaaatcc atatctgcaa
    20761 gcaagtgaat gggggtggca aattgatcca ttaggcttga gaataacgat gaatgatatt
    20821 tatgatcgtt atcaaaaacc attatttatt gtagaaaacg gcttaggtgc agtcgatacg
    20881 ccagatgaga atggttatgt ggaagatgat taccgaatcg attacctggc agcgcatatc
    20941 caggcgatga aggatgcagt agaactagac ggagtcgatc tattaggcta tacgacttgg
    21001 ggatgtattg atttagtatc agctggtacc ggtgagatga agaaaagata cggattcatt
    21061 tatgtcgatc gtgataacca aggaaatggc acattagccc gttcaaagaa aaaatcattc
    21121 aactggtata aaaaagtaat tgattcaaat ggagaaaatc tttcgaacga ttgatcaatg
    21181 atttataaaa gtctattgtt tttcagcgga tttttcgagt ataataaagc tattcgagaa
    21241 acgcaagcag aacaatagac tttttttcgc attggctgta aagtatgctt acttgattaa
    21301 gtaaaggaga atctacatat gtatgatgta atcgttattg gcgcaggtcc tgctgggatg
    21361 actgctgctt tatatgcttc acgttcaaac ttatccgtat tgatgatcga acaaggtgcc
    21421 cctggcggcc aaatgaacaa tacggcagaa atcgaaaatt atcctggatt cgattcgatc
    21481 atgggccccg atctagctta taagatgtat gaaagtgtct caagatttgg gacagaaaat
    21541 gcttatggaa tcgttcaaga tatcaaggat cacggcagcc ataaagaagt catctgtgaa
    21601 gataaaagtt acgaaggaaa aacagtcatt atcgcaacag gctgtatcca ccgtaaatta
    21661 ggcgtacctg gcgaggaaga atttgctgga cgaggcgttt cttactgtgc agtctgtgat
    21721 ggtgcgtttt tccgtaacaa acgtctagta gtcatcgggg gtggggactc agcagtagaa
    21781 gaagccatct atttgacaca atttgcttct gaagtagtga tcgtccaccg tagagatgaa
    21841 ttacgtgcac aaaagatcat ccaagaccgt gcatttgcaa atgaaaaaat ttcctttatg
    21901 tgggatacag tcgttgacga aatcgttgga aacgaaatgg tagtgacagg tgtgaaagca
    21961 cgtaatgtca aaaccggcaa tgaatttgat ttagcagcag acggagtatt catctatgtt
    22021 ggactggatc cattaactgc accttttaga gaagcaggtt tgacgaacga agctggctgg
    22081 attccaacag acaacgaaat gaaaacgaat atgccaggcg tttttgccat cggagatgtt
    22141 cgtgaaaaag atttgcgaca aatcactaca gctgttggtg acggcggtat tgctggacaa
    22201 caagtgtata aatacttgga atctttagaa gaaacaactg cataagttta aaaagagtag
    22261 aagaacgggt tcaattgttc ttttactctt ttttttcgcg tgaaatttac tgaatctgat
    22321 ttatgcgaac acgtccaaca ccttttgata aaagaatcct ttcttgattt aagcgttttt
    22381 tggtcctcat actttcatat ctaataagtg aatgctatac ttattaagaa ccatatttca
    22441 gaaagaggtg ttattttcat gtcttgggaa caagtgtatg aacaatgggt acatgaagaa
    22501 aatttagaag aaaacttaaa aaaacaatta aatgatctgg gtgaagatcc tgaaaaactt
    22561 gaagatgctt tttatgcacc gttggaattc ggtactgcag gcatgcgggg aatcttagga
    22621 cctgggatca atcgaatgaa catctatacg gtaagacaag caacagaagg actagcacgt
    22681 ttcatggata cacaaggtga agaagcaaaa cgccgaggtg tcgctattgc ttatgactca
    22741 cgccatcagt caccagaatt tgcaatggaa gcagccaaaa cactggcaca tcacaatatc
    22801 ccgtcttatg tattcgaaag tctgcgtcca acaccagagc tttcttttgc agttcgtcat
    22861 ttgaagacgt ttgcgggaat catggtaact gcatctcaca acccagcggc ttacaatgga
    22921 tataaagtct acggagaaga tggcggacaa atgcctcctg cagacgcaga tgcattgacg
    22981 aaatatgtcc gtgaagtcag caatccgcta aaagtcgaag tattatctga cgaagaagct
    23041 aaacatagcg ggttgatcac gatcatcgga gaagaagtgg acgctgctta tctagaagaa
    23101 atcaaagcag tgacgattga tcgtgaattg gtagaaacaa tggggaaaga tttgaaactt
    23161 gtgtacacgc cacttcatgg aacagggaaa atgttgggcg aacgtgcgtt gaaacaagct
    23221 ggattcgaac aattcgtact agttcccgaa caagctgtgg cagatccaga tttcactacg
    23281 gtcaaatcgc caaatccaga agaacattca gcttttgaat atgctatacg acttggagaa
    23341 aaagaaggag ctgacttgct gattgcaaca gatcctgatg cagaccgttt aggcgcagcg
    23401 gttcgtttgc cagatggttc ttatgaagta ttgactggga accaaatcgg ggcattgttt
    23461 gctcaatata ttttggaagc acatcaatca agaggcactt taccagaaaa cgcagcggta
    23521 ttgaaatcaa tcgtttccag cgaattgcct acagcaattg cggaacacta cggtgctacc
    23581 atgttcaatg tgttgacagg gtttaaattc attgctgaaa aaatccaaca attcgaagaa
    23641 gaccattcac atacttttat gtttggattc gaagaaagtt atggttattt agttaaacct
    23701 tttgttcgcg ataaagacgc gatccaagca ttgcttttat tagcagaagt agcagcttac
    23761 tataaaaaac aaggcaaaac gttgtatgac ggcttgcaaa cgatttttga aacctatggc
    23821 tattttgcag aaaaaacgat ttctgtgaca atgagcggac aagaaggttc tgcgaaaatc
    23881 tctgctttga tggaaaaatt ccgtaaagaa gcaccgacag aatttgccgg agcaaaagtt
    23941 attcaaacag aagactttaa agaattgacg agaacagacc gtgaaggaaa cgtagaaaaa
    24001 ctaacaacac cgccatccga cgtattgaaa tatacattgg aagaaaatgg ctggattgct
    24061 atccgccctt caggaactga gccgaaaatc aagttttata ttggtgtaaa aggaagctct
    24121 acagaagacg cagccgaaaa agtagcctct tatgaagcga ttatcaaaaa gatgacagaa
    24181 gaataaaaaa cttgagactg atggaaaaag tggtaaactt tagaagtcag tcttttttca
    24241 agttggaggt gaatggattg ccagacacgc aaaaatcaaa agtagagaaa gtcagtcaat
    24301 tattcaaaat gttgagtgat cccactcgtc ttaaaattct gctatatctg aaagacgggg
    24361 aacaaaatgt gacagcaatc acccaagcag tggaaatgga gcagtctgct gtatcgcatc
    24421 aactacgttt attaagagaa aatcatgtcg tcaagtctca tcgcgaggga aaagcgattt
    24481 tgtatagtct tgatgattct catgtactgg atattttgaa ccagacactc aaacatgtgg
    24541 aacatcaata acgataggtg caaatagata aacactggag tgtgacaacg aaatttcttc
    24601 gttgtcacac tccagtgttt tttaagaaaa agacaaaaat gattaatcgc ttttttctgt
    24661 tgtttcagtt ccataataac tatgatcttc taggtctaaa gcattcaaaa taagcgaagc
    24721 cgtttcttca atagataaag atgccacatt gatcactaca catcctagtt tttcataaag
    24781 atcattcgca aaatcgagtt cagctctaat tttttcgata tcggaataag cagtatcagg
    24841 gtttaatccg taagagcgca tccgttcttt acggatatta tttaaaatat ctgggttatt
    24901 cgttagtccc acgatttttt taggatcgat ctcccaaagc tgtttgggaa tatgtgcttg
    24961 tgggatcaaa ggtaaattgg caacttttaa atttttgtta gctaaaaaca agctcaaagg
    25021 cgttttggaa gttcgggata cgcctagcaa aacgacatct gcttctaaaa aaccacgagg
    25081 atctttccca tcatcgtatt ttacagcaaa ttccattgct ttgatccgtt tgaaatagtt
    25141 ctcattcaat aaatggaggg caccaggttg ccgaattggc ttgataccgg ttaaacgttc
    25201 aatttctgat atcggtggcg tcatcacatc aaaactaaat aattgatgtt cttcacaaaa
    25261 agaacgtgtt atctcgatca gttcttgatt gattaatgta tgcaggacaa gtgctttttc
    25321 ttctaatgca tcttgcaatg cctgctttaa tgttttttca tctgtcacga acgttctgcg
    25381 gaataggttg aactcaacgg taggatactg agccatagta gcttgcgcta gttttgtcgc
    25441 agtttctcca gcagagtcgg agatgacaaa aaaagtaacg atttctgtag aatcggaaga
    25501 catggataaa acctcacttg catttttttt atgtttatta taccatactc tagaatgcgt
    25561 acttcgtaat cattttgatt tggaggaata agtcatgaaa aaacagacat tgatcgaaca
    25621 atcattagaa acattgaaaa ataacggttt taaatatact aaaaaaagag aagcattgtt
    25681 aacttattta gtgaagcgta accgctacgt atctgctaaa gaagtttttg actatatgaa
    25741 tcaggaattc aaaggggtaa gttatgatac gatttatcgg aatctccatg attttgcaga
    25801 gatcgattta ctggaagaaa ccgatttaaa tggagaaatg aagtttcgtt ttcattgctg
    25861 tcagggggaa atcggccatc accatcattt tatctgtaca gtgtgcggaa caacgaaaga
    25921 aatccatatg tgtccgatga attatttcga agaacagcta ggtggatgca cgatcgaagg
    25981 gcatagattc gagattttcg gaagatgtga aaattgtcaa taagggttta aataaaataa
    26041 catttgataa ttttaaaaaa aagcaagatt tccttgacgg tcaaaacagc attagatata
    26101 atatttacag gacagtcttg ttttttgaga tatatttcaa taacaattac ggttactttt
    26161 taagctcgga gggagggaat taacatgtca aaaacagtcg ttcgcaaaaa cgaatcactt
    26221 gacgatgctc ttcgtcgctt caaacgttcc gtgtcaaaag cgggtacttt acaagaatct
    26281 cgtaaacgtg aattctacga aaaaccaagt gtaagacgca agaaaaaatc tgaagcagct
    26341 agaaaacgca aaaaattcta gttctgtgat gaattggagt tggtagtgtg tcactactaa
    26401 gtagattaaa cgatgacatg aaagcagcga tgaaagcgaa agataaggaa tctttacaag
    26461 tcatccgaat gatcaagtca tctatacaaa acgagcagat taaagaaggt cacgacttga
    26521 cagaagaaga agaactaacg gtgttgtctc gcgaaatgaa acagcgacgt gattctttgc
    26581 atgagtttga agaagcagga cgtgacgatt tagctgaaaa agtaaaaagt gaaattgtaa
    26641 tagtcgaaaa atatatgccg gaacaacttt ccgatgaaga aattcgacaa cttgttcaag
    26701 aagcaatcac tcaaactggt gcttcatcaa tgaaagaatt tggcaaagtt atgggtgcaa
    26761 ttatgcctaa agtcaaagga aaagcagatg gaaaccaagt gaatgcgatt gtgaaagaac
    26821 tattacaatc ttaattttat catttaaact gcggacagtg attgtccgca gttttttgtg
    26881 ttcgtaaaaa aagaactaaa aa
//
LOCUS       DARPZJ010000034        26339 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.035, whole genome shotgun sequence.
ACCESSION   DARPZJ010000034 DARPZJ010000000
VERSION     DARPZJ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.035"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..326)
                     /locus_tag="SLE23_001735"
     CDS             complement(<1..326)
                     /locus_tag="SLE23_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8468639.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIP"
     gene            complement(1639..2304)
                     /locus_tag="SLE23_001736"
     CDS             complement(1639..2304)
                     /locus_tag="SLE23_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468640.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2484..4466
                     /locus_tag="SLE23_001737"
     CDS             2484..4466
                     /locus_tag="SLE23_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEI8468641.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4470..5108
                     /locus_tag="SLE23_001738"
     CDS             4470..5108
                     /locus_tag="SLE23_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468642.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            5136..5564
                     /locus_tag="SLE23_001739"
     CDS             5136..5564
                     /locus_tag="SLE23_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468643.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     EKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            6021..6932
                     /locus_tag="SLE23_001740"
     CDS             6021..6932
                     /locus_tag="SLE23_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEI8468644.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            7149..7586
                     /locus_tag="SLE23_001741"
     CDS             7149..7586
                     /locus_tag="SLE23_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468645.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7681..8565
                     /locus_tag="SLE23_001742"
     CDS             7681..8565
                     /locus_tag="SLE23_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEI8468646.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8789..11956
                     /locus_tag="SLE23_001743"
     CDS             8789..11956
                     /locus_tag="SLE23_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468647.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11976..12521
                     /locus_tag="SLE23_001744"
     CDS             11976..12521
                     /locus_tag="SLE23_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HEI8468648.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12549..13004
                     /locus_tag="SLE23_001745"
     CDS             12549..13004
                     /locus_tag="SLE23_001745"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HEI8468649.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            13001..13759
                     /locus_tag="SLE23_001746"
     CDS             13001..13759
                     /locus_tag="SLE23_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEI8468650.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13845..14585)
                     /locus_tag="SLE23_001747"
     CDS             complement(13845..14585)
                     /locus_tag="SLE23_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8468651.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14646..15899
                     /locus_tag="SLE23_001748"
     CDS             14646..15899
                     /locus_tag="SLE23_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEI8468652.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            16221..16448
                     /locus_tag="SLE23_001749"
     CDS             16221..16448
                     /locus_tag="SLE23_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEI8468653.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16571..16897
                     /locus_tag="SLE23_001750"
     CDS             16571..16897
                     /locus_tag="SLE23_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEI8468654.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16965..17678
                     /locus_tag="SLE23_001751"
     CDS             16965..17678
                     /locus_tag="SLE23_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEI8468655.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17988..18839
                     /locus_tag="SLE23_001752"
     CDS             17988..18839
                     /locus_tag="SLE23_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8468656.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            18960..20825
                     /locus_tag="SLE23_001753"
     CDS             18960..20825
                     /locus_tag="SLE23_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8468657.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20873..22282
                     /locus_tag="SLE23_001754"
     CDS             20873..22282
                     /locus_tag="SLE23_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEI8468658.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            22390..23091
                     /locus_tag="SLE23_001755"
     CDS             22390..23091
                     /locus_tag="SLE23_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8468659.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            23250..23729
                     /locus_tag="SLE23_001756"
                     /pseudo
     CDS             23250..23729
                     /locus_tag="SLE23_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            24577..25152
                     /locus_tag="SLE23_001757"
     CDS             24577..25152
                     /locus_tag="SLE23_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HEI8468660.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            25152..25592
                     /locus_tag="SLE23_001758"
     CDS             25152..25592
                     /locus_tag="SLE23_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEI8468661.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            25608..26309
                     /locus_tag="SLE23_001759"
     CDS             25608..26309
                     /locus_tag="SLE23_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEI8468662.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         8887 a         4290 c         5434 g         7728 t
ORIGIN      
        1 tgggggattt tctcctcgaa ggagtagcct aagaaccagc ggtaagcgac attggtatcg
       61 acttccttaa tggtttgtcg catggaacgg ataccgaata aatactgaat aaacaccaat
      121 ttgatcagaa tcactggatc gatacttggg cgacctaaat cggagtaagt ggcttcgacg
      181 attggataaa taaattcaaa atcaagcgcg gcatcaatct ttcgaacgag atgatcttga
      241 ggaactagat catcaatcgt aagcatcgca aattgatttc taccattcgt attgttttta
      301 gacatcatag ctatcactcc ttgcattcgt tttcataaat ctattataaa agaaaagact
      361 gtagatatca tccataaaat ggactttgtc tacagtctga ggactacctg tattagtcct
      421 cttttttgac cagattttga ccagtctatt ttacattcta atatattcat atgagctaat
      481 tttatgatta aatggtaagt gtttccttgt ttgttttagt ttaaactagt gtgtaattta
      541 aaaatctata tggaagggtc tgtggggtaa tacttaaata aaggctagga acctgataac
      601 atcaaggttc ctagcctttt tataataaaa tgaagcgaaa ataatttctt ttaaagagcc
      661 gagattatca gctatataag agtgaatttg atgcaaaaaa cagagccgaa acagtcttgg
      721 tgttcgtagc tctgcttata tgtttcgaat ttaagacaaa gagttggcaa aagatgttga
      781 taaggaagat aagataactg tgttatataa actaggtaac taactgtaac aagctaattt
      841 taagagattc ttattagaag acgtttagga atataactaa gaaaatgatt atacaggtaa
      901 ttgtcatttc aataatgttt tctaattttc gcgtctttgt tttaagaaaa aggccagaat
      961 cagttggaaa aaagttcgta cgatagtgaa gaggggcaaa atttcctact aatattccca
     1021 ctaacaagag ataaaacggc caggttggtg tgattcctct ataaaaaaat gcccatgcta
     1081 ccgaaatccc atagattaac aactgaacaa tttttacaat gaaaaaattg ttctgccatt
     1141 actcaaagtc tcttcctcct tgtatcgttt atttgtttca ttttatcatt atgataggcg
     1201 cttgaacaat ccattttgta ttttattgag tactcttgga taaactacca gcgattatca
     1261 tatttattta tgttactgta agccatcata taaaagtaaa tgagcagatc atagaaatat
     1321 aaaaaagaac taaaattgat ctaaattatg tgcagcttga ctacgtacca atctatatta
     1381 cttactagat tggtcgttaa tctattcgga tcgaatgagc aaaatatttt tgtgaatgtc
     1441 catccttgat tatgattcca aaaagaatca ttgggaggct gtggcgtaaa tattatacta
     1501 taagccagaa atacctatca ttctgaactt ttttatttag gaactttcat ctcaaggctt
     1561 tttcaattaa tttgtacccc tgttttttgg ataagatcat gtgcattgat tttttctatc
     1621 tctacgttca tctcctactt aatgcctatc tggctcctga gggcttcttt ttaaggcgtc
     1681 gtcatagtct tggctgagga tttcttggta atctgaggga atggcttccc aagtgagcag
     1741 gcgaacgttc atgacgtgtt ttcctttgtg tttgattaca gcatggtttt tctctttttc
     1801 tacctctcca gcgtgaaaag acagccatgt accatggcca aagatatcat tacataccca
     1861 acgttcgatg gaattgtcca cgtatcctac agggagtgtg gtatagccga tttgtggttt
     1921 caaaaaagga ttgaatcgat cgatcgtttc atttttgtat tgataattga taagaaaaag
     1981 atagaccaaa caaaagacga gcagaaagaa agatagtgtc tttttgagtg agaagggttg
     2041 ttttgatgaa taagatttct tgttaacaag aggttcatct ggcaatgttg gttctattga
     2101 ttcggtagct gattcaatag aaggaaaatc aatcggcaga cctaaagtat gatgtaaaag
     2161 tgacagcatt tcaaggtctg gcattgtacg agaattttcc caactagaaa tcgttttatc
     2221 ggaaacacca attttttcgc ctaattcttt ttgcgtaagc ttacaatttc tgcggtaagt
     2281 tcgtattttt tctccggtgt tcatcttctt ctcctttcga ttctacagta tatagattta
     2341 ttctacatga cctatacact tgatagatac gtttttttga tgaaaaacgg tatgatttta
     2401 tcaaagaatc atttaagtaa gggagagtgg tgataatcaa aaaaaagttc acagttttac
     2461 tcacaatcat agtgaccggt atcatgagtg gttttgcctt ggttagtata aataaacagg
     2521 tactctatcg gacaaatgaa tttttccatc aaacagatac ttatactccg attcgattgc
     2581 cacaacattt tattgggcaa gaagaatatg agcagctaat catggtattt gaaaatgtct
     2641 catcagaaac tgagctttct tatatgaaaa aaacagtaaa tgaatccaat gaagtagata
     2701 catcttggaa cttcaagata cagccaaagc ttgaaatgac attgtattat caaggggatg
     2761 tcaaatcttc tcacgagaag gtaccctatt ctaatacctc ctttcgcgta acgtccattg
     2821 aagaatcgat caaaataaaa gattttgaag gtgaattttt cttgatgacg agagaaaaag
     2881 aagcctatga acggttcatt tcactattca ctgatcgatt caatcaagca tttcacactg
     2941 attatgccac taatattttt gaagactttg aaaatagcta ttcgtattcg gttatttcaa
     3001 atacagacgt atataattat cgagtgtatt taactattgg attgattctt ttattccttt
     3061 tgttatcatc ctttttctta ttgatgaata aagaaatcag tttattgttg aataatgact
     3121 tttcattaca tcaagtattg tggtgtttat tggggaaaaa gaaaatcatt attacattca
     3181 taattgcagg aatcattggt ggttttattt ttatgtatta taaggagcaa tttctttatt
     3241 tgttccagat gtacgttttc ttgttcagcg gaatatatgg tatctctttg atttctcttt
     3301 tattagttga aaaaatcgct tcgttaagag aagcgttcaa ctatatccaa tacattcttt
     3361 ttacatttgg attgttgttt tctcttcttt tgaccgttgc caatgtcgaa ttagcaacta
     3421 tcgttttttc ttcttcacag ttagctgttt cccatgaacc accaaaagaa atcgctggtg
     3481 aggactatca tgtattttat ccagtaacca tcgggaaaaa ccacgtggat tttatttatt
     3541 ccaatcgttt tgcatcagca gcagatcagg aattatatga aactttgaat aaaaacggaa
     3601 gtatattagt caatgtatca gattacttga atgaagaaaa tgaacagttt ggcagaggga
     3661 taaaaataaa tctgaattat cttaagaaat ttcctttgat tgatgtctct ggaaggttga
     3721 tccaaataac cgaaaaagaa acgcaccctg ttatattgat ccctgaacga tatagacata
     3781 cagatttaaa aaatgacctg gcgcaaataa cagaatatta tcaagaaatc agtgaaaaag
     3841 aaccgaaatt tctatttata aaaaacaatc aacccattta tacatttatt ccttctatcc
     3901 cctggatcga acattatccg gttgttgaaa tactgacatt gaaaaacagt atgtatttgg
     3961 aaagaaatat tctcagcgga gaaatctatc caccgttaaa gatcaagata ggctctttgt
     4021 cgaaagaaag gttatttgag ctgattgaag aaagtcagtt acgtgataac ttgcagttat
     4081 catttccgta tactcagact gaagagatag ctgtcaaagt gttaagcaga tcatttcatt
     4141 acttgataca gatattttta ctcactttct tttctttctt cttgttgagc tatgtcatgt
     4201 tatgcatata ttttgtctac aattgtcgga aaatcgctat ctttcgttca agtggttatt
     4261 cgctctttga aacgtataaa gatttcttca tgatgaacct catcaaatgg ggaacgacaa
     4321 gtgtaatctt cctttttctt atagaaagag agcctaaata tctttttaat atttttttct
     4381 ttagcttcat tgattttatt ctttcagttg tttttatttt gtctacagaa aagaaaagtc
     4441 agttattgct gatgaatgga ggttaacaat tggagccgtt gatagtgata aaaggtgcga
     4501 aaaaaatcat tcgaaacaaa acgattcttc atttggatcg tttcactgcg gatgctgggg
     4561 atcttgtgac tgttgttgga gaaagtggag caggtaaaag tacgttattg aatatattag
     4621 gattgaatga tcagttcagt tcaggacaat tctatttgtt cgatcaagag acgaaacaat
     4681 taactgggag agagaagcgc ttgataaaaa gaaataccat atcttttctt tttcaagatt
     4741 ttgggttgat tgaatatgaa acaatcgatt ttaatttaga tattggattg aagttttcga
     4801 atttaaatgt ttcagataag cgaacagcaa agtatgaggc attgaaaaaa gtaaatataa
     4861 acaagaagct aagtacgcct atctacacat tatctggtgg tgagaagcaa agaatcgcct
     4921 gtgcgagagt cttattgaag aatagcaaaa tcattttagc cgatgaaccg actgggtcat
     4981 tggataaaag aaataaggat aaagtagttg aaatcttatc gcaacaagct tcccaaggta
     5041 cgttagttat cgtagtcacg catgatccat atctgaccaa aataggaaac aagaagatca
     5101 tgctttaaaa atcaaaaagg aaaggatgtc gttttatgaa aaaagcagtt attatttgtg
     5161 cactagggat aggttttgtt ggaggaaacg ctatgtcatc tgaagtggaa gcaaattcag
     5221 ttcacggtga aatctattac aaatctttaa agccaggaga gattcatttt gatgctaaag
     5281 gtaatattat taagtcaaat ttaccagtag accgggaaat ttctagaaca gcaattaatc
     5341 atagctctgg aagatgggtt tattatagtg atacaacttg tacgagaaaa acaggtcatt
     5401 ctaaccacta tagtcgtgtc tataatcgtc acggtgcaaa agagaaagtt ggaaactcta
     5461 ttcgatcagc aaatgcaaca aaaggagtat gggcctatgc aagtgcgaca ggaaatagaa
     5521 ctgacacatt ctcatgttgg tacaatccaa ccggttggta ttaagtatcc aaaagtttat
     5581 ataaaataga aaaaacatat aatgaaacag cgttaaaagt tatttttggt agttttaata
     5641 tattcatttt tagttgtata aaaatatatc ataataaaaa caacaaaaaa atgtctggaa
     5701 aatcgaacat aaaagtgtct gatttgaata tcccagcagc ggaagaagaa aaacaaaatc
     5761 gataacattt gttctaagaa ttagttacgt taaatacgga acgcaagata gacttgaaaa
     5821 acggtaacaa aagaagtagt atattaaggt gtgatgtgct acttgacatt tattctgctg
     5881 agcgaacttt ctggattgtg tagccttata tctattcagg acgtatcgag cagattagta
     5941 aaggtgttct tgatgatttt catcttgaac acctttgttt ttagcaattc gcaaaaaacg
     6001 aaaagtagga gaattgataa atgaaaaaaa gatttttagc acttgccatc gtactaggca
     6061 ctggcttatt gtcaggctgt acgaatgccg gtgaaaaaac agccgttagt tataaaggcg
     6121 gtacaatcag cgaacaagaa gtaatggata gcttgaaaaa aatgcaagga gcagattccg
     6181 ctgtgcaaca gttgatcgtt tatcaagtat ttgaagataa atatggagat gacgtatcaa
     6241 ccaaagaaat cgattctcaa tatgatcaaa caaagaaaca attgggtgat tcatttgatt
     6301 cacaattgaa atctgcaggt tacacagaac aaacattcaa agacagtatc aaacaaagtc
     6361 tagcctttca agaaggtcta aagaaacata tcaaattgac cgatgaagat ttaaaaacgg
     6421 cttgggaatc tttccatcca gaagtggaag ctcaaattat ccaagtagca agtgaagatg
     6481 atgcaaaaga tgtgaagaaa gctgctgata agggagacga tttctctaaa ttagccaaag
     6541 acaagtcaac tgatactacg acaaaagaag atggcggaaa agtgaaattt gattccacta
     6601 ctacaacggt tccggcagaa gtcaaagaag cagcctttaa gttgaaagat ggtcaagttt
     6661 ctgatgtgat cacttctacc aatgcttcaa cttatactac ggaatattat gtggttaaaa
     6721 tggtgaaaaa ccaaaacaaa ggcaacgaca tggataaata caaaaaagaa ttgaaagaaa
     6781 ttgcaacaga cacaaaatta agtgacagta ccttccagaa taaagtaatt ggcgaagtat
     6841 tgaaagacgc taatgtaaaa atcaaagaca aagactttga aaatgttttg agtacattca
     6901 cttcagattc tagtacagca agtagtaaat aagcggtata aataaaaaat atgaactatt
     6961 taaatcaata aaactgttca tctaaatctt tttattagaa ctaaatcaac agtagtttaa
     7021 ttactacttg atttagttct ttttatttta aaaatttttt ttacttagaa tccagcgacc
     7081 ctagatattt ttctgtataa tcttaaataa agaaaacaat atcaaaaaat gcacgtagaa
     7141 gtagataaat ggagtggttt tgcaaatttc ttttatttct agaagttatt cacgtatacg
     7201 gatttgtttt tctcacaaat aaaaaggcag gaagtacaat ggatcatttg tatataaaat
     7261 atattcatca attttccgtt ttggtgttag gcacactaat tatagcgggg attgtcgcat
     7321 ttattattca aggccgtgac atattaacag tacatcaaga gtttttcagt tatgcatttg
     7381 gtattcctct gatcgctata aggtctgata acaaaaagtg gaagaaacgc tattacattc
     7441 tcttgctatt tttgtgtttt tatctgccac ctaagatttt tactttatta ggtatacaat
     7501 gcctatcatt ttcttttatt tcctatatca ttgttttaat tttcctcagt ttcatagtat
     7561 ggatgtttta tcttgtcaaa aaataaatga atgtttcatg aacagtactt catcacagcc
     7621 taattttttt ctttatgcta tcgttatatt aaagaaatca atcagaaggg aaagaaagtg
     7681 atgaaaaaag ttttattagt ggtaaacccc agttcaggcg gtgaacaagc aaaggaattt
     7741 gagcaattag cgatagcaaa attggaatcg gtgtttgatg aagtggtcgt cttgcataca
     7801 aaaaaagcag gggatgcaaa aaactttact cgcgaagcgg ctacggaagg gtatcatagt
     7861 gtgtttgtca tgggcggaga tggaacagtc aacgaaggaa tcagtggaat cgctgaacaa
     7921 gaacatcggc caaatttcgg atttttccca ttgggtacgg tgaatgactt ggctcgagca
     7981 ttagggatac cgctagaacc tgaggaagcg atcaatcatt tttcgattga atcagtcaag
     8041 ccattggata ttggaaaaat aaatgacgac tattttatga atgtcgtcgc aattggctct
     8101 atccctgaat caatcaatga tgtagatgcg gagaagaaga cgaaatttgg aaaactagct
     8161 tatttcatgt caggaatcaa acagttagct tccacacaat cctactcgtt tcacgtagaa
     8221 gttgatggaa agaaggaaga aattgagagc agtaccttgc tgataggact aactaactca
     8281 gtcggcggtt ttgaaacatt acttccaaat gcaaaagtgg atgatggtaa gctccatttg
     8341 gtttatttaa aagattcttc tttgatcgat acgcttaaaa cattgccaga cctattaaaa
     8401 ggagtagatg aatctacgaa aaatctagcc taccttactt gtgagcaatt agttgtgtca
     8461 ttagctgatg aggaagaatt gacgacgaat gttgatggag atgaagggga taaattacct
     8521 gtgacaatca aagtattgcc ctcacattta caggtttatt gttaaaatgg aggttgtgac
     8581 cgaggagttg gcgggagaac accgcttgtt cgggataagg gactgtgaca agacttttgt
     8641 cacagccttt tttttgtaca aaaaagaaat ttacacctaa tagaaaaatt tttccataaa
     8701 aatacatatt ttaaatatga aagtacaatt ggaaatagat taaaacgata aaataaaatt
     8761 gtcaaaacgt cagagaggat ggtggagaat gaatcaatgt gtaaaaaagc tgattgcgtc
     8821 gattttgttt gtcttccctc tcttgatggt gacatccgtt tttgccgatg tagagaaaac
     8881 aaacgaatca acgcaatcag agaatcaaag ttttgacaag actacttttt cagaagaatc
     8941 gattacttct gaaactacag aatctcaaag tgaggcttct actaataaaa ggcaagaaga
     9001 aaataagaca agtgagacct cagaagtagc tgaacaaacg tctgatagca gtgaagcggc
     9061 actggcaaga gctgtttcag cggatgggta cagcgaagct gccacaacag aagaactggc
     9121 gcagcttctc gcagacgaat cagtaactaa gatccgactg attcagcctt tgactttaga
     9181 cagggaatta gagatcaaac gagatatcgt tattgatttt ggtggattcg ctcacaattt
     9241 cggcacacac catatttata tcaatgagat acctcagtcg atcgagttcc agaattttaa
     9301 aggaacagct gcacatccag gtggattgac accaaatatc gatggaaatg ccattatcat
     9361 tgcttatatg accgattttt ggggaagcag atatcatttt acgggagaaa taaaatttac
     9421 cgggacactt gatttgtatg atgggtccaa attaggactg atttacgctc ctcgtgcaac
     9481 tgtcacatta gatggtgttt ccggtgtgtt ggatgtccaa ccagtgaagg aaggactgaa
     9541 tgccgctccg ggtaaagcct atttttgtag aagctatcaa ttgaatgtga tcaatggtag
     9601 tcaactttat ggaccgtatc tagggaaatt ctacggtttt ctagattcag gagatgagac
     9661 tggtagtgga aaaacagcgc caggaatcca tatcttaagc ggttcaaagg tctctcttga
     9721 ttatgatcgg gcagatggcg ttagcgatga aggagaggca gtcgatacgc tacctggtaa
     9781 tgtcatgttt gaagtcagtg gttcgggaag cgaattttcg gtaaatacaa agatcaatat
     9841 taccaatgac aacaatcgcg gaatcatcca aatgagaggt tcaggatcga aagtcactgt
     9901 atcgaatggt gggaaaatca ccatcaatac agcaactacg ggcggatttc gcttgcaagg
     9961 agattctagt caaatccatg tatcaagtgg tggacaaatc tcggtcaaaa tggctggaga
    10021 tgacgatcaa cccgggaaca atgggatgcg ttttgtagga aaaggccttt ctttgatcgt
    10081 agaaggagcc ggatcagtta tcgacatcga taagcagagt gggcgttcca gcgcagttcg
    10141 ttttgagaat ggtacgcaaa agctgacagt aaccaatgga ggctcattga gggtaagaaa
    10201 tacaggtgat ggcaaatctt acgtgaacag actcaatcaa ggaaatcaag cgatccaatt
    10261 ttatgacgct tctggttttc tagaaagtcc aggttcagct gattttacag tcactggaga
    10321 aaaatcaaat atcgatatac gcgcagattc cggagcaact gtagatacaa ctggagatat
    10381 tgatttaaat tttacggcag gtgaaaaaac ttatttagtc atggtcggga aaacagggga
    10441 agataagacc ggcatcatca gtggggatgt gttgaatgtg gacttagaat ctcctaccta
    10501 ttttgatttc caaaacaaac ggattggaag cgagaccaat ggcataggcg gctgggtatt
    10561 ccaaggaaat ggagattctt ctttaaagat cgcccattca gaaatcgctt tatggcgaaa
    10621 aacaggcgca acattcgata actttgaaaa agacccggat tatttttctg atatgacaga
    10681 cttatcgatc aatgggaccg acttaggcaa tttcgtatca agccctagtg caggtttaac
    10741 aaatgaattt gctcagacag gtgccggaat gaaaaattat aatcgaatca gtgccaataa
    10801 tcagctcccg atgattgaat ccttaagagt gccaacgaat gcagataaaa aaatctatgg
    10861 gcatgtcgtt gttcccgaag gtgtcgaggc aaagccaaga gatgcttgga caggcgaagt
    10921 agaagtgact ttacgtatta cttacgcaga tacgacgaaa tcatctgtag aaattactgc
    10981 tctcacgcaa ggacaaacag atgaaaatga aggggcagga tataacccat ggggagaagg
    11041 cgaacaaggc ggcttgttcg aagttcaagt acccaatgat gagagattaa aaacggagga
    11101 tcaagtgcaa gttgttgctg ctaaaaaagt aagaggtggc caagaagtga cagaactgga
    11161 ctctgccaaa acgacagtcg atgtgattcc tcctgaacct gctaatttaa gtaccacatt
    11221 gatcaatgca gcttctcgca cgatcacagg tacaggtgaa gcaggagcct tggtttcatt
    11281 gaaaaaaaat caagctgttt tgtcagaaac aactattgat gatacagggg aatttgttct
    11341 ttctatccca gaaaatcaac tttttgcagg agatgtatta gaaattgtat taaacgacca
    11401 agcaggagaa gctactgcta agggtgtgca gaacaagcca agtaccaacg atgaaattgg
    11461 gaatcacaat ccaagtgata cgccagttgt ttatcatgat gccccgcctt ttgcacctgc
    11521 tacgaagatc gtagtagaag gtggtctctc atttcttgcc ccttccaaac tcgattttgg
    11581 tcagatcaaa gcaactggtt tgacacaaga agcatttggc caaatggata tacaggaaaa
    11641 attatggatt tatgatcagc gagaaacgaa aaatccgtgg atcttaacga taaaattatc
    11701 tcagcctttc acaaatgatg caggattttc tatgcaggat gtcctatatt tcaagaaagg
    11761 agaggagtat caattagtga atgaagaaga actggaaatt gtcagaggac aaaattcaac
    11821 gaatgtgcaa gcagattatt cagaatattt aaataacggt cgggcgttta aacttgtctt
    11881 aaccaaagaa aatcagatag ctggtaatta ctcagcagag ataacatgga cattagcaga
    11941 tgcgccgaca gaataaagat caaggaggat gattgatgaa tcgaatatgg aataaaagtc
    12001 atcgaaacaa ctgctcttta cttatgatcc ttctccttgg attcatcctt tggcagacac
    12061 ctgtccatgc ctccgaattc aattttgcgg tagattttga attaccggct aatcagattg
    12121 ataagaacaa aacatatata aatgtaagga tggagcctgg gaaaacacag gaaatcccct
    12181 acacggtctt taaccgaaca gataaatcag taacagttga gacattgatc cactccgcta
    12241 cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa aagtaaattt gatgaaacat
    12301 taagttatga tatgaaaaac ttagcaaaaa cagtgggaga aataactgtt cctcctcaaa
    12361 gtgcggtcac tgagacactt tcactgaaag cgccagaaaa agagctggct ggtgtggtcg
    12421 caggagggat cacgtttcaa gaaaaaaaag agaacgtttc taacaaaagt acagttggtg
    12481 tcgtcaatca gttttctcaa gtgaaagcaa tcttgatttg aaatagcgaa aaagagtctt
    12541 ccccagattt gaaattaaaa aaagcttatg cggatcaaag cgatggaaga aatgtgatta
    12601 aggcgaatct tcaaaatcca aatgcttctt atatgttcgg cttgactaca tcggttgaaa
    12661 tctacaaaaa agaaacaaaa gagccttacc tttcaataaa aaaagaaaaa atagatgtag
    12721 cacccaatac aaattttgat ttacttgtcc cattagaagg aaaaaaatta gctccgggac
    12781 attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg ctggaatctc cataccgatt
    12841 ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa ggatattgat ttaaaaaatc
    12901 agccagaaac atttgactgg cgatggctga tacttgttgg agtcattctt attggcttat
    12961 ttgctggatt atttatttta aaagaaagaa ggaaaaagaa atgaaaaaaa caattgcatt
    13021 aagtaccgtt ctagctggaa gtctattatt atgtacacaa agtgtttttg ctgagaataa
    13081 gagctcagcc actacagaag gaacgatttc tgtgaccaaa ccagatgctg caaatcctga
    13141 agacgttgtt ccagttcctc ctgttgatcc aaatgatcct gatactcctt ttacacctga
    13201 cgaaccaaat cagggaacat ccggattact gacgattgac caagctccag atcttgattt
    13261 tggaacaatc aagttaggta cagcaaaaac agtatatgct gcattacaaa gcggaacgga
    13321 cagtactgga gcacaaacac aagtacagaa tttcgtacaa gtaacggata aaagcggaaa
    13381 ttatgccggt tggaaattat cagtcaaacg aacagaattt attggtacaa catctgatac
    13441 gaataaacta actggttcaa aggtgaaatt caaaaacgcc gtgattcgaa atagcgcaac
    13501 taatagcagt ggaatgccat ctaccgtttc tggaactggc gctgaaggaa tcgaaatccc
    13561 agcagatcag gcagtagatc tagtaactgc aggagcaaat gaagggattg gcacatggat
    13621 ttattcatta ggagagaatg tggaacaagg gagacaatca gtggaattat ttgttcctgt
    13681 atccaattat gctgtagaca actacgtttc aacattcaca tggtcgttaa cagatgctcc
    13741 tacagaagag gaagcgtaaa atcatatcaa cgatttcagg gagtggagcc gattcaaggc
    13801 ccactccctg aaatctgcta tgcttacgtc tcagctctta ttcatcaact cgaagcagtt
    13861 ttttggaagt catggaaacg ttcctttgtc ttttcaaaga tctttcgacc aacgagtaag
    13921 gagtcaccgt tgaaaaattc taacacataa tgagcagaat caattttctg caattgcgat
    13981 aagttgatac agtaagattt taaaagtaaa aagtaagcat acttttctaa ctctgtcttc
    14041 aattgtttta aagaagtatt cactaattta tcttctgtag ttgttttgac cataacttgg
    14101 tttttcaaac ctttgatact ttcaatatat aaaatttccc gaggatacag gacgagactt
    14161 ccaccttttt gatcaataaa gattttatcg acatttacga tctgctgttc tttccaattg
    14221 atctgttcta gcacttgacg aatttgttca gataaattcc tgtcttttct gatatatcca
    14281 atcggaagga ttttccgatt gatgatctct actgcaaaat tcgtataagc ggtgaaaaaa
    14341 acaatattac tatgtgcatt ttttttacgt atttgttcgg cgacatcaat acctgtgagt
    14401 gattgcttca agtcgatatc gataaagaaa acatcgtgat tatcaatagt gcccaactgg
    14461 atcaactgat tgatttgaga gatagaagtg agctgcacga tattctcgat atgatgattg
    14521 accaattctc tgatgatcca ttcgctgtga aactggttat cttctatgat aaaatacttt
    14581 ttcatatgca ggctcctatt aaaaaaatat gtgtacattt tgaaacaaaa caatggagga
    14641 ataagatggt cgcaacagtg acactttatt tgacctttac tttgatttta gatttaggta
    14701 tctatttatt cttttcgaaa caactgctag taaaaaacag ctttggttgt atagctttga
    14761 tggtggtgac acttttactt cctatcccta aagtgagctt tccttaccta gttggcttat
    14821 tattgatgtt tcttttttat tttactacga aaaacctgtt tatcagctgt ttgatcagta
    14881 atcttttttt tgctatcact ggactcagct tttttctggt ttttgatctg atggattatt
    14941 taggaaagag acatcttgga acagcaagtt tttttgcact acttatcgca tttattttct
    15001 atctattagt aaaaagtata gacaaacaga cgagatttct caacttgctt tttacttatc
    15061 caactgaaca ctattttgga ggtatttgta ttttattaag ctggggcgtg atttacttgg
    15121 tattgggaag tgttcacttc cgctcatcta attatctgct tctatctctt ttgtcgatag
    15181 tcatcagttt tttttctttg tttttttcca ttatgttgat cagtttccaa gtaaaagaaa
    15241 gacaacatca ggaatcgctt caactgtatc aaataaatga agaatattac catcatctag
    15301 aggaattcaa acatgattat aaaagtctac tgttttcatt aaaaattact cttcaggaaa
    15361 ataaaaaaga aacgttggaa tttttagaaa tattagaaga tcattctgca gctatttttg
    15421 aaaaaccgca aatacaacag ctaacaaata ttgtatcccc agctgtcagg ggtgtctttt
    15481 taaaatttct agaaaaagca gaatcggaga aaatcccgat ccaagtagtt attcctgtcg
    15541 aagtgaaaac aatcccgatt gatctggttg tttttattcg ctgtttatct atttttattt
    15601 ctaacgcatt cgatcatcgt gtagccgatc agagtccgat tacgatcaat ctgctggaag
    15661 aaaaagaggg atcacgtttt agtatagcga acaaggcaaa tccaacgaat ttgacgctat
    15721 cggagatggt caaaagagga aaaacctcta aaaaaaatgg cgggttaggt ctatacagtg
    15781 cgaaaaaaat gttggatgtt tacgaaaatg cagaactaaa aatcgaattt tcaaaacaga
    15841 atcactattt ttttgtagaa atgtatctgg catctagaaa gagcaaatca gcctactgac
    15901 ttactgtcaa aggataagtt tgaggaaagt ctacacggag atagagacaa caacacagca
    15961 tattcaaaag aaacagaagc gtgatgaccg ttgtcaccct tctgtttctt ttgctatgta
    16021 gttaaacaaa gtagttgaca cttccgctac ttagtattag tacgaaagta tacttcatga
    16081 tactaagtag ataagaagtg aaaagcggaa cccacgatcg tcaaaatgct aactgctttg
    16141 cttacaccag ataaagggaa gagcaatatc gcttatttta ggcgtggaga agcaagcaaa
    16201 tccctacgat cacaaaaaaa atgctgaccc agcagttaag agagttagaa caagatgaaa
    16261 gtatccatcg aaaagcctat aaccaagtcc cgcctaaagt agagtactcg ctcaccgaag
    16321 aaggaaaatc attaagagag attctagtag cgttgtctgt ttgggaagaa gaacgtatcg
    16381 aaaaacaaaa agcctcaagg gaagaagaca cgctactgca tacacatggt ggctacctaa
    16441 attattgatt ttctatgaca tttattttaa ataaaagaaa acaggagttt ttttaaaagc
    16501 atcatctatt ttttatgtaa aaaaatggta tgattaatca agtaagaagt gattggaaga
    16561 aggcaagcaa atgaatagta tggaaaaagt caaccagttt agagatgaac gtaattggcg
    16621 acaatttcat aacgaaaaag atttggctat ctctatttct ttggaagcat ctgaattgtt
    16681 agaacttttt caatggaaaa cgccggaaga agtaaaagaa acacaattag aacgaatcaa
    16741 agaagaactg gcagatgtat tgatctattc atacatgatg gcagacaacc ttcacctgga
    16801 tctagatgag atcattgaag aaaaattgat caaaaataat ttgaaatatc ctgtagaaaa
    16861 aagcgcaggt gtacgaaaaa aatacacaga gttgtagaaa tgtgtcattc ggctgttgga
    16921 aagagcaaaa gaaaaacagt aaaatgagtc tggagggaga gaaaatgaaa aaaaaaggaa
    16981 aagcaaaaag atggctagtc aatatcctct tgttcctctt gttattagta ggactagctt
    17041 tgattttcaa tgaacagatc aaggattatt ttgtcagaga gacaggagat aaatatgcta
    17101 tagcgaatgt aacaaaagaa gatctgaaaa agaataacga taaagatgtc agttttgact
    17161 ttgatgcggt agaaccaatg acgacagaag gggtcatgag gtcgcaaatg agaggaacag
    17221 atctaccagt gattgctagt atcgcagtcc cttcagtttc aatcaattta ccggttttca
    17281 aaggcttgga taatacgtca ctactttacg gagcaggaac attatctcca gatcaagaaa
    17341 tgggaaaagg aaattatgcc ttagcaagcc atcgtgcaac gaaccctgaa ttgctgttta
    17401 caccgctaga aaatttagag atgggtgcca agatctattt gacagattta gaaaatgtgt
    17461 atacatacaa aacatttttt aaagaaaaag ttgctcctac agatacccaa ttactgaatg
    17521 aagtcgaggg aaaagaaatt gtcacactaa ttacttgtgg cgacatggac gccgtcacgc
    17581 gactagttgt acaaggagaa ctggaaagtg ttacatcgat aaaagatgcg acagatgata
    17641 tgagatctgc tttcaatcta gagacaaaaa cattttagga tactgggaca taagtcgtta
    17701 cagattaaaa acagccaaag gatatgaatc gataaggaaa aaccaatttg ctgaaaaaaa
    17761 gagaaacgca aagaggtgca tctctgattt ggttgttttc tagatagact tgtgttccag
    17821 tttttttatt ttttatatga aaaggcttgc ataaataaaa attcgatggt atgatgattt
    17881 tgaataagaa atggattgtt actgtacggc aggcaaaacc agaattcagc taagaaacag
    17941 taggcgaatt ctaggttttt ttatttttct tgagagggcg aagcaaaatg aaaattgata
    18001 aaattttgaa taacaatgtc gtcatttcga aaaatggatt cggggaagaa gtcgtttgta
    18061 tgggaaaagg actagctttt caaaaaaaga ttggggacga gatttcgcca gaagcggtcc
    18121 aaaaagaatt tgttttaaga gattcttttg ctaaaaacca attccagcag ctgatggctg
    18181 atattccggc agaggagatc gaatgggtca aacaagtagt cgaactggct gaagataaac
    18241 taaaagttga attttcgcct aatatttatc tgacattgac cgatcatctt cattatgcga
    18301 tcacacgagc aaaagaaaat atccaactgc ctaatccatt attatttgaa acaaaaaaat
    18361 tttatccgaa agaatatcaa gcagcgaaag aggctctttt gttcgtgaaa caaaagacgg
    18421 gtgtggaact ttctgaggat gaagccggtt ttattgcctt tcattttgtg aatagccaac
    18481 aaggaaacga agacatgcaa gtgacgatga ccgctaccac aatggtaaga gatatactga
    18541 gtatcatcag taaattcttc ggcatcgtgt tcgatgaaga atctttgaat tatcagcgta
    18601 tcattactca tctgcagttt tttgcccagc gttatctcaa aggggaagga tctgacgagc
    18661 aagatgaatt tctctacgca ttagttcaag gaaagtatcc aaaagcgttt cattgtgtcg
    18721 aacggatcaa tgagtatctt cgacaaacgc aaaaacagga aatggggatc gcagagcaga
    18781 tttatttaac gattcatatt caaagagtag taagtgagaa aaaaagcatc caatcataag
    18841 gattgttact gtatggcagg caaaacctgg attgaaaaaa taggttcacg aatgtttgtg
    18901 actgtttttt tcaatctggg tttttatttt ttaaataaaa aagaaagaag gaaaaaacaa
    18961 tggataatca agcagttggt cgtcgtgtat gggaagcggt aggaggacaa aagaatgtca
    19021 aaagtttagt acattgtgct acgcggttgc gattcagatt aaaagatgaa tctttagcag
    19081 atacgcaaaa gttaaaagaa gacccggacg tgatccaagt cgtacaaagt ggcggtcagt
    19141 atcaagtagt gattggcagt aatgtagcag atgtttatca atcgatcgtg gatgaggaag
    19201 gtcttgcagt ttcggaggat ggaaaagaag agtccaaaaa tattttgaat cgtctgatcg
    19261 atattatctc tagtatattt acaccttttc taggggcgat ggcagccgcc ggggtattga
    19321 aaggattctt atcattggca acggtgatgg gctggctgac agctgatagc ggtacttatc
    19381 aaatattgtt tgctgcagca gatggtgtct ttaccttctt acctgtcatg cttgctttta
    19441 cagcagctaa aaagttcaaa gccaaccagt ttttagcagt agcaattgct atggcacttg
    19501 tgtatccagc tatcacagca gttgctggtg cgggagaagc tatcagtttc tttgggatcc
    19561 cagtgattct ttcaccatct ggttatactt cttctgtcat accaatcatt ctagccgtat
    19621 gggttcaaag taaattagag ccattcgtaa aaaaagtgat tccgcaattt ctgcaaatga
    19681 ttttagttcc gcttgtcgtt ttagtagtga tggttccatt aacatttctt gctttaggac
    19741 caatcgggac ggttgccggt aatgctttag gcggtctctt caactcgatt tatggattta
    19801 gtccaatcgt agcaggtcta atcatgggaa gtttatggca agtattcgtg atgttcggca
    19861 tgcattgggg attcgtaccg atcatgtttt tgaatatcga acaatatggg tttgatgtat
    19921 tgatgccaat gcttcttcca gccatcttgg cacaaggtgg ggctgcttta gctgtagcat
    19981 tgcgaacaaa agatacgaaa cttcgagcat tagggatttc ttctacagtg acttcgttat
    20041 ttggaatcac tgaaccaact gtgtatggtg tgacattacc tttgaagaaa ccattcattg
    20101 ccgcttgtat ttctggaggt attggtggag ctattatcgg attttccgga gtaaaagctt
    20161 tctccagcag tttggtcagc ttattgacga ttccgacttt cattaatacg gtggatggtg
    20221 tagagtcaaa tgtgacagta gcagtaatag ctacaggaat tgcttttgtt cttgcattcg
    20281 taggtacatt gattttagga tttgacgaac aaacacaaga caatcaatta gaaaacaaac
    20341 atgcgaatgc aggagaaccg attacttcag cacggcatac cttaaaaagt cctttaacgg
    20401 gtaaagtact gccattgagt gaagtaccag accaagtttt ttcttctggc gtgatgggaa
    20461 aaggtatcgc tattgatcca gaagtaggag aactagttgc acctgcagac ggagagatca
    20521 cgactatttt tccaactgga catgctgtag ggatcacaac gactgacgga gcggagattt
    20581 tgattcatat cgggatggat acagtagaat taaatgggaa tggctttgag atcttagtca
    20641 aacaagggga tctcgtcaaa gcaggagatt tattgattcg ttttgacatc gaagcaatta
    20701 gagcagctgg ctatagcgta atcactccag ttgtcattac gaatactgat gcatttgccg
    20761 atatacttga attagaccaa aaagagatta ttgcaaacga agatgttctg gcaattgtaa
    20821 aataaggagg aaatcaggat gcaatcacgt ttttcagaaa aatttttatg gggtggagca
    20881 actgctgcca aatcaattag aaggggctta tgatcgagac ggaaaaggac tatccgttgc
    20941 agatgctatg cctggaggta agcagcgctt tgcgattatc ggcagtgaag aatttgactg
    21001 gacgattgat caagaaaaat atatttaccc gaatcatcga ggaatcgatc attacgatcg
    21061 tttcaaagaa gatcttgcct tgtttgcgga aatgggattc aaatgttatc gtttttcgat
    21121 tgcctggaca cgaatttttc caaatggaga cgaaggtact cctaacgaag cgggattaga
    21181 attttatgat cagctgattg atgagtgctt aaaatatgat attgaacctg tgatcacgat
    21241 ttctcattac gaaatgcctc ttcatttggc aaaagaatac ggtggctgga aaaatcgaaa
    21301 actgatcgac ttctatgaac gatttgctca gacagtatta gagagataca gcagtaaagt
    21361 caaatattgg atgactttca atgaaatcaa ttcggccttt cactttccag ctttaagtca
    21421 aggattagta aaaagcaatg gagcaggaga gtaccaaaat attttccaag catggcataa
    21481 tcaattcgtt gcaagtagca aagccgtaaa aatcggccac gaattgcgtt cggatatcca
    21541 aatcggctgc atgattatct atgcaacaac ttacagcatc gatgccaatc cagtcaatca
    21601 ggcagcaaca atgatccaaa accaagaatt caattttttc tgcacggatg tccaagtacg
    21661 tggagaatac cctgcataca cagcgcgtac ccataaaaaa tatggagtcg atccggaaaa
    21721 attagagcaa acggaaaaag acttccagtt gctaaaagaa tatccagtgg actacatcgg
    21781 atttagttat tatatgtcta cggcaatcaa tgagactgat ccacaagcag caacttcaga
    21841 agggaacttg ctgggaggag taaaaaatcc gtttcttgag gcaagtgaat ggggctggca
    21901 gatcgatcca gaagggctga gaatcgcatt gaatgaatta tacaatcgtt accagaaacc
    21961 attattcatt gttgaaaacg gtcttggagc cattgatcat atggaagagg atggcacgat
    22021 tattgatgat tatcggatcg attatttacg tcgtcatatc gaagcgatgg ctaatgcagt
    22081 agcagacggt gtagatttga tgggctatac gccttgggga tgtatcgatc ttgtcagtgc
    22141 atcaacagga gaaatgagta aacgttacgg ctttatctat gtggatctag acgatgaagg
    22201 aaatgggaca ctgaatcgat caaagaaaaa atcttttgat tggtataaag aagtaattgc
    22261 ctcaaatggc gtaaacttgt aattaaagca gctgaatgaa aaagaacaca cttctcacat
    22321 gtgatttgtg ttcttttttt attttttatg tgctattctt ttagtaatag taaagcaaag
    22381 ggtgacgtta tgaaaaggac acgtgtacta tacttggaag tcgcagataa aattaaagaa
    22441 gatattttct caggaaaata tccagtcggt tcgatgttgc cgacagaaag tgaattagaa
    22501 gaactgtttc aagtcagcaa aatcactgtc cgaaaggcaa tcgaactgct ggcatcagat
    22561 gaatatgtcg caaagaaaag tggtcgtggg acgacggttc taagcaatcg tccttacaat
    22621 cgattatcca aagcggcaag ctttacgcaa atcttggaga actcccgata tgaagtccgg
    22681 aaagaaacgc tggatttgca attggtccat ataaagaagg aagatccttt gttttccttt
    22741 ttcggtgagc aagctgtttg ttttaagcgc ttatattatt tgaacaatca gccttatatt
    22801 tattttgttc attatcttcc acaagaaatg atgcaattca gcagagaaga atttggcaaa
    22861 gaatctttgt atcgtttgct gacgaaaaaa ggatatacta ttgactcatt ttctgatgat
    22921 ttctcggcag tatttttaac agaagaagaa caaggaattc tgaaaacaga cgcacagatc
    22981 ggcatcaaac ggatacggaa atcgtctacg caaattgggg aaatgattga atattcggag
    23041 gcggtctacc atacggagct gcatccttac catattgatt atgaaacata aataaaaaaa
    23101 gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagcttc
    23161 tcatattttt cgtttggtta ggcttattac cgcagataca cggctgtttc tggattacca
    23221 tttattctgg ataagggggt gtggcacgat tttcagaagg aatctatgaa ccaatcactg
    23281 tattgatttt agcttcgatg gtaaccccat tcggcttgac gatcgcttat ttcttaggga
    23341 aaatcattcg taaaaatata ctcaatcgtc aagaaatcga tacattgaag accgcttttc
    23401 ctatggggat ctgtcagatc acagagggat gtttccctat cgtattgaac gacttggcac
    23461 gcaatgtcat agcaacggga gtcggtggga cagtaggtgg cggattaagc atgttttggg
    23521 gcgcagatag ccgtattccg gcatcgggaa tgtttgcagt cgctacgatg accagaccat
    23581 gggcattcat tggtgcattg ttagctggtt cttttgtcac aggaataacc attttattat
    23641 tgaaaaaacc agtagatccg aatgcagaaa tcatccaaga agaaaaagag gaagaagaca
    23701 tatcttggga tgatttgaca attagttagg agaggcagaa tggattacaa gaaaaaagta
    23761 caatagatgt accttgagac aggaatggta tgaaagaatc agagttagaa agaatcgaat
    23821 atacagattt tggtttagga gcgatcgaaa ctgtccagag catcggcacc ctccttgaaa
    23881 tgacgatgaa ggaaaaatga gaacctttcg ttgtcgaaag ggtctggtat accttatgtc
    23941 gaaggaaagg aaacaaaaaa actttcctgt actattccaa aaaggaaaga aagttattat
    24001 acagtaaaaa aagaaattat tcttcatgct agagatcagt acacgttcga gcccaatatc
    24061 aaacactagt tccaggcagg cgcaacaggt gcggttatca ctgaattttc ttccagcagt
    24121 gacgattcaa gtgatatttt tacaaatcca gctatttatc gttaacaaaa agatttttag
    24181 gagaagctga tgaacaaaaa tgatcaaatt ttgatcgttt agttcgtcgg cttttttatt
    24241 tagagaaaca tcatttatca gtgaaacata acacgagaac aaaatgattt tttcgttaat
    24301 aaaagaaaca agtatttgtt gtttaaaata atacacgtta ttggcatata ggacgaaatc
    24361 ccagtatctt ctataagtaa gtcatttcat atcgatgaaa acacgttatt tatttttgtt
    24421 ttatctataa aatggctgaa aaatgatttt tttctaaata ctatatatag tggcgtctat
    24481 cctatatacc actaaaaaac tacaaaatct agtcttttat tttaaaaaaa cacgtgtaga
    24541 atgaagatag acttttgagt tagggagtgt ttttttatga aacttactgt tttttgcggt
    24601 tcccgttttg gtaataaaga aagttacaaa tttattgcgc aaacgttagg aaaatacatg
    24661 gcacaagaag aaatcgaact ggtttacggt ggttcatact ccgggattat gggagtgatt
    24721 agtaaaacag tactggaaaa taacggaaaa gtcacaggta tctatccgaa tgggcttttt
    24781 gaaactgaat tgcctggaaa agatgttact acatttattc ctacagaaac gatcgatgaa
    24841 agaaaggtat tattatttga aaagggagat gctgtcctcg ttttccctgg aggtctaggt
    24901 acattggagg aattctcaca acttctttct tggatagcaa tcggtctgac gcccgacaag
    24961 ccaatcggaa tattgaatat tggcggttat tacagcggct tgcaacaatt attagaaact
    25021 tttgcaaaag aggattttat ggataaaaaa tggttggatc aagtaatctt ttccaacaat
    25081 ccattggaac tggtcaatga attacgagca gtatctatta aaaatcagtt attattgaag
    25141 gaggcaaaat aatgagtcaa atatatttag caggaccatt tttttcagag gagcaaatcg
    25201 atcgagtaag tcgtatcgaa aaagcgttgg aggaaaacaa aacagtcaca agtttctact
    25261 ctccacgtca tcaccaagaa agcaattatg aactattcag cgctggatgg gcgcaggaag
    25321 tatacgaaaa agatatggaa gaactgacaa atgcagaatt tgttgttgct atccttgact
    25381 ttgagcatca aacaatcgat ccaggaacgg cttacgaatt aggtgtggca actatgttga
    25441 aaaaaccgat gatcattgta caagaagaga cggtacctac gaacttgatg attacacaaa
    25501 gtctccatac gtatttaaaa tcagaccaag ctgtacgtga atatgatttt gaaacattgc
    25561 ctgttgaaac ttacgtaggc gagtacttat agaagaggaa gggttgtatg tcagtgattt
    25621 tgatttcagg aacgattggt gcaggtaaga gcagtttgac ggatatgctt gcaaaagaga
    25681 ttgattctaa accattttat gaaaatgtcg aagataacga agtattgccg ctcttttatt
    25741 caaatcctga gcagtacgct tttttattgc aaatcttctt tttgaacaag cgatttttag
    25801 caatgaaaaa tgctttagtg aacgatgaca atgtgctaga ccgatccatc tatgaagata
    25861 gcctgttgtt ccatctaaac gctgatttag gtcgggtaac ggatatcgaa gtacagcagt
    25921 acgatagctt attagatacg atgctaaacg agttagatga tgttgctcca aaaaaacggc
    25981 ctgatttgat ggtccatatc aaagtttctt tggacacgat gctagaacgt atcaaaaaac
    26041 gtgggcgtga ctatgaacag ctagaaagcg atgagacgtt atatacctat tatgaaacgt
    26101 tgaacacccg ctataatcaa tggtatgaag attttgatgt atgtcctaaa atacaagtgg
    26161 atggggataa attcgatttt gtagaaaatc cagaagatgc aaaaaaggtg atccgtcaga
    26221 tccaagaaaa attagctgaa ttggaaggaa agcctgctgg aaaatatttt acggataacc
    26281 agcatgcaaa aggtcaagaa ttaggctaaa aataaaaaac caaacgacgg gaaagaaaa
//
LOCUS       DARPZJ010000035        25809 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.036, whole genome shotgun sequence.
ACCESSION   DARPZJ010000035 DARPZJ010000000
VERSION     DARPZJ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.036"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            9..851
                     /locus_tag="SLE23_001760"
     CDS             9..851
                     /locus_tag="SLE23_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEI8468663.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            851..1798
                     /locus_tag="SLE23_001761"
     CDS             851..1798
                     /locus_tag="SLE23_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEI8468664.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            1813..2046
                     /locus_tag="SLE23_001762"
     CDS             1813..2046
                     /locus_tag="SLE23_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HEI8468665.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            2377..2961
                     /locus_tag="SLE23_001763"
     CDS             2377..2961
                     /locus_tag="SLE23_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8468666.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            3092..3759
                     /locus_tag="SLE23_001764"
                     /pseudo
     CDS             3092..3759
                     /locus_tag="SLE23_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            3770..5185
                     /locus_tag="SLE23_001765"
     CDS             3770..5185
                     /locus_tag="SLE23_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8468667.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            5203..5772
                     /locus_tag="SLE23_001766"
     CDS             5203..5772
                     /locus_tag="SLE23_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEI8468668.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            5882..7636
                     /locus_tag="SLE23_001767"
     CDS             5882..7636
                     /locus_tag="SLE23_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468669.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            7596..9362
                     /locus_tag="SLE23_001768"
     CDS             7596..9362
                     /locus_tag="SLE23_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468670.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            9885..10154
                     /gene="rpsN"
                     /locus_tag="SLE23_001769"
     CDS             9885..10154
                     /gene="rpsN"
                     /locus_tag="SLE23_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEI8468671.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            10169..10348
                     /gene="rpmF"
                     /locus_tag="SLE23_001770"
     CDS             10169..10348
                     /gene="rpmF"
                     /locus_tag="SLE23_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEI8468672.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            10380..10757
                     /locus_tag="SLE23_001771"
     CDS             10380..10757
                     /locus_tag="SLE23_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468673.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            10778..10927
                     /gene="rpmG"
                     /locus_tag="SLE23_001772"
     CDS             10778..10927
                     /gene="rpmG"
                     /locus_tag="SLE23_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEI8468674.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            10951..11934
                     /locus_tag="SLE23_001773"
     CDS             10951..11934
                     /locus_tag="SLE23_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HEI8468675.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            11964..12086
                     /locus_tag="SLE23_001774"
     CDS             11964..12086
                     /locus_tag="SLE23_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEI8468676.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            12104..13627
                     /locus_tag="SLE23_001775"
     CDS             12104..13627
                     /locus_tag="SLE23_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEI8468677.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            13651..13890
                     /locus_tag="SLE23_001776"
     CDS             13651..13890
                     /locus_tag="SLE23_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468678.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(14083..14544)
                     /locus_tag="SLE23_001777"
     CDS             complement(14083..14544)
                     /locus_tag="SLE23_001777"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8468679.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(14739..14957)
                     /locus_tag="SLE23_001778"
     CDS             complement(14739..14957)
                     /locus_tag="SLE23_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468680.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            15075..16691
                     /locus_tag="SLE23_001779"
     CDS             15075..16691
                     /locus_tag="SLE23_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEI8468681.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(16932..18272)
                     /locus_tag="SLE23_001780"
                     /pseudo
     CDS             complement(16932..18272)
                     /locus_tag="SLE23_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18548..18703)
                     /locus_tag="SLE23_001781"
     CDS             complement(18548..18703)
                     /locus_tag="SLE23_001781"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEI8468682.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(18999..19331)
                     /locus_tag="SLE23_001782"
     CDS             complement(18999..19331)
                     /locus_tag="SLE23_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8468683.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(19845..20036)
                     /locus_tag="SLE23_001783"
     CDS             complement(19845..20036)
                     /locus_tag="SLE23_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468684.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(20130..20516)
                     /locus_tag="SLE23_001784"
     CDS             complement(20130..20516)
                     /locus_tag="SLE23_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8468685.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            21210..22415
                     /locus_tag="SLE23_001785"
     CDS             21210..22415
                     /locus_tag="SLE23_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEI8468686.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            22432..22866
                     /locus_tag="SLE23_001786"
     CDS             22432..22866
                     /locus_tag="SLE23_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468687.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            23483..>25809
                     /gene="esp"
                     /locus_tag="SLE23_001787"
     CDS             23483..>25809
                     /gene="esp"
                     /locus_tag="SLE23_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HEI8468688.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         8895 a         3698 c         4832 g         8384 t
ORIGIN      
        1 ggaataatat gcttcaaaat tttattaatg gtctgtatga ctttcacttt ttacagaatg
       61 ctctaattac atctgtagtt atagggattg tttctggaac agtaggttgt tttattattt
      121 taagaggaat gtctcttatg ggtgatgcta tttctcatgc tgttttgcca ggagtagcaa
      181 tttcttatat tttaggtatt aattttttta ttggtgcgat tgtatttggt ctattagctt
      241 ctatcattat tacttttata aaaagcaata gtgtaataaa aggagataca gcaattggta
      301 ttactttcag ttctttttta gcattaggag ttatccttat aggagttgca aatagctcaa
      361 cggatttatt tcatatctta tttggaaata ttttagctgt acaagatatt gataagtgga
      421 ttacaattgg cgtttctgtt ttagtgttgg ttacagttgt tctatttttt aaagaattat
      481 taatcacttc ttttgatcca ttaatggcaa aagcaatggg gatgaatgtc agtttttatc
      541 attatctatt aatgattcta ttaactttag tagcagtaac agctatgcaa agtgtgggaa
      601 ctatattaat tgttgcaatg ttaattacac cagctgctac agcatattta tatgcaaaca
      661 gcttaaaaac tatgatattt atttcggcga cagtcggagc gtgctcatca ttgctaggtt
      721 tgttcattgg ttatagtttt aacatagcag caggatcaag tattgtttta acagcggcat
      781 tcttatttgt aattagtttt ctaatctcac caaaacaaaa atttttaaga aagaaggaga
      841 gaaagttatg atgagaaaat ggaaagcagt actgggaagt ctggggattt tgattgctct
      901 ttttatattc ggggcatgtt caacaaatag taaagacaaa gatacagtgg cttcgaacga
      961 aaaattaaag gtagtagtta ctaattcgat tttagcagat attactgaaa atatagcaaa
     1021 agataaaatt gatttacaca gtatcgtacc tattgggaaa gatccccacg aatatgaacc
     1081 tttgcctgaa gatgttcaaa aaacttcaaa agcagatttg attttttata acggtgttaa
     1141 cttggaaact ggaggaaatg cttggtttac aaaattagta aaaaatgcga acaaagagga
     1201 aaacaaagac tattttgcag caagtgatgg catagatgtt atttacttag agggtcagag
     1261 tgagaaaggg aaggaagatc cccatgcttg gttaaattta gaaaacggta ttatttacgc
     1321 taaaaatatt gaaaaacagt tagcggaaaa agatcctgat aataaaaaat tctataaaga
     1381 aaatctagat aagtatattg aaaaattgga ttctctagac aaagaagcta aatctaaatt
     1441 tgcttcaatt ccgaatgata aaaaaatgat tgttacaagt gaaggatgct ttaaatattt
     1501 ctcgaaagcg tataatgtgc cttctgctta catttgggaa atcaacactg aagaagaagg
     1561 aacaccagat caaataaaac acttagttga aaaattacgc acaacaaaag ttccctcctt
     1621 attcgtagaa agcagtgtgg acgatagacc aatgaaaaca gtatcaaaag ataccaatat
     1681 tcctatctat tcaacgattt ttactgattc aattgcagaa aaaggacaag atggtgatag
     1741 ttactatgcg atgatgaaat ggaacctgga taaaattgct gaaggccttt cgaaataatt
     1801 tggagggtag gtatggtaca aattaaaacg actactatac taatttattt actagcaatt
     1861 caggaattat caaaaagaaa aaagaaatta aaaaataatg atttagcaaa agttctaagt
     1921 gttagtccag catctgtaag tgagatgctg gctaaactta gatatgagga ctatttagat
     1981 ataggatttc aattaactga taaagggaaa aaatttattg acgattacaa aaaaggtttt
     2041 aagtaaaaga ctttattttt agggaggata agaaaatggc tattggagtg attatgatag
     2101 gacttaccct aatagctgga tataattttt ttaaatcttt ctcggattat tttagaaaag
     2161 gtgaatgatt tagatgagtc tattaattct tgtaggattg ctttttgtat cagttatttt
     2221 gctctttctc attagtttag ctctaaggaa tgagttcagt aatagacgtt aacgattgaa
     2281 acttcaagtc ctgtgtaaga taatatagtt aattcatctt attaggagga agtacccata
     2341 gaaaccagag attatattac aactcaccaa aaattaatag aaagtggact aagccatttt
     2401 gaaaaagaag gatttcagca aactaagata aggcaactgt gcttgaccgc aggcgtaact
     2461 acgggtgctt tttataaaca ttttacttct aaggaagcgt tatttgaaga aattattcag
     2521 ccgcatatta atgcgcttat taatatgtat aatgaagagt ttaccaaata cctcttaaac
     2581 ttagaaaata tagatataga gaaaagttgg agagagaact tcaatgaatt agatccattt
     2641 attaattata tttttgagaa taaacgtata ttcgatttgg ttttattcca atcagctgga
     2701 accaaatatc aagatattgt tgaaaaaatt acatcatttg tgacaaaaaa gacagtctgt
     2761 tgtctagata agttaaagac tatcggaatg atcaatcaaa atttagtctt taatgaagaa
     2821 gaaatccact tctacattta ctcattctac gctacattct atgatatatt gaagcatagc
     2881 tattcaaaag aaaagactat gctattaacc agaagattgt atcaattttc tgttcctggg
     2941 tggattgaat tactgagtta attaaaaaaa agcttgcatt gagaattgtt ctcagttatg
     3001 ctttttgata agatcgcact gttatctgaa taacggtgca tttttgtcag cttaagataa
     3061 cagtgcgatc ttattttttg gaggtgaaag agtgtcaaaa atcaatccgt taaccttgat
     3121 tactttaaat atttttttcc ggtcattatt tttttaggaa agggaaatat atttcaagtg
     3181 gggtgtttca ttattgctac agttttagta ttgatgtttc gtaaaataaa gacatgtatt
     3241 tatttcatct tgatttattc agttctgttt ttagtaatga aaattattga tgctatcaag
     3301 atagagtttt ttactatatt ttttgggaca tccttatata ttgtatttcg aatgttgccg
     3361 gtcgtaatga tctcatggtt gttggttagt gtctatacta gcaatgaatt attatcctct
     3421 ttagaaaaaa tacatttacc gaaaaaaata atgttaagta ttacagtagt gatcagattc
     3481 tttccgactt atcgttctga aataagaatg attaaagaat ctttaaaaat gagaaacatt
     3541 cgcttgtctt tttttcagcc tctgcaatat ttggaatttc tgttagttcc cgttcttata
     3601 cgtgcaacta tgattgctga agaaatgacc gctaatgcaa taacaaaggg gatagaatct
     3661 cctgtgaaaa gaagttctta ctataaaaca aacatgagct tattagacta tatcatcctg
     3721 ttttccgtta ctattttttt cttaagtatt ttgatttgag gtgaaagaat tgtttgaatt
     3781 taacaatgtt tctttttcat ataaggatgt taaggaacaa gcgcttgttg accttaattt
     3841 ttcaataaaa aaaggcagtc ttacattgat tactggttct tctgggagtg ggaaatccac
     3901 actattaaag ttaatgaatg gacttattcc aagactttat gacggaaaat tggttgggga
     3961 aattttattt gaaaataact cgctacaatc cttaacacaa gaaagtatat caaaaaatat
     4021 tggctacgta agtcaaaatc ctagaggaca attctttaca acaaatacaa cgagtgagtt
     4081 agtattttcg atggaaaact ttggatttac aaaagagcat atggataaaa gaatcaatga
     4141 attagctgaa ttattagatc tttcaaatat attagataaa aacatttttt cgctatcaag
     4201 tggtgaacgg cagaaaattt ctattggatg tagtttatcg ctaaactcta aattaattat
     4261 attggatgaa ccgtcttcaa atttggactt caaagcgact aagaaacttg ctgacttact
     4321 ttgtgattta aaaaataaag gatttactat tgttatagct gaacatcgtt tttactattt
     4381 gaaagaatta attgatcaag ttctatttgt taaaaataga actgtaaaaa ctacaactat
     4441 tcagttgtta aaaactgaaa acaataacgc attaaggaaa tttgacattt ttaatagttc
     4501 gattgaagtt ccctatatcg aaaaggtaag tgcagatgta ttaaaagttg aagaaattac
     4561 ttatgaaaat attctaaaag acataaattt tgatgtcaaa gttggagatg ttattggttt
     4621 ggtagggaaa aacggtgtgg ggaaaacaac cttactaaga atactcatga agattattcg
     4681 ccctaccaaa ggaaagataa tcgaaaataa aaaaaatttg tcatcgccgt ttttagtaat
     4741 gcaagaaatg gattaccaat ttttcacaga atcagtgagg agcgagttag ccctggggaa
     4801 tgaaatagtt agtaaagatc agcaagaaaa aattttaaaa aaaatggaac tttataaaat
     4861 gaaagatcaa ttaccgtttg atttatccgg tggagaaaaa caaagattat tggtttctat
     4921 agcttcattg tcaaaaacta atttatttct atttgatgaa cctacaagtg ggttggatta
     4981 tatcaatatg gaaaggattg ctgaccttat taaagactta aaagaaaagg gtgcagtagt
     5041 tatagccact catgatccgg aatttcttta taaaacatgc aatagaatta tttatttaaa
     5101 aaatggtgga ataaaaaaag atataaaact tagagtagaa gattcaactt tgatagaaca
     5161 gatttttaat gacataacga aatagaattg aggagaatat atatgaaaac aaaagattat
     5221 atttttattg gtttagctac agttatttcc ctagtaattt actttttttc aataatggtt
     5281 agtagtattg gtggggcgtt tggtcacagc atatccccag ggatttttgg attattatct
     5341 ggaatcatat ttgtttatat tagctataac taccctagaa aaggaatttt tactatttac
     5401 acaattgttt tattgttatt ttttacgtta atgggcgggg cgtacttacc ttggtttatc
     5461 agttcgatta gtatggcgat cttagctgat attattctat ctgtatttgg atatgatcga
     5521 gcaattcctc aagttgtgtc ttgggttcta atgcaactag gcagtgctgc cggacagtgg
     5581 attcccatat ggttctttac agatcgtttt cgtcaagact ggatagatag aggacaatct
     5641 gctgcaacaa tggatgcaat gatccactac gcggtgggta tatggggaat tatttcagtg
     5701 ttagttgtag caagtttatc tatgattggt gtattgattg gaagaaaagt cttaaaaaaa
     5761 tacaaaaaat agaacgtagt ttaccttcta tctgtttgta catctctaat ttacgctatt
     5821 acggaaagca ttaacagttg taaacgaata agagaagaaa ttgaatgcgg gggaggaaaa
     5881 aatgaaagta tacaaaaaat tatttagtta tgtccctaaa atgaaatact acggatggtt
     5941 agccacttta ttttctgatt tttctgtcgt attaacagtc tatggatatt acagtattta
     6001 caaatttctt cagtctctaa ttattgtagg agatgaatat ttagctaaga gttatgcggt
     6061 tcaaactgtt gcttggttaa ctttaggagc tttattttat attttttctg gcttattttc
     6121 tcatatcctt gggtttcgct tagagactaa tttgagaaaa aagggaatta gcggtttaac
     6181 agaagcaagt tttcgttttt ttgatttaaa ttcttcggga tatattcgaa agacaattga
     6241 tgacaacgcg gctaaaacac atatggcaat tgctcacttg attccagata gtgctcaagc
     6301 catagtaaca cctgttttat cagttgcctt aggctttttc attaacttta aaattggatt
     6361 ggttctaatc gccatgttag taattggtgt attcttgtta aagaaaatga cagagaatac
     6421 aaattttatt caaaaatatc aagaatcgtt agatgtgtta agctctgaaa cggtagaata
     6481 tatccgcgga attcaagtta taaagatatt tggtgctaaa gtaacatcat ttaaagcctt
     6541 gaataaagca attaacgatt atgctaagtt tgcatataag tattctttga gtgggaaaac
     6601 accttttgtt ctttttcaat ggctattttt tggcatagtt tgcattttga tagttcctat
     6661 aacctttttt ataacttctc ttaccactcc caagatctta gctgttgact tgttgatgtt
     6721 gtttttttta agtggaatta tttttgtttc tttcatgaga ataatgtatg taagtatgca
     6781 cttgtttgaa gcaagatatg cagtcgaaac actagactcc ctttatttag aaatgaagca
     6841 agaccaacta aaatatggga acgagacaca gattaaaaat tgtgacattg catttgaaaa
     6901 tgtcagcttt tcatacaaag aagagtgtgt tttagaaaat ttcaacttag ttttagaaca
     6961 aaaaagaatt tatgcattag taggaaaatc aggaagcgga aagagtacga tagctaaact
     7021 aatttcaggt ttctacaatg tggataaggg acagattaaa attggtggta agcctttaaa
     7081 tcactattca aaagacacaa ttattaacac aattgctttt gtctttcaag atacgaaact
     7141 attcaatcag agtatttacg ataacgtttc tatagcaaat cctcaagcgc cagcaagtaa
     7201 agtatttgac gcgctaagat tagccggttg cgaatcgatt ttagaaaaat ttcccgaaag
     7261 agagcatacc ttaattggta gtaaaggagt ttatctgtca ggaggagaaa aacaacgtat
     7321 agctattgcc agagcaattt taaaagatgc aaagattgtt attatggatg aagccagtgc
     7381 atctattgat ccagataatg agtatgaact acaaaaggct tttcaatatt tgatgaaaga
     7441 aaaaacagtt attatgatag ctcatcgatt atccagcatt aaatctgtag atgaaattct
     7501 tgtcttgtca gaaggaaaaa tagtagaacg tggaaatcat aatgaattaa tggctaaaca
     7561 tcgagtgtat aaacaattgg tcactaatta tgagaatgca aatgattgga ggcttgacaa
     7621 tgaaaaattt ttataaaaaa aaatttgctt taactgatca gggcgcagaa gctttaacta
     7681 aagcttctat ttctagtttt tttgtatact gcattaatat ggtaccagca ttcattataa
     7741 tgatgctgat agacgaatta gttttagaaa atgcaaagcc ccgttggctt tattttgcag
     7801 tatcgtttgt tactttgctt ttcatgtatt ggttgttaga tagggagtat gaaaacttat
     7861 ataatagtac ttataaagaa agtgcgcatt taagagtgca aattgcagac gatttgtcaa
     7921 atttaccatt atcctatttt tcaaaacata atttatcaga tttatctcaa actatcatgt
     7981 ctgacgttga aggtattgag catgcgatga gtcatgcaat acctaaagcc ggcggtatgg
     8041 ctctgttttt cccttttatt tcagtgatgc ttttggttgg taatgtcaaa atgggattag
     8101 ctgttatttt gccaacgtta tttagttttg tcttaatctt gttatcaaag aaatcccaaa
     8161 cgaaagccaa tactaaatat tacgatactt tgagagaaaa ctcggaagaa tttcaagaaa
     8221 ctattgaatt gcagcaagag attaatagct ttaatctatc taaaaaagtt caagacagac
     8281 ttttcaaaaa aatggaagag agtgaaagga ttcatttaaa ggtagaatta agtacttttt
     8341 cagtcatggc cttatcctct attttctcat atgttagttt agcagtagtc attctagtag
     8401 gtgttcactt actgttaacg ggtgaagtga ctatactcta cgtcgttggt tacttactag
     8461 ccgcaataaa aataaaggat tccttcgatt ctatgaaaga agcagtgctt gaaatatttt
     8521 atttagctcc taaaatacag cgaattagag ctatgaagga aaccagtatc caagagggat
     8581 cagatagtcc tctgaaatct tttgacattg agttgcgaga tgtctctttc tcatatgata
     8641 acaatacccc aattttagat catatctctt ttacggctaa acaaggagaa gtgactgcgt
     8701 tagtaggtgc tagtggttcc gggaaaacta gtatcttgaa attagtgtct agactgtatg
     8761 attatgatga aggctgtatt ttaattgatg ggtatgatat taaacgtgta tctccagctt
     8821 ctttgtttag caaaatcgct attgtttttc aagaggtaac tttgtttaat acaagtattt
     8881 tggaaaatat acgtattgga aatagtcaag cgtcagatga ggaagtgaaa aaagcagctc
     8941 gtttagctaa ctgcgaagac tttattgaaa aactacctga cggttatcat acattggtcg
     9001 gagaaaacgg aagttcactt tctggaggag agcgacaacg cctatccata gcacgggctt
     9061 ttttgaaaaa tgcgccaatt ttaattttag atgaaattac tgccagttta gatgcggaaa
     9121 atgaaaaacg tattcaggaa agtttaaatc gtttaataca agataagaca gtactaatta
     9181 tatcgcatcg cttgaagtct attgaaaagg taaataaaat tgtagtgatg gatcaaggaa
     9241 aactagttga tcaaggtact cataatgagt tgtatcgaag gtcagaaata tacaaaaatc
     9301 tcataaagaa aactaaacta tctgagaaat tcgtctatga aaaagaagct caatcacgat
     9361 gatgaaatag gctttaaatt aacctacaat ttttgggata tagttataat tctttttcaa
     9421 aaagaataat tttattaaac agcatctaat tttgaataca cgaaagaatc agtatgattg
     9481 aattagttca cttaatgtct attcttataa tataaggaat aatcaaagtt ttaaaaaatt
     9541 ggcgataaac cagttaaaca taaaagattg aataaaaagt tatagtttct ttcatattgc
     9601 cgttttaagt agaggaaaag ctacttaaaa cggtatttgt gtttgattgg actaataaaa
     9661 gtgaattctt atttttcaga gcctaaactg catattcttt taaatgattt gattatctct
     9721 atgtaccgat aaattcgttt tcaaatagtt atctattcat atgagtttta tttcatgtta
     9781 tttattgttg acaagagcaa ctcttgttgg taaagtatca gtgtcaaaac gtaacgatta
     9841 cgatttgagg tgtctaaatc aaaataaaag gagtataaag gtatatggca aaaaagtcga
     9901 aaattgctaa agcaaagaaa caaatggcga tgattgaaaa gtatgcagat aaacgtcagg
     9961 aattaaaagc cgcaggagat cgcaccgctc tcgctaaatt gccaagagat tcaaatccga
    10021 atcgtctgag gcttcgtgat cagacggatg gtcgtccaag agggtatatg cgaaagttcg
    10081 gtatgtcccg tattaagttt agagaacttg cccatcaagg gttgattcct ggagtaaaaa
    10141 aagcaagttg gtaaaaggag gaaatatcat ggcagtacca gcaagaaaaa catctaaggc
    10201 gaagaaacgg ttaagaagaa ctcatcaaac tgtagtaaaa ccagaaattt catttgacga
    10261 agcgaatggt gattatagac gtagccatca tgtatcttta aaagggtact ataatggaaa
    10321 gaaagtaatt aaaggagctt caaaatagtt taatatataa cttttaggag ggaatcaaaa
    10381 tggaaattat ttacccacct ttagttgaag aaggattaaa gtattatctt gaaacgaccc
    10441 agcaatcgct agataaatgc actttttatc gttcgatggt agagagagga attattactg
    10501 aaacgggttt accgacccaa caggcaattg aaaatggatt agtcaaagat tactatgagg
    10561 accaaggctt atcatttgat gattttttaa gaatctatcc aatttttgaa gagtatgacg
    10621 aggagttatt tcaatgtatc gatggttatt gggagatacc tgttgatatg aaagaaaatt
    10681 tagtttcaca attggaatct ggcgagttaa cttttgaaga tgcacaacaa attcaagcat
    10741 atcttgaaga tcgataagta ttgaaggagg aagatttatg cgtcaaaata ttattttgga
    10801 atgtgtcgaa actggagaac gtctgtatct caccagcaaa aataaacgga ataaccctga
    10861 acggttagaa ttaaaaaagt attcgccaaa attgcgcaga cgggcaattt ttaaagaagt
    10921 gaaatagcta agtggtaaaa aggtgacaaa atgggcatac cagttacaat cgtttctggg
    10981 tttttagggg ctggaaaaac aacgctaatc aatcaagcct tgcaagtctc accctacccc
    11041 agggaagaaa ttattataat tgaaaatgag tttggtgaag ttgggattga tcacaaatta
    11101 ttagttcata gcgaggaacg ggtgttacaa ctaaataatg gatgtatgtg ttgcagtctt
    11161 cgcagtgatt tattagcaat attgatttct ttactggaaa caatagaaga acatcaacaa
    11221 ccaatttcac aaatcatcat tgaaactaca ggtatagcag atccccaacc aatcattcaa
    11281 acacttttaa cagcgcctca actaagagga agagtatata tcgatagttt attgactgtt
    11341 attgatagtg acagttttga acttattgaa agagaaccac aagcccttaa gcaacttgtc
    11401 atggcagatc gcatttttgt gtctagaaaa caaaacttga atttatctgc actaaaaaaa
    11461 ttacagagag aaatcaaaag tattaaccct ttatccgata ttcgaatgtt cacacatagt
    11521 gaaacgattc aaaaaaagga tttttataat ttgaaaaaat ttaatcatcc cttagttttt
    11581 gaaagtgatt catcagaaaa tcactataat ggcaaatact atcatcaaca ccatcaagta
    11641 catgagttta aatcaattct cttaacttca gatcaagaca taaaaaaaga ttttttactc
    11701 caatggattg actggctgat tttaaccaac caagggagcc tgtatcgttt taaaggattg
    11761 attgctttac aagagcagga ttttatagtt gccatgcaag aggtaaacga acaggttaat
    11821 tttcaataca ccactcgaca aaaagaccaa accactatta ttctaatcgg aaaaatgttg
    11881 gatgaagaaa ggatcaaaca gagttttgat aaattactgg cggaaagcaa ataatgataa
    11941 gtagtgattg ggggtaattt ctaatggaga aaacggatat atctagtgca tatcgacgac
    12001 ttaaaagccc gaatattaaa actagaaaaa gggcattaaa aattatcaaa gaacataaac
    12061 gaaataaaat gaagaaatta gcataattaa ggaaggaaaa agaatgaaga aaatcagtgt
    12121 aggacttatt gggatagcag ctctaggatt attgggagct tgctccagca ctaatgatgc
    12181 aaaagtatcg aatgataaag atggaaaatt agaaattgta acaacattct atccaatgta
    12241 tgatttcacc aaaaacatcg tcggcgatga agcgaacgtg gatttaatgg ttccagcggg
    12301 atcagaacct catgactatg agccctcagc taaggatatg gcaaaagctc atgatgctga
    12361 tgtttttgta tatcataacg aaaacatgga atcatgggta ccaaaagcta aagaaagttg
    12421 gaagaaagct gggcctaatg tagtagaagg aacaaaagac atgattttat tgccaggtag
    12481 tgaagaagaa gatcatgatc acggagaaga agatcaccat catgaactag atcctcatac
    12541 gtgggtttca cccaaaatgg caattaagga agtttcaaat atcaaggatc agttagttaa
    12601 attgtatccg aaaaaagcaa aagtatttga gacaaatgct gaaaagtatt tgactaaact
    12661 gaaacggttg gatgctgact ataccactag tcttaaagaa gcgaaacaaa aaagttttgt
    12721 gacgcaacac gcagcctttg gatatttagc tttggattat ggattgaaac aagttcctat
    12781 tgctggacta agtcctgaag aagagccatc ttctggtcga ttagctgaat taaaagagta
    12841 tgttaaaaaa aataagatca attatattta ctttgaaaag aatgctaatg ataaaattgc
    12901 aaaaactttg gccaacgaag ctgggataaa attggaagta ctgaatcctc ttgaaagtct
    12961 tacaaaagaa caaatggata atggtgaaga ttatgtttca gtaatggaag acaatctaaa
    13021 agcgttagaa aaaacaacta tggttgctgg tgaagaggta gttccagaaa aagaagcgaa
    13081 ggatgaaaag acagttgcta atgggtactt taaagatgcc gatgtgaagg atcgcgaatt
    13141 gagtgattat acaggcgaat ggcaatctgt ttatccgttg ttaaaagatg gaattttgga
    13201 tgaagttttc gattacaaag caaaaatcaa taaagacatg acagctgccg agtacaaaga
    13261 ttattatact actggctata agacagatat tgatactatc aacattaaag acaacaccat
    13321 tgattttgta gtcaacggtg aacatcatca atacacatac aaatatgttg gatacaaaat
    13381 tttgaattat gaaaaaggaa accgtggtgt tcgttttaat tttgaaactg atgatgcagg
    13441 tgctggtcgt tttaaatata ttcaatttag tgatcatgga attgcaccaa gtaaggcaga
    13501 gcatttccat attttctttg gtggagaaag tcaagaaaaa ctctataatg aattgcataa
    13561 ttggcctact ttctatccag cttcattgtc taaacatgaa attgctcaag aaatgatggc
    13621 tcattaaaat tcaatttttg gaggaaatac atggtaagaa aagtattatt gtctatggat
    13681 tccaagaata ttgatgctta tcggcgttat cgatttgcaa agcaaatgag attaaatggg
    13741 agtacattag ctgatattgc tgcaacttta catgttagta ttgacacagt tcatagagta
    13801 ttaaaacggg atcctgattg ttgttttatc aaggtcaata ctggaagaag tagacgttta
    13861 gcaaaacggc ataatagctt ggccaattaa ttgataatac cagagtagat catttttccc
    13921 ttatttggat ttgatctgct ttttattatg tcttgaattg tcaaatcaag cgcaacactt
    13981 tatcaaagaa gacttcataa ggtgttctcc aatctaaaca ctttctaggt ctgttattca
    14041 gtttttcaat catctgattt atcgttgagt tatctaccgt agctatctct ttcgattttg
    14101 gcaagtattc tcgaatgagt ctattcgtat tttaatttgt tcattgttgc caagggcatg
    14161 aggatctgga aaataaaagg gcatattatt caatgcttct gtaactgcga aatgattgga
    14221 gaattctttt cctctatctg gagtgatcgt tttgaccgcc tcatttggaa tactgcttaa
    14281 aagttcaatc attttctcgc tcacataagc ggctttcttt ctggggacct tctttcctgc
    14341 taaaaggaag catgattttc tgtctgtcaa agtcactaaa caagtaccac cagttttgcc
    14401 agctacaata tcggctttcc aatgaccaaa atcacttcta tcatctgcgg attttggacg
    14461 gccatggatc gaatgagtaa ggcaaatctt tccacgagac tcgacatgat tttttgtatg
    14521 tcttgttttt cctcgatggt gcaatgaacg gatcaggcct ttattgccgt gtgagagggg
    14581 ttctgtatcg aaaagatcat tgcaaattgc acgttagatc gtgataaaac taattgaaaa
    14641 gtccatatgt tcatgcttca aacgattcga gatttcctct ggcgaccact gaaaatcgac
    14701 aaataaatga cgaacaattg accaaactca cggatcattt agaatgtgat aacgtccgca
    14761 tttttttctt cgataagcat aatttttttc cgctttggaa ggtgaatagt ttttttcttg
    14821 tttcttctca gttcatgtaa aatagtaaac gggctatgct gaatgtcgtt gccaattata
    14881 ctaatagaaa atccttcttc gtgaagcaga aagattcttt ctcgttcgag tatagtaaga
    14941 tgacgatact ggctcataat tattttcctt ctaggagtgt tctcgacaaa cttatactag
    15001 ttggatatcg attatgactc atttttatgt gttgcactta aagtgtaaat tcaaggtata
    15061 gaaagaggtt ccctatgaaa aaaataccta ttacaatctt aactggctat cttggttcag
    15121 gaaaaacgat acttctaaat catattctgt acggtgatca cggaaaggaa attgctgtca
    15181 ttgtaaatga cataggggaa gtaaatgttg atggggtatt agtcgacaag aaaggtttta
    15241 aaagaactgg agaaaaactt gtttcgatgc cgaatggatg catttgttgt acattacgcg
    15301 aagatttgat tgttgaacta gatcaattag tgcaattttc tgacttgaat caaattgtta
    15361 ttgaagcttc aggaatcagc aaaccaattc caattattca agcaattata ttagctaaaa
    15421 accctttaga cattgatttg acccaacgat tagagattgg tgccattatt atagtagtgg
    15481 atgtaaaacg tttttgggat aatttcgaaa cgggtgaaaa gattcaggaa agaaaagctg
    15541 aaggtaatgt agttgaagaa gaacaggata ttcgtggctt gttaattgat caattcgagt
    15601 gttgtaacat attactttta aataatagtg acttagtgtc aaccaagacg atttacaaaa
    15661 ttaacggtct aattgctaag ttacagtcca atgccaaaat aattaggaca attaaaggtg
    15721 aagtagactt atcgaaaatt ctaaatacaa atctttttaa tatagatgag acttcctatt
    15781 cagtgggctg gttcaaagag ttagagcttg gctatcaaaa tcatattcct gaaacagaag
    15841 aatatggtat ctcaagtttt atctatcgaa atcggttact ccttgacgca caaaaatttg
    15901 cccatcttac ggataaaaat tttcctggca atattacaag agcaaaaggg tttctttggt
    15961 ttgcccaaca tagtgatttt tcgacgatct ttgaaacatc gggtagctat aaaagtattg
    16021 aatcattaaa ttattgggta gctagtttac ctaaaattga gtgtcaaatg attatacaaa
    16081 aaaatcccga attgaaggaa gcctggcatc cgttgtttgg tgaacgcatt aataaactag
    16141 tttttattgg tatgaagatg gatcaacaat gtattaagga acaacttgag ggttgtttaa
    16201 ctgattctct taatgcagat aatttccgaa aaatttcacc atttccatgg aaaaagtcta
    16261 atatgtttag ccagatatcg ttaatgaaat ttttaagaaa agctggtgtc aagataggcg
    16321 atgtcataat tattggcatt ttgattatta cctcttttat tcccttattt gtattctcta
    16381 tagaaaagga gaatgaaaca actgaagatg ctatcaaata tgccatcgtt cgaattgatg
    16441 gcaaggaaat ggatcgcttc gatttggata agatcaatca taaactcgtg aattatcatc
    16501 ctgcgaaggg acaatataat attgttgaga ttaaagatgg aagaattcga gttaaagaag
    16561 ataatagtcc tgatcaaatc gcggttagaa ctggatggat ctcaaaaccc ggtcaaacga
    16621 gtatttgttt accccataag ttagttatta gtattgagaa aaaagaaagc acagattact
    16681 acatttacta atctggaaat agatgaggag gtttttaata agaaaaagat attattatta
    16741 ataatagcag gggctttatt aagtgtgtta agcgcttgtg gacaagaaaa agaagcggtg
    16801 acaacaggca caagtatctt taacgggacc tgcaatggtt tagttaacag tcggttagat
    16861 tacttatttt ggctcttcgt caatgagtgt tggtgaagaa attcaataga ataatcgaga
    16921 tactcacacg gctagacagc tatcttgtct agccgtgttg ttgttctggc tttagtcagt
    16981 tgggtagtat tcttagtttt cttaaaatat tttcctcgat ataaaaagat tcgttctcgg
    17041 tagttttgaa agtttctata gccataggca attcgtttta gtactttgat atggttattc
    17101 aaacattcta tagggccgtt ggaataggga acgcgcaacg ctcgtttgat ttctgtttgg
    17161 tatttcttga aggtcgtgaa cactggttgg tagtgctctg gcaactcctt gtagtcttct
    17221 tttaggagcg cgacgaattc aggaacatct tgtcttctga taacggaaag aaaatcctgg
    17281 tagacttcgt agcctcgctt taaggaatca tcataagata atagccgatc gactatctct
    17341 gcttctgtca gatgatctcg aaatgacgga cgccagtagc gatgctgacc tttcaattcc
    17401 cacgcattct tttgaagtag tttccagtat ttctttaagt gcttcgaccg acgatcccct
    17461 tttttaaagg tcttcattac ttgaattcgg tggttggtaa aagcccgacc aatgtgttgg
    17521 ctaatatgaa agcgatcggc gacgattcgg gcattcggaa aacactcttt caccaatgtg
    17581 cgatagggtg tatagaaatc tgaaaccact agacgcactt gttcacggac ttttataggg
    17641 tagcgcaaga aatagtcgcg taaaggattg agttgccgat tttccacaat atcaatcagt
    17701 tgatgggtct tgccgtccat catgacaaag ctcatggctc ccgagacatt tttcactgat
    17761 ttgaattcat cgaaacacac cacttctggt aacagctggc tcaaagaaat ggttttaggc
    17821 cgaaggctgc gaagtattcg aatgacagtg gtcggagaaa tgtgcttcat acgtgcgatc
    17881 aaagacatag aaagaggttc gcttaatagc tcaagaatgg cttgtttgac tctgcgagca
    17941 atggagcagc gacgatcact aactgaatct tctgctaaaa aagtctttcc acagtgttta
    18001 catttgaagc gctgtttgtt aatccgcaga atggtcttgt agttactgac atcattcaat
    18061 aagatggata cttttttcca gccctattta atgatcgttt gttcattttg atagtggcga
    18121 tgaaagcatt cctccggttg ataggtcaat gtgccatcaa aagcaaaaca tgtttcgtca
    18181 ttgatgcgct ctttgcgaaa ggcatcctca tgaaaggtaa gatttaggtc tagaatatct
    18241 agtaactctt tggtaaactc tgaataggac atcttgaaac actactttga atggtttttg
    18301 tcgactttat tctaaaggat tttaaggtgt ctgtttgcgt ttattagaaa aaagaaaaag
    18361 tattggcaac agaaggcgtc accaacacta gatattatag atcccttatt ttcttcgctt
    18421 caaattgtca aggagtcatc ataaattttg tatggattct tttgtttggg tagtagtctt
    18481 ctaaataatc ttggattaac accttcatct ctattttact tttatatttg ttggagtcga
    18541 ttaattctca tttgattgat cgatgaaacg cttcaattac tgcattgtca acaggagtcc
    18601 cagtttggct cactgaatgt gtgatgtggt ggtcgttcaa cagctcttga taaataaaag
    18661 accgatgctg gctacctcta tcggaatgaa ttaccgtagg caattctcct taataaattt
    18721 gtaatggacg gacgacaatc tcttttttta tgtgtgaatc taccatatag taacgtagaa
    18781 tacgagttgc taagtcaata taggtggaca aatagaggcg accgtcatta catggaatgt
    18841 aagtaatatc catcacccaa acagcatcaa tttggttctg ttcaaattat cgattcaaca
    18901 tttttttacc atttctttga ttgttttttc tctaccatga gaagatttgc gtcgatgaaa
    18961 tcctcttgtg cataaattca tttcacgcat aagaacagct acaacacgtt tattgatttc
    19021 gattccttca tcgtaaagtt tttgagtgat ccctggagat ccgtatcgat ctttgtgttc
    19081 gtagaacact cgtcttcctc ttttagtcgt ttattttcct gttcaagaat gtagaaatct
    19141 gctttatcag gtaatctttt tccttgtcca gcaaaagcat ttttcccgta tcgacgatat
    19201 tctgaaaccc atcgggaaat tgttggacga gagatattgt attcttcagc aattttcttg
    19261 gtagttactt ttttctcaag gatatcctgt gaaatcttta gtttaaattt acgatcatat
    19321 gtttttctca atagagttca ttccttccgg taacgtaact gatagtcaag aaaagtgtat
    19381 catagcccaa cttagtatca gggtttgtca actaaactgt ggaagttgat agataagagt
    19441 ttttaacaac caaaattctc ttgactattt ttgaaatcag acaaattttg attggacaca
    19501 tagttgaata aatctaccgt cgttacggaa ggtaaatcgc atgcttttca attctagagg
    19561 agaagtcctc gttgaagtac catagcccag ttctggattc gacctcctgc ccacttcata
    19621 cgtaaataaa gtaattttag gagtgagact gtgacaaaag ttatttttaa gctaaaaacg
    19681 aattaaaaaa cgttgataat taaaatcatt cgttttagat tctatgaatc attatagaac
    19741 gctgtaaaat cgatacttta taattataaa gaagatagtt tcaaatttat tgttcgaaat
    19801 ttgaaactat ctttttactt atgtcacaga ctcccttagt tgagttattc tttaatttcg
    19861 aatttcgaga tagctagata tattgcaagc atacattctt gataacaatc ttgatcatat
    19921 tttccagttc tccaggattg cttatgaatc aaagagctaa atcttttgag aattgcctca
    19981 acagcttctt catttccagc ctttgctaaa atgaaatctt cttttaaaga attcataaat
    20041 ctaccttctt cccatggact tataatctat ttctttggga aggaggagaa cgagcaaaga
    20101 agcatacaaa attagttatt atgcagatat taaaccagca ttttttgaat ttttttgtaa
    20161 agtcgatgtt ttaaatttgt cgcaccctgt cttgtaatcc ccagaacctt tccaatttct
    20221 ttatcagttt tatcaaagat aaatttttcg ataagaaaaa tttgttcagg ttctttcaac
    20281 aaaggaagga tttttgctaa ttttatatct tcaacaagga gagtcacatt taaaacatta
    20341 atcggttgtt taaattttat agtatcttta gtaaacaaat atggtgggag ttgatcaagt
    20401 tgttcatgtt tttgaatttc ttcttgtttt ttataataag tattagcggt gttcaaaatg
    20461 accttttcaa agaatcgaat caactgggca tttacgcgtt cgtcgttatc tgacatattg
    20521 cacacctcct ccattaagat ttaaagggaa aagaggcaaa aaacacgaaa agaagctaat
    20581 gcaattatgc tgcgctgcga ataacttcta taagctcaca tgcattgata ggactgctga
    20641 tgtttatttt caaaaatgtt tttttagttg ataatggata gttatcttta tacttagaaa
    20701 agaaaattca tatatcttct taaatatcaa acatgtcctt atggctaaga aaatgtcttg
    20761 agctttttac gtataataaa tcttttctaa aacctccttt tggataatat tcttattcgt
    20821 gtatagattg tattttttat ttcttccccc ttcataatta acaactagaa aagagttcga
    20881 atagacacgt atttgaacga aaatttttat tggattccca aattggaata tttagaaacg
    20941 aaaaattcct attatctgta tagtgcttag ataataacgg atcataataa ttattgtctt
    21001 tgaactagat atatgtaaat agtattcatc atgatgaaaa atgatgagtt ctcggtgata
    21061 aaatgtactt tttacggtgg aatatacatg aaagcgataa gtggatattt tataatgaag
    21121 taagttagct tattttgaca gaggaatagt attttagata acgtataaaa tactatttaa
    21181 tgatgtagaa aggaaagaga gaaacaaaag tgttttcaga taaagaagtc ttattaaagt
    21241 ctcttcatgt ttgtttaaag ttacctatcg tggtttttaa ttccgaattc agtattataa
    21301 aagagtatcg ctcagataga actacttatt ttttttatga ttataaaaag ttactaactg
    21361 ataatattaa aaaaactaaa gatttccatt tctttactgg tgattttaat gagatgtttc
    21421 ttctatacat gtttaaaacc agatattact tatttggtcc atttagagca aataatattg
    21481 ataaagtttt ttttaaacta aaaatgaaca atttgaatgt tgcaatggct gatagagaac
    21541 gactctataa ttcattgcaa aatttgactt tgtattcttt aggagacatt cgagatattc
    21601 tgattttagt tcattatttt tttactggaa aaatagaaga tctattccat gaaccgttaa
    21661 ttgaatatac agaaaatcta agtaaaacta tcgagcaaat caaaatagat aatctgttat
    21721 cacaaaatta cgatccagaa atatatctgt ttctttatga aaataaaata ctggaatatg
    21781 ttaaaaatgg agatattcga aatttagaaa acatggtttt taatctgagt aatggaataa
    21841 ttccaagtgt tagtggagat acgattcggt ctgaaaaaaa ttattctatc attgtttttg
    21901 aaaagttagc acaaacgtct ataacattag gaatggatat aatagaagcg tatcaaagta
    21961 gagatgcttt gatacaagaa aacgaattag ctgtatcgtt acctgaggtc ttaaaagtga
    22021 gggattctgg gattgtttat tatactaagg aaatcggaaa aactaagata gagcatcttt
    22081 ctcccttaat ttcttctgtc gttcaattca tcggcttaaa tatctataaa agaattactg
    22141 taaaggaaat agctaattat ttttctgtaa gtgaaactaa attaagagaa agctttaaga
    22201 atgaaatgca tattacgatt tataattata tctctaagcg aaaaatttct acggctaaaa
    22261 taatgttgaa atcaaaccat actatcagtg aagtttcttt aggtttagga ttttcagatt
    22321 cttcacactt ttcgagagta ttcaaaaagt acgcaggtgt atctcctaag caatatcaat
    22381 taggtttagt ggacaatttc aacaacatta gctgagaggt tttattttat tatgagacta
    22441 tatcatttac gtagtttgga ggagttgagg aaattggatt ttaacaaaaa atttttttgg
    22501 gaaatttctg atttgagttg tttcgtagaa tctgagcgtc taagtaatgg taataatagt
    22561 gtgttaaatg aatatgacaa agtagtaatt aataaagtaa aaagtttatg tgaagaagct
    22621 agagaatcta tcagtcatat taatggtagc aattttaaac aaacattatt taatctgatt
    22681 aagctagatg ctaaaatatc aagttattta ttctttttga tacatgatga atttatggat
    22741 tatcaaaaat tggatcagtt aattgaaaga gaaagctggg aagattatta cgtgggtcta
    22801 actttttcag aaaagttaaa caactacaag ttaatagatt ataagtattt gagtgaaagc
    22861 aattaattat tcatgtagag tactagacac tttaaatatg gacaattcaa ttataaagaa
    22921 aaagaatcaa taatttaatg aggctgtgac aaatgtcatt ttttgtttcg ctaaaaacga
    22981 gtgaaaaaat gttgataact ccaatcattc gtttaagatt ctaggaatca ttcagaaatg
    23041 ctgtgaaacc gatactttat aattataaag aaggtgattt caaattccga agaaggaatt
    23101 tgaagtcacc tttttactta tgtcacagtc tcattcagta atgcgggata aggctcctta
    23161 ttccgttatt tgaatactct gaagtttaat ctaagaaagg gtaatatttt gaaaacatgc
    23221 ttcatcgcat agaaatgaac ttaatttcag aaagaataca tacatatctt tttatatgtt
    23281 ttcagctgct gaatggttaa aaagcacaaa tatccgaaaa aaacatgaag aaatgtactt
    23341 tttttgttgt aatgttcatg aaattctcta agtaaattag ttaacataag gttagtaaga
    23401 ttcctattct gtgaataata cgtatcagat ttatctttta ttcttactag gaaagtaatt
    23461 attaagggag ttgatttgaa taatggttag caagaataat aagagagtat ttctagaaaa
    23521 aacaaagaaa cgagtattga agtacagtat caaaaaatta agtgttgggg ttgcatctgt
    23581 tttgattggt gttggtcttg tcttgggaac aactgaacta gttaaagcac aagatgaaat
    23641 ttctccaagc agcccacttg aaacagcgat aagctccgta caagtaggtg acaaagtagc
    23701 ttcggggaat acttttcagg agaatcctgg ttatacgaaa aattataact tttcggattt
    23761 acaatttagt cctcaagaac taactggaga cacactaaaa ggcaatacaa ttggatttga
    23821 agtttacgga aaacataata ttgcagcatc aactaaaaac tgggaaatcc gtcttcaatt
    23881 agatgaacga ttagctaaat atgtagaaaa aattcaggtc gatccaaaga aaggaattgg
    23941 atcttctaga cggacctttg taagaattaa tgattcgctg ggtagaccta caaatatttg
    24001 gaaggtcaat tatattcgtg caagtgatgg attatttgct ggggcagaaa caaccgatac
    24061 gcaaaccgct cctaatgggg taattacgtt tgaaaagagc ctagatgaaa tttttaaaga
    24121 gataggcata gacaatctca agaccgatcg tttaatgtat cgaatctact tggtaagtca
    24181 tcaagacgat gataaaattg taccgggtat tgatagtacg ggctactttt taacagattc
    24241 agatgatttc tataatagct tagatgtatc tgaaaataat cctgaccagt ttaaacatgg
    24301 atcagtaagt gcaaaatatg agaaacctaa tactcaaaca aaagatggtt caggatccac
    24361 aggtgctaat ggagctataa tcttagatca taagttaacg aaaaattata atttctcata
    24421 ttcatcttcc gcaaagggca cgccttggta tgctaattac aaaattgatg aacgattagt
    24481 tccatatgta gcgggtatac agatgcacat ggttcaggct gacaaagtaa catatgatgt
    24541 ttcgtttgaa tccggaacaa aagtagctga tttagcaatc gagcgacggg aaggtcatga
    24601 aaattatggc ataggttcaa taactaataa tgatttaact aaacttatcg attttgctaa
    24661 tgcaagtcca cgtccagtcg ttattcgata tgttttacaa ttgactaagc cattagatga
    24721 aatcttagaa gatatgaaag caacagcaca agttgaagaa aataaaccat ttggtgaaga
    24781 tttcatcttt gattcttggt tgtcggatac gaataaaaaa ttaatccaga acacttatgg
    24841 aacaggttat tattatttgc aagatattga tggtgatgga aaccctgacg ataaagaaga
    24901 gagcggagac acgaatccat atatcgggaa acctgaatta gaagaagtat atgatgttga
    24961 cacaacagtt aaggggaaag tattcatcca cgagttagcg ggaacaggtc acaaagccca
    25021 acttgttgat aaagaaggta ctgtattagc agaaaaaact atcgctccaa atgaaaaaga
    25081 tggggctcca atttcagata ctgtagaatt tgaatttacg ggtgtagatt caagtaaatt
    25141 aatcgcgaaa gatgaattaa aaatccaaat cgtttctcca ggttttgata aaccagaaga
    25201 aggttcaacc gttattaagg aatcaccaaa agcggttgat aaacaaaccg tggtagttgg
    25261 atttaaacca gatgctaaag aatcaattcg gaataataaa aacttacctg aagatgcaga
    25321 gtattcatgg aaaacagagc ctgatacttc taacgttact gatagtacga aaggtattgt
    25381 aactgttaag atcggaaatc gaactttcga cgtggatgta gagtttgctg taaaagcttc
    25441 tcaagctatg gaaaatgatg caacatacgt acctataaca acaactccag aaacgacagt
    25501 tcaaagtgga aaacctacat ttgataaacc agatgttcct ttagctaaag atgccttttc
    25561 aatttcagat gtctataata aggacttcgg taatgcaagt gttgatgcaa acactggtat
    25621 tgttacattc actccagcta aaggtgtagg agaatcggag ccgattactg gaacaattcc
    25681 tattaaaatt gtttaccaag atggttctgt aggcacgacc gatttagcag taactgtaag
    25741 taaagatatt tatgaaaatc caggagaaaa cattcctgca ggctaccaca aagtaacctt
    25801 caccgcagg
//
LOCUS       DARPZJ010000036        24470 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.037, whole genome shotgun sequence.
ACCESSION   DARPZJ010000036 DARPZJ010000000
VERSION     DARPZJ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.037"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            119..766
                     /locus_tag="SLE23_001788"
     CDS             119..766
                     /locus_tag="SLE23_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEI8468689.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            850..1794
                     /locus_tag="SLE23_001789"
     CDS             850..1794
                     /locus_tag="SLE23_001789"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEI8468690.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1929..3380
                     /locus_tag="SLE23_001790"
     CDS             1929..3380
                     /locus_tag="SLE23_001790"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEI8468691.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3401..4237
                     /locus_tag="SLE23_001791"
     CDS             3401..4237
                     /locus_tag="SLE23_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEI8468692.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4237..4896
                     /locus_tag="SLE23_001792"
     CDS             4237..4896
                     /locus_tag="SLE23_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEI8468693.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5022..5711
                     /locus_tag="SLE23_001793"
     CDS             5022..5711
                     /locus_tag="SLE23_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468694.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5717..6673
                     /locus_tag="SLE23_001794"
     CDS             5717..6673
                     /locus_tag="SLE23_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HEI8468695.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6717..7229
                     /locus_tag="SLE23_001795"
     CDS             6717..7229
                     /locus_tag="SLE23_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8468696.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7485..8033)
                     /locus_tag="SLE23_001796"
     CDS             complement(7485..8033)
                     /locus_tag="SLE23_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8468697.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8122..9303)
                     /locus_tag="SLE23_001797"
     CDS             complement(8122..9303)
                     /locus_tag="SLE23_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEI8468698.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9539..11047)
                     /locus_tag="SLE23_001798"
     CDS             complement(9539..11047)
                     /locus_tag="SLE23_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEI8468699.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11206..11397
                     /locus_tag="SLE23_001799"
     CDS             11206..11397
                     /locus_tag="SLE23_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468700.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11600..12517
                     /locus_tag="SLE23_001800"
     CDS             11600..12517
                     /locus_tag="SLE23_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HEI8468701.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12510..13583
                     /locus_tag="SLE23_001801"
     CDS             12510..13583
                     /locus_tag="SLE23_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468702.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13731..14249
                     /locus_tag="SLE23_001802"
     CDS             13731..14249
                     /locus_tag="SLE23_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468703.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14230..14622
                     /locus_tag="SLE23_001803"
     CDS             14230..14622
                     /locus_tag="SLE23_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEI8468704.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14698..15633
                     /locus_tag="SLE23_001804"
     CDS             14698..15633
                     /locus_tag="SLE23_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEI8468705.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15766..16545
                     /locus_tag="SLE23_001805"
     CDS             15766..16545
                     /locus_tag="SLE23_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEI8468706.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16538..16855
                     /locus_tag="SLE23_001806"
     CDS             16538..16855
                     /locus_tag="SLE23_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEI8468707.1"
                     /translation="MTKLYLLLLVVCLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17099..18709
                     /locus_tag="SLE23_001807"
     CDS             17099..18709
                     /locus_tag="SLE23_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8468708.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18866..19714
                     /locus_tag="SLE23_001808"
     CDS             18866..19714
                     /locus_tag="SLE23_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8468709.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19945..20424
                     /locus_tag="SLE23_001809"
     CDS             19945..20424
                     /locus_tag="SLE23_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468710.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20457..22685
                     /locus_tag="SLE23_001810"
     CDS             20457..22685
                     /locus_tag="SLE23_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8468711.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22814..24457
                     /locus_tag="SLE23_001811"
     CDS             22814..24457
                     /locus_tag="SLE23_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEI8468712.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKINK"
BASE COUNT         8074 a         4347 c         4960 g         7089 t
ORIGIN      
        1 tttttcttta tattttcata ataaaagttt ggttctttaa tttttaaaca tgacagaaaa
       61 ttttttcttc gttatacttg taatagaata ctattttata acaaagggga tcgaatcaat
      121 gaaaaaaact gttatttata ctagtttatt tgcagctttg tttttagctg cttgtcaatc
      181 aaataccaat caaggcacat ctgggaatac gtcttccagt agcgaacagc gctcttcaca
      241 ggtatcggac tcctcaacaa aagcaagcac atcttcgtct agccagacaa aaagttctag
      301 tgaagcaagt actcagtcag atatcaaagt gtctgcagct cgtgcgatcg aattgttcca
      361 agataaatac ccagatactg caattactag tttggaatta gatagtgatt ggggatctta
      421 cttctacaag atagaaggtg tcgatgatca aaaagaatac gaagcaagaa ttgatgctca
      481 aaatgaaaaa atggagacag agaatccaga aactctagat cgagatgaac aaaatggtca
      541 aaagaaaaaa gaagatggtc tggatgttga taaattgatc acgattgagg aagcagcaaa
      601 aatcgccgtc gacaaagtag gaagcggtac ggcaacagat tgggatttgg ataaagattt
      661 aggtactact tattgggaag tcaaagtaaa agacggcaat caaagtacat cagtcaagat
      721 caatagccaa acaggcgaag tactgtcaac tgaacaagat gattaagaat ttcttcggaa
      781 aacaagagtt gatttttctt ttagtcatga tacactagac aaaataactt gtttgaagga
      841 gcgatttact tgagtttaga aacgaccttt gccaatcata tctttgccaa tcctttgatg
      901 aatgcatctg gtgtccactg catgactacc caggaattag atgaactggc tcattcagaa
      961 gcaggagcat ttatcactaa gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca
     1021 cgctattttg atgttccttt agggagtatc aattctatgg gacttccaaa cttaggtttt
     1081 tcttattatc tagagtatgc tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg
     1141 ttattttttt ccattgccgg gatgagtgtc caggaaaact tggaaatgct tgagaaaata
     1201 gaaaaaagtg ggtttaatgg gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga
     1261 aaaccacaac tagcttacga ttttgaggcc acttatgaaa cactgaaaga agtattcagc
     1321 atcttttcta agccgctagg aatcaaattg cctccttatt ttgattttgc tcattttgat
     1381 cagatggctg atatcttgaa tcagtttcca ttgacctatg tcaatgctat caacagtgtg
     1441 ggcaatggtt tgtatatcga tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg
     1501 ttcggcggca ttggcggaga gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt
     1561 tatacacgtt tgaaaccaga aatccaaatc attggtacag gtgggattcg gacaggacaa
     1621 gatgcatttg aacatctgct atgtggcgca agcatgttac agattggtac cgagcttcat
     1681 aaagaagggc cggaaatttt ttctagaatc ataaaagaat taacgcagat tatgtcagaa
     1741 aaaggatata cgtcaattga cgaatttaaa ggcaaattac gcaccatttc atagcaaaga
     1801 gacgaaggtc atgattgatc ttcgtctttt tttataaaaa acactcgtct gttcattcct
     1861 gtgcaagcgt actcattgta tgttagacga acttgtggga aaataacaga ggcaaaaagg
     1921 aggataatat gaatgatgca acagaattag caaaagagct taaagaaaaa gaatttagtt
     1981 ttcaagaact agttacggat atacagaaaa aaataaagaa gcaaaatcat gaattgaatg
     2041 cgtttgtcgc gcttgaacca ttcgagagta attcccacga gctattgatt ccccagtcag
     2101 aaaaagggcc attggctggt atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg
     2161 gatggctagc tacttcagga tctcgtttat ttgaaacaca ccgagcttct catacatcta
     2221 attatgtgcg gcaagcagaa gcgataggtc tagttccttt tggacaaacc aatgcgccag
     2281 agtttggttt caaaaatatt acagacccag tcatctatgg cccagcaaga aacccttgga
     2341 accttgaatg tacaccgggc ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa
     2401 tcgttccttt agctggtgct agtgatggcg gtggttctat tagaataccc gcttcgtttt
     2461 gcggattgat tgggctgaaa ccttcgcgag ggacgatgcc agttggtcca tatgcttgga
     2521 gaggatggca aggagctgct attgatttcg gcttgacagt ttctatgaga gacacggagg
     2581 ctttatttta tgggatgaga agtatccatt ccggtgcgcc atatcaagta tcgccagttg
     2641 agtggcaaac acatccaaga aaaaaacggt tgaagatagc tttttgtgtt gattcaccga
     2701 tccactcaca gattagtgaa gaggcagtac ttgctgtaaa aaaagctgta gatttccttg
     2761 gaaaagaagg gcatgatttg acagagattc cttacccact agatggtcgt aaactgatca
     2821 cgtcttatta tcagatgaat ggcgcagaaa cagcagcaat gatccgctcg attgaaacag
     2881 gcatccagcg agctgtcaga aaagaagaac ttgaacccat ttcttggact ttgttccaat
     2941 atggtcagaa gctctctgcc gctacttaca tcgattctct gcatgtatgg gatgaagcag
     3001 caattgtcat ggaaaaccta catcaagaat acgatctatt cctttcacca acgactgcat
     3061 ttaccgcccc taaaatcagc gaagatttgc aaagtgatgc gataagagca cagatggaac
     3121 acatcagtga ttgttctgaa gtagaaggtt tagacgttgt ttcttccatg tttgaggaga
     3181 gcttgaagat cacaccttat acacagttgg ctaatctgac tggacaacca gcaatcagct
     3241 tgcctactca tttgacaaaa gaaaacatgc ctctaggaat ccaatttatg gctgccagag
     3301 gaagagaaga tttgctattt caaatcggct atctatttga agcaaatcat cagttccatt
     3361 taccaaatcc atggaaatag cagaaacaag gagaagaaga atgaagaaaa aaagattgtt
     3421 tgctctaata actagtgcct tttttatttt aagcgcttgc ggtacagctg ccgctaatca
     3481 ggaagataac agctggagta atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg
     3541 cacactgttt cccgcatctt attataatga tcaaaatgaa ttagttggtt atgatgtaga
     3601 tttggcaaaa gaggtggcta aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt
     3661 ggatggacaa atcacttctg tttcaaaaag agaatcagat tttgctgcga acgattttgg
     3721 tatcacaaaa gaaagagaaa aaaaattctc cctttcagag actttcaaat attcatttga
     3781 cagtatgatc gtacgaaaaa aagatgattc aggaatccac tcacttgaag atcttaaagg
     3841 gaaaaaagca gctggcgaac ccaatactag ctatatgcgt ttagcggaaa aacacggagc
     3901 taaattagtc acatatgaca atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg
     3961 tcgaacagat gttattctaa atgattatta tctgcagaaa atggccgtat ctgctttacc
     4021 agatatccct gtaaaaatac tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt
     4081 attgaaagaa ggaaatgatg ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa
     4141 agaagatggg acgacaaaga aaatatctga aaaatatttt caaactgatg tttcagtcaa
     4201 accgaaagaa acgatggctg agtcggtgag tgagtgatgt actttcctct aattgatttt
     4261 tccctcatgt ggacttcact tcctttcgta ctgcaaggct tggtatacac attagggatt
     4321 ggcttcgtgt cgtttctttt aggaaatctg gtagggttgc ttttgacagt tttaggtctt
     4381 ttggattggc tgcctctgaa tgtatttatt cgtttttatt tatcgttctt tagaggcatt
     4441 cccgcactag tcctgctgtt tctgttatat tttgggttac cttatcaatt aagtgcctta
     4501 acggcttcag tcatctgctt tacgattacc agcagtgcat ttattggtga aatctatcga
     4561 ggatcactag caggcgtttc ttcaggtcag tgggacgctg gtttagcttc tggtttttct
     4621 ttctttgggg tattgaaata tatcgttttg ccgcaagctt ttcgaatctc agtaccggca
     4681 ctcagtaacg tagctatgga tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg
     4741 ccagaaatat ttcaaaaagc aaagatcata ggcggtcgga cattcgatta tttttctctc
     4801 tatattttag ttgcactgat ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag
     4861 tatttagaaa aacgttctat gcatcagtca atctgaaaaa tagaaatggt gctagcgtgg
     4921 ctggcaccat ttctattttt tgtttcttgt atattctgcc tagtatttta aaaccatttc
     4981 atgtaaaatg taaatcgaaa atatgttcgg aggtagaaaa catgaagacc ccgctaacca
     5041 tcgaaataga atcctcgtta taccaatatt gcatcgagca aggcggcttg gttgtagaag
     5101 aagtcacgat gcctgatgac caaggaattg tagatacgct tagctgcttg acaaaatttg
     5161 atggaagccg agaatggcga tgctatgagc tgaaagtgac aaaagcagat tttcgctcta
     5221 cagccaaact gtcatttgtt ggacattata attattttgt tttaccaagt aaactatatg
     5281 aagaagtaaa aactgaaatc cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg
     5341 ttgaagagga gatgcctgcc tctggtacat ttctgattgc gaaaaaagca gcaaagaaag
     5401 agcttgctgt accggaagaa gctttgacaa accgcttcat ggcttcttta ttcagggaag
     5461 taagaaaagc aaagcaaatg gagcgaggcg taaaatattt tccaacagat caattgtaca
     5521 aagaattgaa aagacgttca gaaaatcaag atccattttc taacgaacga tattatgaac
     5581 ggtttttaga ggaaatagct agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc
     5641 ttcagcatga ttatgaatat ttgaggcaac aacagcagat ccgtcggttg cctacagagc
     5701 cattggagtg aaaaatatgt actatcctta tttaagagga aaacaatttg acctattagc
     5761 attaaaagaa gcactgtcgc gaggattgct ctccaataaa atccaaccag tgatcgaacc
     5821 agtacgtgat tccgctacgc ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcg
     5881 aatcgctgtg atccaaaatc cccaagtagg acaattcaaa ttattcgatc agcatgtgca
     5941 cagttggaca gtcaaagaaa atagctctgt cgtccctgca cagatcttaa cgccagaaaa
     6001 tctcagtgaa gtactggatt cacctccagc gtttcttgtt ttcgatggac agcactaccc
     6061 aaaagataca gaggtgtgga aacagttggc aggagttgat tcgaaatttt tgataccaga
     6121 tactagtcgc tttcgcatct ggctgcccga aaacaaaatt gtgatccgtg actcttttca
     6181 aacgagaaag catgttgaaa gttatgcaga taaaacagat gactttttta gtgatgacta
     6241 tctttttttc cacgcagacg gatatattgg attttctgat ttcacgatcg aaggtagccg
     6301 ttatttcgat aaagggttcc ctagccgagc gcttgctatc catctaacgt atattgatgc
     6361 ttacggcaat atacgcgtga aacattttgt ctctgacagt aacgactctg ctaaagacca
     6421 agcattgaag tttcttgaag caggagataa aatgaaaaaa tggatcatgc gtcaccatca
     6481 tcaactcttg attacttcag gaatgattga attattggct ctttaccagc aacaaaaatt
     6541 ccctggactg ggagtgttga aaaagtggtc acttatgcat catttggaac ttattagtca
     6601 cctgctagat catccaaaag attggcttaa atattattca aaagttcagg aactatatga
     6661 agtgatccaa tgattagata atgtaaatga aaaaggaata gaaaagagga aactggatgt
     6721 atattcggca aacaaggaaa gaagaagtag aagaagtggt agaaatcatt aatgccgcag
     6781 cggatttcat tgcttcgcaa ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag
     6841 aaacgatttt gaacgatatt gaaagaaaag aaagctatgt attaatagtg gaagatcaaa
     6901 ttgctggaac agctgcatta gtctcaagcg tggatcccgt ttacacaaaa atagatggta
     6961 gttggaaaga atcaactggt ccttatttat cgattcatcg tgtcgcttta gcagaaagta
     7021 ctcgaggaaa aaaactagca aaaccgttct tagaacattt gttgacgatt gcagccagca
     7081 aaaatatcca agatatccgt atcgatactt atccagctaa tgaaccgatg gaaaagacca
     7141 tctattctgc tggattcact tatcaaggga tgattgaatt tccttttgaa cacggcgaaa
     7201 gaaaagcata tcaaataatc atcaattgac tataaaatca tctgagcaaa gataaagaca
     7261 ttaacactac tgaaaaaaac aatcatatga tagccaagag gttgtaacag aagtggccag
     7321 cttcaaaaaa caagaaagaa tttccgaaaa tgcttctcaa atttttgtgg aattttagcg
     7381 tattttacga aatagctgct ttctgaaact cccttcatcg agaggtcgtg acatagcttt
     7441 tgtcacgacc tctcggctta tcctacgagt attattcgat acatttatat caataatcct
     7501 ttttttattt tatctgcagc ttcttggaac gctccatcgt ttgacacgac taaaagtgag
     7561 gggatagctt tcaaacgttt caactgtgct aaatcttcta cataaaccgc cagtctggct
     7621 gaaatctgtt cagatgaatc tccacgtttt ttcaggcgcg attgcaatgt ttctttagag
     7681 atcgtaataa agataggacg gactaccgtc ccgaaatact catataaatg ccaaaaacca
     7741 tttgctgtca aaacggcgta acaatttcct actgtcagtt tctttttaat ttctgcttta
     7801 ctggaaccat atttatgttg agcatattgg tcccactctg caaactcatt tcccttgatc
     7861 atctgattga atgtattgtc agaaacaaaa taataatcct cttgatcttt ttccccaggt
     7921 cttggtgatc gattcgtgta agtaatgatc ttttgttccg gctgaaaaat agcttctgcg
     7981 agtgaagttt ttccagaacc agaaggaccg ataaatacat agcaataatt cattgtcatt
     8041 tctcctttga tgattgaaca agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa
     8101 gtaactttgc ttttttgtat attataccag caagccagtc acaatagcac ttaaaaagct
     8161 gactaaagtc gctgttagca aaattttcaa tccgtgtttt gcgacaagat ttcctttttc
     8221 ttcatttaat cccttcatcg caccagaaat gatcccgata gaagagaagt tggcaaatga
     8281 aacgaggaag acagatataa ttgctgttgt acgctcagta aaatggaaat taccatttgc
     8341 taattctgtc atagcaacaa attcatttgt aaccagttta gtcgccatga tactaccggc
     8401 atccactgct tctttccatg ggattccgct gatgaaggca agaggggcaa agatgtaacc
     8461 taggatctct tggaaagtga tgccgaatat cccgtggaag atagcattga tcatggcaat
     8521 caaagcaaca aaaccgataa gcatagcagc aaccgtgatc gccacatgga aaccatcaag
     8581 aatgtattct cccaacattt ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc
     8641 atcttctttt tcttctaata catagggatt tacaattgaa gccagaatat aaccgccaaa
     8701 taagttcaaa acaagggcag tgatcacata tttagaatcg atcagtgcca tataagatcc
     8761 gacgatcgac atagaaactg tagacatagc cgatacactc atggtgaaca aacgtttctc
     8821 agataggaag ggtaattcct tttttatgga aataaaaact tccgattgtc ctaaaatagc
     8881 agaagctact ccattataag attccaattt gcccatcccg ttgattttac ttaatcctag
     8941 accaacagct ttcataaata atggaagaat cttgatatag cgtagaatac cgataatagc
     9001 agaaataaat acaattggca tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc
     9061 tacaccggca aaaacaaagt caacaccttg cccagcaaaa gcaagaagat gatcaaacat
     9121 ttttgccaat acagaaacaa ccgctgtacc aaaagttgta cgtaataata cgaaaccaag
     9181 aacaagctgt aaaacgaaca tcacaattag tggtttcaat ttgattgctt ttttgttact
     9241 gctgatcaaa aaagcaagcc ctaatgtgac aaataaacca ataataccta ataaataact
     9301 caaataatca ctcctattcc aaattccgtt ttattttacc tgttttgcaa ataaaatact
     9361 aatctttagt gaaattttca ttactttttt agagtgaaac gcattcattt tccattagaa
     9421 aataaagcga acaaaataaa aggtttaaaa agtgtaacgt cttagtaaag tctataaaaa
     9481 aacgaaacta tcgattaagc taatagtttc gttttcaaca tttataagta aactttttct
     9541 attggtaata tagattttcg gaagggtaga caggtgcgca ggtaatatcg attcctagtt
     9601 ttttcaatgt ttgttcatca tttttattga ccatcacagt agagtgggct tgtgctccct
     9661 caagttcagc tagtttatca taagcaactt gagcgattgg attcgttact gcactgattg
     9721 ataaagcgat caagacttca ttgatgctta gtgcatccaa agaggaatga agtgtctttg
     9781 atttcaatcc ttgtattgtt tcaagaacta atggtgacaa taaaggaatg tcatctgcga
     9841 tatgggctaa atgttttact gcatttaaga taactgccgc tgacgcatcc atcaatgaac
     9901 ttgtacgccc ggtaatgatg acttcatctg gtaattcgat tgcaatcaca gcagaaggat
     9961 cttttgtagg actttgcgct tgaatcttat ctgcatagtc atgggcaggg actaccacgt
    10021 ttcggtcttc aggacgtaaa ccgacttctt ccataatcag tttgattcga ttaactgctt
    10081 cttcgtcgat caatcctttt ttgaagtcgc attctgtttg gaaataacga cggatgattt
    10141 cttgtttaga ggcttcttgg acaacggtat catccacgat cccaaatcct acacgattca
    10201 cacccatgtc agtaggagat tgataaacag attctttacc agtaattttt tcaataatac
    10261 gtttgattac aggaaatgtc tcaacatccc gattatagtt cacagctact ttattgtagg
    10321 catcaaagtg gaaggaatcg atcatattga catcttttag atcgactgtg gctgcttcat
    10381 aagcaatgtt cagcggatgt ttcaacggaa cattccatac tgggaaagtt tcgaacttgg
    10441 agtaaccagc tgcatgtcct ttttggcttt catgatacag ttggttcaag gaagtagcga
    10501 gctttccact tcctgggcca ggagctgtca ctacaacgat tggtttagtt gtttcaatat
    10561 actcattttt tccaaaacca tcttctgaga cgattttttc tacgttgact ggatagtctt
    10621 cgatttctga gtgtttatag accttgatgt ttcgtctttc tagtttattg ataaagactt
    10681 tcgtggcagg ctgtccacta tagcgagtga taacgacact gttgattaat aagccataac
    10741 cacgtaattc atcgattaac cgcaagatat ccatatcata agtaatccca taatcaccac
    10801 ggatcttatt acgttcaata tctccagcat agacgcaaat cagtatttca gcttgatctt
    10861 tcaatttttg cagcaatttg attttcgcat cttcttcaaa tcctggaagt acacgtttcg
    10921 catgcttgtc gtcaactagc ttcccaccaa attctaaata taatttgtca tagtggttca
    10981 ctcgttccaa aatatacgct gactgctctt caatatattt ttctgaatca aaaccaattt
    11041 ttttcactag gttccctcct taagtactaa agcatttttt catttttttg aggattcgtc
    11101 aactggaaga gcgaaattcc tcaaaaaaac aaagaaaatg gtttaaacca acttgtctag
    11161 atagttattc attggtatga tagtttttga taaggaaggt gctacatgaa aaaaagacag
    11221 aaaaagaaaa acgcatataa acactatatc cgttcgattt ttaccggtta tgaaagaatg
    11281 cttgaagatc ccgaattgga acaattgacg tttacttatc taaacgaaga aacgcagcta
    11341 actcgtgatg agcatcagcg cattcatttc acaacaagag atctgcctag taaataaaaa
    11401 ataagataaa ggtcatcgga ttcgattctg tcctatcaga tggaaagact agttgatcga
    11461 aaaaaaggct gtaccaaatt ttggtgcagc ctgttttatg gagcattgcc cgctcttttt
    11521 tataacaatt ttttacagaa aatggtacta ttgaagtatt aataagtgaa aaacagatga
    11581 gtaagaggag gcaagtagta tgaaagagcc agatacaaat gcaaattatg agccagacga
    11641 actagaggag acgaatgcgg atcaggatac aggacaagaa tcgtcttctt tttacgatat
    11701 caaagaaaaa gcaagcatga atctttccca attattagaa gacttacagg cttttgaaaa
    11761 agctgtccgc gaagaagata tccctgagat ctaccgttta tacaatggcc gattgaatga
    11821 agaattaaaa agaagctcaa atgaaaatca cgagatcgat caattgctga tgcgtaagat
    11881 ccatgatcgt tttttacagg aatttccttt tatggaacaa gtagaaaaca tctcgccaac
    11941 gatgagctat tacaaaatcg gcacttatta ccatgatcgg cccacggtcg gtattgatgc
    12001 aagtctgcca gaaatttttg ttttgcctaa gatcgatgaa gagtgggaga aatattccca
    12061 accggagtca acggactatg acaaaaaaat caatgagcta gacgcaaagg tgatcactgc
    12121 tcagacagaa attgaacgtt tagatgaaca aataaaagaa atcaatcgac aaatgactga
    12181 tttgaacgac aataaaggat tcttgaatcg taaaaaaatc gaggaagaaa ttcaagaatt
    12241 agagaagaag aagcaagtac tatctaatga aaaattaggc tggcttcctt atattgagac
    12301 gcctgaaaca atccagcagc aaaaagaagc attgaagcaa gaagcaagag cagaccagct
    12361 tcgtgcagcc atcgtagaaa aagaacaaag gcaaatcaga cgctatttcg gtagcaaaga
    12421 gggattcggt caagcaatcc atgaattctt gatgaattat cttggcaatg agaatcctaa
    12481 taatcaatct aatgaaggag gttccgagta tgaatgaaca cgatgaagca gaatggacaa
    12541 aaaatgaaga acaaacagaa gatcatgaag aaacgaacac ttcattggaa gaacaaacaa
    12601 gtaatcctct ggatgacaca gaagaaatcc ctatgctaga ggaaacaaaa atacacgaaa
    12661 aagaaaaagt aactccgacg aatacgaata ctgcagaaaa cacccatgct tacgaaataa
    12721 ctgaaaatcc cgggtattta gaaggaaaag agcaagatca tcaagatatc gtcagtttga
    12781 ttgaaacagc ggaagcagaa ttagcggatt tacgtatgag aaaagatttg atcgaatcag
    12841 attttccaca attattagaa tcatatgatc gttttatatt gaatgaagaa ccaatctcca
    12901 cgatcggaaa gacaagcctg atcgaatact tcacgtatga attactgaaa ccgttgaatg
    12961 atattggtct ggaacggtca aattcagctt atgacacatg gaaaacaaga catttttcga
    13021 tcaattatac gttgaatgga caaaacgaat tagtcttttc ctttgtatta ccgaccatcg
    13081 atcaacgata ccaagtggaa tcgatgagtc tcctaaacgt atcaccagag acaatggaaa
    13141 tcaatgtcca agatgaccgg gtgctttctt tgatccgaca ctggtcagtg gatcgagtat
    13201 tctctgcagg gcagatcacg atattcaatc acaaattgaa tcaattatta gcccatgcaa
    13261 gaacacttgg ttttaccgtt aatcagacat tactagacaa tacgaagcca cttcgtttga
    13321 atcttcagag cgaatttgaa ttgacgaatg aagtattgga tgatattttt atcgtggcaa
    13381 tgaaaaatcc atcctacgat atggaaaaga tcaacgaaac tacttatcaa gtacgattag
    13441 ataaaggaca gtctttaacg ataacaacaa acgaaaaaga tcaaacagtc ttgtcgatct
    13501 catctggaga ctacccacga tctgtcattg atttctttat caattacgaa ttcttggtcc
    13561 cattaatggt gagaaagtcc tgattggata agttggatta ccagatgtca ttcagataat
    13621 tctgttccaa aggacttgcg gcagttatcc agaataattg tcacaagtct tttctgtatg
    13681 tactaaatgg acgtgaataa cttgctgatg aaggagggat ttcattagga atgtccacaa
    13741 ataaaatagc acagcttagc ttattgtctg ctgcttgtgt agcaggtagg atcgcttttc
    13801 aatttattcc gaatttccag ccaatgactg ctattttttt atttatagta ctttacttaa
    13861 gcttaaaaga tgcgttaatt gtcatgagtc tttctattgc gatcagcagt ttttattttg
    13921 gtgttggacc atgggtcatc ggccaatgga tcagctatac tgttgttctg agtttgtttt
    13981 caatcgtctg cttgagaaaa acagtgcaaa ggaatctatg gttaaaggga gtctgttttt
    14041 ttctggcggg catggtttac ggaataggta tgaccgtttt tgatacgctg ttatatcgtt
    14101 tgcctcaacc ttggatctat taccttcaag gggtgtcgtt tgatttgatg cacagtatag
    14161 gcaatgttgt gttctttctt gtttttctgc cagtcgtcaa acgtttttac aatcattcag
    14221 gaggaaaaaa tgaaaaaaat aatttatagt ttgcttgcaa tgagtgtcag tatactcatt
    14281 ttgacaagtt gcagtacaac ctatacacaa tcggcttcca accaaaagga ggaagtaaaa
    14341 acatcgcaaa aagcaacaat cacgttacaa gaaaatggtc aaaacttttc ggaaaaagaa
    14401 gtgttcttca aaaaaggcga tgatttactg agtattttga aacgaaattt tgaagtcaaa
    14461 gaagataacg gcttcatcac ttcgcttgaa gggcactcac aggatgagaa aaatcaactc
    14521 tattggatgt ttactgtgga cgggaaaagt gctactactg gtgccaaaga gatcaaattg
    14581 aatgatggac aatcggtcat tttcaatttg tctaaactat aagtttcata aaaaactgtt
    14641 aaagggcgaa tattgccata attcagtgag ttcagttgat gaaagaagga aaataacatg
    14701 gaaaatttta aaaaaagcgg aatgttttcc gtaattgctg ctctaggggc taatattcta
    14761 gttgctatca gcaaatttgt cggctatgca atcagtggca gtgccgccat gctaaacgaa
    14821 agcatccaca gtatcgttga ttgcagcaat cagattttgc tgttattcgg tgataaacaa
    14881 gccaataaag gacagagcga gttgcatcaa tttggtgaag gacgagcaaa atactttttc
    14941 agtacaatcg tcgcaatgat gcttttcttc ggcggtgggg cacttggggt gatggaagct
    15001 tttgaaaagt tgacgcatcc atcccatgaa gtgggtaatc cgatcattgt tatagcaata
    15061 ctgttatttg gtttggtaat cgaaggaagt tcgttacgcg tggcaatgaa agaaatcaaa
    15121 gaattgaata ctgaaaaact ttccacgatg cgctttttgc gcgaaagtcg acacagtgaa
    15181 atactgatta tttttacgga agacttgtgt gctgtaatcg gtttggtctt ggctttagca
    15241 ggaacaatat tgacttatgc aaccgggatt gctgcatttg atgcgatcag cggattgctg
    15301 atcggtttct tgctgatggg agccgccatt ttcctagcaa aagaatttta tagtctgatc
    15361 atcggtgaaa gcgtgacagc aagcgattta tcaaaaatca agttagcttt tgaacgtcct
    15421 gagatcagtc ggctgatcga tataaaaaca gttcatttaa gtccaacgga gattttagtt
    15481 gcagcaaaag cagatatcgt tggtaacaaa gagaatgaag cttactcggt catcaatgat
    15541 attgaaaaaa atatgcgtca gtctcttcct gacaagaaga tgtatatata cattgaaaca
    15601 gataaatatg acccaaatta ttctcgtaaa taaaacgttt attcatgaat tgaagcaaaa
    15661 atgagaaaaa tataatcttg tttttaaata aaacggctac aatttagcga atttatgtta
    15721 caatgagtcc gctgtttatt tgttgtaatt aaaggagata ttttaatgaa caaaaagaaa
    15781 agtgcgccat ggcttcaagc tttgcatgca gtgatgccac tttgtataag ctatatacca
    15841 gtaggattag cttgcggagt attgttgcaa aaagttggat ttgatcctct cttatcagga
    15901 ctgttatcga ttctggtctt ttccggtggc gcgcagtttt tagttgcatc tatgcttacg
    15961 acgcaagcat catttgcaac gacattattg atggttttct ttttagaatt acgctataca
    16021 ttattaggag caagtcttgc cggttttatg aaaaaagaaa agcggacgtt tttggctgtc
    16081 ttttctcaat cactgaatga tgaaaactat gcggtgaact acttaaagtt ttcaactgac
    16141 ccttcctgga ataaaagaaa ggctttatat gtcaattggt tctcaatgac tgcatgggcc
    16201 ggtagcaata tgatcggtaa ttttttcggc tcggtgattc gagtagatgc tgaccttgtc
    16261 cattttgctt tgacggccat gttcattttc atgtttatca tgcagatgaa aagcgcacta
    16321 ctgatcttta caggtttatt ctcaggcgta ttaggggtcg tattcatggt attattccaa
    16381 aatactttcg gattgattgc agcaacagtc attgcttcat ttgccggatt tatgctggag
    16441 aaggcattca aaaaagaaaa agctaagaaa ctaagagacc gcggtaaaga tgtcaatgag
    16501 ccgctcttca acttcccgga acaggaggcc aatcaccatg actaaactat atttgctact
    16561 tttagttgtt tgtctgttca tcgtggcata tatcccgcgc ttgttcccga tgctttattt
    16621 tactcatcga aaagtgccat cctggttcag tgactggatg aaatatgtac cggtggcatt
    16681 atttgcggcg ttagctttta aagatgtttt cattactcat gaacatctgg atattgcttg
    16741 gaatatcaaa atagctgcaa tgattctagt agcaggcgtg gcttacaaaa cacgttcgat
    16801 ggcgttgtca gttttgacag gacttgcgtc tgtctttttg ctgtctatgc tttaaactgt
    16861 tttattttat taaaaacaga gattgcgaca taagttgttc aaactgatct atccgaactg
    16921 catttgcaac agtcaattct ggatgcaagt ttattcgtag ggataaaaaa gattagtgtt
    16981 ggcttatgat gcaagctctt ttttatttta ggaattagag agggatttgt ccttctatga
    17041 ttttttgcta taatagggaa gatgtttatt ttatgaaaga atagttgagg gaatttaaat
    17101 gaataaaaaa ttgatgcaag gaacattttg gctaaccttt gctaatcttc tatgtaaagt
    17161 tttaggggta gtctatttga ttccctggct aagtatgatg gggaacaatc aagatggtat
    17221 gcttgctacg acattgtata atgttggcta tcttccttat ggattgttcc tgatgcttgg
    17281 tacagtcgga tttccaaatg cgattgcaaa aaaagtagct gtagccacaa aagaaggaga
    17341 taacgctgct tgtcggctga tttttagaag tacgatcaat atcatgtttg tcatcggtat
    17401 cgcctctgct gcactgatgt atttatttgc tcctttacta gccggaatca gtccgattgc
    17461 taacgttaat aatgggatac tagctatcag aagtttatgc ccatctttga ttgctatccc
    17521 aattcttagt gcaatgagag gatatttcca aggaaaaaat gatctgcggc cttatggaac
    17581 ttctttgatt atcgaacagg ctgtgcgagt gatcgttatc ttggctggta cttattactt
    17641 gcgcgtattg actgacggaa ccatattaga agctgtattg atcagtacag tcgcttcttt
    17701 cttcggtggg ttagctgcga ttatccatat gtatatcgtc ggacgcagaa aagacttctt
    17761 cgaacttaaa gattttttga tttccagccg ttatttcgaa agagaaaacc gatctgcctc
    17821 tgtctctatc attcgggaaa cactaccgtt tatttttgtc ggctcagtca ttactatcgt
    17881 tcaaatgatc gaccaagtaa cgatgaaacc actgcttcac tttttccgtc cagagatcgc
    17941 agatcagcaa ctggaattct tattcagccg tgcttctgtc aatccaaata aattgacatt
    18001 gatcctgatc tccatggtag gaacagtagc tataagcagc ttgccaatat taagcacgat
    18061 gaagaaaaaa gatcggatac aaatcgaaaa aacagtagga gatagttttt cgattgcgtt
    18121 attgattctt cttccttcat tgactggaat gtctttatta gctggaccac tatacacatt
    18181 gttttttggc tatgatcctg aaagtgtcgg atatttccaa atggctttgc tagcttcttt
    18241 gtttttctct ttattcacga tcctatctac gatgcttcaa tctttgaatc accatcgttt
    18301 tgcgatccga ttaactgtag aagcaattat cctgaaagtc atcttccaag taatcggatt
    18361 aggattagtt ggcggatacg ggatgagctt atcaaatggc ttagcattcg gtattgtctt
    18421 tgttcgcggc tatcacttta tgtgcaaaga ataccgaata gcacctttag caaagatcag
    18481 caattttttc ttaaaaactt tccgctccac cctgattatg cttgcagtat gttttgccgt
    18541 tttctttttg ctgaatcagc gattgtcaat ggaatcaaaa agctatgcaa tgatttattg
    18601 tgtggctgta ggaagtattg gcggcttagt atttttattt tctcaattcg gaaaaaatgg
    18661 gtttcgaatg ttgaaaaatg ttaaacatca tagcagaagc aaagaatagg ttaactaatc
    18721 gttttttgct gtcacttgaa aaacggcaac tcgtatgatt acgcttgtcg tttttctatt
    18781 ttccaatttt agtttcatat ctaatcttac ttatgatata gttataaggt ctggaaaaat
    18841 tctttgaaac gaggaaatta aacacatgaa acttgcagta gttacagata gttcggcata
    18901 tctgccggaa cgtatcaaga accatcccga cttattcgtt attccaatcc ctttgattat
    18961 ggatgggaaa atttataacg aaggaatcga tatcgaagcg gatgaatatt atggactttt
    19021 aaaaaacagt aaagattttc ctactacttc acaacctgtc gtaggggaag ttttgggttt
    19081 atatgaggaa ttgaaagaga aagggtatga cacgatttta agtatccatc tttcttcagg
    19141 gatttctggc tttgtcaaca cattatttgc gatgaaagat gacatcagcg gagtaacggt
    19201 cattccttat gactctaaga tcactagtat gccgatggga cacatggtag aagctgcctt
    19261 agacttaaat gatgaaggtc agtcccttga tgaaatactt gcacatatcg atcgaatccg
    19321 agataatacc tacgcttatc tgattgtaga tgatttgaac aatttagtac gaggaggacg
    19381 tttgacaaat ggtgcagcgc tgattggcag cttattaaaa atcaaaccga tcctgacatt
    19441 ttctgaaggg aaaattgttt tattcgaaaa aatccgttca agtaaaaaag catttgctcg
    19501 agctgaagaa attattggta gaagaaataa cgaaatacaa ccgccagtca aactttacgt
    19561 gatacatgca aataatttag aagtagcgat tgcggagaaa gagaaattgc agaaaaaata
    19621 tccaaatgca gaaatcgaaa ttggtcattt cggaccagtc attggtacac atttaggtga
    19681 aaaagccatc ggcattgcca tttcagcgca ataattcctt ttattcaaaa aacataccaa
    19741 aaatattcca acatcatctt ggactttcta catgttacta atgagcgtgt aaaagaacga
    19801 gatggtgttt ttatttctat caatgaagct ctttttcttt gcaatcctca cttcaatcct
    19861 ctataatgtc gcatatagtt tagtaaatga gtaaactact aatttactta tttactaaaa
    19921 ataaaaggat gaggagttaa aataatggaa ataccaacaa atttaaaaca taaaccagta
    19981 atcgttgtag aagactatga taaagttgat ggaagaaatg cattaaatac ggatgcaaaa
    20041 gggctttcac tgggccttgc tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag
    20101 gtatggcgac atactggaga aaaatggtca cgacagtcgg aagaattacc aatcacacgt
    20161 attttagatt tagcgatctt agctgcacaa ggaagtttat acttccaaga tgcttatcgt
    20221 tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca tcattggatt acaagggaac
    20281 cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg atgaagacat cattttgtat
    20341 tacgatacac tacaaaaaga cggagaactg attggggaac gattccgtat tttaaaacgt
    20401 cttttagatg agctaggata ttaatagaca gagatgatca aaaggggaag agaagcatgg
    20461 agaatttctc actaacagaa aaccgaacct tttcacggct agaaaagcaa atgatctgga
    20521 agaaaccgaa aagccatcgg acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag
    20581 ggaattggca agatcctgaa atgaaaatca gtaacgtact tttggaagga gatgccgggt
    20641 cggggaagac acaattagcc aaagcactat ctgctgatct gcaacttccc tatacaaaag
    20701 tgacctgttt tgcagatatg gacaaatcag atgttttcgg agccttatta cctgtagtag
    20761 attctaataa ggaacaagac caagaattac tagaagctat ttaccaaaca gatacacttg
    20821 aagctgtact gacactgatc cagaaccatt acggcattga tcctttttct gctaaagaaa
    20881 aattagcaga gctagttcaa aggatcgaag ctgattatcc agatgcaatc cattacagct
    20941 attacccttc tgaaatcgtt cgagcgattg aaaaaggata tttattagag attcaagagc
    21001 cgactgtcat ccgagatgcc tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg
    21061 ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc agattgcgtc attgtgatca
    21121 ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga atctttaaga gatcggatgc
    21181 aacatgcgga aaaaatggat cttcctgcct tagaagtcat ggcagaacgt gcgatggcga
    21241 aaactatgat ccaaaaacaa gaacttctct taaagatggc agagattatc cgtttgttgg
    21301 atgaaactgc aaaagctaac gccatcaaag gtgtagcagg aatgcgttct tatttttatt
    21361 gggcaaatac ctataagcaa ggacaagatt tactccagtc gatttatcca aaagttttgt
    21421 ataaattatc cactgattca gatgaattgg caattcttga acaagctttg tctgacagtg
    21481 gattgctact ggaacttcag gacatattga gaaaagaaaa atggggtcat cctcaatctg
    21541 agcatacaaa aggaagaacc attagcgccg aagaagcaaa tgaacgaaac atcactgaaa
    21601 atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg
    21661 agggagaaga gaaacaagaa gaaacaatag aaaaaaacga gattcctcct caaatgcaaa
    21721 aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt
    21781 ctcaagaaat gtctgcttct gacatggaag cacatgataa ggaaatcaag aagcaactga
    21841 ataaagaagc gcgacaaatc atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc
    21901 accgaccagc tttccaagga aaaacgccgg aagcacgtga gctacacatg caagtaatgc
    21961 caatagtaga atcacttagc cggcaaattt tagagttact ggataatgaa caaacagaga
    22021 cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg
    22081 atttgagaaa ttttgacaaa aagaacccgc cacatgagca accttcttta gcggtagctg
    22141 tacggatcga tgaatctggg tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag
    22201 cagcgattgc cattgccgaa ttttctaaga aagtcgatat cccattgttg atttacggag
    22261 atacagcaga ccgttcgtca agagaaaaga cttctttgtt ttcttataaa gaatttgaag
    22321 acggatttca atggttaaat gaaaaattag tcactatgaa accaaggcaa aacaatcgtg
    22381 atggtgctgc acttcgttta gcagcagaaa aattaaacag acaatccgca acaaccaaac
    22441 tgttgcttaa tattagtgac ggtcagccaa aagcgttgcc ggattataca ggcaaaaaag
    22501 caaaagaaga tatccagtct gttttgaaag aatatgaacg tcaaggaatc ctatttgtct
    22561 ccgcagctat tggccaagac aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg
    22621 tagatattac tgacttgaat gaatttccca agcaaatgat tcaactgatt gcccgctatc
    22681 tatgataaaa taaagctcaa cgaacgcact tagcagattc gttgagcttt tcgtttctag
    22741 ttaccggtaa caaggatact tctaaaatag aatcggttat aatcaagagg gaccgttaaa
    22801 ggagtgaaac gatatgatac aagaacaaaa atggtggaaa gaagcagtag gctatcaaat
    22861 ctatcctgct agtttcaaag atagcaatgg cgatggtcaa ggagacatca atgggatccg
    22921 tgaaaaactt aattatttga aagatcttgg tatcggcttt atctggatca atccgatcta
    22981 tcaatctcca tttgtcgata atggttatga cgtaagtgac tatcaagata tagaagagag
    23041 attcggaacg atggaagatt ttgatttatt gctaaaagaa gcacatgaat tagggatcaa
    23101 agtgattatg gatcttgtca tcaaccatag ttcggatcag catcaatggt ttgaagaatc
    23161 gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt tgggtcgacg gggtagatgg
    23221 caaagaaccg aataattgga catcgatttt cggcggttct gcttgggagt attctcatga
    23281 aactggacag tattatctgc atgtttttgc aaaagaacaa ccagacttaa attgggaaag
    23341 cgagaaattg aaagaagaac tattcaatat gatccgatgg tggttggata aagggataga
    23401 tggatttcgt ttagatgcga tttctcatgt aaaaaaagat gaatattcag taaaagccac
    23461 agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt
    23521 gaaacatgtt tttgaagagt acgatatcat gactgtcgga gaagcaagtg gtgtcactgc
    23581 agaagaagga ccacaatggg tagggaaaga cggttatttc gatatgatat tcgaatttga
    23641 tcatatccat atctggcagc aagaaaaaga agggcaatta gatgtcctta aattgaaact
    23701 tgcattaagc gcttggcaaa cttcattgga tggtatcgga tggaacgctt tatatatgga
    23761 aaaccatgat gttcctcgtg ccgtttcagt gtttggagat actcgtcccg atttttgggc
    23821 tatgtctgca aaagcaatcg ctatgatgta tttctttttg caaggtacgc catttattta
    23881 tcaaggacag gaaatcggaa tgacgaatat gccctttgaa tcgatcgatc aagttgatgc
    23941 agtagattcg aaaagacttt ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc
    24001 attggatatc attcgtgaaa caacgagaga caacagcagg acacccatgc aatggacttc
    24061 ggaacaatat gctggttttt ctacacatga accttggctg atcactaatc caaataccaa
    24121 aacgatcaat gtagaacaac aagaatatga accagagtcg gtcctgcaat tctataagaa
    24181 catgatccgc attagacaaa ccaataaagg tctgatatac ggttcttata aagaatatct
    24241 tcatgaacat ccacaacttt atgtctatga aagatattta gaagatgaac aatatcttat
    24301 tatggtaaac ttaacagaat cacttgctga ctatgaactt ccaaaagaag cagatcagtc
    24361 ctggacatta ctcttgtcaa attcctctag cggagaattt gaagctaaag gcatactagc
    24421 accttatgaa gctcggttat ataaaataaa caagtaaaac ttcctcgtta
//
LOCUS       DARPZJ010000037        23832 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.038, whole genome shotgun sequence.
ACCESSION   DARPZJ010000037 DARPZJ010000000
VERSION     DARPZJ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.038"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..673
                     /locus_tag="SLE23_001812"
     CDS             <1..673
                     /locus_tag="SLE23_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEI8468713.1"
                     /translation="SEIIGVSKYRLPQTCSVCRAQFHLLETRGCSGCQKPIHFNLEST
                     KKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWLNQYKFMGDIRLAGTFA
                     YKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARIPFQMLLKREKHLLAQA
                     KNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLFHAADCLQIAQPKIIRT
                     ISLAR"
     gene            801..1352
                     /gene="raiA"
                     /locus_tag="SLE23_001813"
     CDS             801..1352
                     /gene="raiA"
                     /locus_tag="SLE23_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEI8468714.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            1574..4108
                     /gene="secA"
                     /locus_tag="SLE23_001814"
     CDS             1574..4108
                     /gene="secA"
                     /locus_tag="SLE23_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEI8468715.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            4234..5335
                     /gene="prfB"
                     /locus_tag="SLE23_001815"
     CDS             join(4234..4305,4307..5335)
                     /gene="prfB"
                     /locus_tag="SLE23_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEI8468716.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            5440..6126
                     /gene="ftsE"
                     /locus_tag="SLE23_001816"
     CDS             5440..6126
                     /gene="ftsE"
                     /locus_tag="SLE23_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEI8468717.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            6110..7003
                     /locus_tag="SLE23_001817"
     CDS             6110..7003
                     /locus_tag="SLE23_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468718.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            7155..8603
                     /gene="cls"
                     /locus_tag="SLE23_001818"
     CDS             7155..8603
                     /gene="cls"
                     /locus_tag="SLE23_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEI8468719.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELSEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            8940..9797
                     /locus_tag="SLE23_001819"
     CDS             8940..9797
                     /locus_tag="SLE23_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEI8468720.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            9912..10832
                     /gene="pstC"
                     /locus_tag="SLE23_001820"
     CDS             9912..10832
                     /gene="pstC"
                     /locus_tag="SLE23_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEI8468721.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            10832..11716
                     /gene="pstA"
                     /locus_tag="SLE23_001821"
     CDS             10832..11716
                     /gene="pstA"
                     /locus_tag="SLE23_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEI8468722.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            11731..12537
                     /gene="pstB"
                     /locus_tag="SLE23_001822"
     CDS             11731..12537
                     /gene="pstB"
                     /locus_tag="SLE23_001822"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEI8468723.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            12553..13311
                     /locus_tag="SLE23_001823"
     CDS             12553..13311
                     /locus_tag="SLE23_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEI8468724.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            13324..14001
                     /gene="phoU"
                     /locus_tag="SLE23_001824"
     CDS             13324..14001
                     /gene="phoU"
                     /locus_tag="SLE23_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEI8468725.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            14238..15269
                     /locus_tag="SLE23_001825"
     CDS             14238..15269
                     /locus_tag="SLE23_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEI8468726.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            15266..16033
                     /locus_tag="SLE23_001826"
     CDS             15266..16033
                     /locus_tag="SLE23_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEI8468727.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            16133..17701
                     /gene="liaX"
                     /locus_tag="SLE23_001827"
     CDS             16133..17701
                     /gene="liaX"
                     /locus_tag="SLE23_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HEI8468728.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            17998..18318
                     /locus_tag="SLE23_001828"
     CDS             17998..18318
                     /locus_tag="SLE23_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEI8468729.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            18318..18668
                     /locus_tag="SLE23_001829"
     CDS             18318..18668
                     /locus_tag="SLE23_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEI8468730.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            18835..19773
                     /locus_tag="SLE23_001830"
     CDS             18835..19773
                     /locus_tag="SLE23_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEI8468731.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            19788..20618
                     /locus_tag="SLE23_001831"
     CDS             19788..20618
                     /locus_tag="SLE23_001831"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEI8468732.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            20662..21687
                     /locus_tag="SLE23_001832"
     CDS             20662..21687
                     /locus_tag="SLE23_001832"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEI8468733.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            21702..22640
                     /gene="galU"
                     /locus_tag="SLE23_001833"
     CDS             21702..22640
                     /gene="galU"
                     /locus_tag="SLE23_001833"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEI8468734.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            22765..23205
                     /locus_tag="SLE23_001834"
     CDS             22765..23205
                     /locus_tag="SLE23_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEI8468735.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            23208..23810
                     /locus_tag="SLE23_001835"
     CDS             23208..23810
                     /locus_tag="SLE23_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEI8468736.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIIIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
BASE COUNT         7934 a         4102 c         5179 g         6617 t
ORIGIN      
        1 cagcgagatt attggtgttt cgaaatacag attacctcag acttgttcag tttgtcgcgc
       61 acaatttcat ttattggaaa caagaggctg ttctggctgt caaaaaccaa tccatttcaa
      121 tctagagagt acgaaaaaga aagtaaattc tatccccgtt tactgcagtg actgtcaaga
      181 atggaagaag aaatatccga cctatgattt tcagcaccgt gccttttttg tgtacgatga
      241 aaatatgaag gcctggctca atcaatacaa gtttatggga gatatccgac tagcaggcac
      301 ctttgcatat aaatggacgc agataaaaaa agaatacccg acatacatct attgtccaat
      361 acctttatct gaaaaaaggc gaacagaaag aggattcaat caagtaagcg agatgttgaa
      421 agcagcaaga attccttttc agatgctact caaaagagag aagcatctgc tggctcaagc
      481 aaaaaacacg cgaaaggaaa gattggagat gcctcaacct tttgaacttg cagtcacctt
      541 ttctaagata caaaataaaa aaatattgat tattgatgat gtctatacaa caggacagac
      601 tcttttccac gcagcagatt gtttgcagat cgcacagccg aaaatcatcc gaactatttc
      661 tttggcgaga tgaattagat gtggaaattt gatagcgatt taatttgcaa ataacctaga
      721 gttcgatata atagaattaa gaagagggaa agagtggtcc ttctccttct tgattgtggt
      781 agacgaaagg ggtaattttt atgtttagat ataatgtacg cggcgaaaat atcgaagtaa
      841 ctgaagcgat tcgcgactac gttgagaaaa aagtaggcaa actagaacgc tatttcagtg
      901 acgcacccga tgcaacggcg catgtgaact taaaagttta tacagaaaaa acagcaaaag
      961 tggaagtaac gatcccatta ccttatcttg tattacgtgc cgaagaaact tctccagatt
     1021 tatacgcaag tatcgatttg gttgttgaca aattggaacg ccaaatccgc aaattcaaaa
     1081 caaaaattaa tcgtaaatcc cgtgaaacgg gcatgaatac tgcaaatgct gctgctttat
     1141 tcaatgaaga ggacgaaaac gaaaatgatt ctgaattaga tatcgtacgt acgaaacgcc
     1201 tttcattgaa accaatggat agtgaagaag cagtcttgca aatgaacatg ctgggacata
     1261 acttctttat ttttgaagat gcagaaacaa atggtacaag tatcgtttac cgccgtaaag
     1321 atggaaaata cggactgatt gaaacagact gatcagcctt acttaaataa caacgaaaac
     1381 ttgcagcagc tactgacagc tgccgcaagt ttttttgagt ttcctcctct tttagatgaa
     1441 atatgaataa attatgaagt tcttacttta atacgcttaa gatatttcaa ttatctataa
     1501 ctaatgataa aatgaaaagt aaagtctaca tagtctggat aatacacaga aggaaaagga
     1561 gattacacaa cgcatggcca atttgattcg ttcacttatc gaaaacgata agaaagaact
     1621 aaaacgttta gatagcattg caaaaaaagt tgaagcatac gctgaccaaa tggcagcatt
     1681 aactgatgaa caattacagg caaaaactgc tgaattcaag ggcagatacc aaaaaggaga
     1741 aacattagat caattacttc cggaagcttt tgcagtcgtc cgagaagcag caaaacgtgt
     1801 attaggttta tatccatacc acgtacaatt gatgggtgga atcgtgcttc acgatggaaa
     1861 tatccctgaa atgcgtactg gtgaaggtaa aaccttgacc gcaacgatgc cagtatatct
     1921 aaatgctctg actggcgaag gggtacacgt agttaccgtc aatgaatatt tagcaacccg
     1981 tgactcgacg gaaatgggcg aactttataa tttcttagga ttaacagtgg ggttgaatat
     2041 caactcaaaa tcttcggatg aaaaacgcga ggcttataat tgtgatatca cttatagtac
     2101 gaataatgaa ttaggatttg actacttgag agacaatatg gtcgtttacc gccatcaaat
     2161 ggtacaacgt ccgctgaatt atgccattgt cgatgaagtt gactcaatct tgattgatga
     2221 agcgagaacg ccgctgatca tttcagggca agcagaaaaa tccacagctt tatatacaag
     2281 agcagacaac ttcgtgaaac gtttgaaaga agaagaagat tataaaatcg atgtacaatc
     2341 aaaaacaatc agtttaaccg aagcagggat cgaaaaagca gaagaaacat tcggtttgga
     2401 taacttatac gacattgaaa atactgcatt gacccatcac ttggatcaag cattgagagc
     2461 caactatatc atgcttttag atatcgatta tgttgtccaa gacggaaaag tactgattgt
     2521 tgaccagttc actggtcgga tcatggatgg acgccgttat tcagatggac ttcaccaagc
     2581 aatcgaagct aaagaaggcg tagagatcga agacgaaacg aaaaccatgg cgacgatcac
     2641 tttccagaac tatttccgta tgtacaagaa acttgcggga atgactggta cagctaaaac
     2701 agaagaagaa gaattcagag aaatttataa catccaagta taccagattc cgacaaatcg
     2761 tccggttatc cgtgatgatc gtccagattt gctttaccca acattacaaa gcaagttcca
     2821 cgctgtcgtg caagatatca aagatcgcta ccgcaaaggt caacctgtgt tagtcggaac
     2881 tgttgcggtt gaaacatctg agttattatc agatatgctg aatcaagaac gtattcctca
     2941 tgaagtgctg aatgcgaaaa atcactttaa agaagcagag atcatcatga atgctggtca
     3001 aaaaggtgct gtgacgattg ctaccaacat ggctggtcgg ggaacagata tcaagttagg
     3061 acttggggta agagaacttg gtggtctagc agttatcggg acagaacgac atgaatctcg
     3121 tcgtatcgat aaccagcttc gaggacgtgc aggacgtcaa ggagaccctg gtatgtcaca
     3181 gttctacttg tcattggaag atgatttgat gaaacgattc ggttcagaac gaatcaaagc
     3241 tttcttagat cggatgaaga tcggtgagga agatgctgtt atccaaagca agatgctgac
     3301 gaaacaagta gaatctgcac aaaaacgtgt agaaggaaat aactatgaca cacgtaaaaa
     3361 cgtcttacaa tacgatgatg tgatgcgtga acaacgtgaa gtaatctata aacagcgaca
     3421 agaagtaatc atggaagaaa aaagcttatc caagccacta atgaacatgg tcaaacggac
     3481 aatcagtcgt gtagtagatg cgcatacaca attagagaaa gaaaactgga atttggaaag
     3541 tatcatcgat tttgccggca gtactcttgt ccatgaagat agtattactc ttgcagatat
     3601 cgaaggaaaa acagctcagg agatcaaaga gtatctaaac gaacgagcac aagaagtatt
     3661 taataccaaa gcggctcaac taaatggtcc agagcaactg ttggaatttg aaaaagtcgt
     3721 gatcttgcgt gttgtggact ctaaatggac agaccatatt gacgcaatgg atcaattacg
     3781 tcagtcaatc ggcttacgtg cttatggaca gaacaatcca ttagtcgaat atcaaacaga
     3841 aggctataag atgtttgaag atatggtagg cgccatcgag tatgaagtca ctcgaatctt
     3901 tatgaaagct gagatccgtc aaaacgtaca gcgtgaacag gtttctcaag gaacagcttc
     3961 tcactcagaa gacggagatg ccaaagaaaa tagtaatact agcgcgaaaa aacagccaat
     4021 ccatgtgaac aaggtcggaa gaaatgatcc ttgtccttgt ggaagcggga aaaaatataa
     4081 gaactgtcat ggaaaaaatg caaactaatt tctgacagca ggattggtga gacaaattct
     4141 ttttttaaga attcgtctca ccttctttct gttatttgct gattctgtta gactagatat
     4201 aatgaaaaaa gtatagtgaa agaaggaaaa aacatggaaa tatccgaaat tcgaaatctc
     4261 ctgacagaaa tgcaggaaaa ggtcacaagt ttcaggaggt ctctttgact tagatcagct
     4321 ggaagaagac atcgcggaag cagaagcaaa aatggctgaa cctggttttt gggatgacag
     4381 cgaagccgca caaaaagtga tcagtgaaaa taacgctaat aaagaaacct atgaccaatt
     4441 ccattctctt gccgaagaac tagaagaaat cgaattgatg gtggagatgc tgcaagaaga
     4501 acctgatgca gcaatgcaag aagaagcaga aacacgtatc aatgcattag atgaaaaaat
     4561 gaagacgtat gaattatcta tgctgttaga cggaccttat gatcgaaaca atgcgatcgt
     4621 cgaattgcat ccaggggctg gcggaacgga gtcccaagac tggggcagca tgcttttacg
     4681 tatgtataca cgttgggcag agcagcatgg ctatcaagta gaaacactag attatcaagc
     4741 aggtgatgaa gcagggatca agagtgtgac cctgctgatt aaaggacata acgcttttgg
     4801 ttatctaaaa tcagaaaaag gtgttcatcg ccttgtacgg atttcgcctt ttgactcagc
     4861 gaaacgacgt catacttctt tttgttcggt agatgtgatg ccagagcttg atgaaacgat
     4921 cgatatagaa atcaatccag atgatttgaa aatcgatacg taccgagcaa gtggtgcagg
     4981 tggtcagcac atcaataaaa cagaatctgc tgtacggatc actcacttgc ctacaggaac
     5041 agtagtagct agtcaggcac aacgctcaca attgaaaaac cgtgagcaag cgatggggat
     5101 gttaaaagct aagctttatc aattagaagt ggaaaagaaa gaacaagaag cagctgcact
     5161 tcgaggagaa caaaaagaaa tcggctgggg ttcacagatc cgttcttatg ttttccatcc
     5221 ctattctatg gtaaaagacc atcggacaaa cgtagagaca ggaaatgtcc aagcagttat
     5281 ggacggtgac cttgatttat ttattgacgg ctatttaaaa atgcatctac aataagaacc
     5341 cattgttaaa ttgaaataaa attgtaagat tttgcaagca tgttgaaaca ttgccatgct
     5401 ataatagcta aagactgaaa aagatatgga gagaacgcca tgattgaaat gaaggatgta
     5461 atgaagaagt actcaaatgg tacgaccgct atccgcaatc tctcgattgt catcgaacaa
     5521 ggagagtttg tctatgtggt tggtccgtct ggagccggta aatctacatt catcaaattg
     5581 atgtatcgag aagaaaaagc ttcaaaagga actttgaacg tcgcaggtca tgatctaata
     5641 gcaatcaaaa accgcgaagt tccttatcta cgcagagaaa tcggcgtggt gttccaagac
     5701 tataaattat taccaagaaa aacagtatat gaaaatgttg cgtacgctat gcaagttatc
     5761 ggcagaaaac ctcgagatat caaaaaacga gtaatggaag tgctggacct tgttggtttg
     5821 aaacacaaag ttcgagtctt tcctagcgaa ttatccggtg gggaacagca acgtgtctct
     5881 attgctcggg caatcgtgaa tacgcctaaa gtacttatcg cggatgaacc gacaggaaat
     5941 ctggatccag aaaactcatg ggaaatcatg aaattattag atcggatcaa tgcccaagga
     6001 actactgtcg tgatggctac acataacagt acgatcgtaa atacgattcg gcaccgagta
     6061 attgctatcg aaaacggccg cattattcga gatcaagcgg aaggggaata tggatacgat
     6121 gattagaacc tttttccgcc atttattaga aagtatcaag agtttgaaac gtaacggctg
     6181 gatgacagtt gcttcagtca gtgcggtaac gatcacgttg actttagtcg gtgtattcat
     6241 ggcagttatc atgaatgcaa ctaaattagc tcaggatata gaaggaaacg ttgatgtatc
     6301 tgtattcgta gatatcggta caaaagacga agagatgaaa aagctagaaa aagaattgaa
     6361 tgacttagat catgttaaaa aagttgaatt ttcaagtaaa gaacaggaat tgaaaaaaat
     6421 ccaaaacgaa atgggtgatt cctggaaatt gtttgaaggt gacaataacc cgttatatga
     6481 tgtgtatgta gtaagtgcta ctgatccttc ttatacaaaa caagtagcag aagaagcagc
     6541 agatttgaag aatgtttctc gttctgatta cggtggagct tcctcagatc ggattttcca
     6601 aatcgctggt gcagttcgga catggggatt agttgcagcg gcattgctgc tgttcgtagc
     6661 gatgtttctc atttcgaaca cgattcggat cacgattttg tctagacagc gtgaaattca
     6721 aatcatgcgt ttagtcggtg caaaaaatgg atatattcgc tggccgtttt tccttgaagg
     6781 tggctggatc ggtctgatcg gtgcgattct tccgattttg atcatcacat ttggttatgc
     6841 atggtttttc caattgatca atccatcatt attacgttcc cattattcat tgattcatcc
     6901 acaaaatatc gtttggaaaa tcaatctttt aatggtcggc attggtgtga tcattggttc
     6961 acttggctcg atcatttcta tgagacgttt cttgaaattc taataccaca atataaataa
     7021 aatgagaaag ttggacagtt tcgttccagc tttctttttt tattggctag gagaatagaa
     7081 ggaagcggct tttttccctt tactttaaaa aacaacttgg gtattcttaa gttggtagag
     7141 gaagaggtga agccgtgaaa attatcgttg acaatttttt tacgatcctt ttgattatga
     7201 atattttgct ttcctttatc atcgtttttc gagaaagaaa ggaaactgct caaacatggg
     7261 catggctgct cgttttgatg ttcattccag ttgtaggatt tattttatat atttttttag
     7321 gaagagggat ttccaaagag aaaatctttg atttgaagat ccaagggaaa atcggtaaga
     7381 acctggaaat tgaagaagac aaacaggcat tgatgcgagg gctttatcct catccgccta
     7441 ctggacaagt agatgtgaaa caattgatct atatgctcac ggtatttgaa agtacgctct
     7501 atacgactaa aaatgaaatc actttattta cagatggtcg tgaaaaattc gatgcgctga
     7561 ttgaagatat caagcaagca gaagaccata tccacttcca gtattatatt tatcgcagtg
     7621 atgcattagg tgaagaagtt cgagatgcat tgacagaggc ggcaagacga ggggtaaaag
     7681 tcagagtcct tcttgatgca tggggttcca cacaagtttc ttccagcttt tttcagaatt
     7741 tgaaaaaagc aggcggagaa atcgcatttt tctttcctct atttgttccg tatattaatc
     7801 ctcggatcaa ttatcgcaat catcgtaaaa tcgtagttat tgatgggaaa atcggatata
     7861 caggtgggtt caatgttgga aatgaatatc taggattggt aaagaaattt ggttattggc
     7921 gagacaatca tttgcgtatt tacggagaag cggtgtatat cttgcaaaac cgttttttga
     7981 tggactggaa ttctcagcat acaaaagaag taggctattc tcccaaattt tttccgtcca
     8041 ttcactctac tggtgatata gctgttcaaa tcgtgacaag cggaccagat accgaacatg
     8101 aacaaatcaa aatgacttat ttgaaaatga tttcgttagc caaacgggag atattgatcc
     8161 aaacgcctta ttacataccg gatggatcga ttcatgaagc actgaagttg gctcttcttt
     8221 caggcgtaaa agttcatatc caaataccta acaaaccaga tcatcttctc gtttactggg
     8281 caacgtattc tttcgctgca gagctgagcg agtatggagc aaggatcgaa acatatgaga
     8341 atggatttat tcatgcaaag acgatgatta tcgatggtgg cattgtttca gttggctcag
     8401 caaatatcga tgttcgttca tttcgcttgg actttgaggt caatacactg atttatgatg
     8461 aacgaatggc ttcacgtgta agaaaagcat tttttgaaga ctcgaaaatt tctacgcatc
     8521 tcacaaaaga aatgtatgaa aaccgaggaa taatcatcaa gatgaaagaa ggattagcaa
     8581 gattgatttc gccgctcctt taaaacacaa aaaggacatg agaaccatca acagatggag
     8641 atctcgtgtc cttttctaac ggggccattt ctgagagtac gtcagaaatg gagaaagcgt
     8701 ctcgcatgag cgaaattaac tttggggtat ctcttgtttt ttggggaaag caagaaataa
     8761 gctaatatat gctattaaaa gagacacatt tcaaagccag tatagcatag aaacttttaa
     8821 tgagatagtt ttttttacaa ttatgaggat ttattttgtt atttaatgat tttgattcgt
     8881 tttcatcaag taatgaaaat gataaaataa acatacttta ggattaaagg agatttctaa
     8941 tgaaaaaact taaattattc ttaccaataa taggattagc tattctttta tcaggctgtt
     9001 caaagtggat tgatcgagga gaatccatta cggctgttgg ctcttctgct ttacagcctt
     9061 tagtagaaac agttgctgaa acttaccaga cagaaaatcc tggaaaattc atcaatgtac
     9121 aagggggcgg aagcggaact ggtttgtctc aagtacagtc aggagcagtc gacatcggaa
     9181 actctgattt gtttgcggaa gaaaaatcgg ggatcgatgc ctcagcatta gtcgatcatc
     9241 gagtagcagt tgttgggatc actcctattg tgaacaagga tattggcgta aaagacatca
     9301 gtatggaaaa cctgaaaaaa ctatttacag gcgagatcaa aaactggagt gaagtcggtg
     9361 gaaaagatca gccagtagtt atattgaacc gtgcttcagg aagcggaacc cgtagcacgt
     9421 ttgaaaaatg ggtattggac ggagaaacag ctgttcaggc acaagaacaa gattcaagcg
     9481 gaatggtgcg ccagatcgtt gccgacacac ccggtgcaat cagctatgtt gctttttctt
     9541 atgtttccga tgatgtagat acgttgaatg ttaacggtgt agaaccgaca gatgaaaatg
     9601 tgacaacgaa caaatggacg atttgggcat atgagcatat gtacacaaga gatcatccaa
     9661 aaaaactgac aaaagaattt ttagactata tcttatctga tgaagtacaa gataacatcg
     9721 ttggagaact aggttatatc cctgtttctc atatgaaagt cgaacgtgat tggcaaggaa
     9781 atatcgttaa agagtaatct ttacacaaaa tttacaaact tagctaaact tttacatgtt
     9841 attaaaacca aattgatgtt caatttgtac actgagtgag tatgttaaac ctgattaagg
     9901 gggagtcatc tgtggaagat gtgaaaaaag tattattaac aaaatcaaaa cgttcaaaaa
     9961 tggaacagcg tggaaaattc atcagttttt tatgtatcgc gctgatcgtg ttggttgtat
    10021 tatctatttt ttattttgta gctagtaaag gattggccac cttttttact gataagatca
    10081 atgtatttga ttttctgttt ggtacagatt ggaatccaag ccaaatcgga gcaaatggga
    10141 aaccaatggt aggggcattg cctatgatca caggttcgtt tattgtgacc tttttatctg
    10201 ctattgttgc cacaccattt gccattggtg cagcagtatt catgacggag atctctccta
    10261 aaaacggaac gaagatctta cagccggtca tcgagctgct tgtaggtatt ccttctgtcg
    10321 tttatggttt tatcggttta tcagttatcg tgccttttgt cagaagtatt tttggcggga
    10381 cagggtttgg tatcttagct ggtacatttg tgttgttcgt tatgatcttg ccgactgtca
    10441 caacgatgac tgttgatgca ttaaaggcag taccacggca ctatcgggaa gcttcattag
    10501 cgcttggtgc cacaagatgg caaacaatct acaaagtcgt gctacgagca gccgtgcccg
    10561 ggattttaac agcagtcgtt tttggtatgg ctcgtgcgtt tggtgaagcc ttagctatcc
    10621 aaatggtcat cggtaatgca gcattgatgc caacaggact tactactcct gcttctacat
    10681 tgacgtccat cttaacaatg ggaatcggaa atacaatcat gggaacagtt gaaaataatg
    10741 tgttatggtc attagcgctg atcttgctat tgatgtcatt attctttaat atcgtgatcc
    10801 gtatgattgg gaagaaagga gagctgaaat aatgaacgca aaacgctcag ataaaattgc
    10861 tacaggtgtt ttatatgtag tttcggggat catcgtattg attttagcag ctttactact
    10921 ttatatctta gttcggggaa taccgcacat ttcatggtcc ttcttgaccg aaccttccaa
    10981 agcctaccaa gaaggcggtg gaatcgggat ccagctattt aactcgattt atttgctttt
    11041 gatcacgatg atcatcagtt ttcctatttc tttaggtgcg ggtatctatc tttcagaata
    11101 tgctggaaaa aactggctga cagatgtgat tcgcacgtcg attgaaatct tgagctcatt
    11161 gccttctgtc gttgtcggtt tattcggttt cttggttttc gttattcaat tccagtatgg
    11221 tttctcgatt atttctggtg cattggcttt gactgtattc aacttgcctc ttttgactag
    11281 aacagttgag gagtctttac aagcggtcca ttacacacaa cgagaagcag gattggcttt
    11341 aggtttgtca cgctgggaaa cagtgataaa agtggtggtt ccagaagcga caccagggat
    11401 tttgactggt gtgatcctaa gttctggaag aatttttggt gaagcagctg cattgatcta
    11461 tacggctgga caaagtgcac ctgcgttaga ttttacgaac tggaatccat taagtgtttc
    11521 aagcccgatc agcattttcc gtcaagctga aacattagct gtccatattt ggaagatcaa
    11581 tacagaaggc acgatgcctg atggtgtttc tgtttcggct ggcgcttctg cagtgttgat
    11641 cattgctgtt ttactgttca acttcggcgc tcgtgcgatt ggcaaacgat tataccgaaa
    11701 aatgacttca gcctaaggag aagaagcaaa atgaaaaaat ataactggaa tgaaacaaat
    11761 gtcatcacca tgccaaaaga gaaagaagta gcactatata cggatgatct acatgtctgg
    11821 tatggcgaca atgaagcaat caaaggagtg gatctggaat ttgaaaaaaa taagatcact
    11881 gcactgattg gtccttccgg ctgcggaaaa tctacgtatc ttcgttcgtt gaatcgaatg
    11941 aatgatggga tcgctaatac gaaaatcact gggaaaatca tgtatcaagg cgtagatatt
    12001 aatgcgcctc aagtggatgt ttatgagatg cgcaaacgga ttggcatggt ttttcaacgt
    12061 cctaatccgt tcagcaagtc gatttatgac aatattacat ttgctttgaa acagcacggc
    12121 gaaaaaaaca aaaagaaatt agatgaaatc gttgaaacaa gcttgaaaca agctgccttg
    12181 tgggaccaag taaaagacag cttggacaaa agtgccttgg ctttatctgg cgggcaacag
    12241 caacgtttat gtattgctcg tgcgatcgcg atgaaacctg atatcttgct gctagacgag
    12301 ccggcaagtg ctttggaccc tatttcgaca ggaacggttg aagaaacact tgtaaacttg
    12361 aaagaagact atacgatcat catcgtgacg cataacatgc aacaagcggc tcgtatcagc
    12421 gactatactg cctttttcta tctaggaaaa gtaatggaat atgacaaaac taacaagata
    12481 tttaccagac caaaaattca ggcaaccgaa gattatgtgt ccggtcattt tggttaagac
    12541 ggaggcctca acatgacaaa agaaattatt tcatctaaag atcttcatct gtattatgga
    12601 aagaaagaag cactaaaagg gatcgatcta agtttcaatc aaggggaaat cactgcgatg
    12661 atcggtcctt ctggttgcgg gaaatccact tatctgcgtt ctttgaaccg gatgaatgac
    12721 ctgattccga atgtaacgat caccgggagt gttttatata aagacaaaga catctatggt
    12781 ccaaaaacag atgttgttga actaagaaaa gaaatcggca tggtattcca gcagccaaac
    12841 ccatttcctt tttctatcta tgaaaatgtc atctatggat tgaaattaaa aggggaaaaa
    12901 gataaaaaag tccttgatca agtagttgaa gaaagcctga aggcagcgtc tgtttgggat
    12961 gatgtgaaag acaaattgca taaaagtgct ttatctttat ccggtgggca gcagcagcgt
    13021 gtatgtatcg cacgtgtttt ggcagttaat ccggaaatca tcttattgga tgaaccaaca
    13081 agtgcgcttg atcctgtttc tactgggaaa atcgaaagta tgctgttaga attaagagag
    13141 cggtatacga tgatcatcgt gacccataat atgtctcaag cttcacgtat ttcagataag
    13201 acggcattct ttttagatgg tcacttgatc gaatacaatg atacgaagaa gatattcatg
    13261 aatccagaaa aacaagagac agaagattat atttcaggtc gatttggata aggaggaaac
    13321 ggaatgctac gtacacaatt tgaagaagaa ttgctgaatc tccataatca gttctacgaa
    13381 atggggatga tggtgagcag cgccgtgcac aagtcagttc gtgcatacat caaacacgat
    13441 aaaatcttag cccaagaagt tatcgaaaac gatataaata tcaataacat ggaaacacgc
    13501 ttggagaaga aaagttttga aatgatcgca ttgcaacagc cagttacaac tgatttgcgt
    13561 atgatcatta cggtcatgaa agctagctcg gatttagaac gtatggccga tcatgcggtg
    13621 tctgttgcta aatccacgat tcgcgtaaaa gggcagacga gaataccgga aatcgaaaaa
    13681 gagatctccg atatgtccga ttatgtgaaa aaaatggtgg acaacgtcct agttgcttat
    13741 gtcaaaacag acgaaaaaga cgcacgtacg atcgccaata tggatcaaag agtcaatgac
    13801 tatttcaatc gaatctataa tgcaacaatc aaaaatatgc aggaaaatcc tgagacagtc
    13861 atcagtggaa cagactactt gaatgttgcc agttatctag aacggatcgg agactatgtg
    13921 acaaacatct gtgaatggat cgtctacttg gctacaggga aaatcactga gttaaatacg
    13981 aaccacaatg agattttcta aactaaagcg gtgattctgc cgtttgttta ggaaaagagg
    14041 ttgtgaaatc agcggttgtg aaaaagctgt tctgcatcaa gtaataagaa cagtcaaaca
    14101 aaaatagctc ctcatatttt tcatttggct ggacttatta ccgcagatgc aagcttttga
    14161 acactgttta ttcgggaaag ggtttgtgac aaaatatgtc acaaaccctt ttcatcattt
    14221 catagaaagg ataaagaatg caaaaaaaaa ttagcatcat cactatattt tttatttgtg
    14281 tgcttacttc atgggttatt cagcatcaag ctgctttata tgaagtacct gtcatcgaga
    14341 tcgaaaaagt acgaataaaa gaggatcatc aattgattac aggaagactg atgaacacga
    14401 atcaaaaagg agaatcgatt tatttatcgg ttccttatca aaaaaatcaa atagaaacag
    14461 caaatataaa agcgagacaa atgtatctag tccaaatgca tggagatgaa tggcagctag
    14521 tagcaaaaaa aaatgatggc tggcttttct tcttcacaag tatcttcatt ggcgccatgt
    14581 tgcttattgg cggaaaacat ggtctatttg ctttaggaag tctcatcatc aatatcgttt
    14641 tacttttact tttgttgctc atctttacta aaatagaagg gatttctcta ttaaatatat
    14701 ctatcctgtt cgtcgttata gggatgatta ttagcatatt ggctttagat ggatggaata
    14761 gaagcagtat aatcaaaatt tcagctgcag ttacgagtgt ttttttagca ttttttattt
    14821 gtcttttgac aatgaatctt tggaaagacc aaggactgcg ctatgaggaa ctgaattatc
    14881 tgacacgacc gtatcgttct gtttttcttt ctagcgtact gattggaaca gctggaggaa
    14941 cactcgatac cgttatcaca gtcattgcga cattagaaga attgactaag cgacaaccag
    15001 aaataacagc gaaacagtta tggctttcgg gaaggcaagt gggtcgagat gtgattggct
    15061 cgatgaccaa tatccttttg ttcgtctata tcagtgggtc agttccatcg cttcttttat
    15121 atttaggaaa tcaatggtcg ttcaaagaaa cgatagaaca gcatttatca ttggaatttt
    15181 tacgcgtcat tgctggcagc ttaggaatag tattatcgat ccctatctcg gtcctctttt
    15241 ttctgactgt aaggaggctg aaacgatgaa tgtacttatt atacttgttg ggattttagc
    15301 aatcagcgtg ctacttattg gcggtacgca aggtatgtat attcttttag gcttattcat
    15361 caatttaggg atctttttct tgttgttatt cggttatcat cagaagtggc cgatactggc
    15421 attgtcggtc ataggatttt tattgattgc tgtggttatc ttatttttta tcaacggtta
    15481 taatctaaaa atgcgtgcag cttttgtgag tatactgatc tttttatttt gtttcctact
    15541 attgcttcct atcactgatt ttttagcaat ccaaggtttt acaacgatag aactagaaga
    15601 attatctggc ttagataaga ctttagcgat tgattttaga ttacttacga gatcgttgct
    15661 tctgattagt cttagtggtg ctgttttaga tgcgagtgta gcaatttcta gtgggacatt
    15721 cgaagtatat caggcaaatc cgcaattatc tttttaccaa ttgcgccatt ctagtttcgc
    15781 tattgctaaa aaaatattgg cgtcaacagt aatgacactt ctttttgcat tcatgggaag
    15841 ttctttagcg ttgatcctct ggtttattga tttagacatt ccttttcagc aagtgatcaa
    15901 tgaaaaatca tttgttctag aatatacgat ggctattctt accacattgt ccgcactact
    15961 tgttcttcct ttaacctgcg tgactacagc atatctcttt acaaaaaaga aagaacaact
    16021 caagatggag taaaagttac aacttaagtc ctatgacatt tttactgaat cagtgcataa
    16081 tatggatgta aggaaaagct tgcaaacaat tttgcttaag gaggcaattt ccatgaaaga
    16141 aagagaacgt attttagatt tagtgaaaaa aggaatcctt tcgactgaag aaggcttaga
    16201 tttattagaa agcatggcaa ctgaaaaaga cgaaaagcaa atcaaaaaag aagcagacaa
    16261 ggtaactgct agtcataaag aaaaagatca ggcaagtcaa ttgatcgata aacttgaaaa
    16321 cggcgaagaa gaaatttctg agccagttga tccaaaggaa agagaaagac aagatcaaga
    16381 aaacttagaa aagatcttag atgaactagc aactgaagcg aataaaactt cggcgcgtct
    16441 agatgaagta aatgctcaat tcgctgacaa taaggcagca cgcaatgaga aacaggaagc
    16501 attgatgcag ctgaatacaa aagaagaatt aggcgagttg acagaagaag aattagcaca
    16561 gcgtcagacg ttagaagcag aaatcaaaga gttagaagct agtggcgata cactgttaga
    16621 agaacaattg aaattagaag cagaattaaa agatatccgt aagaatcaat ggtctgagaa
    16681 aaaagaaacg tttactgata agtttgaatt gccagatgat tggaaagatc aagcaacaga
    16741 tacactgaat caagtaggcg aaaaaatgtc agaagctgga tcacagttag gaaaattctt
    16801 gaagaaaaca ttccaaactg tttcagaaac agtgaatgac aacatggaat ggaaagatgt
    16861 cagcttgcgt gtccctggga ttgcgacaac gaaatttgag catgaatttt actatgaagc
    16921 tcctgcagca agtatccttg atatcaaggc agcaaacgga aacgtgacgt taaaaacgtg
    16981 ggacagcaac gatgtgaaag ttgaagctaa gatcaaactt tacggaaaaa tgggtgctga
    17041 accatttgaa gcattctctg aacggagcca gattgaggtt aatgaagatc atatctcctt
    17101 ccaaattcca aataaacgtg tgcgtgcaga ccttgttttc tacttaccta aacgagtata
    17161 cgaccacgca gctattaaac ttctaaatgg caacatcatg attgaaacat tggaagctaa
    17221 agatatttat acaaaatcta cgaatggtaa catcatcgtg gaccaattaa ctgcaacgat
    17281 gctggaagta gaaggtgtaa acggcaatat cgatattcga aacgggaaca tcttagattc
    17341 tattatcgaa acagtaaatg gtacagtgac atttggtgcg acagcagaaa acctttctgt
    17401 gtctttggta aatggtgatg tacgtcttac gattaaagaa gataatttga aaaaagtaga
    17461 agcaagttca gtgaacggaa atgtcaaagt cgctttacca gatggcatcg gtttggaagg
    17521 acatgctaaa acaagtcttg gaagtatcaa cagccgtctg tccaattacg aagtagttcg
    17581 tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt cgtgtttcag atggtgaaat
    17641 cgcgcaagtg caactttcaa cgacaacagg aagtatctat ttaaaagata cagataaata
    17701 aagaggttgt gaaagagatg ttcagccttg agcaataaga agcgattttg taaaatagct
    17761 tcccctattt tacaaaattg tgccttattg ccgataggct atctcttgaa caccgtttac
    17821 caagagatta tgaacttgcc aattatcgcc gagtcacaag gaataatttc aaaaaaagct
    17881 cgtcacgttt tatgaatatg gtaatttgtg accgagaatt ttgcaaaaag acaccgatta
    17941 agaagaaggt tgtcacaacg attttcttca tttaaaatag tagaacagag gtgagacatg
    18001 atgaaaaaaa agttgacaaa atccaataaa aatgttgttt tgacagggac tttagcagga
    18061 ataggagaat acatcgggat tgatccgact gttatccgtg tgctttatgt attcctgagc
    18121 ttagttgctt ttggaagtcc aatcatttta tacattttat tagctttgat tatcccatct
    18181 gcgcgttctg cacgaacaaa ctatggacat aacaatgcat attatgaaaa aaacaattat
    18241 cgtgaacaaa ctcgtgaaca aacaaaaaaa cgcaaagaag cggaaaaaat cgatgatgac
    18301 gaatggagtg acttttaatg tcgtactttc aacgtatttt agttaatacg ttaacattca
    18361 tatcattggc tgttcttttt cctgcgatgg tccatgtgag cagtatttgg acggccgttc
    18421 ttgccagctt cgtattgtct gtgttgaata tgtttgtcaa accgattttg acgatactgt
    18481 ccctgccctt tacattagtc acattgggat tgtttacgtt tgttatcaat gcagcgattc
    18541 ttaaaatgac ctcctttttt gtgggagcag aacattttag tttttcttca ttcggtgcag
    18601 cgttgttagt agctatcttg atgtcgcttg tcaatgtaat tgtcagcgaa cataacagta
    18661 gaaaataaaa gaaagctgtg ccgaactatc ggcgcagttt ttttatttag aatcaggaat
    18721 gcgttttcta ttacattggt aattaaataa aaacgttttt tttaattggt agtacttttg
    18781 gctagacaat gataaaatga tagagaacac tctaatagaa atgaggtagc atgaatgtca
    18841 gaagttgtaa aagttagcca attagtgaaa aaattatctt tggaaatcgt gacaggcgac
    18901 gagaaaagct tagaccgtgt catcgtaact ggggacatct cacgcccagg actagagttg
    18961 actggttatt ttaattatta ttcccataat cgtttacagc tatttggcag taaagaaatc
    19021 agttttgcgg aacggatgat cccagaagag cgtttgatca tcatgagaag attatgtagt
    19081 gaagatatgc ccgcatttat tatttcaaga ggattaccag ctccagaaga aatgatccag
    19141 gcagcaaatg aaaatgggat agctgtactg cgttctccca tctcaacttc tcgcttatta
    19201 ggagaattat ccagttattt agatggtcgc cttgcccctc gaacaagtgt ccacggtgtt
    19261 ttagtggatg tttacggatt aggtgtactg attcaaggtg acagtgggat aggaaaaagt
    19321 gaaacagcgt tggagttgat caaacgcggt catcgattga tcgcagacga tcgagtagat
    19381 gtttatcagc aagatgaatt aacggtgatc ggagaaccgc ctaaaatcct ggaacatctg
    19441 attgaaatcc gaggaatcgg gatcattgat gtaatgaatc tttttggtgc gagtgcggta
    19501 cgtggctcta tgcaagtcca gttggctgtt tatctggaag catgggcaaa agataagaaa
    19561 tacgaccgtc tgggctctga agacacgacc gttgaaatcg cggaagtagg cattccacaa
    19621 ataaaaatcc ctgtcaaaac aggacgaaac gttgcaatca tcattgaagt agccgcgatg
    19681 aatttccgtg cacgtacaat gggctttgac gcaacgaaaa catttgaaga aagattaagt
    19741 cgcttgattg aagaaaactc aggcaacgac tagcaaggag tgacaatatg ttagcacaaa
    19801 tcaatcgagt tgcttttgag cttgtaggga ttcctatcta ctggtatgca ttgatcatcg
    19861 tatcaggtat cattatcgcc atgtggctta gcagcagaga ggctgttcgg gtaggattaa
    19921 aagcagatga tgtgacagat tttatgttgt ggggattgcc tatctccatt attggcgctc
    19981 gcttatatta tgttttattt gatcttcccc agtatatagc tgatccaatc caaatattca
    20041 atatccgttc aggaggctta gctatttatg gcggactgat tgcaggcgcg atcacgctgt
    20101 atttttttac taaatatcat tttatttctt tgtggacttt tttagatatc gctgcaccaa
    20161 gtgtattatt agcacaagca atcggtcgtt ggggaaattt catgaaccac gaagcatatg
    20221 gaccagacac gacgcgaagc ttcttagaaa gtctgcattt accgcaattc atcattgata
    20281 atatgtatat cgaagggatc tatcgtcaac caacatttct ttatgaatca ctttggagtt
    20341 tgattggatt tattttgctt ttgtttttac gaaagaaacc acaccttttg aaaaaaggtg
    20401 aagtcctttt atgttatcta atgtggtata gtttcgggcg tttctttatt gaaggattac
    20461 gtacagacag tctttacttt ttaggtgtga tccgtatttc tcaattatta tctgctgtgt
    20521 tatttgtcgg tacattgatt ctatttattt ggcgcagaaa aaaaggaaat ttaccggatt
    20581 atgaccgctc attaggaaaa aatcaacaaa ttatctgatt tttagagcgt taaaaatgaa
    20641 aaaaatttca ggagtggtaa aatgaattat agagtagcgg ttttaggacc aggctcttgg
    20701 ggtactgctt tggcacaagt cctcgccgaa aacggacatg acgttcggat ttggggacat
    20761 cgtgcttcac aagtagaaga aatcaacacc caacacacga atcaacgtta tttaccagat
    20821 cattgtctac ccgattccat ccaagcattc accaatatgg aagatgcagt aaaagacgca
    20881 gatgcggtgc tattcgtcat tccaacgaaa gcaatacgtt ctgttgcaaa agaactagtg
    20941 cctaaattga atacaaagcc agtgatcatc catgcaagta aaggattaga acaggggaca
    21001 cataaaagga tctctgacat cttgttagag gaaatcccag tagaaaaaag aaaagctgtt
    21061 gttgttcttt ctggaccaag ccatgcagaa gaagtagcga aacatgacat cactacgatc
    21121 acagctgcaa gtacagatgc aaaagcagca aaatatgtac aagagctgtt catgaataat
    21181 tattttcgga tctataccaa tcctgatgtg atcggtgtag agatgggggc agctttgaaa
    21241 aatattattg ctattggtgc tggcgctatt cacggcttag ggtttggcga taatgcaaag
    21301 gcagcaatca tgacgcgcgg attagctgag atcagccgtt taggtgtagc aatgggtgcc
    21361 aacccgctga cctttatcgg attaagcgga gtaggcgatc tagtcgttac ttgcacaagt
    21421 gttcattcta ggaactggcg cgcaggcaac ttgttaggac aagggcagcc cctagaagag
    21481 gtgctagcca atatgggaat ggtcgttgaa ggtgtgaata ctacccaagc agcgatggaa
    21541 ctagcccaaa taatggaaat cgaaatgccc atcactcaaa caatctatga agtgctgtat
    21601 gaacaaaaag aaatcaaaac agccgcaaaa gaaatcatgt tacgtgatgg gaaaaaagaa
    21661 aatgaattct cattaacaat tttttgaagg agcgaatgta tatgaaagtc aaaaaagcag
    21721 ttattccagc agcaggatta ggaacaagat ttttaccagc aacaaaagct atggcaaagg
    21781 aaatgttgcc aattgttgat aaaccaacaa tccagttcat cgttgaagaa gcgttgaaat
    21841 caggtatcga agacatcttg atcgttacag gaaaagctaa acgaccaatc gaagatcact
    21901 ttgattcaaa tattgaatta gaaacaaacc taagtgaaaa aggaaagacc gaattattga
    21961 aattagtaga agaaacgaca gatgtcaact tgcatttcat ccgtcaatct catccaaagg
    22021 gtttaggaca tgccgttctt caagcaagag cctttattgg aaatgaacca tttgtcgtta
    22081 tgctaggcga tgatataatg gaagacgaag taccattgac acagcaatta atcgatgatt
    22141 acgaacgtac tcatgcttct acgatcgccg ttatgcaagt tcctcatgat gaaacttcaa
    22201 aatacggaat tatcaatcca ggagaagtat tggaagatgg gttatacaat gtcaaaaact
    22261 ttgttgaaaa accagatcca agcaaagcac caagtgattt agctattatt ggacgttact
    22321 tattgactcc agaaattttt gatgtattgt ccgagcaaca accaggagcc ggaaatgaaa
    22381 tccaactaac tgacgcaatc gatacattga ataaaacaca acgcgtattt gcccgtaaat
    22441 tcacaggtaa acgttacgat gtcggtgaca aatttggttt tatgaaaaca agtattgaat
    22501 atggtctaac acatccagaa gtaggtgcac ctttacgtga gtacatcctg tctttaggta
    22561 aaacattaga agcagaagga agcaagatcg atcataatcc aaaaggaata acagaaatca
    22621 aagaagaaaa gaaaaaataa cccttttttc taacgagctt cagctgctaa ttgaataaaa
    22681 agtagttgaa gctcgttttt atttgtttaa aaaacacgaa aatgctatcc ttatagaaaa
    22741 gagagacaag aagggagttt gatcatgtca ggaggagaaa ttgcaggatt gatcgcagca
    22801 atcgcctttg cgatacttgt cgtttttatc gttcgtgtgt tgttgcaagt ttctaaaact
    22861 ttagaaaaag tagatcagac tgtagcagaa gcaaatacga cgatcgaaat cgtcacaaaa
    22921 gacgtagatc ttttgtctag acaagtagaa ggcttactgg tcaaaagtaa tgaactgctc
    22981 ttggatatca atggaaaagt cgcaacgatc gatccattgt tcacagcagt tgctgattta
    23041 agtgaaagtg tatcagaact taatcattct agtaaaaaca tcgcgacgaa agtcggcgga
    23101 atcggtaaaa cgacagctaa agcgacggtt gccggaaaag tcggtgggac agcgatgaaa
    23161 ttttttaaaa acaaaaaaca tactgaaacg acaggaggaa aataaaaatg gctaaaaaag
    23221 gtggattttt attaggtgca gtagtcggag gcacagccgc agcaatcgcc gcgttattgt
    23281 tagcaccaaa atctggtaaa gaacttcggg atgaattagc tgcccaagcg gatgatttga
    23341 tggatatggc ttcagattac acagatatgg cgaaagaaaa atcgactgag ttaacaggta
    23401 ttgcaaaaga aaaagcgcaa gatctttctc aacaagcagg tgatctagca ggtagtgtca
    23461 aacaaaaagt aagtgaatca gcagatgaag caggaagtga atctgacgat atcttgttaa
    23521 atcttaaaga acaatcagct gacttatcta atcgtttcaa aaaaacggca gaagatatga
    23581 aaaaacctgc agatgaatta ggaagtattg ctaaagatac ttcagaagat atcataattg
    23641 atgtaaaaga cgctgctggt aaagcaggag atactgtcaa tgaaggaatg tcagaagcaa
    23701 aaccagttgc agatgactca aaagaaatga tgaaaatggc aaaagaagat gcgaaagaag
    23761 ctaaaaaaga aataaaagat acaatgacag attcatctac aaatcactaa aatcacaaat
    23821 ttatagaata aa
//
LOCUS       DARPZJ010000038        23576 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.039, whole genome shotgun sequence.
ACCESSION   DARPZJ010000038 DARPZJ010000000
VERSION     DARPZJ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.039"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            43..675
                     /locus_tag="SLE23_001836"
     CDS             43..675
                     /locus_tag="SLE23_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEI8468737.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(677..1582)
                     /locus_tag="SLE23_001837"
     CDS             complement(677..1582)
                     /locus_tag="SLE23_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEI8468738.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1667..2326)
                     /locus_tag="SLE23_001838"
     CDS             complement(1667..2326)
                     /locus_tag="SLE23_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEI8468739.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            2642..3586
                     /gene="mvk"
                     /locus_tag="SLE23_001839"
     CDS             2642..3586
                     /gene="mvk"
                     /locus_tag="SLE23_001839"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEI8468740.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3579..4556
                     /gene="mvaD"
                     /locus_tag="SLE23_001840"
     CDS             3579..4556
                     /gene="mvaD"
                     /locus_tag="SLE23_001840"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEI8468741.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4569..5654
                     /locus_tag="SLE23_001841"
     CDS             4569..5654
                     /locus_tag="SLE23_001841"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEI8468742.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5651..6715
                     /locus_tag="SLE23_001842"
     CDS             5651..6715
                     /locus_tag="SLE23_001842"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEI8468743.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6964..7767)
                     /locus_tag="SLE23_001843"
     CDS             complement(6964..7767)
                     /locus_tag="SLE23_001843"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEI8468744.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7787..8629)
                     /gene="kduI"
                     /locus_tag="SLE23_001844"
     CDS             complement(7787..8629)
                     /gene="kduI"
                     /locus_tag="SLE23_001844"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HEI8468745.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(8645..9652)
                     /locus_tag="SLE23_001845"
     CDS             complement(8645..9652)
                     /locus_tag="SLE23_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEI8468746.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(9659..10303)
                     /locus_tag="SLE23_001846"
     CDS             complement(9659..10303)
                     /locus_tag="SLE23_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEI8468747.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(10403..11161)
                     /locus_tag="SLE23_001847"
     CDS             complement(10403..11161)
                     /locus_tag="SLE23_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HEI8468748.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(11288..12439)
                     /gene="fucO"
                     /locus_tag="SLE23_001848"
     CDS             complement(11288..12439)
                     /gene="fucO"
                     /locus_tag="SLE23_001848"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HEI8468749.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(12521..12832)
                     /gene="rhaM"
                     /locus_tag="SLE23_001849"
     CDS             complement(12521..12832)
                     /gene="rhaM"
                     /locus_tag="SLE23_001849"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HEI8468750.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(12834..13679)
                     /gene="rhaD"
                     /locus_tag="SLE23_001850"
     CDS             complement(12834..13679)
                     /gene="rhaD"
                     /locus_tag="SLE23_001850"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HEI8468751.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(13693..14949)
                     /gene="rhaA"
                     /locus_tag="SLE23_001851"
     CDS             complement(13693..14949)
                     /gene="rhaA"
                     /locus_tag="SLE23_001851"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HEI8468752.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(14946..16406)
                     /gene="rhaB"
                     /locus_tag="SLE23_001852"
     CDS             complement(14946..16406)
                     /gene="rhaB"
                     /locus_tag="SLE23_001852"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEI8468753.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            16559..17428
                     /locus_tag="SLE23_001853"
     CDS             16559..17428
                     /locus_tag="SLE23_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HEI8468754.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(17554..18453)
                     /locus_tag="SLE23_001854"
     CDS             complement(17554..18453)
                     /locus_tag="SLE23_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468755.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(18618..19442)
                     /locus_tag="SLE23_001855"
     CDS             complement(18618..19442)
                     /locus_tag="SLE23_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEI8468756.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(19453..20748)
                     /locus_tag="SLE23_001856"
     CDS             complement(19453..20748)
                     /locus_tag="SLE23_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HEI8468757.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(20764..21243)
                     /locus_tag="SLE23_001857"
     CDS             complement(20764..21243)
                     /locus_tag="SLE23_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HEI8468758.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(21249..22277)
                     /locus_tag="SLE23_001858"
     CDS             complement(21249..22277)
                     /locus_tag="SLE23_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HEI8468759.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(22294..23400)
                     /locus_tag="SLE23_001859"
     CDS             complement(22294..23400)
                     /locus_tag="SLE23_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEI8468760.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
BASE COUNT         6779 a         5200 c         4239 g         7358 t
ORIGIN      
        1 cccgcttctt tgctatacta aagaaaaacg aggtgaaccc acatgaaaaa aatcgaacct
       61 attccacctt ctcttcctct tcttacaaag ggagagtttt atttagaaga tgaggagatc
      121 ttctctggtc ttctgatcaa cgggggtgac caaagctatc tcgatgccaa aaatatggta
      181 ttaagagaga gtcatatcca aaaacttacg atgcaaaaaa cagttttacg tcattttgaa
      241 tgcagtaatg tcatttttga aaaatgtgat ttttccaatc tggagtggat tggtggcagt
      301 ttccaccaag tcgtgtttca tcaatgtaaa ttaacaggta cgaattttgc cgaaagttat
      361 cttcgagact gtactttcac tgattgtatt gcttcgatgg cttcctttag tagtacaaac
      421 ttgaaagctg tctccttcga tcattgtcaa ttagaagaca gcgaatttta tgaggtcact
      481 tggaaaaacc tttttttgtc tgacaatcag ttgaccggtt cgaactggtt tcgaacttct
      541 ctgaagggat tagactttac gactaatttc ttcacagcaa tcgctttatc tcaagattct
      601 ttggcgggac taatcgtcaa ccaagagcaa gcacttgtga tcgcccaagc ccttggtttg
      661 cagatcaaag actagatcaa cgaatccgcc gccacagtgc aataagcatc caaatagata
      721 agaccaaact gatgatcaag gcgattcccc atccgaaaac ggaatgggta aagggtaact
      781 ggagattcat tccgaagaat cctgtcacaa tagttggaac ggtcaagatc agcgaccaga
      841 ccgtcaaaaa tttcatcgtg tcattcaagt tgttattcag caaattatta taagtgccag
      901 agagctggtc taaaatctgc gaagctaagt tcgtcatttc aactgcttgt cgtgcttcga
      961 tcagcgcatc gtccaactct tctttttcct tttctgacaa cttgcgataa atagccaatg
     1021 ccttgatttg ttctaaaagt actacatttt gttttgttcc tgtaactaag taaaccaaac
     1081 cgatctctaa atctgaaagt tgcagcagat tcttgttcgt tgttttttct cttaatttca
     1141 gattaagccg ctgacgttca ctattcactt cctcgattaa aggaaaaaag gaatcagaaa
     1201 tcaaaaacaa tgtacgaaac aataaactgt atacactcat gtctggcatt cgttccaaaa
     1261 gcgatcgaat tagtcgaatc acgtactcgg tattcggcgt ggtaaatgta aacaaaccgt
     1321 cttcttttaa aataaaagcg ataggactag tttcataatg attatcgact ttttgctggt
     1381 gcggaacatt tgatacaagc agtaacgctt catcaaaaga atcgtactct acgcgcgccc
     1441 gttcattttt atctagagaa taagtcagca tctcgtcact aatgccatat tcttctttta
     1501 agtttttaac agctagcaca tcgttttgct gtacattgat ccaaaaatta cggtcttgat
     1561 taaaatagtg tttttcccgc atactctatc ctcctgacat ttgtttccag tataaagaaa
     1621 aaagtcgctc aaataaaggt ttacccttta tttgagcaac tgtaaatcaa atggctactt
     1681 tggtttggcg aatctctgct aatttttctt cgatcatttt caagacttct tcttttgctt
     1741 gaggatcttc cacaaaatta tagcggtctc catcgatttg gatttttgga ctttctttgt
     1801 attcttcata ccattgatcg taacgtctgt tcaattcttt gtaataatcg tatagacttg
     1861 gatcaaagga caattgttca tacgaacgac cacgtttttc gatacgctcc aacatcgtat
     1921 caaaagatac acgaatatga actaataaat ccggatgttt tttatgggca gcatagggaa
     1981 gttcttccat catgttttcc agcagttcat catacacacg aacttctgtt tctgttgctc
     2041 ttcctagatc tgcatttaga tggaaaagca gtgaatcttc ataaatcgaa cggtccaata
     2101 cattattgtc atctttcatt gcttgtttga tgcttgcaaa acgtttattc aaaaaataaa
     2161 tttgcagcaa aaaagcatac tgttcagggt ttgcataaaa taagggcaag acttcattat
     2221 catcaatcga ttcataaaat gcctgactat caaagtgttc agccatcatt tctgttaaac
     2281 ttgattttcc ggcaccaatt gtacctgcta aaacgatcac gctcatttac ctccagctca
     2341 cttcatcact aaatattgtg tttaactcca acctttttaa atataccccc aatatctagt
     2401 agtgtcaatt gtattttttt ctagtcaaag aagaaaaaaa gtcaaaaaat tcttaagaaa
     2461 aaagtgtttt ttctttagaa aacgtattct tagttttact tctgagatgg ttttagtaaa
     2521 ataaaggagg aatgtttttt gagaccctta gtggacaaaa aaattcgtga agcagcgcaa
     2581 ctcgttttgg gcgctttatt ttttgcttaa aaatcacttt tacgtgagaa ggagttagat
     2641 tatggcaaac tatggccaag gagaatcaag cggaaagatc atattgatgg gcgagcacgc
     2701 ggttgtttat ggagaaccag cgattgcctt tcctttctat gcaacaaaag tcaccgcatt
     2761 ccttgaagag ctggatgcaa tggacgatca actggtttct tcctactatt caggaaattt
     2821 agccgaagct cctcatgcat taaaaaatat caaaaaatta ttcattcact taaaaaaaca
     2881 gcatgacatc caaaaaaact tgcaactgac cattgaaagc acgattcctg ctgaacgtgg
     2941 aatgggatca agcgctgcag tcgccacagc agtcactcgt gctttttatg attacttagc
     3001 atttcctttg tctcgtgaaa tactattaga aaatgtccag ctttcggaaa aaatcgccca
     3061 cggtaatcct agtggaatcg atgcagccgc tactagcagc ttgcagccga tttattttac
     3121 aaaagggcat cctttcgact acttttcttt gaacatcgat gcttttttga ttgtcgctga
     3181 tacaggaatc aaaggacaaa caagagaagc cgtcaaagat gtcgctcacc tctttgaaac
     3241 ccagcctcat gaaactggac aaatgatcca aaaattagga tacttgacga agcaagcaaa
     3301 acaagcaatc attgaaaatt caccagaaac gttggcacag acaatggatg aatcacaatc
     3361 acttctggaa aagctgacaa tcagcaatga ttttcttaat ctattgatcc aaacagcaaa
     3421 agataccggg gcattgggtg ccaaattaac tggcggtgga cgcggtggct gtatgattgc
     3481 attagcacaa acaaaaacaa aagcccaaga aatcagtcaa gcacttgaag atgcgggtgc
     3541 tgctgaaact tggatacaag gattaggagt acatacctat gtttaaaggc aaagcacgcg
     3601 catataccaa cattgctcta atcaaatatt ggggtaagaa aaatgaagaa ctcatccttc
     3661 caatgaacaa cagcctttcg ttaacattgg atgcatttta tacagagaca gaagtcatct
     3721 tttctgatag ctatatggta gatgaatttt atctagatgg caccttgcaa gacgaaaaag
     3781 caacaaaaaa agtcagtcag tttcttgacc tttttcgtaa agaagccggc ctctcactaa
     3841 aagcttcagt aatcagtcag aatttcgttc ctaccgcagc tggattagcc tcctctgcca
     3901 gcgggctagc tgctttagca ggcgcttgca atactgctct taagcttgga ttagatgatc
     3961 tctctctttc aagatttgct cgacgcgggt ctggttcagc ttgccgaagt attttcggtg
     4021 gtttcgtcga atgggaaaaa ggccatgacg acttaagttc ttacgctaag ccagtccctt
     4081 ccgattcttt cgaagacgat ttagcaatgg ttttcgtttt gatcaacgac cagaaaaaag
     4141 aagtgtccag cagaaatggg atgcgtcgga cagtcgaaac atccagtttt tatcaaggct
     4201 ggttagattc cgttgaaggg gatctatatc aattgaaaca agcaatcaaa acaaaagatt
     4261 tccaacttct cggagaaacg atggaaagaa acggactaaa aatgcatgga acgactttag
     4321 ctgcccagcc tccattcact tactggtctc ctgacagctt aaaagcgatg gatgcggtgc
     4381 gacaattgag aaagcaaggc attccatgct actttacgat ggatgctggc cctaatgtca
     4441 aagttttagt ggaaaacagc catttatctg aggtacaaga aacatttacc aaattattta
     4501 gcaaagaaca agtaattact gcacatgctg gtccaggaat tgcgattatt gaataaaggg
     4561 agatttttat gattgaagta tctgcaccag gcaaactcta tattgccgga gaatatgcag
     4621 ttgttgaaac aggccatcca gcagttatcg ctgcagtcga tcaattcgtg acagtcactg
     4681 tagaatctgc acgaaaagtc ggaagtatcc aatctgcaca atatagtggg atgcctgtac
     4741 gttggacaag acgcaacgga gaattagttt tagatattcg ggaaaatcct tttcattata
     4801 tccttgctgc tattcgcttg actgaaaagt atgcacaaga aaaaaacatt cttttatcct
     4861 tttatgatct gaaagtaaca agtgagttag acagttcaaa tggccggaaa tatggattgg
     4921 gttctagcgg tgccgtgacc gttgcaacgg tcaaagcctt gaatgttttt tacgcgttga
     4981 atttatctca gttggagatt ttcaagattg cagcactagc caatttagca gttcaagata
     5041 atggttcctg cggcgacatc gctgctagct gttatggtgg ctggatcgct ttctcaacct
     5101 tcgaccatcc ttggctccaa gaacaagaaa ctcagcattc tatcagtgag ttacttgccc
     5161 tggattggcc aggtctatcc attgagccat tgattgctcc tgaagattta cgtttattga
     5221 ttggttggac gggtagccct gcctctactt ctgatttggt cgatcaagtt caccgttcga
     5281 gagaagataa aatggtggct tatcagcttt tcttaaaaaa tagtacagaa tgtgtcaacg
     5341 aaatgatcaa agggtttaaa gaaaataatg taacgttgat ccaacagatg attcgaaaaa
     5401 accgacaatt actgcatgat ttatctgcaa tcactggggt cgtcatcgaa acgcctgctt
     5461 tgaacaaatt gtgtaattta gctgaacagt atgaaggagc cgcaaaatct tctggtgcag
     5521 gtgggggcga ttgcggaatc gtaattgttg accagaaatc tggcattctt cctttaatga
     5581 gtgcatggga aaaagcagaa atcactccac tgccgttaca tgtctatagc gatcaaagaa
     5641 aggaaaaccg atgaatcgaa aagacgaaca tgtttcacta gctaaagcct ttcatgataa
     5701 acaaaaaaac gaatttgact tcgtacggat catccataac cctttgccgc aaatagcagt
     5761 ttctgatgtc gatctaagta cacaggcagt tgggtttaca ctaagcagcc cattttatat
     5821 caatgcgatg actggcggaa gcgaaaaaac aaaaaaaatc aaccaagatc ttgcaatcgt
     5881 cgcaagagaa gcagatttga tgattgccac tggttcagtc agcgctgcct tgaaagtccc
     5941 ttctttagcc gatacttata cgattatgcg acaagaatat cctcacggga aaatcattgc
     6001 caacatcggt gcagggactt ctgtcgaaag agccaaagaa gctatccgat tgtttcacgc
     6061 agatgcctta cagattcatt tgaatgcacc tcaagagttg gttatgcctg agggagaccg
     6121 tgattttacc aattggaaag tacttattca agaaactcaa acagccattg acgtccccct
     6181 catcgtaaaa gaagtcggtt ttggcatgac aagagaaacg ctcaatgatc tagctgcttt
     6241 aggagttcat acagttgata tcagcggtcg aagcggaaca agcttcaccc agatcgaaaa
     6301 cgcccgtcgc tccaagcggg aactgagtta tttagctgac tgggggcaat cgacagtctc
     6361 ttcattgctt gaagcaaatg aagcagacac ttctatggaa atcctagcct ccggaggtat
     6421 ccgcaatgcc tatgacatat ttaaagccct ttgtctcggc gcaaatgccg tgggtacttc
     6481 aggaaccgta ctgacgcatc tgatgaatca cggcgtagaa gaaactatta tactgatgaa
     6541 gcaatggcaa gaagagcttc gtctgcttta tactatggtc ggcgcaacga ataccgcggc
     6601 cctacaccaa caatctctga tcttttccgg accagtgaag gattggtgcg aagcaagagg
     6661 gatcgactta gtgaagtatg gaagacgcac agaaaagagc gtgggacaaa agtaaagaac
     6721 acttttgtct cacgctctaa acacgtacaa acggcggaag taaaagcaac tccttcggaa
     6781 ataagctgaa attcacaaaa atttgaaaag caattttcgt gaattccttc ttatttcttg
     6841 gagttaaatg cttctgtccc agcctctttt ttcgaataaa tgatgtttaa tcagctgtcc
     6901 ttcggtattc gttcaatccg ctgatttcac aacctctcca ctaaacagtg tactaaagct
     6961 cttttaaggt tgttttccga tataggcaag tatgcctccg tccacataca agacatggcc
     7021 gttaacgaaa tcagatgcgc tagaagccaa gaagacagat ggtccagcca aatcgattgg
     7081 ctcgccccag cgtgctgctg gcgtacgtcc aacgataaat tgatcgaatg gatgacgttc
     7141 accgttttct tgtgtttcgc gtaatggagc agtttgcggt gtagcaatat aacctggtcc
     7201 aattccatta cattggatat tgtattgacc gtattcagaa gcgatgtttt tcgtcagcat
     7261 ttttaatccg ccttttgccg cagcataagc actgaccgtt tcgcgtccta attcactcat
     7321 catggagcag atattgatga ttttaccgcc gcctttttcg atcatatccg gaataactgc
     7381 ttttgaaacg atgaatgggg catttaaatc cacgtcgatt acttggcgga agtctgccgc
     7441 atccatttcg atcatcggtg tccgtttgat gatccctgca ttgttgacta gaatatcaac
     7501 tgaacctaca tcttctttga tctgttgaac catcgcttga accgcttctt catcggtcac
     7561 atcgcagaca taaccttttg catcgatgcc tgcttcttta taatgcgcta taccttcatc
     7621 aactgattct tgattcaagt tattaaatac gatttttgct cctgctgtag ctaaagagcg
     7681 tgcaatctca aatccaatac catagacagc accggtgact aatgctactt ttccatctaa
     7741 acgaaacata tccatactaa attccatcat tttctctccc ttatgcttat tttaattgat
     7801 ccatttgcac catatccatg tctgtatagg tgatattttc tccgcacatt gcccagatga
     7861 atgagtaatt gcttgtacct acacctgaat ggatcgacca gcttggcgaa ataatggctt
     7921 gttcattgtc tacaactaaa tgttttgttt catctggttt gcccatcatg tggaacacac
     7981 gtgtatcttc attggcataa tcaaagtaga cataagcttc catacgacgt tcatgtgtat
     8041 gacaaggcat cgtattccaa gcgcttcctg gttctaaaat cgtataaccc atttgtaatt
     8101 gacagctttc gcatacattt ggatggatgt attggtagat tttacgttca ttcagtgtca
     8161 ggccttcacc agtctccatt ggttttactt ggtcgatact gatttttaca tttggatatt
     8221 tatgatgagc tggaacagaa ctaatataga atttagctgg gttttcagca tcttgagaag
     8281 aaaatacaac atgtcgtgtt tcttttccga tatagtatcc gtcttgtttt ttcatttctt
     8341 ctttttgccc atcgatctcg atgaatcctg gtccaccgat attgatcaca cctagttcac
     8401 gacgctctaa gaagtaatca acacctagtt ctttgtctaa tgtgatttct aattcttttt
     8461 cagtaggtgt cactccacca aagatcattc gatcgttgtg cgtataagtc aaactgattt
     8521 tccctggttc aaataccttt tctactaaaa attcttttct caattgttcc gttgaataat
     8581 gacggatatc ttctggactg tgtgtataac gtgtttccat ttcttgcatt ttcttctact
     8641 ccttctatcg aatgattttt ccagagccgc atgctaaaaa ttgtgcgact tcttcttgac
     8701 taaattggtt gcagtcccca tggatcgtat gcttcaaggc agaagctgcc gtagcaaaat
     8761 caatgatttc ttgcggagac atattggata aaatcccatg gagcacgcca cctgcaaaag
     8821 catctccgcc acctactcga tccacgattg gggtgattct atggacttgg gattccacat
     8881 attcatggtt catccacaat gtccccttca attcattttc acttgctgaa tgaacggtac
     8941 gcttggtcga ataaaacacc tgaatattcg ggaacttttc ctgcattttt tgataataat
     9001 aaattagagg ttgttcttct gcttctggcg ctttctcgat acctaacaaa taaagagcat
     9061 ccatttttcc agctgagcag atatctacta aaggtaaaag ctgatggatt acttcgctgg
     9121 cttcttgctg tgtccataat tttccacgat agttgatatc gaagctgatc aggcagccag
     9181 ctttttttgc agcttctatc acctgtttcg tcattttttg ccatttttta gacaaagctg
     9241 gggtgattcc tgaaacatga aatatatcta ttccttggaa taactcctct agcgaccatt
     9301 ccaaatgatc catttcagca aaacttgatc cggcacgatc atagatcact gaggcggcgc
     9361 gttcgccact accagtttcc atataataag tacctagtct tgatccacca gataatacct
     9421 gtttcgtatc tactccataa cattgcaagt gctttttgac tgcttttccc aatgcgttat
     9481 caggtacttt tgtagcaaaa atcgcttcat gtccgtaatt agctaaagaa attgctacgt
     9541 ttgcttcccc tccgccataa tgggcagcga atcgttcact tgaatcgata cgggttccct
     9601 gctctgtgga caatcgcaac atgatttctc cgagtgtcac tacttttccc ataagcagct
     9661 acctcttgat ttctttcatt tttgctgcat actgttgcgc gacttccgtt actttgtcaa
     9721 aatctcctgt agctgcgggt gctaaaaggt tcccacctac tccgactgtt acgacaccag
     9781 catcgaacca ctctttcata ttgtccagac tcacaccgcc agttggcatg atattgactt
     9841 gaggcatcgg cgccttgaag gcagaaatga tacttggtcc ataagcgctt ccaggaaata
     9901 gtttgacgat atctaccccg cttttcagcg ctgttttgat ctcggtaata gtcatacatc
     9961 ctggtaagta aggaatttga tacagattgc acatctctgc cgtttcttga tcaaaggaag
    10021 ggctaacaat atactctgcg ccagctaaga tagccaagcg agctgtgaca gcgtctaata
    10081 ctgtgcctgc gccaatcact atttctggtt ggtctttgta gaatgacaaa agttctttga
    10141 ttacttgatc tgcttgaggg actgtaaaag tcaactcaat accagttaga ccacctttga
    10201 tgattgcgtg gcaagcattc aaagcttctt ctttgctttt tccgcgtacc accgcaatca
    10261 ctccggcgtt tttcaatcga gataaaatat caattttttt catcttctcc acctatttcc
    10321 tatttagaaa ttttatttta taacttggaa atctataccc atattatacg gcagaaaaga
    10381 aaaattgcaa acgctttttt cattattttt gaattctttg ctcgatttcg ctttttgttt
    10441 gcttgagggc actgattatt tgttcttttg tctcatctgt taaacgatat ttcggcatac
    10501 ttacactaaa tgcaccaatg atttgttcgt ttttcacgat tgaggctcct atacaaaaaa
    10561 tatcacgttc gatttcttca tcgtcaaatg cgatgtgggt ttcttttacc gtttggattt
    10621 cctttttcaa ccgtaatgca ttggtgatcg tatattctgt gtaagggatc aacggatgct
    10681 tttcaagata atcagtgtac tgctcttcac tgaattctgc taatacggct ttgcccatcg
    10741 cagaattgta taatggtcgg gtgattccga tttttgaaga catgcggatc gtttgatgtt
    10801 ttggatctag tttgttcacg tacaagatct cattgttgtc caatacccct aagtggatag
    10861 tctcatcgat cttttgctgc agctgttcta aaaacggtaa agtcaactct accaaatcga
    10921 tttgttcaat gtttttattc gcgtagcgaa taagctttgc acctaaacga tagtttttct
    10981 ctgaattttt atttacgtag ccgatcatca acaaagtatc tagtattttc aagactgtag
    11041 aagaggtcat tcccacaccc tttgcgatcg tctgcaaaga gacatcttgg ttttccgcta
    11101 aatagtctag tattttagag gctttgatca atacagttcc ataaggcttt ttattttcca
    11161 tataatattc tcctatttct ttataagaaa aattatagcg gaaataccat caatttaaaa
    11221 gagatatcca gatataaact accatttctc tttacaggca atttaatgtt gaagatccgc
    11281 ttcgttttta catcaaactt tgatataaag caatgatttc ttctactgtc gtttctcttg
    11341 gatttcctgg tgtgcataca tctcgcaaag catcttctgc aattgctgga atatctgctt
    11401 cttttacacc taattcagaa atggtttctg ggattccaac cgctttgctc aaccgatcga
    11461 tctcaccaca agccgcttct cttacatctt ctaaagacat ttcagctgct cctttaatcc
    11521 ctagaacaag agcgatctca cggtactttt ctccagtata ttctttgtta tatttcatga
    11581 cagttggcaa aagtgctgca cacgctacgc catgaggaat gttgtaccat gcacttaacg
    11641 ggtgagccat cccgtgtacc agtcctaaac cgacatttga gaagcccatt cccgcaatat
    11701 actgtcctaa tgccattttt tctcgcccat tttgatcgcc atctacagaa gcttccaaag
    11761 aatggccgat gatttcgatt gcttttaaat gcagcatatc agtcatttcc caagcgcctt
    11821 ttgtgataaa cccttcaata gcatgcgtca tagcatccat acctgttgat gcagccaatt
    11881 ttttcggcat tcccatcatc atatcgctgt cgatgaacgc gacgattggg atatcatgag
    11941 gatcaacaca aacaaatttt cggtgattta cttcatctgt gatgacgtag ttgatcgtta
    12001 cttctgctgc tgttccagaa gtcgttggta tagctaatat aggtaaacat ggatttttcg
    12061 tatcagcaac accttctaaa ctaatgacgt ctgaaaactc tggattcgtc aaaataatcc
    12121 caatggcttt tgccgtatcg attggcgaac ctccaccgat tgcgatcaaa cagtctgcct
    12181 ctgcctcttt aacaaaagcc actccatctt ttacattttg gatcgttgga ttaggtacga
    12241 tcccgtcgta taaagcataa gcgattgctg ctttatctag aagttctgtt acttttgttg
    12301 ctataccgtg ctcgatcaat cctttgtcag taatgacagc tgctttgccg aatcctcgct
    12361 gctgaaattc agggacgatc gactcaatcg ctccttttcc aaaatacgat gtttcattta
    12421 aaatcattcg attactcatt ttctattcct cctaatttgt attatttttc acaataaaaa
    12481 cgaaagaacc ccaagcaacc ggttgcccag ttgcttgttg ctacagttca aagactggca
    12541 tcaattccca actgactgga gaggcatctg gatttgtctc catgatatct tccatgtact
    12601 tccaccattt ttgattgata gatgtatttg ccattttttc ccataacttt tcatcttcga
    12661 tcactaagta accaaataac aaacttgtac tcggatcaag atagatcgaa tagtcgatga
    12721 ccccgtgttc acgaagtgct gtacgcattt ctggccaaag ttcatcatgt ctttttttgt
    12781 attcttcttg tttttctggg taaactttca tgcaaaaagc ttttttcacc atgtcagaca
    12841 cctgctttcg tatgaacttc ctccaaataa cctgcttttg gagtgacacc aaacgcatct
    12901 gctaaatgcc acaggttttc gtccgtgatt gtttgcaaga ttggtccttg cgctttgacg
    12961 tacgtataga cttctgctgc cttttctgct gtctcgatca aaccaaagac ttcatccatg
    13021 tcttttcctg acccgtagat tccatgttgt ggccataaaa ccaatcgagt ttctttcatt
    13081 ttttcagctg ttgcttcccc aatctcattt gttcccggaa ccatccacgg aatgatggaa
    13141 attccttctg gaaaaacaac taagcattcc gtacacattt gccatagcgt acgactaaag
    13201 gaacgttcgt ctaattcatg cgtaaaactc atcgctaata gatgactagc atggcaatgc
    13261 ataacgatcc gattatctgg gtctacttct aaacgggcga tatgactcat gaaatgactt
    13321 ggcaactcgc ttgtaggaag gcattcgttt tccagccccc acaaaagttc cagtgttttg
    13381 ccatcttcag caactcgaac gattccaaga ttctcggcag gttcgctcgc tacattttta
    13441 aaatatcttc ctgaaccagt tacaataaaa tagcatcctg ctaaacggct ggcatcaaaa
    13501 atcatcgaga tgcggcggat cactttttca ggatccaaga acggtgtgat ctcttcttct
    13561 tttagtaaat aagaaatatt cccgccattt ctttcatccc atcccaagcg ataaagattc
    13621 gacgtcgttt cgatcatttc tttcacataa ggcgcttgta aaatatctat ttttttcaat
    13681 atagccacac tcctattttc ttaattccaa cacgtctttt tgatattcct ggacttcttc
    13741 cagccaatcc aaaccaactg gaacttgatt tttgtaacag aaataattcc atacatcggc
    13801 atacgggaaa tctttcaatt cttccgtata agccattctt gaagtaaagt caaaagccag
    13861 ctccatttct ttcaatcgct caactggttc cagcatagct ttcagcagtg ctttttgtgt
    13921 atttctcgta ccgatgaccc aagcagcgat acggttgatc gttgcatcaa agaaatccag
    13981 accgatattt gttttttcca acaattcgtt acggactaat tctttagcga tttcctgcaa
    14041 ttcatcatcc atcaaaacca catggtctga atcccaacgc actggacggg aaacatgcaa
    14101 catgattcct ttgctgaata aagctaatga agataattta ttggaaatca cttctgttgg
    14161 atgaaaatgt ccagcatcta gacaaacaag tttgtcacga gtcaacccgt aacccatata
    14221 aaattcatgg gaaccgactg tataagcttc agcgcctaaa ccaaatagtt tgctttctac
    14281 tgcatcttgt acataccgtt catctaactc ttctgtaaaa atttcatcga gtgattccat
    14341 taaacgttcc cgtggggtaa aacgatcaat cggattatct ttcatcccat caggtaccca
    14401 aaagttattg atacttgttt gcccagtttc tttcccaaag tactccgcga ttttgcggct
    14461 tcttttcccg tgttcgatcc agtattcacg aacttcttta tctggatgag ccaatgtaaa
    14521 gccgtctttc atcattggat gcgaaaagaa agtcggattg aagtcaagac cgatttcttc
    14581 tttttttgcc cactctaccc atttttcaaa atgtttcggc tcaatttcat ttagatcgac
    14641 agattcttct gtatccaaat agatagcatg aaggttcaat ttgtgtttgc ccggtatcaa
    14701 cgaataagcc ttctccagat cttgtctaag ctcttcaggt gttcgtgcgg ctcctggaaa
    14761 attccctgtc gccatgattc caccggtcaa ttcgccatcc ggtgtcaaga aacctttgac
    14821 atcatctcct tgccagcaat gcatagaaat tttgatgtcc tgtatctttt ctagtacagc
    14881 atctgtatct acaccgatag ttgcatattt ttcttttgct tgttcgtaat ttctttcaat
    14941 cgtgttcata cgattactcc tttgatttta ttcacgtacc attccatcgt gttttgctta
    15001 ttttcatctg ggtaaaaagt ttcacatgga aacgactgtt tgattacatt tcttgcttgt
    15061 tctatattcg aaaactgacc tgtactgagc atttgcatgg caacattccc gattgctgtg
    15121 gcttcactag gtcctgcttc tacaatgatt ccggcataat ctgctgtcaa ttgattcagt
    15181 agacgattat tcgatccgcc ccctacgatg tgcagctttt ccaatttcgt tccagttaag
    15241 tgttctactt tgatcagctc ttgtgcgtaa caaagagcaa gattatcata cacacaacga
    15301 gcgatagctc ccgatgagac agggactggc tgctctgttt caaaacagta ttgctgaatc
    15361 tcttctatca tatttggggg attcaaaaat cgagggtcat tgatttccat cacttgctgc
    15421 agcggttttt cttttgcagc aagctctgcc aattccgcat aactgtactc gtactcttgc
    15481 attcgggcaa cttcctggat caaccacatc cccatgatgt ttttcaaaaa acgcaccgtg
    15541 ttatgggcac cccattcatt cgtataattt tcagaaaaag cattgcgaga aacattggcg
    15601 atctttgttt caatccctaa aagcgaccat gtcccactgc tgatataacc ccaacgttct
    15661 ccttgacctg gcgttcctaa tacagctgac gccgtatcat gacttgctac tgtgataaag
    15721 gtcacatctg gcaaatcata ttttgaaaat tgttcttttt gcagatctcc tagtatcgtt
    15781 cccggctctg tcaatggtgg aaataattcc ttcgagacac cgattttttc aagaagttct
    15841 atttcccatt cttttgtccc tgcattcagc agctgcatag tagatgcatt agttttctcc
    15901 gtcaccatgt taccagtaaa gacataccct aaataatcag gtatcagtaa caatttatgt
    15961 gcttttgcca aattttcttt ttcttcagca aacaattgga acaaggtatt gaaaggctgg
    16021 atctgaatcc ctgtctgctc atacaactta tctagagaat agatttcaga aaactgttct
    16081 actgctccat tggtacgctt gtcccgataa gcaatcggat catttatccg atccccttgt
    16141 tcatcaatca gacagtaatc gactgcccat gtatcgatcc ccgcaaaaag gcgatcaatc
    16201 cctgtctgct ttaatttttc aaatccaatc aaaatctctt tgataagata atcgatcttc
    16261 cagcgatcgt gaccgtcttt gttccgaaag ccgtttttga accggtgtac ttcttccaag
    16321 atcaaagaac cttttgcatc cctcgtactt ttcattagtc gtccgcttga tgcaccgata
    16381 tcgatggcaa caaatgttgg attcatttct ccacctcttt tactttattg ttgattagca
    16441 ctttattaat aaagcgttat catttattaa caatgctatc ataatacaga atcttatatt
    16501 ttgcttcaca ctattttggt atataattgc attatcttga caagttggga gtgtttacat
    16561 ggattactgg gaaaaagcca accactcatg gtcggaagac tcaaaaagag tgatcttgac
    16621 gcctacacaa agaagcagga atttattttt ttatatccaa gaaatcggtt acttcaaagc
    16681 accaatccct tactatactg aacgagcaca tttaccttct tacttgataa agtttacttt
    16741 gtctggcaaa ggttcgctta catataatga taatcagcaa cagctaaaag ctggagactt
    16801 attttttatt gactgccaag aatatcagcg ttatcaaacg atcagcgaag aaccatggga
    16861 aatggattgg atccatttga atggtcagaa cgtccaatca ttttatcagg agttcacaaa
    16921 agacggccat aacaccttcc attcaacagg ggatccatca gaaaacaaga tccaccattt
    16981 gatcacagaa ttgatccaca tgcaacaagg cacgaatgcc cgtaccgatt tccagtcctc
    17041 tgtagctatc cacgagttgc tgaatgaact gattttgcaa aagtatcagc tagatttcga
    17101 agaagaggat attcccgcct acgtttacaa actgaagcaa tacttagacg aacatttcaa
    17161 agaaacgatt acacttgatc aattagaaca acaattctta ttgaataaat atcagctgag
    17221 caaagatttt tccaaattta tcggttctcc accaatcgat tatttgatca gcaaaaaact
    17281 ttcttacgct aaagaccttc ttcggtatac agaatttacg gttcgaatga tttccgaaga
    17341 aatagggatt gagaattttg cttactttag ccgcctgttc aaagcaaaaa caggactatc
    17401 gccgagagac tttcgtaaat tcagctgatt catataatat gtacgtcatt ttttcaaaat
    17461 attttgaaat atatagataa aaataaaata accgcagttt ctgcttctat gtaaacaaca
    17521 gcagctactg cggttatttt ttagtgatca ttctcattgt tcatcttcaa aatgttcata
    17581 atgaaccaac tgtttctgtg tatcacgttt caaaaattct ttaggcgtta tgccgaactc
    17641 tctcttgaat gctttcagaa aatgcggata agaagaaaaa ccacttttac tatatacagc
    17701 actagagctg cggtattctc gcaacaagtg cttggcatag atcagctttt tcttcattac
    17761 atactgatga aacgtaaatc cagtgtactt tttaaattct cgtgtgatat ggtatttgct
    17821 gacaaaaaac tgcttttcca tttcctctaa agaaagcgga tgagataaat tttttgagat
    17881 atattgtaac atttgttcca cacgctcatt aggaactaca gcattctgtt cttgcgcact
    17941 ctcttctttt tgtacaactt gattgagaaa aatcaagtat tctaccagag cttgttcata
    18001 ttttatgtct tcaccgtaaa tttttttatc aggaggatgg tcgataaatg ataatttttg
    18061 cttcaatact tcctgttcta tttgcaatac acgactcctc ttctctccca ttggttgaaa
    18121 gcaagccgat agattagacc atggcgtgga acgactttct agaaaagaag gggtgacaaa
    18181 gatatagaca cgctcgaata catctgaaga ttggcggacg atacgatgca aatcattgga
    18241 atggatgagc agcacacttc ctgctttgat cgtaaattgt cgtccgttca aataaaaagt
    18301 cgcttctccc tttaatgtag catggatctc atagaaatca tgatgatgat agatcgtttt
    18361 attttggctg acgacatctt tgacatgata gatttcatac tgatcagaaa ccatcgtatt
    18421 gacttgttca ccgctgattt tcttttggag catgtgccgc acctcctttt gttcacttat
    18481 gcacaatttt attataccac gttttttgta atcaaaaaga gctgctttta tatactctta
    18541 taaaaaagaa gagacgtggc atcttctagc cccgccccct ccattctaaa tattagttaa
    18601 ccaacgtctt ctttacatta ttcaagaaga cttcttccat aacgaatccc atcatctttt
    18661 gtttcttcaa gaaccacata caggtacgga cgattcttca tgatgatttc tttgattttt
    18721 gtgtactcga tcacaccgtc tcccaaattt accggcacga ttttttcctg ttcgacacga
    18781 aaatctttca aatgaaccgc acatatcttt tcaccaaaac gttcaaaagc ttcttctacc
    18841 aattggactt gttcttgata atcactactt gtgatcaaat tggtcggatc taaaatgatt
    18901 cctagatagt ccgaatctac tgcttggatc agctgctcta cccttgctaa agaatacacc
    18961 ggatgattca aacctggttc tatccccacc atcatttggt atttttctcc agcttttacc
    19021 aagcgacgga taacggacac agcttcagca aatgcttcat ctgtgaaatt ttcttccgta
    19081 tattggattt ccggcaaaac acatccagtt tccgaagcaa ccatcgacgc accaaaggaa
    19141 gaagcatagc gaagatactg ctcgaacttt gtcagcaact cttgtcgtat cgttaaatct
    19201 ggatgaatca tattgatata gcaacttaaa attcctacgg tcacttcttg cttttctaaa
    19261 actcgtttga cataatttcc catcccagaa ttgatctcat ttgcgccaga aggtatttca
    19321 ggaaacgaaa gacctaaggc gagctgcagt gtatgaatcc cttgttcttt tgttttttct
    19381 gcaagatctt ctatcgtttg gacttcggaa agatcatgtc ctctaattgt aatgttcaac
    19441 ataactattc tcctaactca gcatattggg tagccacatg acgatttgcg ggaagtaagt
    19501 aatcaaaaac aagacgacta agataacccc ataaaaagga agaagcggtt tcagcattgc
    19561 ctctgctttt acgcctccta cacttgcacc gacatatagt cctgtaccta ctggcggcgt
    19621 gatggagcct acacacagat tcatgattga aaacaacccg taatgtacag gatcaacccc
    19681 tacacttgtg acgattggta aaaatattgg tgtaaaaatc aagatagcag gcgccacatc
    19741 cataaacata cccaccagta ataacacaag attgactaat aacagaataa taaatttatt
    19801 atccgttacg cccataatca acgaactaat tgcctgagga ataccggtaa acgccatggc
    19861 gaaagacatc atggaagaag tagccaataa gaacatgatc gtccctgaca ttgctactga
    19921 ttgaaacaac atattaggta tatcttttag ttttaccgtt ttatagtaaa acatagcaat
    19981 caacagggag taaatgacag ctatcgctga agcttctact gctgtaaata tccccgtcaa
    20041 gataccaccg ataatgatga caatcaatag aaggctagga atcgcctctt ttattatttt
    20101 tccagcatga gccatctgtc ctttttcgac aacagggtat ttattctttt tagcaacgat
    20161 gaatgctact agcatgattc ctagcgccca caaagcgcct acgagataac ctcccataaa
    20221 caaagcagag atcgaagcac caccagcaac aagtgaatac atgataaaag cagtacttgg
    20281 aggaatgacc atacctgtcg gagctgacgc gatattgacc gctgtcgcaa acttccggtc
    20341 atatccttct tccacttgct gagggatcaa cactccgcca atcgcggtag aagcggcaat
    20401 ggccgagcta gagatggaac caaataaagc attccctaac acattcgtat gagccaaagc
    20461 ccccggcacg cgcccgacga acaacatcgc aaaatccact agtttcttag ctatccctcc
    20521 attattcatg ataatgcccg agagaacgaa aaacggaata gcgatcagcg aaaaactatt
    20581 gatacttccc accatttttt gagctgaact aaaagcagaa acatcaaacg gtataactaa
    20641 caataaagtc atcatcgatg agaatgcaat acttatagca atcggcatcc ctaatacaag
    20701 caacacaaca aatacaaaaa ataacactaa tccggcttct attgccattt tattcctcca
    20761 tttttatatt ttttcttgaa ttgctggctt gttgcttaat gtatcgatta gattgatcag
    20821 gctatagata atgatgagta cccccgatac aggtactgac agataaacat atcccatagg
    20881 aatacttaaa gaaggcgaga tctgccccat tgtcaatgtg acagcattcc atccgccata
    20941 caccatgatc atcgcagcaa ataccagaaa taaactttga acaacaactt ctaaaatttt
    21001 actttttttg ccagttaatt tttcacttaa aaccgttacg gctaaatgtg ctttttgtcc
    21061 cacaacatac gcggaagaca acatggcaaa ccagacaaga ccgaatcgaa caagctcttc
    21121 cgtgaccgta tttggatttc ctaaaaccgt tctggaaaat acttgccata aaacaacagc
    21181 gaccatccca acaagcaaaa cagctcccag gatctctaat accttgttta aaatcatttt
    21241 catcacagct acgctccttg ctcttggatc ttttgataaa ggtctttgta ggtaggatcg
    21301 tttttgaata tatcatgaag tggggcaact gcctctcgaa acggtgtatt atctacatca
    21361 ttgaattgga ctccatgttc ttcttgtgct aaagcttttt cttcttcaat tgcttttgca
    21421 aaagcttcaa tttcaaaaac cgttgattct ttcgctgctt cttcaatggc tttttcctgc
    21481 tcatcagtta gctgttcttt gatggcatca ttcatgatga tgatatctgg cacacgtgta
    21541 tgctcatcat aggaatagta tttagccaca ccaccatgtc cagctgtata caagacaaat
    21601 tcattgtttt ctgatccgtt gatcaaattg gattgaagag acgtgtacac ttcatcactt
    21661 cccataggta cgggcgaacc gcctaaaagc tctaccattt tgatagcggt ttcgctttgc
    21721 atcacacgga tcttctttcc cttcaaatct tccggcgtat ggatcggacc gtctaccata
    21781 taaaagctgc gctgaccaga atcataatag gtcaatccgg taaatcctaa atttttggtc
    21841 gattggtaga ttggctccat tatttcttca ttatccatca ccttaaagaa atgttcttca
    21901 tcattgaata gataaggaac tgaaaaaatc gaataatctt tagagaaact ttccaacgct
    21961 gaggcactta cttttgtgaa atctactgct cctgactgtg tcaattcgat cagttcacgt
    22021 tctccaccca gttgtccatc tgggaaatac tggatctgta cggaaccatc tgttttttct
    22081 tttactaaac gcccaaattc attcattgca tcaattactg gctggctgtt gcttgcataa
    22141 gcaaagcgca aggtaactat ctcatttaca tctgcatctg cgacagttgc cacactagaa
    22201 ttatttccgc agccgcttag acctagcaga cctaggctaa gcgaacttgc tgcaaacagc
    22261 agtgatgttt ttttcatatg ggtttccttt cttttaacaa taagagacga gcaattctgt
    22321 caaacaaagc accgttaacg actgtccata aggcattgct gtgattccga tattccgata
    22381 aaaatctaaa ctgtccccca ttcctgtccc gattgaaacg ttttgaactt ctcctttttc
    22441 atcgatttgt tcaagcaatc cttggatagc acgataagcg acttctttat attcttgtgg
    22501 taaataacgt ttatggaccg ctttcaaaat accgtaagca aatcctgcag ttgcagaaga
    22561 ttctacgtaa gaagaaggat catccaacaa cgtatgccat aaaccgcttt cagactgata
    22621 agtttttaat gcacgcactt gtgcttcaag tgtttcgatc aataatttgc gcaatgcatc
    22681 ttctttcgat aattctaaga tttcaatgat ctctggaata gcaatcgtca accagcagtt
    22741 tccacgagcc caaaatgctt cggcatagtt atgatttcct tcaaacgtcc agccgtgata
    22801 ccacaatcct gttcgtttat ccatcaagta tttgatatgg atcataaact ggtaacgagc
    22861 ttcttctaaa tattctgggc gattcaacag tttcccgatt tttgccaaag gaagcactgt
    22921 catcatcaat gtatcgtccc acaactgatt cttattttcc ggtccatatg tggcatgctg
    22981 taacccgtct tcatttgtcc gaggcatgtc attcatgacc cattctgccc attgttctaa
    23041 ataaggcaaa tagcgtgaat ctttcgtgtc ttcatacaag taagccatag tcaatagcgg
    23101 tgccattgta ttgacgtttt tgggcggagc gccttcttcc atacgatcct caaaccattc
    23161 attgaccact tgataagcgc gaggattttt tgtcatctgg taatttttat aaataccata
    23221 tagaccgaca ccttgtggcc aattccacac tgtccagctt ttgtcatcta ctttcagtcc
    23281 atcaaagtcc aacaaaaatt caccattatc gtctttgatc gttgtcaggt tttcaacgag
    23341 caggtcaatt ttttctttca ctaattcttt aggtacaaaa atctcttctt taataatcat
    23401 ctttacgcca cttttttaaa cgctttcatt ttatatcctt aatatagcag taataccgtc
    23461 cactataaat atcgcttttt gaacaaaaac tgtctaaaat tgacctaaat gttaaataac
    23521 aaaagtaact ttcagttact tggaaattaa aaaaagaact tggagaaaca acgttt
//
LOCUS       DARPZJ010000039        23571 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.040, whole genome shotgun sequence.
ACCESSION   DARPZJ010000039 DARPZJ010000000
VERSION     DARPZJ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.040"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="SLE23_001860"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="SLE23_001860"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEI8468761.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="SLE23_001861"
     CDS             complement(1172..1867)
                     /locus_tag="SLE23_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEI8468762.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="SLE23_001862"
     CDS             complement(1880..2596)
                     /locus_tag="SLE23_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEI8468763.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="SLE23_001863"
     CDS             2926..3531
                     /locus_tag="SLE23_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HEI8468764.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="SLE23_001864"
     CDS             3856..4179
                     /locus_tag="SLE23_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEI8468765.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="SLE23_001865"
     CDS             4361..5731
                     /locus_tag="SLE23_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEI8468766.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="SLE23_001866"
     CDS             complement(5861..7162)
                     /locus_tag="SLE23_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEI8468767.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9350)
                     /locus_tag="SLE23_001867"
     CDS             complement(7392..9350)
                     /locus_tag="SLE23_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEI8468768.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="SLE23_001868"
     CDS             complement(9527..9793)
                     /locus_tag="SLE23_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8468769.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="SLE23_001869"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="SLE23_001869"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEI8468770.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="SLE23_001870"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="SLE23_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEI8468771.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="SLE23_001871"
     CDS             13137..13700
                     /locus_tag="SLE23_001871"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEI8468772.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="SLE23_001872"
     CDS             complement(13953..14474)
                     /locus_tag="SLE23_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEI8468773.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="SLE23_001873"
     CDS             complement(14477..15319)
                     /locus_tag="SLE23_001873"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEI8468774.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="SLE23_001874"
     CDS             complement(15312..16037)
                     /locus_tag="SLE23_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HEI8468775.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="SLE23_001875"
     CDS             16213..16509
                     /locus_tag="SLE23_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468776.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="SLE23_001876"
     CDS             17077..18669
                     /locus_tag="SLE23_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8468777.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="SLE23_001877"
     CDS             18682..19422
                     /locus_tag="SLE23_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEI8468778.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="SLE23_001878"
     CDS             19590..20939
                     /locus_tag="SLE23_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8468779.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="SLE23_001879"
     CDS             complement(21067..21657)
                     /locus_tag="SLE23_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEI8468780.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="SLE23_001880"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="SLE23_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEI8468781.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6750 a         4746 c         4490 g         7585 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact gacttttgaa caccgtttat
    23281 tgagaggtcg tgaaaaagcc gcttagtttc aagtattaag aaatattttg tgaaaatggc
    23341 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctggcttttg aacaccgttt
    23401 attgagcgtc tataaactga cctgagtatt agagaaacaa aacggcaaag tagctccata
    23461 tactttgccg ttttgttttg aactaatacc gaagagaagc tgatcaaaca acatttcttt
    23521 tataatatag attttagaca tatatatgat ataaaaatag ttttcgcaaa a
//
LOCUS       DARPZJ010000040        22132 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.041, whole genome shotgun sequence.
ACCESSION   DARPZJ010000040 DARPZJ010000000
VERSION     DARPZJ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.041"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..523
                     /locus_tag="SLE23_001881"
     CDS             <1..523
                     /locus_tag="SLE23_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEI8468782.1"
                     /translation="GGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGIVA
                     NCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIFGS
                     LIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILTVL
                     LLPLFFQPFAGLF"
     gene            523..2109
                     /locus_tag="SLE23_001882"
     CDS             523..2109
                     /locus_tag="SLE23_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468783.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2128..2349
                     /locus_tag="SLE23_001883"
     CDS             2128..2349
                     /locus_tag="SLE23_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEI8468784.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2346..3107
                     /locus_tag="SLE23_001884"
     CDS             2346..3107
                     /locus_tag="SLE23_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEI8468785.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            3487..3996
                     /locus_tag="SLE23_001885"
     CDS             3487..3996
                     /locus_tag="SLE23_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEI8468786.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4071..4610)
                     /locus_tag="SLE23_001886"
     CDS             complement(4071..4610)
                     /locus_tag="SLE23_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEI8468787.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="SLE23_001887"
     CDS             complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="SLE23_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEI8468788.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            5623..6474
                     /locus_tag="SLE23_001888"
     CDS             5623..6474
                     /locus_tag="SLE23_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEI8468789.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            6502..7137
                     /locus_tag="SLE23_001889"
     CDS             6502..7137
                     /locus_tag="SLE23_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEI8468790.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7157..7930
                     /locus_tag="SLE23_001890"
     CDS             7157..7930
                     /locus_tag="SLE23_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8468791.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8338..9135
                     /locus_tag="SLE23_001891"
     CDS             8338..9135
                     /locus_tag="SLE23_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HEI8468792.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9113..9526
                     /locus_tag="SLE23_001892"
     CDS             9113..9526
                     /locus_tag="SLE23_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEI8468793.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            9510..12155
                     /gene="mutS"
                     /locus_tag="SLE23_001893"
     CDS             9510..12155
                     /gene="mutS"
                     /locus_tag="SLE23_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEI8468794.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12173..14281
                     /gene="mutL"
                     /locus_tag="SLE23_001894"
     CDS             12173..14281
                     /gene="mutL"
                     /locus_tag="SLE23_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEI8468795.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14303..14863
                     /gene="maf"
                     /locus_tag="SLE23_001895"
     CDS             14303..14863
                     /gene="maf"
                     /locus_tag="SLE23_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HEI8468796.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(14948..16936)
                     /gene="treP"
                     /locus_tag="SLE23_001896"
     CDS             complement(14948..16936)
                     /gene="treP"
                     /locus_tag="SLE23_001896"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEI8468797.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17159..17872
                     /gene="treR"
                     /locus_tag="SLE23_001897"
     CDS             17159..17872
                     /gene="treR"
                     /locus_tag="SLE23_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEI8468798.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            17949..18395
                     /gene="msrB"
                     /locus_tag="SLE23_001898"
     CDS             17949..18395
                     /gene="msrB"
                     /locus_tag="SLE23_001898"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEI8468799.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            18565..19167
                     /gene="ruvA"
                     /locus_tag="SLE23_001899"
     CDS             18565..19167
                     /gene="ruvA"
                     /locus_tag="SLE23_001899"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEI8468800.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19180..20181
                     /gene="ruvB"
                     /locus_tag="SLE23_001900"
     CDS             19180..20181
                     /gene="ruvB"
                     /locus_tag="SLE23_001900"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEI8468801.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20210..20788
                     /locus_tag="SLE23_001901"
     CDS             20210..20788
                     /locus_tag="SLE23_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8468802.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            20840..21322
                     /locus_tag="SLE23_001902"
     CDS             20840..21322
                     /locus_tag="SLE23_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEI8468803.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            21439..21813
                     /locus_tag="SLE23_001903"
     CDS             21439..21813
                     /locus_tag="SLE23_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468804.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7237 a         3991 c         4790 g         6114 t
ORIGIN      
        1 cgggggcaat tttttgacta tgctgattac tcctgcgaca gtggcacttg ccatccctct
       61 ttataaaaac ttccgtttac tgaaagagaa tttttatcct gtaatggctg cgattttagc
      121 aggaatagtc gcaaattgct tggttagtgt agggttcggt tacttcttct ctcttcataa
      181 agagatggtg atctcattac tacctaaatc tgtaacgacg gctatttctg tcgatttatc
      241 tcatacgatg ggcggggtga atgccgtgac acttgctatt gttgtctcta caggtatttt
      301 tggttcgctg atcgccactc atattttccg cctattcaag atcgaaagtc cagttgctcg
      361 cggtgtggcg ttaggaagta cttctcatgc tattggtaca gcaaaagcaa tcgagattgg
      421 tgaaatagaa ggaatcattt ccggacttgc gatatgcgtc aacggaatat tgaccgtttt
      481 attgctaccg ttattctttc agccttttgc tggcttgttt tgatgcgaaa accactattt
      541 tatgctacaa taaccaaaac gttcgagcat aaaaaaggag ggaaagacgt gtatttgtct
      601 tccgagtatc ttaaacaatt tgataaagat ctatattata agattctcct cctagaaagt
      661 tttgaggatc aagcttggca taccgctgca caattagcgc aagttgttca gctggatgcc
      721 cgcagcgtgt cgaaatacct gaacgagctg tctaaaaact atcagcagtt tagcggtaag
      781 acacaccctt tgtttacaaa aaatcaccgt tctggttata acttttatga tacgctcgat
      841 tcaattgaac atgagcgttt tttgatctat ctcgtgcaaa gtacgctgaa attccagttg
      901 ctgcacgaca ttttttttga agaattccat acaatgtacc aatttgcgca aaagcattac
      961 attagtgaat ctactgctca tcgaaaaatc aatgaatgga aacagcaact gcaaacttac
     1021 ggaattcggc tgcaacgagg tacatatatc gctcaaggcg aagaagaaat cattcgactt
     1081 tacttgcata tgacattctg gcagttgttt cgagggaaaa tctggccatt tgaaacgatt
     1141 tctcaaatgg acgtaaagaa tatggcagaa catatcatgg ctttttttaa tgttcgtctg
     1201 aacgagatca aaaaaagacg attggaatat atgctaggtg cctttttttt aagaaaatca
     1261 cagaagcatt atgttgtatt gaatgagaaa aaaagacggc tgatttctga caatctgttg
     1321 ttccagcgat tttgccaggt catggagccg gtatttccta attattttca agtagaagac
     1381 gagttaggcg cattatttct tgtactgatg actcgtgaag aatattatag tgatcctaag
     1441 atacggaaga aaatttttga ttttcatcaa caagcaaaaa caccgccctt tacagccctt
     1501 tcagaagcaa aagccgctct ttctctttat caggaagagc aggggctgcc agcagaaaat
     1561 ctaaccttcg aggcagaaaa ctatttattc agcagtcatt ttttcgccta tctttttcct
     1621 aatgcgaaag aaacgattga tggcaatagt agtgatttta ttaatcattt agttattgaa
     1681 aacaaggaat tgaaacaatg gctcgtacat ttttttgaaa gtagacacaa acatcccaat
     1741 catctggcat ttaaaaatca tgcgtttttg atggggcggt atctgactgt gtttaaaaca
     1801 ttaggagcct ttactccaca gcttccaaag atcacgatcc ttttaatgac agatttccca
     1861 ttatttgaag agcaactgtt agaggaggga ttacggacat ttttccgtaa tgagtatcag
     1921 ctgatttttc tgccaacaga ttatcggggg agagaagttg atcttctgat ttcgacaagt
     1981 aaagtccacc gcaaaccatg ggcggatctt gactatttta ttgtgactga agaactaaaa
     2041 ttaattgatt acatccaact atctcaaaaa tttgaaatga ttcaaaaaca aaaactatta
     2101 aaacaataac aaagaaggag aaaaaagatg acatttgaag aaattttacc agaattgaaa
     2161 aaaggtgcaa agattattcg taaaggatgg agtggatttg aactttatgt tgttctcgta
     2221 tccgatgatg aatttgatgg ctgtccggtg acgccgtact tattgatcaa aacaagtgac
     2281 gaaggttttt ccagcttcgc tcctacagtt tgtgatattt tagcagatga ttgggcgatc
     2341 gtagaatgaa aaaccagtat ccagatctag ctaaacaggt tgtatttatc acaggagctg
     2401 cttctggaat tggtgctgcg caagcccgag cgtttcttga acaagatgct tttgtatttg
     2461 gattagatca aaagttcggt aaaatggaag aaatttcttt gcgatttcct gaaacttttg
     2521 cctacgcact aggtgatgtt cgacaaatga aagaactcca acaagcggta tcgaaatgcc
     2581 aaaatcattt tggtgaagtt acgattttac tgaatacagc ggggatattg gatgcctaca
     2641 aacccttgat ggaaactgac gaatcgctgt gggatctgat ttatgagacg aatgtgaaaa
     2701 gcatgtatca gctgacaaaa atcatccttc ctgatatgat ccgccaaaaa agcggaacga
     2761 tcatcaatat ggcttcgatt gctggcttga ttgctggtgg aggtgggatc gcttatacaa
     2821 gcgcgaaaca tgcgattgtc ggatttacca aacaactcgc tctggattac gcaggacagg
     2881 gtatccgagt aaaaggaatt gctccaggag ccatccaaac accaatgaat gcggctgatt
     2941 ttgaagggaa aggtgagatg gcagagtggg tggcaaatga aacaccagtc aagcgatggg
     3001 cacagccgga agaagtagct gagctgacgt tatttcttgc ctctcctcaa gcaagctaca
     3061 tacaaggaac gatcatccca atcgacggcg gatggttgtt aaaataacct tgtgtttttt
     3121 tcaagcttct gtatgataaa actaaagaga gaaacaacgg ttgatgataa aaaaagtcga
     3181 tgactgttcc cgacattcga tgccgaacag ccagttcaaa aaattctttt taataatcgt
     3241 taatattcga aactaagcgg cttttcacga cctcttgata taaacgatat tcaaaagctt
     3301 gcaactgcgg taacaagtcc agccaaatga aaaatataag gagctatttt tatttgacca
     3361 ttcttattac ttgttgcagg gcagcttttt cactaccttc tgcgacactt cagttggaat
     3421 tttcttccca tcctttggtc gcggtcatta ccaagataaa attatcttgc aaaggagaaa
     3481 tagaacatgg aaaaaaataa tacccgttca gccaaacgct ggacaacgac agatgtgact
     3541 cggatggcgc tagtcactgg tttatatgtg gcagtgacgc tggttttgtc tgtctttagc
     3601 tttggagtga ttcagattcg tctctcggag atgttcaact atctgtcctt gtataacaaa
     3661 agatacatcg tcgcggtaac agcgggagta gctttggcta atattgcttc tcctcttgga
     3721 ctgatagatg ttgcagtagg aagcgtcagc acgctgcttg tattgcttat caactataaa
     3781 atcactagtc gcatcaaaaa catgaaaatc aaaatggccg tgacagcatg cgtatttgct
     3841 ttttccatgt ttacagtagc tggtcagcta acgattttat atcaactacc ttttttcttg
     3901 aattggtggg tgattgcttt aggagaattg gcatcaatga ttgtcggtgg gataattatt
     3961 tattggatcg gtaaaaaagt ggatttgtca aaataaagat ctgtttaatt taaaataggg
     4021 cagcatggaa gagactgaat gttgagtctt cttccatgct gcttttttga ttaatttgta
     4081 tgaagaaatc gatttagccg ttttttcatc aagataccga tataagctgc tccagttgcc
     4141 ttgattgctt ccggcagtaa aaacggcagt agtccactgg caaatgcagt tgtaaaagta
     4201 agatcaccac ttattttcag ccagatcgtt ccgcagatca atgcagcaag agagcccatt
     4261 agattggcaa agattgcata taagtaatga gcatccgttc tttcgatcat ccaaccagtt
     4321 atccacgttt gtaagagaaa tccaatcaaa tatccgccag ttggcccaaa taaaacagct
     4381 atacctccag tcatccctga aaatacagga agaccaatca agccaagtaa aagataaact
     4441 ccaacagata tcaatcctag ttttcttccg agaaaagttg ctgttaatcc aatagcaaat
     4501 gtttgccctg tcaaaggaac caaaccaaaa ggaatggtca tctgagaaag gacagaaata
     4561 atcgcggcaa attccgcagc aagtatcaat tctttcaatg ttcggttcat aacgccctct
     4621 tttcgttaac ttaatatttt tatttggtta acgaaattgt aaaacaaagt gattactttg
     4681 taaatagaaa atataaaaaa agaccagcta tccaatagat agcggtcttt ttcaagaaag
     4741 cttttgaaat tataagcttt ggttgtagta ttcaacgaca agagcttcgt cgatttctgg
     4801 atatagttcg tcacgttctg gtaaacgagt caatgaacct tccaattttt cagcgtcaaa
     4861 gcttacgaat gctgggcgtc caacagttgc ttctacagct tcttttactg ttacgatgtt
     4921 ttgtgatttt tcacgaactg agatcacttg acccacttct acgtggtatg aagggatatc
     4981 aacgcgtttg ccatcaacta aaatgtgacc atggttaact aattgacgtg cttgacgacg
     5041 agtcgttgca agtcctaaac ggtaaacaac attgtctaaa cgttgttcta gtaagatcat
     5101 gaagttaaca ccatgtttac cttctttgat tttgctagct tttacgaaca agttacggaa
     5161 ttgacgttcg ttcattccgt acatgtgacg aagtttttgt ttttcagtta attgcatgcc
     5221 gtattctgat tgtttgccac ggctattagg tccatgttga cctggtgcgt aagggcgacg
     5281 tgctaattct tttcctgtgc ctgacaatga gatgcctaag cgacgagaaa ttttccatga
     5341 tggtcctgta taacgagaca ttaaaatttc ctccaatgaa tataagtttt tggagtaaaa
     5401 taatccgttg aaaaattcat aatcatatag tttgttcttc aatcttcacc tttgcagccg
     5461 cggttacaca atcgaacccg agacggggca acaaactagg gatgagttat tatttttctg
     5521 ctgcattatt ttacacaaat tacagtatat gatagatcat ccacgaatgt caagataatt
     5581 agtacataaa aacgctttac aaacctaggc tgtctttata aaatgagagg gtatgtgcaa
     5641 atggaaaaaa gcgaaggaag tttaaggaga aaatcaatga atccggtatc accattattt
     5701 gagaaaatcg atgcttcaat tgaaaagaag gcgaatcttt ttgaaaacag cttttcacgt
     5761 tacgctgttc gagcggttct cgcctgtttg tttttgactt taggaacggc tgtggcattt
     5821 gcgatcgcga tgaaggggga agatatcgcg catggtctag gaaagatttt atacgcattt
     5881 atgttcagct ggggtctggt catgattcta tacatgaacg ccgaattagg aacatcgaat
     5941 atgctttata tgaccgtggg tgtttttcgg cagagacttg ctttaagtaa ggcagccaag
     6001 attctatttg cctgtatttt tttcaatatg attggcggta tattatgtgg atttctaatt
     6061 tctatgacta cgccatttca agatttaacg ttggacaact ttatgttaga atcaatagca
     6121 gtaaaactag caaaaccttc agcaacgatt ttggtggaag ggatgtttgc gaatatcgtt
     6181 gtcaataccg ctgtactgat cagcatgcgg atgaaagagg atgtcggaaa agtgatcaca
     6241 gtcgtattca tcattttcat ttttgctttt ttaggatatg aacacgtgat agcgaatttt
     6301 cctgccttta cgcttactta ctttgcttct cacggacaga tggatggaat gacagtcagc
     6361 aatgtgttac ataatttgtt ttttgctttg gcaggaaatt atattggtgg cggtttagta
     6421 atgggactgg gatatgcttg gctgaatcag tcaaaatcat cctatgtgga ctaaaaagtc
     6481 gttcattaaa ggggaagtgc catggaagtt ttagtttttc caaaaaatga ggaaaaagcg
     6541 ttacaaatgg aaaagtacat gaaaaatctt ttttcctttg ctggagtacc taagccggaa
     6601 cgcgctcttt tacaacaacc gttactggat gagagcaaaa atttatctat ttctgaagtt
     6661 ttagcttttg ttcattatta ttatgaacaa atcgaaagag agtatcagta tgtagcgatc
     6721 gatttagtcc agaaaaacat caaacggctt acatttgaag acttagtcgt attgttgcca
     6781 ctagttcaga aaaaagaatg gtgggacagc atcgactctt ggagaaaagt atacagcaca
     6841 tggtgtaaag cctacccaga gcagcgtgaa gaagtctttc aattgtttga aaaaaaggaa
     6901 gatttttggc tacgtcgaat agcaatcacg ttgcaattag gttataaaca gcaaacagac
     6961 acaggactat tgatccgagc aatagacgaa gatcgtcaaa caaaggaatt ctttatccaa
     7021 aaagcaattg gttgggcatt acgcgattat agtaagaccg atgccgattg ggtaaaaaga
     7081 cagctgacaa cagatttgag taagttagct gttcgagagg caagtaagta tttataagaa
     7141 agcgagacga caagagatga gacgcaaatt atttgctttt gatattgatg gaacgttgtt
     7201 agattcaaac aaacaagctt tagatagcac aagagaagca ttggaaaaat tacgcaaagc
     7261 cggtcatctg gtcacgattg ctacagggcg gagccgattt catgcgcaag agatcattcg
     7321 cgatcttgat tttacgaact acattttatg taatggagcg gccggttttt tagaccatga
     7381 acaagtatat aagaatttac tagatcgcga ccagttggat gcgttcgttc aagaagcgca
     7441 tcatgagcag atcgatacag cttttgtcag cttagacaat atcaagcgtt cttcttccaa
     7501 tgatgtaacg gtgatggaag aagcgatgca ttctttcggt gctgtcttgc ctgaattaga
     7561 tcagtttttt gcagaggaac aagaaatata ccaagcgtta gcatttttcg atcaaacata
     7621 tgatgggaag ttctcttcat atgataaaat tcgatttgtc cgctggcatg agaacagtgt
     7681 agatgtcgta cctaaaaatg gttctaaagc agcgacaatt ctgcacttag cagaacaagt
     7741 aggcatccct catgaagaca tcatcagctt tggcgatgga caaaacgacc gtgaaatgtt
     7801 gcgcatgtca ggaattggga tagctatggg gaatgctgtg ccagaagtac aagcagaagc
     7861 taagatggtc actgatacaa acgatcagga tggaatttgg aaggcattga aagagttaag
     7921 cgtgatttaa aagaggttgt gaaaaagctg ttctgcatca agtaataagc ccagccaaac
     7981 aaaaatagct cctcctattt ttcgtttttc tgggcttatt accgcagatg caagctttcg
     8041 aacaccgttt aaggaagagg tcgtgacaga agtggtcagt ttcaagaaat aagaagggat
     8101 ttacgaaaat tgcttctcaa atttttgtaa aattacggct tatttctgaa gaagtagatg
     8161 aaacaacgtt tattcgggaa atgggactgt gacaagatgt ttgtcatagt cccatttttt
     8221 tattttattt ttcaaaacta agaaatacca ggaaagagtt ccttttgttt gaccttttct
     8281 ttcttattga aaacaactat aatatagagt gatgttaaaa gagaagagga atttagtgtg
     8341 cgggtattgt ttattggtga tgtagtaggt tcaatgggac gagagatgat tactgaatat
     8401 cttcctagat tgaagaagaa gtaccgtccg caagtaacga ttgtaaatgg tgagaatgcc
     8461 gcttctggac gtggaatcac agaaaaaatc tataaaaaat ttttgcaaga cggcgtagat
     8521 gtcgtgacga tggggaatca tacgtgggac aaccgcggaa tctttgagtt tgtaaatgaa
     8581 gctaaaaaga tggttcgtcc ggcaaatttt ccggaaggga cgcctggaca agggatggtc
     8641 tttgtcaaag tgaaccaagt cgaactggca gtgatcaaca tgcaggctcg ttcttttatg
     8701 gtggacttgg atgatccttt tcgtaaaatg aatgagctgg tagaagaagc cagaaaacgt
     8761 acgccgatca tttttgtaga ttttcatgga gaaacaacaa gtgaaaaaca agcaatgggc
     8821 tggtttttag atgggaaagt ttcagcagtg gtcggtacac atacacacgt tcagacaaat
     8881 gatgcgcgaa ttttgccaag aggaacagcg tatctgacag acgttgggat gacaggtccc
     8941 tatgatggta ttttgggtat gcgcagagaa cctgtaatcg aaaagtttct gactgcatta
     9001 ccaaaacgtt ttgaagttgt ggaacaaggc cgatcgattt taagcggctg tatcttggaa
     9061 ttggatgata cgacaggtca tgcaaaagaa atccagctga ttcagatcaa cgatgatcga
     9121 ccgttcatgg agtagaaaga gaggcagttt tttgcagcag gagccggaaa ttcaaaaaga
     9181 agtaaggaaa ctgacaaaac ttttaagaga gaatgaaacg atcattcgct acaaagaact
     9241 tgaagaaaag atccagcaaa accagtattt agctgagttg agagaaaaaa tcaaacaagc
     9301 gcaaaaagat gctgttcatt ttgcccacta tgacaaacca gcagcagaaa aagaagcaat
     9361 caaacaagcg gatcaattca tgcaagaatt tgatcagcat ccgcttgttg tagcttatag
     9421 aaaacagctg ttggaagcag atgatctgct tcatcattta acaactatga tacaagaaga
     9481 aatcaatgga caaatagagg aggaaaaaca tgcctcaaaa aactaaaaat actcctatga
     9541 tggaacaata tctaagcatc aaggcccaat accaagatgc ttttttgttc tatcgtttag
     9601 gagactttta tgaactattt tacgaagatg cgatcaaagc gtcacagctt ttggaattaa
     9661 cgttgacgag cagaaatcga aatgcagaag aacctattcc tatgtgcggt gtacctcacc
     9721 atgcagcaca aggatatatc gatgccttga ttgaaaaagg ctataaagta gcgatttgcg
     9781 agcaggtaga agatccaaag acgactaaag ggatggtcaa gcgcgaagtg atccagctag
     9841 tcactcctgg tacagtcatg gacagcaaag gattgtcggc aaaagacaac aattttttaa
     9901 cagctgtagt tagtcaagga aatgaatttg gctttgctta tgccgattta agtacgggag
     9961 aattgaagac ggctcggttg catgatgaag aagctgtttt aaatgaagcc tctgcattgc
    10021 agacaaaaga actcgtatta ggcagtgaga tcactgatac ccttcgtgaa cagctaagcg
    10081 ggcgtttagg gctagtcttt tctcaacaaa atgagatgga agaaaacgcg gaatttagct
    10141 ttttgacaag cgaactagtc gatccgctgg aaaaagaagc aaccggcaaa ctattgactt
    10201 atttatcggt gacacaaaag cggagtttag ctcatatcca aaaagcagta gaataccaac
    10261 cagatcattt tttgaaaatg gattattatt caaaattcaa cctagaatta agccaatcta
    10321 ttcggactgg gaaaaagcac ggcactcttc tatggttgtt agatgaaaca aaaacagcaa
    10381 tgggtggccg tttactaaaa caatggctag accgtccgct tatccaggca aaacaaatta
    10441 aagcaagaca agaaatggtc gcttctttgc tagacagcta ttttgaacgt atcgatttgc
    10501 agtcagcatt aacgaaagtc tatgatctgg aacgcctagc aggtcgagta gctttcggta
    10561 atgtcaatgg gcgagacttg atccagctga aaacttcttt agaacaagtg ccaatgatca
    10621 gagggttgat tgaaggaatc gatcaaggtc aatggcaaag tctgctttca gaaatgcagc
    10681 cgatggacca tctcgtccaa ttgatcgacc aagctatcca agatgatccg ccgttacaaa
    10741 taacggaagg aaacatcatc aaagatggat tcaatgagca gctcgatatg taccgttctg
    10801 ctatgagaaa cggaaagaaa tggttggcag aacttgaagc aaaagagcgt caagaaacag
    10861 gaatcaagaa cttaaaaatc ggatttaacc gcgttttcgg ttattatata gaaattacaa
    10921 aagcaaatct tggaaatgca gaactggaga agtatgaacg aaaacaaact ttagcaaatg
    10981 cagagcgttt catcacacca gaactaaaag aattggagac acaaatcctc gaagcagaag
    11041 aaaaatctgt tgatttagaa tatcagttgt ttttagctgt gagagaagaa gtcaaaaagg
    11101 ctatccagcc gctacaagta cttgcaaaag caatcagtgc agtagatgtg ctacaaagtt
    11161 ttgcaacgat cagcgaacgc tatcagtatg ttcggccaga acttgtcagt gacaagcatc
    11221 agcttctgat caaagacgga cgacatcctg tagtagaaaa agtattagga catcaggaat
    11281 atatccctaa cagcgtagaa atggcagaag acgaaatgat cttgctgatt acaggaccga
    11341 atatgtctgg taaaagtacg tatatgcgac agttggcatt aactgttctg atggcgcaaa
    11401 tgggctgttt cgttccggca aaacaagcag ttttacctat ttttgatcgg atttttaccc
    11461 gaattggtgc aagtgacgac ttaattgctg gacaaagtac ttttatggta gagatgatgg
    11521 aagccaatca agccctgcgt tatgctacgc caaacagttt gattttgttt gacgaactag
    11581 ggcgaggaac agcaacctat gacggaatgg cgttggccca agcaatcatc gaatatatcc
    11641 atcgtcatgt acaagcaaaa acactctttt ctactcatta tcatgaactg acggtacttg
    11701 agaaagaact tccgcagctt aaaaatgtcc atgttggagc cgttgaaaaa gacggagaag
    11761 ttgtcttctt gcataaaatg atggatggac ctgcggataa aagctacggc atacatgtgg
    11821 caaagatcgc aggattgcct tccaatctac tagaacgagc agcagatatc ctgcatacgc
    11881 tagaaaatgg cgataacgga caccatactg ttccagctga agtagaagag aaaactaaaa
    11941 cagccaaaca ggagcaaata aaaccacctg cagaaaaagt aaatcaagac catatacaag
    12001 accgtgtaaa agaagaaaac caacagcttt ctttattcag tgaattatcc gaaaatgaaa
    12061 cagaagtcat tgaatcactg aagcaaataa atttactaga aatgacgcca atggatgcac
    12121 taaacacatt atatgaatta caaaaacaac tgtaggaaga aggcggatat cgatggccaa
    12181 aatccaagaa ttatctgaac gtttagctaa tcagatcgct gcgggagaag tagtggagcg
    12241 accagcttcc gttgtgaaag aattagtgga aaatgcaatt gacgccggca gtactcagat
    12301 tgatatctta gttgaagaag cgggactgcg gacgatccaa gtgattgata acggagaagg
    12361 cattttggca gacgacgtag agaatgcctt caagcggcat gcgacaagta agatccataa
    12421 tcgcgacgat ctttttcgca tacgaacgct gggctttcga ggggaagctt tgccaagtat
    12481 tgcctctgtt tctgaaatga ctctggaaac ggcgaatcag gaagaaaaac aaggcaccta
    12541 tctgtcgctg aaaggcggag aagttattga gcatcgacca gcaccactgc gtcaaggaac
    12601 gaagattacc gtcagcaatc tgtttttcaa tacgccagcc cgcttgaaat acgtgaaaac
    12661 actgcacaca gaattagcga acatcgggga catcgtcaat cgactggcat tgagtcatcc
    12721 atcgattgct tttcgtttag tacatgatgg aaacaaaatg ctggcaactg ctggaaatgg
    12781 cgatctgaaa caaacaattg cgggaatcta cggattatct accgcaaaaa aaatgctgaa
    12841 aatcgaagga aaagatctag attttgagtt atttggctat gtttcattgc ctgaggtgac
    12901 tcgtgccagt aggaattact tatcgacgat catcaatgga cgttttatca agaacttttc
    12961 cttgaataaa gcaatcgttg caggttatgg gtcaaaatta atggtcggtc gtttccctat
    13021 tgctgtattg gaaatcaaaa tggacccgct tttagtagat gtaaatgttc atccgacgaa
    13081 gcaggaagtc cggctgtcga aggaaaaaga actaacagag ctaattagta acgccattca
    13141 aaaagcattg tctcaagaaa atctgattcc aagtgcagcg gataatctac ggtttaagaa
    13201 aaaagtacct gatcagccta aaacagaaca aatcgaaatc gatttgtcct acgcttttga
    13261 agaagaaaaa cctaaaaagc caagtagttt gaattttgat cgagagacag gtaccttttt
    13321 cgtagaagaa ctaaagaaca catttgttga cagaattgtt gataagtctg tggaaaatgt
    13381 tgaaaactat tctggttttt ctgaagaaaa caccacttat ccagaaaaaa cagcgaaaac
    13441 ggtggataag tttggtgaaa atgttgataa ctttgtagaa aaaacagtgg aaaaatctga
    13501 aaagaaagaa tttcccattg tggataacat ggagaaaaca aatgaagaac aagcagataa
    13561 atccgtagaa gaggatgaaa agatttacga ggaagaattg acactccatc ctgaatttga
    13621 tttcactcaa ggaaacgaca aaacattaga acaagccatc aagaaattag aaacggaaaa
    13681 accagtacaa cgttttcctc agttggaata ttttggacag atgcacggaa cgtatctttt
    13741 tgcccaaagt agcgatgggt tgtacatcat tgatcagcat gctgcccaag agcgcattaa
    13801 gtatgaatat ttccgggaaa aaattgggga agtatctgat gatctgcaag aattgcttgt
    13861 tccatttgtg ttagactatc caaacagtga tgctttgaaa ttaaaagagc aaaaacactt
    13921 gctagaagat gcagggattt atttagaaga atttggtcaa aacagcttta ttgtacgggc
    13981 ccatcctact tggtatccca atggagaaga agaatcgatt attcgggaga tgatcgatat
    14041 gctgctgaca actggaagtg tgagtgtaaa aaaattccgt gaagcaacag caatcatgat
    14101 gagttgcaaa cgatcgatta aagccaacca ttatttgaat gaagcacaag cacgtgtgct
    14161 gctgaaggat ctggcacgat gcgaaaatcc tttcaattgt ccccatggcc gtccagtatt
    14221 gattcacttt accaattcgg atatggaaag gatgttcaaa cgaatccaag acccgcatta
    14281 agtcaaagag aagagggaaa acatgaagat tgtattagca tcccaatcac caagaagaaa
    14341 agagttattg gctcatatcg tttcagaatt cgagattgaa cctgctgata tcgatgaaac
    14401 gccatttcca gacgaacagc ccgtcgatta tgttcgtaga atggctgaag aaaaagcacg
    14461 aactgtctgg gaacaagatg aaaaagaaga ccatttagtg attgccagtg acacgactgt
    14521 tgttctcaat caagagatca tgggtaaacc agaagatctg gctgaggctg aattcatgct
    14581 gaaaaaacta agcggggaaa cacatactgt atatacagct gttgttttaa aaacaaagga
    14641 acgagaagaa cggatactag cagaagcaca tgtcactttt tatcctttga cagacgaaga
    14701 gatcaaacgc tacttggaga cgggggatta tgcggataag gcaggggcat acggcatcca
    14761 aaatgctgcg agtgtattcg tcaaagaaat ttctggagat tattacagta tcgtaggatt
    14821 tccgattggt gctgtcaatc aggcactgaa aacattcatt taaacaaaaa agcggactat
    14881 ctgattttcg attgaaaatc catgatagcc cgtttttttt attgaaaaga ttacttatct
    14941 actctgacta agattttact tcagctttac cgactgcttc gcccgggcga acaagtcctg
    15001 attggtcaag agaaagtcct gcaacttttt cattattggt caaagcaaca ataatgtcag
    15061 ttttcttgcc agcttgttct atttctggca aatccatttc agcaatcagg gtctctggtg
    15121 tgacaaggta tccttctttc acgaatacat tgaaaggaac accctttagt tcaacagtat
    15181 ctaatcccat gtgaacaagt acttccagcc cctcattaga aagaatacca atggcatgtt
    15241 ttgtttcaaa gacactcgtc actttaccgt ttactggtgc atagactttg ccgtttgacg
    15301 gttcgacagc ataaccgtca cccatcattt tttgtgagaa aactgggtca tttacttcag
    15361 ttatttcctt gatggtccct gcagcgactg cgaataatgt ttcttttgtt gcaactgccg
    15421 taccagttgc tgaaacaggt tcgaaagact gtggcgttgc tgttgcgcca tttgctgttt
    15481 gaagttgtac atcagcagca ttttcaggaa cagcaggatc aatcttattc aaaattccct
    15541 gacgtctaaa gatgatcgtc aagccaaatg gaatgatgac agcaatgatc attgcgatga
    15601 tgaaaggtac ccatgtttct gcttggatag ctagtattcc tggcaaaccg cctactccga
    15661 tcgcgttagc tcgaacaccc atcaagttag caaacatgcc agctaatcca gagccgacca
    15721 ttgcagcgac gaaaggatag acgtatttca aattgattcc gaacatagca ggttcagtta
    15781 cgcctaagta acaagaaatc attgctggaa tcgagatttg ttcttctttt ttattcccac
    15841 gatgtaagaa gatgatggct aagactgcag agccttgggc gatatttgat aaagcaatca
    15901 tcggccataa attcgttgat ccgaaatctg caatcagctg catatcgatg gcattggtca
    15961 tatggtggag accagtaatc actaaaggag catacaggaa tccgaatacg gcactaaaca
    16021 accagctgat agaagacgtc aatccagtat ttacgatatt tgagatccag cttccgactg
    16081 tccagccgat aggacctaaa ataacgtgtg cagctaaaac agttggtaac aatgaaaaca
    16141 atggaacaaa aatcatcgag atcgactgag ggatatattt gcggaagaag atttctagat
    16201 acgctaacat aaaccctgcc agcatggctg gaataacttg cgcttgataa ccaatcatct
    16261 ggacttgagc aaaaccaaaa tcccaaaatg gaatatctgc tgcggctgtg gaagctacac
    16321 tataagcatt taataattgc ggagaaacta acgtaattcc taaaacgatt cctaatattt
    16381 gtgtagtacc catctttttt gcaatactcc aagtgatacc tactggaaga aaatggaaaa
    16441 ttgcttcacc cggtaaccac aaaaaggcat tgacaccatt ccaaaacttc gagtgttcaa
    16501 cgattgttcc accaagactt tcaaactgga taccttcaag tacatttctg aatccaagga
    16561 tcaatccacc gacaatgatt gcaggaatca gtggtgtaaa gatttctgct aaaacggcaa
    16621 tagcacgttg aacgggatga aggttttgtt ttgcagctgc ttttccttgt tctttggaaa
    16681 ccccttcaac tccagatact gcaacgaagt cgttataaaa agtagaaaca tcgtttccta
    16741 tgatgacttg gaactgtcct gcattcgtga acatcccttt tacgctaggt atatcttcga
    16801 tcgctttttc gtccgctttt cctggatcat tcaggacaaa acgcatacga gtcgcacaat
    16861 gactaactgc agcaatattt tcttttccgc cgatatcatg taacagcttc tcggcatctg
    16921 cttgatattt tgccatatca ataaacccct ttctcttaac ttgtctatgc aagttgtttc
    16981 ttcatttact atactttttt tcggagagaa ttgcaagcgt tttattaaaa agtacgagag
    17041 aaaatgatat cgttttaaaa agcttaaaat aagcttttct taaaaatagg aacattgaaa
    17101 tacaaaaaga gctgtagtat agtgaagaaa tgatggaaga acgagtgagg gaaaaaacat
    17161 gaataagttc aatgaaattt ttttagattt ggaacagaaa attttagcga aagaatatcc
    17221 tccgcattcg cttttaccca gtgagaacca attgatcaaa atttatggtg tttcacgaga
    17281 aacaattaga aaagcgctga atcttttgac tacggaaggt tatattcaaa aaaaacaagg
    17341 aaaaggttcg atcgtactgg atcggaatcg cttcgacttt cctatttctg gattgactag
    17401 ctataaagag ctacaggaga cccaacgtat tccaagtgaa acgatcatcc atacgttaga
    17461 agaaacagaa gtgacaaaag cattgaacga gatcactggc tgggagatcg gtgcgcctgt
    17521 ttggcatttg atacgcgaaa gaaaaatcaa tggcgaagta gttatattag acaccgatta
    17581 tctattaaag gaaatcgttc ctattttaac tccagcacaa gcacaaggat cgatctatga
    17641 atattttgaa aatgagcttt ctttgacgat tgcttacgcg caaaaggaga tcacagtaga
    17701 agaagtaacg gaaatcatga aaacagcgat ggatcttcac gatgacactt atgcagtagt
    17761 agtcagaagc ctcgttcatc tggaagatac ccgctgtttc gagtattctg agtcggttca
    17821 ccgattagat aaattccgtt tcgttgagtt tgcccgacgc cgaaaagtgt aaatagttca
    17881 aaagaaagca aattgttggc atctgtccac tttggcgcta tgataggatc acaaaggggg
    17941 catttttaat ggataaacca ataagaccag aaaaagaaga actgaaagaa aagttatcac
    18001 ccatggctta tgcagtcaca caagaaaatg caacagaacg accatttagc gggaaatatg
    18061 atgattttta cgaaaagggg atctatgtag atatcgtcag cggtgaaccg ttattcagct
    18121 ctgcagaaaa atatgatgca ggttgtggct ggccatcatt cagcaaacca ataacgaaaa
    18181 gacaagtgcg cgaaaaagcc gatttttctc atggcatgca tcgaatagaa gttcgaagca
    18241 aagaagcaga ttctcatctc ggacatgtgt ttaccgatgg accagtagat caaggtggtc
    18301 tacgttactg catcaattct gcctcactga aattcattcc atatgaaaag atggatgaat
    18361 taggttatgg ggaattcaaa tcacttgtag aataatggaa atacacaaag agcggtacaa
    18421 tacggggatt tactcgatcg tccgctcttt ttttattcaa gcgattgcta tttgaaagaa
    18481 acgctcccta gactcctttt ttcacaaggt gaaatgtgct acaataaagg gaacgtatgt
    18541 gtgcaaaaga aagaggacta gaatatgtat gaatatctga caggtgtggt tacctttatc
    18601 aacccctatt acatagtagt agaaaccaat ggtatcggct accagatcgc actaggaaat
    18661 ccttaccgct acagtagcaa actaaatcaa aaaataaaaa tttatgtcca tcaggtaata
    18721 cgtgaagatg cgcatcttct gtatggattt gattcgctag aagaaaagca actgtttttg
    18781 cgattagtaa gtgtttcagg aatcggtccg aaaagtgccc ttgcaatcat ggcaagcgaa
    18841 gaccactccg gtttgattca agcagtagaa tccagtgatg tcacttattt gacgaaattt
    18901 ccaggagtag ggaaaaagac agcacaacaa atgatcttgg atctaaaagg aaaattcggt
    18961 gagctgagta tcgatacacc ttttagtcta tttgatgaag caaacacaaa agacgctaca
    19021 gctctatctg aagcaatgga agctctctcg gctcttggtt acagtgatcg agaaatcaaa
    19081 cgtgtagaaa aacaattaaa agaagtagat aatcagacaa cggatgagta tctacgccaa
    19141 gcactcaagc taatgatgaa aaaataagga ggagaccaaa tgacagatga atacttgtta
    19201 tcaccagaat ctggcgaaaa tgaactgagt ttggaaaaat ctcttcgacc acagctgctt
    19261 tctcaatata tcggacagag aaaagtcaaa caagaacttc agatttacat cgaagctgcc
    19321 agaaatcggg aagaaccttt agatcatgtt ctgttgtacg ggcctcctgg attaggaaaa
    19381 acgacgatgg ccatggtcat tgctaatgag atgaccgtaa atattcgtac gacgagtggc
    19441 cctgctatcg aacgtccggg tgacttagta gcaatcttga atgaactgga agcaggggat
    19501 gtcctgttta tcgatgagat ccatcgatta cctagagtgg tagaagagat gctttattca
    19561 gctatggaag atttctatgt agatatcatg gtaggacaag ggccaaccgc acatccggtt
    19621 catttccctc ttcctccctt tactttgatt ggcgcgacga cacgggcagg tatgctttct
    19681 gcacctttac gagatcgatt tggcatcatt tctcatatgg aatattatga cgaacaggat
    19741 ctgcaggaga tcgttttacg ttcttcggat atttttcaaa cagagatcat tgaagaaggg
    19801 gcattggaaa ttgctcgccg atcacgagga acgcctagaa tcgctaatcg cttgctcaaa
    19861 cgggttcgtg attttgcgca agtccaagga gacgggaaaa tcgatcgtcc tatagcggat
    19921 caggcactta ctttgctaca ggtcgatcag gctggattgg attatgttga ccagaaattg
    19981 ttgcgaacaa tgatcgagtt atatggcggc ggaccagtag ggttaagtac gctttcagta
    20041 aacataggag aagagcgtga gacggtagaa gatatgtatg aaccgtatct gatccaaaaa
    20101 ggatttttaa agcgtacacc tagagggcga attgctactg cttatgccta tgaacatttt
    20161 ggttacgact atcatatatg atttttgctt ttagattgga ggaaaatgaa tgagtgatac
    20221 aacacgtacg aaacaattga tcaaaaacgt attgattgat ttgtgccaaa cgcaatcttt
    20281 tcgaaaaatc agcgtccaaa aaatcgcaaa cgaagcaaaa atcaatcgac aaacatttta
    20341 ttatcatttt acagataaat acgatttgct tcgttgggtc tattgtgagg atgcattgca
    20401 ttatttagat ccacaatgtc tttcacttga taattgggaa gagcaagcat tgaaaatgct
    20461 gaaagcaatt gctgagaaga aagaatttta tgcaaatact gtgctttctg acccagaaat
    20521 tttacaaaaa gagttttctc aactgatcca aaaatcattt atcaagattt ttgaacaaat
    20581 ggatgaagaa agacaacttt ctgcaagaga caaactattt tatgctcgtt ttttttctta
    20641 cggttgcagt ggtgtattag tcaattggat cacgaatgaa tatgaagaaa caccgatgga
    20701 aatcgctatg cagcttttcc gtttagccaa ggatacggaa ttatattctt atcgtcttta
    20761 tgcaaaagaa gagttggaag aacagtaata gaaaaatttt ttgttggaaa agcaataatc
    20821 gctaaaagga gatggggaaa tgacaaaaat tttatttgtt tgtttgggaa atatttgccg
    20881 ttcaccgatg gcagaaggct tgctgagaaa acgaatagca ttagaaggaa gggaagcaga
    20941 attttttgtg gattctgctg ctacaagcac gtatgaagtt ggaaagacac cgcaccctgg
    21001 aacgaaaaaa atattaaacc aagaaaaagt agatatgacg aatatggttg ctcggcaaat
    21061 cacaccccac gattttgaaa cttttgattg gatcattggc atggatcaag aaaatgtaga
    21121 agaactgaaa cgaagagcac cacgctcagc gcaggggaaa atccatttgt ttttaagtag
    21181 cattcctgga aaagaaaaag aaaatgttcc cgacccatac tataccaata actttgatga
    21241 gacatatcac ttgatcacag aaggcctgaa tcattggtgg aatatttgga ttgatgaaaa
    21301 taaaataaca aacaatttgt aaagttaacg ctttcttttt aaggcgatgt tagagcattt
    21361 ccttgttttt ttgtaaaatg ttaggtaaaa taaaattaat taagtaacac tttcttagct
    21421 aaaggaggag tgcattcgat gaacgaagag acagtatcgc caatgaagaa gcttacgaag
    21481 ttagttactc atacttcgta tcaacttttt gattcttttg taaatgacac tgaagaacat
    21541 gctaagaatg tacgattgca aggaaagttt attcttgagc tgcaaaaagc tgctactgaa
    21601 catagtctag ttatcttaca agtaagagca aatcgtttga gtagcaagta tgaaacgatc
    21661 tcaggctggg tggcgacaaa aacggtcgaa aaagaccgag tgatgatccg cctacaaaac
    21721 gaagagcagc agatccggat ggttcctgta gaacaaattg aaaaaataac aatcctttca
    21781 ccagcagggg aacaggaacg gttatcaaaa taatttatac cagatagaaa agcacgtatg
    21841 agcttgtacc atcaatcatt actaatcaaa aataaccgaa tgctttaagc tgatatcagt
    21901 aaaacggaac gttttaggat gagtatcata gcatgacagc attcggttga ttagttgaat
    21961 cgattggatg gtacaagttt ttttgataaa aaaaggtcct gctagccggg gagctagcag
    22021 gataaggagt taaaaatgaa aaagtgttgt tagggttgtt tgttggtatg cttatataat
    22081 agtcattagt tgtgaatatt ttgtgacgaa agttttcgaa agttgttaag tt
//
LOCUS       DARPZJ010000041        21503 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.042, whole genome shotgun sequence.
ACCESSION   DARPZJ010000041 DARPZJ010000000
VERSION     DARPZJ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.042"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            5..403
                     /locus_tag="SLE23_001904"
     CDS             5..403
                     /locus_tag="SLE23_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEI8468805.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="SLE23_001905"
     CDS             387..1082
                     /locus_tag="SLE23_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEI8468806.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1666..2553)
                     /locus_tag="SLE23_001906"
     CDS             complement(1666..2553)
                     /locus_tag="SLE23_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEI8468807.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2738..3577
                     /locus_tag="SLE23_001907"
     CDS             2738..3577
                     /locus_tag="SLE23_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEI8468808.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3773..4747
                     /gene="sgrA"
                     /locus_tag="SLE23_001908"
     CDS             3773..4747
                     /gene="sgrA"
                     /locus_tag="SLE23_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HEI8468809.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5045..5401
                     /locus_tag="SLE23_001909"
     CDS             5045..5401
                     /locus_tag="SLE23_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468810.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5404..6561
                     /locus_tag="SLE23_001910"
     CDS             5404..6561
                     /locus_tag="SLE23_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468811.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6587..7027)
                     /locus_tag="SLE23_001911"
     CDS             complement(6587..7027)
                     /locus_tag="SLE23_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEI8468812.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7187..7693
                     /locus_tag="SLE23_001912"
     CDS             7187..7693
                     /locus_tag="SLE23_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8468813.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7861..9774
                     /locus_tag="SLE23_001913"
     CDS             7861..9774
                     /locus_tag="SLE23_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEI8468814.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9779..10780
                     /locus_tag="SLE23_001914"
     CDS             9779..10780
                     /locus_tag="SLE23_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8468815.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10982..11188)
                     /locus_tag="SLE23_001915"
     CDS             complement(10982..11188)
                     /locus_tag="SLE23_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HEI8468816.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11834..12682)
                     /locus_tag="SLE23_001916"
     CDS             complement(11834..12682)
                     /locus_tag="SLE23_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8468817.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12681..13748
                     /gene="gnd"
                     /locus_tag="SLE23_001917"
     CDS             12681..13748
                     /gene="gnd"
                     /locus_tag="SLE23_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HEI8468818.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13750..14751
                     /locus_tag="SLE23_001918"
     CDS             13750..14751
                     /locus_tag="SLE23_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HEI8468819.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14748..15032
                     /locus_tag="SLE23_001919"
     CDS             14748..15032
                     /locus_tag="SLE23_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HEI8468820.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15065..15862
                     /locus_tag="SLE23_001920"
     CDS             15065..15862
                     /locus_tag="SLE23_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8468821.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15876..16709
                     /locus_tag="SLE23_001921"
     CDS             15876..16709
                     /locus_tag="SLE23_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8468822.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16727..17584
                     /locus_tag="SLE23_001922"
     CDS             16727..17584
                     /locus_tag="SLE23_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8468823.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17606..18115
                     /locus_tag="SLE23_001923"
     CDS             17606..18115
                     /locus_tag="SLE23_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8468824.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18152..18553
                     /locus_tag="SLE23_001924"
     CDS             18152..18553
                     /locus_tag="SLE23_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468825.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18665..19018
                     /locus_tag="SLE23_001925"
     CDS             18665..19018
                     /locus_tag="SLE23_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468826.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19052..19495
                     /locus_tag="SLE23_001926"
     CDS             19052..19495
                     /locus_tag="SLE23_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEI8468827.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19512..20597
                     /gene="uxuA"
                     /locus_tag="SLE23_001927"
     CDS             19512..20597
                     /gene="uxuA"
                     /locus_tag="SLE23_001927"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEI8468828.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20590..21303
                     /locus_tag="SLE23_001928"
     CDS             20590..21303
                     /locus_tag="SLE23_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8468829.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7400 a         3301 c         4491 g         6311 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta cttatttctc atttaaacga
     1201 tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt tttgaataaa
     1261 tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc tctagtataa
     1321 cagaataaga ggaacaagtc cagaagggat atttttagtc ttttttaaaa taacttttca
     1381 gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa aaaataggga
     1441 agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa aaaacttttt
     1501 taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca aataaaaaaa
     1561 ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga atttccaaaa
     1621 atcacttctc aaattttgcc acatccccaa ttgggtcaaa tttgtttatt tgaatatatt
     1681 ttttacataa ggatctttaa tagttacatt gtcttttttc atcactttac ggattgtttt
     1741 atccatgaat tccgtatcaa gagtttttgc ttcggtagca attttttcta gctcagattt
     1801 gtatttgtct ttattagaac ctttatcctg tttttttacc atttttacta gataatagct
     1861 ttgctgataa gtcgttggat ctgttacagg aatgatatca gaaacttccc cgttttttag
     1921 tttaaatgct gcttttttta cttcagtagg aatctctgga ttggttgaat caaaattcat
     1981 ttttccatca gtttccttta atgttttatt ttttccataa gcttgaacaa gcttggagaa
     2041 attttcccct tcatttgctt ctttttttgc tttatctgct tcttctttag tcgaaaatag
     2101 aatgatctgt gtactaactt ctggatagaa ttctttccaa gcagtgtcta gatctttatc
     2161 tgttaatttt acattggctt tcaaaccgta ttggaaagcc agcatctgtt taaagagttt
     2221 cttatatgtc tcttctgttt ggccaactgc ttttaattgt tccttgtagt ttggaccgag
     2281 ttttttgatt tgttcattat attcttttgt tacttccttt gaagaaatct cttttccgta
     2341 tacatcatca aatgctttga agacaatcat tttttttaat agtgtttgat tatttgattt
     2401 aacttttggg ttatcataaa aatcctgaac tgtaagtgtt ccacctttaa acgttgcaat
     2461 cgtttcattg gacttgctac aacctgagaa tagtaaaatt gcacatgctg aaaggcacat
     2521 aattagtagt tgttttttca aaaaatttcc catcctttcc ttattaaaaa cagtctaaca
     2581 gaagaattag ggagacagtc tttcattttc gtaaggttgc tgtagatatt cttagttcgt
     2641 aaaaatctat tctctctatg atggagaaca tttacatagt tttcacgaga caagaaagaa
     2701 aagggttgtt aaacttaata taaaggaggg atgaaagatg atcaggatta ttcggttgat
     2761 tggatctgtt ttaatagtct tagttggttt tgttttagga attcttgtca ataatgcact
     2821 tgcggatatg tttattggaa atagtgaatg gattggagca attgccggta cggtcggaca
     2881 tttagctgtt tttttactag ctttatttct tgctagtaag gtcgaaggaa aaagaataga
     2941 agattatggt gtttctgttc gaggaaaaga ctgggggtat ttagcgggag gtctcgttgt
     3001 tggaattgga gtgtttctgc ttattactag tccattatat ttgacggggg cgtatcggtt
     3061 agattcagga aacgcaaaca ttgtgccgct gataacgagt tttattttat ttattgcagt
     3121 gggggcatca gaagagcttt tattccgtgg cttttttcag catcagatgc ttagatttgg
     3181 tccgttaata gcaatgattg gatctgctgc attatttgct cttttgcacg gattgaatcc
     3241 taacatgaca tttctggcag ttttcaatat ctttttagca ggttgctttt tcagcgcact
     3301 tatctacagt acaggaagtt tatttacggc tattggtgct catattactt ggaattggac
     3361 acaaggagct attttgggta taccagtcag cggaacgcaa gaacaaggtt ttttctccac
     3421 tctgatccaa tcgcaaaata caataattac tgggggaaac tttggggctg aagcatctat
     3481 atcaactaca ttattcttgt tagtcttgat tgttggtttg ttactctatg catataaaac
     3541 aaagcggatg aagaaataca ctgctgttta tcaataaaag atgaagaaag caaggctgat
     3601 atcggtcttg cttttttaag tctgtcattg attaaacgaa aaagtaaaca aattcaagcg
     3661 aatacacgac atcttttgtt agattttcac aactgactgt cgtgttctca tcattttcat
     3721 tttatataat tcctttatca aatagaaggt aattatatgg agagtgatag aaatgaagaa
     3781 aacagcgacc gtattatttg ttattcttgg gctgagtata attgcagcaa tgattggaat
     3841 cagtacttct gcaaatgaac gggcaaatga gaatctttca tttactgtga aaactgatcg
     3901 gattgtttat gacatgacac aacaagtcat tactattcca gtcaaaccaa acaaaagcgt
     3961 gaatgctagt gatgtacatg ctgttctaac atatggttgg gatggtaatg gaagttcaga
     4021 aaaagttatt ggggaagttt atttaaaaga cgtacaatgg accgctggta ttgagtatac
     4081 aataatgatt tctgcagaac tatcgattga tgagatcaag agtaaagata aagttgattt
     4141 gattgttttt tatgatggac agatgacgat cacggagaat ttgaaaccaa gcagttggac
     4201 agttgttgga ccgccaagca gtacggatag cacaagtagt gaaagcagta cagaaaacac
     4261 gagcggtgaa agcagtacag agagtacgag cagtgaaagt agcacagaaa acacgagcag
     4321 cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcacga gcagcgaaag
     4381 cagtacggag agtacgagta gtgaaagtag cacaggaagc atgagtagtg agagtagcac
     4441 aggaagcacg agcagcgaaa gcagcacagg aaaagtaaat aatgaacttg atttggtacc
     4501 tatcatacca actaaggaac aaaagagaaa tgcagggagc aacctaaaaa gtgtgctaaa
     4561 acagcctgat tttgtttctc gtggaattga tcatcaagaa aaagcgaaag aaacagataa
     4621 tagaaaaagc gatttaccag aaactggtag tagaaccttg aacaagctaa ttacatggat
     4681 gggtgtgtta ctcattttga ttgtaggagc aagctatttt cgttctctct tccatcgagt
     4741 gaaataaaga ataaaagcaa cagatctaaa attgaataaa acgatagatt tttgagtgaa
     4801 tatttcattc gagagtgctg tattgcctgg cgaagttgta gctttgccag atctattttt
     4861 gtttactaac atatttgaga aacaggaaat aacaggaaca caaatggaaa ataagagcaa
     4921 gaataattga caatgcacac tgcgcatggt agtatctctg aaaaatcagt aacgaatcta
     4981 tttgtacgtt attcatgtag ctgtcggaat aagtctaaat aatagataaa aaggagtatg
     5041 tactttgttt gaagaattta ttgatatcaa tgaaaggcaa gtatatcaat ttttgaacta
     5101 ttgttatgaa agagacgaga aattatatgt ggtgaaggat atcgctttag atctaaacta
     5161 caccctggct aagatgaatt cggtgattca acaagcagaa tcgttttgcg aaaggtatcc
     5221 agaatataaa ttatcttttc tttcagaaaa caagatgata aaagtcgagt tttcttctca
     5281 gtttttactg agtaaagttt attctatact tttagaggga acgattggtt atattttact
     5341 ggattcactt tacaaaggta cttatcaatc cttagaaaat cttagtcaaa aaattatata
     5401 agtttgcgta cgattcaaag aaaattaaga gaacttaata ctattttgaa aaactatcat
     5461 ttatcttgca gcttgaaaaa aggtaatccg atagaaggag aagaataccg tatccgatac
     5521 ttttttcact tgatgtattg gcagtcattc gacgaaaatc attctgatat attatcaagt
     5581 ataaaaaata aacgtcaact attagaaaaa tttgcgaaac atgcgccata tacgcgtagt
     5641 atagatagaa agaaatggat cagcctacta agaatttcgt tgcaacgaat gaaacaaggc
     5701 cactcgatta cgtatgtccc agaagagatg aacaaatttg tgcatccatt gataacaaaa
     5761 gaagagttta cgcattacat actagagcct ttttttgaag caaacttctg gtcgatgaat
     5821 cacatcactc caacagagca agcttacctt tattttatgt ttggtgtaat gaacacctat
     5881 ttggaagaag atttgttgga tactccagat aaagtacaag aaagttgggg ctggattgaa
     5941 tcgtctattg tagaaaattt tgaaaaaaac ttcaagattt gttttacaac ttcagaaaaa
     6001 aattatctat atgtcaattt ggcaatgatc catttgtatt caagggtttt tgggacaaaa
     6061 aagaaggtgg atgcttttgg aaaatcagca gaagacagag attttcagca tatatttcca
     6121 gtgatgtatc caatcatgca acagtttttt agtggggtag ctcgcagaat tccagagctt
     6181 aatacttatt atgaaaagaa cagacggttg atttttcaat actgtatgtt agtcagggat
     6241 atttttataa aacacgaaca acctgtcata ttctatattc aatcaaagta tggtaaaaca
     6301 caggaattat gggcaaagaa aaggatatta tctatgactg aacgcccaat aaaatatagt
     6361 gcatccgctg atcagttacc tgatattgtc attagcgatt atcctatcga caaaaaggca
     6421 tatgatcaaa cgaatacaca gatattttac tggaatggac aacctacaaa aaatgattgg
     6481 gcgcgtctga aagctgaaat cataaaaatc aggaatgaga aaaatagatc catattggaa
     6541 aaattggatt tcgttaatta agaaaagcag attgtttatg ccaaaattaa gacattgcaa
     6601 aaagattatt ttctttaaaa tcgacaagat gaccagaaag caagagttcg ttgagctctt
     6661 gctttctttt agttttagaa aggaacatcc tgattttatc ttcgctaaat ccagtcaaaa
     6721 gttttgcaga ttggtcgtag ataatcggtt ttttcaataa agaaggggat gtacgaatct
     6781 caatatatag ttcactcaaa ctgagttcat ctattctgtg aacaagattt ttataactaa
     6841 tagaatgagt agagagcatt tcggtcacgc cgttgtttgt caattttagt aagtggataa
     6901 attcattttt ggttagtggt tgacgaatta agttctgttc gataaacggt atatcatgga
     6961 cgataagcca acgttttgcg cgtcttgaag acgagcagcc agaacctgta tacaatttaa
     7021 tcatcataca ttcctccaat agctaagtat ttatgaaata ataacatgaa gaaatagtcg
     7081 aaaagtgcca tttagaggtg taaaataaga aaatgttgtc acgtataatg gaactagcta
     7141 gataagaaat actattaaat caagaaaaaa gaaagaaggc acaagtatgt caaacacagc
     7201 cgacgcaata gtagtgatcg atttacaaaa aggggtatgt tttgattctt cgccgataca
     7261 cgaattagaa acagtgacag cattagtgaa taaaagaatc aaaacatacg aaacgattgg
     7321 gaaaccagtt attttcgttc aacacgaaga tgctcaatta gtgccacaaa caaaaccatg
     7381 ggagctattg tcggaattat ctattcctga gcacagttat tttgtgagaa aaacccatgc
     7441 gaattcattt tataagacta atttgagtgt tttattaact gaattggact gtcattcgat
     7501 cgaattatgt ggggcacaag cagagtattg tatagatacg actgtgaagt ttgctcatgg
     7561 attaggatac cagcttatga tgtgtagagg agcaacgaca acttatgata atccttttat
     7621 gaaagcaaag gaaacaatcg ctttttacga gaaaatttgg gataaacgat ttctgacatt
     7681 tttggagcaa taagttgttt cttcgtttaa aaaaagcaga atggatactg gtttatccat
     7741 tctgctttat tacgtaaaat gagaaaataa tcctgttcta tttttatggg ataaaccatt
     7801 tattttttgt ataaaaaatg tttgcgttta catataattc tcctagaaac ataaaaagga
     7861 gtgaatagct tgagaacaaa acaagtatta aagggagcgt tggtcatctt atttgctgta
     7921 agtacaagcg tcccgcaatg gacagtatat ggagagagca tttcttccga atcggaatct
     7981 cgggaggtag aaaccacaga aactactgat gctggaaatg aaacgaaatc gagtacttca
     8041 caaacagaaa caaatactga aacaacggtt gagacatctg ttactagcac agatcaagaa
     8101 acgaccgcta ccacagataa ccaacaaaca gaagaagcaa cagctacaaa aatgtcaaac
     8161 gacgaatcct cttctgctaa agtaagtgac aaagagaatg ggacagaaaa tgatgatatc
     8221 ggtaaaggtg aaaatttcaa tggtaaagaa tatttgaatt acttcggtaa acagatgaca
     8281 gaaatactta atggaccaac agaagacatc aagtcaaaat taatagagtt attagtcact
     8341 gagcttgctg ttaatgatta tggtgtagat aaagagatta tcaaacatct gattgctact
     8401 tatctattgt acgatatcgc ttttgcaaaa aacagtgtgt tgatgtcgat gcttggaggt
     8461 acagatgatg ggacaacgcc tacagaaaac acaggcttct atccaaatac aaaacaactt
     8521 catcaaactg tactaaacaa acaagatggc aaaatgatgg atgtatatgc atattatgtc
     8581 gatcaaggtt cagataaaac agtcatgatc catggcggat ttcgagggaa ttggaataac
     8641 gggatcgtta cagaagaata caatgatttt tataaggccg ggtataattt attatttgtt
     8701 gattccagag cgactggtaa tagcggaggc gattatgtga cctatggaca atatgagtca
     8761 gatgacgtcc tttactggat aaatcaagaa gttcgagagc ggccatctca aaagatttta
     8821 ctttatggtg gttcgatggg agcagctacg atgatgtctg tattagcgaa agatattcct
     8881 gtcaatgtca aaggaattat tgaaaattgc ggatttgcat caattgatga acaactacgt
     8941 tttacgtaca gccagacagt agcccccgca ctaccggatg ccataaaaaa tcagttagac
     9001 atcattgggg atcaagagca tgaagattta tttatgggcc ttttgaaaca atactatttt
     9061 gatcaggaga tgcatttgga tacaaaagct gctctaccta cgattggaat gtcagattca
     9121 ttgcctaaat tgattatcca tggaacagca gatgatgtag tacctgtgtc taacgcgcaa
     9181 aaattatatg agttatcagg agggtataaa gatcttttat tagtagaagg agcagggcat
     9241 ggaaaggcac aggaagttga ccatgctgcc tacacgaaac atgtaacgga ctttttgaaa
     9301 gtagtgttcc atgatcagat aaacgtaaag tatgtggatg aaaacaataa aagtctactc
     9361 aaagaccagg acgaaatcca gctttacgga gcttatggag aaaattatat gacagagcaa
     9421 aagacattcg aaggatacga attagcaaat gttgaaggac cgactgaagg gatttttaat
     9481 gagacgatac caactattat tttctattac aaaaaaatcc cagtagctcc accaaaaaag
     9541 caagatccga cagagaatgc agacaataag ggaaagaatg aacctcgaga ggatcaatca
     9601 agtgatgata cgcaaccgat tcagatgaca gtgaaagtac aaaaaaagac agatgcaaaa
     9661 aaaagaatgt tgccgaaaac tggagaaaag aaacattcgc ttctcattta ttcaggtgga
     9721 tttttatctg ttagcacgat tatcacatgg atttggcgaa gaaagagagg gtaaatgaat
     9781 gaaatggttc aagcgaatag tgattgcagt accagttatc atcgtagtta ttttagtcac
     9841 tgtatttttg attaatcaaa tcacaccaaa gccgattagc ttgcttgtta gaaaacaatt
     9901 tgacacaagt gaaaaagaac aagtatatgc ccgaccagat gatttccagc aaaaaatcga
     9961 acaaatcgat ataaaaaaag aaatatccta tccttcaaag tacaaaaata ataatatgga
    10021 tatctacaca ccgaaagtgg aaaagaaaaa attaccgatt cttttctgga tgcatggagg
    10081 cgcatatgta ggaggggata aaaatgattg tcgtgattat ttggaatatc tatgttcaga
    10141 cacgcagcaa atcatcgtaa atatagatta tgaacgatca ccggaagcaa aacatcctac
    10201 accagttatc caattgaacg aagccattca agcagctaaa aaagagataa aagatcaagc
    10261 agattggtcg aatatttcga ttggtggaaa ttcggcaggt gcacaaatta gtggagaata
    10321 tttgttagca cttcaaaatg aagaaattaa aaaagctgat catcttgatc cgactttgga
    10381 gaacaagcag attacgaagt ttatttcttt gtctggtctg ttggatcctt ctgcacttac
    10441 tcaagtaagt gataaaatct ctagctttct ttatgaaaaa tgtggatggg cttactttga
    10501 taataaggac tttgaacaat cagagaaggt caaaagttta gccttggtca gacatgcgga
    10561 tcgttggacg caaaacacat tcttaacgga tggaaataca aatacgttta cgaaacaaat
    10621 ggaagaagta acttctgtat ttgagaaagc gggggtgaaa gtcacaaaag tagattatgc
    10681 ggagaaaaat gctgttttga accatgaata tcagtttgat ttcagcaata aacaagcgca
    10741 agaaacatat caaaagttag taatgttttt caaggagtaa agtcttatga tgcaaaagag
    10801 gttgtaatct gtcacttagc tccaagtcac aaggagcaat ttcaataaac aagcttttca
    10861 tggtttatga atattgtaac ttgtgactga ggagttagag atggcaaggg gcacctttta
    10921 ttcgaaattt gggaatatca cacgattatt gtcacgatct cttttacgta aattttataa
    10981 gtcagatttg ttgttttgat cgtttaaaaa aagcaacaaa tccgaagcct gcggaggcaa
    11041 gaagggacaa aaagccgagt ggtaagcaaa agaatgctgg ttccactaat attccgttgt
    11101 tattgatata aggctgggaa caaagatgaa tagcaaataa aatcaatgca ctagcgaaaa
    11161 aaagcaaaga aatatggata gctttcataa gcagcacctc cttttttata attgtatgat
    11221 aaatagatta agaatctata aatgtgacaa gtttgttagg atgtgaataa aatgatcatc
    11281 tagcgaactt gaaacaaaga tggctaatga taagcaatta atgattcagc aatcagatag
    11341 gtacaaagtt taccatcata cgtctagacc aataatagaa aatatgggaa tataatagaa
    11401 aagatttagg atacccccaa aagaatttcc ccaaaaattc gatgtatcct aaactttttt
    11461 attttacata acaatcatat caactgtgaa ataaaattac aaatgataac ctaaaatgag
    11521 gccaaaagcc agtgttatca aggaaatact taattcacca aaattttttt taatttttta
    11581 gaaaataaga aacaaaaata ataaaaaaaa gaaaagataa attttttact actgtatact
    11641 aactttgtta tcgcatctaa caagtaactc gaataatacc aatacaacct tctccaaaga
    11701 tgcgatgaca tacgttctaa cccaccgact attgatgttc tgtaccaccc ttgcagaacc
    11761 aaaaaagcca ctaccaaata tttggtagtg gctttttttg ttttatggat ttttcgcttt
    11821 ttctgttatg gtgctattct ttgatttcag aaatagtatg tcgaacttta gcgatagaac
    11881 gacgtgattc tttttcgttg taaaacatca aaatcacata tagagagtcc aaaatgctta
    11941 gttgagaaat acgggaagct aaagcttcag atcggaattc tgtttcttca gaaatagaaa
    12001 taaaaacgac atcgccaagt ttagcaaggg aagaattagc ttggctagta ataacgattg
    12061 tttttgctcc agtttttctt acggtttcag caatatggat tgtttctttt gattgccctg
    12121 tgtgagaaat caaaacagca cagtcttttt ccgtcaataa agaagcttcc atcaattgaa
    12181 tatggtaatc cgtgctgtga gaagttgcga taggggaacg caaaaattta tgataagcgt
    12241 cagttgctac aatctctgaa ccgccaacac cgaaaaaata gacacgttta gattcattga
    12301 taatagtagc cgcttttttt agatcctttt gttgtaacaa cttttttgtg tcatttaaag
    12361 ttgaaatact agactcgaac accttttgcg ccatagtgag ctcagtatct gttttctgaa
    12421 tattttcgtg gatagaaata gcagatagat cattttcttg gatcaacatg gccattttaa
    12481 aatctttaaa tccattataa ccaagttttt ttgtaaattg aaaaaaagta gagtcagcaa
    12541 tgcccagttc acttgctaaa ttgctaatag gactatgact tactttgctt ggattttcta
    12601 aaatataatc ggcgatagcc tgttcttttg ggctgaagtc gttgtacatt gttttgattt
    12661 gtagtcttat ggagacgctc atgagaattc ctcattttca taataagatt atcatttttt
    12721 ccgttctcat taatgttaaa gatacaagga gagtaggaaa aaatcaaaca aaaaatattt
    12781 ttgtaaaatc tatttacaaa aaaatttttt tgtataatga gggtataaga aatggaggcg
    12841 ctatcatgga aattggtgta attggtttgg gaaaaatggg attgaattta gctttaaact
    12901 taaaagagca ccatcacaaa gtacaaggac tcgacatttc aagtacagct gttagtcagg
    12961 caagagaaaa tgacattcct gcttatcaag agatctctga atttctagct acttttgagc
    13021 agaaaaaaat catctggtta atgcttcctg ctggagagat aaccgaaaac atgttaagaa
    13081 aactttttcc aaaactcgga ccaggagaca ttattattga aggcggaaac tcttattata
    13141 aagattcaat ccgtcgagca gaagagtttc agaaaaatga aatcggttac ttggattgtg
    13201 ggacttctgg aggaatcgaa ggagcacgac atcaagcctg cttaatgatt ggaggagata
    13261 aagaaacttt tctatccgtg gaacaattat tcaaagatgt agcaattgaa agaggatatc
    13321 tgtatgctgg tgcatccgga agcggacact tcttgaaaat gatccataat ggaatcgaat
    13381 atggaatgat gcaagcaatc ggtgaaggat tccaacttgt acaaaaaagt gagtatgctt
    13441 ttgacttgga acaagtcgca cgtgtttgga atcatggttc ggtgattcgc ggctggctga
    13501 tggaaatcat ggaagatcag ttaaacgaac atcccaattt aagtaattat cggggaatcg
    13561 tttctgcatc aggtgaagca aaatggacgg ttgaaacagc gctagaaatg gctgttccag
    13621 ttccagtaat tgcaactagt ttgttcatga ggaatctttc acaggaagaa gatagttttt
    13681 cagcaaaagt agtttcagca ctaagaaatg ggtttggcgg acatgaaata gttgaaaagg
    13741 gtgagtaaaa tgccagatta tcatatagca atcgttaatt ccagcagttt cggaagagtc
    13801 tttccacacc acttggaaag attaaagtca gttggagacg ttcatttctt tactgttgat
    13861 caagagattc caggaaaaga actagcggag ttacttaaag gattcaatat cattattgca
    13921 agtgttacgc cattttttcg acgagatttt tttgaaaaca aagatgaact gctattgatt
    13981 tcccgacatg gtattggtta caacaatatt gatttaaaag cagcaaaaga acaccagaca
    14041 atcgtatcta tcatacctgc tttagttgaa cgaaatgctg tagcagaaaa taatataact
    14101 aatttgttgt ccatgcttcg acgcacgaca caagcacaag caagagtcaa ggacgatcga
    14161 tgggaagatc gggcggagtt cgtcggtagg acgctgttta acaaaacagt tggtgtgatt
    14221 ggtgcaggaa ataccggaag cggagtaatc gaaattttgc gtaacggttt tcgctgtgat
    14281 gttctagctt atgatcctta caaatcagat ttatacatcg aaagctttgg tgcaaaaaaa
    14341 gtagaacttc aagaattact ggaacaatca gatatcattt gtttatgtgc gaatttgaca
    14401 gaagagaact atcacatgat ttctgataaa gaagtcgatc agatgaaaga aaatgtttat
    14461 ctatctaata gtgcaagagg cgctctagtt gatgaagaag cgatgattaa tggtctgaaa
    14521 agcggaaaga tcgcaggata tgccacagat gttttagaag aagaaccggg acgtcaagat
    14581 catccgtatt tagcgtttga acaagtagtg attacgccac atatatcggc ctacacaagg
    14641 gaatgtttag aagcaatggg tgaaaaatgt gtcagagatg tcgaacagat cagtcagcac
    14701 cttcttcctg aacgttctgt ccagacaaag agcaactata taaaaggatg atgaagaaaa
    14761 tggtgaacgg tttaaaagtg aaaacaggcc ctcaatttta tttatatgaa gaaggtggta
    14821 tttcaaaagt ttctgatctc ttgaaatcat acggcgcgaa aagagtactg gtcacccacg
    14881 gaacggtatc atgggaaaag gcgctaccta aattagtatt tttgaatgac gaaacgattc
    14941 aattttttta tcatcgttat tctggagaat gtagttatgc tgaagccaga cgaatagcta
    15001 caatcatcaa aaaaatgaaa tcgatttcgt agttggcgtt ggcggaggaa aactgaccga
    15061 tctagtgggt tatagtgcca atcttgcaag aatcgatttc ggagtcatcc ctactttagc
    15121 tagtaattgt gctccatgga cacctcttgc tgtcatgtat aaggagaatg gacaagcaga
    15181 agggaaaaca gaacactttt acagacaagc tgcttttttt ataacagatc cccaattagt
    15241 gattgattcc cctgttccat atttcattgc cgggttagca gatacactag caaaatggta
    15301 tgaatctgag ctcatcttag aacaagattt tttgcaagat gaatcatttt tgaagctagc
    15361 acaagatact gcgaagatct gcaaagaaga gattttgaat cattctgcta aagcaatcca
    15421 agatatggca caaagaaaac tgacatcgga gttcaaacag ctttcagaga ttatctttgc
    15481 tgttgctggt ttagttggag gattaggaga taaatacgca agaaatgtgg cagcacatgc
    15541 tatgcatgac gctatcagta aatatattcc ggaaagccat cgttttctac atggagaaaa
    15601 agtagcgtat gggattttct atcaactggc actagaaggt cgctgggaaa aaatagacga
    15661 gttatatcct ttgtatcggg aattagaact gccggtttct ctagaacaaa tgggattatt
    15721 tccgaaagat aaacagataa tagataaaat ggctgaattt attgattcga aagagaaagt
    15781 gcatttgatt cctatagagg taacacagaa atcactgata cagtcaatga tggaactgga
    15841 aggttatatc agaaagatct gaaggaggag gacacatgga aacattaagt gtagtacaaa
    15901 gtttgttgat tgctttatgg gtagccgcgg ttatgtcccg ctggttaggt ggaggagcca
    15961 cgttgacctt acgtttttct cctttgatga ctggattagt cgtcgggttg atcatggggg
    16021 aagttgcaca agcgatgatt gttacagccg ctttgcaaat gatttatatg ggggtttttt
    16081 ctccaggagg atcaatgcca gctgaaccat ctattgcagc agctatcgca gtaccagtcg
    16141 cattattagg ggatctgtcg ccagaagcag cgattgccgt tgcggtgcca gtcggattgc
    16201 tcggaagtta cttgtatcag tttcgttttt tcatcaatac ttttttaggt aaatatacag
    16261 acaaagctgt agaagatttg aatacaaaag ctatggcccg atcaattatt ctttatccaa
    16321 cggttgcctc atttttatta ttcgttccgc ttgttttcat tgctttatat ttaggggcgc
    16381 cattgatcgc tgatgtaatc aaagctttag agggaacagt cgttatccac attcttgaag
    16441 tagtaggtgg agggttagcg gcaatcggta tcgcgacaac tgtatacgtt atcggtcgaa
    16501 aagattatct ggtctttttc ttccttgctt attttatgag tgttgttttg aaatctttag
    16561 atattacgat ggttacttat gccatttttg ggattattat cgctttgatc tttgtccagt
    16621 cgcaaaaagg gaaacaagta cagcctgcca caagcaataa caattcagca tcttttgatg
    16681 acgaagatga ctatgatgac ggattttaat ttaggaggaa tgggaaatgg ctgaaataat
    16741 ggataatcaa acaggtgctc ctgaagaaat cacgaaaaaa gatgtaacaa aagcctatct
    16801 gagatggcat tttgcaaacg aaattcctca ctcttttgaa cgttacttgg cgccatcact
    16861 actatacgga atgatgccaa tcttgaaaaa actttataaa gatgaagact ctttaaaagc
    16921 agcatataaa cggcagttac tgttcttcaa cactcaatta agctggggtg gcggtgtgat
    16981 tactggccta atgtcttcta tggaacagca aagagcagaa gaagagtatg aagaaaaaga
    17041 gatcttgatg caggatgact tgatgtataa cacgaaagcg ggattgatgg gggcactagc
    17101 aggaatcgga gatgcaatcg attcaggaac cgtccaatat atttttatcg caatcgcggt
    17161 accttgggca caacagggaa gtcctttagg cgcacttttt ccttttatct gctttgggtt
    17221 gtatcaggtt ttactagggg tatttttcgc aagacaagct ttcactatgg gccgtaatgc
    17281 tacaggccta aagcaaaaca ctggtgttca gacagcgatt gaaatgctat cagttttagg
    17341 gttgtttatg atgggggtgc ttgcgggaaa ctatgtaaaa gtagaatctt cattgaaatt
    17401 tgcgatatcc ggacgtgagt ttgttatcca ggaaattctt gatcaaatcg tgccagggat
    17461 attaccttta gctgtcgtaa tgggtgtgta cttgttctat acgaaaaaag gattgaaagt
    17521 cacacaagca ttattatggc tgactggaat attaattgtg ctagcaggaa tcggtatttt
    17581 ataaaaagaa gggaacgtga ataagatggg tgtagtcaat ttagcgcgtg tggatgagcg
    17641 tttgatccat gggcaagtaa tggtaacgtt atctcaaaaa agtggagtga attccatttt
    17701 tgttgtagac gaagttgtag caaaagataa atttatgaga gatctttaca aaaatgcagg
    17761 aagccgtaca ggacaaaaaa caattgtcat tacaccagag aaagctaaat tctattggga
    17821 tgaatatcaa tttaaagaat acaattgtat tttgatcgca aaaacagtcc aaacgattta
    17881 cgacttagta aaacacggaa tccccatgga agaattgaat attggaggga ttgctcaaaa
    17941 aaatcctgat acagatcttt tagtgacgaa atctgtttat ttaaataaat cagatgctga
    18001 aaaattgaaa gaaatgaatg aacaatatgg cgtaaagaat atttattttc aagccactcc
    18061 atctgcacct aaaacaggat taaaagatgt attgaacaag tttgatttgt cataaacaaa
    18121 tgcttagaaa aaagataaag agggcgaaaa aatgaagaag aacgagctgt ttcgtgattg
    18181 ggaatttcgt tatcgctata tttaccgtaa gcgccgtaca aaaaagagta aacagcgttt
    18241 tctttcagca ttagtatcag atatttacag tatgagaaca gatgtgacag tcattgctta
    18301 cgatacgcta gcctaccgat caaaaaatat ttatgttgga gatatcgaaa aagcagagaa
    18361 agttatctgt acttattacg atacacccgt tcatgcatta ggaagttatt tcatgtttga
    18421 ttggaaagac caaaggaaaa aaacaatcta ctctatatta ttgtccttca ttttgttgtt
    18481 cagtttaggt tggtggggaa tgatgatata taacaaaaat cctcatcacg tattcgatct
    18541 gctatccgta taaacaggta tcactgtact agcatttggg agctactttt tcttattggg
    18601 aaaagcagct cgcggatggc ctagcagaca aacttttatt cgaaatactt catccatatt
    18661 aacgatgcta gaaatgatcc gtacgattga tgatccgagt gtagcgtatg cgtttgttga
    18721 tgaaggctgt tatggagaaa agggcttaga cagcgtgaga tcgggtatga aaaaagaggc
    18781 tattcttttt tatctagact ctgttggggc agatacaccg ctacagtttt cgggaaatta
    18841 tttttcaaat aaagaacagt ggctgaaaca agttgataag ttgaaagaaa aaaacgtcaa
    18901 ttatattttt agtgcaagaa aaaagcaagc gcagttcttc tatttgacca aaacagattt
    18961 acgagggaaa acatttaatt ggcaaaatgc caatcagatt attgctcttt ttcgataagt
    19021 aaaaagtgca aaacaaggag tgagaagact aatgttggaa atcatgatcg ttacacatgg
    19081 taagttgagc gaaggactga aagatgcggc ggaagtaatt gtcgggacat cgagccatat
    19141 tgaaacaatg tgcttagagt ctggggagga catccaaaca ttcggagaga aggtcaaaga
    19201 aaaattaact atgatcaaca cagcagaacc catgctagta tttgttgatc taattagcgc
    19261 aagtccgtac aatcaagcgc tcttggcagt caatgaactg actgaagaaa agaaagcagc
    19321 cacttatgtc atagggggcg tgaatctgcc aatgttgtta gaagcaatca atcatcagat
    19381 gcttcacaca ccgatagaag aagcggtgga acaaattgtc aaacaaggaa aagataattt
    19441 aactgtttgg catgcttcag cggaagaaaa aaaattagat gaggacgatt tttagaagga
    19501 aggctgaaaa gatgaagtgg ggatttagat ggtatggtga aaaaggggat tcgatcccat
    19561 taaaatatgt tcgccaaata ccgggaataa atgggataat tggaactttg ctgactaaaa
    19621 tgcctggaga tgtttgggag atttcagaaa ttgaggagtt gaaagcatct gttgagagcc
    19681 aaggactgga actgcttgga attgaaagtg tagcgatcca cgatgcaatc aaggcaggga
    19741 cagatgaacg agattactat attgataact atatacgaac aatcaaaaac ttgtctcgat
    19801 gtggggttcg attgatttgt tatagcttca aaccaatttt tggatgggcg aaaactgatt
    19861 tgtttaatga aaacaacgat ggaagctatt ctcttttata cgatcagaaa atcgtcgatc
    19921 agatggagcc aggagaaatg tatcaattga tacacagcca gtcaaaggga ttcaaattgc
    19981 cgggttggga agaagaacgg ttgaaaaaat tcgctcagct ggaaaaactg tatgaaggaa
    20041 tgaccgaaga agaattattt gaaaatctga cttatttttt agaaaaagtg attccagtgt
    20101 gcgaaaaagc agatgtaaaa atggctatcc atccagatga tccgccatgg gaactttttg
    20161 gttttcctag agtgacgaaa aatcttggcg acttgaagaa aattctaaat gcagtagatt
    20221 ctccatataa tggactaacg ctgtgcacag gatctttagg ggcaaatccg gaaaacgatt
    20281 tagttgaaat catccatgag gtaggttcgc gcatccattt tgtccacttc agaaacgtgg
    20341 agtttttagg agaaagaaag ttcaaagaaa cggcacatcc ctctacagaa ggctcccttg
    20401 atatgtatca tattatgaaa gcgttggtgc aagaagggtt cgacggtcct atacgccctg
    20461 atcatggtag aaccgtgtgg ggtgaagtgg ctatgcctgg atatggcctg tatgatcgtg
    20521 caatgggact cacttacatg caaggtctat atgaggcgat aagtaaggaa aaaccactgg
    20581 gagagcatta tgaataaaat caagctcttc atctttgata tggatggcct tttattagaa
    20641 actggacgtt tagcttatcg tgcttatgta aaatcagcac aaaagtatga ttatgaaatg
    20701 cgtaaggaag tctattattt actaactggc caaacagaaa tggcgataag agaacaaatg
    20761 ggcattttgt acggagaaga tgttccatat atcaaatggc gagaagcaat caatcaatat
    20821 aaagaaaaaa tcgtgaaaga agataagaga gtatatacga aaaaaggagc agaagaaatt
    20881 ttatcttttg caaaagaaag aggaatccat acaatcgtgg cttcgtctaa tacacgggta
    20941 aaagtagaaa tgtatttaaa aatggaaaat ctatatgcct tgtttgatca aatcatttca
    21001 ggggatgatg taaaaaaagg aaagccggaa ccagagatct ttttgaaagc ttgttcaaaa
    21061 atgaatattc ctccaagtga agcacttgta tttgaagact cgattgcagg gatcgaagca
    21121 gcaaggcgag cgggcatttt gtcttttctc atcaaagatc atttgatagg gttgcccgat
    21181 cataatggga agcataagtt gaaagtagat gtaagtttat atgaatccaa taaagcagac
    21241 tatgaatttt atgacctgca tcaagcaaaa cgatttttag aaagtaaagg gttgtatctc
    21301 taataaagag gactattttc tagtcctctt tatttattgt cctgcacgac tgagggaaca
    21361 gatgaaaaag aagtaatttt ttattttgaa gtatctacct tatttgtagt gaacaattta
    21421 gaacaaacac aaaacgcatc tactgttatc taccagtaga tgcgtttaaa gagaagaacg
    21481 agaatcgtcc atatgagggt ttc
//
LOCUS       DARPZJ010000042        20663 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.044, whole genome shotgun sequence.
ACCESSION   DARPZJ010000042 DARPZJ010000000
VERSION     DARPZJ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.044"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            168..362
                     /locus_tag="SLE23_001929"
     CDS             168..362
                     /locus_tag="SLE23_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468830.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..929
                     /locus_tag="SLE23_001930"
                     /pseudo
     CDS             631..929
                     /locus_tag="SLE23_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1026..1460)
                     /locus_tag="SLE23_001931"
     CDS             complement(1026..1460)
                     /locus_tag="SLE23_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8468831.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1692..2402)
                     /locus_tag="SLE23_001932"
     CDS             complement(1692..2402)
                     /locus_tag="SLE23_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEI8468832.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2392..3252)
                     /locus_tag="SLE23_001933"
     CDS             complement(2392..3252)
                     /locus_tag="SLE23_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEI8468833.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3257..3895)
                     /locus_tag="SLE23_001934"
     CDS             complement(3257..3895)
                     /locus_tag="SLE23_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEI8468834.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3910..4209)
                     /locus_tag="SLE23_001935"
     CDS             complement(3910..4209)
                     /locus_tag="SLE23_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8468835.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4252..5736)
                     /locus_tag="SLE23_001936"
     CDS             complement(4252..5736)
                     /locus_tag="SLE23_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEI8468836.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5756..6217)
                     /locus_tag="SLE23_001937"
     CDS             complement(5756..6217)
                     /locus_tag="SLE23_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8468837.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="SLE23_001938"
     CDS             complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="SLE23_001938"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEI8468838.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7520..8290
                     /locus_tag="SLE23_001939"
     CDS             7520..8290
                     /locus_tag="SLE23_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEI8468839.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8563..9390)
                     /locus_tag="SLE23_001940"
     CDS             complement(8563..9390)
                     /locus_tag="SLE23_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8468840.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9958..11193
                     /locus_tag="SLE23_001941"
     CDS             9958..11193
                     /locus_tag="SLE23_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEI8468841.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12192..12452)
                     /locus_tag="SLE23_001942"
     CDS             complement(12192..12452)
                     /locus_tag="SLE23_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEI8468842.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12479..13780)
                     /locus_tag="SLE23_001943"
     CDS             complement(12479..13780)
                     /locus_tag="SLE23_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8468843.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFAVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14072..14530)
                     /locus_tag="SLE23_001944"
     CDS             complement(14072..14530)
                     /locus_tag="SLE23_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8468844.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14543..15874)
                     /locus_tag="SLE23_001945"
     CDS             complement(14543..15874)
                     /locus_tag="SLE23_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HEI8468845.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGRDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15885..17327)
                     /locus_tag="SLE23_001946"
     CDS             complement(15885..17327)
                     /locus_tag="SLE23_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8468846.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17314..18078)
                     /locus_tag="SLE23_001947"
     CDS             complement(17314..18078)
                     /locus_tag="SLE23_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HEI8468847.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18182..19057)
                     /locus_tag="SLE23_001948"
     CDS             complement(18182..19057)
                     /locus_tag="SLE23_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8468848.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19312..19396)
                     /locus_tag="SLE23_001949"
     tRNA            complement(19312..19396)
                     /locus_tag="SLE23_001949"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19360..19362),aa:Leu,seq:caa)
     gene            complement(19414..19485)
                     /locus_tag="SLE23_001950"
     tRNA            complement(19414..19485)
                     /locus_tag="SLE23_001950"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19451..19453),aa:Gln,seq:ttg)
     gene            complement(19495..19567)
                     /locus_tag="SLE23_001951"
     tRNA            complement(19495..19567)
                     /locus_tag="SLE23_001951"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19532..19534),aa:His,seq:gtg)
     gene            complement(19629..19713)
                     /locus_tag="SLE23_001952"
     tRNA            complement(19629..19713)
                     /locus_tag="SLE23_001952"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19677..19679),aa:Leu,seq:caa)
     gene            complement(19734..19804)
                     /locus_tag="SLE23_001953"
     tRNA            complement(19734..19804)
                     /locus_tag="SLE23_001953"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19770..19772),aa:Cys,seq:gca)
     gene            complement(19850..19921)
                     /locus_tag="SLE23_001954"
     tRNA            complement(19850..19921)
                     /locus_tag="SLE23_001954"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19887..19889),aa:Gln,seq:ttg)
     gene            complement(19933..20005)
                     /locus_tag="SLE23_001955"
     tRNA            complement(19933..20005)
                     /locus_tag="SLE23_001955"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19970..19972),aa:His,seq:gtg)
     gene            complement(20008..20081)
                     /locus_tag="SLE23_001956"
     tRNA            complement(20008..20081)
                     /locus_tag="SLE23_001956"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20047..20049),aa:Trp,seq:cca)
     gene            complement(20088..20168)
                     /locus_tag="SLE23_001957"
     tRNA            complement(20088..20168)
                     /locus_tag="SLE23_001957"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20132..20134),aa:Tyr,seq:gta)
     gene            complement(20170..20245)
                     /locus_tag="SLE23_001958"
     tRNA            complement(20170..20245)
                     /locus_tag="SLE23_001958"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20210..20212),aa:Phe,seq:gaa)
     gene            complement(20281..20353)
                     /locus_tag="SLE23_001959"
     tRNA            complement(20281..20353)
                     /locus_tag="SLE23_001959"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20318..20320),aa:Asp,seq:gtc)
     gene            complement(20363..20435)
                     /locus_tag="SLE23_001960"
     tRNA            complement(20363..20435)
                     /locus_tag="SLE23_001960"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20400..20402),aa:Val,seq:tac)
     gene            complement(20451..20522)
                     /locus_tag="SLE23_001961"
     tRNA            complement(20451..20522)
                     /locus_tag="SLE23_001961"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20487..20489),aa:Glu,seq:ttc)
     gene            complement(20537..20626)
                     /locus_tag="SLE23_001962"
     tRNA            complement(20537..20626)
                     /locus_tag="SLE23_001962"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20590..20592),aa:Ser,seq:gga)
BASE COUNT         6529 a         4320 c         3276 g         6538 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa tcatgtgttc attttttata ttagttcgaa tttgcaaaaa attgtatttg
      901 ataaagaggt gagtaaaaaa ataaaatagc tgagcattgg aggatagatt gagtgatact
      961 aagtctatcc tcttgttttt ctaaagaact aagctagaat tttttctttt gtacgttatt
     1021 atatgttatt tgtcattacc aaaaagcacc ttttttcttc tagtatctat gacataagaa
     1081 ataccaccca tttcctttac ttgaacaaat cctactgatt cataaaattt ttttgttttc
     1141 tcagtatcat ctgtcaataa ttcgatttgg actggtccat aactagtgat cttctccaaa
     1201 gcttcattca aaagcacttt gcctattcct tggcgctgat acctcggatg aatgaggata
     1261 tcttgaataa atgcgatcgt cgcaaaatca gtgatccaac gaacgattcc gataatcttc
     1321 ccttccccat tacgctttat cagagattca gattgttcaa atgctctagc taaccttgca
     1381 gtgtcttttg tgtaattcgt ccaaccaacg ctcttatata attcagaaat ctcatcgatc
     1441 ataagggaat caatattcat ttttttcttc ctttcttata caattctccc tctaataata
     1501 cagttctttg actatttaat ctatcacata taactctcct gtaaagattc tctcgattcc
     1561 ttaaaattcc tctttccttt tagaatgcat actttttgat aaataaaaag gttgtgataa
     1621 attttcttca caacctctgt ttctctctat caagtgttat cttttaattt tctaccctta
     1681 ccctagcatc tctattgccc gtagtatgca tactttccat gtttgcgaaa ataatgttta
     1741 tctagtaaat attgcgggat ttcacatata ttggggttga tcagctcgtt ttctttggcc
     1801 atcagacaaa tttcatctaa gatcaaactg ttttctactg ctttcatagg tgaatccccc
     1861 catgtgaacg gtccatgtcc atagacaagt actccaggga cttcgtttgg atctaatttt
     1921 ctttccttaa acgtctcgac aatcacattc cctgtatgaa cttcgtaagc ttctcttact
     1981 tcttctttcg ttaattggcg tgtacaagga accttaccat aaaaagcatc agcatgagtc
     2041 gtgccataag ctggcaaatc gcgtcctgct tgcgcccaca tgacggagtg cgtggaatga
     2101 gtatgagtaa tagcagttat atcttcaaaa gtttgataca aaacaacatg tgtggggaga
     2161 tctgaagatg gttttaagct atcttcttct attatatttc ccgacaaatc tgttaccacc
     2221 atttgatctg cttgcatgca ttcatatctg acaccgcttg gcttaatgac gatgactcct
     2281 agctcacggt ccacttcact cacattgccc caagtcaatt tgactaatcc gtatcgcggc
     2341 aatgccagat ttgcttcaag gacacgttgc ttcattgctg caattttttc ttcacaagac
     2401 atcatagcca gcctccttca atttagaact taagtagtct tttgcctgct ggatttctct
     2461 tcgaaagtct tggctttttt cactccacat ttcaatcaga aatgttccat cataatctag
     2521 acgtttcaaa tgtcttaata atccaagaaa atcaacacaa ccgctaccaa aaggaacatc
     2581 acgaaactgg cctgaatatt cttttgttac agggtaagta tcttttaagt ggatagcagt
     2641 gatataatcg atccctttct caagttctcg agccggatta ttttccggcc atgcggacaa
     2701 attgcctagg tctggatata cttgtagaaa aggtgaatga atctgttctt tgatttctaa
     2761 aaattttgaa atggagttca taaatggatc atccatgatt tccacggaaa gaatgatgcc
     2821 atatttagaa gcttccttta cgctttcttt tattccttcg ataaagtctt ctctggaatt
     2881 cattgatttc tcttcataat aaacatcgta tccagctatt tggattactt tgacgcttag
     2941 attatgcgcc aaatggattg cttttttcat tagttgtttc gctgcttttt tcttttctgg
     3001 atcagcagaa ccaaacggaa atcgccgatg cgcacttaaa caaatcgaat ggatacgtac
     3061 accggagctg aacatctctt ctctcagctc agctatcttt tcttcagacc aatctaatcg
     3121 tgctaaccgc tcatccgtct catcaatcga catctcgata aaatcgaagt ccatttcttt
     3181 tacaagggaa aaacgttctt tccatgaaat atctttgggt aacgcttttt cataaatccc
     3241 aatttgagcc atttccttac ccccagatac gaatgatctc atctttgaag ttttgtgcgg
     3301 ccttcatcgg atcatttgct gctgtaatac cacgaccagt gataaaggta tacacatcga
     3361 tcccttcaaa taagtgtaat gtgtgtggat ttaatccacc agttacagaa acattaaagc
     3421 ctagttcaat cagttttttg atcttcgata aatctttttc accccaagtt tcaccagata
     3481 acagcgcatc acggctttga tggtagatta cctgccggat accgatgtta tgccaatcca
     3541 tggcttgttc aaaagtccaa ttgccgtaga gttctacttg caattcacct atttcttttt
     3601 gtgctgcctc catagttgga atcgttgcac aacaaatgac tgtcatccag tctgctcctg
     3661 cttttgcaac attactcgcc actgttcctc cagcgtctgc acatttcgta tcagcgacta
     3721 gttttttatc tgggaacata ctgcgaatac agcgaatcgc tttttgtcct tcctgtaagc
     3781 aaagaattgt gcccacttca ataatatcta ctacatcacc aactttcata acatctccta
     3841 atgcatgttc taagtcattg tgatctaacg caatttgcaa attcggcctg ctcatcttag
     3901 ttccttcctt tacttgtttt tttggtacca ctttgtttca gcaaattttt cactgatttc
     3961 tttgactgac atcacatttt tgataccgat aactgtaact ccttttttct ctgcctgagt
     4021 aaacatattc aaaaaattga ctggcgtaaa aactacatcg tattggccag ctgaactttt
     4081 tccctctgaa atggcacaat gatggatttt ggtaattggt acgtttagtt ctttcattgc
     4141 tttttccaca cttctcatca tcatcaagct tgttcctgat ccatttgcac acgatactaa
     4201 aattctcatc ttaatccctc cattatgagt gttgtctaat cagattttct tttatactct
     4261 ctgcttttct gcatatgtgt catagtcttc tacaatcaaa aaataaccat caggattttt
     4321 ccgatattgt aactgcggaa tagccaataa accaatgaca actacggcaa ttccagcata
     4381 acctaggact ttcatgatta ctgtaaacaa tggccaagct gttgcccagt cgaacatccc
     4441 gatataacca ccgtatgttg acatcccaat ccatgtagcg aataatgctg aaccgcctac
     4501 ttgtatgatt cctgaaagaa acgggaacag gcaagcggct ttgaatccac ctcggttatt
     4561 ggcataaact gctataacgg cattatcaaa gaacaacgga atgaaaccgg ctatgacgat
     4621 cgttggtgat ttcaataaaa tcagtaaacc aatcatcaaa aactgtccca aagcaccaaa
     4681 caagaaccca atcgttaccg catttggcga accaaagcca aaagtagcag ctacgtcaat
     4741 tcctggaaca gctcctggta aaatcgtgtt tgagattcct tggaaagatt gagttagttc
     4801 atcgacgaat gtccgaacac ctaattgcaa gatcgccaga tataccgcaa aatttaaaga
     4861 agtcgtcata atgtagaata agaaactctg cccttcttgc atgaattgcg cttgaatcaa
     4921 ataatctttg cctagtacaa tcagaatgat cccaaagaaa aatagcatga gtaacgaagt
     4981 agcaaccata ttctcattga aaatcgacaa gaatcctggt aatttgatat cttcaatttt
     5041 tttgtcttgc ttgattgatc tatttttctt ttcatcccgc tttttcatcc actcagctaa
     5101 ttttgcaaat ataaagattc cgaacatttg ctgatgtgcc actgcaaatc cggcaccttc
     5161 tgtcaattcc tgcgtgattc ctactgttaa gttagaagct actgtccaat aacaacctaa
     5221 aatcagtccc ataaaaatca atgcttgtat cctacctaga tcaggaaagc aaaacagtaa
     5281 aatccaaaaa gcggtagctg cttgttgaac ctgaacgttt ccggtagtga aaacggaacg
     5341 cagtttcgta tatttctgaa aacggactaa taagatattt aaaacaaatg caatcagtaa
     5401 taaaatcatc acatctccaa aggtacggcc aaatgtctcc attaatccag catccacagc
     5461 attttgtcca aaataaggat ctgtaaccat ggcatccaaa ttgaaccgtt cctttagtcc
     5521 aaccaagatt ggccgaaaat tattgaccaa accaccagag ccaacagtca aaataaagta
     5581 accgaccgtt gcctttaaga atccagcgat gcattcatga agcgggcgtt tcagcaaaat
     5641 atagcctaat aacacgataa aaccaatcag gtatgctggc tgcgtcaaga tatttgttgc
     5701 aaaatacgtc caaatgctta acaaaaattc ccccatcttt tttctcctct atcaattaat
     5761 tatattctgc catcacaact tggtaatcat cgatggagtt cgtagagatg agacgctcaa
     5821 ccaatccatc tgtcattaat aattcggata atttttggat attttctaga tgttcttctg
     5881 gatcttttgc tgcgagtgta aaaaacaaac tagccgtttt ctcctcattc tccccttcac
     5941 tttcaaaacg gattggctgt ttcaacttgg taaatgaaat agctgttcca aaaacaccat
     6001 cacttttttc tgaagaatgc ggcattgcta cttgaggtgc gatcacaata taaggaccgt
     6061 atttttctac acaatggatg atctcctcca catacgtttc atcaataatt tccttatcga
     6121 tcaatacaag acagctttcg gcgatagctt cacgccaatc cgtgatttct ttatctgggt
     6181 aatgaatcaa ttgatggtca aaaaagtatt tcagcaagaa actccccttc tttcttataa
     6241 aaacgacgga aacggtgtat cattttcaat cgagaagaca tcttcaaatc ctcgataaaa
     6301 attaaactca agatcatctt tgtttgtcgg atagatgaat ttcccgccta cttgccagat
     6361 ataaggttta aatccatact tcaggcgatc ctttttgaat ttccaaattt cagtgatctc
     6421 ttttggatca gccataaaat tagaccaaat atcgtagtgg acaggaatca ctacttttgc
     6481 attcaatgac tccgccatgc gcagcatatc aacagaagta actttgtctg ttatccctcg
     6541 tgggttttca ccataggccc ctaaacagac atcgattttg tgttcattac catgtttggc
     6601 aaataaattg gagtaatgtg aatctcctgc atgataaaga ttccctcctg atgtttcgaa
     6661 taaatagttt actgcaattt gatccatctc ctgaggcatt tttcctttta atacctcttc
     6721 tggatcttca caagtgacca acgctgtccg atcaaacgct tctaaagcta ctacattgat
     6781 gtctttgatt ttgactgcat cacctggctt tactgtaatc gttttttctt caggaattcc
     6841 ccatttttgc cacgtgcgaa ccacttcttt tggcccaatg aatgttgctt caggacaatt
     6901 ttgatgaact gctgcggctg tatggatatc tagatgatcg gaatggatat gtgtaacgat
     6961 taaagcgtct acatttttta tcgcaaaagg atcgattacg aaaggctgag tacgtaaatt
     7021 aggctgcata ttttgaacgc cactcatacg catcatctga tggccttttt tcatcatgcc
     7081 attcccatga ctacgttttc ccgtcccaca ccatagatca cataaaatat tcgttccttc
     7141 atgacttttc agccaaattc ccgtacagcc cagccaccac atagcaaaag ttccaggatc
     7201 cactacttct gtttcgattt cttcattcaa gtatgtgccc cactcaggaa atgtttctac
     7261 taaccacttt tcttttgtta cttcattgac agttttactc atttgcttgc tccccccata
     7321 tcgttgttcc aacttacaag taaatattaa tgtgtatcag catccatgaa aaccctttta
     7381 tatgaccgtt tgttttttat atgattttct ttcagtaatc aatgattgtt tcagtataat
     7441 aaagacagat atgaatgttt aaatgaacaa ctagtcaaat aaatccatgg atcaagatgt
     7501 ccctcaggag gcaaaagtca tgaaaaactc acttgtcaat attgaaaaac gtcaaaaaga
     7561 aattttggaa ctgcttcagc agactgaaca actatcaact ttcgaattag ctgaatccct
     7621 tgatgtatct attagtacga tacgaagaga tttaaattta ttagaagaaa aaaacgagat
     7681 catacgcaat tacggttatt gttcttataa ttacaaaaac cagactgatt ttgatcaatc
     7741 tggtcctgaa aggattaaac aagcgattgc cagagaagct agtaaataca ttaacgatta
     7801 tgatacgctg tttatcaatt ctagctcgac tgcgttgaaa acactggatt ttcttcaatc
     7861 taaccatttg acagtcatta caaacaacgt gaaaatcaat tactctccgc acaaagataa
     7921 ttgtagttat attttaactg gtggagagat gcgctttcca aaagaagcac tagtgggcga
     7981 catcgcatta aatacgattt cttcagtcaa tgcagacatt tgtatcattg gctgtagcgg
     8041 agtcgatgta gtacatgggg tcacaacaaa gatattaaat gaatcaacga tcaacgaaat
     8101 gatggtcaac aagacaatca aatgtaagat tttagtcgct gatcatcgaa aaatcggact
     8161 gacatcaaag ttcaagattg ctgatatttc agtctttgat tatttgatca ctgataaatt
     8221 ttgttctgaa aaagtattag aggagatcag aaatacgggg ataaaaacca ttcaagtaga
     8281 ttcattttaa gaaccaggac gtaaatatgt aaataggatt atcaaaaaaa tgaataacaa
     8341 atttatcgat aaatgaaaaa cacgctacgc tcaaattgat aaaggaatcc caagatgtat
     8401 ccatccaatc gataccatca taatctattg cttcttttat aaccgttata tgttgcctaa
     8461 ataggaatca aacaatatcg aaaaaaggag gtatgacaaa agtcacacct ccttttttcg
     8521 aataaacggt attcaaatca gaacactgat ttcacaacca ctttatttca ggtcgttttc
     8581 aatcaccttt accgcgtaat catttccgtt gaaacgcgct attttttttg cgtccatata
     8641 tctttctaaa taatcatctt ctcctaattg cttatggcaa gaagcaattt cataaagcaa
     8701 gtattccaat gcataagtcg atttatgttt cttattatac tcaataccct tctcacataa
     8761 ttggattgct ttatcataat cctcgatttt acggtaatag gtggcgatat cataatatac
     8821 aatgcagacc atcagattat caaaatcagt ctcactcaat attttaagtg tacgctccac
     8881 ataaactttc gcaaaatcta attctccttt tgacaagtag atcattgcca cgtttgcagc
     8941 tgcttgtaag tgatggatat ctgtttcggt cgtttgttcc aacacttgat taaaataaaa
     9001 taatgctgca tctggttttt tcgcataaag atgatcaagc agtccttgat aaaataaaat
     9061 ttgatttaaa agatcagaat tacttacttt ttcctgatcg atcgtttgta aaattttata
     9121 agattcttgg tattttgata cagaattcaa tgattgaatc tcatttattt ttttcctgat
     9181 tttgtcttct tctgtttcta ctaatatatc ggagatctcg acattcagct ttttgcaaag
     9241 cgcacttaag atattgatgc ctggcgacat attcttgttt tcgatattgc tgacagttgc
     9301 ttgttcacaa atgccttctg ctaattgtac ttgtgttaac ccctttttct ttcggtattc
     9361 ttttagtaat gctccatcta ctttaatcaa aacaatttcc ttccctttaa aaaattattt
     9421 ctcctttata tcatacacaa aaaaaagttc taaacaacca aaaatgttta gaacagaata
     9481 aaaattttaa ttttaaaata atattcaaat taaacaactg gcgtatctgc tccttgattt
     9541 ctttttgtgt tatctgaata attatcgttt acagttataa cacatagtga aaattgtcat
     9601 ggcgagaaag tctaagaata tttttaaaca taactatttc tttcttacgt gtgtataatg
     9661 acgacagcac acctatcaat taatataatt attttatttt tttatgttct catgtttatt
     9721 tttaatgaca caacttctcg tatttatctg gcacaacata taaatcgatc aaaaaattgt
     9781 tgcgtgtttt tttgaaaatt ggagtttcaa cttgattaca aaatttaaat ttagaagttg
     9841 tgaaaacagc gagagacagt ttaatattca aaatatacat aggctactcg aacgctgtgt
     9901 tttttagtat actagtaaga aacgaaggga tagactcatt ccaataagga ggatttcatg
     9961 aagacaattc tttttgctcc tgcagtattc aatttagctg agacaacacg aatgattgag
    10021 gttgccaaag ctatgaaaga ccgttattac tgtgtattct ttggcttttc taaaactttt
    10081 gctcctttga tcacagaaag tggctttgag tatcatttac tagcgccgat ccttacgaaa
    10141 aaacaagaag aacaaatcat aaaatttgac cagttgcgta cacttaaaaa cccttttacc
    10201 aaagaaatgg ttgcctctcg tatcactagt gaacagagtc tgattgctaa gtttgagcct
    10261 cgactgattg tgacaggttc gaatgtgaca atttttttat cggcccgcaa taaaaagatt
    10321 cctttagtat atgttaaacc ctatgctttg agtgaacctt tttttcaatc agagcatgcg
    10381 ctgatgcccc acgagttacg tttcttcggc cctttaagca atcccctttg gcactggaca
    10441 aaaaagcgta tagtaaatac ccgatggatc cccaatgcct tcaaacacgc tgcacaaaaa
    10501 gaaatgcttc ctttaccaaa aacaagttta caaatgatgg atgctgatct aaatctcatc
    10561 acaacgccta aactattttt ggaagaagaa cagctgccgg aaaattatcg aatcgttggt
    10621 ccaatttttg ctaagctcag tacttccttg cctgaagaag tgctaacttt tatacagcga
    10681 aagcaacaag aaagaaaacg tattatctat ttcgcaatgg gtagttcagg caatccgcgt
    10741 atgttacgca aaattttgtt cttcttacaa aaacaaccgg atctagcggt tattgcacct
    10801 attgactatc tgcttgatga cattcaatct gactcagaag atcttttaat aacagaatat
    10861 ctgtctagtc atcttttgca tgaattcatt gatttttctt ttatccacgg cggggaaggg
    10921 accgtccaaa ctgcctgtga atccggcaaa ccgtttatcg gtgtggggat gcaatttgag
    10981 caaagctgta atattgacta ttgtgtaaaa tacggaaacg caatcgccct cacaaaacca
    11041 gtgactgaaa gaaaactgca gattgctctg cgcgaagttt cttcacccaa gattcgtcag
    11101 caggcacgca cgctgcaagc cgtttttcca ataaatggtc cacaacaagc aattcaagaa
    11161 atcgaaacct tcctgagcaa ccacccaata tagtttcaag tagaaaaagc ttttttaata
    11221 gagactcatc agtaatttcg ctattcgaga cccagacagt gaaaatacaa aaaaagtaaa
    11281 tagtggattg aaaagttaga gttacttaaa ttacggtgtc taaaaaacac aaaatcatcc
    11341 ttaaaataaa agatctgacg ctatccaaat gagcataggt agcgtctgcc atttattctt
    11401 agtcaaattc tttgacacct ttctctggtt ggatcatctc aacgtttctt caaaagaaag
    11461 accataataa ttaggcaaat acattttctt aaaatgtgtc atatagatct agaagcatcg
    11521 ctttgtagag atttgtgccg ctagtcccct caacaattac taaatcaaat gtaggattta
    11581 ccactttatc tttgataatc aacctccctc ttctgttgag acaatgatct cgcaatccga
    11641 tgcatactcc tatataaact gccagcaatc cccacatatt gagtagatca tgtcagaatg
    11701 ttctatgtcg tcagcaacga tacactaaaa gtcacgttca ccatgactga ttgctattcc
    11761 cagcacaatt atttctatac acgtttcatg atttgaataa acactcacat catacatatt
    11821 accattcata caccatactg cagcccctac tatatggttg taagctccca aatctatatt
    11881 tgacttgatc actttggtag tagatctact aattctaaat ccattgctga taaaatttcc
    11941 attttttcct ccttctttct gccaaaacag ttaaaacaat aataatcttt atgtaaaaaa
    12001 gggctgtgac aaaagccttg tcacagtccc atattccgaa taaacggtgg tcaaaagctt
    12061 gcatctgcgg taataagttc aaccaaacga aaaataagcc aacatttcac aaaaatttaa
    12121 gaagcaattt tcgtaaattt cttcttattt cttgaagcta accacttctg ttacaaccac
    12181 ttttagaaca tttaaagctt cgatgtgaca aaccatctat gctgctcgat cataaaattg
    12241 atagcaaaaa ttccacaaag tacatatgtc ccccatgaaa acaaaacatt catatgcggt
    12301 acaatgatct ttggaagaat cacgatcaaa aatgatgcca gtgcccaaat ccatcgattg
    12361 atttgaatat gatatgtagc tagcatattc aatataaggt gactagccgt taataaaaag
    12421 ataaaaacaa aaaataaaat cagccaatac attgtttccc accttctaaa aaccaaactt
    12481 agacagtctg gacttcgttt tctccacgac tttgttcatc tgacagcatc tttttatcat
    12541 aagcttttac aaatggataa tagataataa atgctatcaa tgtgttgatc atgatcaaga
    12601 taacaacacg ccagtcattt cctgctgaaa gataaccgcc gattggagct ggtaatgtcc
    12661 atgttggcaa aacagcaaat ctattgacca tttctaattt gactgcaaaa taactgataa
    12721 tagtcaaaac taaaggaact aagttgaacg ggatgaacat gtaaggattc aacatcatag
    12781 gagctccaaa aattatgggc tcattgatat tgaagatacc aggaataata gaaaaacgac
    12841 caacctcttt caagaatttt gatttacaga agaatataaa caaaacagat accacgatcg
    12901 ttgctcctgc accaccaatt gttaccgtcc attgataaaa ctgttcagga gcgatatagg
    12961 gtaattgggt ggcagctgta ccatctgcca atgcctttgc attctcatcc aacatgatca
    13021 gccacattgg acgaacaaca gcccctacaa tactcatgcc atggatacca aatgaccaca
    13081 acaaatggat caaaaacatt ggtagtaaaa caccaagcaa attattccct aaaatattgg
    13141 ttaaaggctc gaataacgat aataaggcag cgtttacatc aaagcccgcg acgcttcgaa
    13201 tcagccaagt aattgttaaa atgactgcac ctggaatcaa tgcctcaaaa ctacgggcaa
    13261 cagcaggtgg cacttgttct ggcattttga tagtaatatt tcgattttta aagaaacgat
    13321 atacttccac tgcaaaaatc atagataaga tccccgcaaa catcccagat gctcccaaag
    13381 aactcatagg taagacccag ccaagaggtg cctcttcagg agttaaaacg tttacaggaa
    13441 cttgtaacat aaagaacgtt cctaaagata atataccacc tgtcacacta tctaatccat
    13501 atgatttagc tagatccgaa cccataacaa aagttgcata aatagccatc aatcccatcg
    13561 tcatcctaaa gggtaaaaca atcgttgccg aataaggggc aataaattca ttccatccag
    13621 gaaacggtaa attgataaag accataaaaa atgtcccaat caaaatcaat gacaatgttg
    13681 aaacaacccc attacgaatt gctaataaat gacgctgtgt accaattttt gccattggtg
    13741 ggacaagttt ctcttcgacc catttcatca gcttttccac taaaaccact ccttttcaat
    13801 aaaatatgaa ccattcattg catgacaacg caaagaatgt tcataactaa ttatataatt
    13861 aagaaatttt atttcaatat attctcttaa ataatcaaat ttatttttaa gaatcctgaa
    13921 aataagtttt ctaaatcata ggagcaacaa aaaaattcga taattaacaa aaatcaaaat
    13981 gattaaatct agtgattgaa acatatcatt tcaaaaaaat tttgtaaatt cacccataaa
    14041 tatcacccta tttaactttt ttcatcgtac actaaaattc aaaacaacta tctttaatct
    14101 ttacttcttg gttttgtttt aataaatttc cttcaaaaat gcctggagaa actacaatga
    14161 tcaccgtatc tttttgtgct tgctccaact tcttcaaatc tataatagct aacagtgtcc
    14221 cttcttttac ctcctggtta ctttcaaccc gtatctgaaa cggacttcct tcgagttcaa
    14281 ctgtatctaa acccatatgg atcagtattt ttctgccaga ttcactttcg atcgttatgg
    14341 catgtcgggt aggaaatata ttatcgatta ttcctttaac tggcgcatgg atatatccat
    14401 catgattcgt tatagcgtat ccaactccta tcatttttga agaaaagacc tcgtctttta
    14461 ctgctgttaa tggaataatt tgaccactag ctacagcttt tagaatgttt cttgttttaa
    14521 agaaatgcac tttttatcac ctctacttta atgctggcca atattttttg tttactttga
    14581 tcatttcatc tagtattttt tttgcgactc tggcatttgg tacggtttga ttcaatgtaa
    14641 atgcttgtaa agctttttga taagaacctt caaagtaagc atctactagt aacttctcta
    14701 ctgcaacttg tgcctccatc aatcctttat gaaaatcact gattggtttt cttagtgtaa
    14761 ttggctccac accagttgca ccaacatatg ccggtatttc aacaactgca tctgaccgta
    14821 gattcggaat cgccccttga ttaggaacga ttagcataaa gcgacgacga tcatcattca
    14881 acaaggaaat agctatatcg acgatatatt gtccatgctc cccaaaatta aagttcaata
    14941 cttcttccac aataccgcgg cgtattttat cagccatttc tttggtattt ttctctcgtc
    15001 catccatgac catattagca cgtgtatact ctttgtcagt atgctcaacg accatatcag
    15061 gatataagta atactctaag taattattcg ggatattact tggaaaattt ttcgtgatga
    15121 ctgacatcat ttgaaaggtt ttttgccaag ttttatctcc tatattaaaa tcggcgactt
    15181 gcatttcttt tgttattagt ttttcaataa tctctggcat aatttctcgt tgcaattctt
    15241 tatcataaat cgatgtatac cagccaaagt ggtttaaacc ataatacgta acgatccaat
    15301 tcttacgatc ataaccgtaa ttcactgcaa tcgtttcttc aattgaaata gtcatatcac
    15361 aggcattaat catttttaca ttcggatatt tacgacgaac agcttcagaa acgatcgact
    15421 ctggatttgt ataattcaaa atccatgctt tgggggcata gtcttgtata tgatcgacaa
    15481 tttccaataa acctttgatt gagcgcatcc cataagcaaa tcctccgagt ccacacgttt
    15541 cttgtcctac taatccatgt ttaagtggaa tcttttcgtc cttttctcgc atctccaatc
    15601 ctccaacacg aatttgtgag aaaacaaaat cgcgtcctgt aaaagcaagc tttggatcat
    15661 ccgttgcacg aatgcgaata tttgaaaaac cttttctttt cagcataaat ttaacaatca
    15721 agtacatatc catatttctt tcttcatcaa tatcatataa acgtatttca gataatggca
    15781 accgtttttc attgttcaaa atggcttgaa cgattcctgg tgtatacgta ctcccgcctc
    15841 cagctatagt gataatctgt tttttcatca tcatcttttc ctttctattc ttctaataat
    15901 ttattgaatt ctgccataac ataagtcact tctaagccga tgataatttg ataatttttt
    15961 tcagttggtt taatgatccc gcttatccct aattgcttga ttcgctgttc ctcgaccatg
    16021 gtgggatcca ctacctctac ccgtaggcgt gtattacaac tatagacatc caggatattg
    16081 gcttttcctc caaacgcttg tagcattttt gttgccatat attcataatt tttacttgct
    16141 aaccctaact ctgtttcttc taaggttact tcattgccaa actctgcctt agcttcacgt
    16201 cctaatgtct gaatgtttct cttattgatc aaataataaa aagtaacgta atacaaggca
    16261 aaaaagaaaa ttccgattgg aagaatcaaa atagcattgg tagcgattcg aaaattgatg
    16321 agataatcaa caatacatgc tccgaatgta aaaccaattc gtatattgaa taagtaacag
    16381 acaatccctg ctaaaccggc aaaaagtgca tggatcacgt acaacatagg agaaagaaac
    16441 atgaaactaa attcaacagg ctcagtgata tttgcaataa atgaagttcc tgcaccgctt
    16501 cccatgattc ctttgaccat ctctttattt tctttataag ctgctttata gatagctaga
    16561 catatagctg gtataccaaa catcattact acaaaaaaaa ctgataaaaa cagtccagcc
    16621 tgaggatctc cgttgataaa gcgtgtcatc tctcctctga aaacttcctt gctaggagat
    16681 gtatagcttc ctaaatcgta ataaatatac gtattcaaca catggtgcag tccaaagggg
    16741 atcagcaaac gattcaaaaa cataaatatc cccacaccta atgctcccat atcaacgagc
    16801 agttttgcaa aattatcaat cccaatttgg atgagcggcc agataaagcc caaaaaaaca
    16861 gctgcgattg tttgtagaat catcaccata gtcaatggga atttttcgcc cgcaaaataa
    16921 gaaaaaacta ctggtaattt ttgttcttta aagcgattat acgtccatgc cgctactaaa
    16981 ccggaaataa ttccaccaaa aatccccata ttcacttctg ggtccataat ttctaagcct
    17041 tttttcaagg tagcaatcgc taaaaaacca gtaagtgcag gtattccttt gtccttattt
    17101 ttgacaaaac cgattgcaac tcctatagca aataagatat ccaagtttcc aaaaacggca
    17161 tttccagctg caccaattac tgggatgttc agcatatcgt cagctgataa acgcatgatc
    17221 aatcccgcta atggcatcgc tgcaactgga agtagcatcg ctcttccaag cttctgcaca
    17281 tttgatttaa cattcatttt tattcctcct ctattaaata tcctcatatg ttactaactc
    17341 aatcaaagga tcatttttca ctttttgagc aaatgctgaa tgaattaaaa attcgacttg
    17401 gtgggtacga ggatacacaa aacttgaacc atttaacaat tcctgatcca aatacgctgc
    17461 gtgacacatg acttcgatcg ttttatcttc tctcaatatc atgagtaaac ttgccaaata
    17521 ttcttccaca ctcgtattga tttgtcgttt tttttcatca gtttctccta cgacatcgaa
    17581 acaaggctca aaataatcga catgacgaac ttcatctttt cgttcaaagt tgctccgaac
    17641 cggcaaatca tatttttttg ctaatgtaac aactacctcc tgattttcat ccaaagtatg
    17701 agtatgatga tgactgtcta aatgagttgg tatgatcccc gcatgataaa ttttttgaat
    17761 ctgagcattc cattcctgat acagttgatc tttgtcaatg ttaaatggat gctgataata
    17821 agataaggat ctgaactctc cgctttcgat aagagtatcg acagttttga ggagtggttt
    17881 gccacacgtc aatgttaaat ggactcctac acctagccta ggcatttcct ttcttagttt
    17941 cacagcatgc tcgaaacccg gcatatttgc catcaatgta gttgatgtca aaattcctcg
    18001 ctgataagca tccataatcc cataattcac accatggcta tagccaaaat catccgaatt
    18061 aaaaatcact tttcccattt cattctcctt cttttttcta ctaaaatagg cgcaaccaaa
    18121 taatcatagt ccatttacta tgtgtcattt ggttgcgcct atagatagtt acgcccttat
    18181 tttaatagat tcttgctaga tgaattgcca aatagatgat ttcattttct tgaatggcaa
    18241 gttgaaattg ctgttcgatg atatctttaa tctttagtgc tgtacaatac gctttgctat
    18301 gtttaaatgt ttcagtaaaa aaaccaatat tttctactgg cgtttcttcc tgataaatca
    18361 agcgtttaac caggaatttg atatgaacca ttaagcgatg ataagtcagt gattctttat
    18421 cataaacgtt tgaataggat ttttctagat gggacaaaat cgtggtcgtc atttctacta
    18481 tttttaagct ctttaaacta ttaggctctc ctagctcagc attaatgata tgcatagtga
    18541 tgaatcctac ttcatttgac cctaactcgg tttgatatcg atgattgatt cgctcgacca
    18601 cttctactgc tatatcatat tcatttggat aaaggaatct catttctggc aacataattg
    18661 ctgtgacatc tctatcttct ctttttcgtt gaatagcaaa ataaatatga tctgtcaatg
    18721 taatatagat atttgaatct aatggagagg agatcctagc tgttatcagt tcaatcactt
    18781 cttccgcaaa atccataaat tcgattggaa tctgcgagac tatctcactg aatcgtttga
    18841 tcttttcttt agaatctaat acaaataatt tgtcagcatc ctcaacatca aatggcttac
    18901 tcactttagc agaaaagcca atccctttcc ccatcgcaat tttttctatt ccatcgtcat
    18961 cgatcaatac agcattatga ttcagctttt tcatcacata caccgttaat tcacctcctc
    19021 tatatgataa aacaaaacaa cttgcagact ccttcataca tatttttgtc tccaaacaat
    19081 ttttaaagac aaaaaacgac ctaagaaaga accctttctt aggtcgtgcc taattgaata
    19141 gtagcaccct acataattta caaaaatagt ttaacacata ataaaagcgt tatcaatatc
    19201 ttttttactc gttttatgat aatacttgta tcgaattgat ttggaggtaa ttacataaaa
    19261 acaaaaaaaa tatagcaact ctctataaga aagttgctat attgataatt ataccggcgg
    19321 ccggggtcga accggcacgt cctcaacgga cactggattt tgagtccagc gcgtctgcca
    19381 attccgccac gccggcaaat ttaaaaataa taactggggt agctggattc gaaccaacgc
    19441 atgagggagt caaagtccct tgccttaccg cttggctata ccccaagaat aaagggcgaa
    19501 tgatgggaat cgaacccacg aatgccggag ccacaatccg gtgcgttaac cacttcgcca
    19561 cattcgccat cataaaagat gttatttaat ttctcaataa aaaactaaga tgaagacatc
    19621 ttagtcaata ccggcggccg gggtcgaacc ggcacgccct caacgggcac tggattttga
    19681 gtccagcgcg tctgccaatt ccgccacgcc ggcaagttga tttattagta ctaaggcggt
    19741 aaccggattt gaaccggtga tgaaggtttt gcagacctct gccttaccac ttggctatac
    19801 cgccattata ctattatcaa tctataaaat aaagaataaa ttatagaaac tggggtagct
    19861 ggattcgaac caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc
    19921 aagaataaaa agggcgaatg atgggaatcg aacccacgaa tgccggagcc acaatccggt
    19981 gcgttaacca cttcgccaca ttcgccatgg caggggcagc aggaattgaa cccacactaa
    20041 cggttttgga gaccgctgtt ctacctttaa actatgcccc tataaaatgg aggagagtgg
    20101 attcgaacca ctgaacccta aggaacggat ttacagtccg tcgcgtttag ccacttcgct
    20161 actcctccat ggtggcgcgg gacagaatcg aactgccgac acacggagct tcaatccgtt
    20221 gctctaccaa ctgagctacc gcgccatatt ttaaaattat taattgaata acaagaacga
    20281 cggttccgac gggaatcgaa cccgcgatct cctgcgtgac aggcaggcat gttaacccct
    20341 acaccacgga accagttcat tatggaggtt aacgggatcg aaccgctgac cctctgcttg
    20401 taaggcagat gctctcccag ctgagctaaa cctccaacat tcaattaaaa tgacccgtac
    20461 gggattcgaa cccgtgttac cgccgtgaaa gggcggtgtc ttaaccgctt gaccaacggg
    20521 ccaggtaaat ttgctacgga gagtaaggga ttcgaaccct tgagacagtt tggcaccatc
    20581 tacatgattt ccaatcatgc tccttcggcc tctcggacaa ctctccagag tgaaagaagc
    20641 tcaatactct ttctcaaaat gag
//
LOCUS       DARPZJ010000043        20656 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.045, whole genome shotgun sequence.
ACCESSION   DARPZJ010000043 DARPZJ010000000
VERSION     DARPZJ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.045"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(18..1574)
                     /gene="rny"
                     /locus_tag="SLE23_001963"
     CDS             complement(18..1574)
                     /gene="rny"
                     /locus_tag="SLE23_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEI8468849.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(1985..3034)
                     /gene="recA"
                     /locus_tag="SLE23_001964"
     CDS             complement(1985..3034)
                     /gene="recA"
                     /locus_tag="SLE23_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEI8468850.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3143..4384)
                     /locus_tag="SLE23_001965"
     CDS             complement(3143..4384)
                     /locus_tag="SLE23_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEI8468851.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(4624..5202)
                     /gene="pgsA"
                     /locus_tag="SLE23_001966"
     CDS             complement(4624..5202)
                     /gene="pgsA"
                     /locus_tag="SLE23_001966"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEI8468852.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(5411..6334)
                     /locus_tag="SLE23_001967"
     CDS             complement(5411..6334)
                     /locus_tag="SLE23_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468853.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(6951..8237)
                     /locus_tag="SLE23_001968"
     CDS             complement(6951..8237)
                     /locus_tag="SLE23_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEI8468854.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(8230..9498)
                     /locus_tag="SLE23_001969"
     CDS             complement(8230..9498)
                     /locus_tag="SLE23_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEI8468855.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            9750..10211
                     /gene="mscL"
                     /locus_tag="SLE23_001970"
     CDS             9750..10211
                     /gene="mscL"
                     /locus_tag="SLE23_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEI8468856.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(10270..10716)
                     /locus_tag="SLE23_001971"
     CDS             complement(10270..10716)
                     /locus_tag="SLE23_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8468857.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(10809..11054)
                     /locus_tag="SLE23_001972"
     CDS             complement(10809..11054)
                     /locus_tag="SLE23_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEI8468858.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(11168..11746)
                     /locus_tag="SLE23_001973"
     CDS             complement(11168..11746)
                     /locus_tag="SLE23_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8468859.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(11823..12353)
                     /locus_tag="SLE23_001974"
     CDS             complement(11823..12353)
                     /locus_tag="SLE23_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEI8468860.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(12357..13217)
                     /gene="rlmB"
                     /locus_tag="SLE23_001975"
     CDS             complement(12357..13217)
                     /gene="rlmB"
                     /locus_tag="SLE23_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEI8468861.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(13210..13605)
                     /locus_tag="SLE23_001976"
     CDS             complement(13210..13605)
                     /locus_tag="SLE23_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEI8468862.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(13602..15014)
                     /locus_tag="SLE23_001977"
     CDS             complement(13602..15014)
                     /locus_tag="SLE23_001977"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEI8468863.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(15011..15547)
                     /gene="cysE"
                     /locus_tag="SLE23_001978"
     CDS             complement(15011..15547)
                     /gene="cysE"
                     /locus_tag="SLE23_001978"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEI8468864.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(15633..15872)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15869..17329)
                     /locus_tag="SLE23_001979"
     CDS             complement(15869..17329)
                     /locus_tag="SLE23_001979"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEI8468865.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(17499..18656)
                     /locus_tag="SLE23_001980"
     CDS             complement(17499..18656)
                     /locus_tag="SLE23_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HEI8468866.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(18690..20060)
                     /gene="radA"
                     /locus_tag="SLE23_001981"
     CDS             complement(18690..20060)
                     /gene="radA"
                     /locus_tag="SLE23_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEI8468867.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(20123..20650)
                     /locus_tag="SLE23_001982"
     CDS             complement(20123..20650)
                     /locus_tag="SLE23_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEI8468868.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         5437 a         4562 c         3687 g         6970 t
ORIGIN      
        1 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
       61 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
      121 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
      181 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
      241 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
      301 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
      361 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
      421 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
      481 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
      541 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
      601 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
      661 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
      721 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
      781 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
      841 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
      901 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
      961 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
     1021 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
     1081 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
     1141 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
     1201 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
     1261 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
     1321 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
     1381 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
     1441 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
     1501 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
     1561 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
     1621 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
     1681 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
     1741 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
     1801 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
     1861 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
     1921 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
     1981 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
     2041 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
     2101 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
     2161 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
     2221 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
     2281 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
     2341 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
     2401 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
     2461 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
     2521 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
     2581 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
     2641 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
     2701 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
     2761 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
     2821 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
     2881 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
     2941 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
     3001 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
     3061 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
     3121 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
     3181 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
     3241 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
     3301 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
     3361 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
     3421 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
     3481 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
     3541 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
     3601 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
     3661 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
     3721 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
     3781 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
     3841 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
     3901 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
     3961 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
     4021 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
     4081 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
     4141 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
     4201 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
     4261 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
     4321 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
     4381 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
     4441 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
     4501 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
     4561 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
     4621 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
     4681 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
     4741 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
     4801 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
     4861 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
     4921 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
     4981 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
     5041 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
     5101 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
     5161 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
     5221 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
     5281 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
     5341 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
     5401 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
     5461 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
     5521 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
     5581 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
     5641 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
     5701 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
     5761 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
     5821 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
     5881 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
     5941 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
     6001 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
     6061 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
     6121 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
     6181 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
     6241 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
     6301 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
     6361 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
     6421 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
     6481 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
     6541 caaaagcttg catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt
     6601 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg
     6661 tgttccagaa gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat
     6721 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta
     6781 cttcgtttga ttttatttta atataagttg attaaaagag agcatgattt gttttatttt
     6841 ctcactaatt tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc
     6901 tactacaagt ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt
     6961 ctcatgtaaa actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg
     7021 tctttcattt ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat
     7081 aaactttgcg taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt
     7141 ccaagcattt tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg
     7201 aatccaagaa tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg
     7261 ctgaagtccg caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg
     7321 ataattcctt gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg
     7381 aacaacagat tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg
     7441 tctaatcctt taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt
     7501 tgtttgatga tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg
     7561 aaattttttg cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta
     7621 ccaactacaa ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag
     7681 tcttgagctg tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg
     7741 tgtgtaggat acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca
     7801 tacatttgga tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag
     7861 taaggtgctt gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta
     7921 gaaaacagat agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc
     7981 ccaaataatt gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg
     8041 gcaattccat ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg
     8101 atcgaaccat aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac
     8161 aaatacacgg tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca
     8221 tattctgttt tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat
     8281 ttgctcagct acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc
     8341 ttcatcagat aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc
     8401 ttgcggagag tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag
     8461 ttccaactct gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag
     8521 tacttgattt cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt
     8581 atccacgcta ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag
     8641 tttagagtga ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg
     8701 ttcatcgtaa tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc
     8761 acgtacttgt cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata
     8821 aactgtttcc cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc
     8881 aacatcgccg acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga
     8941 cgctagcgaa ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt
     9001 ttgttccggg ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt
     9061 atcttccttc aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa
     9121 ctgatcaaac tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac
     9181 cgcttgagaa aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc
     9241 gtttagccaa tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag
     9301 ctctgcaagt tgcgcactta actttgtctg atccggataa ttcaaactat ttgtttccaa
     9361 catgctgctg agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg
     9421 gataaaaatc cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc
     9481 tgccaattga tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt
     9541 ttaatgggtc aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca
     9601 attcgccgtt ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca
     9661 aaagaaacag acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta
     9721 aagacaaata aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc
     9781 gtggagatgt cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg
     9841 taaaccaagt ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca
     9901 caggtacttc tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg
     9961 tcacatttgc gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg
    10021 tcttattctt agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc
    10081 aagtggaagt ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc
    10141 ttgccaaaca agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata
    10201 cttctaaata ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt
    10261 tttagattct taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc
    10321 caaatacaca tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc
    10381 ttgtgcgccg atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc
    10441 ttgaacaatc tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc
    10501 aaaatggata ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt
    10561 atcttgaaaa aacgtatgcc aagcttgtcc atcaatgtca tcaacttctt gataaggaca
    10621 ctgttgttcc acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt
    10681 tgacaattct tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt
    10741 attcttagca taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg
    10801 tttgcttttt aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct
    10861 gaatagctgt aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat
    10921 actgaaggat aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc
    10981 tgagcaacca acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct
    11041 aaagttgttg gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt
    11101 caagtttacc ataaaaaaaa agaaatgcaa taaaaataaa taagaagctc attaagattt
    11161 ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc
    11221 cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat
    11281 caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc
    11341 aattttcgat tgcttctttt aataaaagat gctgaatcgc taaaggttct tgcaatgtga
    11401 tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt
    11461 tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta
    11521 taatgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg
    11581 cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat
    11641 aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg
    11701 cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc
    11761 ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata
    11821 tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct
    11881 tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct
    11941 attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct
    12001 ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc
    12061 aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct
    12121 ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt
    12181 tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga
    12241 tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc
    12301 ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac
    12361 tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt
    12421 aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat
    12481 cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc
    12541 catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg
    12601 agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc
    12661 ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc
    12721 acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct
    12781 tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc
    12841 agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg
    12901 ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt
    12961 tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag
    13021 agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa
    13081 ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt
    13141 ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt
    13201 gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc
    13261 catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc
    13321 gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc
    13381 tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat
    13441 caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg
    13501 ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc
    13561 aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat
    13621 cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt
    13681 tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt
    13741 tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat
    13801 tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga
    13861 taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa
    13921 tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc
    13981 gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta
    14041 ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc
    14101 ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg
    14161 atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg
    14221 ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc tgttttcgct
    14281 tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg
    14341 atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg
    14401 ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat
    14461 aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct
    14521 ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg
    14581 gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga
    14641 ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggctcg
    14701 acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt
    14761 gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc
    14821 gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca
    14881 atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac
    14941 ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg
    15001 tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg
    15061 gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga
    15121 ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg
    15181 ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta
    15241 cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca
    15301 ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag
    15361 ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata
    15421 aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct
    15481 cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc
    15541 aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa
    15601 gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac
    15661 ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac
    15721 tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag
    15781 gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca
    15841 gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg
    15901 atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg
    15961 atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa
    16021 cagctttgat ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg
    16081 ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt
    16141 cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat
    16201 agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat
    16261 ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg
    16321 catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga
    16381 aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt
    16441 cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg
    16501 catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac
    16561 gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg
    16621 gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt
    16681 catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat
    16741 tataagttgg cataccatcg cgtttttgta tgacaaagtc gccaccgata ttatcggatt
    16801 cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac
    16861 ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca
    16921 agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt
    16981 ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct
    17041 gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc
    17101 caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc
    17161 ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt
    17221 ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat
    17281 gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct
    17341 tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat
    17401 catttattta aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa
    17461 ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt
    17521 ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc
    17581 atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg
    17641 taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt
    17701 tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact
    17761 ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag
    17821 actttattca agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg
    17881 atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat
    17941 ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt
    18001 ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc
    18061 atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc
    18121 acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt
    18181 tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact
    18241 ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc
    18301 atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc
    18361 gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa
    18421 gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg
    18481 gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta
    18541 ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa
    18601 atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt
    18661 tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc
    18721 aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt
    18781 ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata
    18841 tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc
    18901 tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct
    18961 ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc
    19021 aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct
    19081 gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc
    19141 aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg
    19201 cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt
    19261 tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga
    19321 aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt
    19381 cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca
    19441 tttgttttag cgattttgag tagttctgca gtggtttctc ttacttggct gacacttcct
    19501 gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca
    19561 ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa
    19621 aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct
    19681 tcgccggata catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac
    19741 agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc
    19801 acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt
    19861 ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga
    19921 gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa
    19981 tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt
    20041 acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc
    20101 aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag
    20161 cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct
    20221 cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc
    20281 cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca
    20341 ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc
    20401 ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg
    20461 atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc
    20521 agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg
    20581 tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc
    20641 tttttctcac cggttt
//
LOCUS       DARPZJ010000044        20281 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.046, whole genome shotgun sequence.
ACCESSION   DARPZJ010000044 DARPZJ010000000
VERSION     DARPZJ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.046"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            136..456
                     /locus_tag="SLE23_001983"
     CDS             136..456
                     /locus_tag="SLE23_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468869.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            908..1108
                     /locus_tag="SLE23_001984"
     CDS             908..1108
                     /locus_tag="SLE23_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8468870.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1255..4044
                     /locus_tag="SLE23_001985"
     CDS             1255..4044
                     /locus_tag="SLE23_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEI8468871.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4091..4618
                     /locus_tag="SLE23_001986"
     CDS             4091..4618
                     /locus_tag="SLE23_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEI8468872.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4639..5829
                     /locus_tag="SLE23_001987"
     CDS             4639..5829
                     /locus_tag="SLE23_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8468873.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5869..7167
                     /gene="asnS"
                     /locus_tag="SLE23_001988"
     CDS             5869..7167
                     /gene="asnS"
                     /locus_tag="SLE23_001988"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEI8468874.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8220..8894
                     /locus_tag="SLE23_001989"
     CDS             8220..8894
                     /locus_tag="SLE23_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEI8468875.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8891..9232
                     /locus_tag="SLE23_001990"
     CDS             8891..9232
                     /locus_tag="SLE23_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468876.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9262..9621
                     /locus_tag="SLE23_001991"
     CDS             9262..9621
                     /locus_tag="SLE23_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEI8468877.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10145..12226
                     /gene="cadA"
                     /locus_tag="SLE23_001992"
     CDS             10145..12226
                     /gene="cadA"
                     /locus_tag="SLE23_001992"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEI8468878.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12537..14003
                     /locus_tag="SLE23_001993"
     CDS             12537..14003
                     /locus_tag="SLE23_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8468879.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14618..15157
                     /locus_tag="SLE23_001994"
     CDS             14618..15157
                     /locus_tag="SLE23_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEI8468880.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15231..15671
                     /locus_tag="SLE23_001995"
     CDS             15231..15671
                     /locus_tag="SLE23_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEI8468881.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15684..15893
                     /gene="copZ"
                     /locus_tag="SLE23_001996"
     CDS             15684..15893
                     /gene="copZ"
                     /locus_tag="SLE23_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HEI8468882.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALYGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15893..18079
                     /locus_tag="SLE23_001997"
     CDS             15893..18079
                     /locus_tag="SLE23_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEI8468883.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18099..20270
                     /gene="copB"
                     /locus_tag="SLE23_001998"
     CDS             18099..20270
                     /gene="copB"
                     /locus_tag="SLE23_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HEI8468884.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6773 a         3527 c         4406 g         5575 t
ORIGIN      
        1 agaggttgtg acgtggtcac gacctctttt tgacgattat gatacaaaaa acatcattta
       61 tgaacaaaat gtgaataacg ggcgttcttg agatatgatt ttaattggga aaaacttatc
      121 gataaggagg tctttatgaa aaaaagactg ttatggtgtt tgctgtttct atccctaagt
      181 ttaacaagtc agccagtttt tgctgaagaa acacagcggt ctcctattac aggcacacgt
      241 ctgtacaaaa atgtttatgt acagacaaca gatcttgatt ctgcgattcc tgaaacagaa
      301 gaacggtctt tgcagccaag atttggttac ttttggtact gtccgacctg tgattatgaa
      361 agttgctggc atttcttaca ttctacagct gcagcttttg cttttactca tactcagaaa
      421 tatgatggac atcatcctgt tatttatgag gtatagatat gagcaaaaaa gaaaaactaa
      481 tctcgttgat cgtattggtt tgccttgttc ttctggtaac tgtcataggc tatcagaaat
      541 accatgagaa catcagacct actaaagaat cttccccagc ctcgaccgtt gaaacagaac
      601 cgataagtag tcagaaagaa taattttttt agtttaaaga agaacatcag agcaaaaaaa
      661 caccaactga acaatatgtc gtttatttta aaaaaagttc ggtttttcac tttatgtaat
      721 cgctgagaaa acttttttta ataaaaaaag tcgaaaaact ctagcttttt tgtaaacggt
      781 atgatatact ataggagtag tttttgttcg gtaatctgtg gtagcttgtt tcaaataaac
      841 atcttccaga tatacaccat tcaagtaatt gcaaaatatg tgttgataca caaggaggat
      901 ttttattatg gaaacaggta cagtaaaatg gtttaactca gaaaaaggat ttggattcat
      961 cactgcagaa aacggaaacg atgtattcgt tcatttctca gctatccaag gcgacggatt
     1021 caaaacttta gaagaaggcc aagcagtaac tttcgatgtt gaagaaggcc aacgcggacc
     1081 tcaagcaaca aacgttacta aagcttaatt aacctatact aaaaaataaa cgcccagaca
     1141 tttgcgtgtc tgggcgtttt tgtctatttt ctttaaaaag cgatgagagt atttttctgc
     1201 actttgtagt ataatttcaa aagaacatta gaggcaggag aagaggaaga tattttgaaa
     1261 ccaagaactt atgcagtcgt tgatatcgaa acgactggga cgaatccaaa agaagatcgg
     1321 atcatccaat ttggctgcgt catgattgaa tcaggtcgga tcacttcacg tttttcgatc
     1381 gatattcatc cagggcggaa gatttcaaaa caaatccagc atttaacagg gatcacgaat
     1441 caacgcgtcc aaaaagcgcc ttatttcgaa gatgtcgccc aaacgattta caatcttttg
     1501 gcagacacca tatttgtcgc gcataatatt tattttgatt ataatttttt gaaccatgaa
     1561 ctcatgcgat gcggacttcc tagtttgaag ataccaggca tcgatacagt agaacttgca
     1621 caaattttct tgccgacgga accaagcttt cgcttagctg atttgtcaga aagccttgga
     1681 tttattcatg agaatcctca tcaggcagat agtgatgccg aagtgacggg tcaacttctt
     1741 ttgctgatcg aagaacggat gagaaaattg ccaatcatca cgttagagca gattgcgcga
     1801 ttaagtagac acacaggtat ggatacgagt cgtttcattt atcatgtgat tgaagaaatg
     1861 aaagaaaaac cagagccact tgatccctca ttagaaatcg tcgatgggct agctttgcag
     1921 aaaaaagaag tggaactatt cacatccgtc cattatggcg agcggacata tccaagaaaa
     1981 aaacaagcaa aagaaaaaat gtttggtaaa acactgatgt atcgaaaaga acagaacaga
     2041 ctgatgaatg cggtctacga ccatttcaca aaagatgaat caaaagattt gatgatcgaa
     2101 gcagctacag gaatgggtaa aacaatcggt tatctgctgc cattgagtta tttggctaca
     2161 cctgaaaaac ccgctgtcat cagtaccgtt tcgctagttt tgcagcagca gatcatagaa
     2221 aaagacattc cattgctgaa tcaattgcta gatcagccca tacaacctgt aattatcaaa
     2281 agctatcgcc actatattga tttacagcgt tttaaaggca cacttgtgga accgccagaa
     2341 caaaaacaat atgctttgta tcaaatggcg gtcttagttt ggctgacgca aacgaagacc
     2401 ggtgatttgg atgaattaca tttaacaaat ttgaaccatt cattctttgc agatatcgcg
     2461 cacagaggta ttggattttt agcaagaaat cagtcatttt acgaacaaga ctttgttcgt
     2521 ttcttgcaaa agaaaatcag gcaaagtaat tttttgattg tcaatcatgc gtttttaata
     2581 caagaaacac agcgaaaaga accattgctt ccagctagtc catttttgtt gatcgatgaa
     2641 gtacatcatt tgccggaaat cgctgaaaaa gtaaatgaca aacgattaag tattaactat
     2701 ttccataaac aaatccagca attagaagaa ccaaatcagc tgtttgaccg aatacaaagc
     2761 tatttaccga aagaacatga agccttacgc tggttatcga tttatcgaga agaactttct
     2821 gcgctatgcg aagcacagat ttgtatggca gaaggattaa tgagtttagt gagcggcaag
     2881 caacctaacg gacagtatcc agaagaagtc atgatgacaa aagagatgtt ggatcagctg
     2941 ccactggaat ctgggacagc cattgatcac ctgcagcttt tttatcagga gatccagcag
     3001 ctacagtcac aaatgcgtct gacttttgag attatccaag aaagctggac aaaccagatg
     3061 cggatcgatt tagcaagttt atatagctta tttgatcaat tagacaagca gtacttgctg
     3121 atggatcaat ggctggaaga ctggcgagat catttgatcc attggttcgt tcctgggaac
     3181 acagcgcagc agatgatttt tcatctccat gattttcaag cggctatgtt gccgtcgact
     3241 gtttggtatc ctcgatatga tcgtattctt tatattggag gaacgctgaa gatcggccct
     3301 aatcgacact atctctctaa gcggcttggc attgaagcag cacctcttaa agtgattgcc
     3361 tctccttatg attatgagaa acaggcaagg atctatgtgc caaaagaggc acctgccgtc
     3421 catcaagtca gcaatcaagc atatatcgat tatttagaga cagcacttac aggtctgatc
     3481 gaacaagaag atcggccaat acttgtgtta ttcacttctc atgatgtttt gcagaaggtc
     3541 tatcagaaaa tgcatctgtc tatgctagaa aaaggacgag aaatactagc tcaagggttt
     3601 ggcggaagcc gggagaagct tttgaaacgc ttcattttgt cagaaaaaag cgtattgttt
     3661 ggcgctgaca gcttttggga aggtgtagat ttgcctgggg atgctttgca gatcgttgta
     3721 gtcacacgtt tacccttcga taatccgctt cgcccgatgg tcaaagctag gaacgcttat
     3781 ttagaatcag aggggatcaa tcctttttac caggaatccg tacctaaagc agctttgaag
     3841 ttacgccaag cattaggtcg cttgataagg acggagacag atcgtggcgt attgcttatt
     3901 ttggatcgaa gactagtcac tgcaaaatat ggtgcacgga tcatccatgc attaccgaaa
     3961 aaagtaccga tcaaagagct agctatggag gaaatctatc aggacatcca tgaattctta
     4021 aagaaaaatg aagaaggaag ttagaggagc tgtctttttt cataattaaa atctgctata
     4081 atgaaaagga atgaagataa aggagcgacg acccttgaag aaaaaacaga caaaggaaaa
     4141 aacgattaat cgcgtgttac ttggcttgat cgtattttta ttagcggtca tcgtgatcag
     4201 ctcgattttt tacttgcgtt ccagtcgtcc ggcggtgcag gcgaagaaag aagcagtaga
     4261 aatcgcaaag aaatatgcaa atcttgagga agccgatcat ttttattggt ttactcgaaa
     4321 gaagacatac ttttcactga caggtacaaa tgataaagga aaagaaatcg ccgttatcat
     4381 tcctaaatct ggtgaaaaag taaaagtatt ggatcaaaca aagggactga ctgaaaacga
     4441 agcaaaacag acaattgctg cggcccatcc tgaaatccaa atcgaaaaag ctgctttagg
     4501 gatgtatgat gatcagcctg tgtgggaagt agtaggaaaa gaaacaaatg ggaaactgaa
     4561 ttattacctg attggctttg aatctggaga tgaagtcaag acaatcaagg gaatttaaaa
     4621 ggtaaaggaa tgaatgggat ggagttatca aaaagaacaa aacgattaga accgtctgtc
     4681 actttggcag ctgcggcaaa ggccaaggca ttaaaagcaa aaggcagaga tgtgctgagt
     4741 ttgactgtgg gagaaccgga ttttgcgaca ccagaaaaca tccaagaagc agcaatcgaa
     4801 gcaatccgca acgggaaagc tagctattat acaccaacag caggaatccc agagcttcga
     4861 caggcaatcg ttgattatct gaagaaaaac tatggacttg tctatgaacc ttcacaaaca
     4921 gtcgtaacag acggagcgaa atttgctttg tatacccttt tccaaacgat ccttgacccg
     4981 caagatgaag tcatcattcc tgtgccttac tgggtcagtt acggtgagca agtaaaactg
     5041 gcagaaggac ttcctgtctt tgtgaaaggg gaagaatcca atagctggaa agttactgtt
     5101 gaacagctag aacaagcacg ttcagaaaaa acaaaagccg taatcatcaa ttctccatcg
     5161 aatccgactg gaatgattta tagcaagaat gaactgcagg caatcggtga atgggcagta
     5221 aaaaatgata ttttgatagt tgctgatgat atttatggtc gtttagttta taatggcaat
     5281 gagtttactc caattgcaac gatttcagaa gcaatcaaaa atcagactat catcatcaac
     5341 ggcgtgtcta aaacatatgc gatgacaggc tggcgcattg gttatgcggt gggaaatcct
     5401 gtgatcatca atggaatgat cgctgttgct tcccagtcaa ccagtaatcc gacagcagtc
     5461 agtcaatatg cagctgttga agcattgaaa ggcgagcaag atacagtgga agaaatgcgg
     5521 aacgcctttg aagaacgcct gaatacgtta tattcgcttg tggcagaact gccgggtgtt
     5581 tctcttgaaa agccacaagg agctttttat ctttttccta atgtaaaaga aacgctacgc
     5641 atgtgtaaat atgaaaatgt cacacaatgg gtagaagatc ttttagaaga aacaggggta
     5701 gcgcttgtga ctggcgaagg ctttggggca ccagaaaatg tccgcatgag ttatgctact
     5761 gatcgcgcta cgttagaaga agcggtacgc agaatcaagc aatttattga gagtaaaagt
     5821 caaaattaat cctaaagaaa ttcaaggaat ataaaaggag agtcatacgt ggaacaaatt
     5881 caaatcatcg attcgaaaaa ccatgtggga gaaacagtaa caatcggcgc ttgggtcgca
     5941 aataagcgat caagcggaaa aatcgcattt ttacaattaa gagacggaac agcctttttc
     6001 caaggtgtag ttgtaaaaag cgaagtgtcg gaagaagttt tccaaacagc taaaaatcta
     6061 caccaagaaa catccgtgtt agtaactgga gaaatccgtg aagacagtcg ttcaaaattt
     6121 ggttatgaaa tcggaattac aaatgtggaa gtggtaagcg agagccacga ttatccgatc
     6181 acaccaaaag aacacggaac agacttcttg atggatcatc gtcatttatg gctgcgttct
     6241 tcaagacaac atgcgattat gcagatcaga aatgaaatca ttcgtgcaac gtatgaattc
     6301 tttaatcaac atcattttgt caaaattgat ccgccgatct tgactggttc tgcaccagaa
     6361 ggcactacgg atctattcga aacaaattac tttgatcaaa aagcttattt atctcaaagt
     6421 ggccaattat acatggaagc tgctgctatg gctttcggaa aagtcttttc attcggtccg
     6481 actttccgtg ctgaaaaatc aaaaacacga cgtcatttga tcgaattctg gatgatcgaa
     6541 ccagaaatgg ctttcactca tcaagaagaa agtttagaag tacaggaaca atatgtagca
     6601 ttcttagtac aaaatgtttt agatcattgc gaatatgcat tagatgtact aggacgagac
     6661 aaagaagtct taaaaactta tacaaaattg ccattccctc gtattactta tgatgatgcg
     6721 atcgaattac tgaagaaaaa tggatttgat gacatcgaat ggggcgaaga ctttggttca
     6781 cctcatgaaa cgttcattgc gaattcattc gaacagcctg tctttatcct aaactatcca
     6841 aaagccatca agccattcta catgaaacca catccaacaa gagaagacgt ggtgatctgt
     6901 gcagatatga tcgcaccaga aggttacggt gaaattattg gcggaagcga acgggcaaca
     6961 gactatgatt tcttgctaga acaaatccgt aatcacggtt tggatgaaaa agaatattca
     7021 tggtatcttg atctacgtaa atacggttct gttccgcact ctggttttgg tctaggtctt
     7081 gaacgaacag tcacttggat tgctggtatc gaccatgtac gtgaagctat tccattccca
     7141 cgtttgttga accgaattta tccataagag gtgatgaaaa agctgttctg catcaagtaa
     7201 ttagaacagc caagcaaaaa cagctgttca tgtttttgaa ttggcgggac ttattaccgc
     7261 agatgtaagc ttttgaatac cgtttagtgg agaggttgtg aaaaagctgt ttagtttcga
     7321 gtattaagaa aaattttgtg gaaatggctt tccacatttt tgcataaatt tggcttaata
     7381 ccgagaaact ggcttttgaa caccgtttaa ggaagaggtt gtgcgcctgc cgttcagctc
     7441 cgagtcacaa ggagtaattt caaaaaacag tttttcatgt ttgatgacta ttgtgacttg
     7501 tgaccgagga gttggccgga gagcaccgtt tattctaaaa aagaactgcg aactctcgca
     7561 gttctttttt taaaatacgg gataaaggaa gtttccagca gacaagagaa gaaagcaaaa
     7621 gaaattgcta tttgattcac aaggttctat aacgaaatcg caatcaatca aacatttaca
     7681 aagaaggtaa ttcaaatgga aatctgattt gatgatgctt ctgctgttga aataaagcag
     7741 catctagcac ctgaaaacaa actaatagta acattcgaag atggagtagg tccgtatttt
     7801 cagcatgcaa taatccatat gtaagttcaa ttcacccttg aaatcatcgg accagataaa
     7861 gttatgacca atctatccca agcaatctag aagagatatt agtaaaggga catttactag
     7921 aagtcttaga tgagcctata aatatatgtt ctgatggcgt catcagtggt ctgattgacg
     7981 gaagcttagg tgtgatcgat ctctctggac caaacaacga aggaatcaag gggaatccgg
     8041 cacgttaaga aaaaaatagc ataaaaaact agacacttga tgagcgttca ttcaattgtt
     8101 tgaagggact aggctggtgt cattttttat acatatattt tctctttcgt cttgataggg
     8161 cttatgggat aatataagga agaaaatcat cgttttattc aaaaaggagt ttttgacaaa
     8221 tgaaaaaacg tatattattt atcggtgata gcattacaga cgcaggaaga gaccgagcag
     8281 aagcaactga tctaggtaaa ggttatccac ttttgattgc cggaaaacta atctcccaat
     8341 atccaacgat ggaatttgaa tgcatgaacc gtgggatagg aggagacaaa attgcagatc
     8401 tgcaagtacg ctggcaagaa gattgtttag ctttacaacc tgactatgta tcgattttga
     8461 tcggaatcaa tgatacctgg cataatacta gcgatcaggc tatattcgga actgagaaat
     8521 ctgctcagca atttgaatcc gtttatcgaa aattactaaa tgaacttcaa acagtgggaa
     8581 tctgcaacat catcttgatg gagccgtttg tacttcctat aaccgacgac cgtcatggct
     8641 ggcgtaaaga cttagaccct aaaatccaaa ttgttcgtaa acttgctaag gaatatggcg
     8701 cattgctggt tcctttagat ggtatattca atgctttagg gattgtttat ggtttttcga
     8761 aatatacaag agaagatggg gtccacccaa cgattggcgg acatgagatc attgcacaaa
     8821 gctggataga tgcaattgcc gcagtcgatt tttttagtgg agataaaaat gagcgaaaga
     8881 aaagtgagaa atgatggaaa tacggtgggc agtaaaagaa gatctacctc aaatcaatca
     8941 gctgattact gatcatccag aatcattcgt aaaagcaaaa acggcagctg acctaaatga
     9001 taagaataaa ctattgctcg ttgctgtaac aaaagaaaaa cggattatcg gatttgcgca
     9061 agcggacgtg caacagtcag aagaacgatt ggatcagcga ccatcaggaa aactaatcca
     9121 acacacatta gtaacaaaag aaaatacgga agaaatccaa aaaaaatttg cagaatattt
     9181 gatactggaa gctaaaaaaa gaagaataaa atcatttttt gcccagtttt aatcaaaaac
     9241 agtaatagaa ggagaaatac aatgagttgt ttaggaaatg tcatctggtt tatattcggc
     9301 ggactaatcg gtggtcttag ctggttagca gcggggatac tttggtgtat cacgatcata
     9361 ggtatcccaa tcggtatgca atgttttaag atcgcctccc tttcttttgc gccttttggc
     9421 aaagaagtaa tttatcacca gtctggcatg tcattgattg ttaatatcat ctggctgatc
     9481 gtttcaggcc taccaattgc tctcgcacat gtcgtcagcg gcatccttct atgtatcacg
     9541 atcataggga taccttttgc caagcaatct ttcaaacttg ctcgattggc gttgatgcca
     9601 ttcggtgcag aaattgtata aaagagaata ataaaggtta gataaagcat agagtcaggt
     9661 gggatacatg tatttcacct gactctatgc gttctcctgt ataagttctt ccatgtgact
     9721 tttacgtctt ttatttatat ggggttactg tttatggaaa gttgaaataa ttttcattaa
     9781 agaactcttt ctatattttt gaaagcgtag tggagcttcg aatatctggg aaggacattt
     9841 tgcagggatt gaaaaaagat attgtcctat cgaaaaatta atgaatttag acaaattgcc
     9901 agcaacaggc ttcaaactta gttgctatcc tgtcaagatc aagaaggcaa gtgcgggttg
     9961 gataagagca gtggcaatga tcgaaaagaa aaagaaagaa taagccaaaa catctgtatg
    10021 gaagaaattt tccgatgcag atgtttttca ttttttcttt cggatacctt gacatatgaa
    10081 taaccgttca tttataatta gttatgaaga gatattcata tgttgaggcg aggaggtcat
    10141 taaaatgaaa agttacagat tagaaggttt agattgtgcg aactgtgcaa tgaaaatcga
    10201 aaaaggagtt cagaagatca atggagtcaa ggaagcaacg gtaaacttca cttctggaaa
    10261 actaacgatt gacgcagagg aagatcattt ggctacgatt gaacaagaaa taaaaaaagt
    10321 agtgaaggaa ttagaaccag atgtcaaagt aacagaaata gataaggaaa aagtatctga
    10381 acatggaaat gaaaaagaga gaaatacgct gttccggatt ttattttccc ttgcaggtat
    10441 cgctttattg ctattatttg attttaatga accaattcgc ttgatagggt atttattgat
    10501 ttatctgctg ataggatatg atgtagtgaa gaaggcagtg atgaatatcg tcaaaggaaa
    10561 aatctttgat gagaattttc ttatgtctgt tgctacgatt ggcgctatgt tgatcggtga
    10621 atatccagaa gccgtagcag tgatgctatt ttatcaaatc ggcgagtatt tccaaggatt
    10681 ggcagtcagt cattcaagaa aatcgattcg cgaattgatg gcgatccgtc cagaaacagc
    10741 tcacgtgcag acgacggaag gattgatgac cgtgaaccct gaagacgtgc agatcggtca
    10801 gtttgtactt gtgaagcctg gtgaacgtgt accgttagat ggaacgatca tcgaaggaga
    10861 atcattagtc gatacgtcag cacttacagg agaatcagtc cctaaatctg tatatgttgg
    10921 tgaaacagta ttaagtggat ttatcaataa aaataaacca tttttagttc aagtagaaaa
    10981 atcttatgaa aattctacta tcagcaaatt attagaatta gtagaaaatg ccagcagtaa
    11041 aaaagcacca gctgaaaatt tcattactaa attcgcgcgc tattacacac cagtcgttgt
    11101 aggattggcc gttttattag ctgttttacc tccacttgtt gtttctggag cggcgttttc
    11161 tgaatggatc tatcgagcat tgacattttt agtgatctca tgtccatgtg cattagtgat
    11221 ctccgtaccc cttagtttct ttggcggtat cggaggagca agtaaaatcg gtgtattagt
    11281 aaaaggttca aattacttgg agttgcttgc acaaactgag acagtggtat tcgataaaac
    11341 cggcacatta acgaaaggtg acttttcgat ccagacgatc gatacaaaaa tcgatccaaa
    11401 gatattcatg caatatgttg cgagtgcaga acagttttct acacatccga ttgctcaatc
    11461 tgttttagaa ggctacgcag gtccgctttt accaacagct aatatccaag aatttgcagg
    11521 tgaagggatc ttagctgaag ttgatggcaa acaagtatta gcaggtaatc acaaattgat
    11581 ggaaagattt gaaatctctt ttccttcaag tcaagaaatc ggtacattgc tttatctagc
    11641 gatcgatcaa agttacagtg gttatcttgt tattgcagat accttgaaag aagatgccgt
    11701 agacgcattg gttcaattaa aaaaggctgg tgtgaagaac acagtcatgt tgacgggcga
    11761 ttcgaaaaaa attgctgatc atatcgggaa gcaagtaggc gtggacaaga tatatagcga
    11821 attgcttcca gaagataaag tgcagcggtt agaggaaatc ttacaaagaa acaataaaaa
    11881 gaccgcattt gtcggagatg gaatcaacga tgcaccggtg ctagcaagag cagatgtagg
    11941 aatcgcaatg ggtggattgg gaagcgatgc tgcaattgaa gcagcagatg tagtcatcat
    12001 gaatgatcaa ccatcgaaga ttgcagaagc aatccattta gcaaagaaaa cattgaaaat
    12061 cgtcaaacag aacattgtct ttgctattgg gataaaaatt ttggtacttg ccttaggtgc
    12121 ttttggtttt gcatcaatgg gagatgcagt atttgcagat gttggggtga cagtattagc
    12181 tgttttgaat gccatgcgaa gcttgcatgt aaaaaataaa cgttgatcaa tgaagaggac
    12241 gaatgaacgt cctctttttt ttatatcctt ttcttaatga aaaatgtaaa gaaaatagat
    12301 aggattataa aataactaat gtttttaatt ttgcagaaaa ttcaaaatag cttgaaattc
    12361 aataaggtaa atgaaataaa agaaaataac ttattttttt gatggaaaaa atatgaaaaa
    12421 acgatgtgta ttaaataaaa gaatacacac ataaaataac actgtcttgt aagtttgtta
    12481 aaaattgaat atgattacat ctggataaca aatttttatc ataaaggaga gaacgaatga
    12541 acaacaaaca attacgctgg tttactgttg cgttaattgc atttaacatg gtttggggca
    12601 tggggaatgt agttaataac tatgctcagc aaggagtatc agttgtcacc tcttggctat
    12661 tgattttggc catttatttt attccatacg cattgatcgt tggacaatta gggtcagcct
    12721 tcaaggatag taaaggaggc gtcagttcat gggtcgaaaa tacgacatct aataaacgac
    12781 tggcatacta tgccgcttgg acttactggg tcgtccatat tccttatttg gcacaaaagc
    12841 ctcaagcaat cctgattgct ggcggttggg cagtccaagg aaatggaaat atcgtaaata
    12901 cgatgtcagt acaaatggta gcagttattt cacttattat atttcttgcc tttttatatt
    12961 tatcaacaaa aggactttct actttgaaag tgattggcgg actggccgga acagcgatgt
    13021 tcgtcatgtc gatcttattt attcttttag ctgtaacggc accgttcatc aatccaacga
    13081 tggaatttgc cacaccacat atgaatcaag tgaaaacata tattccaaca tttgatttca
    13141 gttatttcac aaccgtttcg atgctagtat ttgcagttgg aggagcggaa aaaatatccc
    13201 cttatgtcaa ctctacaaga aatcctgcaa aggaatttcc taaagggatg atcttcttag
    13261 cagcaatggt agggatttgt gctgtattag gctcagtcgc aatgggtatg ctgtttgcta
    13321 gcgataatat tcctaaagac ttgatggcaa atggggcata cagtgctttt caaattttag
    13381 gtaattacta tggtatcggt aactcattga tgatcattta cgcattgaca aacatgattg
    13441 gacaaatctc cgcattagcc ttttcaattg atgcaccact aaaaatcttg ttagcagatg
    13501 cggatccaga atttgtacca aactggctac gtaaacgtaa tcgtaaaggt acattggtga
    13561 atggttatct tctgacaggt atactagtag gaatcattat tttgttgccg atctttggta
    13621 tcaaagatat gaatgaatta gtaaaatggt tgacgaactt gaactcagtt gtcatgccaa
    13681 tgcgttacct atgggtgttc ttggcatata tgatgttgaa taaagcttat aagaaattca
    13741 attctgaata taaatttgtt aaaaatccaa aaatcggttt tatctttggt gcttggtgct
    13801 ttgccttcac tgcgtttgca tgtatcctag gaatggtgcc aaaagtagat tatactgctg
    13861 atcctaaagc atggtggttc caattattca cgaatatcat cacaccaatt gtcttgatct
    13921 tattaggtat gatcttgcca gcaattgctc gtcgagacaa aaacaaagaa atcactgaac
    13981 cagaaacagt ggttcagcct taaaatagaa atacttgtta caagaggttg tgacagaagt
    14041 ggtcagcttc aagaaataag aaggaattta cgaaaattgc ttctcaaatt tttgtgaagt
    14101 ttcggcttgt ttttcgcaga agctacttct ggaacaccgt gaatcagagg ttgtgaaaaa
    14161 gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agcccctcat atttttcgtt
    14221 ttgctgggct tattaccgca gatgcaagct tttgaacacc gtttaagaaa gaggtagtga
    14281 gcctgccgtt taactccgag tcacaaggag caatttcaaa aaacaacttc tcatgtttgt
    14341 tgactattgt gccttgtgac cgaggtgttg gcaggagaac accgtttaag gaagaggttg
    14401 taaaatcagc gatttgacct gagtattaga ggaacaaacg aaaaaatagc tcctcatatt
    14461 ttgccgtttt ttgagttaat gctgaaggtc agctgattga acaccattta ttcgaaacaa
    14521 gggactttga cacgactttt gtcacagtcc cttgtttttt tgcggcgtta taagtggtat
    14581 gatcgaacca aattccaaag agaagtgagg gagaagaatg aagatcatcg tgattggaca
    14641 aagtgggtcg ggaaaatcga ccctcgcaag gaagatcaaa gaaatcaccg actttccgct
    14701 actgccgcta gaccttttat ggcatacaac agactacagt attcaggcaa aaaagtggtt
    14761 tttgcaagaa cagcaatcgt ttatggtatc taatccgtca tggattgttg aaggaaatta
    14821 tacttctaca ttagaggaaa ggattaaaga agcagataag atcatttggc ttaaagtgcc
    14881 gcgttatctc gccatctacc gagtagtttg gcgttctcta aaaagaaaga taaacaaaaa
    14941 atctcggcca gatatgcctg aatcattttc agagaaacta aacagggaat acttagaatt
    15001 tttatctttt atctggcatt ttgaagaaaa caatgaaccg aaaatacagc agctgatcca
    15061 agtagctaat gcaagaaata aactgatcat ccttaaaaca agacgagaga aacaagaatt
    15121 tttaactaaa ttgaaaatag agagcaaaaa taattgacag tttttgttta caagcgtaat
    15181 ctgtattcat aagctaatga ttacatttgt aaacgaaagg tgtgaaataa atggaaaaag
    15241 tcaaaacgcc agtaaagatc agtgattcag agtgggagat catgcgtgtt atttggacac
    15301 ttggacagac gacagcccaa gaaatcacgc agatcttagc tgattcgatg gattggaaac
    15361 cagcaacgat caaaactttg ctgggacgtt tggtaaaaaa agaagtgatc tggacagaac
    15421 aagaaggaaa aaaattcatt tatcatccag ctgtctcgga gatggaaaca gttcgcagtg
    15481 cgacggaaaa tcttttttcc catatctgtg caaaaaggat tggagagacg attgcggatc
    15541 tagtagaaga agccactttg actcaagaag atatcaatga gattttgaaa caactggaac
    15601 aaaagcaacc agtagatacg atcgaatgta actgtatccc aggtcaatgt gaatgtaaac
    15661 aacatcaata ggaggaagaa aaaatgaaac aacaattttc aatcgaaggt atgagctgca
    15721 atcattgtgc agcaagagta gaagaaacag taagcgcact ttacggcgtg caaaaagtga
    15781 aagtaaattt gaaaaaagca aacggtacgg tcaagtttga tgaaacaaaa gttcaatccg
    15841 aaaagatttg tcaagcaatc aatggattgg gttataaagc agaggtgatt tgatggcaac
    15901 agcagaaacc aaaatggata cgttcgtcat tacaggtatg acttgtgcaa attgttctgc
    15961 taggatcgaa aaagagctga acggacaacc tggtgtggtc aatgccacag tcaacttggc
    16021 cactgaaaaa gcaagtgtca aatatgaagg gacgaccact gaaaaattaa tccaaagcgt
    16081 agaaaacatc ggttatggtg caattttgta cgatgaagcc cacaaacaaa aaattgcaga
    16141 agaaaagcaa gcgtatttga aaaaaatgct attcgatctt atattgagta cggttttgac
    16201 tttgccgttg atgttgtcaa tgattgctat gatgttagga agccatgcgg cgattgttca
    16261 cttttttcat tttccaatcg tccagttagt gctgtctgct cctgtccaat tttatgtcgg
    16321 tgctcgtttt tataaaggtg cgtaccatgc aatcaagacg aaagcaccaa atatggatgt
    16381 attggtagca attggaacat cggctgcctt tgcattgagc atttacaacg gatttttccg
    16441 tggacacccc caagatcttt attttgaaag cagcagtatg atcatcacgc tgattttgct
    16501 cggcaaatat ttggaacata cagcaaaaac gaaaacaggt aatgcaatca aacaattgat
    16561 gtctcttcaa acaaaaaccg cccaagtgat aagaaacggg aaagaagaaa cgttagcgat
    16621 tgaagaagta gtcgttggtg atcaactagt catccgtcct ggtgagcaga ttccagcaga
    16681 tggtcgaatt atttcaggaa gcagtgcgat agatgaaagt atgcttactg gtgaaaatct
    16741 tcctgtagaa aagaatccgg atgacacgct ttttggcggg acaatcaata cgaatggtct
    16801 gctacacatg gaagtcacac aagtcggcaa gcagacagta ttagcgcaaa tcattcaaat
    16861 ggtggaagat gctcaaggga gcaaagcccc aatccaaaaa atcgcagatc ggatctcagg
    16921 gatttttgtt ccgatcgtat tagtcatcgc gtttatcacg ctcatagcta caggtttgat
    16981 cactggtgat tggcaactcg cattgatcca tagtgtctct gtattagtca ttgcgtgtcc
    17041 atgtgcatta ggtttagcga ccccaacagc tattatggta ggaacgggtg ttggtgcacg
    17101 aaatggaatt ttaattaaag gcggagaagc attagaagca gctgctcact tagacagcat
    17161 tgttttggat aaaactggaa cgattacaga aggaaagccc aaagttacag atctagtcgg
    17221 ttcaaaagaa gtcctatcta ttttttatac tttagaacaa gcttctgaac atccactagg
    17281 taaagcaatc gtggaatacg gaaaactgca agaagcagca acatacgata tgattgattt
    17341 tacagcccac ccaggtgctg ggatcagcgg tacgattaat ggagtacgct attttgcggg
    17401 tacacgtaaa cgattaattg aattgaacct atcatttgat gaataccaag aacacgcgtt
    17461 agaattagaa cagcagggaa aaacagtcat gtttttagct gatgaaaagc aagtgatcgg
    17521 gtggattgcc gtggctgatc aaatcaaact agaagccaaa caagcaatca agcagctcca
    17581 gaataaagga ttagatgttt ttatgctgac aggagacaac aaactggcag ccgaaacgat
    17641 tggtaaacaa gttggtattg atccaaagca tatctttgct gaagtacttc cagaggataa
    17701 agcagcctac gtagaaaaac ttcagaaaga tggcaaaaaa gtcggtatgg caggcgatgg
    17761 aatcaatgat gcaccggcct tagcattagc tgatgtcggt atggcaatgg gaagtggaac
    17821 ggacattgcg atggaaacag ccgatgtgac gctgatgaat agcagtttgg catccattgc
    17881 acaaacaatc gagttgtcta ggttgacatt gagaaaaatc aaacaaaatc ttttctgggc
    17941 ttttgtctat aatacgattg gtattccttt tgccgcacta ggctttttga atccaatcat
    18001 tgcaggagga gcgatggcgt ttagttccgt cagtgtattg ttgaactccc tgagcttaaa
    18061 tcgacacatg aaaaagtaag agaagggatg gagtaaaaat gaatgggaac gatatggaga
    18121 aaaaacatga gcataaaaaa gaagtagtaa acaaagaaag tacagaatct catgaaaaac
    18181 agatggagat gaaacatgac catagtcaga tggatcattc catgcacatg ggacataacc
    18241 atggagatat agcaaacagc aaacaaatgg accattcgat gcacatggat cacgaacacg
    18301 gcggcatgga tcattccatg cacatgggga atttcaaaca aaaattttgg ctatcgctta
    18361 tcctagctat cccaatcatt cttttttcac caatgatggg aatggaattt ccatttcaag
    18421 taacgtttcc tggttctgat tggctcgtat tgatcttagc aactatacta tttatctatg
    18481 gcggtcagcc atttttaagt ggagctaaga tggaattgaa acaaaaaagt cctgctatga
    18541 tgacactgat cgcgatgggg attacagttg catatattta tagtgtctat tcgtttatcg
    18601 caaatctgct caatccacat acacacgtca tggatttctt ctgggaattg gctactttga
    18661 tcgttattat gctactaggt cactggattg aaatgaatgc tgtgtcgaat gccagcaatg
    18721 ctttacaaaa actagcagaa ttactgccag aatcagtgaa acgcttgacg aaagatggaa
    18781 aagaagagac agtttcattg aaagaagtaa acgaaggtga tcgtttgatc gtccggtctg
    18841 gtgataaaat gccaacagat ggtgtaatct tgaaaggtga aacaattgtt gacgaatcag
    18901 ctgtgactgg cgaatcaaga ggaatcaaaa aacaagccaa tgacaaagtg attggcggtt
    18961 ctatcaatgg ggatggaacg atcgaaatcg aagtaactgg aactggtgaa aatggttatc
    19021 tagcgaaggt tatggaaatg gtgcgaaaag cacaaggaga aaaatccaag ctagagtcat
    19081 tatctgacaa agtggcaaaa tggctgtttt atgtcgcatt aattgtgggt atcctggcat
    19141 tcatcgcctg gttgttcttg acagatcttc ctaatgcatt agaacgtatg gtaacagtct
    19201 ttatcatcgc ctgtcctcat gctctaggtt tagctatccc attagttgtt gctcgctcca
    19261 catcaatagc agctaaaaac ggattacttt tgaaaaaccg caatgcactg gagcaagcca
    19321 atgatctaga tgtgatcatg ctggacaaaa caggaacact aacagaagga aaatttactg
    19381 taacgggtgt cgaagtactt gatgatgcgt tcaataaaaa tgaaatcctt caatatctag
    19441 gagccttgga agcgaatgcc aatcatccat tggctgttgg cattatgaat tatttgaaag
    19501 aacatgaaat caagccttat caagctgaaa atctaaaaaa tctttcagga gtcgggctag
    19561 aggcaacagt caaaaaacaa caagtgaaaa tagttaatga aaaagaagtt gagcgtctcg
    19621 gattaaacgt agaacaagca ttattgaaac cttaccaaga acaaggaaat accatcagct
    19681 tcctgatttt agaaaatcat ctagctgcaa tcgttgcttt aggtgacgta gtaaaaacag
    19741 aagcaaaaga atttatccga acattgaaag aaagaaaaat cactcctgtc atgcttactg
    19801 gtgacaataa aaacgctgcc caagcagtag cagattattt agggatcgaa gaatattatg
    19861 gcggtttatt accagatgat aaagaagctg ttgtccagaa ataccttgac caagggaaaa
    19921 aagtaatcat ggtgggtgat gggatcaatg atgcgccaag tttagcccgt gcttcaatcg
    19981 ggatggcaat cggtgcaggg acagatatcg caatcgattc tgcggatgtc gtattgacaa
    20041 acagcgatcc aaaagatatt ttgcattttc ttgatctagc caagcaaacg cgaaagaaaa
    20101 tgatccagaa cctctggtgg ggggcaggtt acaatattct tgcaattccg ctagcagccg
    20161 gaattcttgc gccaattggt atcatattaa gtccagcagt tggtgctgtc ttgatgtcgt
    20221 taagtacggt agttgtagct ctaaatgctt tgacattgaa aatcaaataa taatgaaaaa
    20281 a
//
LOCUS       DARPZJ010000045        20181 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.047, whole genome shotgun sequence.
ACCESSION   DARPZJ010000045 DARPZJ010000000
VERSION     DARPZJ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.047"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="SLE23_001999"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="SLE23_001999"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEI8468885.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="SLE23_002000"
     CDS             1011..2258
                     /locus_tag="SLE23_002000"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEI8468886.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="SLE23_002001"
     CDS             2334..2678
                     /locus_tag="SLE23_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468887.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="SLE23_002002"
     CDS             complement(2795..3121)
                     /locus_tag="SLE23_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468888.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4696)
                     /locus_tag="SLE23_002003"
     CDS             complement(3494..4696)
                     /locus_tag="SLE23_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8468889.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4813..5328
                     /locus_tag="SLE23_002004"
     CDS             4813..5328
                     /locus_tag="SLE23_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8468890.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5527..5973)
                     /locus_tag="SLE23_002005"
     CDS             complement(5527..5973)
                     /locus_tag="SLE23_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEI8468891.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="SLE23_002006"
     CDS             complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="SLE23_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEI8468892.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7852..8481)
                     /locus_tag="SLE23_002007"
     CDS             complement(7852..8481)
                     /locus_tag="SLE23_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEI8468893.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8465..8929)
                     /locus_tag="SLE23_002008"
     CDS             complement(8465..8929)
                     /locus_tag="SLE23_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8468894.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9416..10684)
                     /locus_tag="SLE23_002009"
     CDS             complement(9416..10684)
                     /locus_tag="SLE23_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEI8468895.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10915..11652)
                     /locus_tag="SLE23_002010"
     CDS             complement(10915..11652)
                     /locus_tag="SLE23_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8468896.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11719..12288)
                     /locus_tag="SLE23_002011"
     CDS             complement(11719..12288)
                     /locus_tag="SLE23_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEI8468897.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12416..13288
                     /locus_tag="SLE23_002012"
     CDS             12416..13288
                     /locus_tag="SLE23_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8468898.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13630..14502
                     /locus_tag="SLE23_002013"
     CDS             13630..14502
                     /locus_tag="SLE23_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8468899.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14499..16457
                     /locus_tag="SLE23_002014"
     CDS             14499..16457
                     /locus_tag="SLE23_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8468900.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16708..17559)
                     /locus_tag="SLE23_002015"
     CDS             complement(16708..17559)
                     /locus_tag="SLE23_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8468901.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17682..18149
                     /locus_tag="SLE23_002016"
     CDS             17682..18149
                     /locus_tag="SLE23_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEI8468902.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18412..18894)
                     /locus_tag="SLE23_002017"
     CDS             complement(18412..18894)
                     /locus_tag="SLE23_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEI8468903.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18994..19857)
                     /locus_tag="SLE23_002018"
     CDS             complement(18994..19857)
                     /locus_tag="SLE23_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEI8468904.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6066 a         4155 c         3664 g         6296 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gtttttttca
     4441 aaccgatccg actagataag aaacctgtaa atagcatcac cacaccagtg actaacatgt
     4501 aactagtaaa taacagggtc gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt
     4561 ttaagattgg gtctactaga cccactccca taaaagcgat catacaggta gctgctacaa
     4621 ctagcgctga acttttcccc tttgtttctt catttgtttg ttcttgtata tctatttgat
     4681 tctccaatat ttccatccct ttctctctat tagcatcata catgatttat tttacatgta
     4741 aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata ataaagaaaa taagacgaga
     4801 ggtaggattt ttatgaatac tttagcctat atattattat gcgtgctttt atccaaacca
     4861 cgttctgggt atgaattgaa gcagctgatc acaatttttt gggaagccca tcacagtcag
     4921 atctatacaa cgcttgccaa gttagaccag cagggttatg tgaccgtttt ggacaaagac
     4981 gagcactctc aaaaaaagat ctaccacttg actgatgaag gacgtgctct tgtagaggaa
     5041 tggatcaaag aggaaactcc cgctcctacg caaaaagatg aatttctagc aaaaatctat
     5101 gctttttcga cgctcgataa aacaacagct actggactgc tattcactag agaacaacag
     5161 ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg acctctcgct agacaagaaa
     5221 caagaatttg gacgttatgt tgtgatccag cgcagaatta tgctttgtca gcaggaactc
     5281 caatggtgtc agcaagtaag agaacaaatg cagcagtttt ttgagtaagg gataaacaga
     5341 acctttctag aaatatctat tgaagagcaa attatcttca ataaaagagc aatacagttg
     5401 gaaaagaaaa agcgatccga acgacaggcc aaaacctatc gttcggatca ctatttttct
     5461 agaactgcat tcaagagact atgacaaaaa gcatgccaag gccttttttc aaataacagt
     5521 gttccatcat tcattacttt gaattgcttt tagcacactt cttgaaagcg ggccaacgat
     5581 gatcaactgc aacggtaaag cggcaatcac attcattttc caagcattca tataagcaga
     5641 gaataattga tcaggtattc cttgttccat gatcacaccg aataaagaca tacatgtcac
     5701 cattcctaaa accatcaagc atgaaatagt taagatcatt tggaccttgc tttctggatt
     5761 tactggtagt ttaaaggcaa tttttttcgc cagcacaccg atgatgaaga catccaaaat
     5821 gaaagccacc acgaatccag gcactagacc aatcaacaaa cttgataaat gaagatcttg
     5881 atgcagccat aaattatacg cgctcatccc caagaccatc aaaaaacaca tcattgttgt
     5941 aaaaattatt ccttcttttt tatttgtagg caatctgtac cactccttta aatttgtcac
     6001 gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac tttttttatt ttctgccctt
     6061 ttatttcata aacttcatca gccgtacgct cgacaaagta agaatcatga gaagtaaaca
     6121 aaatcgttcc cggatatatt tgcattagct tctctaaagc ttcgatcgtt gccatatcaa
     6181 taaaattagt cggttcatct aacagcaaca cattacttgg cttagtaaaa agcaaagcaa
     6241 tcgtcagacg ggtcgcttct cccccactta atgtacataa cggtttcgtc aaagtttcct
     6301 gagcaaaccc taagtgattc agcaaactac ggacaagcga ttctgaaaac tctgtttgtc
     6361 tcatgacaaa acgaatgatg gattcttcag atgtcatttg ataacccttt tgctgatata
     6421 cttgaaagct tactttcgga gagagaagga ttccttctcc ttgtttgcgg atatgttcta
     6481 ataaggttgt cttacctgaa ccattttcac cgacaatcgc gattttttta cctaaagaaa
     6541 actgaaaatc accatttacc agtaatgttc tcccacttct ttccaattgg acattttgtc
     6601 ccatgatggg atagcggctg tggagttcaa gagattttgg tactggaaaa cggatttgtt
     6661 tcatctgctg cggcttggtt gtttctccta ttttttggag tcttctctct aatgttttcg
     6721 cattcttttg gatggctttt tgtacactgt ctttttgttt agaggaagac aaccgatccg
     6781 gtctgatttg ttgctttttc tttttactgg acactttttc caacttttcc gcttgttttt
     6841 tcttttcttg gatcgatttt tccaatcgtt ttttctcttt catgatcgac tctgcttctc
     6901 gtagctgagt ctttttctcc aattcctttt gagtgagata ggcactataa ttccccgaaa
     6961 actctcggat ttctccgtct tttacttccc agattttcga tgctagctca tctagaaaat
     7021 agcgatcatg actaacaaaa accagcgtac cataataata acgaagctct tcaatcagtc
     7081 gatcaatact ttttctatct agatgggttg ttggctcgtc tagaagcatc ccttgttcat
     7141 aagaagaaag aagacgtatc aactcgatct ttcgttcttc ccctccgctc catttccgct
     7201 ctgaagtttc ttccagtctt aactggaaat gactggctaa ttccaaattt aggtcctttg
     7261 cttcagcgag ataggttaat tgaggcaggt agttgaaggt gatctctgtt tggattttcc
     7321 catgatcggg aaaaagttca ccggctatta gtttgagcaa agtcgattta ccgacaccat
     7381 tttctcctat gatccctata cgatcttgct gatagacacg aagagaatca atagatagtt
     7441 ctagctggtt gccaaagctg acttgtagat ttgttatatt tactgctaaa ttttccatat
     7501 gttttacact cctatttcat gtaaaacaac aattatcgat actaaaaaag agcagaaaaa
     7561 tctgtttgca aaaaaactgc atcacatctt ttcctactct gaacgaaata actatgacta
     7621 aatcaccaaa tctgtcatag ctttcaccta ttctactgtc gttcgaaaaa atggacatac
     7681 tccatccatg aaattgttgt ttatacatgt cttttgaatt tatttagttg ttattcaaaa
     7741 gttcgaaacg taatttcatc gatgcagtca tttttccgac ctcctttttt attaggttac
     7801 cacacacgat tcaaaaaaag caatagctac tgaatagtaa ctgaaaacct tttattcgaa
     7861 cgtagtgatc ttttctggtg ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc
     7921 tattgataaa ataataactg gaacataacg gtctttatcc aaaccaaatg cctctgccaa
     7981 ctgatctgct tcgaatccac caattggatt tgtttcatag ccatgatcac gcgcaactaa
     8041 catgaattgc atagccgcta agctagaatc gactttgact acatcgttca tttcttctct
     8101 tgaaaaactc ttgtaataag gaatgatcgc agctaattgt tgatctctga cttcttttgg
     8161 catcttccct gattcgtaag cttggttata gatttcttcg ccatattcgt aacattgcat
     8221 atcgccaaaa atcatgacca ttgcagaaga agtatcattt tgtctcgtat tgaaacggat
     8281 caaaggacgc aagatttctt ttgcttcctc gctttcagcg accacaaagc gccatggttg
     8341 catattgaca gaagaaggtg cagtcgtcgc ttctttgatc atttccagca tttcttcgtg
     8401 tgggattttg tatgtttcat catatacgcg aacggatctt ctaccagtca taattgttga
     8461 aaaatcattt ttttgttcca ttattattaa cctctttcgt ttctgttgtt atattgcaaa
     8521 gttgggtatt caatttatct aaaagtgtta gaaattgttt catttctaca tcgctgaaag
     8581 ccggggatag cacggaacct gtatctttat ggtccatttc acaatgctcg attttcttct
     8641 gggctttttc tgttagcgct acatacactt cccggttgtt ctgaggattt ctctgacgcg
     8701 aaacatagcc atttgcttcc aataccttca gatgacgagt aactgctcct tgatcaatct
     8761 gcaacttttc ttgcaaactg ctttgtagca atggattttc ttctttcagt ctcatcatga
     8821 tctcgtatct agtaagactt ataccgatat tttcttcaaa gatctggacg attttttgat
     8881 cggctaattt gatttgatat aaaaggtgac taatctcttc taaagacata atttcctcct
     8941 ttctaataat tgactcgtca acgattgact tgtcaataat agaataaaaa aagaaaaaag
     9001 tcaaagaatc agctgtgtaa taaaaaaaac gctctcaata gaaaagtata gagaaaagaa
     9061 attttttgta gaatgaacgg aaaaaatgat aaagaaagca caacgctaaa accaagatta
     9121 ttgattctta tcaaactata gaagatagct cttctgcagt agaaaatttt acaccgccaa
     9181 aaatttccga aatcgccttt tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg
     9241 cttaaacagt aataaaaaag ttatgacaag atgttgtcac aacctttttt gagtaaacgg
     9301 tgttcaaaaa cttgcatctg cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt
     9361 ttttgtttgg ctgttcttac tacttgatgc agggcagctt tttcactacc tctttttaat
     9421 aaccataaaa tcctattcct tcatatctcc agcccatcgg tgttagccaa tctctttcct
     9481 tagcactcaa ggtatagtga tgggtaccag ttttttcatt tggattaaat agtcgataaa
     9541 ttggcttgga accaccagaa taaaaactta gaccttcata acgccaaccg atttttgtta
     9601 aagagttgat ctcagattgt gccattgtgt aatgatggtc tccactgtaa ggattgtata
     9661 aacggtagac aggttgtccg ctgtttggtg cttgccaagc aatcccttca tattcccagc
     9721 ctacagttgg cagataattt ttttctccgg cattcaatgt atataaatgt tctcctgtat
     9781 gacggttata cagacgatac atcggagaag ttgaagttgg tgctgtatca tactgtgtca
     9841 gattataggt ttcgattaca ttgttcaatg tagaaccata attaggcgca gtggcataac
     9901 gacctgttag ccaagccgta gcatctttgt aagagttcgt attgcttttc catgcaccgg
     9961 aatagtagta aacgcctggc tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca
    10021 atgattcttt gtacgaagga tattttctaa aagcggcatt caccgtaatc cattgcccat
    10081 tcacatattc cgaagtaggc atcgtaacag attggccatt atagcttcct ttaatcccaa
    10141 atagattgta attaggggca gaagccaaag tactgttccc ccagccactt tcaacgatgg
    10201 cttgagcaat catgactgat gcatataagt cattggcact tgccaaactt tgtgcagttg
    10261 aggcaatact atcaatgaac gcttgttgag aattagcaga tgagcgagca taaaaagcat
    10321 agccagtata gttttcgaat tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc
    10381 catctgtcaa ttggttcgtg atttcttctg cattctctgg attgttctga gcttctgctg
    10441 atgtactgtc ttcggtttgt gtttgttctg ttgtttcagt tgttggttct tcggttgaaa
    10501 ttgtattttc tgagacagta gctgactgca aagtactctc tgtatcgttt tcaattcctg
    10561 tttctgaaga actcgatgtc tgagttgcga cagtttctgt cgattcttca gctagcactg
    10621 ttgtgttggc aactgctaga tttcctaaaa gaataacgct aaataataaa ttctttgctt
    10681 tcatcttttt tctcctttga attatgaaac ttttcctaaa taacagtgta actaaaaaag
    10741 taaaagcaag tcaatgtcca tatttaaata acatttgttt ctttttgatg aatttgcttt
    10801 ttctacataa aaagacgtaa atgaagaata ttcttctcca ttcacgcctt aaattgatgg
    10861 tcgtttgaat aactatttaa caagtaattc tctttggata ttatccgtta tggattatac
    10921 ttcctgtgtc gtcggacgga taatcatgtt actgacagac atccggtctg gcgtttctat
    10981 cgcaaatgct acagcagaag ctatatcttc ggaggtcaat ccccattctt tttgcgcttc
    11041 atgaagttca agagcagcct ttttgtcgct gatggtttga tataattcag tttgaacagc
    11101 tcctggagag atgatcgtag atttgatgtt attttgccgt tgctcttgac gtaatccttc
    11161 catgattgca cggacagcaa attttgttcc gcaataaacg gcggaatcag gataaacaac
    11221 atgtcccgcc acagaatcag ttgaaatgat atgcccagat ttttgttttt ccatgattgg
    11281 aagtacggcg gaaattccat ttaacacacc catgatgttg atatcaagca tattttgcca
    11341 ttcatcacgg tgaccttcaa ctaatggagc ggttggcatg attcctgcat tattgtacaa
    11401 tacatcgatt cgaccgaact tttccatcgc taaatcgata actgcttgga cttgtgcaaa
    11461 atctcttaca tctgctgttt gaatatatag ctcagcttct ggtaaagatt cttttattgc
    11521 ttttaggcga tcttctcggc gtgcagctat aactagttta gccccttttt ctgctaatag
    11581 cttcgttgtt gcttcaccga ttccgcttga agcgcccatg atgacaatca ctttttctga
    11641 taaatcattc attctattct cctcctgttt tgaaaaatct cttgcttata ctcactatct
    11701 cttatttcat cttactgttc aaataatccg ttcgacaggt ttgacgattt tggcagggat
    11761 tcctgcaacg atggtattgt ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat
    11821 ggcattctcg ccaatcgtta cgcctggcag aatagttgct cctgctccga tccaagcatt
    11881 tttcttgatg tggattggct ttactgacaa gcctcttcgt tcttttggat cggttagatg
    11941 gttcaccgtg atgaggttga cacgaggacc aatcaatact gaatcttcta aacagatgcc
    12001 acctaagtca acgaacatca cttgacgatt gataaagaca tttttcccta tactaatatg
    12061 tttgccgaaa tctgtataaa aaggcagcag aacagtcacc gtatcatcta ctttgtcact
    12121 aatgatattt tctagccgtt tgcggatatc tgctggttca tggtacccag tattcagcgc
    12181 tgctaaaggc tcttcgtttt cagcttggat ctgatggatc acttcaaaga gcggatccgt
    12241 tactcgaatc tctttattga cgatttgttt ttcgatgagg cttgtcattt tgctccctcc
    12301 ttttatcctt actttataac ggacggctta tcatgtctaa tacttataaa acatacttaa
    12361 ctattccttt taactatact tagtggtatg cttttttaaa aacaggaggg aaaaaatgga
    12421 tattcgtata ctgacgtatt ttttagcagt agctagagaa aaaaatatca gccgagcagc
    12481 aaaatctctg catatcacgc aacctactct ctcaaaacaa ctgaaagatt tagaagaaga
    12541 acttggtgtg acacttttca ctcggggctc ccgagagata cagttgacgg attctggtcg
    12601 atatctttat tcaaaaggaa aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt
    12661 aacaaatgac gcaatcatct ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat
    12721 ctctttcatt tctgatagcc ttcattcgtt gatcaaggcg catcctgata tccagtttca
    12781 tttatatagc gggaatgcag atgatatcat agacaaactg gatagcggat tacttgattt
    12841 tggactcgta atcgaaccga caaacaaaca aaaataccag tcatttcgac tgccagccca
    12901 agatcgttgg ggacttttga tacatcgaaa tcatccttta gcaaagcaaa ccgtcatcca
    12961 tccgcaggaa ctgaaaactg ttcctttgat catttcccgg caaacgtcag tggacagtca
    13021 actagctgaa tggctaggtt tcagcataga tcagttatcg atcgtcggaa catataactt
    13081 attgtacaat gcttctttga tggtcgataa cgggactttt ggtgcattag ctctagatgg
    13141 gatcatcaat acttatggga cggaaaaaat attcatccca ctcgatccgc cattacaagc
    13201 ttcactgaat ctcatttgga aaaaagacca gcctctttct cctgctgctc gtaaattttt
    13261 agatgtccta acggagaaat acagttaagt agagtttttt tccttcgctt tcagcttttt
    13321 aacaacgaat aagataagca aaagatccaa cgattaaata acataagttt cttaatttat
    13381 ttcttccttt tatttctgat aattccagta aattactata attataaaaa aagaattgac
    13441 aaaacataac tgtctatata aaattgatta cgttaacaat aattcgtttc atgtgactag
    13501 atcatactag gcatgaaaaa tctctgagga acatggtttc cctaggaggt ttttcgtgtc
    13561 tatttttgtt tggccgcaat caactggtct agcaaacgtg aaaaccaaat cttcaaaaag
    13621 ggtgcgcgca tgaaaatcaa aaagatcttt aatcaaaatg cagtattggt agatgacggt
    13681 ggacaggaaa aagtagctat tggaaaaggg attggatttg acagaaaaag aaatgatttg
    13741 atttttgatc gtgatgtcga acggatattt gtcatggaac cagaaggtca aatcaagttg
    13801 caaaatttac ttaatcagat tgatgaacgc tttttatttg cagcagaaac gatcattgat
    13861 catgcggaaa ctgttttgat ggaaaagttg aatgaacatg tattgatcgc tttgaccgac
    13921 cacattgctt tttctgcgga gaacattaat aacggtatcg tcatccgcaa caaactttta
    13981 agagaaatcg aagtgcttta cagtgatgaa ttcagtattg ctcaatgggc agtagagtat
    14041 ctgacaaaag agcttgggat tccatatact tatgacgaag caggatatat cgcaatccat
    14101 attcacagcg gacgaagcgg tcggaacaat aaccatcgca gtatccgtga agtgacgatt
    14161 gtatctgaca tcatccattt agtggaatca gaattggaaa cagatatcca ttcagaacca
    14221 ttttcactga attattcaag actggtgaat catttacgac tacttctaca acgaacccat
    14281 gcgcaacaat atgctgtttt agacacggaa atcgtagaaa tggtcaaacg aaaataccca
    14341 gaaagctata agatttctaa aaaaatccgt gtgttgctga ccaaagaata ccagctcgcg
    14401 atcacgaaag aagaactggg ttacttggcc atccatatcg agcgtttaag aagcgcaatc
    14461 gtacaaacaa atgttaacaa tcatgaggag gaaaaaaatt gaaagcatat ctacaacgaa
    14521 tgggacgttc ccttcaactt ccagttgcgg tcttacctgc tgctgcttta ctagtaggga
    14581 tcggaaactg gtgggcatct tatagtaacg acattgtcgc tcatttttta caagctggcg
    14641 gtaacgcagt tttaggtcaa ttacctttgc tgtttgccgt tgggttagca ctagggatgt
    14701 cagtggacaa atcaggtgct gctgccttgg caggtttggt cgcatttgaa gttccagtaa
    14761 atgttttaaa aactgattca gtagctactt tattgaatat caaaccagaa tcagttgatc
    14821 catcttttgc tcagatcagt aacgtattta ttggtattat tgccggattg attgcggcag
    14881 ctctttataa tcgtttccac gaagcaaaat taccgatggc tttatctttc tttagcggca
    14941 agcgtctagt gccaatcttg gctgcctttg tcatgttgct gatcagtgca gtgctactgc
    15001 tcgtatggcc tccggtttac tctgctttag tttcttttgc taaattcatt ttgagtttag
    15061 gctggggtgg tgcaggtctt tatggcttct tcaaccgttt actgatccct acaggattgc
    15121 atcaagcaat gaactccgtg ttctggtttg acgtagcagg aatcaatgat attggtaaat
    15181 ttttggcttc tgaaggaaca aaaggcgtaa caggaatgta tcaagctgga tttttcccaa
    15241 tcatgatgtt cgggcttcca gcaggagcat atgctattta cagaaatgca cgtccagaaa
    15301 acaaagcaaa aacagcttcc ttgatgctag cagcagcttt tgcttcattc tttactggtg
    15361 tgacagaacc acttgaattt tcatttatgt tcgttgcttg gccattatat gtcttgcatg
    15421 caattttcac tgggatttct ttagcagtga gtgcattctt ccattggaca gcaggatttg
    15481 cctttagtgc cggatttgtc gattacttcc tatctttgaa aaatccgatt gcgaatcagc
    15541 cattgatgtt gatcgtccaa ggattagtaa cagcagtgat ttactacttt ggctttaact
    15601 ttgctatcaa aaaattccat ctgatgactc ctggccgcga ggaagcagat ctttcagatg
    15661 acgatactgc aacgactaat tcagacaata aatatgcggc acaagcaagc aaaatctacg
    15721 ctgcattagg cggagccgac aatgtaactt cgatcgataa ctgtactaca cgccttcgtt
    15781 tgcaagtcaa agatacaggc ctgatcgatc aaaataaaat caaagccact ggcgtacctg
    15841 gtatgaagat catcgacgga aaaaatgcgc aagtcatcgt aggtacagaa gtacaattcg
    15901 ttgcagatga gatggcaaaa ctacatggtg gtgctgcagc acgacctgca caaacaaaca
    15961 ccgtggttaa aacagaaaca tttgccggtg aaacgatcga acaagatatt tacgctatcg
    16021 caaatgggaa actgattcca atcactgaag tttcagatga tgtattcgcg gaaaaaatga
    16081 tgggtgacgg ctatgctgta ttaccagaaa atggagaaat cttctctcca atcgctggta
    16141 cgatcacaaa cattttccca acgaaacatg ctgtcggaat ccaaacagat gctggtatcg
    16201 aagtcttgct tcatatgggc atcaacactg ttgacttaaa aggcgaacca ttcactttat
    16261 atgtagaaga aggtcaaaaa gtcgcaagag gtcaattgat tgctttagtt gatcttgccg
    16321 ctattcaatc tgcaggcaaa aacacggata tggtcgttgt attcacaaat ggcgacaaag
    16381 tccaaagctt agaaatcgaa cccgcacgtg atgtaaaagc aaatgataaa atcggctctg
    16441 tttccaacaa agcctgagcc atcgtcttcc ccagactttt ttatcgataa acaaacagga
    16501 gctgagacaa aaatcttgtc tcagctcctt tttccgaata aaaacggcgt tctcctgcca
    16561 actccgcggt aataagtcca gctaaacgaa acatatgaag agctattttt tatttgactc
    16621 ttcttattac ttgatgcaga acagcttttt cacaaaattt ttcttcatac tcaaaactaa
    16681 tcggcttttt cacaacctct ttatacatta ttcctgatcc aatatttctt ttaatgctgc
    16741 ttcaagagaa gttaatggtt ttcccaatac tttttctaaa tcatcagagg aaatagctaa
    16801 ctgatccttt ttaatatcat gttggatcgc taaaaacatg tcagctgctt cttgagggaa
    16861 tccggcttct tttagatttt cgacaaacgc tgcatcactt gcttcaataa tttctaactc
    16921 tttacctgtc gcacgctcta atgccttggc taattcttca tagtcagtta gattgccgga
    16981 taattctaag atttctggag agtcactttc tactagtact tttgctgcag cttctgcata
    17041 ttcacgtttc aatgcccaac ctgtttttcc atttcctgca gcataaacga attgaccagt
    17101 ttttaaagcc tgcccaatga taggtaattc attctctaca taccaattat tccgtaaaaa
    17161 tgtatgggaa atacctgaat ccttaatcat tttttcagtg aattggtgat ctggcgctaa
    17221 tacactgatc gagtgatcgg catctgcaaa acttgtataa gcgatataag ataccccagc
    17281 tgcttgtgct gccttcacta cattcttatg ttcggcttga cgatttcctg gaacgccaga
    17341 gacaaaaagc aatcgatcta ttcctttcaa cgcttctttc attgagtcta aatcatcata
    17401 atcaccaata cgtatattaa atccagcttc tttcagtgct tctccttttt cttcactacg
    17461 tactagtaca tagatttcat tttgtggaac catctttttt aagaattcca gcgcataacc
    17521 accaaaacct ccagttgctc ctgttactaa ataatgcata tttgccactc cctattcttt
    17581 ttatttgtta agatttacag ctgtacattt ataaattaca cctttatcat aaagagtgtg
    17641 gtaagataag tcaagcaaaa aaaatgaaag gatgacaact gatgaagtat tctctgcaat
    17701 ttagtgatgc aatccatgta cttgcctata ttgaaatgtt tcaagatacc cgatcacttt
    17761 ctagtgagat gattgccagt agtatcgaaa caaatgcagc aaatgtacgt aaaatcatga
    17821 gtcagctcaa aaaatccggt ttgatcttta caaaaaccgg aaaaccgcag ccttcccttg
    17881 ccaaaagtcc agatcagatt tctttactag atgtctatcg cagcatcgaa ggtaatacac
    17941 agcttatcca agtcgatcca aaaacaaatc caaattgcgt cgttggtgcg aatatccaag
    18001 aagctttaga agaaagctac gctcggctgc agaaaaaggc agaagaagaa atggctaaga
    18061 tcacacttga tagtctgata cataaaatag ccgttttgga aaaagaaaaa agaccagaaa
    18121 acacaggcct cgtagagaga tttttataat tctctctact gtgcctgcat ttttctgatc
    18181 ggaatcgtct acataaattc ttttattctc cgggggacaa aagccttgtc atgccccttt
    18241 ttcctctcta atgctcaggt caaagcgctg aagtcatgac gtcttgataa acggtgttca
    18301 agtagctgac cctcggcatt agttctgaaa aatgcaaaat atggaaagct atttcccatt
    18361 tttcctctct aatgctcagg tcaaagcgct actttcacga cctctatatt atcatggttt
    18421 attgactacc ggtatccaga tttctcccat atatttcccg ttggtaactc ccatttcgac
    18481 tacagcattt ggacccccaa cataggcgta atcttctact tctcttaaaa catgcccaaa
    18541 ggccgtattc gtcaaatcat ttcttaattc ttcaggcgat tctgctaaag cgcttacaac
    18601 aagatacgtt ccttttggga atgggatgat tcgcgtagtg tttggaacat cctgactcgt
    18661 ttgaacaccg acatagtaca tcattttccc gttatagggt tcgttgactg taaagaaata
    18721 atgattttca gcagcttgtt tcaatgcatc tattgttcca ttaccgataa ctttttgctc
    18781 aaatgcttgt ttctctgcag ccaaaccgac aaaatccgta ttgctactct tcaattccac
    18841 accaataccc gtcaccgtaa aatctggttt ttcttcgatc ctatactttg ccatttctcc
    18901 caccctttct attatattaa gttcatctta cataaaatta aagggaaatg acacgattac
    18961 gctctttttt ctagggatat ttttattttt taactatttt tttgctttca ctgcaatcca
    19021 aatctcactg taaacattac tgaaatcctc tccccatttt gtaaaagaga tctcgggagc
    19081 ttcgactaac ccataatctg aagaaggaag ccattctgca tagattttcc cccaagtatc
    19141 ttgtaaagtt tggggaaatg gccctttatt aggaaaaatg gcccaagtgt gttcttctat
    19201 agcaagcatt tctaaatcag cgtacggatt ttcttttgtc gtagcaaagc caatcatgtg
    19261 catcaaactg cccttttctt ccaagcggtc tccatcaaat ccataagaaa cgttgattac
    19321 ttgatttgga tataaatctc ctaacttatg catctcttcc ctttgagtct ccgtgatcgt
    19381 ctgcgctaac ttttgtattt cttgattgac tccttcaaat ttgacaggaa cttttttcgc
    19441 cacacctgcc acataaaact gttctttctt ttcgatacga aattccatcg attttcctcc
    19501 tctgacatca ataaaaaatg tcaagcgtgg aaaagatttt tgtatgccgt atctgctgat
    19561 ttctgaaggc agatatcctg accaatcacg aaaagctctt gaaaaacctt cgactgtttc
    19621 atatccatat ctaaacgccg tttctgtcac tcttgatcca tctagaagat cgcgattagc
    19681 caaagccaat ctacggtttt tgatatagtc cattagcgac atccctgcaa taaacgtaaa
    19741 gatgcgtttt aattgatatt cagagattcc tgtattttcg gctattattt tataggaaag
    19801 tccttctgtc aaatgttctt cgatgtaatc gatcaattgg ttcagatctt taagcatatt
    19861 tatcttcctc cttgattgcc tttttatcat attatcaaag aaagtcaatt acttgatgaa
    19921 tcaggaacca atttagtcag atgtagaaaa tgttgtatgg atctaaagaa aattctcaag
    19981 cagcgtttcg taacggataa ttggtattat ctgcctatct atgttttacc tttagaaaaa
    20041 taaattttgg ggaagacaga ttctaagtaa acaaagcggt aaaaatatct tttattccct
    20101 tagttaatcc gcttactacc tactgtacaa agcaaattgt tgttcaaact gctgatcaga
    20161 acgctgcttg gatttttctt t
//
LOCUS       DARPZJ010000046        19195 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.048, whole genome shotgun sequence.
ACCESSION   DARPZJ010000046 DARPZJ010000000
VERSION     DARPZJ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.048"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="SLE23_002019"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="SLE23_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HEI8468905.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="SLE23_002020"
     CDS             complement(1819..3042)
                     /locus_tag="SLE23_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HEI8468906.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="SLE23_002021"
     CDS             complement(3073..3912)
                     /locus_tag="SLE23_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEI8468907.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="SLE23_002022"
     CDS             complement(3929..4609)
                     /locus_tag="SLE23_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8468908.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="SLE23_002023"
     CDS             complement(4611..5684)
                     /locus_tag="SLE23_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8468909.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5740..5978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6021..6254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6331..7002)
                     /locus_tag="SLE23_002024"
     CDS             complement(6331..7002)
                     /locus_tag="SLE23_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8468910.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="SLE23_002025"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="SLE23_002025"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HEI8468911.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="SLE23_002026"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="SLE23_002026"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEI8468912.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="SLE23_002027"
     CDS             complement(10885..11751)
                     /locus_tag="SLE23_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEI8468913.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="SLE23_002028"
     CDS             complement(11911..14004)
                     /locus_tag="SLE23_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEI8468914.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(14753..15376)
                     /locus_tag="SLE23_002029"
     CDS             complement(14753..15376)
                     /locus_tag="SLE23_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468915.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(15535..16932)
                     /locus_tag="SLE23_002030"
     CDS             complement(15535..16932)
                     /locus_tag="SLE23_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8468916.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRWVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(16964..17935)
                     /locus_tag="SLE23_002031"
     CDS             complement(16964..17935)
                     /locus_tag="SLE23_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8468917.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            18309..18734
                     /locus_tag="SLE23_002032"
     CDS             18309..18734
                     /locus_tag="SLE23_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468918.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT         5551 a         4068 c         3231 g         6345 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    14281 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    14341 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    14401 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    14461 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    14521 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    14581 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat acacggtgtt
    14641 caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    14701 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctgtt tttcattgtc
    14761 cataggattg atattgtcct tgtgatgact cattcgtaat aattgaggct tgattttctt
    14821 cacttcccgt tatcgtttgt ccactgccag aatctgaagg acttgttcct gtcgactcgt
    14881 ttttttgaga agagacagtt gttttcttga cttgttcatt tgtctttttc cattccgcta
    14941 aacgatcggc gaccactttt ttgtctactt tttcagaata agcggtgatc acttttccat
    15001 ttttcaaacg ggctactttg tcgccatcat gagtcaaaag caaaacggtc aaatgcttgt
    15061 ctttaaattg atattgtctg agagaaatcg cactaagtac gtcatcgata ttaataaatt
    15121 gattttcttc ttttcctttt ggcaaataaa tgtccaattc gcctttttcg taattggcag
    15181 ttattttata ctccgcccac caataagttg agaattcttt tttgaaatta tctactgatt
    15241 ctttgcttgc tacgattttt tctgtttctt tctgagcaag atctgctgtc atttttcctg
    15301 aaaatgctgc ggataaaata agcagtaaga aaaaaccgaa taaccaaaag agaagaaacg
    15361 gtcttttttt cctcatgctt tcctccactc ctatttaatt ttgactattc tattatatac
    15421 aaaaaatgaa atagaaagac aaaaaagttg aaaaagatcg taaataattg aacttctttt
    15481 tcacaaaatg gtaagaatgg agaatttcac gcatttgctc tcaactattc tttcttaagc
    15541 ctcaaatccg tttttatctg atacgtcttt gaaccaatga cccgattttt tgattgttct
    15601 ttttccatct tgtgctaagt ctactgaaat aaagccatat cgattcttat atgcattggt
    15661 ccacgaccag ttatccatac atgtccacat atgatagcct aaacaattgg caccttcttg
    15721 aatggcttga tggacatatt tcagatgaga ttggacaaat tcgatccgat aatcatcgtg
    15781 gatcatgcca tcttctttga taaatcgtgc ttcgttttct acacccatac cgttttcaga
    15841 aataaagcag tcgatatttc cataatgatc tcgtacattg atcaaaatat catagattcc
    15901 ttgttcatag atctcccatc cgcgataagg attcatttta cgaccaggca tttcataatt
    15961 gtcgaaataa tcctcaggca ttggaccgtt tttagtatcg attggtgttt cttttgcttt
    16021 tacccagcgt ggctggtaat aattgatacc taaaagatct actgtatttt ctttgataac
    16081 cgtcaaatcc tctgcatgga tcacaggcat gagatcaagt tcttttacta tctcaatcaa
    16141 ttcacttgga aactcgcctt ttacagctgg atcaaggaat gaacgattga agaacgcatc
    16201 tgctatttgc gctgctttaa catcttcagg gtttgattcg tctcttggat agcttggtgt
    16261 cagattcaag atgataccaa taacaccacc ttgctccatt tcatggtaag atttgatggc
    16321 taacgctgaa gccaacgctt catgatagcc aacttggatc gcttttttca tatctgactc
    16381 ttctggataa tgccatcgat ataaataacc tgcttcgact ggaacgattg gttcattatg
    16441 agtaaaccat ttttttactt tcgaaccaaa caattcaaaa caacttttgg catatttttc
    16501 ataggcttca accgtttctc ggttcaacca tccgcctttt tcttgcagat acatcggcat
    16561 atcgaaatga tacagattca caaagggttc gataccgttt tcaatcaact catcaaaata
    16621 acgatgatag aaacgaacgg cttcttcgtt gattgttcca gattcatcag gtatcaaacg
    16681 gctccattgg atagatgttc gaaatgaatt atgcccagtc tgtttcatca actgtacatc
    16741 ctcttgatac ttcgtataaa cttgcgaggt tttttcaggt cctacttgat caaagaactt
    16801 ttgcggttct tttttgtacc aataatcaaa aatgttctct ccttttccat cgcctgaaat
    16861 ccttccttct gtttgtgggc cacttgctgc agaaccccac caaaaatttg ctggaaattg
    16921 atattttttc atcaaagcac ctctttttct tttttagttc gttttagttg attccatgta
    16981 tgatattttc catcacaatc actttttcat tttcttcctc ttcttttttg attcgtttta
    17041 acagctgttc tgctgctcgt tccccgattt tatctgttgg tggcgtgatc gtgattttcg
    17101 gaaggatact cagatcgttt ttatctaaat aatcatagtg actgaacgca atatccttcc
    17161 cgattctgac accttcttga ttgaaacatt cgatggcacc aatcgacata ttgtaattgc
    17221 tgacaaaaat agcagttgcc cctttttcta ataatgcttt tgccccgtaa tagccgcttt
    17281 ttctagaata gtctcctgta aagacctcta attggatcga tggatcattt tggaccgctt
    17341 ctttggctcc tgctaaacgt tctcttgcta cgtagtctgt ttgagtggca gcaataaatc
    17401 cgattttttt atgtccttgt tcaccatgat gagcgatcac ttttgctaca ctttctcgat
    17461 cattcactaa tattgtatca atacctgctg gtccttctgg acaattcaat gcgataactg
    17521 gaatactcat ttttgtgagc atttcaaatc cagaccactc ttcttcggat aagaagacaa
    17581 tcagcccatc gatcacatgc ttcatcaggt attcaatttt ttgttcaatt ttttctggct
    17641 gatcggcaaa cccgcttaat aataagctat acccattttc ttcagctact ctttcgatcc
    17701 ctgagacaac ttccgaccca aaacggctgg aaatcccgtt tatcaaaagt ccaatagaga
    17761 agcttcgatt attcttcaac cctttagcaa tgatgttttc tttatagtcc aacgctgaaa
    17821 tcgcttctgc tatttttttc atgttctttt ccttcagttg ctgaccattc aagtaacggg
    17881 aaactgttcc cactgaaaca ccagccatct tagccacatc acggatcgat gccatacatt
    17941 ctcactcctg ccagttacat ttgatttctc tttcttgttg ttcgattatg atgaccgcat
    18001 tctttgcata gtgttgcttg tcatcaatat ccatataact aaagtcttca gtagagcaac
    18061 ttcctctcac tattaattat acttaaacaa gtatttgaac cggttcattt ttaatatagc
    18121 atttttttaa aagattgcaa cactttttta aaacgctttc tgaaagtggc ggattttttg
    18181 cctttttaaa attttattct aaaatttact ctatttgtgg gtgttttgtg cgtttttctc
    18241 ttccatccgt ttgaagtttt acattccaat ggtataattt ctttatccta tcaaatgggg
    18301 gaagtatttt gaagaaatta atcgtactat ttattttgtc tgcgggactt ttgacattga
    18361 ctggctgtga tttgtttggc ggctctgacc aatcctcgga cgaaacaacc gattcttctg
    18421 tcttaaaagc ggaaaaagca gataccacca acagtgtata tacgctaaaa gtacgtaaag
    18481 atatggattt atccgcggga cagttgacat ttacagataa aaaaatggaa tggacacgca
    18541 cgtatcagac acaaggaact gattcttctg aatcatctga agaaaaaaca gtgctgacag
    18601 atatcaagat cactaccaaa gatgacgaat atattatttc aggaaaagaa aataaaaaag
    18661 aaacaacagt catatttaca aaaatcggta attaccgttt gaaggatgag gatggcaaca
    18721 tctacagtct atagtgccgt ctgttggatc ttcttttgtt tctccccttc ttttctgcta
    18781 tagtaaagaa gcaagatgat tgtaaaggag acgaaatgga tgatcgatag tcctgattat
    18841 tgtacatgta ataacaacaa aaatatccat acagaattta atgaccaagg aagcttgagc
    18901 atatgcgaca actgtcacaa actagtcaaa gattcattta aaacatttga atcttatcct
    18961 gttcaaaatt atgtaaaaag tagaagaaga taaacaaatc caagcaaaac tcactatggc
    19021 tgatttttat gaacttcaaa ctcagcttct tcctttgatc aagcttcatc agtaaaacaa
    19081 acagtggatc atttcagttt acaaatcaaa gagtaaagat ttatttattt caaatatttg
    19141 aatataaaat aaccaaacga tagaaaggct tattctacat cacgtagtaa ttttt
//
LOCUS       DARPZJ010000047        18895 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.049, whole genome shotgun sequence.
ACCESSION   DARPZJ010000047 DARPZJ010000000
VERSION     DARPZJ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.049"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(21..251)
                     /locus_tag="SLE23_002033"
     CDS             complement(21..251)
                     /locus_tag="SLE23_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468919.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="SLE23_002034"
     CDS             complement(687..1253)
                     /locus_tag="SLE23_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8468920.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="SLE23_002035"
     CDS             complement(1253..2209)
                     /locus_tag="SLE23_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEI8468921.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="SLE23_002036"
     CDS             complement(2209..2865)
                     /locus_tag="SLE23_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEI8468922.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="SLE23_002037"
     CDS             3235..5253
                     /locus_tag="SLE23_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8468923.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="SLE23_002038"
     CDS             5680..8094
                     /locus_tag="SLE23_002038"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEI8468924.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="SLE23_002039"
     CDS             8442..9995
                     /locus_tag="SLE23_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEI8468925.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="SLE23_002040"
     CDS             complement(10376..12160)
                     /locus_tag="SLE23_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468926.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="SLE23_002041"
     CDS             complement(12175..13896)
                     /locus_tag="SLE23_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8468927.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="SLE23_002042"
     CDS             13996..14757
                     /locus_tag="SLE23_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8468928.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="SLE23_002043"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="SLE23_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18895
                     /locus_tag="SLE23_002044"
     CDS             16664..>18895
                     /locus_tag="SLE23_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468929.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3353 c         3786 g         5551 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggt
//
LOCUS       DARPZJ010000048        17106 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.050, whole genome shotgun sequence.
ACCESSION   DARPZJ010000048 DARPZJ010000000
VERSION     DARPZJ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.050"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            7..1398
                     /locus_tag="SLE23_002045"
     CDS             7..1398
                     /locus_tag="SLE23_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEI8468930.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="SLE23_002046"
     CDS             1414..2454
                     /locus_tag="SLE23_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8468931.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="SLE23_002047"
     CDS             2473..3558
                     /locus_tag="SLE23_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEI8468932.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="SLE23_002048"
     CDS             3591..4553
                     /locus_tag="SLE23_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEI8468933.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="SLE23_002049"
     CDS             4546..5979
                     /locus_tag="SLE23_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEI8468934.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="SLE23_002050"
     CDS             5976..7046
                     /locus_tag="SLE23_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468935.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="SLE23_002051"
     CDS             7033..8454
                     /locus_tag="SLE23_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEI8468936.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="SLE23_002052"
     CDS             8467..9474
                     /locus_tag="SLE23_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEI8468937.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="SLE23_002053"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="SLE23_002053"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HEI8468938.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="SLE23_002054"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="SLE23_002054"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HEI8468939.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="SLE23_002055"
     CDS             11608..12285
                     /locus_tag="SLE23_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEI8468940.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="SLE23_002056"
     CDS             12275..13417
                     /locus_tag="SLE23_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEI8468941.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="SLE23_002057"
     CDS             13430..14407
                     /locus_tag="SLE23_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEI8468942.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="SLE23_002058"
     CDS             14407..15315
                     /locus_tag="SLE23_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEI8468943.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="SLE23_002059"
     CDS             15316..16068
                     /locus_tag="SLE23_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HEI8468944.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="SLE23_002060"
     CDS             16073..17020
                     /locus_tag="SLE23_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HEI8468945.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6163 a         2190 c         3090 g         5663 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gataga
//
LOCUS       DARPZJ010000049        17100 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.051, whole genome shotgun sequence.
ACCESSION   DARPZJ010000049 DARPZJ010000000
VERSION     DARPZJ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.051"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..153
                     /locus_tag="SLE23_002061"
     CDS             <1..153
                     /locus_tag="SLE23_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEI8468946.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFSFSVSTEIKV
                     LMGITA"
     gene            159..575
                     /locus_tag="SLE23_002062"
     CDS             159..575
                     /locus_tag="SLE23_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468947.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            681..944
                     /locus_tag="SLE23_002063"
     CDS             681..944
                     /locus_tag="SLE23_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8468948.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDLKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            944..1216
                     /locus_tag="SLE23_002064"
     CDS             944..1216
                     /locus_tag="SLE23_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEI8468949.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTYEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1293..1622
                     /locus_tag="SLE23_002065"
     CDS             1293..1622
                     /locus_tag="SLE23_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8468950.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1612..1899
                     /locus_tag="SLE23_002066"
     CDS             1612..1899
                     /locus_tag="SLE23_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8468951.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            2185..3042
                     /locus_tag="SLE23_002067"
     CDS             2185..3042
                     /locus_tag="SLE23_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8468952.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            3043..3591
                     /locus_tag="SLE23_002068"
     CDS             3043..3591
                     /locus_tag="SLE23_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468953.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(3884..4831)
                     /locus_tag="SLE23_002069"
     CDS             complement(3884..4831)
                     /locus_tag="SLE23_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HEI8468954.1"
                     /translation="MHLEFSDYESLLVKICEDYYLEDINISEISKKYGITRYKALKYI
                     EDAREKQLVSISINSPYARNYELEEIFKNYFKTNIYILKSSEDLSQHDLLFSKFAADY
                     IQELIKKANVVALSWGDTVYKVIDQFKMGAREELIFTQFIGEIGKYNSLAGSTRLVQK
                     AAERYESSYLTLSIPLYVINETARELMALEPSLANTLATASHADMLISGIGTLSSIDS
                     VEPWNKHRKILFPSMTDTVGFLYGRPFNINGEFIKASEDKTFGLSLKEIFDIPKRIGI
                     CKSKFKAESCLGALNGNFFTDLFLDEKTAWKILSLIKKE"
     gene            5019..6206
                     /locus_tag="SLE23_002070"
     CDS             5019..6206
                     /locus_tag="SLE23_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEI8468955.1"
                     /translation="MLDEVLEIHKKNVGVLRMETTEAVQDDQDLAKMYTPGVAELSLM
                     IEKNHALARELTISGKLVAVITDGSAVLGLGNVGNQAGLPIVEGKALLYKNLAGVNAI
                     PLAIEQKSVDEIVQTIVNLQNSFAGIHLEDIAAPKCFEIEEKLQEKLSIPVYHDDQEG
                     TAIVVLAGLINAAKIQRKTLTELRVLINGMGASGVATARLLIAAGIKNLTLVDKQGRL
                     KKQDSTLNKYQRELLDHIHDTNNNASVLEDAIVGQDVFIGLSIGNVLTPEMIGKMNDN
                     PIIFALANPVPEITPDLAKESGAKLIATGSSKYPNQVNNILVFPGLFKGLLLSKANKV
                     DLSLQLEVAKQLAAKVAEPTVEKFIPNVFDEGVANVVSQAVLDYLQKLKENEDNIHAE
                     NIK"
     gene            6187..7491
                     /locus_tag="SLE23_002071"
     CDS             6187..7491
                     /locus_tag="SLE23_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEI8468956.1"
                     /translation="MLKTLNRIKIGFIPLSLYIILVLAYLAMTISNIVPENDMLVSLG
                     IMTVFAYLLEEIGKTIPILKDLGGKVLVVTFLPAFLVYKHWLPQSTVTVVSDFMNNNN
                     FLMFFITLLVVGSIASMNRQTLVKATSRIIIILILCDVIGSLIGTGVGILLGLSAWNA
                     YFFIVAPIMAGGVGEGAMPLSIGYAAILSGMGQNDIFGKILPCVMLGSLVAVLLSGML
                     KKIGEKYPQLNGQGNLIDGDDEHLENLKGSAKPVNIEKTLLAGVVAITIYFVAVYVEH
                     LLKSLLGFSIPSPVILLVSLMGAKMLGFIPKNIEEGGNSLYGFTVRGITPPLLFGVGV
                     AKTDWLELIEVFKNPATIVTIIVTVVAIVATAFIAAKFLKMYPVDTAIAVSCCSGQGG
                     TGALAILAAGDRMELMPFAQVAVRLGGAMTVTFAIFLMGLLS"
     gene            7517..8530
                     /gene="citC"
                     /locus_tag="SLE23_002072"
     CDS             7517..8530
                     /gene="citC"
                     /locus_tag="SLE23_002072"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEI8468957.1"
                     /translation="MFDQTDIQRLFLKNNYIKDQWENLLLDSGIQKKQIEDFQHLDQT
                     LGIYHKEKLVGTVSYQNNVIKYIAVSEKYKDGGHTFNVLVSAIIQAMSQQEIFHYIVF
                     TKPRYQKSFNFLGFETIVSTPKIAVLEMGDSSIKQYLERIPKVNGEKKAAIVMNANPF
                     TEGHYYLVKQAANNNDWVYVFVLEKEQNLFSTKDRLKLVQQGLQKLKNVIVLSGGEYI
                     ISPATFPTYFLREDDEIAKEQMVVDATLFKERIATYLDISARYVGEEPLSPMTRSYND
                     ILETILPPEIKVHVLARKKTEQHQVISASQVRKAYLAGQLEKIKYMVPETTYQYLKNK
                     RER"
     gene            8534..8827
                     /gene="citD"
                     /locus_tag="SLE23_002073"
     CDS             8534..8827
                     /gene="citD"
                     /locus_tag="SLE23_002073"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEI8468958.1"
                     /translation="MEINKSAIAGTLESSDVQIMISPNTEGIEIDLDSQVIEQFGKQI
                     KKVIYDTLAVYQIKNVKLKVVDKGALDCVIVARLKTAIHRSLGIQHQETPWEV"
     gene            8832..9737
                     /gene="citE"
                     /locus_tag="SLE23_002074"
     CDS             8832..9737
                     /gene="citE"
                     /locus_tag="SLE23_002074"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEI8468959.1"
                     /translation="MMKERLRRTMMFVPGNNPAMIKDAGIYGADSIMFDLEDAVSMAE
                     KDSARMLVAEALKTVDYGDTELIVRINDLHSEFGRADIFAMVKAGAHVLRLPKTETSE
                     DITEVEKVIIEAENYHNVPIGRTLMMAAIEGASGVLNAPAIAKASDRLIGIAIGAEDY
                     VTNMKTKRYPDGNELFFARSMIVHAARAAGISAFDTVYSDVDDMEGFLNEVRLIHQLG
                     FDGKSCINPRQIPVVNTVYQPSIKEIKRSLDIISAIEEAKEKGSGVISLNGKMIDKPI
                     VERAQRTLMLAKASRLIDEEGNIHA"
     gene            9730..11289
                     /gene="citF"
                     /locus_tag="SLE23_002075"
     CDS             9730..11289
                     /gene="citF"
                     /locus_tag="SLE23_002075"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEI8468960.1"
                     /translation="MHNKQRRSIPSSVLTKYKKEFQSVSLSPQTIQRCAPKVTTVTNQ
                     TNKLMHSIKEAIEKSGLKDGMTISFHHHLREGDFVFNQVMAVIREMGIKELTLAPSSL
                     TNTMNEMVIECIKDGTVTHITSSGMRGSLGEFISHGGMDNPVILRSHGNRPRAIESGE
                     LKIDVAFLGVPTSDDYGNANATVGKSVFGSLGYAKVDAQYADKVILLTDHLVPYPNTP
                     ISIPQTQVDYVVEVEAIGDPNKIGAGATRFTKNPKELKIAEMVKDVIVHSPYFKDGFS
                     FQTGTGGAALAVTRYLASEMEEKQIKASFALGGITKPTVDLLEKGLVEKVLDVQDFDK
                     GAAEGMARLENQQEIDASFYADPSNKGAVVNQLDVAILSALEIDTNFNVNVMTGSDGV
                     LRGAIGGHQDAATAKLTIISAPLVRGRIPTVVNDVTTLITPGKSIDVLVTEVGVAINP
                     QRKDLIAIFERIPQIPVFTIEELQQKAEKIVGIPEPLQFTDRIVAYVEYRDGSILDVV
                     RQVKEFEEERS"
     gene            11286..11843
                     /gene="citX"
                     /locus_tag="SLE23_002076"
     CDS             11286..11843
                     /gene="citX"
                     /locus_tag="SLE23_002076"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEI8468961.1"
                     /translation="MMFDTGEIQEIEDILIHKEQRANLQSNLLSKYSNSSLMVFTLNI
                     PGPIKNNPMIEQVFRQGQQSIQQMFLKKKVEMTYTKEINLPSGLDWYVIVTEAPLNLK
                     KWLVTLEEQDALGRLFDLDVLFKKGEQITIVSRQALNHGERPCFICGKSAKVCARNRT
                     HTVKEMQKKIEQIVADSLKGALKHA"
     gene            11836..12699
                     /gene="citG"
                     /locus_tag="SLE23_002077"
     CDS             11836..12699
                     /gene="citG"
                     /locus_tag="SLE23_002077"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEI8468962.1"
                     /translation="MHDNIQKIAQEAQLAMLYEVTCINKPGLVDPVDPGSHQDMDIFT
                     FLQSSVVLTPYFEEFIQTGLDRQHQPIEETFMAIRQIGLEAETAMFSVTNGINTHKGA
                     IFSLGIFLAICGRLTIWKVPCKKSFFQKEIQKMTKNLLNDFGKIDQTKPKAWTWGEYL
                     FVNHGLTGIRGEAKRGYPCVFDRGLPYYQAYQGSQQDKMIDTLLFLSMEVEDTNLIKR
                     SNNRHVFEEYQLLIRPYFELGGVKTIQGKKYLDYLNQQFKKKNWSIGGSADLLILTIF
                     LDKIMDKGWLC"
     gene            12933..13342
                     /gene="tnpA"
                     /locus_tag="SLE23_002078"
                     /pseudo
     CDS             12933..13342
                     /gene="tnpA"
                     /locus_tag="SLE23_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13979..15151)
                     /locus_tag="SLE23_002079"
     CDS             complement(13979..15151)
                     /locus_tag="SLE23_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8468963.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRIGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LIASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWITFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNCVSANRLIGAVLIDQHDEWLSSSRKYIKFAK"
     gene            15825..16637
                     /locus_tag="SLE23_002080"
     CDS             15825..16637
                     /locus_tag="SLE23_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468964.1"
                     /translation="MILLAVSMSLLIYTHILSTFMSVIVIGFLFIGSLFSKRKERKEM
                     SNLISNMIKAVGWTILLTAYVWYPMLQQVLHQKINRPFRTKLQERALNISDSLIGAVN
                     NDLVTFTMGTIGVVSFILPLFFKKKFANKEKIINFCAVTTWFLSTNLFPWEFLQKTPI
                     QIIQFPWRILGFQVLFGSLILIIVFLKWKTSNKKSMCSLVGIVLLIFTVTVATEANYS
                     QKIQSYKGRLIMTKKDVTLYTTSRTGGLYDYAPLDALKYKDHLKKHEVKVYD"
BASE COUNT         5992 a         2562 c         3293 g         5253 t
ORIGIN      
        1 aataaatttt atcaaagtct ccgtacagcc tcttccacga ttaagggcat ggagaccatt
       61 cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct tcagcttttc ggtgtctact
      121 gaaatcaagg tattaatggg aataacagcc taagatattt ggagttcaga gagggcgcgt
      181 ttgattttca aacttcgcaa cagaaccgaa aatttatacc ggaagatttt caaaacttac
      241 agttagaaaa catgcgttta gaagatttat ttagattagc agatgatgat aagtatagat
      301 ttgaagtttt gaaaattaaa aagaatgaac tattgaataa gttatatcct gagaatgcga
      361 taaaagcaca ttttggtgat gctaatcata tgtatagttg gttcattcct aaaagattta
      421 gagggaaaat caatgctgga gatcaagtga aagtactcaa tcgaaatagt acagatgtcg
      481 taatgataac agatatctac gtagaagatg aagttataat caaatatatg aagcctgtga
      541 taaaacttgt taataaaaat aaaggaaacg gataacactt tacaatgctg ttttggtact
      601 ccaatttaaa caaaacaatc gaatttacgt acttaattaa gtacgttaga atggagatat
      661 aaattagagg gggagtagat atggcaaaaa cagtcttaaa tcctagctca gcacggaaaa
      721 atttttataa gttgttgaaa gatgtaaatg agaatcatac ggaaattgaa atcattagtg
      781 agcgcagtga aaataatgcg gtgcttattg gtttggatga tttgaaagca atcaaagaaa
      841 cgctattact tgagcaaata ggcactttgg gtgttgttcg taagcgagaa aaagatgata
      901 gtggatttac taatgttgat gaaattgatt gggataactt ataatgaata actattctgt
      961 gatgattaaa aactcggcta aagctgattt aaagaaaatc aaacagtcta atttgaaacc
     1021 tcaatttgag aaggttattc agactttaaa ggaagatccc tatctcccta cccaatcatt
     1081 tgagaagtta aaacctacat atgaaggtag gtattctaga agattgaata gacaacaccg
     1141 ggttgtttat aaggtagatg aagatgaaca cgtggttgaa atttattcag caaggacgca
     1201 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
     1261 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
     1321 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
     1381 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
     1441 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
     1501 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
     1561 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
     1621 gaaatcgttc cttcaaaaca tgtcattaag tatttaaaaa agctaaaaga gaagccattg
     1681 aaagaaaaat ttttgaattt aatttatgat gaaattgcga ttgatccata taagggtgaa
     1741 caaaaaactg gggatttatc aggtatttgg tctagtgggt tcaaatatgc gggcacaaca
     1801 tatagagtag cttacgagat tatagaaaac aaggttattc cagtattgtt atgtggaacg
     1861 catgaaaact tttatgaaca gttgaaaaaa ttaatctagt gatttgttgt cgttcttaag
     1921 aaggacggct tcttttttat cgaaaatctg attcgtctac atgactaaag tcgcgagtat
     1981 tctctgcttc tcgataaatt aaataacgtc attactttga ggaaagctat aaatcaatat
     2041 atttcaactt ttccttattt atgtactacc ttttacttat taattataag gtagtacata
     2101 tatatctttt ttttggtagt aactaaaaat aaatatgtta taatagtatc aaatgaatat
     2161 tgctaaaaga aaagaggtag gaacgtggta gcgaagaaat atgtaattgg taattttaaa
     2221 ggtggcgtag gtaaaagtac gtgcgcgcaa atgttagggt ttgaatcagc agttaatgaa
     2281 ggaaaaagaa ccttgataat tgacttggat atgcaaggaa atacttctga tgtgatgaac
     2341 ttaacgcata tgaacttcac taacgaagaa ggaggcggag aaggtgaacc gattgtttac
     2401 gaaaatactg tgactgacgt gttgataaac aatcttccac ctaaagaggc tgtctataaa
     2461 gtaatcaata acctctatat acttccagca gatatgtcct ttgaaatgta tgatgattgg
     2521 atcaaagacc aatataatga ttcattatcc caattcaaat atatgaaaga aaagctagaa
     2581 ccattatttg atgagtttga cgtcatctat ttagatgtcc caccttctat ttctgtatat
     2641 agtaaatccg cgatgtacat tgcggactgg gcaatcgtcg tcttacagac ccaagtaaaa
     2701 tcgatgagaa atgcgatgca atatcttgag tatatggact tttttgtgaa agaatttgat
     2761 acaaatttat atgttgctgg tgttattcct ttcatgttgg aaagcggtga cgcagtagat
     2821 caggaaatgt ataaacaagc ccaagagatt tatggggaac atttgattaa aaatgttgta
     2881 ctcaaaaatg cgcgcttaaa acgatacgac ggatcaggta ttacgatgga gaagacaaag
     2941 aaaggtctct taaaacaatg ggatcgcaaa agccacgaat tatttatcag tattttgaaa
     3001 gaattggaag aacacgagaa ttggtatgcg gaggtggagt aattggctga catcaaagga
     3061 cttgatattt ttgggaacaa caaaggactc gccaaaataa aaaaagaagc agaagcaaag
     3121 aaaaagcagc aagcaattac accatctgaa aataagcaat tagaagtgca ccaagttcaa
     3181 gaaataaaaa cttcctccaa tgttgaaaga cagagtagag gaagaacaaa aaaagttggc
     3241 gcaccaatca gaaagtttga taaggtttat tccaccaagc atcctttaaa actgtcgact
     3301 ttgttaaatg cgacttccag agttttagta gaaaagtatg agactaatat gacaagagat
     3361 gaattgctta gaaaagcttt agatgagtat attaaacaga atcttacgca agaagataag
     3421 caagatttgt ttaatgacgt ggtgaaagaa ctagacttgt tcagagaaaa atatccaatt
     3481 gttccagaat tagatgaccg tggagaaata ataagaacta ccagtcagat aaaacaagat
     3541 accgaagact cactgcgcaa agggtgggga atgaataata aagttagata gaaccccctt
     3601 tttatagcat aaaaaagatt tagaaggata tatgatctgc atgagaagta caataaaatt
     3661 aataagaagt aacattaacg aaaaaacgtg gaaattattc agtgaataca aagaaattaa
     3721 atcttgaaaa gtaatggagt atggcttgga aaagttcaaa aaatatcaag acaagcttct
     3781 caaaaaaagg gattttgata tccaataaaa agagtgaatc attgtactgc cctccaaaaa
     3841 agtagtacca aaaatctaaa ttttttggag gattttacat gactcactct ttttttatca
     3901 aagaaagtat tttccaagca gttttttcat ccaaaaataa atctgtaaaa aaattaccat
     3961 tcaaggcgcc taaacaactc tccgctttga acttactttt acaaatacca attcgttttg
     4021 gaatatcgaa aatttctttt aaagaaagac caaaagtctt atcctcagat gctttgatga
     4081 attcaccatt gatattgaag ggtcttccgt aaagaaatcc aacagtatcc gtcatgcttg
     4141 gaaataggat tttacgatgc ttgttccagg gttcgacaga atcaatagag gataaggtgc
     4201 caattccaga aattaacata tctgcatgcg aagcggttgc taaggtatta gctaaagaag
     4261 gttctagagc cattagttca cgtgcagttt cattgatgac atataaagga atactgagag
     4321 tcaaataaga agactcataa cgttcagcag ctttttgaac taatcgtgtg gagccagcta
     4381 aggaattata ttttccgatt tcgccaatga attgagtaaa aattaattct tcacgagcac
     4441 ccattttaaa ctgatcaatc actttgtaaa cggtatctcc ccaagatagt gcaaccacat
     4501 tggctttctt aattaattct tgaatgtaat cggcagcaaa ttttgaaaat aataaatcgt
     4561 gttgtgataa gtcttcacta ctttttaata tatagatatt cgttttaaag taatttttga
     4621 agatttcttc tagctcataa ttcctagcat acggagaatt aattgaaata ctaactaatt
     4681 gtttttcacg tgcatcttca atatatttta aagctttata tctggtgatc ccatattttt
     4741 tagaaatttc actaatattg atatcctcga gataatagtc ttcacaaatt tttacaagga
     4801 gtgattcata gtcagagaat tccagatgca tagtatagct cctaactttt tcaaatagat
     4861 attttttctc attataccaa aaaaattgaa tttagtcttt ttttaaattt ttaaaaataa
     4921 gcatcatttt tttaaaattt aaaatgaaag ggttttttta ttttaaaaaa agtgttaaag
     4981 tggttttgta attaaaaaat gtaaaaagga gtgaaggtat gcttgatgaa gttttagaaa
     5041 tccataaaaa aaatgtaggt gttttacgga tggaaacaac agaagccgtg caagatgatc
     5101 aagatttagc aaaaatgtac accccaggtg tagcagaact aagtttaatg attgagaaaa
     5161 atcatgcttt ggcaagagaa ttaacaatta gtggtaaatt agtggccgtt attacagacg
     5221 ggtcggcggt attaggtctt ggaaatgtag gaaaccaagc tggattacca atcgtcgaag
     5281 ggaaagcgct gctttataaa aatttagcag gtgtcaatgc gattccatta gccatcgaac
     5341 aaaaatcagt agacgagatt gtacaaacaa ttgtcaattt gcaaaatagt tttgcaggga
     5401 tccatttaga agatattgca gcaccgaagt gttttgagat tgaagaaaaa ttacaagaaa
     5461 aactttctat tcctgtgtat catgacgatc aagaaggaac agcgatagtt gttttagctg
     5521 gattgatcaa tgctgctaag atccaaagga aaacattaac tgaacttcga gttttgatca
     5581 acggcatggg agcatctggg gttgcaacag ctagactatt aatcgctgct ggtatcaaaa
     5641 atctaacatt ggtggataaa caagggagat taaagaagca agatagtaca ttaaataaat
     5701 atcaaagaga gttgttggat catatacatg atacaaataa taatgcaagc gttttggaag
     5761 atgcaatcgt tggacaagat gtttttatcg gtctttcaat aggaaatgtt ttaacgcctg
     5821 aaatgattgg aaaaatgaat gataatccga ttatttttgc tttagccaat ccagtaccag
     5881 agatcacacc cgatttagca aaagaatctg gtgcaaagct aatcgctaca ggttcttcga
     5941 aatatcctaa ccaagtaaac aatattttag tatttcccgg attgttcaag ggactattac
     6001 tatcgaaagc gaataaagtc gatctttcat tacaacttga agtagccaaa caattagctg
     6061 ctaaggtcgc agagcctacg gtagaaaaat tcatccctaa tgtttttgat gaaggagtcg
     6121 caaacgtcgt ttcacaggca gttttggatt atttacaaaa actaaaagaa aacgaggata
     6181 atatacatgc tgaaaacatt aaatagaatt aaaattggtt ttattccttt atctctttat
     6241 atcattttgg tactcgcgta tcttgcaatg acgataagca atatcgttcc agaaaatgat
     6301 atgttagttt ctttgggtat tatgactgtt tttgcttatt tattagaaga aattggtaaa
     6361 actattccta ttttaaaaga tttaggtggt aaagtattag ttgttacatt tttgcctgca
     6421 tttctagtct ataaacattg gctacctcaa agtactgtaa ctgtggtttc tgattttatg
     6481 aataataaca atttcttgat gttctttatc acactactag ttgtcggcag tattgcttca
     6541 atgaatcggc aaacattggt taaagcaact tcacgtatta tcattatttt aattttatgc
     6601 gatgtgattg gttctttgat aggaacaggt gtgggaatac tccttgggct atctgcttgg
     6661 aatgcgtatt tctttatcgt tgcgccgatt atggctggtg gtgttgggga aggagcgatg
     6721 ccattatcga ttggttatgc agcaatatta tctggtatgg gacaaaatga tatctttggg
     6781 aagattctac cgtgtgtgat gttgggaagt ttagtcgcag ttctactgtc tggtatgctc
     6841 aaaaaaattg gagagaaata cccacaatta aatggtcagg gtaatttgat cgatggggat
     6901 gatgaacatt tagagaactt gaagggttca gctaaaccag tcaatattga aaaaacattg
     6961 ttagcaggcg tggtagcaat aacgatttat tttgttgctg tctatgttga gcacttatta
     7021 aaatcactcc ttggcttttc tattccttca cctgtgatct tattagtctc tcttatgggg
     7081 gctaaaatgc ttggttttat ccctaaaaat atcgaagaag gtggaaattc gttgtatgga
     7141 ttcactgttc gtgggatcac acctccctta ctttttggcg taggggttgc aaaaacagat
     7201 tggttagagc tgatcgaagt atttaaaaat cctgcaacga tagtaacaat cattgtgacg
     7261 gtagtagcta ttgtcgctac agcttttatc gccgcaaaat ttttaaaaat gtacccagtt
     7321 gatactgcca tcgcagtttc atgttgtagc ggacaaggcg gtacaggtgc tttagctatc
     7381 ttagctgcgg gtgatcgcat ggaattaatg ccatttgcac aagttgctgt tcgactaggg
     7441 ggtgctatga ccgtaacgtt cgctatcttt ttaatgggtc tgctatcata agaacataaa
     7501 gaaaggacgt gaccatgtgt ttgatcaaac agatatccaa cgattatttt taaaaaataa
     7561 ctatatcaaa gaccaatggg aaaatctttt gcttgattca ggaatacaaa agaagcaaat
     7621 cgaagatttt caacatttag atcaaacatt gggtatatac cataaagaaa agttagtagg
     7681 aacagtatct tatcaaaaca acgtgattaa atatatcgcc gtgtctgaaa aatataaaga
     7741 tggtggacat acatttaatg tactagtctc tgcaataatt caggcaatga gtcaacaaga
     7801 gatttttcat tatattgttt tcacgaaacc gcgctatcaa aaaagtttta actttttagg
     7861 ttttgaaaca atcgtatcta ccccaaaaat agctgtatta gaaatgggag atagttctat
     7921 aaaacagtac ctagagagga ttcctaaagt gaatggtgaa aaaaaagcag caattgtcat
     7981 gaatgcgaac ccatttacag aagggcatta ttatttagta aaacaagctg ccaataacaa
     8041 cgattgggta tatgtatttg tactcgaaaa agaacaaaat cttttttcga cgaaggaccg
     8101 actcaaatta gttcaacaag gattacaaaa actgaaaaat gtcattgttc tatcaggtgg
     8161 cgagtatatt attagccctg caacgtttcc cacctatttt ttacgagaag atgatgaaat
     8221 agcaaaggag caaatggtcg tagatgctac tttattcaaa gaaagaattg ccacttattt
     8281 agatatctct gctagatatg tgggagaaga accactttcc ccaatgactc gttcatataa
     8341 cgacatactg gaaacgattt taccccctga aataaaagtt catgtccttg caaggaagaa
     8401 aacggaacaa caccaagtta tttctgcttc tcaagttcgt aaagcgtatc ttgctgggca
     8461 attggaaaaa ataaaatata tggttccaga aacaacctat caatacttaa aaaataaaag
     8521 ggagcgttaa gtaatggaaa taaataaatc agcgattgct ggaacattag agtcaagtga
     8581 tgtccaaatc atgatttcac cgaatacaga aggaatagaa atcgatttag acagtcaagt
     8641 gattgagcaa tttggaaaac aaatcaaaaa agttatctat gacacactag cagtttatca
     8701 gattaaaaac gtaaaactca aggtagtaga taaaggggca ttagattgcg ttattgttgc
     8761 acgattaaaa acagcgatcc atcgttcctt aggtatccaa caccaagaaa caccgtggga
     8821 ggtttaatta gatgatgaaa gaacgtttga gaagaacaat gatgtttgtt ccaggaaata
     8881 atccagcgat gatcaaagat gcaggtattt atggtgctga ctcgattatg ttcgacctgg
     8941 aagatgcagt gtctatggca gaaaaagaca gcgcaagaat gcttgtggct gaggcattga
     9001 aaacagtgga ttatggtgac acagaattaa ttgttcgaat aaatgacctg cactcagaat
     9061 ttggacgtgc agacattttt gcaatggtta aagccggcgc gcatgtatta cgtttaccta
     9121 aaacagaaac ctctgaagat ataacagaag tagaaaaagt gattatagaa gcagaaaact
     9181 atcataatgt tccgataggg cgaacattga tgatggcagc cattgaaggt gcttctggtg
     9241 tattgaacgc acctgcgatc gccaaagcat ctgatcgatt gattggaatc gccattgggg
     9301 cagaagacta tgtgacaaat atgaaaacca aacgatatcc agatggaaac gaattgtttt
     9361 ttgctcgcag tatgatcgtt catgctgcac gtgcagcagg catttccgca tttgacactg
     9421 tttactctga tgtggatgat atggaaggat ttttaaacga agtacgttta atccatcaat
     9481 taggttttga tggaaaatct tgtatcaatc cacggcaaat tccagtagtc aatactgttt
     9541 atcagccgtc aatcaaagaa atcaaacgat cactagacat catctcggca atcgaagaag
     9601 caaaagaaaa aggttctggc gtaatttctt taaatggaaa aatgatcgat aaaccaattg
     9661 tagaacgtgc acaacggaca ttgatgttag caaaagcatc acgattgatt gatgaggagg
     9721 gaaatatcca tgcataataa acaaagacgt agcattccat caagtgtttt aacaaagtat
     9781 aaaaaagaat tccaaagtgt ttcattatcg ccacaaacga ttcaacgttg tgcaccaaaa
     9841 gtaacgactg taactaatca gacaaataaa ttgatgcact cgatcaaaga agctatagaa
     9901 aaatcgggct taaaagatgg aatgacgatt tcatttcatc atcatttgag agaaggtgat
     9961 tttgttttta accaagtgat ggccgtgatc cgtgaaatgg gcatcaaaga attgacctta
    10021 gcaccaagtt ctttaacgaa cactatgaat gagatggtta ttgaatgcat caaggacggt
    10081 acagtaactc atatcacaag cagtgggatg cgcggcagct taggtgaatt tatttctcat
    10141 ggaggaatgg acaatcctgt gattttacgt tctcatggta atcgtccacg tgcaattgaa
    10201 agtggtgaat tgaaaatcga tgttgcattt ctaggagtac caacatctga tgattatgga
    10261 aatgctaatg cgactgttgg aaaatccgtt tttggttcat tagggtatgc aaaagtagat
    10321 gcacaatatg cagataaagt cattcttcta actgatcatt tagttcctta ccctaatacg
    10381 cccattagta ttccgcaaac acaagtcgac tatgtcgtgg aagtagaagc aattggtgat
    10441 ccgaataaaa tcggtgctgg tgctacacgg tttactaaaa acccaaaaga attaaaaatt
    10501 gctgaaatgg tcaaagatgt cattgttcac tcaccttatt tcaaagatgg cttttctttt
    10561 caaacaggaa cgggtggtgc agctttagca gtaacgcgtt acttagctag tgaaatggaa
    10621 gaaaaacaga tcaaagcttc ttttgcatta ggtggcatca ctaaaccaac ggttgattta
    10681 ttggaaaaag gtcttgttga aaaagtgtta gatgtccaag actttgacaa aggagcagct
    10741 gaaggaatgg cgcggcttga gaaccaacag gagatcgatg cttcctttta tgctgatcca
    10801 agtaataaag gagcggttgt taaccaatta gatgtcgcta ttttatctgc attagaaatt
    10861 gacacaaact tcaatgtaaa tgttatgact ggttcagatg gtgtgctaag aggtgcgatt
    10921 ggtggacatc aagatgcagc aacggctaaa cttactatca tctcagcgcc gttagtacgt
    10981 ggccgaatac ctacagtagt aaatgatgtt actacattga tcacaccagg gaaaagtatc
    11041 gatgtattag tcacagaagt aggggttgct atcaatcccc aacgtaaaga tctaatagct
    11101 atttttgaaa gaattccaca aattcctgtt tttacaatag aagaattaca gcaaaaagca
    11161 gaaaaaatag taggcatccc ggaacctttg caattcacag atcggatagt tgcctatgta
    11221 gaataccgag atggttcaat tttagatgtc gttcgtcagg tgaaagaatt tgaagaagag
    11281 agatcatgat gtttgatact ggagaaattc aagaaatcga ggatattttg atccataaag
    11341 aacaacgtgc taacttgcaa agcaacctgc tttccaagta ttcaaatagt tcattgatgg
    11401 tctttacatt gaatattcct gggccgatca aaaataatcc aatgattgag caggtatttc
    11461 gtcagggaca gcagtcaatt cagcaaatgt ttttaaaaaa aaaggtggaa atgacgtaca
    11521 caaaagaaat caatttgcca agtggattgg actggtacgt aatagtaaca gaagcacctt
    11581 tgaatctcaa aaaatggttg gtcacgttag aagagcaaga cgcattaggt agactttttg
    11641 atttagatgt cttgttcaaa aaaggagagc agataacaat tgtcagtcgc caagctctta
    11701 atcatgggga acgtccttgt tttatttgtg ggaaatcagc aaaggtatgt gcacgtaatc
    11761 gtacacatac tgtgaaagaa atgcaaaaga aaatcgaaca aatagtagcc gattccttaa
    11821 aaggagcatt gaaacatgca tgataatatt caaaaaatag cacaagaagc acaattagcg
    11881 atgctttatg aagttacatg tatcaataaa ccaggattgg ttgatccagt agaccccggg
    11941 tctcatcaag atatggacat ttttactttt ctacaaagta gtgtagtttt gactccctat
    12001 tttgaagaat ttatccaaac aggattggac cgacaacatc aaccaattga agaaaccttt
    12061 atggcgattc gacagattgg tttagaggct gaaactgcga tgttctcagt gacaaatggt
    12121 ataaatacac ataaaggtgc tatcttttca ttggggattt ttcttgctat ttgtggccgg
    12181 ttaactattt ggaaagttcc ttgtaaaaaa agtttctttc aaaaagaaat tcaaaaaatg
    12241 acgaaaaatc tacttaacga ttttgggaag attgatcaaa caaaaccaaa agcatggact
    12301 tggggagaat atctatttgt taaccatgga ttgacaggga tacgagggga agccaaaaga
    12361 ggttatcctt gtgtttttga ccgaggattg ccttattatc aagcatatca agggtcgcaa
    12421 caagataaga tgatagacac tttacttttt ctatcaatgg aagtagaaga taccaatttg
    12481 atcaaacgaa gtaataatag acatgttttt gaagagtatc aattacttat tcgtccttat
    12541 tttgaattag ggggtgtaaa aaccatacaa ggtaaaaaat atttggatta cctaaatcag
    12601 caatttaaaa agaaaaattg gagtattggt ggaagtgcag acttattgat ccttacaatc
    12661 tttttagata aaatcatgga caaaggatgg ttatgttgat actataatac attattttgt
    12721 attagtaagc taataactaa aaaatggttc aatacaaata ttttataaaa aatggtagtg
    12781 cctatccttt cagattgtag acaaagaaaa atttctttgt ctacaatttt tttgttaatg
    12841 acttcagtca gtttcgtgcg caaagcgtgc gaaacaagaa aaccatgcgt ttctacacgt
    12901 ggaagaacta gcatatcgaa aggagttttt tcatgtcaaa tgacgataaa agtttagccc
    12961 atactcgttg gaattttaag tatcatattg tatttacacc aaaatatcga cgaaaagtaa
    13021 tctataggca attacgaaaa gatattggaa aaatacttag gaagttgtgc aaaataaaaa
    13081 acgtggaaat tatagaagca catgcaacgc cagatcatat tcacatgctt gttcaagtac
    13141 catcaaaaat aagtatatcc agttttatag ttatctgaaa gatcgtagtg ctgtgctaat
    13201 ccacgagcag cacgtaaatc acaaatatag atacggaaat aaatcatttt ggtcggagga
    13261 atattatgtg agtacagtcg aattgaatca aaagacaatt gaaaaataca tccgtgaaca
    13321 agaagctgat gatcgcattt gagatagtat aagtaaaaga gagtagatgt tgcaataaca
    13381 aaagggtaaa aatggactac ctccagtaaa ataccgaaaa atagtttaac ttttggagat
    13441 aagtccattt aagggtctat agaatgacaa tttttttagg ggattttact attattactt
    13501 caagacccgc ttggattcgc aaagtgagtg aactcttaaa actacctgat agtaggttgt
    13561 tttaagagtt atctgaaagt aaaaattgca tttatatttt tgataaatac gtaaatttat
    13621 atatacgtat ttatcaaagt tttaggccaa aggaatattg tgtaaataca ctaggattga
    13681 atgaatagac cagaagaaat tgcgtccaag aacaaaagaa gcatgatagt gctctatata
    13741 aattgggcat tcaagaatct gaaatttaaa ggtagaattt tagttagact tttagatttt
    13801 aaacacaaaa ataaccatac aagcaacaag aagcaaagtg ctatattata aattgtccgt
    13861 ccgtttactt acataagatc attggggcta tttttaaaag agaataatag ataataaatg
    13921 aaaaaaaagt caagtccaca atcctgtgta aaatactata caatgctctc actatttttt
    13981 acttggcaaa tttaatatat tttcttgatg aagaaagcca ctcatcgtgt tgatcaataa
    14041 ggactgctcc aattaaacga ttggctgaaa cgcagtttgg aaagatacga ataatttttt
    14101 ctcttctgcg cacttcttga ttcagtcgtt caattagatt ggtactcttt agtcgattgt
    14161 gggaatttcc ttgtacggta tattgaaagg cgtcttcgaa tccatcatcc aatgatgcgc
    14221 aagcttttga atattttggt tgatcgatat aatcatgaat caatcgattt ttagcctcac
    14281 gagctaagtt aatatctgtg aacttaaaaa ttcctttaac agcttctctg aaagattttg
    14341 aatttttttt aggaatggtg gtaaagatat ttcttaggaa gtgaacttgg catctttgcc
    14401 aacttgcgtt ggtgaaggat tttctaatgg cagagactaa tcctttgtgc gcatcagaaa
    14461 taacgagttc tgtaccttgt aaaccgcgtt cttttaggta ttcaaaaaat gttatccagg
    14521 tctcttcgct ttcgccactt tgaatcatga agccgataat ttcacggtcg ccatctttgg
    14581 ttattccaat cgctatatga cagctttttg agagtactcg attttcttct cgtactttta
    14641 tatagagtac atcggtcatt aagtaaggat aatttttttc tgataataaa cgattctgcc
    14701 actcgttaac cattggttct agctgttctg ttaagctaga aacgaaggac ttagagacgg
    14761 atttaccaca aagttcttcc acaatttttg atactttacg agttgaaacg cctgatacat
    14821 acatttccaa cattgaagca atgagggctt tttcgtttcg ttgataacgt tcaaacactg
    14881 tgggtgaaaa atggccatca cgtgttctgg gtacttttaa ttctagcgtg cctatacgtg
    14941 tcgtaaagct gcgctcataa tagccatttc gttgactttg tcggttttct gttcgttcat
    15001 attcttttgc ttgaatatat tctgttcgtt gattttccat tagttgatta aataccgttg
    15061 ttaaaatatt tttagaaacg tcatccttta cagaatattc aataatgctt tgaatctctt
    15121 cgcttttcag tgtaaaatgt acttgggtca tgtaaaagtc ctcctgggta tgtttttgtc
    15181 gttaaaaaca ttgtaccgta aaaggactgt tacatggcct ttttactttt acacaattat
    15241 aaggacttta tcgaaaaaaa gcagttattt gttaaaatca ttgatattat taataataag
    15301 tattttttga aaggggaaat ataaaaggtt tttgaaaata aataaaaaat agtattactt
    15361 gttctattgc tagttattgc tagtctttat tcttttttgt tttttaggga tgtacaaaag
    15421 atctcaacca caggagacat tgcttttcac ttttctagaa taaaatgctt gtcctcagta
    15481 ttttctggtc caataaattt taccacattt aatagctatg gcggaggcgt gaattttttt
    15541 atccatatct aacatctttc cagccgtaat attttactgg acaacaaaca atttgattct
    15601 aagttatata cttactatac gttgggatac tgaatatctg tacaattcta gtgagctatc
    15661 aatatggaca aaagaataga tgcagccttc ttattcagct gtttgtatag cttttatgga
    15721 ttgatatata ttagcgtact gcaatttcag aatcaattgc gttgacgatt gtaccagttg
    15781 tcttgtatta cacatatact cttctttatg aaagaaaaaa ctgcgtgatt cttttagctg
    15841 tcagtatgag tttgctcatc tatacccata ttctctccac ctttatgagt gtgattgtta
    15901 ttggcttctt gtttatcggc tctcttttct ctaagcggaa agagagaaaa gaaatgtcga
    15961 atctgatatc aaatatgata aaagctgttg gttggaccat tcttttaaca gcttacgttt
    16021 ggtatccgat gttacaacaa gtcctacatc aaaaaattaa tcgtcctttt cgcacaaaac
    16081 ttcaagaaag ggcattaaac atttctgata gtttaatcgg tgcagtaaat aatgatttag
    16141 ttacatttac aatgggaaca attggtgtgg tttcatttat tcttccactt ttctttaaaa
    16201 aaaaatttgc caataaagaa aagattatta atttttgtgc agtgaccact tggttcttat
    16261 caacgaatct ttttccatgg gaatttttac aaaaaacacc tattcaaatc attcagtttc
    16321 cttggagaat cttgggtttt caagtgcttt ttggttcatt gatcttaatt atagtgtttt
    16381 taaagtggaa aacaagcaac aaaaaaagta tgtgtagcct tgtaggaata gtccttctta
    16441 tttttacagt gactgtagca acagaagcga attattcgca gaaaattcaa tcgtataaag
    16501 gtcgtttaat tatgaccaaa aaagatgtta cactttatac aacctcgaga actggaggtc
    16561 tttatgacta tgcaccatta gatgcattga aatataaaga tcatttaaag aaacatgaag
    16621 taaaagtcta tgattgatgg gagaatgcat ctcataaagc acataattct aaaataatct
    16681 atacagtagg agatgcgaat gagcaaaata tcacgttacc tgtatttaat tactgggaac
    16741 agttatgaaa gtaaatggga aaaagagcac tatagaaaat gacaatggtt tagtgtctat
    16801 taaaggtacg ggaaaaagaa ctatagttga ggtttcatct acgtatccaa ctacgatgat
    16861 tctatcttta ttaattagtt caataacttt tatattctta tttacacgtt atttaataag
    16921 atgctgcggt taaatgaaaa tagattagat agatattata aatatgttga ttctattttc
    16981 atagcaatgg agaaaataca ttagcaatat ataaaagaag gtatcaagag tcacggtgaa
    17041 tttattccga aaagtgaaaa gaacaaatat aaaatttaat aaaaatatag aactaaatag
//
LOCUS       DARPZJ010000050        16903 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.052, whole genome shotgun sequence.
ACCESSION   DARPZJ010000050 DARPZJ010000000
VERSION     DARPZJ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.052"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..189)
                     /locus_tag="SLE23_002081"
     CDS             complement(<1..189)
                     /locus_tag="SLE23_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468965.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(199..1014)
                     /locus_tag="SLE23_002082"
     CDS             complement(199..1014)
                     /locus_tag="SLE23_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEI8468966.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1276..1719)
                     /locus_tag="SLE23_002083"
     CDS             complement(1276..1719)
                     /locus_tag="SLE23_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HEI8468967.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1853..2191)
                     /locus_tag="SLE23_002084"
     CDS             complement(1853..2191)
                     /locus_tag="SLE23_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8468968.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2179..2556)
                     /locus_tag="SLE23_002085"
     CDS             complement(2179..2556)
                     /locus_tag="SLE23_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEI8468969.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2780..3973
                     /locus_tag="SLE23_002086"
     CDS             2780..3973
                     /locus_tag="SLE23_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8468970.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4139..4561)
                     /locus_tag="SLE23_002087"
     CDS             complement(4139..4561)
                     /locus_tag="SLE23_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468971.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4956..5150
                     /locus_tag="SLE23_002088"
     CDS             4956..5150
                     /locus_tag="SLE23_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468972.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5147..5641
                     /locus_tag="SLE23_002089"
     CDS             5147..5641
                     /locus_tag="SLE23_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468973.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5803..6975)
                     /locus_tag="SLE23_002090"
     CDS             complement(5803..6975)
                     /locus_tag="SLE23_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEI8468974.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7181..7996)
                     /locus_tag="SLE23_002091"
     CDS             complement(7181..7996)
                     /locus_tag="SLE23_002091"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEI8468975.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8146..8592)
                     /locus_tag="SLE23_002092"
     CDS             complement(8146..8592)
                     /locus_tag="SLE23_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEI8468976.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8589..9593)
                     /locus_tag="SLE23_002093"
     CDS             complement(8589..9593)
                     /locus_tag="SLE23_002093"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEI8468977.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9633..9962)
                     /locus_tag="SLE23_002094"
     CDS             complement(9633..9962)
                     /locus_tag="SLE23_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEI8468978.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10088..12415)
                     /locus_tag="SLE23_002095"
     CDS             complement(10088..12415)
                     /locus_tag="SLE23_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8468979.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(13258..13551)
                     /locus_tag="SLE23_002096"
     CDS             complement(13258..13551)
                     /locus_tag="SLE23_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HEI8468980.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(13954..15132)
                     /locus_tag="SLE23_002097"
     CDS             complement(13954..15132)
                     /locus_tag="SLE23_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8468981.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(15236..15550)
                     /locus_tag="SLE23_002098"
     CDS             complement(15236..15550)
                     /locus_tag="SLE23_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468982.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            15657..15872
                     /locus_tag="SLE23_002099"
     CDS             15657..15872
                     /locus_tag="SLE23_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468983.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(16172..16414)
                     /locus_tag="SLE23_002100"
     CDS             complement(16172..16414)
                     /locus_tag="SLE23_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8468984.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(16401..16829)
                     /locus_tag="SLE23_002101"
     CDS             complement(16401..16829)
                     /locus_tag="SLE23_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8468985.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         4927 a         3271 c         2936 g         5769 t
ORIGIN      
        1 gcaacctgga ccaataaaaa gtaaagaaaa aataaaggaa aagacattcc ttccatctat
       61 cgacaaaagg aacgcagctg ctatatacaa gatattgaca caccaaaaac aaaggctact
      121 tgccaatgat tgatacaacc aataaaagaa ttccatataa acatttttgt caaaacgctg
      181 ctctttcata atcacctcct attccttcat tcctgatgaa gcgatccctt ctacaaaata
      241 tttttgcatc gctaaaaata taaaagcaac aggaagaaca gaaacaactg aggcagccat
      301 gattaatgcg tactctgcat caaatagccc aataaacatt ttcaacccta actggattgt
      361 tttattttcc gtagaagaca aataaatgaa tggccccata taatcgttcc atgtattaac
      421 gaatgtgatg atcgtcaaac tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg
      481 atagattccc cactctgata agccatcgat ccgcgcactc tcacataaag aatctgggat
      541 actactgtag tattgcttca acaagaacac accaaaagca ttgaacgctt gtaatagcac
      601 caacgaccac aacgtatatg ttaaacccac ttttctcatc ataatgaact gcgggatcat
      661 ataagactgc caagggacag caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc
      721 tttaaaattt agtttagaaa acccgtaagc agcaaaacta gaagtaaaca actgaatcaa
      781 cgtgatcaca acgcttaaaa aagctgtatt cttaaaaaat gtcactaaag gaatacgaga
      841 ccaaataacc agataattct ctaaatgcca agttttaggg atccattgaa tcggaatcgt
      901 gaacacttca ttatttgctt tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt
      961 caataaagct aatacaatca gcagaatcat acccaaccat tgaataaagg gcatgttttt
     1021 tgaacgaatt tttgcttttt ttctttcatt tcgaacacct ccaaagttat aatcttcatt
     1081 tctttgtaat gattacaatc cagaacaacg gttattatag ctgattcatt tccgttcttc
     1141 ttatgtttgt aagcgcttat ttaacaagtt atgtaaatct ctttattttt tttgatttaa
     1201 aaatgaaaaa atacaaaagc aagactgtca tacgtctcgc ttttgtattg aaatttcttc
     1261 gattagagat acttattact gttcaaaagc ttctttgaaa cggtgaatca attcattgac
     1321 tacaggtgat aaaatccgat tctttttcca gactagcatg cagttcgttt caatcattgg
     1381 gtcaagcgga acgaatgtca ctcgctttga aagatgactt acagcacctt ctatgactaa
     1441 agcagcacct acctgattct caattagcgc aaatacattg aaaatcaaat tgtacgttcc
     1501 tgtgatcagc aactgctcct tttttatgcc taaccagtca gcaaacattc gctgtatttc
     1561 tggacgcttt gagatcaaaa gaggtacatt cgcaaagtct tcttttgtta tcacgtcttt
     1621 ttttgctaaa acagaatttt ctaaaatgag caatccccat ttttcctttc ttggtaacaa
     1681 aatcgtttcg tatttctctg tatctactgg atctagcaaa atcgctaaat ctaacaggct
     1741 tttttctagt cactccgtga tatcatcact tgttccgctg tggatatgaa attgaacgct
     1801 gggataatca cggatcaact tttctagtaa tagtgccaat gtattcgaat tatcagcttc
     1861 cacacagccg atcgtaaatc ggccgctgaa taattgtttt tttctgttct cgaattcttg
     1921 agtggtttga ttcgttaaat ctaaaatttc ttctgctcgg cttttttaga aaataacctg
     1981 cttctgtcaa gatcattttg cggttttcgc gtacaaacag ttctgttcct agttcctctt
     2041 ctaactcctt cagttgtcgg cttaaggttg gttgtgtaag atgtagaact tctgcggctt
     2101 gagagattgt tccttcttct gcaattgtcc aaaaatattt tagtaagcgt aactccatag
     2161 cgatgctcct tgattttttt acttgataca ttccatttta tttctagata acacacgatc
     2221 atatttcttg atttttcctt gtaaacgttc caaacactct tgcatttcag caatttcttt
     2281 cgtcaaaagt tcactttctt caatcaaaag cttacgccgc tcaaatacag ttgcttctcc
     2341 ttcgctagat aggcgaatat attcaatcaa agactcgatc gataatccgg catttcgcat
     2401 acagatcgta aagtcgaccc attttaggtc ttcttctgta taatcacgga ttccgccttt
     2461 tgtccgatta actggtggaa tcaacccgat tcgttcataa tagcgcaatg tatcggccga
     2521 aatgcccttt tcttcactga cttgtttgat attcatctga tcactctttc tcttaatttc
     2581 ttgccacttt acttatgtat tttatttatt ctacaacttt aagtgtactc caagtcaata
     2641 ctcatttcta ttaaaactaa gctggattat ctatatcggt tgtttgtgta ttatttcaaa
     2701 taaaaaagtc ttgttttttt attctttttt ggatatactt ttaacaattt agggaaattt
     2761 taggaaaagg ggtataaaaa tgacaacgta tcagcgaaag gtattattat cgacatcggc
     2821 gggaattgct ttagagaata tggatattat gtttttagct ttttcattat cttcaatgat
     2881 tacttctttt catattagtg gtacgcaagc gggtttcatt tcaacgatca ctaatttggg
     2941 gatgctcatt ggaggtattt tttttggcat catagctgat aaatatggac gtgtgaaagt
     3001 attttctcaa acggtccttc tgttttcgat tgcttcttta ttgatgtatt ttgcttcaaa
     3061 catctacttg gtttatctct ttcgctttat cgcaggtgta ggagcgggag gagaatacgg
     3121 ggcgtgtatg tccttgattt ccgaaagttt ttcaaaaaaa caaattggac gagcttcttc
     3181 ggttgctggt attggtgcgc aggtcggtgc ggctttggct gcgattttag ctgctgtgat
     3241 cattccaacg tttggttgga agatgttgta tgtcgtaggt gtactgccgg tgttgatggt
     3301 cttgttcatt cgtcgcggct tgactgaacc aaaggaattc aaatctgtac aatctgccga
     3361 aaagaaaacc aaacttagca gactgtttga atcaaaacat cttgcttggc aaacatgtgg
     3421 ccttagtatc atggtaactg tccaaattgc cggctatttt gggttaatga attggctgcc
     3481 ttcaattatg caaaatcgat tagggctttc ggtttctggg tcttcattgt ggatggtcag
     3541 tactatttta ggcatgtctt tggggatgat gacttttggc ataatcatgg ataaattggg
     3601 gcctaaacta gccttttctt tgtttttaat ttgttcatcc ttatctgtct atctacttgt
     3661 gttagcccat agccagtgga gtttggtagc agccgctgtg atagtcggct actttatcaa
     3721 tggcatgtat ggtggatatg gcgcagtgat tagtagtttg tatccaacag aaatccgcgc
     3781 gacggcgaat aatttcatta tgaaccttgg acgagctgtt ggtggttttt cttctatcgt
     3841 catcggtttc ttgatggatc attatagttt aactgccgta atcttgtttt tgagcggtat
     3901 ttacctagtc agtctgctgg tcttgacaac tcttactggt gttacagcat taagggaaag
     3961 cttgcagcat tgatagttga gtctgtaaat gacaagaaag aggtgtggca aaagcttgca
     4021 tctgcggtaa taagaccagc caaatcaaaa acatgagaca ctgtttccgt ttggctggtc
     4081 gtattacttg atgcagggca gctttttcaa ctgctaattt ccttctatct ggcggcgact
     4141 attctttgac gtccgtcatt tcaaagtact ttactaataa cttagcataa cgaaaaactg
     4201 tggatacact cgtatattga gcgtctgcat aatcttccaa atttttctca ggatgttgat
     4261 acatgaattc aatcaaatga taattatatg attttctgta gaaatgaaga taaataatgt
     4321 agattgggaa gttctcctgc ttttccatag aaaagcgccg attattctca ttcttcaaaa
     4381 tgaccttatc aggatatttt tggaacaatt cttctaaatc tgttagataa ttcaagatag
     4441 acttacttga taccttcaat tcgttttgta gttcttctat tgaacaccaa cgttctgttt
     4501 caagcagtaa atgaatcatt ttaattttct tttgagaaac ttttgttaaa aaagtctgca
     4561 tattttctcc tcctgtatct actttactat actacataca agaaaaaaaa cggatacaaa
     4621 tatcatattg tcacaccgtc aatagtgcat aaacctgtta ttatttctct ttttttccta
     4681 agtattctat tgatatgaat catttaatcg tttattatat aaatgtcaat aatctaataa
     4741 taaaataacg tacatatttt attattgcat acttaataac agaactatag caaaaaatcc
     4801 cgtgtatcaa cacgggatta gattaagttt cctcaatcac tattcataac acaattatta
     4861 taacaagtaa gtaaacaatt gaaaaggaca tttattgaaa acggttgttt tttacttaag
     4921 gaggaaattt agcgaaaaaa ttagttgcat tgtttttggt cgcaggaagt ttgttgagtg
     4981 ggtgtggtgc tactacgtct actactcaaa gcacaagttc agatcaggct tccagcagca
     5041 gtaccacgat ctccgaaagt acggcagatt catcgaaaga acaagaacaa attgaaaaga
     5101 aaaaagaaga gaaacaaaaa gcggaaaaag ctgcactaga aaaaaagtga cagaagcgga
     5161 atctgctttg tcacaagctg aagcaaatcc tacaaaagaa aactatgcaa ctgcttcagc
     5221 agctatccaa gcgctacctg aaaacaaaca agagttgaca agccgtcttg ctgcaattga
     5281 ttccacaatc aaagcaaaag aagcagaaga agaacggaaa aagcaagaag aaattgcacg
     5341 acaacaagca gaacaagcgc aacaagaagc aatcgcacag caacaagcag aacaggcgag
     5401 gcaagaagca atcgcacagc aacaagcaga acaggcgcga cagcaatcag cagctgaaca
     5461 ggcctctcag caggcacaag ccgcagctcc tgagcaaaat aatgaacaaa ctgtctatgt
     5521 cacaccgacc ggttcaaaat accatacaca taaatgtgga aatggtacgt atacccctgc
     5581 cactttaagc gaagctcaag ctcgtggttt aaccccttgc tccaaatgtt atggaaacta
     5641 attcaaaagt tatactataa taataaaatt cttctgaaac ataaaaaaat agaagatggc
     5701 gttccagata gtaaaccaaa aataacagtt tacacgtcca tttcgtcagc ttctctcttt
     5761 tttcatttag tctgttccct ctgctttttt ggacatcttc attcattctt tctcaatcaa
     5821 atagtacacc tctttttctt ttcgcagttt atatcttcct tttttcaatt tcattgaaaa
     5881 ctgtttcgaa tgtttatgtt ttacatggat tttaagcagg agctcctcat gttgcaagcg
     5941 atagttcctg ccttttaaat cagaaaatct cactagtccg tattcatcag aagctttcac
     6001 aaatggaact ttttctctag taatatagtg tttgccgttg agcgttttta cagaaaagac
     6061 cattccttcg attggtcgtc cgtttgtgtt ctttacataa aaagataaag gatagtttcg
     6121 cttagcgatg gccaaagaat ctaaataagc gatgagtagc caaactaagc cgattgatcc
     6181 aagtagtata ccgataaacc aaataaaaaa tttccatttt ttccattgat caattccttg
     6241 gatcgctttt tttgcctctt ttgcttgata aggaatacga tgccccgtca caagcagtcg
     6301 atgtgtattg accatataag gagtacaggt aagcaaagtc acgagatctc tgcctttttg
     6361 gatacccaaa gaatctactt catcaggtaa gaccacttgg attttttcta cttgatacgc
     6421 caatgtcttt ccattgatct ggatgaaaaa ctggtctcct tttttcaact taggcaaatc
     6481 tgtaaataat tttgcttctg ggagtccacg atgcccagaa agaacggcat gggtgttttt
     6541 cccgccagtc ggataagaac tttcttccaa taatgacgtt cctttttgca aaaatatttc
     6601 cgttgtctga tcgaatatag gtaagctgac attgattttt gggatttcga tgactccaag
     6661 catatgttcc ataaaaaagg cattactagg taaatctttt aatgcttttg catcaactgc
     6721 ttggttgaaa ctgcctatcc ctggtgatac gttttgctct gccaactgtt ggtttttctt
     6781 tgtcattttt tcctgctgtt tttttatttc ctctgaattc ttattcgatg cttgcttttg
     6841 ataatggatg atcatttgct gggcaagaaa atcattcagt gaatcttcta caaaaggata
     6901 agaaaagatc ccgatcccaa cgactaaaat gattgccatg aagatgtcca gtattcttat
     6961 tctgctttta ttcatcatgt ccacctattt tctaatatgt atatgaagag gttgtgaaat
     7021 cagcgccttg acctgagtat tagcgaagca aacggcaaaa tagttcctcc tattttgccg
     7081 tttgttgagc gaataccaag agaccgacca cttgtcacaa cctttctccc catttgaatc
     7141 actatcgttt atttatcgta tgatttttgt ttccaatagt ttaagcttct gtttcttgat
     7201 ggcgtttttt gaaatagatc actgctcctc caactaaagc agtacctacc aagatgaata
     7261 cgatgatccc cataccacca gttgaaggca agattccttt aggttggtta tcgatcgttg
     7321 tttcatcaga agttgttgga tcatcatcta ctgtaaattc agtgtacgca gcttcattct
     7381 taggtaatgc gtagccttct ggtgcttttg tttcttgaag gcagtatgcc ccttgtttca
     7441 gcccttcgat tgaaaatttc ccttctgaat cagaaatcaa tttcacttct tcccagtcag
     7501 aacctgtgac ttcatctgac caagcatatg ggtattctcc tgaggcaagg tttgctattt
     7561 ttttcattaa tttaacagtt ggatcttttg ctcttagaat agaaaattct gcatcggcta
     7621 atttttcttg cgtgttcaca tcttgtttga tgaagtggaa atcaccgtag ttttggacat
     7681 tttctacagt aatcatgtta tccgtagttg tattttcccg attgactaca ccgtttggat
     7741 tcccaagatt ggcttcatct gcgccatgga tgataccggt tgtttgttgc aattttccgt
     7801 tttttactat aaaagtagtt tctttttgtg gattggttaa ttgataacca tctggtgctt
     7861 ttgtttcaac taaagtataa ttgccgtcta ttaatccatt gacactgatg gatccttcag
     7921 tatcagttgt gaatgtcaac gctgactcag caggatcata gagagcgaca ccagtgtttt
     7981 catcaaaacc ggtcacgaat tgattctctg aatttttgat ctggaattgc gcccctgcta
     8041 acttatctac ccctgaaaag ttcccagctt tctggatttt gatattgctt tctttgatga
     8101 catttttagc atataggtga atcgtgtcta aaggtttgtc agggtctagg gtaagcttaa
     8161 cacgatattt ggcgacgttt cgacaccggg ctttggtgtt tctacaaaga cgtatacagc
     8221 atctttccca tcagatttac ctggaagagt caggttagct aatccttcac cagaagtcgt
     8281 tacacttgcg aagggtgtag cgtctgctgg aactgctgtg tctttacttg gatagtacgt
     8341 agcagtgatg tcatatacgt tgaattcaac gccgttcaac ggttcgctat tcggaaatgt
     8401 caattccgtt ccgttgttta tttgattttc tggtgctgaa gtgaatttca atttatgcaa
     8461 attaaccgta acattttctg gtgtaggtga tacggctgca gaaacctctg cagttcctag
     8521 gccgagaacg aaaggaagca gcatgatagc agttcctaaa aacgtccata tttttgtttt
     8581 gatgtttttc attttatttc cctcctattg tttccttttt gttgtttttt ataaaaccaa
     8641 gctgtccctg ttgaaaggac tagcaataac cctaaaattg agaaacctcc aagcatctct
     8701 tcgcttgttt ttggaaagct tcctccattt ttttcatttg atggaccatt tgtctgcatc
     8761 tgaactggcg tttttccatt attcgtcgga tttgcttttg gttcgttgat gatttccaat
     8821 ggtataggat gaagcggatc ataactgcct ttttcaactt caaagagaat ggttgattga
     8881 ctcaatatat atcctttagg cggtttaatc tccactagtt cgtaacttcc aaaagacaat
     8941 ccatggacag aaaatgttcc atctttactg gaagtaaaaa tcgttgctct tgaatcatct
     9001 ttggctaccc aatgatttat cccgttttct tgcgctaagt attggtcatt ttttttgact
     9061 agaaattgag catctgctag tttttgtttc gtttgccgat ccactttgac aaattgtttg
     9121 cctcctgttt ggatggcaag atgtgtttct actgtttgat tgtcagtcgt caaacgtaca
     9181 tcgttatcaa atgtcgtttt ttcactgttt tctttcaatg tcatttggta acggatcgtt
     9241 aatttttttc cagcaaacga actaagatct tttccagaat ctgataagac aaaaccatgt
     9301 tttatttttt gtgtgtgaaa tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt
     9361 tctggttcta gccataactg aggatcagct gtatctttga tcgtataggt tcctatctcg
     9421 ttgatgttct caggaattgt tacggtgatg agataaggga ctttatcccc atctgcaaaa
     9481 tctgtctgct tattctctac tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg
     9541 ctctttggat acaagtggat ggtcgtcaat ttatgattag atgaatctgt cacaggaagc
     9601 acaacgacaa atggtgctga tttttctttt acttaatctg aagtctttat ttccgtaaat
     9661 cggtaaacag cgtcacgacc ttgctcatct ttgtccgatg cactaaaaga agcaatgccc
     9721 tcttcctcgt ctactgtttt tgtcacattt tctgccagta ttttttcact atcacttttt
     9781 tgtgctagtt ttctttgtgc gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat
     9841 tcatccgaga catcatatat agcgaaagta acgccgttca acccttttac tccttgaaag
     9901 ttatccggga tatttattcc gtcgttttga ctgatacttg gcatcttatc gctttcgaac
     9961 attcgattat gcaaagtaaa tgtaataggt gattctctag ctgacacagt cggagaacct
    10021 ataaaaaaga ccagtaggat aaaaaagaga acagcaaata tatccacacg tacatttttt
    10081 gtttttttca tcgctgttca cctgcttttt tcttacgatg gataaaataa aagaagccag
    10141 aaaaaataaa gatcagtcct aaaaagacaa agggcagtag acctatccca cctgtcgaag
    10201 gaagcaagag agtcggattg atcgtcaact tagcggtatc tgttgcgata atcgtataat
    10261 tattgtttac acttccttcg cctaaactaa tcgttactat ttgtgatcca atatctgtcc
    10321 ggctgttaac tgttagggta taatccaatg attcgcctaa gacaacaccg gtaacgtgga
    10381 gatttccaac cgaaatcgag tgactttggg catcataatt aaaggcagcg tcatcgacag
    10441 taatcactgc gttagcttta tagatggtat aagttcctga tgtgttggct atatcagtaa
    10501 atgacaactt gggatttgct gctttgactt tgtctattcc gctattcgtt agtttaattg
    10561 tatagctgcc agcattaacc atattttttg ctgattgtgc atctgctgtg taatccatac
    10621 tgctaagtgc cacttgtact ggagtaagcg aactagtgac accctctgct agcttgacat
    10681 ggattgacgg gacacctgct tttccatcat atgtcttact gccactgagc tctaccgcac
    10741 cgctgatttg cttaatcgta tagacatcag atgtctgcac gatagtaaat aaatagtttg
    10801 ttctggcagc tagtttagct agtccgcttt ttgtcaattg ccaagacgta taggttccaa
    10861 tttcagtagg cgcagttact tcaactccct tttcattcat cgctttgaaa tcagttggat
    10921 tccatgtgat ttgatcaata ctgagatcat tgtttaaaag ggatgttgat tctgttttat
    10981 cattaaaggc atatttaacg atcggtacaa cagaaagacc atcatagtac ttactgccat
    11041 ttgcattgat tgatactgtt gcatttgtct tataatatag gatgacttca gaaatctgtt
    11101 ttccatttgc gtcctttacg attacatttc catttgtatc taaactagct aaaacactca
    11161 ttgctgattg gttctttgtt tctatcgctg aaacagctgt aaaggtatat ccgttgatag
    11221 taggcgtatt agtcgtcagg tcttgtgcag cacttccgta agtaagattc attattttag
    11281 aaggagcaat catctgtcca aaatagtctt gatacttaat agtgattggt gtttgtttgc
    11341 ctgtataggt caccgtatcg acgttacttt ctagggctgt gaaagaaccg tttgtttgtg
    11401 caaaagaata gcccgttact gctgttggag tgataaccac tttgtcaccc acatggattc
    11461 cagataatgt agtcccgtac gttccgattt ttgctgctcc accattgact gtataagaaa
    11521 aagttcctgt ccgattcgca ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg
    11581 aaacatttcc cttaccatca acgatctgcc catttttgat cgagtacccc gtgaatggaa
    11641 tatcatttgc taactgtata ccgattgaaa aagtactcat acctcctccg gcaggaagcc
    11701 ctccccatgt tgagggtgta aaagaataac ttttatccgc attgggtgta actgaatcga
    11761 tcgtatttcc agcggtagcc acccccatat agatactttt tgggaatgtg atagtagtac
    11821 catttactgt ggagccaata aacagattat ggatatctgg acggttatca ataaaagcga
    11881 ttgctttggt tacgccttgt aacgcagttt tatccgcact catcgatccg ttaaccgcaa
    11941 caatgactcc atctttggca tatatcactg tatatccatc tggtatggta tgtccgttga
    12001 aattcgcagt ggccgcaaca gtactaaatg tctggcttct acctgtttct gaataagctt
    12061 tctcccctgc tgcttttgct gctgtgattt ctttttctgt cggatcaatc agttgagtcg
    12121 aggatgtggt tgaggttgtc tcgttgttgc tagactgatt ggtgctttct atggactgta
    12181 tttcagaata gggtggacta tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt
    12241 ctgtataaac gtttacataa atacttgata agctccctaa gaaagtaaaa atcaagatga
    12301 tcgaaatcat aatgggatgt aagtattttc ttttagatac agctttgagt ctagaaacaa
    12361 aatgtttttg acatatacgt tggattttat tttgagtttt cttaatcatt ttcatccctc
    12421 ctctcaataa aaaatcatca aataatcctt tacacgttat tctaaattta atttttatta
    12481 ttttattgat gtatagaaag tttggggctt tttttctctt tttattctaa ggttatttta
    12541 gtcttgtcct ttaatacaaa gattttattt ttaaataaaa aatactcttt ttttacgatt
    12601 attgaaaaaa aaagataaaa cttgattaat tgaagtattg cttaaatttg gaagctatga
    12661 gggaagaata aaagagttag gacgggatta tctactattt ttctttgttt taaatatttg
    12721 ttatctttga acataaaaga gaaatgtgtc gactgcagtg ttgtgtccct catcacgaat
    12781 aaacggtgtt caattagctg atcttgtatt cacttaaaaa atggtaaagt acgagttgct
    12841 attccccatt ttcaattttc taacgctcag gacaaaatac tgttttcaca acctcattgg
    12901 aataaaagca tatatattgt ttcaagaacg aaatcttgtt atctttttaa agggcatctg
    12961 tccaaaatct aattttagga ggtacgtttt ggtatttatt cgtacaaata aaagagaatt
    13021 atctttattc atgtaacgca tccaattgat tttttcatgt acgctcctgg aacgatttta
    13081 ctgacgattg cttatttaac tgcgaatcgc tcattagctt ttatcatagc tatccatatt
    13141 ttgaataacg ttcttggctt tgtattatag atacagatga caaaaaaagt tcaagtatgc
    13201 ggtgtagaac caatatcgca tacttgaact tttttcaatg agtataaatt aaaacttcta
    13261 attttcaatt cccatcatct gatatgcccg accgtctgaa cttcttttga aaaagccaaa
    13321 tgtgattaga taacgtcttt gttcgacata atcgccacta gaaaatacgt tcagcagtat
    13381 cgaattaacc tctgtttctg tataagtcac tccatggtca aagcgtttca agacttcttt
    13441 caataggatg tatttctttt ttgttgaact tggtacttgt tttacttttc catcattcat
    13501 gaatgtgtct aaaactttca tcttttcttg ctccgtataa gtataaacca tcttctttct
    13561 ccttttgatt ctaagaatac tccatttatg ttagaatatt ctggattttt tattaaagcg
    13621 gttactctta agaaagatat tatcatagtg ctcttttttt tactactact tataggtaga
    13681 tttattctaa tccattattc tcccctacca ataattaaag aaaaaactgg atcagggtgt
    13741 tcaaattaca tgctaagaaa aaagaaccct tgaataccaa gggttctttc tcagtctgat
    13801 aacaatgatt aacgacggat ttctttgata cttgtgaaaa gtcgttaaag tattgatata
    13861 aaaggatttt tattacctct gactacatat tgactaattt gttaaaaaat cgtttttcaa
    13921 gaatcctgta ataccagtgc tttcaccgtt tttttaactc tctaaagaac taaaagcaat
    13981 cagaggtttt accttttcat ttgacgttaa gtggcgataa attttcgaag ttgtttggtc
    14041 agtatggcct aagcgatctt tcaagacttc ccagctacag tgttccgcta ctaagcttgc
    14101 cattgtatga cgagctaaat gagtatgaaa tggcttatta attcctgagc gattcacgca
    14161 ccgtttgacg tgatcattta catactctcg acgataagga acaccacgtt tactagaatc
    14221 aagatacaca aacaaatatg tttcttctat aataaacctg taatgttgcc tcatctcacc
    14281 caaagcctta atcaactgtt gtagcttttc cataactaga ggagttacta gaactcgtct
    14341 agcagaacta actgtcttag tagtttcaat tcgaaaatcc ttactcttac ctttaactgc
    14401 cgtttgctta tagaacagaa tttcatttct tttgaaatct atatctccag gctgtagagc
    14461 aagcgcctcg ctgactcggc agccagtgta aaatagaaca tggaaaagta cagacatcgg
    14521 taattcctca tgaacaatgc cataattcaa aaaagttctc aattcatcga cagtaagaaa
    14581 cttgtcctca atattattta tggcttcttt taaatcagtt accgttaact gatattttgg
    14641 cattctcaca gacttcattg gattttcact tatcaaattc tttctttgac aatatttaaa
    14701 aatcatattt agaacttgaa taagtgattg taaactattt ttggcatagc caacatttgt
    14761 tccattaacg ccacattcct ttaaggtaaa aagcaattct tgaaggcact ctggtgtcaa
    14821 atcagacaac tttttatcac caatccatcg aacaataatt tttaattgtt cctctcgctt
    14881 atcataggtt atttcctttt gttcatttaa cgaacggtaa tattggaacc attgctcacc
    14941 tacaacacta aacttgtcat tgcttgcaac aatttttttc ttaagccttt gttgtttctc
    15001 catttccaga taagcgagtt gcgcctcacg ttttgaatta aagccacgtc ttgttgttcg
    15061 atatgcttga aagtaccatg tgatcctacc agtagaactg atttgcttct tgaatcgatc
    15121 tgttttttcc atttattgat tcctcctatt ttgaaggaac ccaacaagca gaaacccttt
    15181 ggaaatcttt ctatctatgt catcattgta ccgcatctta gaaagaaaat gtaacttata
    15241 aagatcgaag tagtcgcaat ttttctcgat agtcattcga atcactcttt ctcatccatt
    15301 ctaaaacatc atcacgaaaa tagtgtcctc gaatcccgta ccaacaggga ggaaactcac
    15361 caagttttac taaacggttc agtgtactat cacttatctg aaatagtcgc tttaaatcag
    15421 tatttgttaa taccagaggt aaatgactga ctgcaagcaa tttttccgtg taatcttcca
    15481 gttttttttg taaaattgaa tagaactcta tttccagaga attaacattt gttttaactt
    15541 ccaactccat cacccttctc tctcaaaatc aaaacgacca ccacggtacc ccttaaaatt
    15601 gtaaaaaaac actccagtac tccatcaaaa cggactagaa aagaggaatt tttaatatga
    15661 aacaaggaat tgcagacata aaaataatta aagaaattct tgaaaaatct acggctaatg
    15721 caatagcatt cggaacagga atcaacttga gtacagtaaa aaaacttaaa agtggagaga
    15781 gagctgaaga aaaattaaat cttgccgatg ctattaaaat cacagaattt ggcatgaaaa
    15841 atatgccaac caaaatcgaa atatggaaat agtagttttt ctgatctatc agctgttttg
    15901 ccaaagcaca taggaatctc acctcccccc agtaatggcg ggccgatttg gttacggaag
    15961 tatcattatc gtagtcgcga ttctcatatt aaaatttgtc gcttaaaagc taaccttgtc
    16021 atggcgtaac tagagaatca aaatctacat gtactgatag atttgctatt catttgtcaa
    16081 agagcgctag gctattttca gcctatggaa atcctttatt ttgacccgat aaaaaacttc
    16141 catagaatga aaaggaaagg gaaaaaatac tttaacgagt tgtatcaaat tcaagtatct
    16201 tctcaatcaa ttttgtttcc agttgtctac gcatatattc atctacatac ataaccattc
    16261 ctttttcttc ttcataaact ggtttcatgg ctaaccgtga aatataattt tgatattttg
    16321 acagaacgat ggacatggca attgaatcac cagaagctgc ggctttgatt gtcgttagtg
    16381 gtatgaatgg tatatatcgt ttattttgct tcatatttga cacccaaata ctttcctagc
    16441 tcttccaaag ccatttgtcg ttggtaccaa acactgccga gacttttccc aataatatcg
    16501 ccaatttcac gatcattaag accgatgagg aaggacataa aaatgatttc ttgtctttga
    16561 ctaggtaatg ctgcaatcgc atttgccaac tcctcattgg aaataaagat tttcatacca
    16621 aggacaataa aagtaccact actattcaaa tttggttcca aataatagaa ctctgtacct
    16681 aacccttttt gttccaatat ttccattgat atttgccgtt ggcgaaatct agcgtacttc
    16741 ttttgaatat ttaacgcctc attgcagact actttcttac aaaaactgtc aaacgtatgt
    16801 tgaatgtggg tttcctctga gtcgcccata atattctccc cctcaaaaaa ttcattcaac
    16861 tcgttttact tctatccctt tccattatta ctacaatcta gga
//
LOCUS       DARPZJ010000051        16685 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.054, whole genome shotgun sequence.
ACCESSION   DARPZJ010000051 DARPZJ010000000
VERSION     DARPZJ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.054"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1366
                     /locus_tag="SLE23_002102"
     CDS             <1..1366
                     /locus_tag="SLE23_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEI8468986.1"
                     /translation="LTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPD
                     GTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDV
                     TPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLN
                     KEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVT
                     DTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKG
                     TVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDG
                     SQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSK
                     GSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRK
                     KENE"
     gene            1500..2843
                     /locus_tag="SLE23_002103"
     CDS             1500..2843
                     /locus_tag="SLE23_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8468987.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2955..4406
                     /locus_tag="SLE23_002104"
     CDS             2955..4406
                     /locus_tag="SLE23_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEI8468988.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4755..5387
                     /locus_tag="SLE23_002105"
     CDS             4755..5387
                     /locus_tag="SLE23_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HEI8468989.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5975..7414
                     /locus_tag="SLE23_002106"
     CDS             5975..7414
                     /locus_tag="SLE23_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8468990.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7709..7927
                     /locus_tag="SLE23_002107"
                     /pseudo
     CDS             7709..7927
                     /locus_tag="SLE23_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8176..8391
                     /locus_tag="SLE23_002108"
     CDS             8176..8391
                     /locus_tag="SLE23_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468991.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8608..8864)
                     /locus_tag="SLE23_002109"
                     /pseudo
     CDS             complement(8608..8864)
                     /locus_tag="SLE23_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9051..9962)
                     /locus_tag="SLE23_002110"
     CDS             complement(9051..9962)
                     /locus_tag="SLE23_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8468992.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9981..10985)
                     /locus_tag="SLE23_002111"
     CDS             complement(9981..10985)
                     /locus_tag="SLE23_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEI8468993.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10982..13105)
                     /locus_tag="SLE23_002112"
     CDS             complement(10982..13105)
                     /locus_tag="SLE23_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8468994.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13110..15557)
                     /locus_tag="SLE23_002113"
     CDS             complement(13110..15557)
                     /locus_tag="SLE23_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8468995.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15544..15933)
                     /locus_tag="SLE23_002114"
     CDS             complement(15544..15933)
                     /locus_tag="SLE23_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8468996.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15993..16496)
                     /locus_tag="SLE23_002115"
     CDS             complement(15993..16496)
                     /locus_tag="SLE23_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEI8468997.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16509..16670)
                     /locus_tag="SLE23_002116"
     CDS             complement(16509..16670)
                     /locus_tag="SLE23_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8468998.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         5391 a         3111 c         3071 g         5112 t
ORIGIN      
        1 tctaacagat aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt
       61 tactcccggc ggtacaattg ataccaacac accaggtaat tacgaaggtg tcattgaagt
      121 aacgtatcca gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg
      181 ttctgacgcc gataaatatg aaccaacagt agaaggcgaa aaagtagaaa ttggaggcac
      241 agtagattta acagataatg ttactaactt gccagcgtta ccagaaggaa caacagtaac
      301 agatgttact cccggcggta caattgatac caacacacca ggcaattatg aaggtgtcat
      361 tgaagtaacg tatccagacg gtacgaaaga tacggtgaaa gttccagtag aagtgacaga
      421 caatcgttct aatgcagata aatacaatcc tgaaggacaa aaagtgacta cagacttaaa
      481 taaagagcca gatgcatctg agggaattaa gaacaaagaa gatttaccaa aaggaactac
      541 ttatgcttgg aaagagaaag tagatgttag cacagctgga aataaaaaag gtactattgt
      601 agtgacatat ccagatggat catctgatga agttgaagta gacgttacag tgacagatac
      661 tcgttccgat gcagataaat ataatcctga aggacaaaaa gtgactacag acttaaataa
      721 agagccagat gcatctgagg gaattaagaa caaagaagat ctaccaaaag gaactactta
      781 tacttggaaa gaaaaagtag atgttagtac agctggaaac aaaaaaggta ctgtagtagt
      841 aacatatcca gatggatcta aagaagaagt agaagttact atttctgtag tagataaaaa
      901 agcaccgaat aaacctcaag ttgatcctat tacagagggt gaccaaattg ttactggtaa
      961 aactgaacca aatgcagagg tgacagttac attaccagac ggaagtcaac accatgggac
     1021 agctgataaa aatggtaatt ttacagttaa agttcctaaa ttagaggcag ggacaaaagt
     1081 gatagtaact gcaactgatg aatctggtaa tactagtgaa cctactaatg tagttgtttc
     1141 ttccaacaaa aaagacagtg gaaaaaacgg tagtaaaggt agtaagactg acaatcaagg
     1201 tagcaacagc aatcaagaca aaaatagagg caaaagccag tcctcaaaag tttttcctaa
     1261 gacgggagag agtgacagta atatctttac tattagcggt ggtttaatac tgttaggaac
     1321 gttaggatta ttagggtata aaaatcgaaa aaaagagaat gaatagaaaa tcaatttctt
     1381 aagtcttctc tgagaagagg aagaatcttt ttcttcctct ttttgctttt ttatgatggg
     1441 aaataagtgt tagttaaaga tgaatatact ttttatagaa aggaaaagaa tgtaattaag
     1501 tggaaaaaat agtaattatt ggttcaaacc attcagggct agccgcagct cgatttctaa
     1561 acttaagcga ttcaaattat gaagttattc taatcgataa aaaatcagaa attagttact
     1621 tggaatgtgg gacatcgtta tttataaaag gagaagtaag taatttagaa gatctttttt
     1681 atcaaaatag aatgacacta aattctgaga taaaaaagtt atttctagag acagaagttg
     1741 acaaaattga tattcaaaat aaaaagatta gttgtgtaaa aaaagatggt acaagattct
     1801 ctcaagaata tgacaaagtt atattagcta caggttcaaa gcaaattatg ctagatatac
     1861 cggggaataa tttagctaat attttttcga taaagaattt tccaaatgca aaagagattt
     1921 ttaaagcttt ggatgatagt actattaaaa aagtaggaat tattggagca ggatatattg
     1981 gagttgaaat tgctgaagcc ataagaaaaa gagggaaaga agtatatctt ttcgatgttg
     2041 cagatagagt gttgtcgact tattacgacc gtagtttttc agataaagtt gaagaaatac
     2101 tatcaaaaaa tggaatacat ctttgtctat cagaaagtcc taaaaaatat ttaggaagaa
     2161 aaaagattga aaaaatagtc actacaagtg gtacccaata ctctatggat atggtcgtac
     2221 aagctatagg atttctatct aatagtccaa ttggggaaaa ggaactcttg agagatgtta
     2281 gtggagcata tctaactaat gaataccagc aaacaaatat aaaagatata tatgctattg
     2341 gggattgtgc tacaactttt tttacgtcca ttaatagaag tagtgttgat ttttctattt
     2401 ctaatgctct aagaacagct tatattgcaa ctcaacatat taacaatcaa gattttacac
     2461 cttctggttc ccaatttaca aatggctttt ctatatttaa ttacaatttt tacgcagcag
     2521 gtttgaattt aaaaacagca cgattattaa gtgagtctat agattatata gaaatagaag
     2581 atttcattag acctgctttt ttgagaaaaa atagtcgtgt aaaattaaga attagctttg
     2641 aaaaaaatac aaagagaata gtaggtgtac aactttgtag tcaagaagat ttatctggac
     2701 tattatcaat gttttctctt gctatagaag aacaaattac attagacaaa ttgaaaatgt
     2761 tagattattt atttcatcct agttttagcc aaccctataa ttttatttta aaggcagtaa
     2821 caggattaaa cattgaaaca taatcgttac taaatgaaat caagaaatat actgtattac
     2881 tcaattcatt gaaaatattt atcataattt ttaatagaaa acactattaa agagaaaaaa
     2941 gagaggtaaa tcaaatgaaa aaatctttaa aacttgcatc agcagttata ttaatgtccc
     3001 aactccttat agcaacacct ttccatgtgt tggcaagcga aaattcaaca tacaaaattg
     3061 caaaagaaag aaccgagacg actgaaatga gtaattccga tgtaacagca gagagtagtg
     3121 aacttttgac aacttcatca agtgaaagta gtacgacttc aaatgccgag tcttcaacaa
     3181 cttcatcaag tgaaagtagt acgacttcaa atgccgagtc ttcaacaact tcatcaagtg
     3241 aaagtagtac gacttcaaat gccgagtctt caacaacttc gtcaagtgaa agtagtacga
     3301 tttcaagtac cgaatcttca acaacttcaa gtagtacaag tgaaataact tcttcgaaag
     3361 tgacaaaacc aaaccatata gaatcttcaa aaaaggaagc gccaaaaacg gaaggacaaa
     3421 caaaaacttt ttcgacacca cagcaaatag aatcaacaga atctttccaa tcacaaccaa
     3481 tactatctgg taatgaagaa attcattttg acaaaaatga atctgtagaa aattttatta
     3541 tgaaaattgg tgagtctgcg agaaaaattg gtcagaaata tgatttatat gcttctgtta
     3601 tgattgcaca agcgatctta gaatctgcca gtggtcaaag ccagttagct caggcaccga
     3661 attacaattt atttgggata aaaggaactt ataatggaaa ctttgtcatt atggtaacaa
     3721 acgaagattt gggtaatgga acgctttata cgacccaatc aaaatttaga gtgtatgaaa
     3781 actatgagga aagctttgaa gattatgcca aattattaac taagggaatt agtggaaata
     3841 aagattttta tgcaggagca ttaaaagcta atagtaaaac atatcgagaa gcaactaaat
     3901 tccttacagg acggtatgca acagatacac aatactattt gaagctaaat gaattaatta
     3961 aaacctacga tttaaccaac tatgataaag aagttaaagg tccacaaatg agtaagactg
     4021 gataccaagt gcctattcat aattattcaa taaccagttt gtttggaaat cgtggaaatg
     4081 aatttcaccg aggacttgat atggcagcta cacagggtga gccgattcat gcagttaaag
     4141 ctggtaaggt tgttaaagca gagtttcact actcttgggg aaattacgtg gtgatacaac
     4201 acgaagatgg atcaaccgcg ttatatgctc accagcaaca atacctagta aaaactggag
     4261 ataatgtttt gcaaggacaa ataattggct atgtaggaag tactgggaat agtactggcc
     4321 cacaccttca tttggaaatt tgcaaagata gtagtctttc tcagagcatg ttagttgatc
     4381 cgaaaacctt attattcgga gactaaaaaa ggtaatcaat ctgacaaagt aacaagaaaa
     4441 tggttggatt cttagacctt tgatcaggat attgagactg gaattgatat ctcgattacg
     4501 atgggtttga caaataaaac aagtccatta tcgaatatcg agtgtattat tgccgtcttt
     4561 atgctcatat tttgagcagg tttcactaga tgaaaacaat ttatctatct tgaggatttc
     4621 gtgtacgtat cgttcagtct tgtattgtaa attagtcata aaatcagact aagaaaaatt
     4681 ggaaatattt ttttctgatt tattaaaagt taattgaaat tatatggtac ttctttcttg
     4741 ggagggtagg tgcagtgaag gaaagatatg gtcaccttac tgttgttgag gagattactc
     4801 ataatggata taaaaaatat cgttgcctat gtgactgtgg gaatgaaacg attgtatatc
     4861 gatcaaactt actatcaggt agaaccaaaa gttgtggatg tggaaattat aaaaataggc
     4921 ataaatataa aaatttgaca aataaaactt ttggtaagtt agttgcaatc aagccaacta
     4981 aactgcgaag tgaaggaact gttgtttggg aatgtcaatg tctgtgtggg agaaaaaagt
     5041 tagtatcggc aaagcgactt ctaaaaggtg atgtaaaaag ctgtggatgt ttgaaatcaa
     5101 aaaagcatca cattgaaaat aaaaaattcg gattacttac tgcaaagtat cctttggaca
     5161 ataactgttc atggaaaaca aaatgggttt gtcattgtga gtgtggcagt atgtgtgaga
     5221 taagttatag taacttattt tttggacata ctcaaagttg tggatgttta aaaaggcaag
     5281 aaacaaggac atgtgttgaa gggacagtaa tagagtgtct aacgtcaaaa ttaccgaaaa
     5341 ataatacaag tggtgttaag ggagtttatc gttctaaaga gaaatagatt gcgtatataa
     5401 ctttaaaaaa aaagaggtac tatttaggat cgtatgattc tattaagagt gcagctcaag
     5461 ctagaaaaga tgctgaaaat aaattgtttc aacctttgat tgacaaatat cgaggtaatc
     5521 attaattatt gtggataata attaacagtg atatataaac atctataata tattattcat
     5581 actattgata tttagtataa tcctatggaa ttgaatatca tagcaatgta tttgaaaagc
     5641 aaattggaaa acaaataggt gcaacaccat aaatatgaaa aaattgggaa aaagtagaat
     5701 ggaaatttgc ttacgtctca cgagatagct cacactatta atctgaagaa caatgaagtc
     5761 gacttttaga aattgctaga agaaagtaaa gcgaattatc actagttact atagagtaag
     5821 ttcaaataaa gcatctccaa cttacatggt tacatgagga tatcaaatcg aaattactca
     5881 agcttcctat ggctagagtc gcgagaagtt gttgggcagt agacataggt tatattgttc
     5941 ttagctacac gatcattaga aaggaaatcc tattatgtat agttatcaag aagatgcaaa
     6001 agtccaaaaa aatcgctggt ggattttgat tgctatatct atgtttacct tcatgtccac
     6061 attggatggc agtattgtca atattgcact acctaccatc tcagatgata tgggcatacc
     6121 aatgaatcaa gcggaatggg tagtgtccgt ttatctgatg attgtctgtt cttgtttgtt
     6181 gctgtttggt aaaattggcg atagccgtgg gaaaatcaaa gtatttcgga ttggtacgct
     6241 gatctttgtc ttgggatcgc tgttgtgtgg gttcaatcat tcgctaggta ttttattgtt
     6301 cgcacgggtg gtacaagcca ttggtgctag tatgactatg gctacaaatg ccggaatcat
     6361 cacggaagtc tttcccatac atgaacgtgg tcgggcattg ggagcaatag gtgcgtttgt
     6421 ttcattaggc tcgattgctg gaccaggtct tggcggcttg attttgtccc aattttcttg
     6481 ggcgtacatt ttttggatca atgtaccggt gggaatcgta acgatgttga ttgctgaaaa
     6541 attcttacca aaagatatca ccatgagcgg ccatacaatc gatggagggg gctttgctgc
     6601 cattgcggct acgattatca gcttttttgg agcaatcttt ttggggcaag aaagtggctt
     6661 tttccatcca gtcccccttg tactgttcgt aatttcagtg attgcctttg tcagcttttt
     6721 aaaagttgaa aagaaagcag cctctccatt gatttctttc ggtattttta agaacaagat
     6781 ttttaccatg agcttgatta cagccttgtt gattttttct tccaacttct ttgtcaatgt
     6841 agtgattcct ttttatctgc aaaatgctcg cgggttgagt cctagctatg ctgggctgtt
     6901 gatgatggtc tttcctttga tgatggtcgt cggggcgcct ttaagcggct acctgaccga
     6961 ccgggttggc ccggagattt tggtattagt aggcttgggc ttattgtcgg taacccaggt
     7021 catgtatatg tttttgtcag tggactctcc tttgtggcta tacattgtcg ctactgccat
     7081 catgggtgcc ggcaatgcct tgttccagtc ccccaataat acgatggtta tgagctcggt
     7141 cactatcgaa aacttgggac tggcaggctc gatgaattcc tttgcccgaa atttggggat
     7201 ggtcagcggg atttcgcttt ctacgacggt cttatatcaa gcgatgtctg ctaagatggg
     7261 ccagcaagta actaactata tcgcaaatcg gccggatgtc tttttatatg gaatgaagat
     7321 taccttttta ggcagctttg ttttgtgttt tgttgccttt ttcctgacta tctggcgtat
     7381 caaaaaacaa ggaggtattc agaaaaatgt ctgaaaaaac cactgttgaa gaatttttgg
     7441 aggcctgcgt atgggtgagt gggatttcca tggatgatgg aagatgaagt gaacttctaa
     7501 aagccgaaaa actcaagtat tatcttcaaa atactagtgc tcaatgagat gcttgatttg
     7561 atcacaagaa gactgcgaaa gccgctggca accgcaagct aggtatccca ccgatggact
     7621 acgttttaga ggctactggt tatgaatacg gagccaacgc tctcatctgc ataagaatac
     7681 atcacccaga ttatgtaaag attttcgata cttctgtcaa aaaatcatta agatagataa
     7741 atgatttccg tctagtcaaa ttggttcaga atgtagacac acagatggta agaagtcact
     7801 cacaattcga gaatggactt gtcctatttg ccgtatacat cataatcgaa acgtcaacga
     7861 tagtatcaat attttgacca agggctatga atacaagcat tgccttagaa aacatcaaga
     7921 accttaggaa caacggggat agcttggtta ataagagata ccgctgttta ggcttgcaag
     7981 tatactcttt tatcaagaat tccgtggctt tagtcatgag aggcttaata ctatgaaaat
     8041 tttctttagc atttttgatt taggttcctt ttctaattat aataagatga ccactacagt
     8101 aacctactga aatatataaa cagccactgt agtaccattt tcaaagtagt ctatgagagg
     8161 agaatcttca ttcttatgaa cgctggaatt gcggatatga atttaataaa aaaaaccctt
     8221 aatgatttta cttccaattc aatatcaaaa ggtactggta tcaatttaag cacaataaaa
     8281 aagctgaaaa gtggtgaaag atcagtggaa aagctgaatc ttttagatgc tataaaaata
     8341 acggaatttg ctatgaaaaa tggaaaagct gagattgaaa tatggagata attatcgtct
     8401 agtgaattac ttgccactta gctgaattta acgatccttg gtgcttgaag ggggagattc
     8461 ttgggaatag agcatacttg caagcctatg tctttactaa caacgatatc tcttattaac
     8521 caagctatcc ccgtagttct aaggctttta cttttatcta agcaataatc gtattcaaag
     8581 gaaatttttg acccttagaa agtctcattt tatcagacgt gagcttaggc attgctgaat
     8641 tttgttaatt cggttttagg ttgtgctttg agcataatat gaaagtattc tttatcacga
     8701 tttcattcat ctaaggtaat gtgatgtgat tctgaaattc tttcaaaggc agtttttgca
     8761 taagctgaca ttacatcatc aatgacatgt ttacaatgtt tcactactaa aataaggggg
     8821 taaccaagaa gaaaaactga atgattattt gtatctaatt ccatggtata tcaaccattt
     8881 cctatataga ctgattatga catggattaa aataaaaagg cactatgtct taattgtcgg
     8941 ttttcgagtt accgaatggc attcatcacc cacctataga ggatgggcga cttctgcctg
     9001 aaataagtta cactacttat aacttctaat aaaattagat tgagtcatta ttatttaaca
     9061 tcaacgattt tccagtttcc atttttttgt aatactaatt tgtactgaaa gtagctagtg
     9121 gtttttgata cattatcaag gtattttatc tttgtactca ctagaaaatt ttttccgttt
     9181 tgtagataaa ctggattctc taactccgaa aactttaagt caatattgat tggtcgcatc
     9241 gcaccatttt caacataata ctccaattct ttttcagaag ctgatggata aagtttaaaa
     9301 aatgtttcta aaaaatcggt gatttcttcc gttgttttgg catcaatttc tgaatcgttt
     9361 tctacttgtt ttgcttcata ttttgccttg tctggctttc caatcattgt tggcaaacta
     9421 gttactaaat gattcctgtt ttcatcttca aagattgtca ctcgatatgc agaagaaatt
     9481 gattgcgtct tttttccctc tgtaatatgt tgctccacta aaaatgaaac gacaaattct
     9541 tccgagtgtt tttcaacatc tagaattttt acagattgaa cttcggaact cgtgggaata
     9601 tctgctcgaa ccatatcttg gattaaagcg agaccgtttt ctgtaaggta ctgttcgaga
     9661 ttactcattc tcttttcaat tgcttctttg ttatttttcc atgaaaaata ttctttcgca
     9721 aaatcctctg taaaactttc aacgccagaa gtattcacta ccttctcttt tataaccact
     9781 ttttcatgag ttgtatgttg atcaatggcg gtgaaatttt tataaacgcc aaaagcaaga
     9841 ctacaagaca ataaaagcca aagggcaagc accatttttc gatgcttacc cacggataca
     9901 actcgttctt ttttcttttt tgggctcttt tccttttgat tccgttcaat ttttatcttc
     9961 attctttttc ctcttttctc ttatttgtat cggccagctc cgataagatg ctgccgccaa
    10021 tagttttccg ttagattcgt ccaccccact ggatctcctg catgaaacat gcgattctcc
    10081 cctgcgtaaa tgcccacatg ggtcacataa gtaccggcat cataggttga atgaaagaaa
    10141 actaaatcac ctggtttggc atcttttaga tcaatatgag tcatggcatc atattgatcc
    10201 tgagccaccc gaggaagttt caggtcaact ttggcataac accattgggt caagccacta
    10261 caatcaaacc ccgtttctgg acttgagcca ccaaacacat aggccgttcc ttcatactta
    10321 aatgcctcat caaaaatttc ttggactatt ttgtcatcaa actgagttgt agttaggtat
    10381 tgcttcacta ataaacagta aaacatattg ccataattat accgccaccc accattttcc
    10441 ttaatcgcga ttgggttggg gtaatcgact ttttgaccac ctgatttttc ctttgaaaaa
    10501 gattcagcta aagcaaaact atgcttcttc ccgtttttcc cgacatgatc tagatacccg
    10561 ccaccatagt tataggcctg aataatacta tcttgatcac accctagttc tttggaacgc
    10621 ttaaccaaag acgcaaaata gagacagcct tgtttgatgg atgcctcggt acttaatgaa
    10681 ttaggtggta atccggctga ctcagaactt tgcataacgt cttccattgt gccaccagat
    10741 tccacttgaa taatcgccaa aagaattgga atatactctg ttatatccga ttctttggca
    10801 tacttttcca ccattgcacg gtgtttcaat acttcttctg agacactagt tccgccagga
    10861 gaagtgccag aactaccatt tccctcactg tcttcaccaa acaacaaacc cacacacatc
    10921 aaaataccca taaaagagat ggtcagaaaa gttaatgaaa taacacccac tttcttcaag
    10981 ttcatttttt ctcacctgac cttgattttg gacgatggtt cattcttttt tgtacttttt
    11041 gattggtctg ctttggcaga gtggacctct gtttcacttg ttggaaagaa tttttcttac
    11101 ttgctgattg gcttttccct tttgaaatga tttcttgact agttagtttt cgtttgattt
    11161 cgggattcag atttgctctc acaatccgct ttggtgcttc ttttttcagc atcatatctt
    11221 tctgaggttg agctgcttta tctattggaa tattcgccct tctttttccc tgacgatttg
    11281 ttgcttcact cagtatcttg cgtttttcgt ccattttcgc atttcttcgt tgtcgttgtt
    11341 tttctcgcaa atccactcga tccgcttttt cttggaacag tccgcgcttg aattcttctg
    11401 gtgctttttt cgacttttcg attcctttat ggagattgta tttcaaattc gttggcgtat
    11461 tccttacctg atcctttact tgtttagtct tatctttcac caaagcttgg gtatccaaaa
    11521 ctttgccgat ttttctccca gccaaattca ttcgggattg tttcttatta tttgaaactg
    11581 gattctcctt agttaagtca gatagtattt cgtgatcgtt cggtaatcgt gaattctttc
    11641 gtagagaaga accggatggc ttaaatttgg attttgattg ttcctttgcc aacttatttc
    11701 cgactgctgc accaccacca aaagccaaag ctcgtcccac atttcgattg agttgccgca
    11761 attttcgatt cattaacatt tgcggttttc gcatgacgcg tcttcccatt gactggctat
    11821 cattactctg gaggttgaac atactcataa tgtcgcccaa tttgaaatag ataccggcaa
    11881 aggtcacaat ttgcagaaaa gcaaccatga aaaatggata ggttgccgaa atattgaaaa
    11941 acatcgtgga gatgctaaat gcagtcgtaa tcaccaaagt aacacccgct cgcatcataa
    12001 tcgtattgaa taaacgaata atcgccttct ttcctaaact ttcataagtc ggcaacatgg
    12061 acaataagaa actaattggc agaaacatcg caaagataat gaagagaatt tgcgagaaca
    12121 acataatccc tgttagaaga aaaacaaaga aggaaatgcc aatattgaac aataccaaaa
    12181 agaccacggt ccctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattgt
    12241 cttcaatctc tgccttgacc gcttcttccc gatctttgcc tttgttttca tctggactca
    12301 cagatagaat cttgttgacc cggtcttcac caatttcttc tatgttggaa tcatcaaatt
    12361 gcagtagtaa ccaaggttgt tggacttgaa tcgaaaacaa actatcccga atcaaatcca
    12421 cactatcttt tccttggctt tctgaattgg gtacaacgat ctcggttcca agggtaaggg
    12481 ccgcttcact aacatctgag ctaaagtcat tgatttttgt gatataggta ggcgcataag
    12541 caatgaacga acccgatagt agaaaaatca tcacaaaatt aatcacggct cgaactgctt
    12601 tcgtggtttc tcgttttaat aatccggtat acgccacata cacccccaga gctaaaatca
    12661 tcaataatag aaacccaaaa taaaatccgg aggtctggag tccattttca gtaataccag
    12721 ccaatgtttg gatattcttt ccaatacttt cagccgtatc cgaaatgaaa tctaatttgt
    12781 aagcctcttg aaccacataa cccgtggcgt tcgacaaata caaactcacc gtccaaatga
    12841 aattagtaat ggcataaaga ccatacatca cgcttttccc taagccatca ccccaattcc
    12901 aaggcaacca atcccaagag ctatccacaa agaaatctag ttgatagttg ttcagtgaat
    12961 atttggaata tagatttcct gcttcaactg tatcatcaac tagccctgtc gcctcggcta
    13021 ccgtaccaac taaactcaat agaactatca gagtgagtat gctaataaaa acgattccca
    13081 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac aggtggacgg
    13141 gtatcaaagg catggaagag ttcttcaaag actggatgta cctgaaccac gcctacccga
    13201 ccatacaaat cctgcatcaa gcattggcca ttttccaaat ctcgtaggcg tttttgattg
    13261 ctttcatctt ctcgatccaa gccaaagaat tccaaggttt tcttgatttc atgaatatcg
    13321 gtactgcgaa acgcaaactt caacccgata ttattcttca agcgttcatc cagtaaatca
    13381 tcactatttt gcgtgacaaa gtaaaccccg gcattcatag cccgcccagc acgaacgagc
    13441 ttattcgata atgttttccc ttgcgctact tgaagaaaac tccacgcctc atctaagtct
    13501 acaattttga agatttctcg attactatgg ataaagtcca aggcaaaagt ggaaatgacg
    13561 attagcatgg aaacactaag caattccatg gtggtatatt cttcaaaagt ggtttctgca
    13621 tctggtaaaa ccaaatccgc tacttgaatg atatttaact gcctatctaa actaatcgac
    13681 tgggtaatcg aaccatctga gaaaagcaaa tgggcaaaat cataatcggt aaaggactcg
    13741 atgtgatccg cgatattttc cgcaactggt gagccttctt ttcgaagctc attaattact
    13801 tgtaataatc cccgttgatt gctttgggta accgtccgaa tggccttacg caacactgga
    13861 aacttctccc catctcgact agaaattcct gttaaaaagg tcagaatatc aattgctaga
    13921 ctttcagaat ccttcttttt ctccataatc acataaggat caagtaatcc ttgatttttt
    13981 ggcttactag ttaagttgag aatattgatt tcatccgcaa tttctggcaa ggtttctttc
    14041 cagccacccc gttccccttt tggatcgaca atcacagctt gtccaccaaa aaggacggcg
    14101 taataaacta agagattgtt actaaaggac tttccgccac cgagtgaacc gaggaatgcc
    14161 gctgctagcg cattggtaac tgaacccttg accccttgtg aggccaatgc cggtttcagg
    14221 taaacattgc gccccgtatc tacgttataa ccaaagtaaa tgccttccaa ctcccctaac
    14281 atctgagtgg cgccaaaacc aagtccggcg agaaaatcag acgtaacata ctggatataa
    14341 tcattcatgt atcgcttact agaaggtaag aattcttcat gtagccccat catatcgcca
    14401 aaaggccgga ctagttttac attggtatca tcataaaaat ctagcacttc atcacaccgg
    14461 cgctttagtt catctactga ttcggcactt actcgaacca catagctcag tttgtacatg
    14521 gattctttgg actgatccaa ggtagtttcc aattcatcta cggaatccaa tgcatctaag
    14581 acattggaat ttgtttcatt gtcagattga taggcatggt tgtccaagtc ttttaattcc
    14641 tttttcttat tgcgaacggt agcaagtgcc tttttgttcg tcacaatctc cacattcata
    14701 ctagtgtcaa ttgggaatgt aaattgttgt tgctggtaat agaaaagttc tgaggaggga
    14761 aactccattt cccccacaat tgtattaatt gttaagtacg ctacatatga ttcatgattc
    14821 tcatgttcca tgcataagta ccggggcttt tcttcaatca aacaacgact gggacgtaat
    14881 aagtcgtaac gtttcaccaa agtttccgac ttcagctttt tctttggtag ctgaaattca
    14941 tattcttcaa atggtgtacc cttttcgcca tagatatgtt caatcaaata catcagatca
    15001 ctcggtgtga ctcgtctgac tttaaatctt cgagccaatt tactttccat tagtttttca
    15061 agcttggtat atcggcgaat ttcttcattg gataaggaaa caaaatcgcc catcaaatga
    15121 tgattcactc catagacaaa ttcttgaaag ccggagaaga aagatttctt gagattcttt
    15181 agattgacct cttcatctgt cgcaatcagt ttgaagccaa taaaaaagcg ataatcaatc
    15241 tgactatcgc caatcatgga tactaatgcc tctgtctgta aatcaattcg ttgtttcgct
    15301 acttctgtta atcgcccggt aatttccttt tttgatcgtt cttgcgtggc acgaatacta
    15361 ctttctgtgg caatttgtaa ggcatgaatc ttgccttcac gattttgcgc aatcaattga
    15421 cgaaagttat cgtggacttg atatttctgt tcaggtgaca aaaaggagta attgtaaggt
    15481 attaactcat agtaggcaaa acattctccc tcttgattaa agacaagatt attttcaata
    15541 tacttaatcg ggtacatagt tcacactcct taccagagta atgggttcgt cccatcgttt
    15601 cttctgttct ttgactttct ttcctgcgaa agtgacctta aatcgtaagt gatagctaat
    15661 aaaagatcgt aaaaatccca atggtttctt accgtcaaac gttttttgcg acatgaacca
    15721 agtaactgcc accggtatac ctaagtattt taaaaaggcc ccctctatca tagatagtgg
    15781 aggcacatgg gcaaatacga tgacaaacag caaggataaa acaaaccaag ccatctggtt
    15841 aaaagtcaca ggaaaaggca gttgaaagtc attaattgca taaatgacct tttcaactgc
    15901 ccaaatactg gtgtagcttt ttattttctt catcaaatca ttcctttaaa aagaaggata
    15961 gtttagaaat caactaccct tcaataattt tgttaatatg gatactcaaa aacacctcga
    16021 ctcgttacca aataattgcc tccaatctcc aagtctctac cacacgcatc aaaatcaata
    16081 tacgtcttca agtgttctgg tacttctcca aaatcaccag cttctacaat caagaaatat
    16141 gctacatcac tcatatcatc gcaatctgga taatagataa tatcatccac atgctctacc
    16201 atctcctcaa aagaattgaa gaaagcatgt tgaatctcag aagcaacttc accaactggc
    16261 gttccttcaa gttcctccgc taagccacac aaccgattaa tttcctcaat tggcgtatac
    16321 tcatcaatct caaagggaag ttcataatca tgaattgcat attcctcgta ttcgtcattt
    16381 aacccaattc gttctttcac ttcatcaaaa tcgacaggtg gggtaaacca cgcccccacc
    16441 aattcacctt cgttatattt cccgaggttc gcaatataaa cacgcatctg ttccatcgtg
    16501 cttccccctt acgcaccgac aattcggtta aacaaactga gtaagacatc cttcacccca
    16561 gaagcattaa agaccaatcc gaccgcaatc aaagcaatca ccaaaaagcc aatcagtttg
    16621 gaaaactccc gcttaaatcc taaaaacaaa ccaatgacca caattgccag taagactaag
    16681 gattg
//
LOCUS       DARPZJ010000052        16585 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.055, whole genome shotgun sequence.
ACCESSION   DARPZJ010000052 DARPZJ010000000
VERSION     DARPZJ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.055"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..495
                     /gene="scm"
                     /locus_tag="SLE23_002117"
     CDS             <1..495
                     /gene="scm"
                     /locus_tag="SLE23_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEI8468999.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSK
                     TSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYK
                     KSKR"
     gene            complement(650..1636)
                     /locus_tag="SLE23_002118"
     CDS             complement(650..1636)
                     /locus_tag="SLE23_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEI8469000.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1659..2225)
                     /locus_tag="SLE23_002119"
     CDS             complement(1659..2225)
                     /locus_tag="SLE23_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HEI8469001.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2239..2655)
                     /locus_tag="SLE23_002120"
     CDS             complement(2239..2655)
                     /locus_tag="SLE23_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEI8469002.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3112..5046)
                     /locus_tag="SLE23_002121"
     CDS             complement(3112..5046)
                     /locus_tag="SLE23_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8469003.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5327..6283
                     /locus_tag="SLE23_002122"
     CDS             5327..6283
                     /locus_tag="SLE23_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HEI8469004.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6373..7476
                     /locus_tag="SLE23_002123"
     CDS             6373..7476
                     /locus_tag="SLE23_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEI8469005.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7489..8442
                     /gene="menA"
                     /locus_tag="SLE23_002124"
     CDS             7489..8442
                     /gene="menA"
                     /locus_tag="SLE23_002124"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HEI8469006.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9377..10723)
                     /gene="gor"
                     /locus_tag="SLE23_002125"
     CDS             complement(9377..10723)
                     /gene="gor"
                     /locus_tag="SLE23_002125"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEI8469007.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10857..12110)
                     /locus_tag="SLE23_002126"
     CDS             complement(10857..12110)
                     /locus_tag="SLE23_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEI8469008.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12116..13039)
                     /locus_tag="SLE23_002127"
     CDS             complement(12116..13039)
                     /locus_tag="SLE23_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEI8469009.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13260..15752)
                     /locus_tag="SLE23_002128"
     CDS             complement(13260..15752)
                     /locus_tag="SLE23_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEI8469010.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15759..16226)
                     /locus_tag="SLE23_002129"
     CDS             complement(15759..16226)
                     /locus_tag="SLE23_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEI8469011.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16362..16435)
                     /locus_tag="SLE23_002130"
     tRNA            complement(16362..16435)
                     /locus_tag="SLE23_002130"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16399..16401),aa:Arg,seq:acg)
     gene            complement(16493..16566)
                     /locus_tag="SLE23_002131"
     tRNA            complement(16493..16566)
                     /locus_tag="SLE23_002131"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16530..16532),aa:Pro,seq:tgg)
BASE COUNT         4897 a         3467 c         2954 g         5267 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagcacgga cacgtcagct
      181 tcaagtgaca gtacagatac atcctctacc acaagtgata gctcagattc atcaacttca
      241 agcgatagta cagacacgtc gtctaccaca agcgatacac gtcatgcaag tgtctccttc
      301 tcaaaaacaa gttcggataa caggacgaac tttaacttaa ctaataaaac aagcaatgac
      361 aatggaaaca aatcaaaaag agcacttcct aaaactggaa gtcaatcgaa taattggata
      421 acactcgcag gcgttatatt acttgtaatc ggtttaagaa tcacttttat gagttataag
      481 aaatcgaaaa ggtaaaaaaa tattcaagat aaaaaagagc aacgtcgcta acggacgttg
      541 ctctttattt ttgcttttta tcataaatac aagaactaca attcaatttg tcaaaaaaca
      601 cgtagatttc cttctgagaa atttatttac gtatcgaacc tttccctatt cagtctttgc
      661 gatccaaaat cagttgggta agggaaaaga gattctcttt tgttcgaaga gaggtggcag
      721 gtaatttctt tatttccttc aaagcctttt ctgtgtaaga ggccgctaac ttcctagctt
      781 cttccacgcc tcctgtatgt tcaacgattt tgcgtacggc gtcgacatct tcttctgtca
      841 ttgccgcttt cttctctaaa taaggtagta gctttggttt gtttttttgc aaagagtaga
      901 tcaacggtaa agaatagacc ccttgacgca tgtcttctag tacaggtttg ccgatttcct
      961 ggctctcttt tgtataatct aaaatatcat cgataatctg aaaggccatc ccgatagaaa
     1021 gtccgatatc tcctgctttt tttgcgaagc gctcgcttgt tccactttca aaagcgccaa
     1081 cagaacaact taattggaac agttcagctg tcttacctga aatattttcc aaatattctt
     1141 ttacagaaag ttcataatta tagcgatcat ccatctgccc taattcgcca ttcaatactt
     1201 tttccatact gcgagaattc aattggagac ttttcaagga agtggagtaa tcagacaata
     1261 gtttaaaaca gcagacaaat aaatagtctc ctgcatagac agaaacgaca ttaccaaact
     1321 gactacggat attaggctga ccacgtcgca gatccgcttc atcaacgata tcatcatgga
     1381 tcagtgtggc cgtatggagc atttcgatag aagctgccaa agcgatggct ttgtctcgat
     1441 cttgctctgg tccaaattgt gagaacaata gctgataggc aggacgcaac agctttccgc
     1501 cggcatggat cgtttctttg atggcttgtt cgacaggttt gtttttcagg cggacagttt
     1561 cttccatccg ttttagtgtt tctgtcaatt ctttacttaa agcaggatag ttttcccaca
     1621 ttggatgtag cttcataaaa aaactccttg tgtgacgatt attttttggt aaacattggg
     1681 ctccattttt gtttggttcc ctgctcataa tctttttgga atcgttgaag tgtctgcaca
     1741 tgtcgtaaaa gataattcgc tgcgatcccg attgcaatcc ctgataaaat ccctaaaact
     1801 gaaaggactg gcaagtacaa catgactgtc catgattgtg caatgaaaga agccatcaaa
     1861 agctgtccga cattatgcat gaaaccgccg gccgcactaa ttccgatgat actgacacgt
     1921 tttggtccta attgcttgac caataacatt ccaaaataac taagcaaagc accactcata
     1981 ctataaagga atgtggaaat cgttccgcct agcaaagtag tcaggaatag tcgtagccaa
     2041 agtagtaaga agctgtcttg ttttttcatg gtaaaaatgg caacgatcgt gattagattg
     2101 gctaagccta gttttgcacc aggcgcaaaa gaaaaaggat aagggatcat attttccaat
     2161 aaaccaatga tcactccttg tgcaacaagt agcgaaatat aaatcatttt ttgtaattta
     2221 ctcatggtgt gtgaaggtct aataaatcag actgtcttcg tcacctccat ctgttgaacg
     2281 gacttcgatc actaatttat gtggcaaaca gacgatggtt tcgccatttt tcgttgccca
     2341 gcctcgacgt acgcagatct ggtcatcgca atctgcttct tttatccgta ctcgatcgcc
     2401 atctatctcg atcaagttat aatctccgtg ttcatctttg taagtatatg tgttgctctc
     2461 ttctccagcc atcaaaggga atgttttgat ttctgtgcca tccacacgca gtaccgcttc
     2521 tttttctgct gttgcggtgt tttgctgaag accaaaaatc atgactggta aaaaagaaag
     2581 aacagtcaaa agcaaaataa taaaaacatc ccaaggtttg agcagacttt tttcagcaaa
     2641 ttctttaagg ctcatttttg ttctcctttt tccagattaa ctcacccaat tttagcataa
     2701 aaacaagagg ttgtgacacc tgtgtcttgc tttgagtaat aagaacgaag aatagaaaac
     2761 agctttccat gttttctaat tctttgggct tattaccgag aagcagcagg tggaacaccg
     2821 tttataacaa gaggttgtga cagaagtggg caacttcaag aaataagaag gaatttacga
     2881 aaattacttt tcaagttttt gtgaaatttc ggcttatttt tcgaagaagc tacttctgga
     2941 acaccgttta taacaagagg ttgtaacaga ggttgtgaca cctgtgtctt gctcatggag
     3001 gcttatctcg ggcatcttat tcctttaatt ttacataaaa aggaggctgt gacggtttgt
     3061 ctcagcccct ttctattgaa atcttgcatt caaataacgt tctttatcta tttatttctt
     3121 gccgtactgg gaacttggtc taccgtacca ccaattacct agtgtacgtt gtagccatgg
     3181 aattacccag cgatccaacc caatcgcacg tccggaaccg ttcatcaatg cgaaagcaac
     3241 aaaaatgaac caaatgttta cccagtaaaa catgcctgat aagcagaacg tgatcaccaa
     3301 tacaatcgtt gtcgcactgc atagccatgt gaataatcca gcaatcaatg ctaatgccaa
     3361 ggcaatttca aagaatacca tgaatttttg gaagaacatt gctacatcat tgtttggcat
     3421 gatcacttgc atgatctttg tgaaccagtc tggtgacttc tcaatcacag ccattggttc
     3481 ttcaccgtat gcataactca aaccaaaatg tgcagcttga gtcgctgctt ctccggcact
     3541 tgcccctgct ccgctggcag ctgtggttgc atcaccagca gcagaagcac cactggcaac
     3601 atctgttaca ttgtattccc atgtccaagg gaacacactg tttccagtga accatgatcc
     3661 ttcaccaaac caagtacttg gtttgaacac ttcaccattc ccaatgattt ttttggaagc
     3721 ttcaacgaac caaactaaac catagaaaat acgaagtggc acactccata agacattgcc
     3781 gtaacgagaa gaatgtcctc gagtcacgtt gcgatcatct ttgatatgga aaaactcatg
     3841 cattaaatat tggaacatat aataaccaga acgaatatca aagaagtatt tcaaattcac
     3901 gatatgtttc attacgatag ctaaaaatcc gcttaaatgg atcttatcaa ataggttagc
     3961 taccccccat ttggcaccaa tagaaaccat aaatccttga tagtttcctt taaatttatg
     4021 cttttctccg cctttgatcg aagccacgat attcgctgcg gctgtgtgtc ctgtttgttc
     4081 agcagcttga acgatctgcg gtgtcggtgt tcctgggaat tcttcataaa agactaaatc
     4141 accaatgata tagatgtttt tatcttcgta gccttttgcc tgcatatatt cattggcgat
     4201 caaccgctgt ccgcgtgctg attctaatcc aaagtcagca gcgtcagaag ttcctttgac
     4261 accagctgtc caaatcagtg tgtgagtcgg aatgttgcgt ccgtctttca atttgatatg
     4321 atcagcagcc acttctacga ttggtgcatt caataataat tccacgttgt gcttacgcaa
     4381 atagcgttca gcttttgcag catcatttcg atccaacata ttcaagatcg tcggcattgc
     4441 ctctacgacc atcagtgtga tttcgtttgg atctaattta taatctttgg ctaggcgatt
     4501 tttccagtcg atcagttccc caatcatttc aataccggta aatccagaac cacagacaac
     4561 gaaagtcagc atggctttac gcagttcatc atctggttcc aatgcagctt ttgctactgt
     4621 cttctcaata tgttcccgaa tccttacaga atcttcaaat gaccaaaggg tgaatccgtg
     4681 tgctttgaca ccaggtgtac caaagtcatt cggctctccg cccattccaa ggatcagctg
     4741 atcaaaagga taggaaccta atttggtctt gacgattttt cgttctttat cgataccgat
     4801 tacagtgtct gtgacaagtt gtacattctt ttgacgagca aacaaatgct gcagatcgta
     4861 ttggattgct tctggttcta cacgtccgcc agctacttca tgcaactcgg tcatcatagt
     4921 atggtacgaa tgacgatcga tcagagtaat tgctacatct tcttttttca gtttctttgc
     4981 caagtatttt gtagctgaaa caccggcata tcctgctcct acaacgacaa tattttgctt
     5041 tgccattgat catccgctcc ttatagacta tctatataat gaatatatga taattctttt
     5101 agtttgatac ttattacaca atctccatat attatataga tgttctgttc ttttgtctaa
     5161 ctccttttgg atttttttca aattttaaaa taaagcgttt tttcacgaaa tttgctgaaa
     5221 gaaaacgttt gaaatattac atgggttatt tatcaaaaat agttgactta taggctaaaa
     5281 agattagaat gtataatgaa tcacaaagaa aaattgtgga ctagaaatgg aatggtgggg
     5341 tattaaaatg aagaaaaaac gttttgtaac tggatttgcc gtattagcat tttcagctct
     5401 agtgttaggc gcttgcggcg cagatgacaa cggaagctca aactcttctt ctgaatcatc
     5461 tacagcacaa tcttcgactg caaaaagcac aacagaatca tctgcaaaag ttgtagctgg
     5521 cggagatttg caagacggca catataaatt agaagaaaaa aattattcaa atggttaccg
     5581 tgcagtcttt gaaatggttg taaaagacgg caaaatcact gaatcaaaat atgataacgt
     5641 caatgaaaac ggcgaatcaa aaacaaaaga tgcagaatac aacaaaaaca tggaagcaaa
     5701 atctggcaca aacccagaaa aatacattcc tgagttgaat gaccaattct taaaagcaca
     5761 aagcgcaagc ggtgtggaag tcgtaactgg agctactcac tcatctgaaa gcttccaaaa
     5821 ctacgcacaa caattgatcc aagctgctca agctggtaac acagatacaa tcgaaatcga
     5881 caatggtgct gatttgaaag acggcactta caagcttgaa gaaaagaact actctaacgg
     5941 ctaccgtgtg caattcgaaa tgacagttgc tggcggcaaa gtaactgaat caaactttga
     6001 ttatatcgac aaagacggta aatcaaaaca agatgataca gaatataatg aaaatatgaa
     6061 agcaaaaagc ggtacagaac caaaaactta catccctact ctgaacgacg aattcgtcaa
     6121 agcaatgggc gaagaagatg gctcacctgc taatgtagaa gttgttacag gtgctacaca
     6181 cagctcacat tcattcatca tgtacgcaca acaattagtg aatgcagctg aaaaaggcga
     6241 cactcaaaca atcgaagtag ataatatcgt aacagaaaaa taatcacata atcatactaa
     6301 taaaagttgg agggtgggac gatagccaga ttaggcagtc gtctcacctt tcaaaatgaa
     6361 gagaggaaaa agatgcggaa aaaactacta ttttccttaa tcacactggg catctctttt
     6421 atggtgctaa ctggctgcag caactcagca aataaaacaa ccactgaaag ttcagcagct
     6481 accaagatat tgaaagatcc atattctgat gaacagttct tgttagggac ttacgttcgt
     6541 atccgtgtgt atgatgaagg caaagaatca gcattgaaac ctgccttcga tcgagtaaaa
     6601 gaacttggtg ataaaatcac gatcaatcaa aaaggttctg agatcgatga agtgaatgag
     6661 caagctggga tcaaaccagt aaaagtttct gatgacgtct acacgttagt caagcgggcc
     6721 tacgaatata gccaagattc tcaaggcgga ttcgatatgg cgattggtgc aatcacacaa
     6781 ttatggcgaa tcggttttga tgacgccaga aaaccttccc aagaagaaat cgatcaggca
     6841 ttgaaattag tggattatca taagatcgaa ctaaatgaca aagaaaaaac tgtttatcta
     6901 aaagaaaaag gaatgatcat cgatttaggt gcaatcgcca aaggttacat tacggacgaa
     6961 gtagtgaaag tcttgaaaaa acaaggagtg accactgcca tcgttgactt gggcggtaat
     7021 gtctatgtct taggccacag cccaagaggc gaaaaccaag actggacagt cggcatccaa
     7081 gatccgaaca tggctcgcgg atctgtttta ggttctatta aagaacggaa caaaacatta
     7141 gttacctctg gaatttacga gcgttattta gaagtagatg gcaaaaaata ccatcatttg
     7201 tttgatccaa aaacgggtta tccgttcgac aatgatatcg caagtgtcac gatcataaca
     7261 gataaatcaa ttgatggtga cgggttgtct acagcagtct tttcaatggg tgtgaaaaaa
     7321 ggactggaat acgtcgaaag cgaattgaat aacgggacgg aagcgatctt cgtgacaaaa
     7381 gacgataaag tatatgtgac cgatccaatc aaagacacct tcaaattatc ggaggactcc
     7441 cattacacga tgggtgaccg ttctgaacta aaataaggag tacgaaccat gacactaaaa
     7501 atctttttag aagtagttga aatacgaaca aaggtggcta gtgtatttcc ttttgcggta
     7561 ggggtattat tctctatcgc tttttttcat gagatacatt ggctaaacac ttttttattt
     7621 tttattggaa tgctagtttt tgatttagcg actaccgcta tcaataatta catggattat
     7681 gaaaaggctc attctgaagt atataagtat gaagaaaatg tcattggccg cagaaatcta
     7741 tctcctgtat tgattcgaaa catgatttta gctatgattg catttgtttt tgttatcggc
     7801 gttattctaa cgatcaatac gggttggctt ttacttttga tgggatttat ctgttgtttt
     7861 attggagtat tctatacatt cggaccgatt cctttatctc gaatgccttt aggggaaatt
     7921 ttcagtgggg tgactatggg ccttggaatt tttgccatgg tcgtttatgt caatacattc
     7981 ggttcagatg tctatgatct gacagtcaac ttttcatctg gacaatttga tttggtagga
     8041 aatctttggg ctatagcagc aatcgtatta gcttccttac ccttggtgtt tacgattgcc
     8101 aatatcatgt tggctaataa tttgcgggat cttgaccgtg atattgaaaa tcatcgctat
     8161 acactagttt tttatatcgg acgtcctgcg ggaacagtct tattccagct attgatgtat
     8221 gcttgctatt tcgtgatttt aatggggttg ttgagcggta tctatgaatg gccgatcttg
     8281 gtcaccttct tgaccttgcc aattgtgaag aagcatttgg atcaattcaa gcaaacgtta
     8341 ccccagccta tcagtttcag ctattccatc aaaaatatgg tcttattcaa tgccagttat
     8401 gtattggggc tattactaac aatcattatg caagccattt aacagcatga agaggttgtg
     8461 aaaaaactgc cctgcatcaa gtaataagaa cagccaaata aaaatagctc cttatatttt
     8521 tcgtttggtt gggcttatta ccgcagatgc aagcttttga acaccgttta tcaggaggtt
     8581 gtgaaaaagt cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat
     8641 ttttgcataa atttggctta ataccgagaa actggctttt gaacaccgtt tatcagaggt
     8701 tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
     8761 tttttgcata aatttggctt aataccgaga aactggcttt tgaacaccgt ttatcagagg
     8821 ttgtaaaatc agtgttttgt cctgagtatt agagaaacaa atggaaaaat agttcctcat
     8881 attttgccgt tttttgagct aataccgaag gacagctgat tgaacactat ttgttcggaa
     8941 aaagtgacta actatgacac aatttttttc acagtccctt ttttcacttg atttgattcg
     9001 taccagcgaa cttgacgaga actttcttgg tttggtaact atatggtatt cttttaacat
     9061 cctcgtttgc ttcttctaat ttatttatac aaagtcacac ttttttaaac atctgttctt
     9121 cgatacattt ctatttcttt taaacatcga taccaatatt ttgaacttaa gagtgcatac
     9181 caaatggatt catttactct tcgtcagtta cgaagataat caaaatctcc aacttcccta
     9241 cttatttcgt tttgagaatt atcgaagcaa tcttacataa ataactaaaa aacaaaaaac
     9301 cagaaaatca gtatactgat tttctggttt tacatggttt gttcaataaa aagctgttgg
     9361 aactgttaat attaaattat cgcatcgtta cgaattcttc cgctcctgtt ggatggatgg
     9421 ctactgtatt gtcaaagtct tctttagttg cacccatctt gatagccacg gcaaaacctt
     9481 gcagcatctc atcgacacca acaccaatag catgtaagcc gacgattctt tcttcttttc
     9541 cgacacagat caatttcatt tcgcattttt ggcgataatc atttaatgca aagtacattg
     9601 gggtaaagcg tgaacgataa actttcaatt cattttcgcc atatttttcc aatgcttctt
     9661 cttctgtcaa accaattgtt gcaattggtg gatgcgtaaa gacgactgtc ggaacaagtt
     9721 tatagtcaag ataagaatct ttctttccat taaataaacg ttctgataaa cgtctaccag
     9781 ctgcgattgc aacaggagtc agatctaatt taccgatcac atcaccaaca gcaaaaatat
     9841 gttcatccgt tgtattttgg tatttatcta ctttgataaa cccttttttg tccaattcca
     9901 catttgtatt ttccagacct aatttttcgg tattcggtac acgtccaccg gcaaaaagta
     9961 cacaatcacc agttaaggtt tcaccatttt caaatagcac cgtatattcg tcattgtttt
    10021 tagtaatttc tttagcaata tgatgtgcgt aagtttttat tccagcttct tggtacattt
    10081 ggatcaaatt gtccgaaagc attttatcaa acgttctaag tggtcgttct tttcgatatg
    10141 cccacatgac ttcactacct aaaccacgaa atacacctga aagttcagcc gcaatgtatc
    10201 cagcacctaa aacgattgct ctcttaggta actctgttaa ttcaaaaaat ccatttgaat
    10261 caattgcgta ttctccacca ggaatggtca ttttacttgc acggcctcca gtagcgatca
    10321 agattttagg agcacgatag gtttcaccgt ttacttcgat cgtttgacta tcgataaaag
    10381 tagcgtaacc ttttatagcc tcgacatgat tgctatctaa tcctctttga taagcaccgt
    10441 gtagaaaatc aatatatttt tctcgtcttt ctactagacc ggcgaaatca acatttttta
    10501 aatctgcttg gataccgtaa cttgaggcat ctcgttcaat tgtttccaaa atcgtacttg
    10561 cttgccacat aactttttta ggtacacaac cgacgttgac acatgttccg cccaattcat
    10621 tcgcttcaat cagcaaaact tttgcgccat gcatccctgc tctgtttgct gaagcaatac
    10681 cgccagagcc gccaccaatt acgatgtaat catatatttg cattttgttc ctccttattg
    10741 aagagatcaa tcaaaacctt tatttaacga tcctttttct acagaaaaca agtgtaacac
    10801 ttttcttgaa ttttgtatgc gaagatgctt aaaacaggga tatatcagct ttttccttat
    10861 ttacgttttc ggatcatatc tccaggtttc accggctgtg cgactggcat agttaaaatc
    10921 atcattggat ttggtgctcg gtcaatggat tcgccttctt cattatgcat aacttcaacg
    10981 gtttgactga aatgactgaa tcctggacca taaaattcga tttcatctcc tacagaaaac
    11041 aagtttctct gacgtatcgt agcaatctgt gttgcctcat cataagataa tacttcaccg
    11101 acaaatttat atactgggat tttacgacgt tcaccgaata attgttcgtt ttcagttggt
    11161 gtattgtagt aaaaacctgt agctaattct cgttgtgcta ctttccataa ctcgtcgatc
    11221 cattcttgct tgcagacata gttttcagga tcttccatat aactgtctac agccgcttta
    11281 tagacatttg acaccgtaga tacataatgg atcgatttca ttcttccttc gatcttgaag
    11341 ctgtctacgc cgttttcaat caattctgga atatgttcga tcattgacat atccactgca
    11401 ctcatcgaga attcttcttc cacttcgcct gtatcagtta aactgtttcg ttcttgacca
    11461 aaaggcatat cgaacaatcc atacttccag cgacaagatt gagaacatcc gccacggttt
    11521 gcatcccgca tcgacatatg gttggacaat gtgcatcgac cagaataaga gatacacatg
    11581 gcaccatgga taaatgcttc gatttcggta tccgtatttt tacgaatctc tgccacttcc
    11641 tccattgaaa cttcacgagc taaaacgaca cgttccaacc cttcttcttt ccagaattcc
    11701 aatgtctcaa aattagttgc tgaagcttga gtggataaat ggatcggcag acctggggct
    11761 tctgtcgcac aaatttcgat caaagctgga tcagaaacaa tcactgcaga aataccgaca
    11821 tcacgcaaac tgcggaaaaa ttcccctgct ccatcttcat ttccttcatg ggtgaccata
    11881 ttagcagcaa cgtatacctt cgcatcatgt tcttttgcaa aagcaactcc ttcagccatt
    11941 tcttcataag taaaattacc tgcacggctt cttaaaccat atgcattccc gccaatatat
    12001 actgcatctg ctccataatg gatcgcggtt tttaactttt ccagtgttcc tgctggcgct
    12061 aggatttctg gtcgtttcaa ttttcttttt actgtcattt ctttcatcat actccttatt
    12121 tgatagcaga aggatcaata taaaagaatc ctgtatctaa ttcacggttt tcaggatgca
    12181 atttactgat ttcgctagtc attttttccg ctttttcttg atcccagcta ccttctaaaa
    12241 tttgtttttt tgcttcggcg aatagtcgag tgatgtttac gaatttttcg cctggagtaa
    12301 ataatccgtc caatttccat gtacagtaat gatgctgata aagttcattc aattcattcg
    12361 agagattcag atcattgctg gcaaaaatat gtgtgccatg actatcttca taaatagaat
    12421 aatgtgtctc ttctttttta ggttccgaga taaaaagacc tctttcacga tctttttgtt
    12481 cgtcttgttt cgtatagtta tagtaattct gtagcagtgg acgtttggat tgatggatgc
    12541 atgtagcacc atacacaagg gtttctacag gaatatcgag tttttcttcc atcgccttca
    12601 tctcttcaaa aggaacttca cgagcaagta ctgctccaac tgcgcctttt ttcgcccaga
    12661 aattgatttg acgtgcgctc gttactaatg tttcagcatc ataaatatac ggtatacgca
    12721 attcaggatt ttttttcatc gtataaataa tacctgtatc accaactgtg atcacatcta
    12781 cgtttatttc ttttaaaaaa gccaaatatt caggtacatt tttcattttt tcaggatgaa
    12841 tgatcccatt tacagcaata ttcgcttttt taccatactt gtgtgctaat tctaccaatt
    12901 gtcgctgttc ttctcgtgta aatgaagcag gcagacgcaa tccaaattgc tcttcaccga
    12961 aatatagtgt atctgcacct gcagcaagca actgttctgc ttgttcaata gtttctactg
    13021 tggttatgag ttcgatcata attttctcct cctacaactt cataatagta gcatagctct
    13081 aaaaactttc caatacttct tctatttaaa gtcggatttt tgaaaattat ttcacaaaaa
    13141 atcaaaataa agttcgatat attctgtcca aatataaaaa gagattgtga caaaaatctt
    13201 gtcacaacct cttaatcaag tcttactatt ataaaaattc agctacacag gccaagtaac
    13261 tatagggaac ctactgtttc ctttttaggt ccgcgaacat tcaatgtgat cttacctttt
    13321 gaagcaccta ctgttacgtg gtcacctaaa cgaatttctc cgccaagcaa agcctcgctc
    13381 aatcgatctt caatttcttt ttgaagtgcg cgacggattg gacgtgcacc atattcagga
    13441 tcaaatccag ctttcccgat cacatcgatt gcagatggtg tgattttcac ttgaatatct
    13501 tgttctttca atcgtttgat aatcgctttg ctcatgattt ggacgattgt atggatttca
    13561 tctttactca atgaatggaa gacgacagtc tcatcgattc gattcaagaa ttcaggtcgg
    13621 aaagctttct ttaactcttc taagatacgt ttttgcatgg ctttgtgatc tttagtaaca
    13681 tcttggacat tgaatccgac atttttttct tctcgaattt gtgtcgctcc gatatttgaa
    13741 gtcataatca tgattgtatt tctaaagtcc acttttctac ctttagaatc tgttaaatga
    13801 ccatcatcca atacttgcag aagtaaattg aaaacgtctg gatgtgcttt ctccacttca
    13861 tctaagagaa tcactgaata tggtttttga cgaatttttt ctgtcaactg tccaccttca
    13921 tcatacccta cgtatcctgg aggagacccg attaatcggc ttgtactgta tttttccata
    13981 aattctgaca tatcaacacg gatcagggca tcttcacttc caaacatgac ttctgaaagt
    14041 gctttggcca attctgtttt tccgacacca gttggtccaa ggaacatgaa tgaaccaatt
    14101 ggacgatcag gatctttcaa tccgcttcgt gcacggcgga tcgcacgtga aactgctttg
    14161 acagcctcat cttgaccaac gacacgttca tgcagaagtc cttccagttc taacaagcgt
    14221 tcgctttctt ttttctccaa ctgctgtaga gggacaccag tccactccga tacaactgta
    14281 gcaacatctt cttctgttac acgatcagaa taaccttgct cctgttttgc ttcaattgca
    14341 gaaacttttt gcagcttttt acgtagtgct ttttcttgtc tgcgtaattg agcagcattt
    14401 tcaaagtctt gtttttggat cgctgcttcc ttttcttgta ctagttcatc gatttctagt
    14461 ttgatcacag ttgattttgt taagtgatcg gtttgatcca aacggacttt cgctgctgat
    14521 tcatcgatca aatcaattgc tttatcgggt agttgacgag aagtgatata acgaacagaa
    14581 agattgactg ctgctcgtac agcttcatct gtgatctcca ctccatggtg ctcttcatat
    14641 cttgtacgta atccttgaag aatcacttct gcttcttcag gagttggctc atctacttga
    14701 atgcgagcaa aacgtcgctc taatgcagaa tctttttcga tatatttttg atattcatct
    14761 agggtcgttg ctccgatcgt ttgtaattct cctcgagcta acgccggttt caagatattc
    14821 gaagcatcaa ttgctccttc tgctccacct gcaccaatta aggtatgcaa ttcatcaatg
    14881 aataagatta cttgaccatc attatagatt tcgtcgatga cctttttcat tcgatcttca
    14941 aattcaccgc gatatttcgt accagcaacc aaagatccca tatcaagcat catcaggcgc
    15001 ttttcttgca tgtcttctgg cacttcacct aaaatgattt tttgagctaa cccttcagca
    15061 atggctgttt tgcctacacc aggttcaccc accagtacag ggttattctt tgtccgtcgg
    15121 ctaagaatct ggataagccg tttcacttct ctcgaacgac caacaactgg gtccagcttg
    15181 ttttcttttg ctaatttcgt caaatcacgt gctaatgaat ctagcgtagg tgttccttgc
    15241 ggtgtttgcc gtttatcttg tacatttaca tttctacgac gattcattcc ttttccagca
    15301 gaatcaccag ctagccccat tttttgtttc agaacttgac gggcttttga aaggctgata
    15361 cctaagttga tcatgattcg agtagccatg atactttcat cttttaataa gctcatcaaa
    15421 atatgttctg ttccaacttt ttgagaacca gttttcttca cttcgctgct agctaaagca
    15481 aaaacttgtt tcattcttgg tgaatatgga agaaagactc ctttagggta agaacggata
    15541 ccaccataac caatcagatg ttcaatttct tcataaattt ccgtttcatt caaatccatt
    15601 tcacgtaata cttttccagc aattccattt tgctcgacca ctaaggctag taaaacatgt
    15661 tctgaactaa ctgattgatg tttcaaccgt tttgcttctt cttgtgcaat ttctaatact
    15721 gcttgggctc tttcagtaaa aagttcttcc atctaatctc acttcccatc ttcataactt
    15781 aaacgttcca gaaatgctcg gagaatccga gcacgtgtat gatcttcata ttcattgaaa
    15841 ttcaatgtgt tttttgcaat tgcactcaac atcaagtttc cttctttttt tgtaattatt
    15901 tggtcttcat aaagtttttg aataatagca aaagcatttt tctcactgat tgtatcatca
    15961 aataactgat ttatctgctc aagtaattgt tttttatctg aaatccttac ttttgcaatt
    16021 cgtatataac caccaccacc acgtttgctt tctactagat aaccacgttg gatggtaaaa
    16081 cgggtattaa tcacatagtt gatttgtgaa ggaacacagt taaagaggtc tgccatttca
    16141 atccttcgaa tctcgatcat ttcactattt tccagaattt tctttatata tgattcaatt
    16201 aaatccgagg tattctgatg tgccatctta ttcattccct ttgactaata ttgaccttaa
    16261 ttataacgaa tttgataata gaaagaaaga agaacgcttt ttgttaaata aatcctttag
    16321 aatcaacaaa aaaaaatacg gaatatacta ttccgtatcg acgcgcccaa gaggagtcga
    16381 acccctaacc ttttgatccg tagtcaaaca ctctatccag ttgagctatg ggcgcatatt
    16441 caatttaaaa aaattataaa tcatttgaaa acaaaaagca agataaaaaa aatcgggaag
    16501 acaggattcg aacctgcgac cccttggtcc caaaccaagt gctctaccaa gctgagctac
    16561 ttcccgttta aaaaataaaa aagac
//
LOCUS       DARPZJ010000053        16527 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.056, whole genome shotgun sequence.
ACCESSION   DARPZJ010000053 DARPZJ010000000
VERSION     DARPZJ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.056"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(142..417)
                     /locus_tag="SLE23_002132"
     CDS             complement(142..417)
                     /locus_tag="SLE23_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEI8469012.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(660..1970)
                     /gene="der"
                     /locus_tag="SLE23_002133"
     CDS             complement(660..1970)
                     /gene="der"
                     /locus_tag="SLE23_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEI8469013.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2152..3381)
                     /gene="rpsA"
                     /locus_tag="SLE23_002134"
     CDS             complement(2152..3381)
                     /gene="rpsA"
                     /locus_tag="SLE23_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEI8469014.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3516..4196)
                     /locus_tag="SLE23_002135"
     CDS             complement(3516..4196)
                     /locus_tag="SLE23_002135"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEI8469015.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4245..4880)
                     /locus_tag="SLE23_002136"
     CDS             complement(4245..4880)
                     /locus_tag="SLE23_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8469016.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4946..6349)
                     /locus_tag="SLE23_002137"
     CDS             complement(4946..6349)
                     /locus_tag="SLE23_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HEI8469017.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6336..7367)
                     /locus_tag="SLE23_002138"
     CDS             complement(6336..7367)
                     /locus_tag="SLE23_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8469018.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7398..7619
                     /locus_tag="SLE23_002139"
     CDS             7398..7619
                     /locus_tag="SLE23_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEI8469019.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7784..8521)
                     /locus_tag="SLE23_002140"
     CDS             complement(7784..8521)
                     /locus_tag="SLE23_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEI8469020.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8674..10014)
                     /locus_tag="SLE23_002141"
     CDS             complement(8674..10014)
                     /locus_tag="SLE23_002141"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HEI8469021.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10251..11774)
                     /locus_tag="SLE23_002142"
     CDS             complement(10251..11774)
                     /locus_tag="SLE23_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEI8469022.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12152..12763)
                     /locus_tag="SLE23_002143"
     CDS             complement(12152..12763)
                     /locus_tag="SLE23_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8469023.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12886..13011)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13093..13809)
                     /locus_tag="SLE23_002144"
     CDS             complement(13093..13809)
                     /locus_tag="SLE23_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEI8469024.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="SLE23_002145"
     CDS             complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="SLE23_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HEI8469025.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14368..15165)
                     /locus_tag="SLE23_002146"
     CDS             complement(14368..15165)
                     /locus_tag="SLE23_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEI8469026.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15135..15506)
                     /locus_tag="SLE23_002147"
     CDS             complement(15135..15506)
                     /locus_tag="SLE23_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEI8469027.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="SLE23_002148"
     CDS             complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="SLE23_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEI8469028.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4645 a         3576 c         2798 g         5508 t
ORIGIN      
        1 taaaaattaa ataaaataca tgtgttttct atgtatgaca tacggattcg gaatctctgt
       61 ctcttattta ttccttttct gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc
      121 acaagcgctt tttcaactgt cttatttaac agcgtctttt aatgctttac ctggtttgaa
      181 tgcaggtact ttgctagctg gaatttcgat ttcttcacca gtttgtgggt tacgaccttt
      241 gcgagctgcg cgttcgcgaa cttcaaagtt accaaaaccg attaattgaa ctttttcgcc
      301 gttagctaaa gcatcttgaa tagttgaaaa tacagcatct actgctgcag ttgcatcttt
      361 tttagttaaa tcagtagctg aagcaacttt ttcgattaat tctgctttgt ttgccatgga
      421 tagattcacc tcctccacaa gagatatgat agaaatatca tttagttaaa actttctgag
      481 tggtccagaa gtttaaaaag aaatattgat taacttcaat attctgttat cacgatatca
      541 tatgaaccgc ttaatagcaa ggtttttacc aattttcaca tgcttttttt agtcatagaa
      601 acgtaacaaa cgaaactgtc tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc
      661 tattttctcc tacgagggat aattcggatg gacgtccctt caaaagtaaa tgcttttctg
      721 atttgatttt ctaagaaacg ttcataagaa aaatgcatca attcctcttc attgacaaaa
      781 acgacaaatg taggtggttt gacagcgact tgtgtagcat aaaaaatctt caggcgtttt
      841 cctttatctg ttggtgttgg attgattgct acagcatcca taatgatatc attcaacaca
      901 gccgaagaga tacgaagatt ctggttcata cttacttgtt cgatcatttc aggcagacgt
      961 tccaaccgtt gtttagtcac tgcagaaaca aaaacgattg gagcgtaatc aagataccgg
     1021 aattcatcac gaatctcttg ttcgaaatca cgcattgtat tggtttcttt ctttacaaga
     1081 tcccatttat tcacgacgat aataattcca cgaccagctt catgggcgta acccgctact
     1141 cgcttgtctt gttcccgaat cccttcttca gcattcagta ccatcaaaac gatatcagaa
     1201 cggtcaatgg cacgcattgc acgcatcacg ctgtattttt cagtattttc gtatactttt
     1261 ccgcgtttac gcataccagc tgtatctatc attaagaatt tctgaccact ttcagaaacg
     1321 aagtgggtgt cgattgcgtc tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct
     1381 tctcctaaaa tcgcattgat caaagaggat ttaccaacat ttgggcgacc aatcaaacta
     1441 aacttaatcg tgtcgtcgtc ctcttcttca gtctcttcag agaaatactt cactgcttca
     1501 tctaaaatat caccaatccc tagtccatgg cttcctgaaa caggataagg atcgcctagc
     1561 cctaaggaat aaaattcata gatatcgttt ctcatttctg gattatctac tttattgact
     1621 gctaaaatca ctggtttatt acttctgtat aaaattttcg caaccatctc atctgcgtct
     1681 gtcacgcctt cgcgtccgct gactacacaa atgattacat ctgcttcttc aatcgcgatt
     1741 tctgcttgat gcttgatctg atccataaaa ggttcatcgc caagatcaat tccgcctgtg
     1801 tcgatcacgc tgaattctcg acctaaccat tcaccttttg cataaatacg atcacgagtt
     1861 actccaggag tatcttcgac aatcgagata cgctcaccag cgatgcggtt aaaaatcgta
     1921 gacttaccga cgttcgggcg gccaacgatt gcaattgttg gatttgccat attatttcct
     1981 cctcacaagt ttccaatctc acttagttta acgaatgcat tgccaacttt caagcataga
     2041 ttgtcaatta aacgaagtat ttttattcct tattgaaata ctaatcgctt ttcaaaagaa
     2101 aaactgagac aaaagcagct gctttcatct cagtcacaga tacaaaatca attatttttc
     2161 agaatcatcg gttgcttttt cttctacttc ttctttcaac gcatcaccta aaatgtctcc
     2221 catagtaaat ccagtatttt cttctggtaa ttcataagac tcaacatttt ttggttcttc
     2281 ttctgaagct ggtttttctt ctaaagcttt gatactcaat gcaatacgat gttcttctgg
     2341 atggatctct aatactttca ctttcacttc gtcaccttca tgaagcactt catgtggtgt
     2401 cgcaatatgt ttatgtgaaa tttgagagat atggactagc ccttctactc cagggaacac
     2461 ttcaacaaag gcaccgaagc ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac
     2521 tggagctttt gtatcgattt ctgaccaagg tccaggctgt gtgtctttga ttgacaagga
     2581 aacacgttct tgttcaggat tgatagacaa cactttgaca tttacatcat cattgacagc
     2641 caatacatca cttggttttg ctacatgact atgtgaaatc tctgagacat ggactagacc
     2701 gtcaattccg cctaggtcga caaatgcgcc aaaatcagta agacgtgcaa cacgtccact
     2761 gagaacatct ccctcatgga tagttgaaag aatttctttt ttcttttctt ctctttcgtt
     2821 ttccactacc gctttatgcg ataagatcaa acgattttct gatggttcga tttcgatgat
     2881 tttaaagctc aatgttttgc ctttatagtc tgaaaagtct gcaacaaaat gatcttccac
     2941 cattgatgca gggacaaaac cacgtacacc gacgtcaacg actaaaccgc ctttgacaac
     3001 atttgtaaca ggtgcttcga tgaccttgcc ctcttggaaa tctctttcga tatcttccca
     3061 aactttttta gcatctaaac ggcgttttga aagtaggtag ctgccgtttt ctttatcttt
     3121 gccgatcgta ctgataacga ctaaatctaa tacatcaccg acttttacta cttcgctgat
     3181 atcttctacc ggcaaagttg ataattcttt tgccggaacg actccttcaa ctccagcccc
     3241 ttcgattccg acaatcactt gtttgtcttc aatgactaaa acttcgccct taacaacatc
     3301 gccaactttt acttcttgta cgcttttcat tgcgtcttcc attgactggt tgttctcttg
     3361 attttgatca aattctgtca taacacttgt cctcctaacc aacattctgc cgtaagtacg
     3421 gtactgtttt tagtttaatt gattattcaa aaaaaataaa gcgatttcgt tcgttttcct
     3481 tgaaaaaaca attgtttttc attttttttc ttaatttaaa aaagaagata accttttttc
     3541 aaaacaacag cttttattgc tgcaacgact tctggaatcg atttgccagt cgtatcgata
     3601 cgaacagcat cctctgcttg cttcagcgga gagacgtccc ttgttgaatc ataatggtct
     3661 ctttcctgta tctctttcgt cagtgtttca agatcagtcg gaattccttt ttcttggttc
     3721 tctttgaaac gtctttctgc acgctcactt acgcttgcta ctaaaaagat tttcacttct
     3781 gcattcggta atacagctgt cccgatgtct cttccgtcca tgacaacgcc accgcgttcc
     3841 cctatttttc gttggacagc aactaattct tctctgactt ttccatgtgc agagacttca
     3901 gaaacagctt ttgtgacatc tggttgacgg atttctaaag tcacatcttt tgatgctatg
     3961 aatacatgct gtccatcttc ttgttgcgaa aaagagatag gatacttttt gatcagcgaa
     4021 actagccctt cttcatctga aaaagataca ttgttcgtaa tagctaaata agttactgcg
     4081 cgatacatgg caccggtatc tgtataaata taattcaatt cttttgctaa tatcttggca
     4141 acggtacttt tcccagatga agcaggcccg tcgattgcaa tactgatttg tgtcatgata
     4201 taactccttt ttctcagaaa aaaagccgca aagcgcggct attattattt aattcttaat
     4261 tcttgaccag ggtaaagcat aaagttgttt ggatctaagc cattcaattc aaacaattga
     4321 tcagtggtga tccctgcacg ctcagccact tgttttggac cttcgcctgc ttgaacagtc
     4381 gttgttgaac cggctgcagc tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa
     4441 tcccctgctt gataagttgc ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg
     4501 ctttctgacg ttacacctgt atcttgagac acagtagatt cttccgcgat tgtactagat
     4561 tctactgttg aagtctcagt tgactcctct tttgttgtac ttgtagaact ttctactact
     4621 gatgtcgaag tttcagaaga agttgctgct gttgcattgt tgcttgatcc atttctgatc
     4681 cagaaataag cacctgctgg aatagcgata cataagacca gtaaaatcaa aaatagcgaa
     4741 agaaataatg tatttccttt cttttgttgt ctctgagaac ttcttgatga aacttcatca
     4801 tctgtatcgt agattggttg ttcccatggt tcttgtgttt cgttattttc tgtagattga
     4861 tgtctatctt ttctgctcac tgttttacct cctaaactct atcgtgtgta ttataccata
     4921 ggaaaaagtg tcttgtccta aaaaatcaat gttccatgtt ttttttaaat aaatttagta
     4981 aaatcgtttc ccaatgaagt tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt
     5041 ctgcttttgc tccatcaata tcacaacaat tctgcggctt ttcggagagt ttttcgccaa
     5101 aataagctaa gatgaatttt ctgcggcagt tttcttcatt aatatagcga agcatctgct
     5161 gcaggcggaa ttctttttct ttttcctgac gtttgagccg ttccacccaa ttttctggtt
     5221 tttcagactg ctggatcagc tccatccatt ttttttgcag ctcatcaaag ggagcttgct
     5281 ttgtggcata ttccaaataa agctcaaaac tttgtcgctg ttctctagaa agttgattaa
     5341 agaaataatg gatacgttca tccccacttt gataaaaaag aattgctgca ctttcttcct
     5401 gatctctgcc tgctcgaccg atttcttgta catagttttc tagactgtct ggcaaatcat
     5461 aatggaccac ataacggata tcagatttat cgatccccat accaaatgca ttcgtagcaa
     5521 tgagaaactg cagctgattt tttacaaact gctgttgaag ttgtcttctt tgagctgcat
     5581 caagaccacc gtgatagtat ccaactgtaa aacgttccct gaataaatga tacaatcgtt
     5641 cgacttcttt ttttgttgca caataaatga ttgccgctcc ttgtgctctt tccatgaagt
     5701 gttcaagttc ttgttctttt tgctgcgttt tccgaacaaa aagcgagata ttttgccgat
     5761 tgactgattg tctgatctct tttggtggtc gatcaaatag tacatgacgt atatctcttg
     5821 ctactaaatc tgttgctgtc gccgttagtg ccagtgtgac cgggtttcct aaaagctttc
     5881 ggatttttcc taactgttga tattctggac ggaaatcaac tccccattga gacacgcaat
     5941 gagcctcatc tactacatat aacgcaatat tttgtttttt cagatgctct aaaagagaag
     6001 gattagtcaa catttcggga ctcaaaaaca aaaatttata ttgcgataga tgacggagga
     6061 cgtatcttct ttcagattgc gaaagtaaac tattgaaagc agctactcgt ttctcccctc
     6121 gtttttgtaa ttgcgtcact tgatcttcca ttagagaaag cagcggtgac acgatgatga
     6181 ccagaccttc cattaaatac cccgtcaatt gatagcaaag gctttttccc gttcctgtag
     6241 gcaaaatagc gagagtatct tctccatcaa gcaacgcctg aataatttct tcttggccgg
     6301 gacgaaatga atcaaatcca aaatattttt ttaattcatt tattaacatt ctgtatcgct
     6361 tcctttctca atagatagat ttgatacaaa cgaaattctc cataatctaa ttgtccatct
     6421 acattccatt cgctaaagcg ccactctcgc acggaatcct tatttggttc caaacgttcg
     6481 attgtttctg cagagagaat ccactcgtat ggaaaatcat caaaaaacaa ggcccactca
     6541 ataagatgat ctgttactgt tcctcttttt aaatgacgga ttgccatgat ctggtcaatt
     6601 gtctgaccat tcataaacat ctgcttggtg atcatcatgc tttgattgaa attttgctgt
     6661 aataatgaat cgatcaaagc gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac
     6721 aaaaggtgga tacatctgct ttgttgcaga taaacctctg actcatcatt gttttttgcc
     6781 agctgataag gaagcagccc tgttcgctca tttccagata attggttagc taaaaaatct
     6841 gctgcttctt ctggtatctc cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc
     6901 aaaatttcac gtggcaattg gctttcacta agccattttt ttagttggaa agtataaaaa
     6961 ggacttgtct ctgctggaag atagtcttga atacccgttg ccagattaga aattacttga
     7021 acagcaaatt taatgagccg ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc
     7081 aaaccagtat gttctatttg atgttcggac aacatatcag cccctgcagg cgttagcttt
     7141 gcttcatttt catttatttc gatccaacct tgctgcgcaa ttttttgcaa aatttgataa
     7201 aacttatcct gcttcaattc tggaaaactg ttatggataa acaaaagttc gtgggtaaat
     7261 ccataaataa gtactgaagt cgttcgtttt cccacaagga gttggtaaag agaactaatc
     7321 cgcagcttgt gtcctgatga aaatagcgat aaaataaaaa caatcatatt attctcctta
     7381 agttaggatg gttagaaatg tcactactat gtaaacttgt acctgaacgc tgtattgcat
     7441 gcggtctttg tcaaatcgaa gcgccagata ttttcgatta tgatgaagaa ggaatcgttt
     7501 tatttgccca agaaccagag gctcatcaac agttcgtgat gccggaagaa gaaacatatg
     7561 taaaaaaagc gtatcaaaaa tgtccagttc gagcgatttt attagaaaat aaaatataaa
     7621 tataaacgaa actttaaaaa cgtacactaa gttctctaaa cttgaaaata agccgggatc
     7681 tgtttctctt gttccgtgaa atcccgactt attttgaaag attcatttgc tatctatagt
     7741 taattgacta gttttttcac ggaccctata ggacccattt atattatttc aactttttca
     7801 gccagttttc caatgtattg acgatcacag tttgctggtc tgcgttagaa atttctgcct
     7861 ctccatctcc tttttgctca ccatagctgc caaaacctcc atgatttccg ccattgattg
     7921 atacatactc tgttctttcc ggtaaatact gcttagcttc ttgataagct tcctgattca
     7981 atactttatc ttttgtcgcc gtgatcgata aaacaggaac agctgattct gtcaatgttc
     8041 cttttttgtc gggataactt gccatgaaga ataccccttt taaatgtttg tctgaatgat
     8101 tcttattgac ataacgactt gccattacgc cacctaatga atggccaccg atcacataat
     8161 cggaatttgg aaaatcttct ttgaccttat ccgctttgtt tccgcccatc actgctagat
     8221 caagtggcat tttgacaata gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa
     8281 tactataact ttctggctct acgagagcac caggataaaa aataagtaat ggagactttc
     8341 catgattctt tttctctcct tcaaaaaata agtaatcttc tttgtttttt ccttctttta
     8401 ccaacacttg cgcttctgac gatggttcgt acgtattttg ctgtatatag taataaccgg
     8461 ctccaccgag taatcctaaa atgatgacta agccaattag tattcgtcta aatattttca
     8521 ctttctccca ccttttctat ctgagtgacc cctttttctt aatcaagtat gattatacct
     8581 taaaaaaata agagagaaat gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc
     8641 atttgaatat ccgccctttt tgtatgttta tttttattta gcacataaac gatacacagc
     8701 ttctgcataa atttccattg ctttatacat actacttaat tcccatcgtt cattcgcctg
     8761 gtgcataaag tcaggagtat cagggaacat cgcaccgaat gccacacact ggttcatcgt
     8821 acgagcaaaa gtagcgccgc ctgatacaaa cggttcagtc atgtctccag taatatcgcg
     8881 atatgtcccc aatagatttt tcactaactc actgtctagt ggcacgtata atgaatcaag
     8941 gaagtcaaat tcttcataag tcaacccata tttttctgct gttttagtta atttagctac
     9001 taaatcatct ttcttgaatg taacagggat tctcatatct acaccgattt ttgtttgttc
     9061 tggtgtgatt tccaaacttg caaagttcat cgttagctcg ccggattgtt catcttctgt
     9121 tttgcccacg acagcttcac cagttgcatt ttcttgaact aattttccta agaaattgat
     9181 tgggccaaaa tcaaatactt ctgaaagagc aattgccaga cgagaaatag cattcactcc
     9241 ttgtgctgca tctttcgcgt ggatactttt accaagaacg acgatgcctt caccttgttc
     9301 ttcgaaatcg aattcgtgtt ttttcaatgc ttcttttact tcagaaagct tttctccaga
     9361 gtaaggagct gcatcaggaa caacattcaa cgctcctcca gcttttacag aaaactcgtt
     9421 cgttcctggt cctgtcaagt aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa
     9481 ttcagcatct ggcgcaaatc cttgcgtaat tccttcttct ttttcgttat atttttctaa
     9541 acaacgccat aaattttctt catctgtacc aaagataaaa cgaatacgtg tcttgaattc
     9601 cacgccagca tcaatcaaag ctttgacggc atacattgcc gcaatagaag gacctttgtc
     9661 atcttgggat ccgcgaccaa ctaaccagcc gtcttttata gttggatcga atggttttgt
     9721 ttcccaatta ttttcgtccc ctgctggaac aacgtccata tgacacaaga taccgaataa
     9781 ttcatctcca gagccaatct ctgaataacc gtaatagcct tctggatctt taaatgttct
     9841 aaatcctagc ttttcactga tttccaatac tttatccaaa gcttcaatca cttttttacc
     9901 gaagggatgt ccttgtcctg aatctgcttc atctagtacg gaaggaattc ggatcaattc
     9961 gctcaatgat tctaatgctt gttcatgatg ttgttctgtc acaaattttt tcatgatatt
    10021 atcctcctaa tatgttaaaa agggtcatgt caaattcctc cgacacaacc tcttcttctc
    10081 aaataatgac gttttaagcc tgctccatca gcaagcagaa tgttcttaac aaatgatgaa
    10141 agaaaaaaca ctcactgaat ggagctattg acttgtccac gtgcttatcg atagccgttt
    10201 atcggtttct tcattcttat gatagacctt gtacttgtat ttgtctaggt ttagaacatt
    10261 gctgctacac ctaggatcac acagatggct acaaataata tcgcaattaa tttaccggta
    10321 aatttccacc acactgaaac atcgaaacga gcaattgcta cagcacccat tacgatagca
    10381 gatgttggtg taattaagtt tactaaacca gatgcagatt gataagcagt gattactaaa
    10441 tccttaccga cgccggcaaa ttcacccata ggtcccatga ttcccattgt tgcagcagct
    10501 aagccggaag ttgaaggaat caagaatgac atagggatat agaaaataaa tgtaataatg
    10561 atgaatacac ttgaagataa tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct
    10621 gtgattaatc cattgttcat aaccacttgg ataccacgag caacagctac tacgattgct
    10681 acaccgatca aatcagaagc accagctaaa aattcagaga caaattcaga ctctttcatg
    10741 ccataagtga ttgctactac gatggacatt actaagaata acatagtaat ttctgggaag
    10801 taccagtcac ctaatggaag catgctttta cctagaaccg tacctagtac cggaaggttt
    10861 gttaaccagt ttgtcaatga ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga
    10921 atcaaactga tgatcatgat accaaaagta ataaagaaca atacattaac atgtttttgt
    10981 tttttcgtga ttacttcttg acgaccgatt gcttcaatat cgaaatgctt catatcttct
    11041 ttacgttggt tgtatactaa tgattttgtt ggatcttttt cgatctttga tgcataacga
    11101 tacacatata caatagaaat agctaacaaa ataacgaaca tcaagaatcg aagaccaata
    11161 ccttcaccca tcgaaatccc aacagcttgt gaagctacgc ctgttgcaaa aggatttacc
    11221 gttgaagcta gacagcctac ttgagaccct actaatacga ttgctacagc tactactgta
    11281 tcaaagccta cagccatcat gactgggatc agtaaagcat agaatggaat cgtttcttct
    11341 gccattccgt aagtagagcc gcctaatgca aataacagca tcaatactgg aataagcatt
    11401 ttttcttttc ctttgaattt cttcacaact gaagcaatcc cggcatctag tgcccctgtt
    11461 ttgttgataa tacctaaaaa tccaccaaca accaaaatga agaaagagat tgggattgca
    11521 gcaggtgttt ctttagttag ctcccccgct ggtacaccta gcatcccatt gattggcgcc
    11581 atgaaaatat cccacagccc ttgaggattt tgttgtactc gttcatatga tccagcgacg
    11641 atgttgcctg catcgtctac actatagtgc ccagctggta taaaccaagt aagtacagcg
    11701 attactgcaa taataataaa taagaccgta tacgctgaag gcatttgaaa ttttttcttt
    11761 tttgtttgtt ccatcttctt cttcctttct tttccgttag agacaacaat tttggctcta
    11821 atgttatttt atcaaaaaga gtatcagaac aaaaataata acacgcattt tgtaaaactt
    11881 ttgttcaaaa agttcgtttt tccctattcc ctcctctttt ttcaggtttt taaagctttc
    11941 ttctttttca ttgtagcgtt tccttttttt tataaacaaa cattttcgtc ttttaaaagg
    12001 agaagaattt cacatttgca aagaattgat tgatttttat gcataaatca aaaaaatact
    12061 caaaacaaac aaataaaacg tttacattat tgcatgtctt gtattttttt ccaaaaaaaa
    12121 agaccaagaa atttcttgat ctttttgata tttatttgac tgctgtatga cgttgttcga
    12181 actgatgttg ttttcgactt aaccatggaa gaagttgcgc atgcagcact aaaaagacag
    12241 cactcacgat gaatcctttg atcaagttga aaggaacgat cccaatcagt acatagtttg
    12301 ctaaagacat gcccagcatc tgtgttgcgt tcagccctaa aaacattaag taaagaggcg
    12361 taataacgaa ataatttgcg atactcataa aaatagttag agcgatggtt cctgtaatga
    12421 cacctaaaaa tttgtttctt cctttatgct gtttctttac actaaagaaa taataaatcg
    12481 ggaatgtaaa gatcgttgtt gataagaaac tagcagtgtc tcctaccaaa ttatccggag
    12541 aaaaacctgt agtcagcaga tgtaatactg aacgcaagaa cgctgttgca actccggccg
    12601 ctggaccgaa taagaacatg ctgatcaata ccgagatatc actaaaatcg atcttcaaaa
    12661 aactaaaagc cggcatgatc ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa
    12721 acatcgctac tgcaaccatt ttctgtacac gggtgttctt catttgaaat cctcctgtta
    12781 ggactcctct tcagcgaact ttttgacgtt tctctccaaa tgaaaaaact ctattttcca
    12841 gggaaaatag agttagagtt atttgatcaa gcgtcgtcaa ataagctcta tcttctttat
    12901 ccagactata ctgtcggtat cggaatttca ccgattcagc tatttttttg caaaataggt
    12961 cgtggactat aaccaccggt cgggaatttc accctgcccc tgaagacgaa ccttatataa
    13021 tttttgttta catattcatt atacatatct attcaaaaaa cgcaacatct aacacttata
    13081 aaaagtaagt gttcattttg agtggttcag caaactgctg acttcttttt tgttcagttc
    13141 acggtaatcc ccaggacgta ggccttgtaa agtcagatct ccgtattttt cacgttttag
    13201 tttttgcaca ggaagaccaa ctgcttgaag catatttttc acttgatgat tacgtccttc
    13261 gtggatcgtc aattccacga tactgtggtt tgtcttagga tccactgata aaatttggaa
    13321 tttagctgga gatgtttttc gtccttcgat ctttattcct tttgtcaaag gtgcaagcat
    13381 cgattttgta gcgatccctt ttacctttgc aacgtaaact ttatccactt catgttttgg
    13441 atgtgtcagg cgctgagcaa aatctccatc atttgtcagt agcaagatcc ccgaagtatc
    13501 gtaatccagt cgacctacag gatagatacg ttcttttacc atcggcaaaa gatccgtaac
    13561 aacttttctt cctttgtcat ctgcaacagc agaaataact cctttaggtt tgtacaataa
    13621 atagtaaccg tattcttctt gataaattgg gacttcatcc acttccacag tgtcatgttt
    13681 cccaactttt atccctaatt cccttacaac ttgtccgttt acttttacac gtcctgcaag
    13741 gatgaattct tctgcttttc gacgagaagt gatgccagcg tgggcaatta ctttctgcaa
    13801 tctctccatt acaattattc tcctttattc attccatcaa agaatagatc tggtgacacg
    13861 tcttcttcaa gtgaaatttc catttcttgt gtatcaggca gttcttctaa tgatttcaaa
    13921 ccaaaataat ctaagaagta gccagttgtt ccatataata tcggccgacc tggtccttct
    13981 actctacctt tttcttcaat cagtttatgg gcagctagac gctgtaccgc tcctgaaacc
    14041 tgaactcctc gaatctgctc gatttcagct cttgtgattg gctgtttata agcgatgatt
    14101 gctaaggttt cgacggcggc ttgagataat gtgtttgatg tcccttgcgc atatcgctta
    14161 agtaagggag ccagctcttt tttagtcgtt aatacataat ggctttccgt ttcaaaaata
    14221 tgcaaagctg agtgcgagtt ttgagtgtaa gattctttta attctttcac taaacttgtg
    14281 acttctgctt cgctgagatt taacagtccg cttaattctt cattactgat cccttcctcg
    14341 ccaacaataa aaagaagggc ttcaagttca cttaatttcg tcatgttcgg tatctcctac
    14401 tgctggataa agcataattg attcatagtt ttctttttgt tgcgcaatga tctgcccttt
    14461 tttcatcaat tctagcaaag ccataaaagt agtgacaact tcacttttag aaggtgactc
    14521 aaaaaaagaa tcgaaagtac agccatgcgc atttcttttt atacgctctt cgataaatac
    14581 cattcgttct tcgatcgttg tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa
    14641 tttcttacgt tctaagattt tctgcatggc acggatcaaa tcgatttttt tgacttgtcc
    14701 tcgcttcaac ggcttttcag catccgctaa cccatcgatg ttcataggtt cttttgtgta
    14761 ataaagactt cgttcctctg ctttttctgt cagtctttca gctgcatatt tatatttacg
    14821 gtattctaaa agctgagtga ccaattcttc tcgaggatct tcttcccata attcttcatc
    14881 gtctgtgccg aattcttgga caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc
    14941 agccatcact aagtattctc ctgcaacagc tagctcgagt gttttcattg tatggatata
    15001 attcatatat tgctccgtga tcgtagcgat cggtatatca tatatatcga tttccatttg
    15061 ctgaatcaga tgaagcagca gatcgagagg accctcgaat acatctaatt taatattgat
    15121 ctccgtcaac tcattcactc tttcttcttt ttctttgcta gccattttcc aatgtaaggc
    15181 tctgtgattt cagttgcacg gatggagaca tccgggtact tttcctgtaa ttcatctaac
    15241 atttgaaagc ccatattctc accgcgataa gacggattca aagaaatgtc atggatgatc
    15301 agctgatcgt tcgttgccca gtaaatacca ataatccctt gaatgttggt tgaaccttct
    15361 ggcgtaaaga aaaaaagttc ataatcgtct tcagattcgt acgtatcaat ctccttcaac
    15421 aaagaagttt tacctgtcag tttcttatgg aaactcaata gtcccatagc aattttacgg
    15481 ttttctttcc ggtaatgtgt taacatcttc tcaccttcct atgactaagc ccttggaaaa
    15541 tgctgcttat aaacatccgt cattcttttc ttcgtgatat gtgtataaat ctgagtcgta
    15601 gagatatccg cgtgacctaa caattcctgt actgtccgca aatcagctcc attttctagc
    15661 agatgtgtgg caaagctatg ccgcagcgta tgtggtgtta cttctttgta aatcccagcc
    15721 tctcgtacta actgcttcag atttttccag attccttgcc gagaaagacc tttcccatga
    15781 ttattgacaa atacatgcat ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct
    15841 aagtagcgtt ccagccattg gatcgcataa tcacctaaag gaatgatccg ctctttatct
    15901 ccttttccaa ctgtctgtac cagtccaaga gaaagatgaa gatctcccaa tttcaatcca
    15961 atcaattcac tgacgcgcat cccagtagca tacatgactt ccaagattgc acgatctctt
    16021 atccctaacg tttttgtcgt atcaggtgct tcaatcagct tttctacttc tgtcagagtc
    16081 aatgtacttg gtaatttctg tgctttcttc ggcgtatcga tatgttgcat cggatcatga
    16141 tcagtgatac gctcttgccg taaaaactga tggaatcttc tgagacttga gatcatccga
    16201 gtaacagttg ctgtcgcttt tttttcttca tgcaacttct ccagaaaacg gatgactaaa
    16261 aagcgatcga catcctgcca tgaagcaatt ttctgctcct gtagaaaatg caagtactgt
    16321 tccaaatcac gttcatagct ttgtcgtgta ttggcggaca atccccgttc aatattcaag
    16381 tagtggagat aatcgttgat ttgctctttc ataataatcc ccctcatgcc tctctatcat
    16441 atcagatacc gcttcattct gatagtcttt ttccataatc tgagcaaaga aaaagccgtc
    16501 tagacactca gacggactgg tttcttt
//
LOCUS       DARPZJ010000054        16510 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.057, whole genome shotgun sequence.
ACCESSION   DARPZJ010000054 DARPZJ010000000
VERSION     DARPZJ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.057"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            184..1182
                     /locus_tag="SLE23_002149"
     CDS             184..1182
                     /locus_tag="SLE23_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8469029.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1294..1803
                     /locus_tag="SLE23_002150"
     CDS             1294..1803
                     /locus_tag="SLE23_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEI8469030.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="SLE23_002151"
     CDS             complement(1833..2492)
                     /locus_tag="SLE23_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEI8469031.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="SLE23_002152"
     CDS             complement(2494..3258)
                     /locus_tag="SLE23_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEI8469032.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="SLE23_002153"
     CDS             complement(3266..3943)
                     /locus_tag="SLE23_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEI8469033.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="SLE23_002154"
     CDS             complement(3980..5365)
                     /locus_tag="SLE23_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEI8469034.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="SLE23_002155"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="SLE23_002155"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="SLE23_002156"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="SLE23_002156"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HEI8469035.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="SLE23_002157"
     CDS             6304..7161
                     /locus_tag="SLE23_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8469036.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="SLE23_002158"
     CDS             complement(7242..7577)
                     /locus_tag="SLE23_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469037.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="SLE23_002159"
     CDS             complement(7644..9014)
                     /locus_tag="SLE23_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HEI8469038.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="SLE23_002160"
     CDS             complement(9092..9628)
                     /locus_tag="SLE23_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8469039.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..11418
                     /locus_tag="SLE23_002161"
     CDS             9937..11418
                     /locus_tag="SLE23_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8469040.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11521..12228)
                     /locus_tag="SLE23_002162"
     CDS             complement(11521..12228)
                     /locus_tag="SLE23_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HEI8469041.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12307..12645)
                     /locus_tag="SLE23_002163"
     CDS             complement(12307..12645)
                     /locus_tag="SLE23_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEI8469042.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12756..13718)
                     /locus_tag="SLE23_002164"
     CDS             complement(12756..13718)
                     /locus_tag="SLE23_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEI8469043.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLVSGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13733..15064)
                     /locus_tag="SLE23_002165"
     CDS             complement(13733..15064)
                     /locus_tag="SLE23_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEI8469044.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15072..15752)
                     /locus_tag="SLE23_002166"
     CDS             complement(15072..15752)
                     /locus_tag="SLE23_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HEI8469045.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15971..16450)
                     /locus_tag="SLE23_002167"
     CDS             complement(15971..16450)
                     /locus_tag="SLE23_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEI8469046.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
BASE COUNT         4885 a         3441 c         2736 g         5448 t
ORIGIN      
        1 tttgcatact tcataataat aataacataa tacctaacct ctcgtaaaaa tactagattt
       61 gttttctttt atttttcatc actagataca ttctataact taccgtttcg atttcgaatt
      121 caaacatttt tgagaagcat tctcaattaa attctgctat agtgtgaaaa gggaggaatt
      181 tttatggaaa tctatgacat tacaatcatc ggtgcaggtc ctgtagggat gtttgccgct
      241 ttttacgcag gaatgcgcca agctaaaaca aaaatcattg acagtctacc tcaacttggt
      301 ggtcaattag caactttgta tcccgaaaaa tatatttacg atattcctgg gtatccagca
      361 ataaaagcaa gtgaattaat cgatcaatta gaaaaacaat taactacttt taaccataca
      421 ttccatttaa aagaagaagt tctctcgctt actcgtgaag acgaagttat cgagattact
      481 acaaataaag gcatccatta ttccaaagca gtcattttag ctttaggaaa tggttcattc
      541 cagccaagaa aattgaattt agataatgct gaatcatttg aaaaccacgg attggattat
      601 ttcgtgaatg atttgatgaa gtatgctgga aaaaaagtcg ctattgctgg aggtggtgat
      661 tctgctatcg attggacgtt gatgttagag cctattgcaa gcgaagttta cttgattcat
      721 cgtcgcccgg aatttcgtgc gcacgaacat agtgtatcac gcttgaaatc ttcatctgtc
      781 aacttgctta ctccctatct catcgatgga ttatcaggca ataatgggga actgacagat
      841 atccggttaa aaaaagtgaa aagtgacgag acgattgatt tgatgattga ttctctgatc
      901 gtcaattatg gattctcttc taatttagaa catctttctt cttggggact tgatagtacc
      961 agaaatgcca ttactgtaaa atcagatatg tctacttcta ttccaggcgt ttatgcagct
     1021 ggtgacatct gtacctatga aggaaaagtg aaactgattg ctactgggct cggtgaagca
     1081 cctactgcag tgaacaacgc tttacactat attaatccaa aggaacgaac tcagcctggt
     1141 cacagcacaa gcttatacga taaaaatctt cgtcctagtt gattttttat atctctttgc
     1201 atttcaagtt aaacccgaaa gcagtttctt gcattttttt catgttccgt taacatgaaa
     1261 tagagaaaga aaaaataaag ggggagcaat aatatggtcg tcaaaactga gactttagaa
     1321 gaaaaggcaa gagaactatt gaaggaacgt ggcgtaactg tagaagatat cgcacaactt
     1381 gtcatgtttt tacaaaaaga ctatatttct gatttgactt tggcggattg tactgaaagt
     1441 gtcaacagcg tgctaacaaa gcgtgaagta cataacgcca ttatcactgg aatccaatta
     1501 gatatattag cagaaaagaa aaaattgatg agtccgttgc aacatattat cgaagatgac
     1561 gaaggccttt acggtatcga tgagatccta gccttgtcaa tcgtgaatgt ttacggtacg
     1621 atcggcttta cgaattatgg ttatatcgac aaggtgaaac ctggtatttt aaaagaacta
     1681 aacagccacg atggcgttca tgtccatacc ttcttagatg atatcgtcgg agcgatcgcc
     1741 gctgctgctg ccagtcgatt agcacacaaa gaaccagaaa aaagaagtcg ccttactcaa
     1801 taattcaaca aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgctttag gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 ttttccacaa gcaaaaacct tatttgtcga caagtcggtc aattgatgac ttacttaact
    10861 caacagtttc ctctcaacca tttagaaaat aaaataccaa tttattttta ttttcttgtg
    10921 ttggcagttg tttttttcga actgttgggt gaatccagca gtagtttttc tacactttgc
    10981 tttccagaag ccacgtccaa tcattctagt tcttttatac aggaaaagaa attaagagaa
    11041 aaaatcgata caattttttc aaaaaatggg gaaagaaacc aaatcagtca ataccttagt
    11101 caattgatcc aacacttact acaaacagaa acgaaagagc agttactcat ccatttgcag
    11161 ataaccaaac agtttacagg aaattatcat cttcaaagcc atttgcagca gttatttcgc
    11221 aaagatgctg ttaaaattac cgcatattca gaacatgctg atttgatcat tacagatcag
    11281 catgagaaaa tttcagatga aacggagact ttctatctgg atacaacgca caatacagtg
    11341 ttatttggca agttaataaa agcggttcat gaactgtata tgaaaaaagg ttatgagaac
    11401 aaaacaaaga ggatgtgaca aaattcttgt cacatcctct tattccaaat aaatggtatt
    11461 caatcagcta actctcggta ttagctcaga tcaaagcgct gatttcacaa cttctttatt
    11521 ttaatctctt cggttgccgc cgaacaataa gatcaagcgc aacagctgca ggaatgtcga
    11581 aagcgctgct gcaacataag tcagtgctgc tgcaaataat acgtgtcttg ccatcggtac
    11641 ttcttcttcc gtcagtagtc cgccttcact caaaatttgg attgctcgcc gagacgcgtt
    11701 aaattcgact ggtaatgtca ccaattggaa aagtaatgct aaagaaaaag cgaaaatccc
    11761 gatattgatt aacgtagagt tccagctaag caatacacct accataatca aggggaacga
    11821 aatcatcgaa ccaaagttag ctgctggaac aagtgctgca cgaatcttca atgggacata
    11881 acccgaagca tcttgtaccg catgtccgca ttcatgagct gctacaccta tcgcagcaac
    11941 tgaagtagac tgtgcagttg cttgagacaa actcaacatc ttattacctg aattgtagtt
    12001 atctgtgaga tctccggcaa tttgttgaac accgacatta tttatctgtt gactttgtaa
    12061 tatatattgt gctgcttgtg taccagtcac attgtttttg cttctcactt gatcgtattt
    12121 tcggaaagta ctattgacgt acgctgacgc aattccggaa ataactaatc caagaatgac
    12181 caaaagaaat gtcggatcta aaaaaccata cattccataa ccatacattt tcgtttcact
    12241 ccttttcgtt tactttattt tatcattagt agtaggaaaa gaatgtgaaa agaccttgaa
    12301 tattctttaa ttctttttca caaattccga tttcagtttc atcggtccaa atccttctac
    12361 cttgcaatcg atattatgat cgccttctac taaacggatg ttcttgactt ttgttccttg
    12421 tttaatggca cctgacgcac cttttacttt caagtcttta atcactgtca cgctatcgcc
    12481 ctctaacaga cggtttccat ttgcatctaa taccactaat ccgtcttcta tgacagtttc
    12541 ttgttcttct ttgttccatt cgttcccgca ttctgggcaa atcaacaagc ctcgatcttc
    12601 atatgtgtac tctgagccac attctgggca atttggtaat gtcatcttct ttctccttta
    12661 aaatctttag tgagcactat tgtaacggaa aaagaagatc ttgaaaagat acatttgtga
    12721 tttttactac aaaaggcacg ttttcgaacg aagtatcatt ctgtttttct gctcttatac
    12781 gattggcata tatcttggat ctctttatag atttcctcta cttctgctaa atcttttgca
    12841 ttcgcaccac ttactaatgg atggcctcct ccatgatggc gtttagccaa ttcattgatg
    12901 atcggcccct tagaacgtaa acgtacgcgg taataccctg aaggctgctg aacaaaaatc
    12961 ccccaagcca gcacttcgtc aatcactcca ggaagtgaaa cgatcgaagc tgtctctgaa
    13021 tcatcgattc catatttatc aagaatttct tgcggaagga ttattcttcc tgcaccattt
    13081 tcatccacct ggatattttg ataaagataa ccggaaagtt tagcgacttt catcggcatt
    13141 tgttcaatct ctctgttcaa agcacttgca tcaaatggat aatttctcaa tatcgaagca
    13201 atctctaatg tacgggacgt cgtggaggga tacaaaaagc gccctgtatc tccgacgatt
    13261 cctgcataaa gtaaccgtgc agccttaacg ttcatcttta aagattcagg aaacatcaaa
    13321 gcaaattctg caatcatctc actacagcta cttgcttttg tatttaccca cacaagatct
    13381 ccataagggt catcattggg atgatggtcg attttgatca gtttttctgc caactgatat
    13441 ctttgatcac tgattctggg tgaattagct gtatcagtca cgatgactag cgctccttgg
    13501 tagaagacat cttcaacttc ttgcatttct gctaaaaagc gaagcccttc aatcgtttca
    13561 cctacttgac gtatttcttt ttctgggaaa ctttcccgta atagttcggc taatcctact
    13621 tgtgatccta atgcatcagg atcagggcgc aaatgcctgt ggataatgat tttatcgtat
    13681 ttttttattg tatctactat ttcttgctgt actgtcattt cactcctgct ttctaagaac
    13741 gttccattac ttgacaaaca acgattgctt tggaaacgat ggtgttttca ataaacactt
    13801 cgatatccag tttagcggaa cgtctgccga tttccaatac acgtggacga atgtctaatt
    13861 cgctttccaa ttggatcagc cgcaaataat gtaggttcac ttgttcaatc aagatatttc
    13921 gtttttggtt catcaccatt gttttttgtg cgacatcaga aatgatttcg ctaagtacgc
    13981 caaaagaaat ggttccaacg ccattgacca tttgtggtgc tactacgaat ttgaacttag
    14041 ggttttccaa acgatttcct tcacggtcag tatcaatcgt atggatattt ccagatatct
    14101 gatccgaaat cgtatctgca atctgcggtt gtcgctggac aagctgcatc gctttcatta
    14161 catcttgccg ggtaatcaag ccttccaatg tcaagtcatc ggaaacgacc ggcatgactt
    14221 ctagcccatc ccagatcatt tgatggctaa cagaggcaat actcattgtt ttctttacac
    14281 tgattggttc tttcgtcatc acccgatcga tgatctggtt tggcgatttc cctaaaacat
    14341 cttttgccgt aacaatcccc atcaaacgat gatggcggtt gacgactgga aaacgcgaat
    14401 gctgcgtttc ttctgacaaa cgctgataat cagaaatcgt atctgtctgc tgcaaataat
    14461 gagtcttttc agctggcata tagatatcac tgacaagcat gatatctttt ttgatcaatt
    14521 ggtcgcttaa cgctcggttg atcatggttg cgactgtaaa tgtatcataa gaggtgcgta
    14581 agatcggcat ttcaagatca tcagctagct ttgcaatctc agcagtcgta ttgaatcctc
    14641 ctgtgatcaa tactgcggcg ccatcttcca atgctaattt ttggacttcc gcccggttgc
    14701 cgacgatcat tagtgatcct ggcgtaatat agcgttccat ggcatgttta gtcatcgcgc
    14761 cgatgacgaa tttattcaag accttgtcta atcctgccgc cccgcctaaa acgtcccctt
    14821 caatgatcct gacgacctcg ccaaatgtca aacgttcaat atgttttttt aatttgcgtt
    14881 cgatacggat ggtccctact cgttgaattg ttgaaactag tccgacattt tctgcatctt
    14941 tgattgcacg gtacgctgtt ccttcactga cattcaattc ttttgcgatg cttcttacag
    15001 aaattcgatt gccaacaggt aaactttcaa tatattctaa aatcaaatca tgttttgtcg
    15061 ccattttctg cctacacttc cagcgtttcc gagacgctca ttatttttcc ttcactatct
    15121 tccagtaact ctacaaaaga ttcgggatct tgttcaatga cagggaaagt attgtaatgg
    15181 attggaacta ctttcttggc acgaattgtt tgcgcagcct ttgctgcatc ttctggcccc
    15241 atcgtatagt tatcgccaat cggcaagaaa gcgacatcaa tatcgaattc ttctgcaagc
    15301 aatcctagat cactgaaata agcagtatcc cctgcatgat aaatcgtttt tccttctgct
    15361 tgaataataa ttccgctagg ctcgcccata tactgaacga taccgtctac ttcatagctt
    15421 gaactatgct gtgcatgtac gaattttacc acgccgaatg gaaacgcatg ttttccaccg
    15481 atattcatac cgaatgaatc tactcctctg ctgttcgcat aatcagcaat ctcaacaata
    15541 ctgataattg tggcttgatt ttcttttgca ataggaatca tatctcctat gtggtcacta
    15601 tgaccatgag taatcagcaa ccaatctgtc tttacttctt ctgcagttaa gtctgtcaat
    15661 ggatttcctg taataaacgg gtcaatcatc acgcgttggc cattttccat ttcaattgtt
    15721 aaacaggaat gtccatgata cgtaattttc atattttaca cctcgcgttt tctctgtatc
    15781 ttttttatta aaaacgattt catcacttgc acatcaatga aaaaatatag ctgctaaata
    15841 tattttcatt ggattgatag tacagtatgt acaaagcaat tgtaacagat aatacaggat
    15901 gcaccaagta ccaagcagat ataatctcaa gtttgaggtc tctgctctgc ttagcttctc
    15961 ttctcgtccc ttaactaatt aaatcagcgt aaataggatg gacgatcttt tctaaatcgg
    16021 ctacttttat ccgaaggctt ctcccgattt caccgcttga cacaattact tcttcttttt
    16081 cttttaaaga actgtctgct aaaaaacaat aatcaggatg tgcgagtttt attccaatag
    16141 gggtgtttgc tccgtgggga tatcctgtat gcattaatac aaaatccatt ccaggaaaac
    16201 caactttacg atctttcgtc acttgtctcg tttttttgta atctaagtga tcgttcaaag
    16261 gaatcaatgc gatgatcacc ccagttttgt ttcctttcac tacgagagtt ttacatatca
    16321 aagctggatc aatccctctt ttttgtagtt cttctgtgaa agattcttct accacatgac
    16381 taaaatcaag tggttgatag ctgatctttt gttcttctaa ataacgttcg acttttgttt
    16441 gactcatcat tgattcactc cctttattct atcgtttatt ataaagcgag ggatgctgta
    16501 ttcaaaaatt
//
LOCUS       DARPZJ010000055        15471 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.058, whole genome shotgun sequence.
ACCESSION   DARPZJ010000055 DARPZJ010000000
VERSION     DARPZJ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.058"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..1126)
                     /locus_tag="SLE23_002168"
     CDS             complement(<1..1126)
                     /locus_tag="SLE23_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8469047.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRD"
     gene            complement(1209..1544)
                     /locus_tag="SLE23_002169"
     CDS             complement(1209..1544)
                     /locus_tag="SLE23_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HEI8469048.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(1554..1928)
                     /locus_tag="SLE23_002170"
     CDS             complement(1554..1928)
                     /locus_tag="SLE23_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8469049.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(1941..2255)
                     /locus_tag="SLE23_002171"
     CDS             complement(1941..2255)
                     /locus_tag="SLE23_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8469050.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="SLE23_002172"
     CDS             complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="SLE23_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEI8469051.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(6009..7175)
                     /locus_tag="SLE23_002173"
     CDS             complement(6009..7175)
                     /locus_tag="SLE23_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8469052.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            7200..7526
                     /locus_tag="SLE23_002174"
     CDS             7200..7526
                     /locus_tag="SLE23_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469053.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDAGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            7679..8731
                     /locus_tag="SLE23_002175"
     CDS             7679..8731
                     /locus_tag="SLE23_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8469054.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            8807..9025
                     /locus_tag="SLE23_002176"
     CDS             8807..9025
                     /locus_tag="SLE23_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469055.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            9012..11585
                     /locus_tag="SLE23_002177"
     CDS             9012..11585
                     /locus_tag="SLE23_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469056.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF
                     DSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSC
                     N"
     gene            11576..11773
                     /locus_tag="SLE23_002178"
     CDS             11576..11773
                     /locus_tag="SLE23_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469057.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            11777..12388
                     /gene="mobC"
                     /locus_tag="SLE23_002179"
     CDS             11777..12388
                     /gene="mobC"
                     /locus_tag="SLE23_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEI8469058.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            12373..13764
                     /locus_tag="SLE23_002180"
     CDS             12373..13764
                     /locus_tag="SLE23_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEI8469059.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            13980..14294
                     /locus_tag="SLE23_002181"
     CDS             13980..14294
                     /locus_tag="SLE23_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469060.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            14287..14781
                     /locus_tag="SLE23_002182"
     CDS             14287..14781
                     /locus_tag="SLE23_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469061.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            14849..15163
                     /locus_tag="SLE23_002183"
     CDS             14849..15163
                     /locus_tag="SLE23_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469062.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            15262..>15471
                     /locus_tag="SLE23_002184"
     CDS             15262..>15471
                     /locus_tag="SLE23_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8469063.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         5203 a         2602 c         2783 g         4883 t
ORIGIN      
        1 gatcgcggat tccgtctcct aaatatttcg catccggcct ttggcaagcc aaaatcagaa
       61 agaaaccaga ttgacgaccc aacatcacga tttgtttgag cttattcaaa atcaccgcac
      121 tttctttcgt cgttaacatc tccatataag ccacgtattc atcaaagatt aaaaagttgg
      181 gtggaagtcc aagataggca taattctctc ctgttttgta gttagacatt tctttcattg
      241 ccttgctacg agccatcata cgttcataga aatcttccac acaagcagaa atttcttcct
      301 tttgtgaata aacatgaggc atcaccgtac ctaaatcagc taaatctgca tttttgggat
      361 cgaggataaa caattctgca tctgacttca atagtgcttc gataatggtg aggaggaaat
      421 aggtcttccc tccacccgtg ccaccagcga ttaacatatg gggtaaagaa tcataagccc
      481 atacttgatt tttcatcaat cgcagagtcc cattttctgc cactacttcg tctatcccaa
      541 ttcgattggc gatcatatca tacagtaaag tatactccac ataggagtct ttgagttcct
      601 tttctactaa ctcacaatac agtccgcttt ctaacttctt ttccaatttt aaaagctgat
      661 cttggtattt cccaagtgaa atttgaacgc gaatagacag taatccatct ttcattcgat
      721 aatagatttt ggggaagtaa ctgatagtct ctctggttcg gctactattc aaatctttga
      781 aaaagccttc actttgagtt tgtttcactt cataccaatg gttctctaga atcatccgag
      841 ctagcttttg tcgatgccac aagcttcgcc aatgatcaag aaaaaagtga atataaagca
      901 atatcatagc tcctgaaaaa gcgagacttc caagcagaca tactaaatct tttatagacc
      961 aaacgatttc aatagtagaa agtgatagct tagaaatatc aaattgtcta aactcttgaa
     1021 aataaaagac gctcatccaa ccgatgaaca gagcgagtag ccagccaaga acaaagtgat
     1081 aaaccaagtg ctgatctcct gcgcgtatgc gatgtccttt gtacattttg atggtttcca
     1141 cctccaatcg aaaaagccca ataggatttc attaggcaat ttcaaaaagt tatgctagtc
     1201 atttactgct acgaggaggg gagttgtttc gtttcaacca attgatttaa aaagccttca
     1261 atagcatccg gcatctccac accaatttct tccaaaatgg attctgcctg ccgacataag
     1321 ttttcattta cttcgacaac tataaagaaa gactcttctt ctcctaacca gtctagtaca
     1381 tcagagtctt cttcactgtc gctattttct ccaagtaaac cttgatgtat aatcagaaac
     1441 attttttcat cagaggttaa tgctttaacg agttgttcct cagtcagctc gccttttcca
     1501 tattgatcga gacaatctaa aatatgttca acattaattt ccataatctt cacctatttc
     1561 tttctttcat tttggttcgt aggatttcct tgattcggct gccgcttcaa gactaaatca
     1621 tccgccttaa tgaaccaatt aacggtagtt ccttctcgaa aaacataatt ggcaacggta
     1681 tccacgattg gattgaccaa ctctacctct gcatcataag caaactcgcg taagggtaca
     1741 ttagctggga tactaacttg aatcattcgc ccttgtgcag aggattttaa attataggtt
     1801 cgttctttta cctcattacc aattgttcca tcctcatttt gcttccgtac ttctcggcgt
     1861 aatgcggaaa aacgcaactt cccaaatgtt aaacctgaat ctacgacaat accttctgtt
     1921 aatctcatct tcttttcctc ctatgctttc actaaatcat caacatacaa cacgtaatca
     1981 gtaaacccac gattctcaat ctcatagcct ttggcaacca aatggggatt cacggctttt
     2041 agcggttggt cttgatcaaa atccttttca ccggcttccg cagctactac cacctcaata
     2101 tcatcggccc gttgcttact ggaatacaaa tgataactgc gaccaatcac cgtagtattc
     2161 cgtccatatc cttctgttat aatttctcct tcaccggcat aacttaactt tccaaaggtt
     2221 tcagccatat ctggcacgac aaatttcaat tccatcttct tttcctcttt tcattgttag
     2281 ttttggatac aaaaatagcg cgactacttt tttaggaggc ggtcgcgcac gttggttctt
     2341 aggatttact tgtatcatct catcacctta gttccggcga ttccagaaat aatagcccgc
     2401 cgtcgcaaaa atcaaagtaa aaccaatgaa cagtaaaaca ttggaatttt tctccccggt
     2461 ttgagggaag gtcttcactg tgggactaga ttcttgagag ccacttggaa cagttggtgt
     2521 ttccggttgt ttcggcgtac ttagtatggt tggaacttct tttggtgtta aggtttgaga
     2581 tttttctttc aaatcttcat tgtgttttcc attgatattc ccatctttat cgtaattgat
     2641 ttccgcaaaa gtaaacttgg ttccttctgg atattttccg gtatctactt ttttcgcaag
     2701 cacagttttg gtgaattctt tatcatttac ttcataatca atcttgccag atttccaaat
     2761 ttctttgttt gtaccatccg gtaataaagc atacagaatt gtttcgaaag cttcttttga
     2821 gccatccagt acatcatgag taatcgacac atcatcaaac atatccacca catcaccatg
     2881 agtaaaggtc tgagaaccgt tttctaggtg ggcctttgtt tggatagaaa catggtgttc
     2941 cactgtacaa ctgacagttt gggcttggtt attcaagcta acatccttcg ctactggctt
     3001 atcgcctgct tcaaaagctt ccttattttc atacacatag ttgaataaga caatagtttt
     3061 atttaaaact tgttcggcgg ttaatttatg ctgaattttc caagttcctg ttttctcttt
     3121 gttcgccaac gttgcgcttg tttctgcaat caccactggt ttggcttttt catctttttc
     3181 ttgggcagct tttgtcgcat ccacatcaat ggcttgcgct accacatacc agtcttcttt
     3241 gatttcatgt agattgtaac tcaatttatc aactagctcg gtagaatcca gagaagttaa
     3301 ttctttgttt ccgtctttcc aagtcgcaag agaagttaaa ctatcttctt cctcaggcaa
     3361 atcatagagc attaaacggt tcaaactaac agaaaatgct ttgttcgtca gcttctcgta
     3421 aggaacggtc accgttttaa ttggttgttt ttggtcttgt tcggtaatgg taaagacata
     3481 ctcactcttc acaaagtctt ctttgttttc cttaaaagta gaacggattt ctaatggcgt
     3541 aatcttttga aaaccttctg gggcttctac ttcttcaagt aaataatccc cataaggaag
     3601 attttcaaac ttgccataac catcaaaccc taattgctcg ttataagctg tggtcgcttc
     3661 atcttcggca cctgtgattt cattggtccc ttccaatggc gacactttaa aggtcagatc
     3721 attgaagcca gtttcggtag tgcccgcagc tgatccagca aatttaaaga aatcaaagcc
     3781 aaagcgaatc acttgttctt ttgccgtaac atttcgggta atcacggcat ttttttcgct
     3841 atcatccacc tttttgatgg atacaggata ctttgtttca tcaaggctat atccttcggg
     3901 cgcttttgtt tcttgccaat aatactcgtt gatagctaaa tgtttaacgg caacttggtt
     3961 cttttcgtct aaagtcaaag tgaccgtttc atcagaacct ttcgttccct tcgctaactc
     4021 tggtttaaaa gcctcactcc atttaacagc ttttccatcc ttagcagtaa acaaggtgta
     4081 ttcagcaccc tcaaagactg ccttaccttg tgctttatcc ccagtatctt tgtcttcttt
     4141 cgtcaaagtg gtttcgccag tgacttcttg attttgccct tttacgttac tggtaacaag
     4201 ggctacggtt tgattggcat acttcaattc gacttttaca ggtttgaacg tattcacgaa
     4261 cccatgacta gctttagttt cggtcacata ataggttccc aattccaacg cattagcaat
     4321 ctcttttggt gtttccgcat gaccgttttc atccgtggtc atttcttgaa cgatttcacc
     4381 ggttggactg tctttgcgaa tggcaaacgt attaccagct aaggaataat tgtcattcca
     4441 aagatcactc cctgtttcaa ctccgctttt atccagaatg atttgccctt tttcccgtgc
     4501 gttttttgaa gtcacgtaaa tggtttcgcc tgctttaatg gtggtagtca tgggggtggt
     4561 atcaatcgta taaggcgccg gtactgattt ttcggtaatg gttacttttg taccatgagg
     4621 aatctcatcc aatgtagcaa tgccttcttt gtcagtagtc acgtcttttg caggtaaagt
     4681 ttttccaaag tctaaatgga aaaccgttcc tggtacaaca tcacccgatt ctttatcgac
     4741 ttttttgatc tttaaagaac cctccgtttc cacatcaatt ttgattgtgt aggtattagg
     4801 tttatcaatc gccccggcca ttaaagtctg ttggccagcc tttttatagg cgacaggtgt
     4861 tccggtacca gcagatttct taagcgtcag cacaccactt tcttttgaat tggcatttgg
     4921 ggtgattatc aactgattac cattcacacg ataatcaatg tttgcggcat tttccacaac
     4981 ctcatcgaac tctgacaaat tcagattatt cgtatccgtc acagtagtcg attgccctaa
     5041 tactgtttta gccgtactat tatggaaggt tggtttcttc tgataatcgt caatggcttg
     5101 atttattttt gcctcaatgg ctgcgatatt tacggcacta ccatctgatc gttttattga
     5161 gtgaagggta tacccattaa cttcttgcca gatcatcttc tgtgccacaa tatgagtatc
     5221 tgcatctgta cctacttttt tccataaaac ggaaactaat ttggctttat cggacatatc
     5281 tggtaacggg tttttctcat agccaggagt gaactcattg taaatcggga ctcctggttc
     5341 aatacagaaa atatcttgtt taaagccgtt gtacactgca taatgcggaa cagtgacttc
     5401 tgacattgga cgaccatcac taaaagttcc ttcaacagca tattgatgtg ctaaatctag
     5461 ttctacggtt accgtttgtg gatgggtaat ttcatcagca aaagtaatcg taggagcaat
     5521 tgctccaaca attgcttgaa cagccaaact caaaatagtt aatacacata atttcttttt
     5581 ttgtttttta tacatgaaat gttctccttt caaattaagc acaaaaaaat aagatgctcg
     5641 cttgaacatc tttgtttata aagtcttttt aaaattttta ttgactgaat agaatggatt
     5701 tgagaatgaa tgagcctaaa aatttaatct aaaatacgaa atatactgcc tttaaattag
     5761 aacacatttt agaacacaaa catttcaaat ttaatcaaat ataataaaat atatttacgg
     5821 gaaaaccttt ataaatcaag gtttttcaaa cttattcaat gatacgaaga aaccaggtct
     5881 taagaaagca cgtaaagctt cacagttttc aaaacgttaa tcgttgttat accaacgatt
     5941 tcagacactt tctcattgcg agaaggtgtc tttttttcgt tctggtaatg agaaaggtaa
     6001 tgacaatatt ataaaccagt gtaagcaatg aatttttcta acgcatttcg ttgagctttt
     6061 tcagtaacat gagaataagt gttaagggta gtttcagcat ttttatgacc caatcgatct
     6121 tgtgtttctt tgatacttgc tccaccttct agtagaagag tagcgtgagt gtgccggaat
     6181 ccatgaatag taacgtgctt aaatttatat ttcttctcta aacgtttcaa tatattattt
     6241 gaatagtccg catgcaaagg ttgattaatg tcaccgtctg catttacata ggtaaagata
     6301 agttgatttt ttgtatttgt atttatgcca aactgcaaaa gctctcgagc ttgttctttt
     6361 ttccagattt ttaacatttc aatagtttgt gcatcaattg gtaatattcg ttcggaagat
     6421 atattttttg tatttttttg aatcctgaca gtttttcttc ttgcattctt ctcttcattt
     6481 cgaatagttg catagctctt tctaacatac attagctgtt cttcaaaata aatgtcagac
     6541 caatgaagag cagctagctc tcctttacgt ataccagtag taatcaaaag ctggaagatt
     6601 aaaatatgtt ttaaaggctc ttctttattg agaatatccc aaaaagcttt tagttcttct
     6661 aatgaaaagt aattttcatt ttctttcttt tcccgctttg gtagatttgt atttgccata
     6721 ggatttcggt gtaatagctc tgcaaaaatg gcatactcaa atatttgaga gctgtaagac
     6781 ttaagctgtt tgatattctt gaattttaaa gcccattcat tgactgcatt ctgacagtga
     6841 acaggagtaa tcttagaaat ggacttattc ccgaattttg gtagtatatg caagcggaaa
     6901 aggtcttttg tacgttgata tgtcgtttct tgtacacgat tcctataaga aggcaaccat
     6961 tcttcataca ctgttataaa caagtcatta gaaggcttat gatagccggt atcttcaatc
     7021 tcgacctttt ttcttgcttc gtgtaacttg gcttcttttt cagttttaaa cccttttttt
     7081 acatagtatt cttgctttcc attttcatct ttacgaacat acaagcggac actatatcgt
     7141 gcaccgcttt ttgttgtgta cttttgtatt gacataacta atctctccaa tctgataact
     7201 tggcgagttg gctgattgaa gaaatagaaa atgagaggag aaaaataatg gatgcaggaa
     7261 ttacagtaat gttagataaa caacaaacga atcaattgaa aaattatgtt tttgaaatga
     7321 caaaagaggc tattgatcaa gcaagaattg atgccggatt agaaagacca tttctaaaag
     7381 gaaaagagat ggctaaatat ttgaatgtat catatacaac ttttttgaaa tttaaaagaa
     7441 tgggattgcc agttatttta ttagaaaaaa tggagttgtt ttcaaaagaa gaatgcaaaa
     7501 aatggatatt gagtcatcaa atttaaaaaa cacctcgttt tttaaatttg atgaagtaga
     7561 aaaaattaaa aagagtgttc ccgtcagttt gcagatcggg ggaacactca ataataaagt
     7621 tctgagaaaa ctttatttga atctattata gcaaataaaa tcagaagcag gtgtgacaat
     7681 gaatgaaaaa gaagttgaaa gcttagttga aaagcaaggc tattctaatt ctgatatata
     7741 tgcagaatta tactatcaat atcctatttt tttaaacgta aatgaaaaat ataagaaaat
     7801 gaaactaagt tctaagttag tttatatgtt actaaaagat agaaatagac tttcattgaa
     7861 aaataacttg tatgatgaga atcaaaaaat ttttttgata tttgaaatca aaaatctcgt
     7921 agaaatttcg ggaatgtcaa aaaatacaat cttatcagca ctagatgaac ttcaaaaagt
     7981 taaacttctt gtgaaaagaa aaaatggctt caataaaagt aaaatgcaaa tgttcccaaa
     8041 tttttattat ttgttaaagc ctgttctgtg caaagatgat gtttataaaa ttaataagat
     8101 aacccatcaa gaaaatagac aaaaaaactt gatagttcaa aatttgaact atggaacaaa
     8161 tcaatattct gttgatagtt caaaatttga actatgcgac acatcaatga aaacaagaga
     8221 caaaaacaat tttgctgata gttcaaaaaa tgaactagaa ttatataagt cttataaaga
     8281 tagtaaagat attaaagaat cacataatga tgatcttctt gaatcacttt caactaaaaa
     8341 taataaatta gatgaagaat tgatcgaaac atttattgaa gaaaatcttc ttaaacaaat
     8401 atggggagaa agtattgtga attgcttaaa actggctagc aatagtgatt atcgtcaatt
     8461 cgacaactgg tacaaaaaat tcaaatatgc gattagatct gctgaaaaag aacaaaaaat
     8521 tcaactgaaa attatctatg aaatttgtaa taacaagtat tttgtagatc atgttagaga
     8581 acagctatca atgactttac gtgacttgat acgaagagca aaaacagatc atcgtatcaa
     8641 acaaaaagac gattatatct ttgcttctct aaaaaataaa gcgttagaac taattgaatt
     8701 gcaaatcagc gaaggaatag ataagcaata agaatagaat tgagtcaaat gaaatggagg
     8761 ggtatctcca cttcatttga gaactttgaa tataggaggg gttattttga ttaaaaatcg
     8821 tttaatagat caagtttggt gtctagatca aaatacagat agtctcgaat taatcgagac
     8881 tatttgcttc aacactatag ttctcgattt aagagctgaa aatgataatt gtgtaactca
     8941 tgtcataatt aatcaaaaaa tggctcagaa gctctctgag agcctcagaa aatgggctaa
     9001 gggaggtaac gatgaaaata attgaaaaaa agattgccaa taaaaaaata aattggttgg
     9061 ttgttaattt tcttgttctg atagctatga ttatttttac aagtaatatt gctcatgcga
     9121 gtattttcaa ttggtttgat gacacaaaaa gtcaaacaga gtttttgaat aattctcttt
     9181 atagacctta cctaaaaaag tacaatggag atttccttag tcagttcggg atttggctcg
     9241 gatgggctgt ggtaaaaggc atgtttactg tgacagattc gattcaaaat atgattccag
     9301 atgtgctgga tttgttcaat ttcattgaaa gtacagggct aaataatgtt tatcaatcag
     9361 ccgtaaatac aattgtcatt ggattaatga tcctttcatt gatgtttgtt ggttacaaaa
     9421 tgattactgg aaaaggaaca gtggatttaa aatcggttgg aatgaacgta gtgatgtcta
     9481 tagcattaat acttttaatg ccaaccatga tttctagtgg tattcaattt gctaaaacat
     9541 tttataagga ctctactacg attacaaatt cagatgacgg agtcgcttgg tcattgataa
     9601 aacaaggagt aacagattta gcatatatta ataaaacaga tcagtactca agcattgata
     9661 aaacggagga tcgaaataat ttaacacgaa aaaattttca acagacggat ctcacacaag
     9721 tgttaacgga taaagtgatt gataaattgg aaaaagaaaa tccaattgcg gacaatcttc
     9781 gttatgaatt agttgaaaat tctaataatg aatttgttgc tacaaagttt tctgacaact
     9841 tcttatcaac attttctgat agcttgaaat caggctatta ccgataccaa gcaaatctat
     9901 gggggatttc aattgggttg acagcgttag caatcgccta tgtgttcagc gcgtttgtga
     9961 tcattacagc aatactagaa cttgcattta aacgtgtgtt aggtgttctt gtttttgcaa
    10021 cagatattga gacaggacag cgttcaaaag ttgttctatc agatattcta caatgttact
    10081 taactgttgg gtttcaagga tttgggttat caatgtttgc tatgtttatc aattttctga
    10141 actcaggaca aggtatctca acaaatattt ttataaaaac aattgcttat atctgtgccg
    10201 tttttgtttt aatcaaaggc agtggaacag tcatgagata ctttggtgtt gatattggac
    10261 tcaaagaagg ctatgggcaa cttgcttctg cttttggaat gggcgcaatg ctgtttagaa
    10321 aaggatcaaa tggatttaat cgtgctaaag gaagcggaga aggagaagat cgaaaaccag
    10381 aaaagaattt cggcgaaact ctatcaaaaa aagctggcaa aactggaaga gctttgggat
    10441 atgcccatga acgtggatta tccggtttag cttcagatgg agctacaatg gctagtgaaa
    10501 gagcaacaaa accatttaag agtatgcgtg atatagctaa tgataccaag aataagttta
    10561 aagaaggttt agatgatggt acagtgtccg ctattaataa aaatagcaaa cctatgttag
    10621 ctaaaaataa agaagatgaa actggaaaat atgctgattc cgtgccaaca cgtctttcag
    10681 atagaaaaga tggtgctaaa gttgaaaatg ccgatagaat tatgtctagt tctgaacgta
    10741 tgcgtgaagc aatgaaaaat aatgctgaat cgaataataa tcctgcaagc gcaattcagc
    10801 aaaaagtcca acaagatatt gaagaacgta aaaatgctat gcacggtcaa gctaagtctg
    10861 ctgaagaatt aattaatcag aagcgtcatg aagcgaaata cacgcctgaa gcaatgaatc
    10921 gcgaggaaat aatgttaagg aaacgtgtag aagggcggac aggcgctaat attgacggaa
    10981 aagaagcgtt gaccaaagaa agaattcaag aagctaaaaa ttcaaataca ggattagaaa
    11041 aattagtcaa agaaaatcca caaaattcta caagtagtca tggtggccga tcagtagatg
    11101 tccgagaaaa tattcaaggt tcactgaatg gtcatgttgg acggaatgtt gatgtaagag
    11161 agaatttaca aagttcttca aatgctcaag gtactaagac aattgatgtt cgagaaaatc
    11221 tgcaaagtag cagtacaagt caaccaaaaa cagtagatgt tcgagaaaat gtacaaaatt
    11281 ctacaagtag tcaaggattc aaaacagtag atgttcggga gaacattcaa aaagatagtg
    11341 gagaaatgaa agaaaaaaca caaaaaatca atatcgttga agacagaaag tcagcgaaaa
    11401 aatttgattc aaatcatgaa acagtgatta ttgatagtga aatccgtgaa aatgataagg
    11461 gatcaaaatc aagacgaaga ttcacttatg aagacaatga gttattcaga gatacactta
    11521 atgatcctaa tccacttttc gataatttat taagaaataa aaggggggga ttgtcatgca
    11581 attaattcta aagattagta cgcatgattt cttagaactt gacgaattat gtgaatcagt
    11641 aaagaacgca acaaatgaaa aaatcacggt cactaattat attgaactga tgattcaaga
    11701 agaattaaag atgaaaaatg aaatagagag caatttcaaa tgttgctctc tagaaaaaaa
    11761 tgtgagggga taatcaatgg atgataaaca aaaaatgtac gaaaaaaatc gcaaacatag
    11821 tgaggcctta aattttcgtg tcgataaaaa gacttatctt gaactgacat tgattgcaaa
    11881 acaaagggga atttctagag cagacgtttg ccgtgagcgg ttaaagggac tcaaatatga
    11941 accgccgttg ttagctgaag atgatagggt agttttaacc aaacagttaa atcaaattgg
    12001 taacaatttg aatcaagcgg taaaggcatt aaatatcatt gctaaatatt ttagagaaga
    12061 atctgaagat aaaaaagaaa agagcctaca ttttagtttt gatgctagcc gttacaacat
    12121 ttttaaagat gaacttgcga atagcatagc aaaaaagttg atgattagtt atccagatga
    12181 catttttttg gagtccaatc ggagtgcccc ctcttttttt aaattatcag aagtagaaaa
    12241 agaatatttc gaatattgga tagaaaagca aactagaccg ggtacgaaag aagagtattc
    12301 ccaaaaagtt gatcggaatt taattcactc aattcagatt attgcaagtt taaaagatga
    12361 ggtgaaacaa ctttgggagc tactataaca tcgaaaggac gcaagaaaaa tttatcctcg
    12421 ctattacaat atgcagctaa tccttcaaaa aaagaaaaat gtgttgcagt ctcaggaata
    12481 aattgtagtg atgatagtga ggaagcactg caagaaatga atttagtacg taccaagatg
    12541 aataaatcta aagatatagc acaagcgttt catgttattc attcgtttga taagagtact
    12601 tctaaagagt taagtattga taaaatgcac gaaatagctg tcgaatttgc agagaaagct
    12661 tttccaaatt cgcaaatcat tgttgcaagt cacaatgata aagatcattt tcatagtcat
    12721 cttgtcatta ataatattaa catggaaaca tgtaaaaggt tgcgtattga ccctaaagat
    12781 ttagaactaa tgcgaaaaat taacgatcaa gtcctcaatg aacatggtct tgaatcagtg
    12841 aataatgagt actatgaaaa cttagaaaag agaaccaatc tttattcaaa cgatccttct
    12901 aagatgaaat atggaaaaat taattatcaa gagtttgtgc aaaatgcgat cgaagcaacg
    12961 ttggaaaaat gcgaagtgaa ttcttttgaa gatttttcgg atcatttggc aaaagaatat
    13021 aacattgaag tttatcaatt ttcaaaaaca aataacaaac ttggctatgt tctttacaaa
    13081 caaggtgtaa atttctatga gcgtagaggt gagttaatta ctttaggaag agataaacaa
    13141 tctagaaaag aaaaaagtca gtatgtcgaa cgtactttta gtgcaagaaa gttagggaaa
    13201 agatattcat ttgaatctgt ttctgaacaa cttgaaaaga atttagaaga atcacatata
    13261 aaaaattttt ttaatatgga aagagagcaa gttatgtcgc taattagtgg agtaaattac
    13321 aaaactggtg agttaaatgt accgtttgtg gaattagatt ccatcgcaca aaagcaattt
    13381 agcgaccgtg aaggcgatga aaaattcatt aaatatgatg acttcttgcg agaggtagac
    13441 aagcattttg taaatacaat gtctttagaa gatgatcaag aatacacgat taaacttcat
    13501 acggatgtga atcctcaaac tttacgtagt gcgaaaagta aaacaatttc tattaaaaag
    13561 actgatcaga aagagttatt tctaccggca aagggttttg aaaattgttc tcatacacct
    13621 tctgctaaac agattcacta tcaaatcagt cgcataatga atgacgatgt aaaaatgtat
    13681 cgtgctaaaa aggattatga attcacacaa caaatgattg aaaatcagca aaaaaggcaa
    13741 caaaattttg aaatggaatt ctgaatgggc ttgttagtgg actttccagt tttttgccta
    13801 tgaagagttg cttggaaaga agcagttttt aggacatacg ccagctaccc atctacttgc
    13861 cagtcaatcc gccccgctca cgctaggcta ctttctggca agtcagatgg cgggtaaatc
    13921 tctgagggag caagctccct acagactccc tcccaaaaaa agaaaggtgg aagaaaaaaa
    13981 tgaactatcc atattttaaa gtctcggctt cagaagaaac taaagaaata ttcaacaatt
    14041 tttacaacca aaacaaagga atttttggtt caaaggcaaa tatgtttcgt gttatggttt
    14101 caaatttacc agtgttagct agtccatcaa ataataaatt taatgatcct gaaagcatta
    14161 aatttgaaca aaaaatttca gaactagaat caatgataag taatgaagta attgaaaagc
    14221 tggatgacat tgatcaaaag ttatcgtatt ctctaaaaaa caaatacaaa acggaggaga
    14281 aaaaagatgt ttaaagttta cttcccgttt cagtggctcg ttaaaggaat tcttttagtg
    14341 ctactaggat tgattctttt tggaagttat ctaacaatta aagccagaca ttttccagaa
    14401 gaaaagccaa taaaaattgt aacaaaagat ttaaaaatag gtgaaactta tcaggcagat
    14461 ggggttgaac taacatttaa aaatattgaa gtgaccgaaa aaagaaatga atttgcacaa
    14521 catgatcgtg tattacaagt gacctataca cttataaatg atacagaaaa tccgatacgt
    14581 ccacaacaat ggtcgattga aaataaggat ggtgaagaac tttatgagta tgatatgata
    14641 ttggataatc cagagtatat tgaaagtggc aaagaagaaa cagtaaatta ctattatgaa
    14701 ttaccgattg aaaggcagga ctaccaaatc gtagtacgta gagagaatgg ttacatagtt
    14761 gggttgccat ttactttata agttttattt tgttagtagt ttttaaggta atatcagttt
    14821 tgtgattttt gaaaatggaa ctgggagaat ggctgaggaa aataaagttg ttccgtttga
    14881 aacattagtg ataaataagg aagagtttga gcaacttttt cttgattttt ttattcaata
    14941 tgacatgatt tatgatttta gttcgtcact agatttattt gaattagaag cagaaataat
    15001 agaaaacagt cgagagaaga atggtaaaat cattatttca gtagaaaaat tcaatgaatt
    15061 attctcacaa acatttgaaa tagatccaga ctattatcaa ccacaagaag tttttcgaga
    15121 gtttagaaat aagattattg gttttagtca aactacaaaa tgaaagctta ataaagcaag
    15181 tgttgataga attattcctc aacgcttgct ttattttatg ggcacttcat aatagaggta
    15241 tagagaagag aggtattcat tttggatact attactccaa caaacttcaa agaaaatata
    15301 ggtaaagtgt tgcaagaagt agttcattca aattctgaaa tagaaattac tagggattct
    15361 aaaaatggat tgaacgatgg cgtcattatg atttctaaga gaaaatggga gttgttacaa
    15421 gaagaacttt atttacaacg aacgggtaca tgggcttatg tatctgattt a
//
LOCUS       DARPZJ010000056        15310 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.059, whole genome shotgun sequence.
ACCESSION   DARPZJ010000056 DARPZJ010000000
VERSION     DARPZJ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.059"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(260..1492)
                     /locus_tag="SLE23_002185"
     CDS             complement(260..1492)
                     /locus_tag="SLE23_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEI8469064.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1747..2316
                     /locus_tag="SLE23_002186"
     CDS             1747..2316
                     /locus_tag="SLE23_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEI8469065.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2494..2934)
                     /locus_tag="SLE23_002187"
     CDS             complement(2494..2934)
                     /locus_tag="SLE23_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEI8469066.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3092..3856
                     /gene="map"
                     /locus_tag="SLE23_002188"
     CDS             3092..3856
                     /gene="map"
                     /locus_tag="SLE23_002188"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HEI8469067.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3888..4811
                     /locus_tag="SLE23_002189"
     CDS             3888..4811
                     /locus_tag="SLE23_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEI8469068.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4887..6026
                     /locus_tag="SLE23_002190"
     CDS             4887..6026
                     /locus_tag="SLE23_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEI8469069.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6019..6819
                     /locus_tag="SLE23_002191"
     CDS             6019..6819
                     /locus_tag="SLE23_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8469070.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6819..7646
                     /locus_tag="SLE23_002192"
     CDS             6819..7646
                     /locus_tag="SLE23_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8469071.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7624..8358
                     /locus_tag="SLE23_002193"
     CDS             7624..8358
                     /locus_tag="SLE23_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8469072.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8458..9324
                     /gene="rfbA"
                     /locus_tag="SLE23_002194"
     CDS             8458..9324
                     /gene="rfbA"
                     /locus_tag="SLE23_002194"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEI8469073.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9338..9910
                     /gene="rfbC"
                     /locus_tag="SLE23_002195"
     CDS             9338..9910
                     /gene="rfbC"
                     /locus_tag="SLE23_002195"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEI8469074.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9932..10960
                     /gene="rfbB"
                     /locus_tag="SLE23_002196"
     CDS             9932..10960
                     /gene="rfbB"
                     /locus_tag="SLE23_002196"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEI8469075.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11058..11909
                     /gene="rfbD"
                     /locus_tag="SLE23_002197"
     CDS             11058..11909
                     /gene="rfbD"
                     /locus_tag="SLE23_002197"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEI8469076.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11943..13976
                     /locus_tag="SLE23_002198"
     CDS             11943..13976
                     /locus_tag="SLE23_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469077.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14020..15299
                     /locus_tag="SLE23_002199"
                     /pseudo
     CDS             14020..15299
                     /locus_tag="SLE23_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
BASE COUNT         4659 a         2655 c         3205 g         4791 t
ORIGIN      
        1 cgagtctctt ctttctgagg agagacatca agagtcgctg cgctactgct cctgacctct
       61 ctcctcagaa agaaaggcat ggcagttagg ttcacaacgc aaaacattgt gcttttgatg
      121 aggttgaact tttacacaag attgtggact tgactaaaaa aacggtgggg ttgtttagcg
      181 aaataaagga tctaagccaa tagcttagat cctttattct atgctttata ttattttttg
      241 catgtgtgcg aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc
      301 catcttcacg gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg
      361 tttgacttct attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt
      421 tcacactgaa ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata
      481 atgtattgaa aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga
      541 cttctcctaa acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc
      601 cttgttcggc agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga
      661 tgatggtgcc agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac
      721 tgtcaggtgc tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag
      781 cattatagct tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg
      841 taccgggagc agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt
      901 ttgctaattt ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag
      961 tcgttttgaa aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga
     1021 agacttttgc tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg
     1081 cttgagttgc cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta
     1141 ctcgatggct atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc
     1201 ttgctccttt ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa
     1261 tacgatccgt tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa
     1321 cgataacctc agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg
     1381 cctgttccac gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt
     1441 ctgcaattaa gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa
     1501 ttcctcctca ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa
     1561 caatgaggct ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat
     1621 gttactactt gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa
     1681 aaacatgtta caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta
     1741 aaaaatatgg caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa
     1801 gtagctgcca ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat
     1861 tgttccacgc aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt
     1921 tttgagcaga tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat
     1981 acgattatcg atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat
     2041 cgttcactgt acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact
     2101 tactttgtga atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc
     2161 gaatctttgt ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca
     2221 agcatcatcc atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct
     2281 atcttgaaat tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc
     2341 agtaggtaac aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca
     2401 tttttaactc ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga
     2461 ataaatctgg atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc
     2521 gaaagcttct aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc
     2581 ggctcctttt gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca
     2641 gaattcatcg taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc
     2701 caattcttgc aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta
     2761 tgtataagta gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt
     2821 acattcgttg atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc
     2881 gatttcttca gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg
     2941 cctcctcgtt tataattatt taacaattat gaattatacc aaaacatcat tgaaaagaaa
     3001 ataaaaccta gagacacctg gggaatgtca tttggctaaa tgtatgccgc tatgttaaaa
     3061 tgagagggat ttgtaaaaag gagacgaaaa tatgattact ttaaaatcag cacgtgaaat
     3121 tgaaatgatg gcagaatctg gagctttatt agcagatgta cataaaaatc tgcgtgattt
     3181 tataaaacca ggaatcacaa gttgggatat tgaggtattt gtcagaaact atatcgagag
     3241 tcatggcgga attgctgcgc aaattggctt tgaagggtat gaatatgcga cttgtatcag
     3301 tataaatgat gaaatttgtc atggattccc tcgtaaaaag cctttgaaaa acggtgattt
     3361 ggtaaaagtc gatatgtgta tcgatttgaa aggcggcatt tctgattctt gttgggccta
     3421 tgtagttgga gaatctacac ctgagatcga ccgattgatg gaagtaacga agaaagcttt
     3481 gtacatcggt attgagcaag cacaagtagg gaatcggatt ggtgacatcg gtcatgctat
     3541 ccaaacttat gtagaaggcg aaaatctagc gatcgttcgt gattttattg gtcatggcgt
     3601 tggtcctacg attcatgaag aaccagcagt tcctcattac ggagaagctg gaaaagggtt
     3661 gcggttgaaa gaaggcatgg ttatcacgat cgaacctatg gttaataccg gaacttggaa
     3721 aatgaaaatg gatcctaacg gctggactgc gtatacaaga gacggcggac tttcttgcca
     3781 atatgaacat acattggcta ttactaaaga tggtccaaga attttgacat cacaaggaga
     3841 agaaggcact tattgatcta tccagtcaat aggtacggga gaggtacatg aaagtttgga
     3901 acaaaataaa acaaaatgaa aatctgatgc gctttattga gacgactcaa aagcgcatca
     3961 ctgattcaga aatgagtacg acctctgtcg tcgttgctta ttatttactc ttgtctttat
     4021 ttccattgat tattgctttt ggtaatattt taccgtttct ccacatcgat caagagactg
     4081 tactgaccta tttacgagaa gtgattcctg agaccgttta ccagtttatc ggtcctgcaa
     4141 tcaaagacct tttgacacaa agttcaggag gcttgttatc cgtttctgca ttagcggctt
     4201 tatggtctgc aagtcaaagt atcaatgctt tgcaaattgc gatgaataaa gcgtatggcg
     4261 tagaaaatag aaaaaatttt ttgatcgtcc gtttcttctc actaattgtc attgtcttgt
     4321 tcatgattgc tattagtggg gtaactatcg ttcttgggtt gggacagctg attttggatg
     4381 ctattcagcc aatcgtacaa atacccgtga actttatcga tcagttccaa actttgaagt
     4441 ggccaatcac attggtagct ttatttgtca tcatgttctt gatttattta attgtcccta
     4501 atgctcagtt gaagttgaag acgatcattc cgggcacgat cttcgctact gtcggctgga
     4561 tgctgttatc acaagtgttt agtatctatg ctaggtattt tgcaacgagg atcagcggtt
     4621 atcagatcat aggaagtttt attgtactca tgctttggct taattttgct gctacgatca
     4681 tcattttggg cggaatcatc aatgcagttg ttcaagaata cgtgacgggt catcaaatca
     4741 aaaaacgtcg agatccaagc cgaaaatggt tcaataaatt gaaaactaaa ttttctcata
     4801 aaaaaaagta gaaacaagag ttcttattgt aaatttatat cagtaattta taataattat
     4861 gactcttaat taaagtaggt gcccatatgc ttgtttcttt tagtatggtt ataagatttt
     4921 ttctgacaat tttattatca ctgatattaa cacctgtatt caaaatcatt tcagtacaaa
     4981 caggtatggt cgacaaacca aatgaaagaa gaataaataa agttccaatg ccttcagcgg
     5041 gcggactgcc tatctttatt tcatttgtta tatcgacttt attcttattc cgtaaaatta
     5101 tccctcaatc gtatattgta ccgatcttga ttgcttcttt agtaatcata gtcacaggag
     5161 tgctcgatga taaatatgag ctgacaccta aacaaaaaag tatagggatc ttgattgctt
     5221 ctcttattat ttattttgta gcagatatac gtattgattc cttcacgctt ccttttattg
     5281 gatatatcca actaggctgg cttagttttc ccgtaacgat tttttggatc ttcggtatca
     5341 cgaatgcggt caatctgatt gacggtttgg atgggctggc ggcagggatt tcattgatcg
     5401 gtttaattac gataggaatc attggatatt ttttcctcca tgcttctaca gtgtatattc
     5461 cagttgttat tttctgtctt gtagcaagta ttatcggttt ttttccttac aatttttatc
     5521 cggcaaagat ttatttaggc gatacaggag ctctattcct agggtttatg atggccgtcc
     5581 tttcactaca agggctgaag aacgtgactt ttgtttcatc gatttctttg ctgatcgtca
     5641 tgggagtgcc ggtaacagac acgttttttg ctatcattag gagaaaagca aaccgtgttt
     5701 ctttttctac agcagataaa aaacatcttc atcaccgact aatcagttta ggctttactc
     5761 ataaaggtgc tgtcctgacg atttatgcga tggctttgat gttttctttc acagctatgg
     5821 tcatgaatta tactggaaga atcggaacga tcatattgat tattgccatg ttgtttgctg
     5881 caattttatt atttgaattg attggtctga tcaatgagaa acatcagttt attttaaaaa
     5941 cattgcgatt tttagggaat aaagagtacc gtacgcaagt aaaacagaaa tatttgaaga
     6001 aatggaaccg tcatatagat gaataacaaa ttaaaccagc cgatccttat tagtattgtg
     6061 acggcaaaca gtgataaaat ttttcggaca ctagataatt ttatttcaac tgtaaaagat
     6121 gaaacagcag taaaaatccg aatttttgac aacaattcac ttcccgagta caaaaaaaga
     6181 ctaacagagt ataggaaata tccctacatc gatatctatt ttcatgatga aaattccgga
     6241 tttggttatg gacataatca caatctgata gctagcgatt ctcgctatgg cattatttgt
     6301 aacccagata ttttagtgga tgaagagaca gttacagcat tggtcttgtt attgaaagaa
     6361 catccggaat gtgcgatgtt agcacctaag attcttaatg aagatggaac aactcagcac
     6421 ctcatccgtg agcagctggc tgtttttgat tacgttttgc gctttgtgcc tttcaaatgg
     6481 gtcaaaaaaa agtttgacaa acgactggct gtgtttgaat gccgaggatt gcctactgat
     6541 gctaatagtt atgtacggat gatctcaggt agttttatgg tagctgatat tgataaattt
     6601 aaagagataa aggggtttga tgagcgtttc ttcatgtact ttgaagacaa cgacttgtgt
     6661 ttgagttttg aaaaagcagg ttacaagtta ttgtacacac ccttttatgc agttatccat
     6721 ttttacggga agggtgcgca tcgaaatgca aaactgtttc gcgtgttttt gacttctatg
     6781 atgaaatttt tcaataagtg ggggtggcgt tttttctgat gaaaccagaa atattagtag
     6841 tcgttgtgct ttatcagcaa ctattcagtc aatctccagc ttatggacca ttaagcaaag
     6901 cacttagcga aaagcaaatt cagcttatta tttacgataa tagtcctcaa aggcagcaaa
     6961 atgagctgtt tgaaaaagaa aatatcgttt atcatcatga tccgcaaaat cctggtttag
     7021 cggtggctta taattttgcg ttgtctcaag cagatgaagg aacacgttgt ctcgtcactc
     7081 tggatcagga tacgaggcta gtcgacgatt attttgaact attgcgtaaa gtaaccttta
     7141 cagatgaatg tgttgctgca gttccgatga ttttttctgg gagccgacaa gtttctcccc
     7201 tatattcaga tcgttatatc aatcgtacag ctcaagcagt agaagttgaa ggcccaacag
     7261 ctgaacgaat catggcaatc aattcaggtg ttgcctggtc tgtcaaattt ctaaaaaaga
     7321 ttggcgggtt taatcctgct ttttctttag attttttgga tcattggctg ttttggaaag
     7381 tggatcagtt ggaaaaaact gtggagatcc ttcctgtacg aatggaacat gatctttcgg
     7441 ttttagacta tgaaaaagtt tcaagtaatc gataccgttc tattttacaa gcagaaaatc
     7501 gattttatca tgaatatgat caaaggcatt tatccagtca ccgacgacaa ttattgttaa
     7561 gaacagctaa acagttcttg accgtcaaaa accggcatat ctggcggatg actttgcgct
     7621 catatgttaa gaattggaag gtgtgaattc gtgcgttcgg tttgtatagc tacctttaat
     7681 ggaggcagat atttaagaga gcagttagat agtattttat ctcagctttc agcagaagat
     7741 gaagtagtca tttctgatga tgggtcagta gatgatacat gggatatatt aactgaatac
     7801 gcagaaaaag ataagcgaat ccagcttttt tcggggcctc gtcaaggatt gatcgctaat
     7861 tttggttatg cgatccagca gacgaaagga gatctaatct ttttggcaga ccaagatgat
     7921 gtttggttgg agacaaaagt gaaaaagatc actgactatt ttgagcagaa tccggatcag
     7981 ctagtagtag tttctgattt aatcattgtg gacagcgagc tgcaagagat ccatgattcg
     8041 tatttttcgt ttcgaaattc caaagaagga tggcttaata atgtgataag aagtcactat
     8101 attggtgctg gtatggcttt ccggtcttct ttaaaacccg atattttgcc gatcccgtca
     8161 gaagtgccga tgcatgatat gtggattggt ttgctgggag gaaagaagac tgggttccta
     8221 agagaaccgt taactctgta ccgaagacat gatttaaacg cgagtgagat tgaaacacat
     8281 tctaaattac ggcaaaaaat ttcttggcgt gttcatctga ttacggcgtt gatcaaacga
     8341 aaatggttta aacgttgata aaagatgttt aaatccttaa tatttccatg acaaatataa
     8401 caattgatga gataataaca aagtgaaatt tgaaatcaaa aaggagagca gatatccatg
     8461 aagggaatca ttcttgctgg gggcagcgga acacgtctgt accctttaac aaaggcaaca
     8521 tcgaaacaat tgatgccgat ttatgacaaa ccaatgattt attatccaat gtctactctg
     8581 atgttggcgg gaatcaaaga aattctgatt atttcaacgc cacaagatac accacgtttc
     8641 aaggaattat ttggaaacgg aaatgattta ggactgcaga tcgaatatgc agtacaagaa
     8701 agtccagatg gattggcaca agcgtttatc attggagaag aatttattgg agatgatagt
     8761 gtctgcttgg tattagggga caatatttac tatggtggcg gtctgtctaa aatgttgcaa
     8821 cgagcagctt caaaagatac aggcgcgaca gtatttggct atcatgtcaa tgatccagaa
     8881 cgctttggtg tagtagaatt tgatgagaat atgcaagctt tgtcgattga agaaaagcct
     8941 gctcagccaa aatcaaatta cgctgtaact ggcctttatt tttatgacaa tgaggtaatt
     9001 tctatcgcta aaggtatcaa accttcagaa cgtggagaac tagagattac ggatgtcaat
     9061 aaagcatatt tggataaagg aaaactatcc gtagaactta tgggacgcgg atttgcttgg
     9121 cttgatacag gaacacatga atcattgctt gaagcatcta cctttatcga aacaattgaa
     9181 aaacgtcaga acttaaaagt ggcttgtttg gaagaaattg cttaccgtat gggctacatc
     9241 gataaggaac aattgctggc ccttgcacag ccattgaaaa aaaatcaata cggtcaatat
     9301 ttattgaatt tggccgctga ataaggagtc cttacagatg aaagtaacag atacaaaatt
     9361 aacagatgtc aaaatcgtag aaatggacgt ctttggcgat catcgcggtt tcttcacaga
     9421 aagttattca aaagcaaaat ttgcagaaca tggattgaaa tatgactttg ttcaagacaa
     9481 ccattcacta tcagctgaag ctggtgtcct tcgggggctt catttccaaa aaggagaagc
     9541 tgcacagaca aaattgattc gggtagtcac tggagcagtt ttagatgtag tagtggatat
     9601 ccgcaaaggt agcccgactt atggtcaatg ggacggattt atcttatctg aacataatca
     9661 tcgacagttg cttgtaccta aaggatatgc ccatggattc gttactttga caccaaatgt
     9721 gaacttcctt tataagtgtg ataattacta taatgcagaa gcagatgggg gcatcgcatt
     9781 tgatgatcca gatttagcga ttgattggcc aattgatcca tcaagagcga ttatgtcgga
     9841 aaaagatcac cgtcatccga cattaaaaga atttgaagca gaaaatccat ttgtttacgg
     9901 agaaatctaa gaattaagga gaaattttct tatgaaaaac atcattgtta ccggaggtgc
     9961 cggattcatc ggctctaatt tcgttcatta cgtggtaaac aatcatccag aagtgcatgt
    10021 cactgttttg gataaactga cttatgcagg aaacaaagag aacttggctg gacttcctag
    10081 cgatcgcgta gaattggtcg taggagatgt tgcagatgca gaattagtgg accgtctagt
    10141 aaaagaagcg gacgcagttg ttcattacgc ggcagaatcc cataacgata attcattaaa
    10201 agatcctttc ccatttgtac aaacgaatat cattggtacg tatacacttt tagaagcttg
    10261 ccgcaagtat gatgtacgct atcatcacgt atctactgac gaggtttacg gcgatcttcc
    10321 attacgtgaa gacctgccag gacatgggga aggcgaagga gaaaaattca ctgcggaaac
    10381 accatataat ccttcaagtc catattcttc tacaaaagct ggttcagatc tgttagtaaa
    10441 agcatgggtg cgttcttttg gcttacgtgc aaccatttca aactgttcaa acaactatgg
    10501 tccttatcag catattgaaa aatttattcc tcgccaagta acgaatatct taagcggtat
    10561 tcgtccaaaa ttatatggcg aaggaaagaa tgttcgtgac tggatccata cgaatgatca
    10621 ttcttcagca gtgtggctga ttttgacgaa aggcagaatt ggcgaaacct atctgatcgg
    10681 tgcagacggt gaagaagata ataagaccgt gatggaattg atcttagaaa tgatgggtca
    10741 accaaaagat gcgtacgacc atgtaaacga ccgtgcagga cacgacttgc gttatgcaat
    10801 cgattcgaca aaattacggg aagagttagg atggaagcct gagtttacga acttccgtga
    10861 tgggttggct gacacgatca aatggtacga agaacatgaa gactggtgga aaaaagaaaa
    10921 agaggccgtt gaagcagcat atgccaaaaa tggacaataa tacagagaaa atgtcactgt
    10981 attaatggaa aaacacatgt gaggcaggcg ctcgcctgtc tcttttttaa aataaaaatc
    11041 aaggagcgga taatcatatg tttttattaa ctggaggaaa tgggcaacta ggtacagaat
    11101 tgcgccattt attagatgaa aaaaatctgc aatatgtttc aacagatgca aaagacttgg
    11161 atatcacaga tgccgagaaa acaatggctt acatcacaga attaaaacct gatgttattt
    11221 tccattgtgc agcttacaca gcagtagata aagcagaaga agaagcaaaa gaattagatg
    11281 agaagatcaa tgttgatggt acaagaaatg tagcacttgc agcaaaagct gtgaatgctc
    11341 aattcgtcta tatcagtaca gactatgttt tcgatggaaa aaacaaaaat gtagaatacg
    11401 aagtagacga ccaaacgaat ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa
    11461 aagcagtaga agagatttta gaagactatt atatcatacg aacttcttgg gttttcggga
    11521 tctatggaca caatttcgtc ttcacgatgc aacgcctagc ggaaacccgc gacaaactga
    11581 ctgtagtaaa tgaccagttt gggcgaccaa cttggacacg tactttggca gaatttatgg
    11641 tatatgtcat cgaagaaaaa gcaccatttg gtatttatca tttgtcgaac gaaaatagct
    11701 gttcttggta tgaattcgca aaagaaatat tgaaagatac agatgtagaa gttgcacctg
    11761 ttacgtcaga agaatttccg caaaaagcaa cacgtccgca gtattcagtc atgagcctga
    11821 aaaagacaga agagttagga tttgtcatac caacttggca agaagcactt gcgcaaatgc
    11881 tggaagctgc caaaaaaatg aataagtaat ttccttttat caaatagaat ttggagcatg
    11941 atatggaaaa acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aaccaggcag
    12001 attcgaattt ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca
    12061 tcgtggtcat cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg
    12121 tgtcgcaaag agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc
    12181 ggtcagacga atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttc
    12241 cgttggtgaa cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc
    12301 ctgtaaagga tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa
    12361 gagatcgagg actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat
    12421 tcgaagtact gatgatatta acgaagagaa aaaaagctct atcgctaatc ggtgcatttg
    12481 cgctgacatt ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt
    12541 tctttacttt gggactgatg actgcttttt atcattattt ctacaatcat gataaaaaat
    12601 ggctacgaac gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga
    12661 tttacccagc ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc
    12721 ttatttacta tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg
    12781 cagttttatt tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt
    12841 tagcttcttt gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga
    12901 ttggcgaatt tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt
    12961 cgaataactc tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc
    13021 catttgtgtt atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga
    13081 ttttttgtct gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa
    13141 tcactctgct gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt
    13201 gtttattatc gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt
    13261 ataaattcat tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga
    13321 aaatggataa ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga
    13381 ttttagcttt tgcattattt ggctggagac gcttgtttta cctcgctttt gccgccttag
    13441 ttatcgtatc tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa
    13501 aaacactggc aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt
    13561 ctgaagatga attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac
    13621 gcttttatcc agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt
    13681 attataatcg gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt
    13741 tagatcgtcc agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga
    13801 tcgactatgt gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt
    13861 tcacgcagct atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg
    13921 attatccaga tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg
    13981 ctagctgaga ataatcctga aatgttagta gaaaggagag tggagataat tcaagcaatc
    14041 gtacaaaaat ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttact gacgctagtc
    14101 ttttttgttt ggacagcagg gttaggtttt ccagcaactt tgtttatata taacaatagt
    14161 tcattactta tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa
    14221 ggcgtcgatt ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt
    14281 cgggaattaa gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt
    14341 tgtttagtaa ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc
    14401 ttttcggtct tcctcggaat cacgtttatc gtgtatttac agagatccaa gtaccagaag
    14461 gacaaagcat ctgggctcca ggcaattcgc tttctgatat ttggatcaat acgaatacaa
    14521 tcggaagttc tttgatgact cttgctttat tgatcagtgg atttgccagt tcttttgaac
    14581 gatggtatgt acgaatcatc ggtgcagtag cagttgttgc agcttttctc gggatttggg
    14641 tctgccaatc tagaggtgca ttagtcgcgt tgattgtttt tgcgatattg gatcttttac
    14701 ctaaatcgtt gatgcgtgtc attcgtgcgc catttattgc ttacacggtt acgattcttt
    14761 tagctttgcc gatttcttat ctggcggctg tctctgaaaa agtcaatttg tttaccggtc
    14821 gagaagatat ttggcataaa ttctatcaga cgctaggaga aaaatctgaa caaattttac
    14881 taggaatgaa aacatttatc ttccaacgag gaaaccaatt tttaggaaac cacaatagtt
    14941 ataattctat tttgaatatc tatggattga taggatttgg gattgctgct ttgctgctta
    15001 tcctttttat tggtcgctta acgttgaaag cagatttatc caacgggcag atgactttta
    15061 tctgggcctt ttttgcggtg atgatgcagt catttatgga ggatacattg acttcataac
    15121 catgggttcc gattatttat atcctgttgg ctatggccgt tcatcgatat gatgaaccag
    15181 aagttgcgga ggaattctat gttatggaag aggcatatga cgatatgact tatgatgata
    15241 catcttatga ggaacaacca gatagcgctc attcttccag gatccaacgc tatcattgat
    15301 aggcacaaaa
//
LOCUS       DARPZJ010000057        15258 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.060, whole genome shotgun sequence.
ACCESSION   DARPZJ010000057 DARPZJ010000000
VERSION     DARPZJ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.060"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..248)
                     /locus_tag="SLE23_002200"
     CDS             complement(<1..248)
                     /locus_tag="SLE23_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8469078.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRT"
     misc_feature    469..594
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            638..1162
                     /gene="infC"
                     /locus_tag="SLE23_002201"
     CDS             638..1162
                     /gene="infC"
                     /locus_tag="SLE23_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEI8469079.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            1234..1434
                     /gene="rpmI"
                     /locus_tag="SLE23_002202"
     CDS             1234..1434
                     /gene="rpmI"
                     /locus_tag="SLE23_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEI8469080.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1487..1846
                     /gene="rplT"
                     /locus_tag="SLE23_002203"
     CDS             1487..1846
                     /gene="rplT"
                     /locus_tag="SLE23_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEI8469081.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            2098..3405
                     /locus_tag="SLE23_002204"
     CDS             2098..3405
                     /locus_tag="SLE23_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HEI8469082.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAIFA"
     gene            3482..5611
                     /locus_tag="SLE23_002205"
     CDS             3482..5611
                     /locus_tag="SLE23_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HEI8469083.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKQQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            5586..6275
                     /locus_tag="SLE23_002206"
     CDS             5586..6275
                     /locus_tag="SLE23_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469084.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(6683..7369)
                     /locus_tag="SLE23_002207"
     CDS             complement(6683..7369)
                     /locus_tag="SLE23_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8469085.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(7505..7699)
                     /locus_tag="SLE23_002208"
     CDS             complement(7505..7699)
                     /locus_tag="SLE23_002208"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469086.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(7749..8189)
                     /locus_tag="SLE23_002209"
     CDS             complement(7749..8189)
                     /locus_tag="SLE23_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HEI8469087.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(8193..9038)
                     /locus_tag="SLE23_002210"
     CDS             complement(8193..9038)
                     /locus_tag="SLE23_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEI8469088.1"
                     /translation="MLINEQLVKRIITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            9187..10605
                     /gene="pepV"
                     /locus_tag="SLE23_002211"
     CDS             9187..10605
                     /gene="pepV"
                     /locus_tag="SLE23_002211"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEI8469089.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(10662..11609)
                     /locus_tag="SLE23_002212"
     CDS             complement(10662..11609)
                     /locus_tag="SLE23_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEI8469090.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(11832..12182)
                     /locus_tag="SLE23_002213"
     CDS             complement(11832..12182)
                     /locus_tag="SLE23_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEI8469091.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            12382..13461
                     /gene="pepA"
                     /locus_tag="SLE23_002214"
     CDS             12382..13461
                     /gene="pepA"
                     /locus_tag="SLE23_002214"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEI8469092.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            13605..13925
                     /locus_tag="SLE23_002215"
     CDS             13605..13925
                     /locus_tag="SLE23_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEI8469093.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            13947..14411
                     /locus_tag="SLE23_002216"
     CDS             13947..14411
                     /locus_tag="SLE23_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8469094.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            14616..15221
                     /locus_tag="SLE23_002217"
     CDS             14616..15221
                     /locus_tag="SLE23_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HEI8469095.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
BASE COUNT         4833 a         2815 c         3178 g         4432 t
ORIGIN      
        1 gttcgtggaa catgaagttc taacgtacca attcgagttg taaacgaacg atcgtagtaa
       61 ccatttcttt gtgattgccg ttcttctgaa cgttcatagg catttgcctg aatatattga
      121 tttcgttgtt cttccatcag ctgattaaac atgatagtca taagtgtttt tgcggtatca
      181 ttcgcaccgc tttcgtttat aattgcttga atttcttcgc tttcaaaagt aaaatgtact
      241 tgagtcattg atatcagtcc tattcgagta tgttttctgc aaaaaacatt gtactcctaa
      301 ctgagatcaa tggctttttt gatgcttcac ttttacacaa ttatatggac gtaatccggg
      361 aatcactgct agaaagtctg ctaatctaat cattttcaga aaaggaagac aaactgtatg
      421 aaaaacattg acaaaaagat tagtttttgc tatactatga tggttgagaa ataaaagcag
      481 aagcacccgc ttctcgcctt agttgataat gtcactgggc tagatagttt tcactggttc
      541 tattaggtga agtacgcgcg ggttctgtaa gagaactcgt ttttttattg ccgtttattc
      601 ggtaagcttt tctttctctc ataatatttg gaggtgaatg accatagcaa aggatatgat
      661 ggttaacgac ggcattcgtg cacgagagtt acgattgatc ggttcagatg gtgagcaatt
      721 aggagttaag acaaaagcag aagcattgaa tattgcagaa caagcaaact tggatcttgt
      781 gttagttgcc cctggtgcga aaccaccagt tgcgcgaatc atggactacg gtaaataccg
      841 tttcgaacaa caaaagaaag accgcgaagc gcgtaaaaaa caaaaagtga tcaatgtaaa
      901 agaagttcgc ttaagtccta cgatcgactt gaatgacttc aatacaaaac ttcgtaatgc
      961 acgtaagttc ttggaaaagg gcgataaagt gaaagcttct atccgtttca aaggccgtgc
     1021 cattacccat aaagaaattg gtcaaaaagt cttgaatcgc ttagctgaag aaactgcgga
     1081 tattgcaaca gtggaacaaa aagcgaaaat ggacggacgc agcatgttct tgacgctggc
     1141 accgaaaaac gacagtaagt aatttgaatg actaactggc tgttggacag ccgatagtcg
     1201 gataacgaaa gattttgagg aggaaatata gtcatgccaa aacaaaaaac acaccgcgga
     1261 tcagcaaaac gtttcaaacg tactggtaaa ggcggattga aacgcttccg cgcgtttaca
     1321 agtcaccgtt tccacggcaa aacaaaaaaa caacgccgtc aattgcgtaa agcaagcatg
     1381 gtttctagtg gcgacttcaa acgtattcgc caacaactag caaaaatgaa ataagaagta
     1441 caaataacag aatctgaaga tttattttta ttaggaggaa ttatacatgg cacgtgttaa
     1501 aggtggaaca gtaactcgta aacgtcgtaa aagagtgcta aaattagcaa aaggttacta
     1561 cggttcaaaa cacactttat ttaaaacagc aaaagaacaa gtaatgaatt catacaacta
     1621 cgcatatcgc gatcgtcgtc aaaagaaacg cgacttccgt aaattgtgga ttgctcgtat
     1681 caacgcagca gctcgtatga atggcttgag ctactcaaaa ttaatgcacg gtttgaaagt
     1741 tgctgaaatc gacatcaacc gtaaaatgtt agctgacttg gctgttaacg atgcagcagc
     1801 atttactgca ttggctgacc aagcaaaaga agctttggct aaataagcta aacaattata
     1861 aagaggaaag aagataacga aaagttatgt tctttcctct ttttttattt acaatcctcc
     1921 atcaaatgaa acaggacaat aacgtataag tctaaaatag cataattaag gttttttaat
     1981 tgaaaactga acatttatgg tcacccttta atgaaagcgc taactacata agttagaatg
     2041 agtttgactg atatattagt ttgcttatca gaaaaacaaa atggacggag gaataacatg
     2101 agtgatatta ttattggtat tttgttagtt atctcattct ttttcatggt ctggtactgt
     2161 gtaaaaggct acaacttgat ggtcggcttt gccatcatgg ctactgtatg gatgggatta
     2221 gcgctagtcg gaaacacgtt ttcaccaaac ccggcgatgg aagggcaagg agtaattgat
     2281 gtgttgacgc atatctatac gacggggcca gctgagtacg ccaaatcgat cttggtaaat
     2341 gtcttctttg gtgccttttt cgggcgtgtt ctagtagata gcggaatcgc agctaccctg
     2401 attcgaaagg tagttgaact tggaggggac aagccaagaa tcacgatgag cttactatgt
     2461 attgtaaccg ctgttatatt catgtcgatg acaggaatcg gaccagtgat ttctattgca
     2521 gttattgtgt tgccaatctt gatgtcatta ggtatttcag taccggttgc actgttctca
     2581 tttatgggct cgattatggc tggaatcttt gctaatatcg tcaatttcaa acaatatcaa
     2641 acgatttatg ctggtttcaa tccagcggct gaaagctata cttataatga ctatttccaa
     2701 attggtatga ttgggatgat tgtaagctta gttgtggtac taacggtcgc taatatatca
     2761 atgaacaaaa agaaacgcta tgcaatggca gcaaacgtac cagctgaagg tggcgacgca
     2821 ccaatgatct catggttagc cgtattatta ccagttttag gggtcgttct tttagatctt
     2881 ccaatcatct taggttttat tctagcaggt atctgggcat tgctgtttac tggaaaattg
     2941 cgcggaggtt ataaagaaat ctgtcgtcag tttgcgaaat tatttacaga tggcgcagta
     3001 gatgttgcac caatggttgg tttcttgatg accttagcga tgttcaataa ttcagctgcg
     3061 tatgcttctc cttatttttc agctattttt ggagattgga taccgcaatc accattagtc
     3121 ttggcaatcg tatttgctat attgacacca ctaggatttt tccgcggtcc aatgaatcta
     3181 gtcggttcag gctcagctat tttagctgtc gtattagctg ttaatccaac gatgtcgcca
     3241 gcctttttgt tcccgttatt tgcaatcaca acgattgctc ctcagcattt agatattaca
     3301 caatcttggg ttgcttgggg attaggttat acaaaagtaa cttctcgaga atatatgaag
     3361 aaatccatcc caactggttg gatcatcgga gcgatctttg cctgatcacg ttcttattgt
     3421 acgggaacgc ctagtaaaca aaacgtcgat aaaaacgatt agatgaatgg aggaaaagaa
     3481 aatgaaacgt tttgtgcgaa tgggaattga tgttggcggt acacatacga aagcagtcgc
     3541 aatcgataat gcgacgcacg aaatcatcgg aaaatcttca gtgaaaacaa cccacgatga
     3601 tgtccgtgga gtagccgcag gtgtcgttca gtcttttcaa aattgtttgc gggaaaataa
     3661 tatcagtcca gaagatgttg tgtttgttgc acattctacc acacaagcga ctaatgcact
     3721 gattgaagga gacgtagcaa aagtcggcgt aatcgggatg gcaaaaggtg gattagaagg
     3781 ttttttagca aaacaacaaa ctagattgaa cgatatcgat ttagggaata agaaaaaaat
     3841 agagattgtc aatgcattct tacctgtcaa acacttaaat gtagaccgtg tttcagaaac
     3901 gatttcttct ttagaaagag aaagagcgga ggtcttggtt tcttctatgg catttggagt
     3961 agataatggg gaaccagaac gagttgttta tgaagcagca tcggtaaaat cgatccctac
     4021 aacgatggct tctgacatca caaaattata tggattgaca agaagaactc ggacagcagc
     4081 aatcaatgca tctattttac caaaaatgct agatacggca acctctacag aagattccgt
     4141 acgagaagca ggggtcaatg tttctttgat gattatgcgc ggagacggcg gagtaatgga
     4201 aatcaatgaa atgaaaaaac gacctgtttt aaccatgctt tccggtccag cagcatcagt
     4261 catgggctct ttgatgtact tgagagcgtc taatggtgtt tattttgaag taggcggaac
     4321 aacaaccaat atcggggtca ttaaaaatgg acgtccagca atcgattatt caattgtagg
     4381 tggccaccca acatatatct cttcattaga tgttcgggtt ctaggtgtgg caggcggttc
     4441 gatggtacgg gctaatcagt caggaatcat cgatgtcggt ccacgttctg cacatattgc
     4501 cggtctagat tatgcagtat ttacggagac agaaaaaatc aaaggtccta aggttgaatt
     4561 tttctctcct aaagaaggag accctgctga ttacgtcaag gtagtgatgg aagacggaga
     4621 agaagtgact attacaaata catgtgcagc caatgtcctt ggattagtgc aagaagaaca
     4681 tttttcttat ggaaatgtcc catctgcacg aaaagccatc caagcattag ctgattattg
     4741 tcatacgacg gttgaagaca tcgcagaaca gatcatggaa aaatcctatg ctaagattga
     4801 accggtgatt ttagaattgg cagacaagta tcacttggag aaagatcaga tttctcttgt
     4861 aggtgtaggg ggcggcgctg cctcattgat tacttacttt agtaataaaa tgggtgtgaa
     4921 atattcgatt cctgaaaacg ccgaagtgat ttcttctatt ggtgtagcac ttgcaatggt
     4981 ccgagatgtt gtagaacgta tcatcccttc gccaagtaaa gaagatatac gatcgttgaa
     5041 aaatgaagcg atgaataaag cgattgaatc aggcgctaca ccagaatcga tcgaagtcca
     5101 cgtagaaatc gatccacaga cttcaaaagt aacggctatc gctactggtt ctacggaagt
     5161 gaaagcaacc gatctaacca aggagatcac aacagaagaa gcactagagc ttgctgcaga
     5221 ggatatgcga ttaaataaaa atgaagtttg cttattggaa aatacacctt tcttttatgt
     5281 atgcggcgaa cagaatcgtt caaaaaatgc tggaagtctt cggatcatcg atcaaaaagg
     5341 atttatcaag gtccaacgtg gacatgcttc atgtatgaaa acaactgcag ccaattatat
     5401 gacagctgtc gaacaacttt gggaagatat ggcagtttat caaactgaat tgattgcccg
     5461 accagaattt tatctctgct taggagcaag agtctctgat tttacagcga cggatctgga
     5521 acaactacag cttttgatgg atctggaagt atctactatg gaaccggagg aagaagtgat
     5581 cgtcgttgcc ggaaatatca aacaaacata agttagaaga gttactaaac gaattacaac
     5641 agatccccga agaaatttgg ggattctacc agtttcggcg agatttattt tggaaaaaga
     5701 ttcctttgtc caagcagaaa attcttatac aacaatcaat cgattgtggt atcgaaacgg
     5761 catgtagcat caaaaaaaag tacccttttg ccgatgtagg agaaatttgt gaacaaatgg
     5821 ctgttccaat cgtttcctgt gaatcagagc aaataaacga acgaatcact tttgcaactt
     5881 atgcagaaga tgaagggatt cgattgatga cggagccgtt agaaaaatta aaatgttcag
     5941 gactagcttc gatctctaaa gaaacagcgc aagctttgat tattggacat gaactatttc
     6001 accacatcga agcttctgtt aagggaattt atacgcaaag cgaaaaaatt gtgctgtggc
     6061 ggttgccttt ttatacacat caatcaaaca ttcgtgcatt gagcgagata gcagcgatga
     6121 gtttttcaaa agagatgaat caaagcgatt tttcgcctta tgtattagag gcagtcttac
     6181 tttggccata taatgaaatt cgtagccaag ggatcttaga agaaataaaa aaaatagaaa
     6241 aaagatgtac ggagtatgat ttagattaca aataaagaga ctgtgacaaa agtcgtgtca
     6301 cagtcctttt tttccgaata aacgatgttc tcctgtcaac tcctcggtca caagtcaaaa
     6361 tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg gagatgaacg
     6421 gcaggctcac gacctcttgg aaaacggtgt tcaaaagctt gcatctgcgg taataagtcc
     6481 agccaagtta aaaacataag aagctatttt tacttggctg ttcttattac ttgatgcagg
     6541 gcagcttttt cacaacctct caataaacgg tgtgcaatca gctgaccctc ggtattagct
     6601 caaaaaaaac ggcaaaatat gaggaactat tttgccgttt ctttctctaa tactcaggtc
     6661 aaaacgctga ttccaaaacc tcttatttga tgggtctgtc ctgaatatct tcaaaataat
     6721 cggggtaatt atgaatcacg tattcttgct cctcgataat catatgtaaa tgcatcgtgc
     6781 aaagaaatcc gacttcatca aagttatgat caatcattga ttgaagcatt gtctgatgtt
     6841 catctaatac tcgaccccag tctaattctg aaatcgtcaa acgtaaccat ctgaaacggt
     6901 tcaagtgcgt actataactt tctagccaat cccaaatttc tcgttttcca gcaatttcat
     6961 aacaagttcg gtgaaaatca gtatccaaat caaaaaaagc ttttttattt tgagcgatta
     7021 ctgcctgatc ggtttgttct agtatttttt ctagtttagc ttgatcttgc ttggtcattt
     7081 tcgcactgca ttcttgcagg atcggttttt ccaacttttc ccgcgtataa cgggctaatg
     7141 aagcagatcg gatatcgatt tttgaaacat aagtgccgga ctgtggaatg gtttttacaa
     7201 gctcttgatt gcgcagttgg atcagtgctt ctcgaatcgg tgtacgcccg atagctagtt
     7261 gttcttctaa cactttatcg gagattttac ttccaggtgc taactcggaa taaatgattt
     7321 gtttacgtat agattcataa gcttgctgtt gcaaattatt gataaccatt taaccttcct
     7381 ttctatgcag atataatcta ttataacata aatcgcttac aaatcgtgtg ggcataaaaa
     7441 cacagtctgc aaaaaaagcc ctgataggca tgcctattag agcctcgaaa agaaaaatat
     7501 tgaatcaatc tggtcgtacc tcttgtatcg gtttgacacg accgccgatt cttttagcaa
     7561 aagcttcgga ttcttttttg tctttgaaaa tgagcagatt gtctaagttt ttttcccgag
     7621 tgcgacagcc agttttatcg atgtaaccgt gcattacttt aacgacatac atggggatca
     7681 cctgcttttt tcttttcatt atacgaacta ctcgacacaa tacaagaaaa atgcttagac
     7741 ggtctttatt aagaatttac atcatccaaa gaagcgtacg cttggaataa ctgatctaac
     7801 tccggattga ctttgctcag cttcactaat cgttgcgaat cagaaagtaa aaaacagtgt
     7861 ttactactgc cagtagtttt taattttttg tcttcagttc ccacaatttc gtagctaaaa
     7921 tccaaccgtg tccccgtata cttttggata gttggatgga tgctcacttt ttctccgtaa
     7981 tggatcattt ctttatagct gcaatttact tccagaacgg ggatgatgat cccagattct
     8041 tcgatttttt tatagggaaa ccctagatgt accaataagg ctacccgagc ctcttcaaac
     8101 cagcggatat aattgctgtg atgaataatc cccatttgat ctgtttcata ataaaaaggt
     8161 tctcgcacat aacctgtaaa tttctccatg actcatgcct cgttttccat tgatttttta
     8221 caaaaataat tcatccattt cggaagtgct tcgctgattt gtgtcggcaa aacaatatat
     8281 tgttcttttg ccagctggtc tccaatgaaa ctatgaagat aaatagctgc tgcaatcgtt
     8341 tggtcatttt gaggaaactg ggctaaaaat cctgtgatca tcccagctaa agtgtcaccc
     8401 atgccgcccg ttgccatagc agcagaacct aaaggattgg tgtagaagtg ctggtgacca
     8461 taaatttttg tctcatgact tttcaaaacg agcacagcac cgatttcctg ttgcttcttt
     8521 ttgttttctt tatcccgttg ttcttgtatc ggtagagaac tcaaccgttg ccactccatt
     8581 tgatgaggtg taagtacagt ttgttcggga tagggtagca aaagatgatt agcagcaagt
     8641 aaacttaaag cagagccatc aatcaccagc cattgttctt ttgattggtt ttctagtact
     8701 tgtttgaaac gttccaaact cttagaagaa gtacccaatc cgggaccaat caagagtaca
     8761 tctgcttgct ttattacgga aagaaactgg tcagtatccg tccaaactac aatcattgct
     8821 tctggcagat gactgtgaag agcactccga tttttttcat cagttactac agtcgtgaga
     8881 cccgctccgc tgtgtacggc agctaaagca ctcataatga ttgctccgcc atattgttca
     8941 ttgccgccaa tcaaaacgat acgtccaaat gttcctttat gtgaaatttt tggacgaggt
     9001 gtgatgattc ttttcactag ttgttcgttt atcagcatct aaaaacctcc ttttactcat
     9061 tatagcgtat atttttttta gagaaaaaca gataagaaaa ggaattgtca gattttttga
     9121 actatttttt tctgtaattt gtggtatcat gaacacgaag acttaaataa gtggaggatt
     9181 aactttatga caattgattg gcaaaaagaa gtagaagcac gtaaagaaga cttgcttgaa
     9241 gacttgaaaa atcttttacg tgtcaacagc gagcgcgatg actcaaaagt aacaccagat
     9301 gcaccatttg gacctggacc tcgcgacgca ttgaaacata tgttagctta tggcgaacgt
     9361 gatggattta aagtaaaaaa tgtcgataac tatgcagggc atattgatct tggcgaagga
     9421 gacgaaacgc tagggatatt tggacacatg gatgtcgttc ctgcaggaga tggctgggac
     9481 acagatcctt atgaaccagt aatcaaggat ggaaagatct ttgcacgcgg atcaagcgat
     9541 gacaaaggtc caagtatggc agcttactat gcgatgaaga tcattaaaga acttgacttg
     9601 aaactatcaa aaaaagttcg cttcgtagtc ggcagcgatg aagaaagcgg ctggggcgat
     9661 atggcttatt atttcgaaca tgaagaagaa ccagattttg gtttctcacc agatgctgaa
     9721 ttcccaatca tcaatggtga aaaaggaaat gtttctttag ctttacgctt caaaggcgac
     9781 aatgcaggag attatgtctt gaaatctttt gtttccggac ttcgcgaaaa tatggtgcca
     9841 ggaacagcaa ctgcagcact tcaagtacca agtgcagatg cagctatcgc gatggaagaa
     9901 gcattttacc aattcatcga agcaaatcca gtaagcggaa cgattgaagc ggacaatacg
     9961 tatgtaaaaa tcgaattagt tggtaaaggc gcacatggtg caagcccaca atctggtatc
    10021 aatgcaggtt ctttcttggc attgttctta gataactatg aattcctagg atctgctaaa
    10081 caatttatcc atgtagcagc tgcttatgtc catgaagatt tttatggaga aaaactagga
    10141 gtcgcttatg aagatgaaaa aatgggcaaa ttgacaatga atgctggact atttgctttt
    10201 gaagaaaatg gtacagagga agcgaacttc atcaatatga atttccgttt tccaaaaggt
    10261 gtaacagtag acggattgca aagtgacatc gaacaaacag tggggcaaga aggcgcaaca
    10321 gttactcgag gtgctcgcgt aatggaacca cattacgtac caatggatga tccattggtg
    10381 gctacattat tgcaagtcta tgaagaccac actggagaaa aaggctacga acaaatcatc
    10441 ggtggcggaa cttacggacg tttgttgaaa cgtggcgttg cttatggagc gatgttccca
    10501 ggatatactg atacaatgca tcaagcaaac gaatttatga gtcttgatga cttgttcaga
    10561 gcaacagcaa tctatgcaga tgccatctat cgtttggcga aataattaat taaaaagagg
    10621 atcaagaatt gcaaattatt tttgcagtct tgatcctttt tttactttct actgtggtat
    10681 tcatgataaa catgatatag attcaattca tattctttct tagcgttcgt gacgactgta
    10741 tccaaaatca accctgttac taatgaaaga agtgctaaag tcatcaatcc agtacttaaa
    10801 atcgcagaag ggatgcgtgt aataaagctt gtcagcatat attcgcgaat cacaggaatc
    10861 cccgtgacca atccaaataa aaagaagaag atggtccaaa tcccaaagaa aagcaaaggc
    10921 ttataatctt taaacatttt aataatcatc atgatcactt tgaatccgtc agagaatgta
    10981 ttcaattttg attcgctgcc ttcaggacga tcacgataat cgattgggat ttcaacgaac
    11041 ttgaattttt tatctaaagc atggatcgtc aattccgttt cgatttgaaa accagaactc
    11101 ataataggaa aacttttgac aaagatacga ttgaatcctc gatagccggt catgacatca
    11161 agaatttttg ttttatacat tctagtaatt gtatttctaa caaggttatt tccaaaatcg
    11221 tggaaaggtc tcttattctc atcaaagtag gttccatttg ataggcgatc accaatgacc
    11281 atatctgctt caccagaacg taatttctcg agcaaaccat gtacagcttc tgcaggataa
    11341 gtatcatcgc catctaccat taaataatag tcggcatcga tatcaaagaa catttggcgg
    11401 atcacatttc cttttccttg acgaggttct ttttttacga ttgctccacc ttgaacggcc
    11461 aattcgtatg ttcgatcggt cgaattatta tcatagacat aaatatctgc ttctggtaat
    11521 tctcgtttaa agtctgcaat gactgttgaa attgttgctt cctcattgta acaaggaatc
    11581 agaacagcaa ttttttcttg ttgttccatt tttcactctc cttaactata gaaaacaaaa
    11641 gctaaattaa aaatacctca taatcaaagg aaatgctagt ttttcccgct aaatatcatt
    11701 tatttaaaaa gaaaatactg gaatatatgt ttggaaagct ctatctaaaa aaccacccac
    11761 tacaaaagaa ggacatgata cctctctttt gaatagtggg tgcgtattcg ttctctcact
    11821 tttttgacgt attaatctgt tgcacctttt tttcttgaaa tttctaatac ggttcctgta
    11881 tgagcatctg ctaaaaattc ataataaaca gtttcgccat cttctattcg agaaagacct
    11941 ccccgataag cactcgaccg aacggcgaat ttcctaatag gttccttttc aaaagagatc
    12001 caagaacctt cgattgcacc ttcttttaga aaagatgact tgatattttc aagtacttgg
    12061 tctgctgaca atactttttt gcgatgatac caaatcgttg aagctacccc gctcaataat
    12121 cctagaccga ttccaactgc taacccgcct ttaaaatagc ttagttcgct ttcttcatac
    12181 atgtggacat acctccttct tctcacttgt tactccttgt gcttatttta ccacactctc
    12241 atattttctt tgaaataaat aaccgctacc agaaaaaata agctataata aatacgatcg
    12301 gtctgcagaa aaaatcatat tttatccgca gatcaatata agtctgagag gagtttagtc
    12361 tgaaatttag acgaatagca tatggaagaa aaaacatttc aacgaatcaa agagttaaca
    12421 gaattacaag gaacaagcgg ttttgaacaa gatgttcgcg cttatatgga aagtcatatg
    12481 gaaccgctgg tagatgagtt acagttagat ggtttgggcg gcatttttgg tctgcgccat
    12541 catgaagaag cggatgcacc ccgtgtaatg gtcgcagcac atatggatga agtcggattc
    12601 atgctgacac aaatccaaga aaacgggctt tttaaagtcg tacctctagg cggctggaat
    12661 ccttacgttg tttctgctca gcgttttaca cttaaaacct ctactggtaa gaattatcca
    12721 tgtatttctt cttccgttcc cccacattta ttgcgaggaa caagcggaca aaaatcagta
    12781 gaagtaaccg atattttgtt cgatgctggg tttgaatcaa gagaagaggc aatgagttac
    12841 ggtgtccttc caggagacac aatcgttcct tacgctgaaa cgatcaaaac agccaacgga
    12901 aagaatatta tcagtaaatc atgggacaac cgctatggct gtacaatggt attagaagct
    12961 ttagaagcgt tgcaaaatga aacattaggt catacattga ttgcaggcgc gaatgtccag
    13021 gaagaagtag gcttgcgtgg ttctaaagct tctgtcaata aattcaagcc agatctgttc
    13081 tttgcagtag actgctctgc agcagatgat acagtgacga aaaatggcac attcggacat
    13141 ttaggagaag gtacattgat gcgtatccaa gatccaggtt tgatcatgct tcctcgtttg
    13201 cgcgagtact tgctggatat cgctgaaaca aacaatatcc cttatcaata ctttgtttca
    13261 aaaggcggta cagatgcagg tgctgctcat acacaaaacg aaggaatccc aagtacagtg
    13321 attggcgtag tgggacgtta tatccatacg catcaaacga tgttcagtat tcgcgatttt
    13381 gaagctgcac gagaaatgtt gattcaaaca ctgaaaggtt tggataaatc aacagtgaat
    13441 acgatcgtat acggaaaata atgcgatagt gaaactataa aatctggcaa aagattgctt
    13501 tttgccagat tttttttata aaaagaggat caatgtttgt tagttcgaaa gaaaggtgta
    13561 taatttaatt gaaaaataca taaacagaaa gtagaggaca aagaatgatt atcccaaata
    13621 gtttagaaga attagcaggc tacgtagaaa ctggaaagag tgtatttttc tttactgccg
    13681 gctggtgcgg agactgccgt tttatcaaac cgcaaatgcc tgaaattgaa aatgactttt
    13741 ctgattggca atttattgaa gtagaccgtg acaagtacat agatgtagcc gctgaatgga
    13801 acatttttgg tatcccaagt tttgtcgtga tccaagacgg aaaagaatta ggtcgtctag
    13861 tgaataaaga tcgtaaaaca aaacaggaaa tcgaatcgtt cctagaaagt gtaacaaaag
    13921 gctgacatct gttaggaggg gtcaagatga atcaagaata taagaatatt ttagtaggta
    13981 tcgacggtag tgaacaagca cttgctgctt tcaaaaaagc ggtagaagtg gctcgccgta
    14041 ataatgggaa agtatatgta gcaaacgtaa tcgatcagca attttataac tttatgggct
    14101 atgcacctat tgatcaaaat ctagtcgatc agcaaactga aacagccaag gaaatgatcg
    14161 aagaatgtaa agaatatggg aaatctgttg attacacaaa tatagaagga attattgcat
    14221 atggttctgt tcgtgaatcc atggcagtca aattgccaaa aaaatatgag atcgatctaa
    14281 tcatggttgg gcagtcaggt ctaaatgcag tcgaacgctt tatgacagga agtgtagcca
    14341 gctacgtgat acgtcattca ccttgtgatg tcttgatcgt ttctgacgaa gaagaacagc
    14401 caagtaatta agcaagtgga acttgtacga cctttttaat caattaacta aaacagtaaa
    14461 gggactgtga caaaagtctt gtcacagtcc cttgttacga ataaatggtg ttccagaaga
    14521 ggcttcttcg gaaataaagc atgaaaaaaa tttcatgcag tgaatgcaat tttttgttaa
    14581 gataaatctc agcaaaggat aatggaggaa agaacatgat ttttgcttat aacaaagcac
    14641 acgtcggaga caccttgatg gttattatag ccgacgataa aggaacagaa aacactgttg
    14701 aacgcaaatg gaatgttgct cggatcaaag atgaacaagg tcaagttgtt gcttggaact
    14761 ttttccatat ctccgatcat ctaacaatcg aagggaacgg ccaagtaagc ttaacagatg
    14821 aggaattagc gaaattgaat cgattgatca aagaagcagg attcgaagaa cagcttgaag
    14881 ctgatcatga accgaagatc gttgtcgggt acgtaaaaac atgcgtccca catcctgatt
    14941 ctgaccattt atcgattact gagacagaag tagacaatgg tacagtattg caaatcgttt
    15001 gcggtgcacc caatatcgaa gctggacaaa aagttgtcgt tgcaaaacca ggagctatga
    15061 tgccagatgg aatgatgatc tggccaggaa ctttgcgagg ggtagatagc tatggaatga
    15121 tctgttccgc tcgtgaattg catttgccaa atgctccagc aaaaaaagga atcttagtat
    15181 tgcctgagga tgccgtagtc ggagaagcat ttccaaaata aagaggttgt gacaagtctt
    15241 tgtcacaacc tctttttt
//
LOCUS       DARPZJ010000058        15231 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.061, whole genome shotgun sequence.
ACCESSION   DARPZJ010000058 DARPZJ010000000
VERSION     DARPZJ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.061"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            278..787
                     /locus_tag="SLE23_002218"
     CDS             278..787
                     /locus_tag="SLE23_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8469096.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="SLE23_002219"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="SLE23_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEI8469097.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="SLE23_002220"
     CDS             2322..3302
                     /locus_tag="SLE23_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8469098.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="SLE23_002221"
     CDS             3424..4842
                     /locus_tag="SLE23_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HEI8469099.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="SLE23_002222"
     CDS             4913..6382
                     /locus_tag="SLE23_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8469100.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="SLE23_002223"
     CDS             6392..6859
                     /locus_tag="SLE23_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8469101.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="SLE23_002224"
     CDS             6895..7767
                     /locus_tag="SLE23_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8469102.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10383
                     /locus_tag="SLE23_002225"
                     /pseudo
     CDS             7848..10383
                     /locus_tag="SLE23_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            10539..11312
                     /locus_tag="SLE23_002226"
     CDS             10539..11312
                     /locus_tag="SLE23_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8469103.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11305..12096
                     /locus_tag="SLE23_002227"
     CDS             11305..12096
                     /locus_tag="SLE23_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8469104.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12106..12597
                     /locus_tag="SLE23_002228"
     CDS             12106..12597
                     /locus_tag="SLE23_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8469105.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12615..13025
                     /locus_tag="SLE23_002229"
     CDS             12615..13025
                     /locus_tag="SLE23_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8469106.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13029..14429
                     /locus_tag="SLE23_002230"
     CDS             13029..14429
                     /locus_tag="SLE23_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HEI8469107.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14452..14826
                     /locus_tag="SLE23_002231"
     CDS             14452..14826
                     /locus_tag="SLE23_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8469108.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5286 a         2135 c         3047 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcggatcgc aagggaaaca aataagttgc tgaatacata tgtttatgag
     9421 gctttcgata tgccaattga aggtgagact agtgacttaa ttaacctaat caacaatttt
     9481 tgtaaaagta tagatacgac gaatggactc attctgctag ttgatatggg atcattggaa
     9541 caaatgtatg aaaaaattga atccaatgta ataggtgatt tggtaatttt aaacaatgtt
     9601 tctacagctt tagcgattga atgtgggatt caagtttgcc aaaaaaagcc aattagtcat
     9661 ttttaccaga tggattttga ttcgtttcaa gttaaagttc agtattataa aggattatca
     9721 caaaagaaaa atgtaatagt atcttgtctc tctggtgagg ggatttctga aaaagttaag
     9781 gatattttaa aacggtatct cgataatcaa gtggagattt tgatttttga ttttaacgca
     9841 ttaaagaaaa tagcaaagga aaaagatact atgattttta agaatacaat ttgtgttctt
     9901 tcaaccactg aattttacat tcaaggaatc gattgtttaa atttagaaaa tctaattaat
     9961 gggaatcaaa ccttagaaaa attaaataag tatatggact cggatagctg tgagttctgc
    10021 ttaaatgaat tagttaaact ctttactatt gaaggcgcta gtactaagct tcgcttttta
    10081 gattccaaaa aagtattcaa tgagatagaa aaagtactat atttgtatga aaaatattac
    10141 gatgtcaaaa tcccaagttt tctgagaatt aatctatttc tacatctttc tggaatgatt
    10201 gaacgaatta tgattggtga tggaataaca aatgaacatt tgaaagaggg agcgcaacta
    10261 tttgatactt ttttaaatgt atcaaaagat tttttttcag aaatcaaaga tatttactgt
    10321 attgaaatac ccaaaggaga gtatgagtta atctatacaa tttttgagca gactattttc
    10381 taaatagcat actagcgtct aaaaaaatga aagggtgtcc aaagtatatt tagacgctca
    10441 tttaattaat atttactgta ttttcccgct ttattggata atgttagttg gcacagtaat
    10501 tgcttatata aaagtataag aagaaaggag agaacaaaat ggcgttttgg caaacatttt
    10561 tagttgtgtt gtatggattt ttcattaact gggataagga agggcccaaa atcggaacct
    10621 cccaacctgt cgttgcaggt ttcttgaccg gacttattat gggagatatt caaactggac
    10681 tttatatcgg tgggactttg caattaatga cactaggtat tactagtttt ggtggtgcat
    10741 cagtaccgga ttatcaaaca gcagcattga tcggtactta tttagcaatc tcaactaacc
    10801 aggatgcttc tataggaata actttagcaa taccggtagc aatgttaatt gtacaactag
    10861 atgttctaaa gtggtcaaca aacatttttt ttcaacaaaa ggcagaaaaa ttcgcacaaa
    10921 aagaagatta tcaaaaatta gagtggatgc aatatttggc atcaattaat acaagctttg
    10981 tatctggaat tcctgttttg ttaactgtga tattaggccc aacgttagtg ggaagtgcaa
    11041 tcaattatat tcctgaatgg gttaccggtg gtttaaaggt agcaggggga ctattacctg
    11101 ctgttgggat aggaatgcta cttaaatatt tacctacaaa agattacttt gcctatttgt
    11161 tagttggttt cgttttggca gtttatttcc aaataccaat tttagggatt tcgttacttg
    11221 gcgctgcaat cgcactaatc gtatataaaa atagatcaaa taatactcaa gtagcaccag
    11281 ctgcaacagg aggttttgac gaagatgaat aagaaactga caaaaatcga caaacaagta
    11341 attttccggt ggattctcaa tggtgcaact tcattaaatt atgaaaaaat ggaagggttg
    11401 ggttatgcgt attctatgct tccttttatc aaggacacat ataaagatga tcctgaagga
    11461 atgaaacaat ccgttttagc tcacttacaa ttttttaaca ctacgccgta tacagcgcct
    11521 tacattattg gtatgaatgt tggaattgaa aaagaagaaa aaaataagtc tttggaagca
    11581 gtaagtgctc tgaaaacagg tctaatgggt cctttagcgg gaattggaga tagtgtattt
    11641 gtagttattc catggactat ttttggagca attgcagcta atatggcatt ggaaggtagt
    11701 tttgttggaa ttattttgtg gatactggca tcaattttat taaggattac tgcttatcct
    11761 ttataccttg ctgggaaaga atcgggtgcg agcctactaa ctcaaattga aacaaaatta
    11821 aagtctatta ctgatgcagt atcaatttta gggttaatgg tggtcggtgc actcattgcc
    11881 acagttgtaa aagtgaatgt tggctttgaa tttaaacaag gcgacttaac aatgaccgga
    11941 aatgaaatct ttgatcaagt tatgcctggt ttattacctg catgtgtagt agcaattgtg
    12001 tattatttgt taggacgaaa ggttaaacca gtttatgtaa ttctattaat cttagtagtt
    12061 tctattgcgt taagagcgtt aaatattttg aagtaggtgt tgaatatgga tgaaaaaatg
    12121 aaaggtatta tacatgttcg tattgatgat cgaatgattc atggacaagt agcaacacaa
    12181 tggacaaatc aattgagtgc taacagaatt atggttatta ataatgaagt agccaatgat
    12241 gacgtaaaaa aagctgtagt tcgcctcgct gcaccaccta atgttagaac ttcaataatt
    12301 acaagggaag tagcagttaa aaatattctt tctggtaaat atgaaggaca aaaagttctt
    12361 attgttgcag tttctccaat cgatgttaaa tttttgattg ataacggttt accaataaca
    12421 agtgtaaacg taggaaattt atcaagaagg aatggaacag aacgcatccg tccgacgata
    12481 aatattactg aagaagagag agaggctttt aaagaactaa ttagtgatgg agttgaagtg
    12541 acagtgatac aaactcctag agattcaaaa gaatttttaa aggattttat ttattaagaa
    12601 cagaggatga gtggatggag tttataatta catctcatgg aaatattgcc attggatttg
    12661 tagatacatt aaaaatgttt tttggcgata atttaaattg tcatgtggta acacttggag
    12721 atgcaggcat tgaagaattc cgtgaaaaca ttgaaaaaat agtttctcaa gtaaaaaatc
    12781 aagaagttat ggtatttgct gacttgattg gtggaacacc tttcaacgaa tttgctaaaa
    12841 gaagtgaagt atttcaaaat gggtttcaac ttcttggtgg catgaattta ggaattttga
    12901 ttgaggctgt caatttgaga ttacaaggaa aaaaaagcga tgatatcatc gaaaatctaa
    12961 gaaatatgaa tacaattgcg tgtcttgcag atatgcaaag acatactaac gaagaggatg
    13021 agtgataaat gcaaaaaatt ttttacaagc ctaaagattt ttggtttggg gattgcatgc
    13081 ctttttataa agatggaact ttttatctat ttcatcaacg agatacgaga aatcctaaac
    13141 ctttaactga tccttttggg tggtcactag ttacaaccac tgattttgtg aaatttgaag
    13201 aatacgggga agtaattcat cgtggtggca acgatgacat tgatcaatac atttacgctg
    13261 gaagtattgt ccaaggaatc aatgagtatt tagctttgta tactggacat aatcgcaaag
    13321 ctaagttgga tggaaaaact tcagaagtgt taatgattgc aagttctaaa gatttaattc
    13381 attggaaaaa ggatggcgaa gcagcaaaac ttgttcctca agaaggatat gataagaatg
    13441 attggcgcga tccttttgca atttttgatc aagatcatgg aaaatacgtt ttgatactag
    13501 gagctagaaa accagcaagt aagaaaaagc cgacggggag attggtctat tttgaatccg
    13561 aagatttaaa agattggaat ttcaaaggag actactgggc taataatgaa tttaacatga
    13621 ttgaaatgcc tgatatattt gaaattgatg gaacgtggta tttacttttt tcagagtatt
    13681 gtgaagataa aaagactaaa tatcgagtcg gagcaggatt attttcagat tggaaatcac
    13741 cagtagacga agctttcgac ggaaaagcct attatgcagc aagaacagtc ggaactaatg
    13801 aaactggccg ttttctaact ggctgggtgg caacaaaaga aggggagaac gatcaaaata
    13861 actgggattg gggcggtgca cttgttccac atcaaattat tcaaaagaca gacaaaactc
    13921 ttggtgttaa actgcctgaa aaaataattg agaattttaa agaaatcact ccattttcaa
    13981 gttttaagtt agagaaagaa tttggaaaaa aagaaagagt aattgttcct aaaatcgaag
    14041 attattttct atttgaaaca actttgacta ttacatcgtt aacaaaggag tttgctttaa
    14101 aattatttgt agatagtgat actcaagaag gatacgaatt tcgtatttca ttgattaata
    14161 atcagcttac tttcggaaaa actccgaact atccttggcc tcaaatgttt gataaggggc
    14221 tgcaacgacc actatttttg gaaataggca aagaatatga actaaagtta attgttgatg
    14281 atacgatagc tgttttatat attgataatg ttgctttaag tactagaatg tatgataaag
    14341 tcggaacagc attaagtatg actgttacgg agggagcaat caaggtagat aaactagact
    14401 attcaataaa ttatgaatgt ggattttaaa acaattgaag ggatgatgta agtgaaatta
    14461 aatggtttac aacatattgg aattccaaca aaagattttg gagcttcaaa aatcttttat
    14521 gaatccttag ggtttagtct gattaatgaa gaaatgaatg tgggaagtaa agtcggcttt
    14581 ttcgagttga atggaacgat aatagaaata tgggaagata aaactactga gtgtagagga
    14641 gccattgatc atctagcatt agatacggat gacatagatg aggtattcaa ttcaattcaa
    14701 gatttaggat atgaattatt agataaaaat attatggaat taccgttctg ggaaaatgga
    14761 atccgttact ttaatttcta cggaccaaat catgagatta tagagataag ccaaatgaag
    14821 aaataaatag ataacgaagt gctctaagtt ggtatgaacg aaaagtactt cattttttgg
    14881 tatcagcatt tcaatagttt aatgagaatt tactatttca aattaattca aagtgacagt
    14941 attttttact tatttggttt caaattttgt aatccttcct atttattgga atacactcca
    15001 cattttgtat acaagtcata tcatgtttta gcaaagctct taccaagcaa agttataatg
    15061 atgttttcca aagtttgatc tttcgatgga ggctaacaca tattttttgc aggacagcca
    15121 aaattagatg tatagaatag agtctgtgag gcgtatagac agtttattgt ctgtatgcct
    15181 ttttttattt tgaaaaattt ttagtatttt tcgaaaaatg ctcactccta g
//
LOCUS       DARPZJ010000059        15141 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.062, whole genome shotgun sequence.
ACCESSION   DARPZJ010000059 DARPZJ010000000
VERSION     DARPZJ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.062"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..344
                     /locus_tag="SLE23_002232"
     CDS             <1..344
                     /locus_tag="SLE23_002232"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469109.1"
                     /translation="NIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQDK
                     KNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQKK
                     RDNNDQYLPKK"
     gene            425..1045
                     /locus_tag="SLE23_002233"
     CDS             425..1045
                     /locus_tag="SLE23_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469110.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1746..2030
                     /locus_tag="SLE23_002234"
     CDS             1746..2030
                     /locus_tag="SLE23_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469111.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2033..2950
                     /locus_tag="SLE23_002235"
     CDS             2033..2950
                     /locus_tag="SLE23_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8469112.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            2943..3725
                     /locus_tag="SLE23_002236"
     CDS             2943..3725
                     /locus_tag="SLE23_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469113.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3726..4406
                     /locus_tag="SLE23_002237"
     CDS             3726..4406
                     /locus_tag="SLE23_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8469114.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4399..5295
                     /locus_tag="SLE23_002238"
     CDS             4399..5295
                     /locus_tag="SLE23_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8469115.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5490..7139
                     /locus_tag="SLE23_002239"
     CDS             5490..7139
                     /locus_tag="SLE23_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEI8469116.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7733..8668
                     /locus_tag="SLE23_002240"
     CDS             7733..8668
                     /locus_tag="SLE23_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469117.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8661..9431
                     /locus_tag="SLE23_002241"
     CDS             8661..9431
                     /locus_tag="SLE23_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469118.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            9847..10830
                     /locus_tag="SLE23_002242"
     CDS             9847..10830
                     /locus_tag="SLE23_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HEI8469119.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11277..12311
                     /locus_tag="SLE23_002243"
     CDS             11277..12311
                     /locus_tag="SLE23_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8469120.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTRAGS
                     NQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILV
                     INGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGI
                     DQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMFA
                     KTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLG
                     KVVVSGPFNG"
     gene            complement(12400..12723)
                     /locus_tag="SLE23_002244"
     CDS             complement(12400..12723)
                     /locus_tag="SLE23_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEI8469121.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12710..13417)
                     /locus_tag="SLE23_002245"
     CDS             complement(12710..13417)
                     /locus_tag="SLE23_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEI8469122.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13503..13844
                     /locus_tag="SLE23_002246"
     CDS             13503..13844
                     /locus_tag="SLE23_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HEI8469123.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14015..14863)
                     /locus_tag="SLE23_002247"
     CDS             complement(14015..14863)
                     /locus_tag="SLE23_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469124.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4854 a         2579 c         3200 g         4508 t
ORIGIN      
        1 caaatataaa aactagtacg aaattaattt gtaaattatt taagcttgat aaaataagca
       61 atatcgatga tgtaaagtcc aagatattaa caagaaaagt aagcgaacca gtaaagctaa
      121 cggcacaaga taaaaaaaat ggaattgttc tttatggtga tgatgcaaag tataactata
      181 attgggatac ctcctcagaa gctgaggtat taagtattcc tactaccgat acttcagggg
      241 aaaaagtcac ctttaaaata aattttataa cggcaatttc taagttggag tatgggaagc
      301 aaaaaaagag agataacaat gatcaatatc tacctaaaaa ataacgaatt aatgatgcat
      361 atgttaaagt tgtttttttg aattaaacaa ctcaatttat tcagttatat gttcatcgca
      421 gcaagtgaac attaatcgag ttataaaatt aataggagct aaaaatataa ataaagttcg
      481 atcagaattt atttttccag aagatttttt taactggttt ttttatcaat tcagtgaatg
      541 caagcgactc ttaggtgaga attattactt aaaaggaatc ggcggattta tggggaatgt
      601 ggctgatgaa caaaatatta taaaaggaat atctgaacaa acatcagagc ttacagtaac
      661 taaagcattt ataagtaatg gtgaaagttt gaaaaatgta actgcgcgaa ttagaaaaga
      721 aaatgaagta gacattgttt ttggaattga ccatgaatgt aattcagtga tatatgtaac
      781 acaatcagca aatttaattc tttttgagaa tggttgcaag gacgatttta tggtggtcta
      841 tttgtacgat atactaattc caaaacttcg ttccttatat atgtcttctg aaagtatttt
      901 tgtgagtgaa caaaagggat ctttctcgaa aaaaataggt attgaagtaa ttgaatcgat
      961 tatgtgtcat aatcatatta cgctagaaga attagaaatt ttgatagggc aaaaaaataa
     1021 taacacgaaa atacaagttt cttagaaatc attttttatt gagatatcta gataaatgat
     1081 ttattcttca atcaaccaac tcgccaagct gaggtaatgt tttgaggtaa tgataacata
     1141 caacttttta taccctagta aaactctata aacaaagact tattaatttc gcatgaaata
     1201 cattcctgta aaatgcaata aaatagagtt ttgtttaacc aggtcttaag aaagcccgta
     1261 aagcttcaca gttctcaaaa cgttaattgc gattatcgtt cgagttcacg agttacgaga
     1321 atcgtactgg gcgaagcaat gctgagcgca gttaccttaa tcctaacttt tctggcactt
     1381 tccacaattt ggaaagtgcc ttttttgtgt ttttagctat gttaataggt aggattcttg
     1441 gtctataata tcattcgatc tataaacaaa cgggaaaaag ataaagtatc atcaaacaat
     1501 attatttatc cgcttctgag gttgtgacag aagtggtcag cttcaagaaa taagaaggaa
     1561 tttacaaaaa ttgcttctca tgtttgataa atattgtgac ttgtgaccga ggagttggca
     1621 ggagaacacc gtttattcgg aagaagggat tgtgaaaagt cttttgtcat aacctcttat
     1681 ttggtagcta attgtaaatc ccaaacggca tgtattattt ttcataagtc cgtttttaag
     1741 gattaatgtt ttcttttgct ttttatatgg tctggcttca gcgagaagtt ccaacgcata
     1801 tacaaggacg tctgatgtca acgataacaa cgattaccat ggtggccagt ccacttggat
     1861 tagcactgtt tggtgcgctc tttgattggc agacaactca accacgtctg cgagacagtc
     1921 tgatttttct tgaaattcaa ttggaaaatt tacactttct ttatacattt ctggctgctt
     1981 tctttatacc cgtcaactat acttcactta tcaataagaa agaaggataa gtatggattt
     2041 tggaaatgaa acggtcttga aagcaactgg tataaccaaa aaatacggtg ctgccaaagc
     2101 attagataaa gtatcgatcg aaatcaaacg tggaatgatc tatggtttga ttggggagaa
     2161 tggagcgggt aagtctacct ttatgagaac tattatgggt ttgatctcga ttgatgaagg
     2221 ttcgatcgaa ttatttggaa cgacggattt gcaggcagca agacgacgta tgggtcaatc
     2281 gattgaaacc cctgctcttt atccagaatt aactgcaaga gataacctac gtatccaagc
     2341 agcgaacggc ggtgtgtcgg atagagaaat cgaagacctg ctgaaaatga tgcgattgga
     2401 aaatacaggg aaaaagaaag caaagaattt ctctttaggt atgcgccagc gtttagctat
     2461 tgcaaatgca ctgatcacga atccagaatt tttgattttg gatgaaccga cgaatgggat
     2521 ggatccagca gggatggcag aaatgcgaga aatcatccaa cgtttggtaa aagaacgggg
     2581 catcaccgtc ttgctttcta gccacttgct agatgaattg tcacagatcg ccactcacta
     2641 cggtattttg catgaaggac acttgatcaa agaattatcg aaagaagaat tggcacaaga
     2701 atctcgtcaa tttataaaaa ttgacacttc ggcgacggaa caagcagtaa cggttctcga
     2761 ctctcttggt tatagggatt attttgtcca atctagccgt gttatccagc tttttgaagg
     2821 aattgaccaa gtagcagcca tcaatcaagc attggtagag gcaaaagttc ctgtggatgg
     2881 tatccaccta gttgggcaaa aactggaaga ttatttctta caattaactg gaggcaatcc
     2941 acatgtttaa tctattaact gctgaaaaaa taaaagtatg gaagagccgt aaaatgtggg
     3001 tctcactagg actgatggtc gtacttccgc ttttttattc ttggaacgaa tggtatatgc
     3061 atacaaaata cggcaatgaa ttaaaccaag caacggatac agtcatcaac ggtgcaacag
     3121 ggattttaat ggtggaaaaa atggctgcat ggattcttct ggctttcgca gcatttgcgt
     3181 gcttttatat tggggaagaa tttcaaaacg gtacgattcg caatacgtta tctttaggac
     3241 ggaatcgaat gacttattat gtgtcgaaac ttctcgttac gcttttgatc acaacacttg
     3301 gcgtggtttt gattacgggg ctagccatga ttgcttacac acttgctttc ggatttggtg
     3361 aagttgaggg aatcaaaaac tatggaaatt atgttctaaa agtatttcct gtattgcttc
     3421 tgctgatatt agcgacatta tctgttccag tggctttgac attcatcact agaagtacca
     3481 gtgtcagttt gcttctttct tttctttata tcatgggaac ggccttcgtt cccggtgttt
     3541 tcgcaaaaat caaaggcttg gaatttctaa cggagtggtt tacggaaacg tggctcatgt
     3601 atacggactt tgcgcaacaa gcaacttatt cgcaagcacc gaaaatgatt ctggtcagtc
     3661 tagtaacaat cgtggtatca tcagctctag gaatgtttat tttccaaaaa tctgacatta
     3721 agtaggtgtt cctgctggaa actattttga ttatcgaaga cgatgaagct gttcattctt
     3781 tactggagga ggttcttgaa cagagataca aacttcttga tgcttattca ggtacggaag
     3841 gaaaattatt gttaagcaca tatcctgtcg atttgatcct tctagatctc atgcttccag
     3901 ggctttcagg tgaagcattg ttagcagaaa tccgacagac atcgaatgtt ccgatcatcg
     3961 ttctttcagc aaaaagcgat caaagagata aagtttcctt gttggcagca ggagcggatg
     4021 actatgtgac gaaaccattt gatatcgaag aactgttgtt acgaatcggc atccaacttc
     4081 gtcatcagac ttctgtccaa gtaaaagatc tgtcgcaacg catctattac aaggaaatct
     4141 tactggacaa agagtcgagg gatgtaaatg tgaatggtgt ggctgtccat ttgacaggaa
     4201 gagaattcga tctgctgaag ctttttttag aacatccgaa aaaagtattt tcgcgagcaa
     4261 atctttatga aacagtttgg caagaaccat attttgatag tgagaaaaca gtgaatatgc
     4321 atatttccaa tcttcgaggg aaactagcaa aggcacatgc tgtgtatatt catacggtgt
     4381 ggggagtggg gtttagattt gattaagtgg ctgttgcttc tcgttgttat ctttatggga
     4441 agttttattt tcttcctgca aagggaaatc aagagattaa ctaagaaaat cgccactctt
     4501 tctgaacgac aagaatatgg tggtcgtctt tcagtcgaat ttcgagaaaa gaatctaatg
     4561 gacctagtag atgcactgaa tacatgggtg gatgaaaatg aacaaaaagg acaagcattt
     4621 caagaaatgg aagaaaacat cagactatcg atcgtcggcc tttctcatga tctcagaact
     4681 cctttgactg ctattaacgg ttatgtacaa ttactggaac aggtagagga tacggagaaa
     4741 cgggagaagt atttaacgat catcaaacaa tctgttgcaa gattactcag tatgacggat
     4801 cagttttatg atcttgctcg aatagagacg aagcaaaaag aaatggatct ccatacgctt
     4861 tctttttcta aagaggtgga agaagtattt ttctcttttt atgaacaatt ttctgagaaa
     4921 aatatcgagg tagcgttcgc tgaacactcg ataaatacaa ctgtattagc agatccgctc
     4981 atgttgctgc gagtgctgca aaatatcata cagaatttat tgcgttatgc agatggacaa
     5041 gcaaaggtga cattttcaaa agaggattca ttcattcgat taacagtggc caatcctatc
     5101 aaaccaggag cgcaaacctc tgttgaaaaa gtcttccagc gtttttatac cgaaaatacc
     5161 agccgcacaa atacggaatc tagcggaatc gggctttacc tgtcaaaaaa attggtggaa
     5221 ggaatgggag gagagatgac cgctagatta gacgggggca tcttctccat ctccgtcaag
     5281 ttgcggaggg tttaattggc tctaatttac ctgaagtgaa tgacaaaaaa ttgtatctcg
     5341 ttttaaagac atcttctttt ttggaaggtg tttttatttt ggtgtgattg atacgaatta
     5401 ggtaacgaag acagttattt ttgtaccccc ttttcaaata gcgcaacagt gctatactaa
     5461 aactaacaaa tcaaggaacg gagagggata tgggccaaag agaatttatc gttttaatta
     5521 ttattgcagt tgttatttta ttagttgttt tagacatttt ttcacgtttg aaagtaaagg
     5581 aaacagttcg tagtaattgg ggaaaaattc cttatcaacc gagatttgat aaagaagaaa
     5641 gtttgaagga tgcgtggctc acggagaaaa aattccgttc atgggatagt gaaatcgacg
     5701 atcttacttg gtatgacttg gatatgttcg aagtatttga agggatcaac agtacctatt
     5761 ctagtgtagg ttcagaagcg ttgtatcagc gtttacgtag ctttgatttt ggagaagatt
     5821 atcagttaga aaaactaatt gctttttatc aggaaaatcc tcaactgaga gaaagaatcc
     5881 aatatcaatt cgctcgttta ggaaaaaaag atcataattt tgcaaaacaa tatctagcgg
     5941 atggaaaaag taaaaagatt ggacgcgtag gtttatttat ttttcttggc ttgcttccgc
     6001 tggtgggtgt aggtttgctt cttttagggc aagtactagg aatctatcta gcaatcggtg
     6061 gcttagtatt caatacggtc tattatctag tgaagaaaca aacactagaa acagagctga
     6121 atagcatgag ttatttggtt tcaacgattt cagccgccaa tcagttagca aaaatgacga
     6181 caccacttca aaaagagctg aaacagcaaa ctaaaccatt aagagacatc cctaaattag
     6241 gtttttcatt tcgaatgaag agcgggagtg aagcagaatt gatttttgaa tatgtcaaca
     6301 tcatgttcat gctgccattt atctcctatc atttcgttct cactaaatta gaaaagcatt
     6361 caactgaagc catcaagctg tgggaattgc tgggagaatt ggaagttgca gcagccgttt
     6421 tgaattatcg cacctatatg ccgatcactt gccgaccaga gtttactgag ggcggtgtga
     6481 cagcgaaaga tatctatcat ccattgttaa aagaagcggt agttaatcca gtcaactggc
     6541 agaagaatac attagtcacg ggttccaatg catcaggaaa atctacgtat gtcaaaagta
     6601 tagccatcag ctgtattcta gcacagacga tccaaacagc gattgcagaa cagtttaccc
     6661 tgcaacctgg acatgtgttg acttccatgg caatcgaaga tgatttattt gaaggcgaca
     6721 gttattttgt ttcagaaatc aaatcgatca aacgtttgct ggaccaagtg gcttccaaag
     6781 aacgctgcta ctgcttcgta gatgagattt taaaaggaac aaatacgatc gaacggattg
     6841 cttcttccgc ttcagtcgtt cggtggcttg cggagtatcc atctttagca tttgtcgcca
     6901 cacatgatat cgaattgaca gagattttaa agaattattg tgagaatgtc cactttgaag
     6961 aacaagtaac agaaggaaaa ggaatcagtt ttgatttcaa attaaaagaa ggaccttcaa
     7021 ggacccgaaa tgcgattgcc ttgctgaaag ttttgaatta tcctaaatcc atagttgaac
     7081 aggcccaaaa agaaagtttg ttgttcgatg aacagcgtca gtggtatccg tttgattaac
     7141 tttatcaaac gaagcatgat gcgtgggtcc aaaaagacga ttatcaaaag aagtacattg
     7201 atgccaaaaa agtggcagaa ttcaatggga acgagtctgc tgtccagatg atcttggaag
     7261 atttagcaaa agacgataca aaataaacca cgctgtcttc cttctagcag cttttatcga
     7321 aaaaacttag catcagcgac gagacgcacg ttccatggca aagttctccg taaaacaaac
     7381 agcgaaaaca gaaattgaaa ataactattt ccattttatt tatttcggtt aaaataaaag
     7441 aaaaaagctt tcgataaaag gacggaggaa agcttaacat gaataaaaaa gacaagaacc
     7501 tcagttataa ggatcttcta tatgtcatcg tagtagttgc tgtcggtact tttatgattt
     7561 taaaagttcc agagttgttt agatagttat tctatcgaag atgatcatga actagaaaac
     7621 acatctcctc tttgttagca ggtgtgtttt tgtgtggaag ccaagttgtt ttttcatctg
     7681 ctgtattcca tgatacaatt aagaatcatg tctataagga gataggaaat aaatggcaaa
     7741 tgcgcttgaa ataaataatt tgaaaaagat ctatggaagt ggggtcgaag cattgcgggg
     7801 aatcgatctt tcggtgaaag aaggagattt ctatgcgcta ttagggccaa atggagctgg
     7861 gaagtctaca acgatcggga ttattacttc tttagtcaat aaaacatctg gaaaagtgaa
     7921 tgtcttcggt tatgatctgg acaaggatct agttcgagca aagcaacaga ttggattggt
     7981 tccacaagag ttcaatttta acccttttga aacggtccag caaatcgtcg tgaatcaagc
     8041 aggctactac ggtgtctctc gcaaagaagc gatgaaacgc agcgaaaaat atttgaagca
     8101 gtccaatctt tgggaaaaga gaaatgtccg tgcacgtatg ctttccgggg gaatgaagcg
     8161 aagactgatg attgctaggg cattgatgca tgaaccacgt ttgctgatct tggatgaacc
     8221 aacagcagga gttgacatcg agttgagacg cgagatgtgg gagtttctac gagaattgaa
     8281 cgaaaatggt acaacgatca ttttgacgac gcattatcta gaagaagctg aaatgctttg
     8341 tcgcaacatc ggaatcatcc aatcgggtga actgatcgag aatacaagta tgaaagagct
     8401 tctgtcaaaa ctgcaatttg aaacatttat ctttgattta gcgccatatg ataccaaacc
     8461 tgtgattgaa ggatatgctt gtacatttga agatgagcag acaatcgctg tcgaagttga
     8521 acgaaatcaa ggggtgaacg gaatcttcga tcagcttaca agacaaggaa tcaaagttct
     8581 ttctatgagg aataagtcga atcgtttaga agaactgttc ttgaaaatca cagaagaaaa
     8641 taatcatacg gaggagaaaa atgtttaatc tttattttac tgcattaaaa agtttagcta
     8701 tcaaggaaac gaaccgctat ttgcgtatat gggtccaaac actggttccg ccagtgatca
     8761 cgacatcctt gtattttgtt attttcggaa aaatgatcgg tgggcggatc ggtgacatgg
     8821 gtggtttttc atatatggaa ttcatcgttc ctggtttgat tatgatgtct gctatcacta
     8881 gttcgtatgc caatgtttct tcgtccttct tctctcaaaa atttcagaaa aatatcgaag
     8941 aaatcttggt agcacctgtt cctacgcatg tgattatttg gggctttgtg attggtggtg
     9001 tgggtcgcag tattctcgtc ggctctctcg taacgatcat ttccttgttc tttgtaccac
     9061 ttcatgtgta ttcatggttc atggtcatca ttacattatt gatgacggca atcttgtttt
     9121 cattagcagg actgctcaac gggatttttg ctcagtctta tgatgatgta tcgatcgtgc
     9181 ctacatttgt cttgcagccg ttaacttatc taggtggcgt tttctatgcc atctctatgt
     9241 taccgccctt ttggcaagct gtttcaaaag tcaatccgat cgtttatatg atctccggtt
     9301 tccgttacgg attccttgga acgatcgatg tgccagtagc aacatcgatg atcgtacttg
     9361 tgttattcat cgttgttttg tacgccgtta cttggtattt gatcaataaa ggaagaggat
     9421 tgagaagtta gaaaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa
     9481 cgggaaaata gttcctcata ttttgttgtt ttttgagcga ataccgaggg tcagctgatt
     9541 gaacaccgtt tagtggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
     9601 caaacaaaaa tagctcctcc tatttttcgt ttggttggac ttattaccgc agatgcaagc
     9661 ttttgaacac catttattcc ggaaaatgga ctgtgataag atttttgtca cagtcttttt
     9721 tttgctcaat cagaaacatc ttttaagctg ttcactttgc ttcttttttt gtttcctagt
     9781 ataatgacaa tgtttttgag aaagattgcg acttcactgc ttgatagaat ggagagtaac
     9841 aaataaatga ctactaattt ttggaaagag ctgccaaagc ctttttttgt tttagcacca
     9901 atggaagatg taacagatgt tgtatttcgc catgtcgtaa agcatgcagc agcaccggat
     9961 gtcttcttta ctgagtttac aaactcagac agtttctgtc atccagatgg aaaagacagt
    10021 gtacgaggaa gattaacatt tacagaagat gaacagccga tggttgccca tatttgggga
    10081 gacaagccag aattttttag agaaatgagc attgctatgg cagaaatggg cttccaagga
    10141 atcgatatca acatgggctg cccagtccct aatgtagcag aacgtggaaa aggcagtggc
    10201 ttgatccttc gtccagaagt agcggcacaa ttgattgaag cagctaaagc tggcggtttg
    10261 cctgtcagcg tcaagacgcg tatcggctat acggaaatgt ctgagatgga agaatggatc
    10321 agtcacctac ttcatcaaga tatagccaat ctttctgtcc atttgcgtac gcgtaaagag
    10381 atgagtaaag tagatgcaca ttgggaagtc attcctaaaa tcattgcttt acgtgaccaa
    10441 atcgctccac aaacactaat cacgatcaat ggagatatcc ccgatcgcca gacaggagaa
    10501 gaattggccg agaaatatgg cgttgatggc atcatgattg gccgagggat tttcaagaat
    10561 ccttatgcat ttgaaaaaga cccgagggaa catacagaaa aagaactgat cggactactt
    10621 cgtctgcaac tagatctgca agatcattat tcagaaatca tcccgcgttc catcacagga
    10681 ctacatcgtt tctttaaaat ctatatcaaa ggatttccag gagcaaatga cttgcgagtt
    10741 cagttgatga atacgaaatc tactgatgaa gtacgagaga tcttagagac ctttgaaaaa
    10801 gaacatccaa cgcttttcag tgaacaatga tttcttgctt gaacaccgtg aattagaggt
    10861 cgtgaaaaag ctgtcctgta tcaagtaata agaacagcca aacaaaaata gctcttcata
    10921 ttttgtcgtt ttttgagcta ataccgaggg tcagttgatt gaacaccgtt tatatcagag
    10981 gttgtgagcc tgccgtttaa ctctgagtca caaggagcaa tttcaaaaaa cagcttctca
    11041 tgtttgatga atattttgac ttgtgaccga agagttggta ggagaacacc gtttataaga
    11101 ggttgtgaca aaagtcttgt cgcaacctct tttttaacca aaaaagtgca aatagtttac
    11161 tttaagtaag agaataatta tgatgaataa aaaaggtgga acaaatagca tactatatat
    11221 attgaaatga acactgtatg gatgctccaa cttgatgaag ctaaggagga attcgtatgt
    11281 cagaaaagga attaatgaag gtagtcggtt tttatgaagg gttgccgatc gatgatccaa
    11341 aaagctttat tgatgaaaaa gaacagatac ctgtacccag ttcacgggat cttctggtaa
    11401 aagtcaacgc agtatctgtt aatcctgtcg atacgaaact tcgccaagat aacgggataa
    11461 gaaatgcttt acgtatctta ggttttgatg gagtcgggaa agttgttgct gtaggtgacg
    11521 aagtgcaaaa attttctgtc ggcgatcgcg ttttttacgc aggtacaaca agagcaggaa
    11581 gcaatcaaga ataccaacta gttgacgaac gtattgtcgc tcttgcacca aaaaatcttt
    11641 cagatgaaga agctgcagcc ttgccgttga cctcattgac cgcttatgaa ttgttatttg
    11701 aaaaatttgg tctaactcca gaagaaaatg ccaatcgcgg gaaaaaaatc ttagtgatca
    11761 acggatccgg gggcgtcggt tcgattttga atcaactagc gcattgggct ggcctagaag
    11821 tctacgcgac tgcaagtccg aagaattttg aatggctgaa aaaaacaggt gtagactatc
    11881 caatcgatta tcatcacgac ttaagtaaaa gttttcgtga attaggaatc gatcaagtag
    11941 agtatgtcgc tgtattattc gatattaccc gctactttga tcaaatcaag caccttgtcc
    12001 gaccatttgg acatgtggga acgatcgtag ggatcaaaga gccgttagat ataggtgttt
    12061 ggaaaaacca atctatcagc ttcgactggg agtatatgtt cgctaaaaca gactataact
    12121 atgaaatcga aacgcaagga gaagctttag cgcacattgc tgctttagca aatgaaggga
    12181 ttatccgcag tacattgagc aaggtctatt cagatgggat gaatgcgaag aacttgaaac
    12241 aagcaaccaa agacgtagaa acaggacata tgttaggaaa agtcgttgtt agtggtccgt
    12301 tcaacggata agcaagaata cgccgatttt tttcttattt gactttgata aaaacaagag
    12361 cgcatgacag taatttgcca taagctcttg tttttttatt tataataagc gaatcaacga
    12421 aagggaaaga attcctgcca agacgatcac caataagctt tttgaaagaa tagcagctaa
    12481 aagtgtagga actgaagcca aagcattttc gagattgatc tgcggcagat gtccgatatt
    12541 ttgggtaaat agactgctga accataaagc agacataatg acgatcggga caaaacttaa
    12601 atactcaagc aacggttgcg gtaaatcgaa ttttttcagt aagacaaatg gtaggaccct
    12661 agaaagccaa gttgctaaag tacaacctaa aatagtcagc aatgtaaact caaaagaagg
    12721 catgtttgat ccacaccccc aatccgcacc caatcagtgt tacaactaca atcactaagt
    12781 tgcttgggat aaaaatcagt ccgacatata ccagaatcaa agtgagacca atcaggatca
    12841 actgtaatcg tttagaggtg tttctatcag aaatgacttg aagataaagt aacccgataa
    12901 acatagcgac gatggcgaaa tccaaaccaa actttttcgg atcagtaata aaattcccta
    12961 aaagtgcgcc aacaagagaa gaacccaccc acgtcaaata agaaatccaa ttagctgtat
    13021 tcatccaacg aaagtttaac ttttgtccag tatagttcaa tttattcatt cccagtgcga
    13081 aactttcatc tgtcagcaat gtgccaatca gcagattttg aagcagccga tttttcttga
    13141 aataaggagc aatcgtcata ctcatcagaa tcattcggga attgactaga aaggtcgaga
    13201 aaacgatgga aagcaatggg ctgtgactag caagcatgct gactgtgata aattgggcag
    13261 aaccagcata gaccagcagg gacatcaacg tgacgactag tggatgaaat ccggcagctt
    13321 tcccaacgat accaaatgca agtccaatac cgatataacc gaaaacggta ggtaacgtgt
    13381 ctttgatcgc agtttttata tctaactttt catccaataa caaaactcct ttagcacgac
    13441 ataaattttc ataattgtcg ttaaacttgt gaatattcta aatttttaat gagcatttgt
    13501 caatggtggg attgaaacgt aaagaactag cgggtcgcag atttacacgt attgtttcgg
    13561 tgggaggagg cgcgaaaaat cttgcatggc tacaaatcca agctgatatt ttcgatgcaa
    13621 cggtctattg tttaagtgtg gaggaaggac ctgcattagg cgcaacaatg attgctgcac
    13681 tagggttagg gtggttcgac acacctgaaa gttgttgtca gaattttatc caatatacag
    13741 atgcagtgga acctctctta caaaatgtag aaaagtatca taaaatctat caacaatgcc
    13801 ggaaaatcta tccagcaacg aaggaaattt gtcatgactt ataaaacaaa acgcgtacct
    13861 aatagtcaaa tgactaatat tgggtacgcg ttaagtcttc tttacttcat cctttgcatg
    13921 attcgtgttt ttaaagcaag gtctgctgta tttcttgtgg atttaggatg gttgttatcg
    13981 tttacttgct atttttcatt gaaatcgtct ttctttaccg tttctttagt tttttatcta
    14041 tttttttctt ttggttagaa aattcttttt cccgaaagtc ttctttcagg atttttatag
    14101 agtagcgttt tgaataagag gcgtcagtat gatcgacttg gcagacgaac caagagaaca
    14161 tttgcctttt ttctgcatga ggtgcttctg ctaataattc tttccataaa taataacagt
    14221 cctctatcag aagaagggtt cgttcatcct caggctccca atagaatgtt tcgagagtag
    14281 caatcacttc attgatcaat tcgaatgcgg gaagataggc attttgctga ataagcgatt
    14341 caactgcttc ttggatgaac tttcgcatct ccatgatgaa cttcgctgtt ttcctgtttt
    14401 tgtttttctt gataatatga tcgtatttat ggatgatagt tgttaattta tctgaataat
    14461 ttattgcatg aaatggcatc ttaactttga agcgttcgat aaagtgcgga tgttctataa
    14521 gaatctctgt taaaagctcc cgtacaagag aggaactagc ggaggaaaca agggacgaga
    14581 gttcggaaag tgagtagttg gattttttta ttggacgttc ttcgtaagcg aataagacag
    14641 cagccatgtg tttgcatttt tttccttcta tggcatatag acaatcacaa gtcatgttgg
    14701 tcttttcatc ccaagtgatc actaccttat aatcttccgt gccagaaact gttgcggaca
    14761 agtacttgct tgtatagttc aaatgacgga caaaaccgtg cagatgatag ctgtaaccgc
    14821 gttccaaaac gttttcagga aaatactcaa gccaattatt catctagttc tcctttcatg
    14881 aaacacttat ttatatttag tataaagaaa cgtttaagaa aaaagtagct gattttacat
    14941 atttgataat cacttttgct cgaattgtca aaaattcatt ctccttttct tttcttagag
    15001 aatgtgagaa aaagtaaaag aatagcgtgt tttaaagatg gaactttttt tgttttttat
    15061 ttatctgaca aaaatgaagt gattttgtta gaaataaata attgttccaa ttgataaaag
    15121 aggtatgatg tatcgcaaag a
//
LOCUS       DARPZJ010000060        14548 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.063, whole genome shotgun sequence.
ACCESSION   DARPZJ010000060 DARPZJ010000000
VERSION     DARPZJ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.063"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            4..816
                     /locus_tag="SLE23_002248"
     CDS             4..816
                     /locus_tag="SLE23_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEI8469125.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="SLE23_002249"
     CDS             813..1613
                     /locus_tag="SLE23_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEI8469126.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="SLE23_002250"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="SLE23_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEI8469127.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="SLE23_002251"
     CDS             3110..4819
                     /locus_tag="SLE23_002251"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEI8469128.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="SLE23_002252"
     CDS             5031..9389
                     /locus_tag="SLE23_002252"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEI8469129.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="SLE23_002253"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="SLE23_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEI8469130.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="SLE23_002254"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="SLE23_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEI8469131.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="SLE23_002255"
     CDS             11227..11520
                     /locus_tag="SLE23_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEI8469132.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="SLE23_002256"
     CDS             11517..11828
                     /locus_tag="SLE23_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEI8469133.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="SLE23_002257"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="SLE23_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEI8469134.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="SLE23_002258"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="SLE23_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEI8469135.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4959 a         2583 c         3238 g         3768 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaaccaaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaa
//
LOCUS       DARPZJ010000061        13778 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.064, whole genome shotgun sequence.
ACCESSION   DARPZJ010000061 DARPZJ010000000
VERSION     DARPZJ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.064"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(45..1364)
                     /locus_tag="SLE23_002259"
     CDS             complement(45..1364)
                     /locus_tag="SLE23_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8469136.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="SLE23_002260"
     CDS             complement(1361..2014)
                     /locus_tag="SLE23_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8469137.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="SLE23_002261"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="SLE23_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="SLE23_002262"
     CDS             complement(2724..3440)
                     /locus_tag="SLE23_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HEI8469138.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3490..3699)
                     /locus_tag="SLE23_002263"
     CDS             complement(3490..3699)
                     /locus_tag="SLE23_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469139.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            3976..5249
                     /locus_tag="SLE23_002264"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="SLE23_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="SLE23_002265"
     CDS             complement(5356..6387)
                     /locus_tag="SLE23_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469140.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="SLE23_002266"
     CDS             complement(6394..7224)
                     /locus_tag="SLE23_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469141.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="SLE23_002267"
     CDS             complement(7221..8036)
                     /locus_tag="SLE23_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8469142.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="SLE23_002268"
     CDS             complement(8033..8857)
                     /locus_tag="SLE23_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HEI8469143.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="SLE23_002269"
     CDS             complement(8847..9947)
                     /locus_tag="SLE23_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEI8469144.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCVSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="SLE23_002270"
     CDS             10125..10910
                     /locus_tag="SLE23_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HEI8469145.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="SLE23_002271"
     CDS             10943..11326
                     /locus_tag="SLE23_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEI8469146.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="SLE23_002272"
     CDS             11402..11533
                     /locus_tag="SLE23_002272"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8469147.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="SLE23_002273"
     CDS             11502..11738
                     /locus_tag="SLE23_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8469148.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="SLE23_002274"
     CDS             complement(11816..12787)
                     /locus_tag="SLE23_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEI8469149.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            13439..>13778
                     /locus_tag="SLE23_002275"
     CDS             13439..>13778
                     /locus_tag="SLE23_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8469150.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVSQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVR"
BASE COUNT         4179 a         2995 c         2387 g         4217 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atgtcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagacgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttatccag actgtagaca aagtccattt tatggatgat
    13381 gtctacagtc ttttctttta taatagattt atgaaaacga atgcaaggag tgatagctat
    13441 gatgtctaaa aacaatacga atggtagaaa tcaatttgcg atgcttacga ttgatgatct
    13501 agtttctcaa gatcatctcg ttcgaaagat tgatgccgcg cttgattttg aatttattta
    13561 tccaatcgtc gaagccactt actccgattt aggtcgccca agtatcgatc cagtgattct
    13621 gatcaaattg gtgtttattc agtatttatt cggtatccgt tccatgcgac aaaccattaa
    13681 ggaagtcgat accaatgtcg cttaccgctg gtttttaggc tactccttcg aggagaaaat
    13741 cccccatttc tcaacttttg gaaagaatta tgttcgcc
//
LOCUS       DARPZJ010000062        13487 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.065, whole genome shotgun sequence.
ACCESSION   DARPZJ010000062 DARPZJ010000000
VERSION     DARPZJ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.065"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(163..387)
                     /locus_tag="SLE23_002276"
     CDS             complement(163..387)
                     /locus_tag="SLE23_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HEI8469151.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(585..2165)
                     /locus_tag="SLE23_002277"
     CDS             complement(585..2165)
                     /locus_tag="SLE23_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEI8469152.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2566..3942)
                     /locus_tag="SLE23_002278"
     CDS             complement(2566..3942)
                     /locus_tag="SLE23_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEI8469153.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4070..5188)
                     /locus_tag="SLE23_002279"
     CDS             complement(4070..5188)
                     /locus_tag="SLE23_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8469154.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5330..5764
                     /locus_tag="SLE23_002280"
     CDS             5330..5764
                     /locus_tag="SLE23_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8469155.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5842..6375)
                     /locus_tag="SLE23_002281"
     CDS             complement(5842..6375)
                     /locus_tag="SLE23_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEI8469156.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6469..7647)
                     /gene="mutY"
                     /locus_tag="SLE23_002282"
     CDS             complement(6469..7647)
                     /gene="mutY"
                     /locus_tag="SLE23_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEI8469157.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7640..8437)
                     /gene="recX"
                     /locus_tag="SLE23_002283"
     CDS             complement(7640..8437)
                     /gene="recX"
                     /locus_tag="SLE23_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEI8469158.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8544..9926
                     /gene="rlmD"
                     /locus_tag="SLE23_002284"
     CDS             8544..9926
                     /gene="rlmD"
                     /locus_tag="SLE23_002284"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEI8469159.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10100..10678)
                     /locus_tag="SLE23_002285"
     CDS             complement(10100..10678)
                     /locus_tag="SLE23_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HEI8469160.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11000..11470
                     /locus_tag="SLE23_002286"
     CDS             11000..11470
                     /locus_tag="SLE23_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HEI8469161.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11578..12804)
                     /locus_tag="SLE23_002287"
     CDS             complement(11578..12804)
                     /locus_tag="SLE23_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEI8469162.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3959 a         2719 c         2248 g         4561 t
ORIGIN      
        1 aaagaacact tttgtctcac gctctaaaca cgtataaacg gcgaaagcag aagcaactcc
       61 ttcggaaata agctgaaatt cacgaaaatt gcttttcaaa tttttgtgaa ttccagctta
      121 tttcttggag ttaaacgctt ctgtctcagc ctctttttct ttctagcttt ttgatttttc
      181 tcttttcttt tgtacttttc tcttttcatt ttcagttcta cgcgtgtctt tatttttaac
      241 tttttcctct ttatggatga ttgatcgtac tttttgtgca atttgctcgt ttttgtccca
      301 gtcttttaca tctaataatc gacataatcg taacatctct tcttttttct gtttttttct
      361 ttcacgtctt tgccattctg tttccatgtg tcacactctc ctttctttaa tcatatgtac
      421 gcaaaataat ttttatattt ttttgattag acatttctat gattttaata tagtaaaaag
      481 agccgtcacg gaaaatccgt cacggctcta aacaaaatat gagaggctgt ttttgtttgg
      541 ctattcttat tacttgatgc agggcagctt gtgtcaagac ttctttacat caaacttttt
      601 aattttacat tgggatattt atccgcaaac cagcgttctg caaattggtt ctcgaataag
      661 aacaacggtt ggtcgaaacg gtcacgagcc aagatattgc gacttgaact catcttctca
      721 tccaaatctt ctggatcgat ccagcgagcg attttgtgtc ccattggaga catgattact
      781 tcggcgttat actcatttaa catacgatat tggaatactt cgaattgtag ctgaccaaca
      841 gctccaatga tatattcttc cgttagatat gttttataaa gctgaatcgc tccttcttga
      901 actaattgat agattccttt gtggaaggat ttttgtttca tgacattttt tgcagtcact
      961 ttcataaaca gctctggagt aaatgaaggg agttcttcat aagcaacttt tagttttcct
     1021 tcgaacaatg tatccccaat ctgataattg cctgtatcat atacaccgat gatatcgcct
     1081 gctactgctt tttcgacgtt ttctctcgaa tctgccataa attgtgtgac attgcttaat
     1141 ttcagttttt tatttgtacg ttccaaccag acatccattc ctcgttcgaa tgttccagaa
     1201 cagattcgga caaaagcgat tcggtcacga tgggctggat tcatatttgc ttggatcttg
     1261 aatacgaaac ctgaaaattc ttcctcataa ggacttacca tctgatcatc ttgtgttttg
     1321 tgtccataag gagctggtgc caattcaacg aaagtctcta aaaaagtctg tacaccgaag
     1381 ttagtcaatg cagaaccaaa aaatactggt gtctgatcgc cacgagcaat tttttcttga
     1441 ttaaatgcat ctccagcctc tttgattagt tctacttctt ctaagacttg ttcatataag
     1501 gaattttcag ttagaggatg attttcggga agcagtccat cttcatccaa ttctactaat
     1561 cgttcatcct gataattttc cggacgataa aactctacac gattatggta gatatcataa
     1621 agaccttcta gccctttacc cataccgatt ggccaattca tcggataaga ttcgatatct
     1681 aatagctctt ctaattcttc taacaattcc aatggttcac gaccatcacg atctagtttg
     1741 ttgataaaag taaatatcgg gatgccacgt ttttttacaa cttggaataa tttctttgtc
     1801 tgtgcttcga tcccttttgc actatcgatt accatgaccg cactatccac ggccatcaaa
     1861 gtacgataag tatcttcaga aaaatcttca tgtcctggtg tatccaagat atttactcgt
     1921 ttcccttgat aatcaaactg cataacagaa ctagtaacag aaatcccacg ttgtttctcg
     1981 atttccatcc agtctgattt ggcaaaatta cctgtttttt tgccttttac ggtcccggct
     2041 tgacggatag ccccaccaaa caatagtaat tgttctgtaa tcgttgtttt cccagcatcc
     2101 ggatgggaaa tgatcgcaaa agttctgcga ttgtccactt gttgctttaa ttttggatta
     2161 ttcataacct aactccattt cttccattca attatttata ttttctctag gcacagattg
     2221 tccgatctct taaagaaaga caatttcata tagggctgtg acaaaagccg tgtagcagtc
     2281 tctttttccg agtaaacggc gttctagaga cagcctatca gcaataagcc cacccaagcc
     2341 aaaaatacga aaagctgttt ttgcttggct gctcttatta cttaatgcag gatagctttt
     2401 tcacaacctt tgtcaactac tacaactgaa tcagtatagc atggattcag cgaatgaaaa
     2461 agccaccaaa ccataagagt caaatatttt tttgtcagct gactaaaaga aaagacgtgt
     2521 tgcttgttta ttcaagcaac acgtctttca taaccaagtt tccaattatc ttcttggctc
     2581 gtcatcttcg aattcttttc tgaagtatct tcgttcttct tcaggttccg cttctgtttc
     2641 ttccggatca tgaaaaatga cacggatttt aaggattcga gaaccttcca tttcttcaga
     2701 aaccagcgta atattatcga catcaaacga taacttttcg ccttcatccg gaatcatgcc
     2761 taatgctgta atcaaataac cagccatcgt atctacatca ctcatatgca gatcactgtc
     2821 aaaagcttca ttgaactcat caatcagcat acgtccttgg atgatatatt cgtgttcatc
     2881 gattttttca taaagattct caacttcatc tgattcatca tcgatttctc cgacgatttc
     2941 ttctaaaagg tcttctagtg ttgctaaccc aacgacgccg ccatattcat ctaataaaat
     3001 agccatctga ttctgcgtct ttttcatttc atataacaga tcatcaataa agaccgtttc
     3061 aggaacgaat aaaggctcct gcatgatttt cttgatatct aaattatcaa agccgaattt
     3121 atgggcagct tttagtaaat tctttgtatg aaggattccg actactttat ctttgtcttc
     3181 gttataaaca gggattcttg aatagttttc ggataaaact tcattcacat tttcttccac
     3241 agtgtcgttg atatcaatca taaatgcatc cgttcgtggg accatgactt ctcgggcaac
     3301 tttcgtatca agagaaaaaa ccccttggag catttctaat tcttcattat tcaatacgcc
     3361 ttcgttttca agcatataac gcatttcatc tctggtcatt tttgaatctt catcatcaaa
     3421 agtcatcggc gtgatacgcg ccaataaact tgtggaagca gaaagcagcc agacgaaggg
     3481 cttagctact acaccaatca agcgtatcag ccctgaagtg aactttgcga cttcttctga
     3541 tttatttaaa gcaatacgtt tagggtacaa ttctccaaaa acaatcgata cataggtcaa
     3601 aatagccagc acaatgatat ttgcaatatt ttttgccgct gtgccgccac ctaataccgg
     3661 agctaaccgt tccgataaag tattagctag tgaagcacca gacaaaatgt tgaccaaagt
     3721 gattcctact tggattgtcg ataggaaatt atttggattc tgcaatattt ttaaaagctt
     3781 ttgagatttc acatctcctt catcagcttt ttgctcgatt cgattcttat tgatcgaaac
     3841 aacagcaatt tcggaagctg ctaaaaaagc attgatcaat gtcaaaacga tcaataataa
     3901 aatctgcgct aacagcgact gactctcagg gtcagcattc ataatcgcat tctctcctta
     3961 taaaattaat ttttagttta cgatagaaaa aaacgtggca ctatagccac gttaaaatgg
     4021 tatcacaaag caattttctt tgcaataaaa acaagtgtac taaaactacc tacgaggtcg
     4081 tagcaatttt cttcttgttt tcattttgct tgtcttcttt gacgattttg attatatagg
     4141 aaatgatcgt cttgcagatt gcgtaaaaag gaacacctaa gaagatacca agcaatccgg
     4201 caatatttcc agctactaga agaacgataa tgatcgttaa tggatggatt ttcagtgatt
     4261 tcccaattac attaggataa atgatattcc catccaactg ttggacgatt agcacaacca
     4321 cacaacaaag taatgctttt accggatcat tgaagactgt tactagaaat gcaggtgcta
     4381 gtcctagata aggtcctaaa tatggaatta ggtttgtcaa tcccgcaatg accccaaata
     4441 agaaagcata atccacacca attaccatat atcctaaaaa tgtgaaggta ccaacgaata
     4501 aacattcgat tgcttgtccg ctaatgtaat tagccaatgt tttattcagt tgccccaata
     4561 actccacaat ttggtttctt cttttttctg ggaaaaactg ttggatgttt ggcactagtt
     4621 tttctccgtc tttcaacata tagaacaaga tgaatggtgc tgtaatgatt actacggttg
     4681 ccgaagcgat cgttccaacg atcgaaccta aactattgga tactccacta aggaattgct
     4741 gaatgattgt cccgtaagaa atgtctaatt gctcaaaata tttattgata tctacttcct
     4801 tgaacaaagg caattcggct acctctttta accagctttc tacctgtttg atgaaatcag
     4861 gcatattaga tgccaatgag gaaatttgct gtactagact tgggatgaca ctaagtaaaa
     4921 tccaaataat tgctgcaact aaaaggagca gcacaattgc gacagcccat attcttttga
     4981 tttttgcttt catcaacagc ttgacaatag gattcaataa atagtaaaga aagcctgcaa
     5041 tcagtacagg tgcaaataac gtggaaaaaa atgtcccgat cggttcgaaa ataaagttta
     5101 tttctgatga aatcatgatc aatgcagcta tgatcaataa ttcaagcgac caaaacatta
     5161 gtttagactg tctaagtttt tcaaacaata gatttcctcc tttctttctt actagtatat
     5221 attatattcg ttaaaaattc ttttattctt tttttatttt tgaaaacttg ccatactttt
     5281 tatttgtttt attttccagt atactatacg aaaggaaggt ggctagacca tgaaagttgt
     5341 acaaacaaaa gatacaatga gcaatattta cttagatgct gtacggatca ggcatcaagt
     5401 ttttgtagtc gaacagggtg tgcctttgtc tcgagaaata gacaaagatg aagcccattg
     5461 tatccacttc gtcctgtact cagataaaaa agaaccgcaa ggaactgtac gtcttttgcc
     5521 tttagaaaac ggaaaaatga aattacagcg gatggcgatt ctttctgaat acagacacca
     5581 agggttagga aaaatattga ttgaagaagc agaaaacttt gctaagaatc aaggctataa
     5641 tacgatttta ttaggggcac agtccacagc tgaaactttt tacgaaaaac taggatatac
     5701 agcttacggc gatccttttg aagatgctgg catgcctcat atttatatga aaaagacttt
     5761 ataaaaattt atttcgaaaa aagcaaaaaa cagcaagctt ttgagaaaaa tctctcactg
     5821 gcttactgtt cttttttgtg tttacttacg cgacaattgc ttgtaacggt tataccaaat
     5881 atcaatatag ccttccgaga acgggccatc tccattattg atccagtcaa ccagaatctt
     5941 cacattttct tttaggatga agtcaatatc gttcgggtaa ttcatcattt tgctgtgcat
     6001 ctcatattca tcgacatcca atagtcgttt ctcgccgtca ggaaatacct tgatatccaa
     6061 gtcatagtcg atatatttca aggcctcatc gtccagcaaa aaaggtgaag ctagattaca
     6121 ataataggaa accccctttt ctctgatcat tgctattaca ttgaaccagt attttttatg
     6181 aaaataaaca atcgctggtt cgcgcgttac ccatcggcgt ccatcagatt cagtgactaa
     6241 tgtgtgatca ttcacgccga tcatagagtg ttcgcttgtt tttaatacca tggtatctcg
     6301 ccacgttcga tgcaatttgc cgtcgtgctt gtaactttgg atcgtcacaa actctccttc
     6361 ttttggaact cccatagcaa cccttcctta agcagcattt tgtgctttgt gtttgggtgt
     6421 tcattacacc gacatcataa ttattatatc aataaaaatg agctttgcct agaaaggatt
     6481 cctattgttt cgatttttct ctaactgatc taccagtttc atttggacct taggaaaaac
     6541 gaccgaatca aatgcatcag gcttcaacca cttcgaagtt ttgttctcgg taaattcttg
     6601 ttctgctccc tcggttgccc gtccgtaaaa aaggagaaca tgccatttca gatgactaaa
     6661 aatatgagta acttctccta aatgtcgtgt ctgccaaaca aagagttcct gcttttcaaa
     6721 tgggagattt tgctcttctt ctgctactag gtcatcaaac agatcgattt ctggctttgt
     6781 ttcccattct tttttcaatc gctcatactc ctcttgtgtc acttccatca ttggaaatgt
     6841 ccacatattc gccagcaatt tttggctatc tctttcttca aaataatacg ctccagaatg
     6901 attttgaaga gctgcactga tataataaac gtcttttggc tttgcttttt ttgtttttac
     6961 aggaaaactc gtttggattc ctcgtttgtt agctaaacaa aaggcttgga tcggacaagt
     7021 ctcacacttt ggagaagttg gtgtacagat agctgaacct agatccatca ttgcttggtt
     7081 gaattcacct ggatgctttt catcaatgat tttccgcatc gcttcatcaa agattttcct
     7141 gctagaagct tttgcgatgt ctgcttcaat gcaaaacaat ctgctgacta ctcgcatcac
     7201 gttgccgtca actgcaggtt ctggaagtcc aaatgcgata cttgcaatcg cgcctgtcgt
     7261 atatggtcct attcccttca atgagctaat ttcttcaggc gtttgcggca tttccccatc
     7321 aaattctgac atgatctgtt tagcagcagc ttggatgttc cgggctcttg agtaataacc
     7381 aaggccctcc catgctttta aaagcttttc ttctggagca tttgctagct cttcaattgt
     7441 aggaaaccat tccatgaaac gataaaaata atcgatcact gtgtctactc tggtttgctg
     7501 aagcatgatc tcagagatcc agatacgata aggatcacga ttatagcgcc aaggcaggtt
     7561 tcttttttct tgttcatacc attgaatgaa ctgatcttga aattcttttg tttctttatc
     7621 tgtccatttt tcccattctt tattcacttt cctcttcctt ttccgtaatg aatcgctgga
     7681 tcatatccaa atcaaatcct ttttgatata agctttgctt tacttttaga tttctttttt
     7741 taggttcaaa ccttaaattt cttcgccata gtttatctcc ttgtttgact aaataatcat
     7801 attctatttc ttgatctgct tcttgcggaa gatcagctat cgcttgttgg atcacttctt
     7861 gagaaaagcc tttcgtcatc aatgtttgtt ggatttttct caataattct ttttggcttt
     7921 ttccgtgatt ttttccaaac gctttttcgg ctgtctgatg tgcattttga acttggtctt
     7981 caaatgtata ttggctgagc gcttgttcaa tgatttcagg tttcaaacct ttttgctgca
     8041 tctgctgcgc taatttcttt ggtcctttgt cacttaagcg catattcgtg cgcacataac
     8101 tttccccata gaccaaatca tcgacaaggt ccaattcttt taagcgggct acgattttat
     8161 ttcgatcttc ttgaaggatt tccttttctt ttaagtatgt tcggatttct ttttccgatc
     8221 gcaactgata acttaagtaa ttcattgcta ggtgaaaacc gaaatcagct ccgctactct
     8281 tcttgatctc ttggatagtt tcttcgtcta attcccgtcc ttttaataat cgatagcgta
     8341 ctaatacatc ttcagatact tgtaaagctt ctccttcaga taaatctacg cgatagaaag
     8401 ggcctttgcc tttactgatt ctcgtaacgg ttaacataaa catcctcctc gaacatatat
     8461 tctctatcat accacagaaa atccccgtaa tcaggtatta tatgttagaa taaaccacag
     8521 aaaaaagaaa aagggagata cttatggcag aaacaattgt caaaactgga caaacggttc
     8581 ctttgaaaat caagcgttta ggcataaatg gtgaaggaat cggttatttc aaacggttga
     8641 tcatatttgt tccatatgca ctaccaaaag aagaagtact agtgaaaatc acgaaagcaa
     8701 ctcctcgcta tgcagaagga gaattaataa aagtcaaaaa aacaagcaaa gatcgcgtag
     8761 tggcaccatg tcctgtttac tatgaatgcg gtggctgtca attacaacac ttagcttatc
     8821 aagctcaatt ggattttaaa aaggatctgc ttttgcaagc attggaaaaa ttcaaaccag
     8881 caggctttcg atcttatcaa cttttgccga cgatcgggat ggatgagcct tggcattata
     8941 gaaacaaagc acaatttcag ttacgaaaaa ataagcagac tcaaaaaatt gaagctggtt
     9001 tatacgaagc aaactctcat cagttagtcc ctataacaga ctgcttggtt caagaacctc
     9061 gaacacaaaa agtaatgaat actgttgttc aactattgaa taaatttgat gcacccatct
     9121 atgatgaacg gacaaacagt ggaatcttcc gcacaatcat ggttagaatc ggtgttaaaa
     9181 ctggggagtt acaagttgtt tttattactc gcagtaaaaa attcccgcaa aaaaacgcaa
     9241 tgatccgtga gatcaatgaa cgactgcccg aagttgtttc aatcatgcaa aatgtccagg
     9301 cacaaaaaac gtctctcgtg atgggggatg aaacgatcca cttatgggga aaagaagcca
     9361 ttgaagaaca aatcaatgaa gtgactttcg atctttctcc tcgtgccttc tttcaactca
     9421 atcctcagca gaccgaattg ctttatggcg aaggaatcaa agcattagat gtccagccta
     9481 atgaaacgat cgtggatgct tattgcggag ttgggacgat cggcttaagt gtagcaaaac
     9541 aagccaaaga agtacgggga atggataccg ttcctcaagc aatcgctgat gcaaaaaaaa
     9601 atgcggaaag attaggatat cacaacactc gatatgaagt cgggacagca gagcaagttc
     9661 tgcctaaatg gttgaatgaa ggttttcagc ctgatggtat catcgtagat ccaccacgta
     9721 cgggtttgga taacgcattg atccaatcat tattgaaata ccctccaaaa aaacttgttt
     9781 atatctcctg taatgtttct acacttgcca gagatctggt taatttaagt aaaaagttca
     9841 agattgaata tttacagtcc gtcgacatgt ttcctcagac tgcacgttgt gaagttgtcg
     9901 tgaagatgac gagactcgct gactaaatga aagaggttgt gaaaaagtct gccctgtatc
     9961 aagtaataag aacagccaaa caaaaatagc tcttcatgtt ttatgaatac tgtacttgtg
    10021 accgaagagt taacaggagg acactattta tttaaaaaaa gggttgtgac atagtttttg
    10081 tcacagccct ttttgattat tattggatat tcacgtctat cacttgataa aatgcatttg
    10141 tcgtatcgct gatattccat actgctaaaa tcacattata tccttttcga tcctgcggaa
    10201 gtgtgatcgt ttggttgact gtttttggtg gaacagttgc tttgtcgtct atttttgtga
    10261 tcaattcaaa atcactaaat ttcaaaggtt gattaggatt ccaagttggt ttggtaatgt
    10321 agtaatccca agtacttgtc cgatgttgtg ctgttaaatt ccaagtaata tttaatgttc
    10381 ctggattaac catgttttta tgccatctgt tagatgtctg ttcatctaaa ggctcaaagc
    10441 cgctgactcc tgcactagca atttttccat caatgaatgt atttttggta gcttcgatac
    10501 tttgcggttc ccattgtgct cttccgacat tttgatttaa gtttcctgct gctgatgttc
    10561 ctaggtatgc acggcttcct ggagaagtaa tataaccatg cgcaaaacct ggaatgctaa
    10621 aaccgaacaa ccctaaacta actaacccaa taaacaataa cgtactaatc tttttcatgt
    10681 agaaacctcc ttcatttgat aaccacattg taaacgcttt attgtattaa cacaaacatt
    10741 atgcttttat aattttatgt tgaagtaaaa aaggtgaaaa aagtaagatg cagattataa
    10801 cagaagtaga cgagaaaagt acaaatagaa aacatgagaa tcaaatcata tgatcttttt
    10861 caaaaacatc attcatataa acaaatgttc aactttttaa taacaacaat tatcaatttt
    10921 tttcttactt cacaaactaa atacaggtct tgctgtgagc cttcatggta aactaatatt
    10981 atagaaagga gttagtaaaa tgaagatgat aaaagatatt cgtttttggg tttgtgttat
    11041 aggaattgtc atattaggct ttttatcagg gttgcttagc ggaaatcccg gaaaatatta
    11101 ctattctttg caacttccac catttgcacc acctagctgg atatttgggc cgatgtggac
    11161 cttactgtat atattgatgg gtatttctct ttatttgtta cttaatcaca acaacaaaaa
    11221 acagcgaaac aatcttgtcg gtctttttgt gattcagttc atttttaatt ttatatggtc
    11281 tgctctattt tttaatttaa gaaatatttt cattgcagca atcgatatta cacttttagt
    11341 tattttcttg tcagtgctta tgtatcagtt gtggctgcat catcgcctgg caatgtggct
    11401 catgattcct tattatttat gggtactatt cgcaactcta ttgaattatt caatttattt
    11461 tttaaactaa gcgctaaaaa gagacgtcct gtaatttaac acatagaaaa agtgccacct
    11521 aagttagatt ttttgtctaa tttaggtggc actctttatt aaccaaacta tttttttcta
    11581 gtacccactt gttgttccat actcattatt ctggtcataa ccataaccat tttgttcctg
    11641 tccagcgtaa ggatcataac tttgagtatc ttgacttggt gtatagtact gacttgtatc
    11701 ttctgtttgc tgataatagg tattcggatc ttggtactga tcatatgtgt tttctgaata
    11761 ggaagaataa tcggtgtacc cttcactatt cgatccatca ccgtttgtcg aatcgccatc
    11821 ttccgaatca tcaaagaaca tcattgaagc attctcattt ttcaaattag gtaatgtatc
    11881 gcttgttttt atatttaatt gtttcttcag ttcattttgg atcgaaagaa gatcattttt
    11941 tcctaaaatt tgatagtaga tatcattgat catttgtcct tcgccttgca actggtcttg
    12001 tttgattgtt tcaaacgccg gggtgtagtt cgtcgctaca tcaagcatgt catcccaatc
    12061 taagtccgtc gtcacattgt tctcaactgc ttttaaaatt tttctataat tgcttacgcc
    12121 atctaaactt aaaactttat tgacgatttt cgtcactact tcccgctgac gacgttgtcg
    12181 accgatatcg ccttctggat cttcgtgtcg cattcgagaa taggctaaac ctttttctcc
    12241 attcaatgtt tgttcaccta ctggtacatg gacaccatcc aaagtaaagt caattttatt
    12301 attcactttg atgccaccga ccgcattgat caaatcttcc atgccatcca aattgatcgt
    12361 tacataatga tcaataggaa tatcgagcag ttgctcaatt gaatccatgg ccatttcgac
    12421 accaccaaat gcgtaggcat gatttaattt atctaccgtt ccataaccta cgatattcgt
    12481 ataaatatct cggtccaaac tgatgatcgt tgattttttt tgtttcggat taactgttac
    12541 taccatcatc gtatcagaac gtccttgttc cgttcttcct aatccaccgg tatctaaacc
    12601 taatagcaaa accgaaaaag gttctttgtc atcaatgctt actctctcag aacgtttgga
    12661 ggatattcga ttagagtttt tagaaatttt gtttactgtt tggctcgctt ctcccataaa
    12721 tctgattccg tatgctgata atccggcaat cagcaaaacg aataccccta acaaggttaa
    12781 tagaactttt tgccatcgct tcataataca cctctgtttc acattttcta aaatattgtc
    12841 tcatataact gttcaatcag caaattcact ttttaatcat aagaaaactt taaaaaacat
    12901 ttttgtgtaa cgattattat tttttaaaat ttctcaaaat tcttaactat cataccatac
    12961 cgtgaaaaag atcgaaagac cgaatacacg cagttcgcaa tcgttttatc tttttttatg
    13021 tattttttcc agaaaaagcg aacaacaagg tattttccaa ataatcgtgc agtaaaatga
    13081 tcgcacatac ctttcccatc tttttaacag tctttgccta ccgttcagat tatcattcga
    13141 tttcacgaca atttcttcct atgactggtc cttttgttaa acccatcttc tattcgtttt
    13201 atttccagct cactgcatgg ctcttaaaat gactcgaact agtgattgca ttaccatcat
    13261 cttttaatgg atagatatgc tcctcttcaa agtaaaacga ttttctttta aagtaataga
    13321 attgacatgg taatgagtat gtatactagt ggtttcacaa atggtctttt attcaacatc
    13381 caaaaactga aatttcttta aaatccatta ctaacgaaga aaatgttcct tgcttgataa
    13441 ttagttagga catgtcaagt gaacaaatgc atttacttag ccaaaaa
//
LOCUS       DARPZJ010000063        13429 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.066, whole genome shotgun sequence.
ACCESSION   DARPZJ010000063 DARPZJ010000000
VERSION     DARPZJ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.066"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..914)
                     /locus_tag="SLE23_002288"
     CDS             complement(<1..914)
                     /locus_tag="SLE23_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HEI8469163.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="SLE23_002289"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="SLE23_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEI8469164.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="SLE23_002290"
     CDS             2006..2176
                     /locus_tag="SLE23_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469165.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="SLE23_002291"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="SLE23_002291"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEI8469166.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="SLE23_002292"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="SLE23_002292"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HEI8469167.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /locus_tag="SLE23_002293"
     CDS             4440..5321
                     /locus_tag="SLE23_002293"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEI8469168.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /locus_tag="SLE23_002294"
     CDS             5318..6034
                     /locus_tag="SLE23_002294"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEI8469169.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="SLE23_002295"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="SLE23_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEI8469170.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="SLE23_002296"
     CDS             6751..7752
                     /locus_tag="SLE23_002296"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEI8469171.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="SLE23_002297"
     CDS             7749..9110
                     /locus_tag="SLE23_002297"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEI8469172.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="SLE23_002298"
     CDS             9070..10221
                     /locus_tag="SLE23_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HEI8469173.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="SLE23_002299"
     CDS             10196..11365
                     /locus_tag="SLE23_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8469174.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11540..12919
                     /locus_tag="SLE23_002300"
     CDS             11540..12919
                     /locus_tag="SLE23_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEI8469175.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13200..13429
                     /locus_tag="SLE23_002301"
                     /pseudo
     CDS             13200..13429
                     /locus_tag="SLE23_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4485 a         2339 c         2923 g         3682 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgagaaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    11461 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    11521 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    11581 agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    11641 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    11701 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    11761 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    11821 ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    11881 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    11941 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    12001 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    12061 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    12121 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    12181 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    12241 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    12301 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    12361 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    12421 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    12481 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    12541 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    12601 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    12661 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    12721 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    12781 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    12841 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    12901 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    12961 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    13021 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    13081 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    13141 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    13201 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    13261 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    13321 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    13381 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DARPZJ010000064        13049 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.067, whole genome shotgun sequence.
ACCESSION   DARPZJ010000064 DARPZJ010000000
VERSION     DARPZJ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.067"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(77..149)
                     /locus_tag="SLE23_002302"
     tRNA            complement(77..149)
                     /locus_tag="SLE23_002302"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="SLE23_002303"
     CDS             530..1099
                     /locus_tag="SLE23_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEI8469176.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="SLE23_002304"
     CDS             1086..1946
                     /locus_tag="SLE23_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8469177.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="SLE23_002305"
     CDS             2136..2840
                     /locus_tag="SLE23_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8469178.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="SLE23_002306"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="SLE23_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HEI8469179.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="SLE23_002307"
     CDS             4677..5993
                     /locus_tag="SLE23_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469180.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="SLE23_002308"
     CDS             5994..6863
                     /locus_tag="SLE23_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HEI8469181.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="SLE23_002309"
     CDS             6918..7727
                     /locus_tag="SLE23_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEI8469182.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="SLE23_002310"
     CDS             complement(7830..8459)
                     /locus_tag="SLE23_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEI8469183.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="SLE23_002311"
     CDS             8629..9921
                     /locus_tag="SLE23_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8469184.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="SLE23_002312"
     CDS             complement(9997..10659)
                     /locus_tag="SLE23_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEI8469185.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="SLE23_002313"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="SLE23_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEI8469186.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="SLE23_002314"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="SLE23_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEI8469187.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4338 a         2254 c         2824 g         3633 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttctt
//
LOCUS       DARPZJ010000065        12830 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.068, whole genome shotgun sequence.
ACCESSION   DARPZJ010000065 DARPZJ010000000
VERSION     DARPZJ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.068"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(57..701)
                     /locus_tag="SLE23_002315"
     CDS             complement(57..701)
                     /locus_tag="SLE23_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8469188.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(795..929)
                     /locus_tag="SLE23_002316"
     CDS             complement(795..929)
                     /locus_tag="SLE23_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HEI8469189.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(931..3063)
                     /gene="feoB"
                     /locus_tag="SLE23_002317"
     CDS             complement(931..3063)
                     /gene="feoB"
                     /locus_tag="SLE23_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HEI8469190.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFFMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(3060..3533)
                     /locus_tag="SLE23_002318"
     CDS             complement(3060..3533)
                     /locus_tag="SLE23_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HEI8469191.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            3934..4158
                     /gene="nrdH"
                     /locus_tag="SLE23_002319"
     CDS             3934..4158
                     /gene="nrdH"
                     /locus_tag="SLE23_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEI8469192.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            4317..6476
                     /gene="nrdE"
                     /locus_tag="SLE23_002320"
     CDS             4317..6476
                     /gene="nrdE"
                     /locus_tag="SLE23_002320"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEI8469193.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            6526..7491
                     /gene="nrdF"
                     /locus_tag="SLE23_002321"
     CDS             6526..7491
                     /gene="nrdF"
                     /locus_tag="SLE23_002321"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEI8469194.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(7580..8719)
                     /locus_tag="SLE23_002322"
     CDS             complement(7580..8719)
                     /locus_tag="SLE23_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEI8469195.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(9028..9741)
                     /locus_tag="SLE23_002323"
     CDS             complement(9028..9741)
                     /locus_tag="SLE23_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEI8469196.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(9995..10696)
                     /gene="nagB"
                     /locus_tag="SLE23_002324"
     CDS             complement(9995..10696)
                     /gene="nagB"
                     /locus_tag="SLE23_002324"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEI8469197.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            10930..12462
                     /locus_tag="SLE23_002325"
     CDS             10930..12462
                     /locus_tag="SLE23_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8469198.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(12653..>12830)
                     /locus_tag="SLE23_002326"
     CDS             complement(12653..>12830)
                     /locus_tag="SLE23_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8469199.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         4104 a         2597 c         2264 g         3865 t
ORIGIN      
        1 aatctttgta aataaaaggt ttagccaagt taatattttt ttaatatttc acacaatcat
       61 tctgcaagct gatgctccgg gtaaaaaaag tttgtcatac gctgtagtgt atattcattt
      121 ccaataaaat gaacgatgtc ccctgccgta aatttagcat aggggccagg tgaaacaagc
      181 agttcttcat tatgagaaat tgcgataact gtggcgccag tcgcctgcca gatattcaac
      241 tcgctaattg aacggtccag atgcattgct ttttctgata aagataattc aaacggaagt
      301 aaaggattca tcttatgtat tcgcttcgtt tgattgacca gctgatccaa taattgagaa
      361 aaatgattca gctcatcttg ttgcttctcc acacttgcca tgatttctgc ttttgtatct
      421 tggatggatt gtacatcttg atattgcaat aggaaatctt ttgctttttc cttcgaagca
      481 acaaatgccc cacttccatg ccgtacttcc atgattccaa gatctaccag cacattgata
      541 gccttgcggg tagtctcagg agaagcattg tacgtactgg caagtgttga gcgggcatgg
      601 atcttctcac ccactttata tcggttttca acgatacgtt cggctaaatc aacagcaatc
      661 tgctggtagc gcgggcggac gatttttttc tttccagaca ttttctttcc tctttctttt
      721 tttactttcc ctcatcttac tatgctctag caaaataagc aaaaaagggg agaatagcct
      781 cttgcaacga ctgatcatcg cttgatctgt tcctttttta ctgggcaagc tgtttgacag
      841 tcatcacaat tcttaccgga ttttaaacga gtatagacaa ttgcgcctgc acttccaaag
      901 attaacacac ttaataagaa tgtcgccatc ctattcctct ccttctaatg acaatatagt
      961 ataaaactgg ttcttggatt ttggctgacg gaacaaaaca taaacgagtc ctatcatcag
     1021 taaaatagca agatacgtcc ctaacgctac ctgtccaccc tccaataagt gtcccaactg
     1081 ataaatcaca aaactaacta aataagctaa accgcattga tagcctatgg cgatccaagt
     1141 ccatttcttg gcattcattt cccgatggat agccccaatt gccgcaaaac aaggcgcaca
     1201 aagtaaattg aaggctaaca atgaataagc tgctgcggga gtatatgtgt gttgtagcac
     1261 ttgccagatt tctctgccat tttcggatac ttccgcatga ccaaacaaaa taccaaatgt
     1321 gccaataata ttttctttag cgaccaatcc tgtaatcgct gcgactgttc cttgccagtt
     1381 tccccaacca agcggctgaa aaacaactgc caggattcgc ccgaaaaagg ctaagatact
     1441 ttggtcttca gaaacaggtt gagcataaaa attataagaa gagctgaacc agatcacgat
     1501 actagaaaca aagataatcg ttcctgcttt tttaacaaaa gacttgctgc ggtcataggt
     1561 ttgtcttagg accgctgacc attgaggaaa atgatatgcg ggcaattcca tgataaaagg
     1621 agctgtatct ccagcaaaca aacgtgtttt tttcaagctg attccagaga aaataattgc
     1681 agtcatacca agaaaatagg cagaaggagc tacccaagat tgatgaggaa aaaaggcccc
     1741 tgctactaag gcaataatcg gcaactttgc agaacaaggc atgaaggttg tgaccatgat
     1801 cgtcaaacga cgatcttgct cgttttcaat cgtgcgactg gccatgacgc ctggcactcc
     1861 acatcctgta gcaatcagca taggaatgaa ggattttcct gaaagaccga atttcctgaa
     1921 aagtcgatcc atgaaaaaag cgatcctcgc catatatccg cagtcttcca gaaagctcaa
     1981 gcataaaaac aatataatca attgcggtag aaatcctaac actgctccca cgcctgcgat
     2041 gatgccgttc aagatcagct cctgcatcca tcccgctact tgccattcag ctaacaatct
     2101 gccaacatgt tctggtaacc atgtaccaaa caatgtgtca ttgatccaat ctgtccccat
     2161 tgttcctact gtttgaatag ccagataata gatcagccac atcacaaatg cgaagatcgg
     2221 caaggctaac caacgattcg ttgcaatctg atcgattttg tcactcatcg ataattggaa
     2281 agaatcattt gacacaacac agagtgtaca tagttgggta ataaattcat aacgttcatt
     2341 gaccagaatc gtctcactat cgtcgtccaa tagtttctct gttaactgga tcagttgctc
     2401 gatctctttt tgctgagaaa ctgctatctc gtaatcctct cttaccttct gatctcgttc
     2461 aaaatatttc attgcatacc agcgtttctt gccgctttgt tctcctagta catcttcaat
     2521 ttcatgtaaa gctgcttcta aacgtggatc atatgtacag ggaacaggaa tagaaggccg
     2581 cttttttgca gactcctgaa tcttttcgat tagtttttcg attccttgct ttttcaatac
     2641 gctgattggt aaaactggta caccaagacc ataggaaagc ttttctagat tgattttttt
     2701 tccttctttt ttgatgacat ccatcatatt cagaccaatg atcataggaa tgtctaaatc
     2761 caataactgc gtagttaaat aaagatttcg ttctaaattg gtagcatcaa taatgttgat
     2821 gatcagttca ggctgttcct gaaccaaata atctcttgca atcacttctt ctggtgtata
     2881 aggagacaaa gaatagatgc cgggtaggtc ctgaatatga atgttcggat tttttttcaa
     2941 cgatccttct tttttttcta ctgttacgcc cggccaattc cctacatatt gattcgaacc
     3001 agtcaagaga ttgaacaagc tagttttccc gctgtttgga tttccgacta acgcgatatt
     3061 cattcttttt cctccctttg tatcaagatt agttcggcct ctgactttcg taacgtcagt
     3121 tcataccctc gcactgtcag ttcgattgga tctcccagag gggctagttt tcggataact
     3181 atttttacat ttcgcgtcaa tcccatatcc attaaccgtc gcttcactgc gccttgtccg
     3241 tggattgcta cgacgatccc agtctctcct gcttttaatt gatcaagaga agtccagctt
     3301 tcagaggaag cagtcttttt attgacaaag atttgaccta gtatttcccg acttactgcc
     3361 actcgatgac tttttaccag taaaatggca ttgttgcctg ataaattgac gacgacgatt
     3421 ttacttccgg caacgatccc gatattttgc aaatggcgtt ttgttttttc ttctgtttcg
     3481 attcgttcga cttgataaac gaaattctgc tttgcctgcg ctaaggtctg catattgatt
     3541 cctctcttgt gaaataaatc atgtattaaa atcattcatt atatgttcta attttcttac
     3601 gtgttacgca aataaatgag aatcattctc acatagaata ctctcggtaa ttgagaatgt
     3661 caattatact tgtgatatta tgagcgaatc tttagtattg atagataaaa atgagaaaaa
     3721 aatatttctt catagttttc cacaattttt tctctattaa atttgctatt ttcccacacg
     3781 atacttgttt tcagctcttt tttcaaaaac acaaaactta gtattccaca gtttccacaa
     3841 cacaatatgt agtgtttgtt gtttgacttt tttactaaga gttttatact atctattata
     3901 gataataaga atgtgttaga ggaggcactc accatgaacg taaaaatctt ttctaaaaat
     3961 aattgtatgc aatgtaagat ggtcaaacgg tttttaacag aaaatcaaat tgcttttgaa
     4021 gaagtcaata tcgatgaaca gcctgaagca gtagactggt tgaaagcaca aggattccaa
     4081 agtgttcctg tcattacttc tgatgcagaa acagttatcg gattccgtcc tgatcagttg
     4141 cgtaaacttg ccagctaaca tgactaaaag aatcaaaacg tgatacatgg atttgaaggg
     4201 cttgagacag caccagtttt tgtcgcaaac ttccaaatcc ttttttaaag cttaaaaaca
     4261 atgcaatgat ttgcaatcaa gcatcatcaa atacgaaatg aaggttgggc gtacgtatga
     4321 gtcttaaaaa tttacaagat gtcagttatt tcaagctgaa taatgaaatc aatcggccag
     4381 tcaatggtca aatccctttg aataaggata aagaagcttt agttgccttt tttgaggaaa
     4441 atgtcaaacc aaatacgatg acttttccat ctattatgga aaaaatcaat tacttgatcg
     4501 atcaagaata tatagaagca gaattcattc aattgtattc accatcattt attgaaaagc
     4561 tatatcaatt tttggacgag caacattttt ctttcaaatc ttttatggct gcttacaaat
     4621 tttattctca atatgcgttg aaaaccaacg acggttccgc ttatctggaa acttatgaag
     4681 atcgagtagc cttcaatgcg ctttactttg cgaacgggga tgaagaatta gcacttgctc
     4741 ttgcagacga aatgatccat caacgatatc agccagctac accttctttc ttgaatgctg
     4801 gacgtaaacg tcggggcgaa ttggtgtctt gtttcttgac tcaagtcact gacgatatga
     4861 actctatcgg gcgctcaatc aactctgctt tgcaattgtc ccgtattggt ggcggcgtag
     4921 ggattacttt atcaaatctt cgtgaagccg gcgctcctat caaaggatat gagggtgctg
     4981 caagtggtgt cgttccagtc atgaaattat tcgaagatag tttcagctat tctaatcaat
     5041 taggtcagcg tcaaggagct ggcgtggttt atttgaacgt tttccatcca gacattattg
     5101 ctttcctttc agcaaaaaaa gaaaatgcag atgaaaagat tcgcgtaaaa actctttctc
     5161 ttggcgtgat cgtacctgat aaattttatg aattgacacg taaaaacgaa gatatgtatt
     5221 tatttagtcc atatagtgtc gaaaaagaat atggtgtccc attctcttat gtaaatatta
     5281 cagctgagta tgatcatcta gttgcaaatc caaacattcg caaacaaaaa atcaaagcgc
     5341 gtgatcttga aaatgaaatc tcaaaattac aacaagaatc tggctatcct tacgtaatca
     5401 atattgatac agcgaaccgc gagaatccaa tcgatggcaa gatcatcatg agtaatttat
     5461 gttcagagat tttacaagtt caaacgcctt ctgtgattaa cggcaaacag gaatatgaag
     5521 tattaggaac agatatctca tgtaacttag gctcgacaaa tatcgtgaat ttgatgcaaa
     5581 gccctaactt tggtcaatct gtgcgtacga tgactcgtgc attgacattt attacagatg
     5641 catctgatat cgatgtcgta ccaccgatcc aaaacggaaa taagctgaat catacgattg
     5701 gattaggtgc catgggctta cacacttatc ttgcaaaaga acaaatggaa tatggctcag
     5761 aggattcatt agactttaca aatatttact tcatgctgtt gaattattgg acacttgttg
     5821 aaagcaacaa tatcgctcgt gaaagaaaac aagttttcca taattttgaa aaatcagctt
     5881 atgctgacgg cacttatttc gaaaaatacg taactggaga attccagcca aaatcagaaa
     5941 aagtcaaagc attgtttgaa ggcattttta tcccaactgc tgaagattgg aatgctttga
     6001 aacaagcagt aatgaaagat ggactgtatc atcaaaatcg cttggcagta gcaccaaatg
     6061 gctcaatttc atatatcaac gatacgagtg caagtattca tcctatcact cgcatgatcg
     6121 aagaacgcca agagaagaaa atcggtaaaa tttattaccc agcgccttat ctatccaatg
     6181 agacgattcc gtattacact tctgcttatg atatggacat gcgtaaagta atcgatgttt
     6241 atgcaacggc acaacaacac gtcgatcaag gcatgagttt gactttattc atgcgttctg
     6301 aaatcccaga aggcatttat gaatggaaga caacaacgaa gcaaacgaca cgtgatttga
     6361 atattttaag acattacgct ttccacaaag gaatcaaatc catttattac gtacgtacct
     6421 ttactgatga tgcagaagaa atcggaagca atcaatgtga aagctgcgtg atctaatatc
     6481 atagatagat tcgcttattc atattttaat taaaggagca ttctcatgtc agaaacatat
     6541 tatgaagcaa taaactggaa tgaaattgaa gatatcattg ataaatccac ttgggagaag
     6601 ctgacagagc aattttggct agatacacgt atcccacttt caaatgacct agatgattgg
     6661 cgtacattgt ctcaattgga aaaagataca gtaggacatg tatttggcgg tttgacactg
     6721 ctagatactg tccaatctga aagtggcatg gatcagttgc gtaaagatgt ccgcactccc
     6781 catgaagaag ccgttttgaa caatattcaa ttcatggaat ccgttcatgc caaaagttat
     6841 tcttctattt ttagtacact gaatacgaaa aaagaaatcg aagaaatttt tgactggaca
     6901 aatacgaatc cttatctgca aaaaaaagct gagcgtatca atgaaatcta caaacacggt
     6961 acaccgctag aaaagaaaat tgccagcgtc tttttagaaa cattcttgtt ctattcaggt
     7021 ttttatactc ctctttatta tttaggaaac aacaaattgg ctaacgtagc agagatcatc
     7081 aaactaatca tccgagatga atctgtacat ggaacctaca tcggttacaa attccaatta
     7141 ggattcaacg agttacctga agcagaacaa gaaacgttaa aagactggat gtacaatctt
     7201 ctttatgagc tttacgaaaa cgaagaacgt tatacagaag aattatacga tccaatcggc
     7261 tggacagaag aagtcaagac attcctacgc tataatgcca acaaagcatt gatgaaccta
     7321 gggatggatc cactctttcc agatactgcc aatgatgtca acccaatcgt aatgaacggg
     7381 atttcaacag gcacaagcaa ccatgacttc ttctcacaag tcggaaacgg ctatttgtta
     7441 ggtcatgtag aagcgatgaa agacgacgat tatttgattg gattggaata aggatttatt
     7501 ttaattcaaa aatttttcga aaaataaaaa gagtttagcg tacagatatt ttaaatgtac
     7561 actgaactct tttttatgct tattcacttg tttcttccag cacttttgga ctgtctaact
     7621 tttccgaaac atgttccatt cttctcaata aatagatttt ccggatattt aatattatcg
     7681 tcttaatcac tgcatagaca ggtatgcaaa tcagcatgcc taatattcct gcgacacttc
     7741 ctgctccaat caataccaag atgatcgtca aaggatggat attcattgat ttcccaaata
     7801 acaacggctt gatcaaattt ccatctaatt gttggatcac taaaatcgac aacgccatat
     7861 acaaagcttg aaatggagag ataaacaaac cgacaatgat tgctggtacc gctccaataa
     7921 aagggccgac atacgggata atattcgtga ttccgcaaat gaccgcaagc aacaagctat
     7981 aaggctgatc gaatattctc attgccaaaa agctcattac accaataatc aaagcatcta
     8041 agatcgtact gctgatatag gcagataatg tttcgtttaa ttcttttacc gtttggcgta
     8101 actctttacg aatcgctttc ggaaagaagt gagacaacgc atcaataaat ttgtgcccat
     8161 ccttgaacat aaatagcaaa ataaatggaa cggtaaataa caaaataaaa aattgcatca
     8221 taaatgaaat gatttttgag acacttgcag ataaactgac taatatgata ttgaacaaat
     8281 tactaagaga taaatttgct gatgctaatt gttcttccaa attgaaattt ttaaactctt
     8341 cccgctgcgc caattcattt aaccatttgc ttgtttcatc tgcatacatt ggcaagctct
     8401 gggtcaattg aattgtctgt tccattaact gaggcactac attcatgaca gttaaaacaa
     8461 ctaaaatgat tacgaccaaa aacgtcaata aaaaaccgaa cactctcggg atccgatgct
     8521 tttcgagaaa aacaacgatt ggatcgaaca tataatagat aaaaccagca acaagcaatg
     8581 gtaaaaaaat tgccgaaagc attttcaata ttggactaaa aatattcggc atttgtaaaa
     8641 taaagtacac gccgatgatc gtgagtacta gctccactgt ccagaaaaat aattttgatt
     8701 gtttaaaacg tgattgcata catctcctcc aaggtccttt gatacttcta ttctatcatt
     8761 taacaaagag ttacgcgctg agattttcat ttgcttaaaa aaaacaaaaa aaataaacat
     8821 attttaatga gtagacgagt acttaaacaa aaacacggtt tggagtagtg acaaaaatta
     8881 tactgcagtc cctttttcca aataaacggt gttcaaaagc ttgcatcttc gtaataagcc
     8941 cagccaaacg aaaaatataa ggaactattt ttatttggct gggcttatta cttgatgtag
     9001 gacatctatt ttacaacctc agatcattta ttgcgcaata ctgactaaat gcaactttgt
     9061 gatatttttg tgtacggaca actcctcgat cacatcggca taagtgagcc cttttggaag
     9121 atcaatcgta tagatatttt tgtacactcg gtagtcatca acgaatttta cgtcaaaatt
     9181 cacatcttcg attacgatat ttttctcttc aaaataatcg gtaagaaaat ctttggtttc
     9241 ttttctatgg ataaattgga tttctaactt tttagtcgta ggtacatgga tcacgcgttt
     9301 cactactgtg agtgcaatag caatcccgat aaaactgatg atcgcaatgg aatagtaacc
     9361 catgccgatg gcgatcccta atccagcaat tgcccataaa gaagcggcag tcgtaagtcc
     9421 cgtcaccgat tgtttcgtga cgatgatcgt tcccgcgcct aagaaaccga caccactcac
     9481 cacttgagca atcagccttg cttcatctga acgaatcgtt ccagcaagct gtggatactc
     9541 taaagcatct cttaatgcac cactagcgat ctcaacttgg atcaatgcaa tgatacatgc
     9601 tcccatacaa actaaaatat gcgtacgcat acctgctgga cgatttttat attgtcgttc
     9661 aaaaccgatt gctccgccaa atagcatagc gatccctaaa cgtaaaataa tctctggaat
     9721 tgtcaatacc atatcattca tctaaacacc ctccagtcca atatatcatg tctgaaagga
     9781 gcagacaaaa aaagtgcaat ttttacctct tacgaaaaaa ggactgtgac aaaatttttg
     9841 tcatagtcct ttttatgaat aaacggtgtt caatcagctg accctcggta ttactcaaca
     9901 aacggcaaaa tatggggagc tatttttcct ttgtcttctc taatactcag gtcaaaacgc
     9961 tgatttcaca acctctttag cctactattg aaaattacaa cttacttgct gcttcttcat
    10021 cgatgatcac aacaacattg tcgtgatttt gcaatacact tgctggcaaa tgattcgtta
    10081 caggtccttc aatcatccct ttgattgcat cagctttgct ttcgccaaat gccatcaaga
    10141 cgatttcttt acttttcata attgaaccga ttcccattga aacagctttt gttggtacat
    10201 cttctgcttt atcgaagaat cgtttgtttg cattgattgt tgattctgtt aagtcaacta
    10261 ctgaagtcgt tccgtcaaat gaagcaccag gttcattgaa accgatatgt ccattttgcc
    10321 cgattcctaa gatttggata tcgattggat gtgcatcgat gatttgatca tactttttgc
    10381 atgctgcttc cagatcttct gcttttccat ctggtacaaa cgtttctttg aatggttttt
    10441 tatcaaataa ttggacatcc atgaaatgac ggtagctttg ttcatctgaa ccgcctagtc
    10501 caacgtactc atctaagttt acagaagtca tttcactgaa atccaaatcg cttgaagtca
    10561 tttctttata taaagtaact ggtgtgcttc ctgttgccaa tcctaatact tttgcacctt
    10621 tgttcatacc ttctttgatg atttcaaatg ctttttttcc gccttcttca gcgtttttta
    10681 cacgaatgat ttccatagtg attgctcctt tatattttgg tatagcccaa ttatagcatt
    10741 ctttttttct ttttacaata attagtatag accaaattgc atttttttca ttttcttgac
    10801 aataaatagg aatccgtgtt aggtttcata agatggttca atcaaacaat ccatgttgca
    10861 tgaaaaccaa gcaagtgatt cactgtggac gctttatgtc tgcagttttt ttatgaaaaa
    10921 ggagttatta tgagtatact gacattaaac aacattaccc agcaatttgg cgacaaaatc
    10981 ctctatgaag gtgtcgatct gcaattaaat gctggcgaac atcttgggct gattggacaa
    11041 aacggagccg gtaaaagtac attgattaaa atcatcactg gtgagatctt accagatgac
    11101 ggacagatcc attggcaaaa aaatattcac aaaggttacc tcgatcaata tgtggaagtc
    11161 gatgaaacat taacaatcga agaatttcta aaaactgcgt acgcaaaaga atacgaaaag
    11221 gaagaaaaaa ttgcttttct ttaccaaaca tatagcgaga ccttcgatga ttccttgctg
    11281 gaaaaagctg ggaaactcca aacggaatta gaccaaggag tgttttatca aatcgacacc
    11341 ttagttgctg agatgagcag cgggttgggg atcgatgtct taggtttaga ttcactgttg
    11401 aaaaatctaa gtggtggaca acgttcaaag gtgattttag caaaactact tttagaaaac
    11461 ccagatgttc tgatcttaga tgaaccaacc aatcacttag atgatcagca tatccaatgg
    11521 ctgacgcagt ttcttcagga ttttgacggt gcgtatatcg tgatttccca tgaccaagaa
    11581 tttcttgatc agatcaccac ccatatcgca gacatcgagt ttggaaagat tactaagtat
    11641 actggccatc taaaacaagc attgaaacaa aaggaacaaa atcgcgaaag ctatttgcgc
    11701 caatatcatg ctcaacaaaa acaaatcgaa aagaccgaag cttatattcg aaaatacaaa
    11761 gccggttccc gatcaacgat ggcaaaaagc cgacaaaaac aattagataa aatcgaacgg
    11821 ctgacgcctc cagcttcagc aagtaaagct gtctttgatt ttccattctc gcctattgtc
    11881 acgacattag cagtggaaac aactgattta gtcatcggat atgatcgacc gctacttgca
    11941 cccatcaatt tgaccatccg ctttggtgaa aatattgcca ttcgaggctt caacgggatt
    12001 ggaaaatcta ctttattaaa aacactgatc ggtgagattg aaaaaataag tggcgatttc
    12061 cacttcccag ataacacaaa aatcaattac ttttcacaag atctgtactg ggaaaatcca
    12121 ttagaaacac cactacaata tttaagcagt caatttccaa aagcgactat caaagaatta
    12181 cgtcgccaac tagctaaagc agggttagtt aatcaattag caagtgaacc tctcactaca
    12241 ttaagtggtg gggaacaaac taaggtgaaa cttgcacagt tgacaatgaa ccaaggtaat
    12301 ttactgattc tcgatgaacc gacgaaccat atcgatcaag aaacgaaaga aagcttacaa
    12361 gacgggatac agaaatttcc aggaacagta atcatcgtct ctcatgaaca agaattttat
    12421 caagatcttg tgcaacgagt cattgagatt gaaccaaaat aaacgtttga ttgaatagtt
    12481 gaaaaaaagg agctgtgaca aaagttttgt cacaactcct tcttctgaat aaatggtggc
    12541 caattagctg accttcggta ttagctcaaa aaacggcaaa atatgaggag ctatttttat
    12601 ttggctattc ttattacttg atgcagaaca gcttttcaca acctcttttc gtctattttt
    12661 tattttcgag atttctcttt cctttaaaaa caactgtttg aaagaagaac gcacatcctt
    12721 gaaaaacaag cccgctaacc gttacaccta accagccata ctgctgccac attgtcgtcc
    12781 ctagcaatga accagccgca cctccaataa agtacataaa cataaataca
//
LOCUS       DARPZJ010000066        12606 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.069, whole genome shotgun sequence.
ACCESSION   DARPZJ010000066 DARPZJ010000000
VERSION     DARPZJ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.069"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            114..1082
                     /locus_tag="SLE23_002327"
     CDS             114..1082
                     /locus_tag="SLE23_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEI8469200.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            1179..1472
                     /locus_tag="SLE23_002328"
     CDS             1179..1472
                     /locus_tag="SLE23_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEI8469201.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1590..1826
                     /gene="secG"
                     /locus_tag="SLE23_002329"
     CDS             1590..1826
                     /gene="secG"
                     /locus_tag="SLE23_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEI8469202.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1929..2684
                     /locus_tag="SLE23_002330"
     CDS             1929..2684
                     /locus_tag="SLE23_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8469203.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2687..5044
                     /gene="rnr"
                     /locus_tag="SLE23_002331"
     CDS             2687..5044
                     /gene="rnr"
                     /locus_tag="SLE23_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEI8469204.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            5066..5530
                     /gene="smpB"
                     /locus_tag="SLE23_002332"
     CDS             5066..5530
                     /gene="smpB"
                     /locus_tag="SLE23_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEI8469205.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5832..6551
                     /gene="atpB"
                     /locus_tag="SLE23_002333"
     CDS             5832..6551
                     /gene="atpB"
                     /locus_tag="SLE23_002333"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEI8469206.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6604..6819
                     /gene="atpE"
                     /locus_tag="SLE23_002334"
     CDS             6604..6819
                     /gene="atpE"
                     /locus_tag="SLE23_002334"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HEI8469207.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            6910..7434
                     /gene="atpF"
                     /locus_tag="SLE23_002335"
     CDS             6910..7434
                     /gene="atpF"
                     /locus_tag="SLE23_002335"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEI8469208.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            7421..7963
                     /locus_tag="SLE23_002336"
     CDS             7421..7963
                     /locus_tag="SLE23_002336"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEI8469209.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            7986..9542
                     /locus_tag="SLE23_002337"
     CDS             7986..9542
                     /locus_tag="SLE23_002337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEI8469210.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            9556..10458
                     /locus_tag="SLE23_002338"
     CDS             9556..10458
                     /locus_tag="SLE23_002338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEI8469211.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMTILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10481..11887
                     /gene="atpD"
                     /locus_tag="SLE23_002339"
     CDS             10481..11887
                     /gene="atpD"
                     /locus_tag="SLE23_002339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEI8469212.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11901..12323
                     /locus_tag="SLE23_002340"
     CDS             11901..12323
                     /locus_tag="SLE23_002340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEI8469213.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4213 a         2202 c         2780 g         3411 t
ORIGIN      
        1 atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat cctatggatc
       61 ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt acaatggtta
      121 ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt ctttcttatt
      181 tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg tatgaagaca
      241 ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa cgacaaaaat
      301 tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc aaaagttatg
      361 acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat aaatgggtca
      421 tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata ggtaaaagat
      481 atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga gaaagtgaag
      541 gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg atccaactca
      601 tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg ggagcttcta
      661 cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt attttagaca
      721 gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc actgtctttc
      781 ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc ggttactcct
      841 taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta ttagtcatcc
      901 atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa aatgctacgg
      961 caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca tcgatgaaag
     1021 atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata acgatgaatt
     1081 aattttctct tcttttttgt aagtaattcg aggataaata attgtttata gatcaggaga
     1141 ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg gcatatggaa
     1201 atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag atcggagaaa
     1261 tgacatggtc agatgcgggc ccagacatca tgatcattga ccatacattt gtagatccag
     1321 catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa ttagcaagac
     1381 gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt gaaaagaaac
     1441 cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt ttgaactttc
     1501 agctgttatt ccatttatat agagttgtca cggactttta tctatgataa agttaaagag
     1561 acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga atcgtgatcg
     1621 ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa aatagtgcag
     1681 cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct cgcggctttg
     1741 aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc ttattatttg
     1801 tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg cgggcggctt
     1861 tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg taaaatgagg
     1921 cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa catggaaagc
     1981 gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga atgctcgcac
     2041 gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga cacggaacaa
     2101 tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac actaaaaaag
     2161 ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga ttatcaatgg
     2221 gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc ggttttttct
     2281 gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa tacgtacgtc
     2341 aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca gttgcttacc
     2401 gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc gtagaaagta
     2461 ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat gaaatgatcg
     2521 accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg acacttcaat
     2581 ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa ttagaaaaag
     2641 acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga caaaagaaac
     2701 gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt tttctatgga
     2761 agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac tagtacaaac
     2821 gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa aagtgaaact
     2881 tcctttaaaa ccaatcttga tcgaaggaac atttcgagca aatgaacgag gatttggatt
     2941 tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga ctggttttgc
     3001 aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag atatggatcg
     3061 cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt tagcagggga
     3121 attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg ttgttatccc
     3181 gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag ttcgtccagt
     3241 tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt atgcgactag
     3301 tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca tggatatcct
     3361 ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat tgtctgaagc
     3421 agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag atttaagaaa
     3481 tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg cagttacggt
     3541 taaaaaatta gataacggta attattttct tggagtacac attgcagatg tttcttacta
     3601 tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa gtgtatattt
     3661 gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct gttcactgaa
     3721 tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa atggacaagt
     3781 agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga cctacacagc
     3841 tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg ctcagctcgt
     3901 acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc gaatcaaacg
     3961 tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg aaggacaccc
     4021 aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat ctttcatgct
     4081 tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt ttatttaccg
     4141 aatacatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg cttcagcttt
     4201 gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac agcatgtgat
     4261 cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc taagaagcat
     4321 gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg cagattacta
     4381 cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc gtctgatccg
     4441 ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg aacttcctga
     4501 aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac gtgaagtaga
     4561 ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg atgggatcat
     4621 cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag agggattgat
     4681 ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt tagctcttgt
     4741 aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa aagtagtcaa
     4801 agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag aggttacagc
     4861 gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa aacaagcagg
     4921 aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta agcaaacgtt
     4981 cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaaaaaga aaaagaaaaa
     5041 ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa ttgcacaaaa
     5101 caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga tggtcttgca
     5161 aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg gatttattcg
     5221 cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg aacaaggaaa
     5281 tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa aacaaatcat
     5341 ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa aagtctatat
     5401 tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat cttatgataa
     5461 acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat taaaaaattt
     5521 ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt acttaatgat
     5581 aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt cttagatcag
     5641 gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa agtgtctaat
     5701 tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg tggttagaaa
     5761 ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc ggggaaaaga
     5821 ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt tggtttgatg
     5881 gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta gcttactttt
     5941 ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa tgggtcattg
     6001 attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc aatttccatt
     6061 tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt ttagtaacaa
     6121 aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac ccgtttgtta
     6181 ctttaacttt ggcatttata atgatcttac ttactcactt atttggggtg aaaaagttag
     6241 gcttcaaagg atatttcgta aattcgttct tgaaaccata tagttttatg tttccgatga
     6301 aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat gggaatattt
     6361 atgcggggga agttttgcta accttgattg caaaaatggt aataagctta ggctggttct
     6421 cattgccgtt agcaattcca ttagagatgg tctggatcgc attctccttg tttatcggaa
     6481 gcatccaagc atttgtcttc gttactttat ctatggttta tatgagccat aagattgaag
     6541 tggaagaata atattcgttt taaaaacaaa ctactattta tctaatttag gaggaaaaca
     6601 attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg agccggttat
     6661 ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc tgaaatgtct
     6721 ggtcaattcc gtacaacaat gtttatcggg gtagctctag tcgaagctgt tcctatctta
     6781 ggggtagttg tcgccttgat tctagttttt ggtgtttaat tgaatcagta ttaaggcaga
     6841 aacaatttgg tttgttactg cttttttaca tgaaaactag aagtacttca aagaaaggaa
     6901 ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat gttaggaaat
     6961 gtcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca ttttgcttgg
     7021 ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga tttggattct
     7081 gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca acaattgtta
     7141 gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg agaattaagc
     7201 cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag taaagcccaa
     7261 gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga tgttgcagaa
     7321 ctatctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga aatgcacgaa
     7381 tcattaatca atcaatatat cgaaggtcta ggttcttcaa atgaaactag ataaatatac
     7441 agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa atcaagcaga
     7501 agaaatctat caagatctcg taagcttacg tcaaatctat gaacaagtac ctggattagg
     7561 taatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca tggacaagct
     7621 tgttagtggc tatgatggaa tcgttaaaaa ctttttagaa gttgtttatg cgtataaccg
     7681 aatggatgat cttttgttca tgatcgaaga atatgaacgt cgatatgatg aacatcaagg
     7741 tttgctgttg ggaagtgtca caacagcagt tccactttca gacgaacaac gaatacaatt
     7801 agaaaagaat gttgcaaaaa caatgaacta tcaatcagtc gaattaaaac aaatcgttga
     7861 ttcttctatt attggtggcg cgattgttga agctaaccat cgagtaatcg acggaagcat
     7921 tcgcacgcaa ttagaaaata tgcgtaatca attaaataga tagtacaaag aggtaggtga
     7981 atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa attgaaaatt
     8041 atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt gacgggatcg
     8101 ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt tcaaatggct
     8161 catacggaat ggcgcaaaac ttagaatcaa atgatgtagg tatcattatc cttggcgatt
     8221 tcgagtccat tcgtgaagga gataaagtaa aacgaacagg aaagatcatg gaagttccag
     8281 ttggagaggc cttgatcgga cgggtagtta atccgctagg tcagccaatc gacggactag
     8341 gtgaaatcgt tactgacaaa gctcgtccag tagaagcaat ggcaccaggc gttatgcaac
     8401 gtaaatctgt taacgaacca atgcaaacag gtctaaaagc aatcgacgct cttgtaccaa
     8461 tcggacgtgg ccaacgtgaa ttagttatcg gtgaccgtaa aacagggaaa acttctattg
     8521 cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat gtagcaatcg
     8581 gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat ggcgcaatgg
     8641 attacacaat cgttgtgaat gccggtgcgt ctcaaccagc gccgttgctt tatatcgcac
     8701 catatgctgg tactgcaatg ggtgaagagt tcatgtacaa cggtaaacat gtcttgatca
     8761 tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg ctacttcgcc
     8821 gtccaccagg tcgtgaagct tatccagggg atgttttcta cttacactca cgcttattgg
     8881 aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc ttaccatttg
     8941 ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt tcgatcactg
     9001 atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca gcggttgatg
     9061 ccggactatc tgtatctcgt gtagggggtt ctgcgcaaat caaagcaatg aaaaaagttg
     9121 ctgggacttt acgtctagac ttagcaagtt accgtgaatt agaagcattt acacaattcg
     9181 gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt acagtagaaa
     9241 tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg attttgtatg
     9301 ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac ttcgaacatg
     9361 aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc cgtacaacaa
     9421 aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa gacatgttct
     9481 tagctacaaa aggaaataat tcctctacag aagataaatt gaaatccatt caaaatgcat
     9541 agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat cgcttcaacg
     9601 aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa gttgacaaaa
     9661 tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga aatcgttacg
     9721 catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg ggatatcaat
     9781 tacaacagca tgctgctcag ccgtcctgtt aagaaaactg gttatatcgt catcactgca
     9841 gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat gactatttta
     9901 gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg aactggtgca
     9961 gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct atctgatcag
    10021 ccaagctttg atgaagtccg caaaatcgta aatatggcaa caactatgta ccaaaacgaa
    10081 gtattcgatg aattatacgt atgttataac catcatatca attcgctaac tagtcagttt
    10141 cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac tactttcgaa
    10201 caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt gcctcagtat
    10261 gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca tgctgctggt
    10321 atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga gctgacggtt
    10381 tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat tgttgccgga
    10441 gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag gcaagattgt
    10501 tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct taccagatat
    10561 caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg ttcttgaagc
    10621 agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa cagatggttt
    10681 acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg taggtaaaga
    10741 aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa cacctttccc
    10801 agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg aattaagtac
    10861 aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc catatttaaa
    10921 aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac tgatccaaga
    10981 actgatccat aatatcgccc aagaacatgg tggtatttct gtatttactg gtgtaggtga
    11041 acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag ttatcgaaaa
    11101 aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc gtgttgcttt
    11161 gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg tactgttgtt
    11221 tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct tgttaggacg
    11281 gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc aattgcaaga
    11341 acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct atgtgccagc
    11401 cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg cgacaaccaa
    11461 cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat tggcttcttc
    11521 ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag caacagaagt
    11581 ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct taggtatgga
    11641 tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc aattcttctt
    11701 gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat atgtccctgt
    11761 agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg atcttcctga
    11821 agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga aaacactagg
    11881 ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta actcctgccg
    11941 gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct ggtgagcttg
    12001 ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa gttcgtgtaa
    12061 aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga atcatggaag
    12121 ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt gatatcgatg
    12181 tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa gcaaaagcaa
    12241 aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca atcaatcgta
    12301 tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt taagaacagt
    12361 aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt tacgaaaatt
    12421 gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt ctggaacacc
    12481 gtatatcaga ggttgtaaaa tcagcgtttt gtcctgagta ttagagaaac aaatggaaaa
    12541 gagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga ttgaacaccg
    12601 tttatt
//
LOCUS       DARPZJ010000067        12597 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.070, whole genome shotgun sequence.
ACCESSION   DARPZJ010000067 DARPZJ010000000
VERSION     DARPZJ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.070"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(10..159)
                     /locus_tag="SLE23_002341"
     CDS             complement(10..159)
                     /locus_tag="SLE23_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469214.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            555..755
                     /locus_tag="SLE23_002342"
     CDS             555..755
                     /locus_tag="SLE23_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8469215.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1323..1886
                     /locus_tag="SLE23_002343"
     CDS             1323..1886
                     /locus_tag="SLE23_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469216.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1947..2291)
                     /locus_tag="SLE23_002344"
     CDS             complement(1947..2291)
                     /locus_tag="SLE23_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469217.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(2388..2633)
                     /locus_tag="SLE23_002345"
     CDS             complement(2388..2633)
                     /locus_tag="SLE23_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8469218.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(2703..2957)
                     /locus_tag="SLE23_002346"
     CDS             complement(2703..2957)
                     /locus_tag="SLE23_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469219.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(3121..3444)
                     /locus_tag="SLE23_002347"
     CDS             complement(3121..3444)
                     /locus_tag="SLE23_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469220.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            3631..3704
                     /locus_tag="SLE23_002348"
     tRNA            3631..3704
                     /locus_tag="SLE23_002348"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3665..3667,aa:Ile,seq:cat)
     gene            complement(4089..4586)
                     /locus_tag="SLE23_002349"
     CDS             complement(4089..4586)
                     /locus_tag="SLE23_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEI8469221.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(4626..5435)
                     /locus_tag="SLE23_002350"
     CDS             complement(4626..5435)
                     /locus_tag="SLE23_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8469222.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            5769..6626
                     /locus_tag="SLE23_002351"
     CDS             5769..6626
                     /locus_tag="SLE23_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEI8469223.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            6619..7521
                     /locus_tag="SLE23_002352"
     CDS             6619..7521
                     /locus_tag="SLE23_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEI8469224.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            7554..7904
                     /locus_tag="SLE23_002353"
     CDS             7554..7904
                     /locus_tag="SLE23_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8469225.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7953..8876
                     /locus_tag="SLE23_002354"
     CDS             7953..8876
                     /locus_tag="SLE23_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEI8469226.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8954..9847
                     /locus_tag="SLE23_002355"
     CDS             8954..9847
                     /locus_tag="SLE23_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8469227.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9885..10448
                     /gene="amaP"
                     /locus_tag="SLE23_002356"
     CDS             9885..10448
                     /gene="amaP"
                     /locus_tag="SLE23_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEI8469228.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            10462..10650
                     /locus_tag="SLE23_002357"
     CDS             10462..10650
                     /locus_tag="SLE23_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEI8469229.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            10663..11565
                     /locus_tag="SLE23_002358"
     CDS             10663..11565
                     /locus_tag="SLE23_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8469230.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            11597..11839
                     /locus_tag="SLE23_002359"
     CDS             11597..11839
                     /locus_tag="SLE23_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8469231.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(12095..12466)
                     /locus_tag="SLE23_002360"
     CDS             complement(12095..12466)
                     /locus_tag="SLE23_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469232.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4461 a         2113 c         2366 g         3657 t
ORIGIN      
        1 ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg taacacctgt
       61 cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat ctgtatccaa
      121 ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc tttctttaaa
      181 tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag tataccacca
      241 attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata aaagcaaata
      301 aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg attcgaagac
      361 aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta gaaaaagcat
      421 gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc tacatagata
      481 aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg atacgtatca
      541 ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac aaaggttttg
      601 gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct atccaaggtg
      661 acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa gatggtcaac
      721 gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt aaccgtcttt
      781 tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa tgggctgaat
      841 agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga aaatacgaat
      901 aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc ttgaaaatga
      961 atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt ggtctgtcaa
     1021 ttaatgaaaa agtaaaaaag aatatgttct aggaagaggg cggcacatct aaatttttaa
     1081 gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt gaaggaatac
     1141 gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca agtgatgaaa
     1201 gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta ataatttttt
     1261 tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt ttaaaaataa
     1321 ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa tatttagaaa
     1381 ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc tattttcagg
     1441 gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta gcaatggcag
     1501 gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa gccacgacag
     1561 aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga cgatgcatgg
     1621 gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg tgtagaagaa
     1681 gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca tcgtatacag
     1741 acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg tctagggaag
     1801 ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat gaagataacc
     1861 ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa tgaagtaaga
     1921 ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg ctccaaattt
     1981 gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac gttgcgctct
     2041 acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg atttttccac
     2101 tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg atgatattgg
     2161 aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt ctttccccag
     2221 ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg acgaggaagc
     2281 tttgaaatca atttttcatg ccataatcac atagaaatgt ctcctttata tatagattgt
     2341 taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca cttcagtttg
     2401 cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa gtcagcgata
     2461 tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg atatttgaat
     2521 aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc agttcttaag
     2581 aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact catttaatca
     2641 cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc aatcaatagt
     2701 actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa agacaaaacc
     2761 agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta attaaaaact
     2821 ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg ttctttgttc
     2881 caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca aaacaaaact
     2941 ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa gataacatgt
     3001 tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat caatgaaaaa
     3061 tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa tgtgtcttat
     3121 ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata aaaagaggac
     3181 gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa catatttaac
     3241 aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca tcatgacaag
     3301 aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc ctgaggtttg
     3361 ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa tcgcaataaa
     3421 tggcaaaata atcactccta acattgagaa taaataaaag aataacattt tttctaaaat
     3481 aagcaaataa aaattaaagt aacaaaatag ttatgacaca agtaaaagaa ataagaataa
     3541 caatattatt ttacttatat tttgaaactt gtgagagttt gtcattcgtg ctatagttga
     3601 aaagtaacaa aaataaattt tatttatgat gtacctttag ctcagttggt tagagcagac
     3661 ggctcataac cgtccggtcg taggttcgag tcctacaagg tacataagag gttgtgaaaa
     3721 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttact
     3781 tggctgttct tattactgca gatgcaagct tttgaatacc gtttaaggaa gaggttgtga
     3841 aatcagcgtt ttgacctgag tattagctta acaaacggaa aaatagttcc tcatattttg
     3901 ccgtttgtta agctaatacc gagggtcagc tgattgaaca ccatttaaga aagaggtcgt
     3961 gagcctgccg tttcactctg tgtcataaaa aagccaatct actttgatag aaaaagcacg
     4021 taggactaaa acagttctgc gtgctttttt tattgtgtgt taaatatcgt aaatgaagat
     4081 agatattttt atgattcgac gatagagacg ttgaaatctt tcaacagctc taaagcggat
     4141 tctccgtgtt ttctactgga gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa
     4201 gcactctgca ggcctatcag attagagagt acacacaagt ttgtttcaat cccgactact
     4261 tcgatctctt tttgttcttc tttgctttca aataaagttt cctggatttc agctaaagtt
     4321 tcaggtggaa tcgtaaagta atacttttta atcactcgtt cattttcttg tggagaaaga
     4381 agagggatca attgcaaatc ttctcgttct tcttctttgt ccttcagttc aactggtata
     4441 tcccgtgtga agagaatata ttcattattt tggcgtgctt tagctaatct ttgagcaata
     4501 cgttctgcca attgatctga ctctggaata taaaattcgc tgtttggatc aagaatatga
     4561 ttttgcatat caataataac taacattttc tttcctccta cattcatatc gtcattttat
     4621 tctttttaat agaagttttt taaaatataa gcaacaccag cttcttcatt cgtcagtgtt
     4681 acttggtttg caatttcttt tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg
     4741 ctgtaattca acatatcaat gtcgttttct tgatcgccaa aagccatgat gtcactcgat
     4801 tcgattccaa ggtaatccgc cagaaaaaca agtgaatgag ctttagtgat acctgtaggc
     4861 gtgatttcta agaaatgcgg atcagagaat actgattgga taccatctgc ttgcagatct
     4921 ctttgtagct tctgtagttt ttcttcactc ttatctgtta atgctaattt aagatagcta
     4981 agagaaggat cttccaacat atttaaaatt tgatcaaaag aatggttctg taaattgaaa
     5041 tgttcataat aagggtcatc tttgactaga tttgattcat cgaatgtcag ctgatcatct
     5101 tgggtttctc ggctagcaat gatggatatt ttcgcttctt gagcatagaa gaaggctttt
     5161 ctcagtgtat cgctatctat ttttgaacgt ctgagaactt tcgccatttt tccatccttc
     5221 atttcagcaa tcagtgaacc attggaagaa atcaaatagc caccgattcc taattcggaa
     5281 aaaatatctt tagcagaaat gctgttcctt ccggtagcga cggttacgat tccgccattt
     5341 tcatcaaatt tccgaagtgc ttggatattt tcttctggta tctttccatt tcgatcaagc
     5401 aaggtaccgt ctaaatcaat cgctgctagt ttcattttat cttcctactt tctttttaca
     5461 tatctatttt cctgttacct taagattaaa tgagaattta aaaaaatgaa actaacttgc
     5521 tttgtcatta tgaatttttt caaaaaacat tcttaagaaa aaggtggcta tatatagtag
     5581 tttttggtca atacctttga ataaaaagcc atgaaaaacg aatagttagc gcttaccgat
     5641 gcgttttgtg ataaaaaaat tttaaaatat tcaatgaaaa caaagcatat attttgcttt
     5701 aaaaccaaat gaggaatatt ctagatgtag aacaggttag aaaaagatta gaaaaaggag
     5761 tgattttgat ggagaagaga tacggcgtag ttcctgtggt aactgcttca gacgaaaatt
     5821 atgctcctta cttgagcgtg atgatcgcaa ctgcattaga aaattgcaat aaaacaagac
     5881 gcataaaatt ttatgtgatt gacgatggtc tatcagaata tagtaaagaa ggattggaag
     5941 aaacggtaaa taaatattca agtaatgcaa gtatccaatt cctgacagtg gaaaaagata
     6001 tctacgaaga cttcctagtc agtgaccata tcacaactac cgcttactta agaatttctt
     6061 taccaaactt attagctaaa gaggattata agaaagtcct ttacttagat tcagatgtgt
     6121 tagtactaga cgatatcgta aaactatatg atgagccgtt aaatggaaaa acaatcggcg
     6181 ctattatcga tccaggccaa gtgaaagctt tggaaagatt aggaatcgat tccgatgact
     6241 tgtacttcaa ttcaggagtg atggtgattg acattgatca atggaataaa aaagaaatta
     6301 cagaaaaaac tatccattac ctcagtgaaa atggcgatcg aatcatctat cacgaccaag
     6361 atgctttgaa tgctgtactt tatgaagatt gggaacaact tcatccaaaa tggaacatgc
     6421 agacttcgct gatttttgaa cgtcatccag caccaaatga aaaatatgaa cgtcagtata
     6481 aagaaggaaa tgaaaaacct tcgatcgttc actttacagg acatgataaa ccttggaata
     6541 cgttgaaaga tcatccgtat accaatttat acttaaaaaa attagcacac agtactctaa
     6601 cgaaagtagg cgagatcaat gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca
     6661 aaattcgtac cacatttagc tgcattattt gtctcagtat tagataattg caacccgtct
     6721 aaatttgttc ggttctatgt gattgacgat gatatcgatt ttgaaagtaa acagctttta
     6781 cgcttctcag tgaaaaacgc acgaatgaac tcagatgtgg aattcttgaa aatcaataaa
     6841 gaattcttta caaatgtggt aatcagcgat cgtattccag aaacagctta ttatcgtatt
     6901 gcgattccgg aattgttccg cggcacagaa gttgaacgta tcttatatat ggattgcgac
     6961 atgatcgctt tacaagatat ctctaaatta tggcgtcttg acttcggtga ttcaatcgta
     7021 gcagctgttg aagacgctgg gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa
     7081 tcaatgcgtt atttcaactc aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa
     7141 aatattacgc aaaaagtatt agatttcatc gaacataatc cagaaaaatt acgattccat
     7201 gaccaagatg cattaaatgc tatcttacat gaccgttggt taccacttca tccgcgttgg
     7261 aatgcacaag gctatatcat ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt
     7321 gaatacgaag aaactcgcaa caatccttac attatccatt tttcaggaca tgtgaaaccg
     7381 tggagcaagg attttgaagg gccaacgaag aaatattacg aaaaatatgc agggatgacg
     7441 gctttccgtt gtgtagctaa attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa
     7501 acagatgtag ttgttaaata atagaagaca acaactgaag agggggagta ggaatggaaa
     7561 ttacaatgtc taaaaatgca gtagagacgt taattgaaaa ggttggggaa aatacaaaaa
     7621 tcgcactcgc gcttatcaat gattccgatc catttctaag ggacaaaggt gcttttgcaa
     7681 aaggcagctt ttttcaaatc attccttttg tttcggaatt tggagaatat gcgactaaaa
     7741 tcgagcatcc attattggac atctatacat ctaaattaga gcaaaattat ttcggtaaac
     7801 gattgaacat ggacttcaac aaacagcttg acagcttttc attagaaaat gaaatcgcag
     7861 tactcgatta taatatcaaa ttaaagaact gcttcttcag ctaatagttt cgagaaagtc
     7921 caaaaaggag gtatacattg agatactact ttgtggatga agaaaagaat gtaatagaaa
     7981 cagatgaaaa aaaatataat tggctcgtac ttgatagtgc aaagcccgaa gagattgagc
     8041 aagcaatcga agaattcgag cttcctgatg atattttcgt aggaaccgaa tatccggaag
     8101 aagtttctcg gatggagcgc ctttatgaga cgaaactaga gcatccattt tctttggtag
     8161 tgattaatct agatcagtca gataatcgta tcgaaaaaaa attaacgcca atatcttttg
     8221 tactttccga taatctcttg attacttgta tcgatagaaa aaccgaattt gtggatcggc
     8281 tgctgacaaa gcatggaaat catttaaact cgtttgaaaa gatcatcacg tatacattat
     8341 tagatattta cacccattac gtgaaagaac taagagagat gaaaaagcga attgacgctt
     8401 tggataaagc agctcgtaaa acaacggaaa atgaagaact gtataaacag gcagatcttg
     8461 aaagagacat cgtatatatc gatcatacct taagagatca acgggaaaca atggatcaat
     8521 tatggaattc tgaaactttc atcaaacgtt tagacgatga acagctactc tatgatgtcc
     8581 atttgagaca gcgacaaaca gaaaaaatga tcgagatcta tcgagattta ttagagagta
     8641 ttggtgatct attcaacggg atgatggaca ataatctaaa tcatatcatg aaatatctag
     8701 attcagctgc attaatcatt tccgttccgg cgttgttcgc agggatttgg ggaatgaata
     8761 caggaggatt accgggtaaa agttctgctc taggctttat actcgtagtc tttggctctt
     8821 tgatagcagc agtagtttta ggttaccatt tataccggaa agattataca aattaaagaa
     8881 tctatttaaa acaggtatca aacaaagaaa tttgttttgg caatacaatt taaaaactag
     8941 gaggaataca gcaatgacag aaccaaaatt aatcgacccg cgaaacttgt accatacgga
     9001 gaaatttcct aaacaagatc aggatacacc agctttacag cagaatatga ttcctgttcc
     9061 tgattgtgga gaagaatcct atgaaggcaa taatcaacta gaaaaccgcc gtgtactaat
     9121 cactggtgga gattcaggga tcggtcgtgc agcagcgatt gcatttgcta gagaaggggc
     9181 agatatcgct cttcaattct tcccaggaga agaaaaagat gcagaggaag tagcaaaata
     9241 cgtgaaagtt gcaggacgta agattgtctt actacctttt gatcttcgtg acgaacaagc
     9301 acctaaagaa atcatagata aagccgtgag tgaacttggc gggctagata cgatggtact
     9361 aaacgcagga cagcaaattt cttgtcagtc tattgctgag ttaccacttg agcaagtcaa
     9421 agacacattt atgataaaca tcatcgctat gtttgcttta gtgaaagaag ctgttccgca
     9481 tatcccagca ggaggagcaa tcgtaacaac aacttctgtt caagcattca atccaagcga
     9541 acatttatta gattacgcag caacaaaagc ttcaatcgct aactttacga tcggtttagc
     9601 aaaacagctt gcacctaaag gaatccgtgt aaatggtgta gcacctggtc caatctggac
     9661 accattacaa ctagacgaag gacaaccttc tgattcgatc cctgaatttg gtcagcaaag
     9721 tttactagaa cgtgcaggtc agccaggaga attagcacca gtttatgttt tcttagcatc
     9781 gaataaagca agttatgtta cagcccaaat ttacggagta actggtggag aagcgatcaa
     9841 cttataagaa gttgatcgtt tcacccctat gaggaggtgc gaaaatgaat aaaggtgtaa
     9901 aaacgatcgg agtgatcgga acattacttt tgctatctgt gcttttgttt gcgatactat
     9961 taagtgcaac ctatccattg ccttttcagc tagagaagtt tcgattcttt tccatcacta
    10021 attcatacgt gcaacaatat gtattttggc ttgccgttgc atttgctatt ttgacaatta
    10081 tcacgttact tgttttcctg ttttatccaa aaacaatcgg aaactttcta ctgaaacatg
    10141 gtgatgggga gttgacgttg gataaaaaag caattgaagg aatggttcgt tctcacttgc
    10201 atgaagatga attcatccat tcaccaaaag taaatgtcaa agcaacgaaa aacaagatcg
    10261 ccgtcaatgt aaaaggggag ttgaaacgaa cttcagcact cattggtaaa acaggaacat
    10321 tgatgaaaga aatcgaaaat gaagtacaac acatattggg aacaaaagag ccagtgaaag
    10381 tatcggtgaa atacacaggc tttgaagaac cagctaaacg aagcaatgac cgcaaacgag
    10441 tagaataggg ggggaccaaa aatgaaagaa ctattttcga catacaagct ccctatcatc
    10501 tttggggtac ttggattgat attagccgtt ttatggatca ccgtgggctt tttcaagacc
    10561 ttattgatct tgatcatggc agcgatcggc gtcgctatcg gtttttatct gaaacaaacg
    10621 aaaatcttag atcactattt taaatcttag gaggaaacat ccatgaataa caataacaaa
    10681 aataataaca ataaaatgaa caaccaaaaa ccagtgtctg cacatccaga cccaacgaca
    10741 ccaaaccaat caaatggtgt gaacgatgaa aagaacaaaa cagcaccagt atctgcacat
    10801 ccagatccag tagtccctaa cgttcaacaa ggagtagaag agaagaaaca tgatgcagaa
    10861 aagcatgcac ctcatcatcc aggaactcca gaatctaaag ttccagaaca acatgatgca
    10921 atcgatcctt ctaaacctgt ggaagagcaa aaacatcctt ctgaccatgc gaaagcacaa
    10981 gaaaaactta gttctgacca cacaaacgga caaggaaaac ttggttctga tcatacaaat
    11041 aaccaaggaa agcatgattc tgaacaggaa gattcaatgc gcggtgagct gaattatgaa
    11101 gataaagttg tgcaaaaaat catcggaatc gcaattgaac aagtagacgg tttattatct
    11161 gcaaacggtg gtttcttctc taatgtggca ggaaaacttg tgaatacaga taatgtaacg
    11221 gctgggatcg aaacagaagt cggtaaaaaa caagtagcag ttgatatgga tgtcattgtg
    11281 gaatatggca aagatatcga aaaaatcttt gaagaaatgc aagaagtaat cggcaaagaa
    11341 gtaaaaaata tgacacattt agaagtgatc gaagtcaacg ctaacgtagt ggacatcaaa
    11401 acaaaagaag aatttgaaaa agatcaagaa acggtgcaag acaaagtaac tgacgcagcg
    11461 aaaaaaaccg gtgaatttgc ttcgaatcaa acagataaag taaaatcagc agctggaagc
    11521 ggcgcacaaa aagtaaaaga aaatacagaa ccacgggttc agtaataagg aagtaaaaca
    11581 ttaggaggaa cgaaacatgg gatttatttg gtcacttatc gtcggaggaa ttatcggagc
    11641 aattgcagga gcaatcacga ataaaggttc ttcgatgggg attattgcaa atgtcgtagc
    11701 aggtttagtt ggatcagcac ttggtcaagc attattaggt tcttggggac caagtattgc
    11761 aggaatggca atcgtgccat cattgattgg tgccatcatt ttagtactaa tcgtatcatt
    11821 ctttgctcga aaactgtaaa aagactttta aaaagaggtc gtgaaaaagc tgttcttcat
    11881 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcatttg gttgggcata
    11941 ttatcgaaga tgcaagcttt tgaacactgt ttatacggaa taagaggctg tgacaagact
    12001 tttgtcacag cctcttattt atgcgggcaa attcccaatt agatttttaa aagtttttcc
    12061 ttaaatgtgt ctttattgat acagagaagc ttctttaata aaacaatgcc tccctaaatt
    12121 ttcttgagat aggaaaggtg aacatacaaa ataatacgac cactttgaaa acccagatga
    12181 tccacaaatg gatcgtatga tactgatgaa gtaaaaagca atggatcaga aactcaaaga
    12241 gattgaaaaa gacaaggaag aaataatatc tcttttttac tcttgtctgt tttagccaat
    12301 aatagctcgt aaagtaatct agacaaacaa atagaagtaa acaaagtttc gtaagagcag
    12361 caatcgtatc atgttgctct gctagacgat tgacgagcag gaaaaatgtt ggtaatggaa
    12421 tatagatcac gagtaatgaa agaaaaaagt aaacaataaa tggcatacta ttcctcctaa
    12481 ttgtgtgagt tcgccctcat tttaaaataa cgatatttgt ttgtgaagct ttttcgtgtc
    12541 gtaacaaatg ttatctaatg tatttttaaa taaataatca ttattatcaa aataatg
//
LOCUS       DARPZJ010000068        12060 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.071, whole genome shotgun sequence.
ACCESSION   DARPZJ010000068 DARPZJ010000000
VERSION     DARPZJ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.071"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..174)
                     /locus_tag="SLE23_002361"
     CDS             complement(<1..174)
                     /locus_tag="SLE23_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8469233.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIW"
     gene            complement(285..455)
                     /locus_tag="SLE23_002362"
                     /pseudo
     CDS             complement(285..455)
                     /locus_tag="SLE23_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(629..2704)
                     /locus_tag="SLE23_002363"
     CDS             complement(629..2704)
                     /locus_tag="SLE23_002363"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEI8469234.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2706..3623)
                     /gene="glyQ"
                     /locus_tag="SLE23_002364"
     CDS             complement(2706..3623)
                     /gene="glyQ"
                     /locus_tag="SLE23_002364"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEI8469235.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(4007..4819)
                     /gene="recO"
                     /locus_tag="SLE23_002365"
     CDS             complement(4007..4819)
                     /gene="recO"
                     /locus_tag="SLE23_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEI8469236.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4962..5861)
                     /gene="era"
                     /locus_tag="SLE23_002366"
     CDS             complement(4962..5861)
                     /gene="era"
                     /locus_tag="SLE23_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEI8469237.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5876..6271)
                     /locus_tag="SLE23_002367"
     CDS             complement(5876..6271)
                     /locus_tag="SLE23_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HEI8469238.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(6255..6731)
                     /gene="ybeY"
                     /locus_tag="SLE23_002368"
     CDS             complement(6255..6731)
                     /gene="ybeY"
                     /locus_tag="SLE23_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEI8469239.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6748..8940)
                     /locus_tag="SLE23_002369"
     CDS             complement(6748..8940)
                     /locus_tag="SLE23_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HEI8469240.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8964..9935)
                     /locus_tag="SLE23_002370"
     CDS             complement(8964..9935)
                     /locus_tag="SLE23_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEI8469241.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10640..12019
                     /gene="brnQ"
                     /locus_tag="SLE23_002371"
     CDS             10640..12019
                     /gene="brnQ"
                     /locus_tag="SLE23_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEI8469242.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3261 a         2504 c         2202 g         4093 t
ORIGIN      
        1 ccatataaca caagcaataa tcactgtatc gcgttgcttc agttgatcag tatttcttcg
       61 gtttttaatc ttatctggta cacaattgtg gtatatgtta gaaacagttc tcataatttc
      121 cttgaatgtt ataaaagtat ctgtataatg ttcagtatat tttgatgaac gcatatgtag
      181 tcctcatttc ttgggagttt tgagactact atatgcgttt ttttgttgat ttaccaacat
      241 gtttagacat tttcctctaa gaaaaaatta actagcacca cgggttgttg ataatattct
      301 aaggctgatt ttccttgctt gaagaacaga tatactttat ggatcgtttg tcttgaacga
      361 ttcaagcaat gggcagtttt agcaacagat tgattcattt tgaaataaga ctctattatt
      421 acaagttcat ccgttgtaag atgggtatag gtcatttgta ctcactcctt ataattcttt
      481 ggtcggaact attttgagtg tagcacaaat gactttttta gttgtctagc ttaattttac
      541 aatcggcgag ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct
      601 gttctctggt ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta
      661 gtgacaaagc catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg
      721 gttcttctgc catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta
      781 caagctgatc ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta
      841 ctgctttgtg cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt
      901 gtttttcaag ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg
      961 gtttgaagtc ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg
     1021 tcagatcttt ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg
     1081 ttgtcaataa ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg
     1141 acaagccaat gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca
     1201 gaacagacaa aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt
     1261 gacggcgcaa agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag
     1321 aaaagatact atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta
     1381 aatctccttc actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt
     1441 tctcgccttt aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc
     1501 ctaccatgtt ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca
     1561 attcttcctc agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt
     1621 gcattttctc atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa
     1681 cgtattggtc gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac
     1741 gagcagtcaa tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat
     1801 tacgagcaga aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac
     1861 gttgatgttc tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt
     1921 cgaagtcgcc agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat
     1981 cttcatctag atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga
     2041 tcatttcttt tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt
     2101 attcttttgc atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc
     2161 tgtctgtttt gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga
     2221 tccagtgaat aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga
     2281 aagtgaggct tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt
     2341 gagtgtattt cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat
     2401 ctgtcgtcag accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg
     2461 cgtccaaagc aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt
     2521 ctggaatgtt tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat
     2581 cataagtcaa ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc
     2641 ttggtgtgac aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg
     2701 ccatcttatt cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg
     2761 aatcctaatt tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg
     2821 atacgggaaa gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa
     2881 ttgaatgtat ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg
     2941 atacagcgtt tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg
     3001 cttacttcaa aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat
     3061 ttcacgccat cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca
     3121 agacgttcta gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact
     3181 tgctggaagt acgtgaattg tgtaatctcc atcccatcaa gccatacttc ccaacccaca
     3241 ccggcacaac ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct
     3301 aatggatcaa ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt
     3361 gaaggtttca ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca
     3421 taacgcccgt cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt
     3481 ccgattgccc gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa
     3541 gcttgcatca gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct
     3601 tggacggtca attttttact catctgtttt gcccctttca atttttaagc gttgctgtca
     3661 ataagaatac aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac
     3721 gaataatttc gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta
     3781 ctcgcaagtg cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa
     3841 accacgtgtt ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt
     3901 atataataga tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt
     3961 ccctgtattt gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt
     4021 caggtatctc tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact
     4081 tcatttgatc aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact
     4141 ggtcaatgag gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct
     4201 tatcataaga aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat
     4261 aacggtgttc gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat
     4321 agtcaaattt tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc
     4381 cgaagcgttg cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt
     4441 ggtccatccg ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat
     4501 cttcgattgc tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat
     4561 cttcttggat gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt
     4621 cacttagaaa attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg
     4681 gctgattttg ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa
     4741 agattttgac taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg
     4801 attctgcaag ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg
     4861 ccgatccaga ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat
     4921 ccagtttatt tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg
     4981 tagccgaagt cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa
     5041 agttctagaa atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct
     5101 acttgcttca gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca
     5161 acgatgatcg tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca
     5221 acgactgcga cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc
     5281 aattcagaaa cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt
     5341 gggccctctg gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct
     5401 gtagcagaga tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt
     5461 cccagcaact cgtctggatg gatcttatcg attttattga taatcagata aactggagaa
     5521 tgcacgtttt ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca
     5581 ctgatcataa ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata
     5641 aaatctccta gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga
     5701 gcttctggtg tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc
     5761 ataatggcaa ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg
     5821 cggccgacga ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat
     5881 taaacaacaa atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac
     5941 aagcggtcac taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa
     6001 aatgaaaatc cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta
     6061 tccaaacgag aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa
     6121 tcacgcccat aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt
     6181 cctcaaaaac ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt
     6241 ttttctctac gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca
     6301 aacatttctt tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca
     6361 tgtaccgcta aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca
     6421 gcagcacgtt caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca
     6481 tcttcaaaaa tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg
     6541 tctgtcggtg catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc
     6601 atgaaagtaa cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc
     6661 agcaagtcat cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag
     6721 gtaatatcca ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac
     6781 ttctgttttc attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat
     6841 caatgatttt tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc
     6901 atcggaaata cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg
     6961 atgatccatt gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc
     7021 acgactttgc ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg
     7081 ttctttcgct ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat
     7141 atcgatcacc atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg
     7201 tccaaagata atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc
     7261 tgaaggcaag ttctcaacga aaaagctagc gtgtttgatc ttgccgatat catgataata
     7321 gcaagctact cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag
     7381 attagctacc atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa
     7441 taaaggatga tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat
     7501 caattcaata tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa
     7561 cccgcagaca agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat
     7621 caaaatgaca tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg
     7681 ttctgagatc cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat
     7741 caagataatc gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac
     7801 tgcttggaaa ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag
     7861 tggtgcaaaa gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa
     7921 ttggaaaaat ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta
     7981 ttttgttctt tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg
     8041 aagcaaaaca gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag
     8101 tcctagtaat tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat
     8161 gatttctcct tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc
     8221 ttctgtcttt ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg
     8281 aatcatttgt tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg
     8341 tttaaaagct tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt
     8401 cagactctca tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata
     8461 aaaattgttc ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt
     8521 tttcttcagc gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt
     8581 tgccttatca atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa
     8641 ttcaaatagt tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta
     8701 ttctggagtg actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc
     8761 gatcgttttg ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc
     8821 cttttgtttg acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag
     8881 gaaaggcaat gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat
     8941 gtgcttatcc tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg
     9001 atgatttcgg caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg
     9061 attttcttga tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga
     9121 ggcagatcaa tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt
     9181 gtcaggaaca ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat
     9241 gcatcatcca atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt
     9301 tccatcaatc ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga
     9361 cgcagataag gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct
     9421 gcttccacag caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg
     9481 attgctaata ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg
     9541 atatcatgtt tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata
     9601 ggttttccat tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat
     9661 gtgccttttt gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct
     9721 cgtttgatca attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt
     9781 tcgccaatga tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca
     9841 atcagtttta tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc
     9901 aatctaatct ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat
     9961 tcattctttc ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct
    10021 aaaagagttg cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct
    10081 aaaggtctcg tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa
    10141 gtattccgtc taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa
    10201 caaaatattt gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa
    10261 taaatataca gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga
    10321 gtcatgtaag tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt
    10381 cgaaaacgta gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa
    10441 agcgtccgtg aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta
    10501 gagccctttt cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg
    10561 aatctgatat tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata
    10621 attattggag gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat
    10681 ggtcagttca cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca
    10741 cttaggtcaa atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg
    10801 cgctcttttc ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta
    10861 tgacttagct aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt
    10921 aacgatcgga ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc
    10981 taaacccttt ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt
    11041 ctttttactt gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa
    11101 gtatttaaac tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca
    11161 acccatgggg aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa
    11221 tggcgtttta gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac
    11281 ttttgtccat gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc
    11341 aaaagctggt agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct
    11401 cggtgcgatg agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca
    11461 gatcactaat ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt
    11521 aggtgtcttc actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact
    11581 gttccctaaa gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt
    11641 tgcgaatgcc ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta
    11701 tccattgtca cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc
    11761 atttgtctat caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc
    11821 aaattcgcct gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca
    11881 tcattatgtt ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta
    11941 cgctggcagc ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag
    12001 tgagttacca gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga
//
LOCUS       DARPZJ010000069        11886 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.072, whole genome shotgun sequence.
ACCESSION   DARPZJ010000069 DARPZJ010000000
VERSION     DARPZJ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.072"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(90..965)
                     /locus_tag="SLE23_002372"
     CDS             complement(90..965)
                     /locus_tag="SLE23_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEI8469243.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(1047..1838)
                     /gene="codY"
                     /locus_tag="SLE23_002373"
     CDS             complement(1047..1838)
                     /gene="codY"
                     /locus_tag="SLE23_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEI8469244.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(1856..3256)
                     /gene="hslU"
                     /locus_tag="SLE23_002374"
     CDS             complement(1856..3256)
                     /gene="hslU"
                     /locus_tag="SLE23_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HEI8469245.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(3270..3818)
                     /gene="hslV"
                     /locus_tag="SLE23_002375"
     CDS             complement(3270..3818)
                     /gene="hslV"
                     /locus_tag="SLE23_002375"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HEI8469246.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(3855..4760)
                     /gene="xerC"
                     /locus_tag="SLE23_002376"
     CDS             complement(3855..4760)
                     /gene="xerC"
                     /locus_tag="SLE23_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HEI8469247.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(4958..6334)
                     /gene="trmFO"
                     /locus_tag="SLE23_002377"
     CDS             complement(4958..6334)
                     /gene="trmFO"
                     /locus_tag="SLE23_002377"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HEI8469248.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(6303..8381)
                     /gene="topA"
                     /locus_tag="SLE23_002378"
     CDS             complement(6303..8381)
                     /gene="topA"
                     /locus_tag="SLE23_002378"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEI8469249.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(8503..9360)
                     /gene="dprA"
                     /locus_tag="SLE23_002379"
     CDS             complement(8503..9360)
                     /gene="dprA"
                     /locus_tag="SLE23_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEI8469250.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(9416..10183)
                     /locus_tag="SLE23_002380"
     CDS             complement(9416..10183)
                     /locus_tag="SLE23_002380"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEI8469251.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(10176..11036)
                     /gene="ylqF"
                     /locus_tag="SLE23_002381"
     CDS             complement(10176..11036)
                     /gene="ylqF"
                     /locus_tag="SLE23_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEI8469252.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            11296..11694
                     /locus_tag="SLE23_002382"
     CDS             11296..11694
                     /locus_tag="SLE23_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEI8469253.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         3135 a         2582 c         2081 g         4088 t
ORIGIN      
        1 cgatgtcaca ctcccttatt acttacagga tagctttttt acacaccttg gtaaacggtg
       61 ttccctgcta acttctcggt cacaacctct tacttcactg tgatggaata ttttgtcttg
      121 aagatttcat gggcacctag ttgattgatc cctacttttt ccatcaagtt tccactactg
      181 ttcaccgtgt cagcgattcc gcaccacggt tcgatacaaa cgaaaggcgc ttcttttgga
      241 taaggagacc agatccctac ataaggcata tctttatagc ttaaagttac gctatgggaa
      301 gatttttcac ttcgaatggc gtacgcattt agaccccttg tttcaaaaac caaggcatct
      361 tgctcaaaaa gttcacgatt caaagccaga ttcgtatttg tctgacctaa cgtcttttga
      421 tccatatcga tgaatgggcc tttcaatggt aggcgtaatc ttgatttcaa tggagaaaat
      481 gccagataga aatcttcaaa tgacaatcct tcttcaagag gtacattgaa agcaggatgt
      541 ccaccgatag aaaagaacat ttctttttca ccggtatttg ccacttgata atgaaccgtg
      601 atgccgtctc ctcctaattc atagctgatc actaattcaa aatcaaatgg atacttttct
      661 aatgtctccg gcgtactcct taagatgaaa ctagccattt cttgtccatg ttcaatgact
      721 tcaaaatcca tatcccgagc aaatccgtgt tgccccattt gatatgtttt cccttgataa
      781 acatactgat catcttttaa acgtccaaca aaagggaata aaaccggtgc atgtctgccc
      841 caatacgctg gatcaccttg ccagatatac tctaaaccat gttcttttga tttcagactg
      901 atcaattccg caccgtgttc agcgatttcg gcgatcagct ggtcattttg aataataaca
      961 gtcattgcca ttcctccaac ttcgacttac tttttaaaat gggaaggctg gaacaaacat
     1021 ttctatctgc cccagtcccc ttacttctaa taactgtgtt ttgctaactc gtctttaaaa
     1081 cgggaattca atacttttaa ataagttccc ttcatgccta acgaacgaga ttcaatgatt
     1141 ccagctgatt ccaattttcg taaagcattg acgatcacag aacgagtgat gccgatacta
     1201 tcggcaatat tagaagcagt cagacgacct tcatctccat ccaatgcttc aaagatagct
     1261 tgtacagcct tcaattcgct ataagataat gtgttgattg ccatttggac agccgttgca
     1321 ctccgtacat ctgcttcgat gcttcgagac ttctgataaa ggatctgcat accgacaacc
     1381 gtagctccat attctgctaa gactagatcg tcatctgcaa acgattgttc catacgagat
     1441 aagataatcg tacccaaacg ttcgccagct ccaaagatcg gaacgacagt cgtcagacca
     1501 aatggatatt tctctcttga ctctaccgga aatgcagtaa tatcactagt aattgggata
     1561 ttagcttcag ttttcatcaa ctgtgccact gtatcagtat aagattcagg aaattgtttc
     1621 tcaacaaaca ttgttttgat tcgttcattg ttcacatcgt gacgttcatt ataacctagt
     1681 aatactccgt cacttcctat gatataggtg ttgctgtcaa gaataccacc tagtgtgaca
     1741 gccattttat cgtaaggcaa atctgcttgc atgtcaaaag tattcttttg ctgcaaaagt
     1801 gtgtttatct tgcgggtttt cgttagcaag tctgtcattg tcgtcctccg attttttata
     1861 aaatatagcg acttaaatct tcatttgccg caattgagcc aagtttgtca tccacatatg
     1921 cttctgtgat cgttatttct cccatttgca tatctggtgc ttcaaataat agatcttcta
     1981 gtagtttttc caaaatggta tgcagtctgc gtgcgccgat attatctgtg tcacggttga
     2041 catcgaaagc gatttgagcg atccgttcaa ttgcttcttt tgtaaacgta actgacacat
     2101 tttctgtacc gatcaacgcg acgtattgtt ttactaaagc attatttggt tcggtcagaa
     2161 tcttcacaaa atcttcagct gtcaaatcat ctaattctac ccgtatcggg aagcgtcctt
     2221 gaagttctgg aattagatca cttggtttag acaaatggaa agctcctgaa gcaatgaata
     2281 ggacgtgatc tgtttggatg atcccgtatt ttgtgtttac ttgtgaacct tcgacaattg
     2341 gcaatatgtc tctttggacg ccttctctgg atacttctcc agattgctgt gatttagaag
     2401 tgatcttatc gatttcatcg ataaaaataa ttccactttc ttccgctaat ttgattgcct
     2461 cactatggat atcagcatcc ttgactaatt ttgctgattc ttccttgatc aataactcta
     2521 aagcttcttt gactgttacc gtccgttcca cttttttctt cggtgtcaaa gcacctagag
     2581 tttcatttag gtcgatcccc atttgctcca atccattgtt catcattggt gcaggtttct
     2641 tttggtcttc aacttcaatg gttacttcac gactatccag taaacccttt tgtagttgtt
     2701 ccaagactgt acggcgattg attcgaatat cttctgtcac ttcttcttgc ggttcagcgg
     2761 tattttgctg actagcatta aaaagattca tcatttgttc aaattgatta gtggattgtt
     2821 tctgttcttt tttgatacca ggtaccaaga tttttaccaa acgtttttct gcattttttt
     2881 tagcacttgt gtatacacgg ctgtactgct ctttttctac gatttggatc gcattttcta
     2941 ctaaatcccg aaccattgat tctacatctc ttccgacata accgacttca gtaaattttg
     3001 ttgcttcgac tttgacaaat ggtgcattga cgatttttgc caaacgtcgt gcgatttctg
     3061 ttttaccgac ccctgtaggt ccgatcatca gcatattttt tggtgtaata tcttgttgca
     3121 ttttttcatc taactgcaaa cggcgatagc ggttacgcaa agcaacggca acagattttt
     3181 ttgctgcgtg ctgtcctacg atatattcat ctaattcact tacgatttgt cttggtgttt
     3241 gttttaattc atacatatct actcacctct tacagttctt ctacgataat attatgatta
     3301 gtaaagatac agatatctgc ggcaatattt aacgcatttt ctgcaatttc tttcgcactc
     3361 atgtcgtttt gagcatagtt tttcattgct cgggctgcag ccaacgcaaa attccctcct
     3421 gatccgatag ctaagatacc atcatctggt gtgataactt ctcctgtacc tgaaacaaga
     3481 agcatttctt tatcattcat tacgatcagc atcgcttcaa gtttttgcat agattgctgt
     3541 gtccgccatt cttgagctaa ttcgacagct gcgcgttgta gattcccgtt atattcgttt
     3601 agtttgcctt caaatttttc ttctaaagta aacgcatctg caacacttcc ggcgaaacct
     3661 acaacaactt ctccattgta gatacgtcgt actttctttg cagtgccttt catgacaaca
     3721 gattcaccca ttgttacttg gccatctcca gccatagcaa atttcccgtc tttttcgacg
     3781 gcacagatag tggttgaatg aaatggtgat tcgaccatgt ttgtttcctc ctaaatttgt
     3841 tcttttcctt atttttacgc tcttggatgg aaagaacgat agtttttttg taaactttct
     3901 tttgttacat gggcatagat ctgggtagtc gataaattgg catgtcctag caattcttgg
     3961 actgtccgca aatctgcccc attatttaat aaatgagtag caaatgtatg gcgcagcatg
     4021 tgaggatgga tatcactatc caaactgctt tttttgatca tttgattcaa gacatattca
     4081 attccagtag gcgtgattgg ttttccatga tgattcacaa aaacgatatc atgctcttcg
     4141 tgatattttg tcatcaatac ctggcggcct tccctgaaat attcttgcag agcatcttga
     4201 gcaaaagaac ctagaggagc atatctctct ttgttccctt taccatggat caacatgacc
     4261 tctgaatcaa aatcaatgtc tgataccgac aaactgctac actcacttaa acggatgcct
     4321 gacccgtaaa ggacttccag taaagcgcgg ttcctcaaat ccaaaggact atctcctgct
     4381 acgctgtcaa aaagtgcttg catttcattt tcataaaaaa aacgtggcag tctcaaattt
     4441 ttctttttga gatgaacgta agaaaatgga ttttctttta tcacttcttc tttgagaaga
     4501 tactgataaa acgaacgtag gctggctatc ttgcgactga tagaatttct gctatagcta
     4561 ggacgatgat cagctaatgc actcaaatag acacgaaccg taaaatattc cgccttcagc
     4621 agatcagcgt ctccagattc ctccaaaaaa tgtttgaaat ggagaatgtc ttcttcatat
     4681 gcttctttcg ttttttctga atatcctctt tcgacaatca aataacgcaa aaatttttgt
     4741 tcccacgtgg cttctgtcat tttctcacct tccttttgtc ccagagaata atttagcaca
     4801 gcgtttataa aaagacaaat aaattgtcag aatttaacca atatttctaa gtttgttcac
     4861 aattggcgca attcctcaca ttttgtttga gaaattctta agaaaaacgc aagaaaaaga
     4921 gcgagactat ccgtctcacc ctcttcatgg agtttcctta ctcatttggg attgcagttt
     4981 tttctaattc tgtttttatt gcctcattag cttttaaagc tcgttgtgca attgcttcat
     5041 atcttgcttt tttgtctcga atgcgctctg gcagttcagg aaacagacca tagttggcat
     5101 tcatcggttg gaaatgtttt ccttccgcat gagtaatgta gtaagccata cttccaatag
     5161 ctgtttcttg tggaaactcg actggttcca tttcttttgc taagcgtgcg gcgttgattc
     5221 cagcaagtag tccgctcgct gcactttcaa catagccttc tacaccagtc atctgacctg
     5281 caaagaacag atcttcgcgt ttcgttgatt ggtaagtcgg tttcagcaat tctggcgaat
     5341 tcataaagct gtttcggtgc atcacaccat agcgaacgaa ttcagcattt tctaacccag
     5401 gaatcatccg gaaaacacgt ttttgctcgc cccatttcaa gtgagtctga aagcccacga
     5461 tgttgtataa agaagctgca gcattgtctt gacgcagctg gataacagca taaggacgtt
     5521 tgccagtttt aggatcttcc aatccaactg gtttcatagg tccgaaaagc atcgttttga
     5581 atcctcgctg tgccattact tcaattggca tacatccttc aaaatatttt tctttctcaa
     5641 aagatttaag ttctgccact tcggcattga ttagtgcctc atggaaagct ttgaattcct
     5701 cttctgtcat cggacagttc aagtaagctg cttctccttt gtcatagcgg gacttcaaat
     5761 atactttatc catatcgatc gtagctttgt ctacgattgg tgcagctgca tcatagaaat
     5821 aaaaaccatc tgaaccattg aatgctttga tgctttctgc taatggatga gaagtcaaag
     5881 gtcctgttgc tactacggtg attccttccg gtatttcagt aatttcttcg tttatcactg
     5941 ttactaatgg atgctctttg acttttcggg taattgtttc agaaaaagaa tcgcggtcaa
     6001 cagctaaggc accaccagct ggcactgctg tttcatctgc cgaagtgatt actaccgaat
     6061 tcaatcggcg catttcttct ttcaataacc ctactgcatt agccaaactg tttcctctta
     6121 atgaattgga acatactagt tcagcaaaat tacttgtgtg atgcgcctca gtcgatttga
     6181 ctggacgcat ttcatataaa cggacaggga ctcctgcttg tgcgatctgc caagcagctt
     6241 cacttccggc aagccctgct ccaacaacat ttaccatttt caatgaaaga acctcttttc
     6301 tattattttt ggatgtcttc ttcgtaatct ccatttacac agactacttg tttaccgcct
     6361 ttgactttct tctcgaccag atatccgtca cattttggac aatttctgcc cactggttta
     6421 tcccaagaag tgaattcaca ttctgggaaa cgggaacaac catagaatag tctgtttttc
     6481 ttagattttc gttcaatgac ttgtccttca tgacatactg ggcaagtcac accgatttct
     6541 tttacgattg gtttcgtatt ccgacaatca ggaaaattac tgcaagcata aaacttccca
     6601 tatttcccta attttatcac catcggatgt ccacagacat cacaatcgaa tcctgctggt
     6661 tcatctttga tttgaatttt ttcgattttt tcttccgcat tcgtcagttc tttttcaaac
     6721 ggtttataga aacgatcaac cactttgacc cacgcttccg tgccttcttc aattttatcc
     6781 aaatctcctt ccatttctgc tgtgaaatgg atatcgacga tttgagggaa gaattcacag
     6841 attaatgaat tgacaatttc tcctagttca gtcggctcaa atcttttttg tgtcaatttt
     6901 acatagtagc gtctttggat cgtatcaagt gttggtgcat aagtggaagg tcgccctacc
     6961 ccgttttctt ctagtgcacg aatcaacgta gcctcactaa aacgtgctgg tggttgagta
     7021 aaatgttgtt ttggttcaat atcaacagat tggactacat cgccttcttc aagttctgga
     7081 agaatatttt ctttctcttc tttgccgtca tctctacctt ccacatacac ttgcatgaat
     7141 cctttgaatt tgatttttga accgttcgca atgaagatga caccattttg ttctaatgtc
     7201 actttcattg tatctaaaat agctggtgtc atctgactag ccacaaaacg tgaccagatc
     7261 aatgtataaa gtttcaattg atctttatct aaatattgtt tgagttcatc tggtgtacga
     7321 agcacactcg ttggacgcac agcttcatgg gcatcttgtg cgccttgagc atttttgatc
     7381 tttcggtgat catgtctaga aaattctttt ccatacgtat cttcaataaa tgctgcggcc
     7441 tctgcttttg ctgtatcggc aatccgggta gaatcagtac gcatgtatgt aatcaagccg
     7501 actgttcctt gtttacccaa agtgattcct tcatataatt gctgtgctac catcatggtt
     7561 tttcttgttc gaaagtttaa cttacgggca gcttcttgtt gcaggctact tgtagtgaaa
     7621 ggattcgcag ggtttctttt gcgctctttc ttttctactt ttttaacttc gaagtctgtt
     7681 ccatcaattc tagcagtgac ttcttttaca ctttgtgcat ctggtaattt ctttttctta
     7741 ccgtcgattc cccagaaatt tgctttgaat ttcttgcgag cttttttaaa attaccgtcg
     7801 atgctccaat attcttctgg aacaaattct cggatctctt tttcacggtc aataataatt
     7861 tttaaagcga cagattggac acgtcctgca cttaaccctt tcttgacctt acgccagaga
     7921 ataggactga tcgaataacc aacgattctg tctaaggtac gacgagcttg ctgtgcatct
     7981 actaaatcta catcgatcgt tcttggttcc ttaaaagctg ctttgactgc gtcttttgtg
     8041 atttcattga agaccacccg atttttttct ttcagatcca acccaagtag gtacgctaaa
     8101 tgccaagcaa tcgcttctcc ttctctatcc gggtcacttg ccaagtaaac tttttgagct
     8161 ttttttgctg cggctttcag gcttttgatg acatcgcctt ttccgcgtat agaaatataa
     8221 tggggttcat aattgttttc aaaatcgata cccattttac ttttcggtaa atctcttata
     8281 tggccaacac tggccattac tttatagttt cgtccaagat atttctcaat tgtcttggct
     8341 tttgcaggtg attctacaat cactaaatat ttatacgcca ttactgaatg gactcctttc
     8401 cattgtcgtg ttcctactat taaaagagga ttcatacaaa tcgtagctaa tcatatccat
     8461 tcagaaaacg tttgtcaaga aaagcaaatg aaaagtatgg tgttattctt taaattctgc
     8521 caagatatct tcacccgaaa ccgtgcaaac tgcaccgtct tggatcaaat gatgacatcc
     8581 ggtagaatgt tctgttaaaa tatttcctgg aacagaaaaa actgttcttc caagatccaa
     8641 tgcttgctgt gctgttatca gagagccgct ttttttcttg gcttcaaaga cacatgttcc
     8701 tttagacaaa gctgcgataa tccgatttct cattggaaaa caatgctttt tcgggccgga
     8761 ttgaggagga tattcactca aaagaagatg atcatttgca atcacctctt gcaagtcacg
     8821 attttcagca ggatagactt gctctatccc tgttccaatg actgcgattg tccgtccacc
     8881 atgagagatt gctgcttggt gaccgtatgt atctatccct ttcgcgcagc cactgacgat
     8941 cacatatcca gcttctatca ctggttttag taaataataa actgtttttt tggctaaagc
     9001 agaagtgtgt cttccaccaa caacgcttaa catgttacaa gaaagtaaag atagatcacc
     9061 attataaaac agtacaattg gcggataggt caagtgaagc agctgagggg gatatttggg
     9121 atcaaagcaa gtgataaacg actgtttcga ttggattttg ccccagttag cgtgaatttc
     9181 ctgccaactt ttgcgaaaca gctcccggtg tttggttatt ttacctatct taatgatgtc
     9241 ttcaaatccg atttctttat aaggatactg catcatccag ttagcaagtg cccattttcc
     9301 ttgactactg attccttttg tataagcaag tttcaataaa ttttcttcta tttgatacat
     9361 cataaaaccg cctttcgtct ctctttctaa taagatacgt aaaagcggct gttttttatt
     9421 gtaaatattt ttttacaggt gcaaaacttt tacgatggat tggcgtaatt ccttgtcgtt
     9481 caagtccttc taagtgttcc tttgttccat aacctgcatt atgcgagaaa ccatatccag
     9541 gataaagcac gtcatattct ttcatcaatt ggtctcgata tactttagca atgatacttg
     9601 cagcagcaat cgacacagat cgtgcatccc ctttgattat tttttcctgc tgaataggca
     9661 aatccaaggt catcgcatcg atcaacaaat agcttggtac aatggacaat ttttctactg
     9721 cttggatcat cgctaattta cttgcttcat aaatattcac atcatcgatt gtctgctgat
     9781 caacgatccc gatcccgatt gccagggctt tttcttgaac ttgttgataa agaagttctc
     9841 gctttttctc tgataattgt ttggagtcat tcagccctaa tatgatctca tttttcggca
     9901 agataactgc agctgccacg acaggtccag ctaatggtcc tcttcctact tcatcaatgc
     9961 cggcaatcca ttggtgacct tgtgcgtacc cttgcttttc aaagcaaaac atttcttcat
    10021 atttttcctt aattaatgct tcctttttca atcgtcgttc aaaagaagcc agtgcttgct
    10081 gcacgccttt gcgtggatca tttcttaatg attctagtgt aggatcatct attctctgta
    10141 tgcttttcaa tcgttctttg atactttgga tggattcagt catcactttt ttgctccatt
    10201 tcttcgcaac gatccagtgt gtatcgtcca agttttcctt gacgaatatc atgcacgact
    10261 aattcgctgc cacgatcata gtcttcttta tacccacgtt ttgctgtaat atccatcagt
    10321 aattccggtg ccaatttttc ttcttgctcg attgataaac cataacgatc gctgattctt
    10381 cctgaataat atcgggcaaa aaagtctaat ccgtaaatcg ctaaatcatc taaatggaca
    10441 agctggtctt tgatcgcgcc tgtcagcgct agttttttgc cgatttcttc atcttcaaat
    10501 ttgggccata aaatccctgg tgtgtctaac aattccaact cattacctaa acgaagccac
    10561 tgctgacctt ttgttacgcc aggcttattt cctgtctgtg caattttctt gcctactagt
    10621 cgattcatca acgtagattt cccaacattt ggaataccta agaccattgc ccgaatagcg
    10681 cgaggcttga tcccccgagc agcatctctt gcccgttttt ctttcaatgc ttctttagcc
    10741 gcaggtacta gacctttaat tcctttactt tcttgtgccg tgatagctaa tgcaagatgg
    10801 ccttgtttac gaaaatattc ttgccacagc tttgtctgtt gtggatctgc cagatccgct
    10861 ttattcaata aaacaaggcg aggtttttgc tgaatgatct gatctagcat tggattacga
    10921 gaagataaag gtaatcgtgc gtctaccaat tcaaatacga tgtccacata tttcattttt
    10981 tcagaaactt ctcgtcgggc ttttgccata tgtcccggaa accattggat ggtcattgtt
    11041 ctctccattc ctttcatacc ggaatattcc ccggctttac ttgttttttt ctttttcaat
    11101 ataaattcac ttttttatta taaagaaatt ccatctatta gttaagtgaa agtgaaccag
    11161 tcctcattct atcacatctt cacttttttg atgatgcaaa tttttatttt ggtttctata
    11221 tatgaatcta aatttttgac agcgtttcct aaataagaga tgatagacga acaaaacaga
    11281 aaggagacga aacaaatgaa tagtatggtt tttgttaatt ttcctgttgc tgatgtcaat
    11341 cgttccgttg ctttttatga aaagctgggt tttaaaaaaa atgaagaatt ttctactgaa
    11401 gaagctggtt caatggtatg ggatgacact ttttggataa tgcttctctc tcatgatttt
    11461 tataaaaaat ttataaaaga taaagaaata gctgataata aaaaaacaag tggtgctttg
    11521 atttcgttta gtgttgaaaa tgcggatgaa gtaaaaaaat ttgctcaaat tgcaaaagaa
    11581 aatggtggta ctttccacga agtagatatg ggaatgcctg aagaagaaat gttttcatta
    11641 gaagtccaag atctagacgg aaatacatta gaacccgtat ggatgaagat gtaagcagat
    11701 aactaatctg acgtttttta taacaaaaaa acaaaggcgg atgatacgat aagtattctc
    11761 cgcctctatt ttttttattc gtacaatctc ttttttacag tttataaaag cagtcttctc
    11821 accctttttt taattgttag atgccagtgt atgtaaatca ccaatgtgtc atgacacatt
    11881 ggtgat
//
LOCUS       DARPZJ010000070        11770 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.073, whole genome shotgun sequence.
ACCESSION   DARPZJ010000070 DARPZJ010000000
VERSION     DARPZJ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.073"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            256..531
                     /locus_tag="SLE23_002383"
     CDS             256..531
                     /locus_tag="SLE23_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469254.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            544..2622
                     /locus_tag="SLE23_002384"
     CDS             544..2622
                     /locus_tag="SLE23_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HEI8469255.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2782..4668
                     /locus_tag="SLE23_002385"
     CDS             2782..4668
                     /locus_tag="SLE23_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEI8469256.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4680..5627
                     /locus_tag="SLE23_002386"
     CDS             4680..5627
                     /locus_tag="SLE23_002386"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEI8469257.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5647..6174
                     /locus_tag="SLE23_002387"
     CDS             5647..6174
                     /locus_tag="SLE23_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8469258.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6237..6890)
                     /locus_tag="SLE23_002388"
     CDS             complement(6237..6890)
                     /locus_tag="SLE23_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEI8469259.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7022..7864
                     /locus_tag="SLE23_002389"
     CDS             7022..7864
                     /locus_tag="SLE23_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEI8469260.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8022..8918
                     /locus_tag="SLE23_002390"
     CDS             8022..8918
                     /locus_tag="SLE23_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEI8469261.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8921..9634
                     /locus_tag="SLE23_002391"
     CDS             8921..9634
                     /locus_tag="SLE23_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEI8469262.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9654..10172
                     /gene="msrA"
                     /locus_tag="SLE23_002392"
     CDS             9654..10172
                     /gene="msrA"
                     /locus_tag="SLE23_002392"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8469263.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10169..10396
                     /locus_tag="SLE23_002393"
     CDS             10169..10396
                     /locus_tag="SLE23_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEI8469264.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10548..11099
                     /gene="lepB"
                     /locus_tag="SLE23_002394"
     CDS             10548..11099
                     /gene="lepB"
                     /locus_tag="SLE23_002394"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEI8469265.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11182..11682)
                     /locus_tag="SLE23_002395"
     CDS             complement(11182..11682)
                     /locus_tag="SLE23_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEI8469266.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
BASE COUNT         4104 a         1998 c         2401 g         3267 t
ORIGIN      
        1 ttttgtcgca gccccatttt tttgttgtga taaaagaaca agaaaggcag gaatgggaaa
       61 gtaaacatcc ttttgtcaga aacttttatc tttcttaagt tttacttgat atctgatact
      121 atttggaata gaatgaggcg ttgaaaaatt tatggaaatt tctaactagc aataaacgat
      181 gaaacaatga aatatttttc atccaaaaag aactttgcta taatgatgga agtttgtgta
      241 taggagatct ggaaaatgag agagagtttt gaacaacaaa aaaaactgtt gcatgatcgc
      301 tatggcgccc tttcgatgga tgaccgccgt caaatacttt gtaagttgcg taaaagaaat
      361 atattgatgt atcgtcagtt ggaacgtctg aaacatgatc tgcttcgttt ggagtcaaaa
      421 cgtgtacagt gtgaattaga ggggaaccaa acacaggttg aagtagtcga aaccaaaatt
      481 ttaaagaaaa aagaacaatt tttaaaaatg cttacacaaa ataaaaaata aaggggatgg
      541 acgatggaat ttgctgagtt agttattgta tttgcagtaa cgatcacctt atcgaacata
      601 gctagccgca ttttgccaat gattccagct ccactgatcc aaattttcct tggagtggta
      661 ttaggtctga cagagtgggg acaatcaatc gattttgaac ctgaattgtt cttagttatg
      721 attattgcac cattgttatt tagagaagga gaaaaagcag atatttcttc gattctcaaa
      781 aatttcggga caattttgtt cttggcattt ggaggagtca ttttgaccct tgtcggggta
      841 ggtgcgacgt tatcattcct gttgccaagt gtcccacttg ctgcctgctt tgcttttgga
      901 gcagcgttag gtccgacaga tgcggtagca gtcagttctc tttctggacg agtgaatatc
      961 cctaaaaagg cgatgcatat tttggaagga gaaggtcttt tgaatgatgc atctggtgtt
     1021 actgccttcc agtttgctct tggtgcgctg atcaccggat ctttttcagc agtaaacgcg
     1081 gggatgagtc tagtagtttc tagtattggg ggagctttga tcggcttttt gcttgtctgg
     1141 ttcaaacaaa aaataattca tttgatcgaa aaagcatcag cacaagatgt cacagggtat
     1201 ctgctgatcg aacttttgct tccttttcta gcctatgtat tggcagaggc atttgatgta
     1261 tctggaatca ttgctgcagt ggcagcaggt attctccaag cttctggttt taggaaaatc
     1321 tctgtgtttg atgcagaatt gtcgagcttg tcccacagta catggacaac tattgctttt
     1381 acactgaatg cattagtatt tatattttta ggaatcgaat tgacgcaagt gttctcgcca
     1441 gtatggggag acggtttata tccaaacggt cttttattag cgattatcgt attaatctct
     1501 gtcatgcttt ttgtgatcag attcatttct atcagtcttt tttatgtatt caaagatggc
     1561 agtaaaaagt tcaaaaaaca gttgaacgag atcttgatct taacatttgg cggtgtaaag
     1621 ggaacagtca gtttggctac gatttttatt ttgccatttt caatcaataa tatgatgttt
     1681 taccagcggt ctttgctttt gtttctgacg gcgggtgtca tcttagtgac tttggtcata
     1741 gggatcattg tcttgcctat gctgacggaa acagaggaag cgaaaagcac ggatttgaat
     1801 gctttgatga ttttagaaga ggtcgttgaa gttttgcgaa aagaaataaa ggaaattgat
     1861 cgtaatacaa aagaattttt agccactgaa gcagtgatag aaaattatca agaacggata
     1921 cgtgatctgt acttggaaga tttaaccgat gatgaaaagc aagaagtaca agaaatacaa
     1981 gcactgattt tgtcgatcga acgggatgga ttggatgaaa gttatcgttc gggcaagctt
     2041 tcttctaatg gttatcgttt ttactcccgt tttctttctc gattcgaaca ttctatcaca
     2101 agccagattt tgtcttttat cggcttttgg ttcattgttg tccgtaggtt aatgcgaatc
     2161 gttctccatc cgaaaatgtt ttggcaaaga agatatgctg atcgtcagac atttattagt
     2221 gatgaagata tccaagaaat cagagagaca tatcaaaaaa atactcagtt gattattgaa
     2281 agtttagata acttgactga tatttatgat gaaacgatgg ttcaattttt tatccagcaa
     2341 cgcaaacttg aaggaataaa aatgaactcg gggaatttga tttcttcgtg gatgatccag
     2401 caagatagtc tgtttacgaa aaaaatgcta agaggttatt atcttgaaag aaaaatcatt
     2461 gatgaatacg aagttgctga aaaaatcacg acgttttctg cgaacagcta tcgcaggaat
     2521 atcaatttgt tagaatctta tacgatgaac aaaccatctg ataacttttc tttccgattt
     2581 gcgtttcgag caaagtcaaa aaaaacgagt ccaataaaat aaaaaggtaa aaattttcaa
     2641 gttttataaa aaacaaaaca tatcagaaca ggatcgaatc ggtcctgttc tttttttgag
     2701 aacacaaaaa gaacaaatac caaaaaaatt ttcctgaagt tcactatttt tatgatacaa
     2761 tatccaagat aaggagggaa catgttgaaa gaattaaaag taactgacct caaaaaaact
     2821 tatggtgaaa aagatttgtt tgaccagatt tcttttttgg tccacgaaaa agaccgtatc
     2881 gggttgattg ggacgaacgg gacgggtaaa acaagtctct taaatattat tgccggtatc
     2941 gatagcagcg acggtgatcg gcaaacagtg ttttatccaa ctgattaccg tattggttat
     3001 ctttctcaag cagctgaatt ttccgatgaa ttaactgttc tccaagcagt ctttcaagga
     3061 aacagcccct tgatccaaac tgttcgagca tatgaggaag cattgatcga actaggggaa
     3121 aacggagaag accctgatgt gcaaaaacgt tatgctaaag cagaagaaca aatgaataaa
     3181 gaagatgctt ggactacaga taccaacgca aagattattt tgcaaaaatt aggaatcagt
     3241 gaattagata aaaaaatcag tactttatca ggtggtcaga aaaaacgagt tagtctggcg
     3301 caagtgttga ttgatgaacc cgatttacta ttactagacg aaccaacaaa ccatttagat
     3361 tatgaagcga tcgagtggtt ggaaaactat ttgaaacaat accgtggcgc actattgatg
     3421 gttacccacg atcgttattt tctagataga gtagcaaacc gaatcttcga actttcattt
     3481 ggaaaattat acgagtataa aggaaattat gaagcttacg tcttagaaaa agcagaacgt
     3541 gatcgtgtag aagtagaaca agaagaaaag cgcaagcggc tttataaaca ggaattagct
     3601 tggatgaggg ctggcgtaca ggcacgtggc accaagcagc aagcacggat caaccgtttc
     3661 gaagatctaa aggagaactt gtaccaagta aaccaagaag atgatttaga gctgaaccta
     3721 gcgacacaac gtttagggaa aaaagtactg gaaatcaaag atggcagtta ccgtataaat
     3781 gaccaaacac tgctagaaca tttagattta ttgattcaat ctcgggaaag actaggtatt
     3841 actggtaaaa atggtgcggg aaaatcgaca ttgcttaata ttctagctgg cagaattccc
     3901 ctggatagcg gtacaatgtc tatcggtgaa acggttcatc ttgcgtatta tacacaagaa
     3961 aatgaagaaa tggcaccaga taaacggatg attgcttact tacaagaagc tgctgaagaa
     4021 gcaaaaacag cagatggcag tcaaatcgga gtagcagaat tacttgaacg atttttattt
     4081 ccaagattta tgcatgggac actgataggc aaactttcag gcggagaaaa acgccggtta
     4141 tttttgttga aactgctgat tcagcaacct aatgttttat tattggatga accgaccaat
     4201 gatttggaca tagcaacatt gacgattttg gaagattatt ttagaagttt tccaggtgct
     4261 gtgatcactg tttcccatga ccgttatttc ttggacaagg tagcagataa gttattagta
     4321 ttccaaggaa acggaaaaca agaactttat tacggaaaca tgtccagtta tttactgaag
     4381 caaaaagaga cccagcagcc tgctgaaaaa gcgaaaccaa aaatacagag caaggaacct
     4441 gctgaaaaga agaaattatc ttacatggaa caaaaagaat gggaaacgat tgaagatgag
     4501 attgcagaac ttgaagaaaa aatctcattg ctccaagaag agatgaatca tcaaggagat
     4561 aatttcactc gattacaaga attgcaaaac gacgtatctg aaacagaagc acaacttgaa
     4621 gaaaaaatgg cacggtggga atacttgagt gaatgggtag aagattagga ggaaaaagga
     4681 tggaacaagc gtatcttgac ttaggaagaa aattgttgga agaagggcat cgtaaagaag
     4741 acagaacagg cacaggcaca ttaagcttat tcggatacca aatgcggttt gatctgcaaa
     4801 aagggtttcc tttgttaaca acgaaacgag taccttttgg attgatcaaa agcgaattgc
     4861 tttggttttt aaaaggagat acgaatatcc gctatctatt acaaaataaa aaccatattt
     4921 gggatgaatg ggcatttgaa cgctacatca aaagtccaga ctataatgga ccagatatga
     4981 ctgattttgg ccatagatgt ttgacagatc ctgaattcaa tgaagaatat aaaaagcaga
     5041 gcaagctttt ttgcgagaag atcctaaccg atgattcctt tgctgaaaca tacggcgatc
     5101 ttggacacat ctacggctat caatggcgtc actgggaaac aaaagacggt ggctttatcg
     5161 atcaaatcaa acaagtgatc gaagcaatca aaaagactcc tgattctaga agattgatcg
     5221 tttctgcatg gaatccggaa gatgttccta gcatggcttt gcctccttgt catacgatgt
     5281 ttcaatttta tgttcaagag ggacggctaa gctgccaatt gtatcaacgc agtggggatg
     5341 tgtttctagg cgttccgttc aacattgcaa gttatgcgtt gctgactcac ctaattgcac
     5401 atgaaacagg tttagcggtt ggcgaatttg ttcacacatt aggagatgct catctttata
     5461 tcaatcatat cgaacaaatg aaagaacaat tgagccgaga aatacgcgca tttccgactt
     5521 tagttttgaa tcaggaaaag cagtcagtat ttgattttga gatggaagat atccaattag
     5581 aaggatatga cccacatccg gcgatcaaag ctcctatcgc tgtttagaat cagaaaggat
     5641 gagaaaatgt tagctgcaat ttgggcacag gatgaaaacg gattgattgg aaaagaagac
     5701 cgtcttcctt ggcgtttgcc aaatgatctg aaattcttca aacaaatgac agaagcaaat
     5761 acactagtga tgggacgaaa aacattcgaa gggatgggta gccgtccgtt gccgaatcgt
     5821 cagacgattg ttttgacgag agattcttcc tataaagcag aaggcgtgca tgtcatgcat
     5881 agtgtggaag acgtgcttgc tctggaaaaa gaaacagacg gtatcttttt catcgctgga
     5941 gggtcagctg tttatcaaga atttctgcca ttttgtacga tattataccg tacagtcatc
     6001 catcatgtat tcgatggaga tgcttatttt ccacctgttg actggtctga ttggtcactg
     6061 atcaatacta gtcaaggaga aatggatgaa aaaaatcgtt atccgcatca atttgaaacg
     6121 tatcagcgta atgagaatcc tgtaaaaagc gggacaggcg aattgacgat ataaaaaagc
     6181 tatggataga ctagctgtta tttagagctg tcccatccat agctttattt tttttattaa
     6241 gtaaagaata aaacagagaa gtacataaaa cctgcaccta acataacaaa caaatgccaa
     6301 acaacatgca tatagcggat agaattcaag ctataaaaga atgcgcctat cgtgtaagaa
     6361 agcccgcctg ctaccatcaa aataacacca gtcattccaa gagagtgata aagaggaaca
     6421 gcagccacga cacagagcca ccccataaaa atatagatga tcgtagatac ttttgatact
     6481 ctctcccgtt tatgcaacgt caacgcttta tatataatgc caagaatcgc aaacaaccag
     6541 attaatacaa ataaagtcca acctagccat cctcggatac tcagcaaaca aaaaggagta
     6601 taacttcctg caatcaaaag aaaaatcgaa ctatgatcga atacttggaa cacctttttt
     6661 gcttttgtaa aaatcaatga atgaaacaaa gtagacgtta aaaataaaag aatcatcatc
     6721 gatccataga tagcataaga gacaatatgg agggaggaat gcaagtgggc accttttact
     6781 aaaagaacca ctagtcccgc gatactcaat ccagtcccaa ttccatgggt gactgcatta
     6841 aacacttcat ttaatatttc atacgttcga ttaaatttcg ttttttccat gaaaacggct
     6901 cctttactag gtgtaattaa tgaaaaatca ttatttgtct gttatactaa aaatagaaat
     6961 tgtcttacat gtagtttaac atgaataagg catcttgtta aagaaagaga gagagaaaat
     7021 aatgacaaat gtaaaaatcg taacagattc ttcatgtacg atggaaaaaa atgtacgcga
     7081 tgctttaggc attcgtgtca tgccgctatc catcatgatc gacggaacag tatatcccga
     7141 tgatgaccaa ctagacggcg aaagatttat ggaaatgatg gcgaaagcaa aaaatctgcc
     7201 caaaacaagc caaccaccaa ttggagaatt catctcgatg tatgatgagc taggagaaga
     7261 cggcagtgaa gtgatttcga tccatatgac aaaaggcttg agtggaacag tagaagcagc
     7321 aagacaagcc agtaatctaa caaaaacgaa agtaacggtt atcgacagtg ataccactga
     7381 ccaaggatta tcttttcagg taattcgagc agctgaatta gcaaaagaag gtaaaacagt
     7441 agagaaaatc cttgaagaag tcaaaaaagt acaagacaat acaaaattat acatcggaat
     7501 atccacacta gataacttgg taaaaggtgg aagaatcagc cgaacaactg gtttgctgtc
     7561 tagtgttttg aacatacgcg tggtgatgaa tttcgcccat tctgaattaa tccctgtaac
     7621 taaggggcga ggaaagaaaa cgttcgataa atggtttaat aatttgaaaa atgaactgaa
     7681 agaattgcca aatgtgcgac aaatcggtat ttcacatgcg gatgcaaaag aattggcgca
     7741 agaattcaaa gagggtttgc aagaattatt cccggacatg catatccctg tactgcatac
     7801 gaatccggtt atcgctacgc atactggtaa agacgcgttt gcaatcatgt attatgtaga
     7861 ttagtcgaaa agaggataag ccctcagcct gaaaggcttg cagcttattc tctttttctt
     7921 tataaaatta ggaaaataat tgttttcttt tttcataaag actacctttt tgataaaatt
     7981 tttgataaca ttagaaccaa tcgaatacaa gaggtgaaaa aatgaaatta acgaaacgac
     8041 atttgatcct cgttttgttc ccattattaa ttgcgatcat catctatgca ggtttagctg
     8101 cttctatacc gaaagctggc ccactaatga aaccagtaac tactgtgaga gaagatccaa
     8161 ataaaaaaga aaaacttcac tacatagcta tcggagattc gctgactgaa ggagtaggag
     8221 atcaaaccaa gcaaggagga ttcgttcccc ttgtcgcaaa tgatctaaaa gaccgttata
     8281 atttgaccgc ggttgaaaca gaaaactatg gtgtaaatgg tgaacgaagt gaccagatct
     8341 taaagcgagt aaaaacaaaa gaagaaattc gaaacaatat caaaacagct gattttatca
     8401 cactgactgt tggcggtaat gatttgatga aagttatcca aaataattta ttcgggttaa
     8461 cggtcaattc ctttaaaaag ccactgaaaa actatcagga aaatgtcaca gaactattgg
     8521 aagaatttcg atccctcaat aaaaccgcac ctatttacat tttaggcatc tacaatccat
     8581 tttatttgaa ctttcctgag atcactgaca tgcagacaat tgttaacaat tggaacaaag
     8641 gaacagaaac ggtgacaaaa aaaatgccga actgctactt tatcccaatc aatgatttgc
     8701 tttatcaagg attgaatcag gaagtaggtg tcacagaaga aggaacagat caaacaacta
     8761 gcacgacaga aaatctaaat ggcatcaaaa ataatgtgct ctatgaagaa gatcatttcc
     8821 atccaaataa tttaggttat caattgatgg caaatgcagt gagagatcag ctgatcgaga
     8881 cacaaaacca atggttagag aaggaggatg atcaataaac atgaaaacaa gatctgacgt
     8941 atcttcaaac aaaacaaaga aaacaaatta ctggaaattc gccttcctta tccttcttgg
     9001 ggtagtactt ggttcgaccg tatttttagg cagccgtatt tttgctaatc gggaaccaga
     9061 actcccagaa ataccagctc ttacggaaag acaaggagat cctgtcttaa cgatcaattc
     9121 aaataaagaa aaagtcaatc aaatcatcag ctttttcctt agtgagtatc aaaaagatag
     9181 tgatattgaa tataaatttt atttggaaaa tgaagcacta ctcaatggta ctttcgaagt
     9241 actaggtttt cctatcgatt tctatttata ttttgatccg tatgtgatgg aaaacggaaa
     9301 tgtccaacta aaagctagaa gtctttctat cggaacattg agtttgccaa tcaaagatgt
     9361 gatgaatatg atcaagagaa actataaatt accagattgg atcgaagtca atacagatga
     9421 tctgactatc atgcttaggt tggatcaatt ccgaatgcaa aacgggatgt atattaaagc
     9481 agataaaatc gacttagtaa atgatgacat tcggtttagt ctatatttgc caaaagatac
     9541 ctctgatgct tcaaacaact caaataccaa caaaactagc accagcagta ctgaaagcaa
     9601 gacaaaagaa aataaaaaat catcggatga gtagtattag agggggaatc ataatggaac
     9661 gagcaatatt tgcaggaggc tgcttctggt gtatgatcca gcctttcgac acgcttcctg
     9721 gtatccatac agtgatgtca ggatatactg gagggcatgt accagatccg acttatgaac
     9781 aagtaaaaag ccaaacgact ggacatacag aagcagtgga gattatctat gatccaacat
     9841 tgatttcata tgaacaatta gtagaacttt actggcagca aactgatcca actgacgctt
     9901 tcggacaatt cgaggatcgc ggtgacaatt atcgcccggt gatcttttat ttgacagaag
     9961 aacagcggat cattgctgaa aaaagtaaga aacagttagc tgaaagtgga cgtttcgaac
    10021 agccaatcgt tacaaaaatc gaaccagccc aaccatttta tctagcagaa gaagaccatc
    10081 aagagtatta taaaaagcat cctgaaaatt ttaaaagaaa ccatgcacgc cgggctgcct
    10141 ttatcgaaga aaattggagg aacgaagggt gaatcgaagc ttttttcatt atttaatgac
    10201 actgcgaggc ggtggcacac atgatgcttt atctgttttc gctacagaag ccggtaaaga
    10261 catccaattt cctaagcaca gctctagcta cgaagaaatt tctaattatc tggaactgaa
    10321 tgtcgactat ttgccgtcca tggatatctt tgacgaagca tgggaaaaat atttagaaaa
    10381 taatcatgac atataagaga tagttttgta ctttatgatc aaaaaagttt tttgtccaat
    10441 agcctaattg aaagaattat ttttatttca gctatctagt cgcatttttt tgatattttt
    10501 cttataataa agaaagaatg aaaaaaagag ggatggattg atagagattg acaaaaaaac
    10561 aacgctatat taatcgcttc tggcttgtat tcaaatactt acttgtttct gtattccttg
    10621 cgttcatgtt gcggggattt ttattcatcc cggtaccagt ggaaggcaat tcaatggaaa
    10681 acgtgttgaa gcaaggtgat atggttgtga tggaaaaatt ttcggagatc agacgatttg
    10741 atattgttgt ttttcaatta gcagatggca cgatttatat caaacgagta atcggtcttc
    10801 caggagaaaa tgtcagctac caaaatgatc aattgaagat caatgggaaa gtagttaagg
    10861 aaccttatct aactaaaaac ctgaaatcag atcatgcaaa tgcatcctat acgacggact
    10921 ttacactaca agagctaacg ggacaatcca agcttccgga agataattat tttgtacttg
    10981 gagataatcg aagagtttca aaagatagtc gttcgtttgg cacgatcaat aaaactgata
    11041 ttctaggtaa agcaagattt gtctattatc cacttgatga aataaaatgg atccagtgag
    11101 aaacaataaa gcgtgcagtc tgttgagact gcacgcttta ttgtttaatc caaaatcagt
    11161 ttactacctt agtacgtaaa atcaaacagc tcgtttaaac acttttctag cctctaaagt
    11221 tttgataaat gaataaacaa ccattatttg aatagggatt tggatcatat tcctgatgaa
    11281 tctacctaga aaaattactt tgaaatctgc accaaacaaa acagacatca gccaagaatt
    11341 gataaaaagg ctgactggga tcataatcaa taattgggca gcgatgacgg aaggcaggtt
    11401 tatcttttta tgatataaaa ataagccatt aataaatcca ccaaggaaag ccgtgataag
    11461 aaaagcagct tgaaacgttc ctgaaccaaa tatcgtgaaa tttaaagtgt tcgacaacat
    11521 ttcaagcaaa ccagcccaga tcggtccata tagataaccc ataagcgcca tacttaaaaa
    11581 tccgaatgtg atttgaaaat aagcaggacc aatcgctatc ttgtataaga tgacatcaag
    11641 ggctaataaa agagcagagg tcgacaacaa tcttgcattc atttcgggca atctaaaaac
    11701 gtcttttgca atcaaagtgt tcaaaatatt ctctcctttg tcagttaata ataaaaggat
    11761 accataaaat
//
LOCUS       DARPZJ010000071        11520 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.074, whole genome shotgun sequence.
ACCESSION   DARPZJ010000071 DARPZJ010000000
VERSION     DARPZJ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.074"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(68..1747)
                     /locus_tag="SLE23_002396"
     CDS             complement(68..1747)
                     /locus_tag="SLE23_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEI8469267.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            2295..3797
                     /locus_tag="SLE23_002397"
     CDS             2295..3797
                     /locus_tag="SLE23_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469268.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNLKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3810..4472
                     /locus_tag="SLE23_002398"
     CDS             3810..4472
                     /locus_tag="SLE23_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469269.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4573..4776)
                     /locus_tag="SLE23_002399"
     CDS             complement(4573..4776)
                     /locus_tag="SLE23_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEI8469270.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(4887..6071)
                     /gene="iadA"
                     /locus_tag="SLE23_002400"
     CDS             complement(4887..6071)
                     /gene="iadA"
                     /locus_tag="SLE23_002400"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HEI8469271.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(6228..7967)
                     /gene="yfcC"
                     /locus_tag="SLE23_002401"
     CDS             complement(6228..7967)
                     /gene="yfcC"
                     /locus_tag="SLE23_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HEI8469272.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(8740..9354)
                     /locus_tag="SLE23_002402"
     CDS             complement(8740..9354)
                     /locus_tag="SLE23_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8469273.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(9960..10337)
                     /locus_tag="SLE23_002403"
     CDS             complement(9960..10337)
                     /locus_tag="SLE23_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469274.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(10637..11518)
                     /gene="galU"
                     /locus_tag="SLE23_002404"
     CDS             complement(10637..11518)
                     /gene="galU"
                     /locus_tag="SLE23_002404"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEI8469275.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         3440 a         2433 c         1947 g         3700 t
ORIGIN      
        1 tatttgtttt tcgcaaaaaa agagcaagac gagcactcta tagagaggtt catcttactc
       61 tttttgttta ttttttattt cgacgttgag tagcttccat aatgactggc aagatcactg
      121 ggcggcgttt tgtttgttca aataagtaac ggcctaattg atctcggatg tcttgcttta
      181 atttgctcca ctcaaaatca ttgctttcta aatgtttctc aacgattgtt tcaatcatat
      241 tgctgctttc tttcatcaga tcacggctag cttttacgta aacgaatccc cgtgaagtaa
      301 tttgaggttt tgaaatgatt ttcttttctc gccgactgat agtgacaacc gctacgaaaa
      361 tcccgtcttc tgacaagatt tttcgatcac gtaaaacaat gtttccgata tcacctatgc
      421 ctaatccatc aatcattaca ttttctgcac ttgtagttcc tgcaacactc atacgcttgt
      481 tcttatattc cagcacgtct ccgcgtccag taatatagat atttttgtat ggcatcccta
      541 ctgcatgagc caaatctgca tgagcagcta attcacgata ctctccttga actggcacaa
      601 aatatgttgg tttcatcaaa ttgatcatta attgcaagtc attaggattg gcatggccag
      661 aaacgcgcat attctcagag atcaacttca ctgttccacc agctcgataa atgatatctt
      721 ccgttttcgc cacgatggtt tccatcgcga tgcttggcgt agtagtgata taaaccaaat
      781 ctccttcttc aatcttgaca ttacggtgtg taccgtttgc cattttttgc agagacttga
      841 tgggttcacc cattcggcca gtttctaaaa tgatcagttc ttctggatca tagtttttca
      901 tgtctttcaa cgtaacaagc agatcttcac ttggtaattg aagtttttct aaacgcatcg
      961 ctgtgcgaat aattcgttcg aaatcttgac cagtcaagac aacttttcgt tgtgcttttt
     1021 ctgctgcatc caatacttgt tgcactcgtt gcaaattact tgctacacaa gcgacgatga
     1081 tacgcccttc ccaatatttg atcgtatcaa atacttcatc tgctatttgg gcttcagaag
     1141 ctacaggctg aggattttct gcatttgccg attcacttag taaggctaag actccttctt
     1201 tgccgatttc cgccaatcgt gcataatctg tttgatacat tgggatagcc gtttggtcaa
     1261 atttaaaatc tcccgtataa acgatactac cttcttttgt tttcagattg atccccactg
     1321 aatctggtat cgtatgagtg gtacggaaaa agctcactac tgtttcacca aagtctattt
     1381 ctgtatgctc atctaccaca tggaaatcct taaatccttt ggctgcttca ttacgactga
     1441 cattcaattt tgctaactcg atcgtcaact ctgtcccgaa tactggtaca gaaatttttg
     1501 acaacaagta aggaagtgcc ccgatcgcat ctgcatgtcc atgtgttaaa aagacaccag
     1561 ctacacgatc aatgttttct tctaaatacg taaaatcagg gattacgacg tcgatcccca
     1621 acaactcatt ttcaggatat tttagcccac aatctaaaat aaaaatatcc tcgcccactt
     1681 ctgcgacata catgtttttt ccattttcac gaacgccgcc taatgggata attttaatgg
     1741 tactcacaaa cttcacctct tcttatgaca tccaagttta aagatgtcga ttttcttctt
     1801 tatctaaata tatgagccat tccaatgaag catatgcaaa atcactattt ctcaacttat
     1861 ggagaatcag caggaaaatt accagcacat ccgcgttctg acagttggat gggcatttta
     1921 ttttggatat acttcattaa caaaatggat cttttgcgaa acgctatagc cagaatactt
     1981 atataagtat tcagctgttc cccattatta tacaacaaat aaactaaatc gctagtatca
     2041 gcaattgtta gaacaactat gcacgtaaaa atccctctgt agcatctagg atttcttttg
     2101 ctattcctct ttcatttctt cttcgtcggt ttgaaacata cttttttcat tttaccacat
     2161 tttttgcaat aactatagtg actttttata tatacagaac ctcatgttga tggtgtgcaa
     2221 acagcataag atttaagcta gctttaagat aggttgtcta ttatcaaatg catctactag
     2281 gagggatgca aaatatgaat tttatgaaac gtgcatggaa aagtacaaaa gtaaaatggg
     2341 gacgttcatt gttattgttt gccgtgttca cagccattct tatttttgtg ctagctggcc
     2401 tcacgattcg aagcgctgca gaagaagcag cgaatcaagc acaaaaagaa gttggagcaa
     2461 cagtgacttt aagtgccaat cgagaagctt catttaaaaa acaggaacaa acttcttcaa
     2521 gcggttctac cactgaagaa cgtccagatc caggcagttt ttctcttaca ccagtttcct
     2581 taacggacgc ggaaaaaata gctgaattag ataatttaaa gagttattcc tttgaaagtt
     2641 ccgcctcagc tatggcaaaa gatggaataa ctgccatcac tagttctgat tcaagtgaag
     2701 acagttcaga aactactgat gcaggcggtg aacctgctgg aggaatgggc gggaatccgc
     2761 aaatgactca agcagacttt caaatcagtg gtgtgtcagc aactgcacaa aatagtaatt
     2821 tttctgatgg aacagcaaaa atcacggatg gtgaaggaat agatgacagc gacaaaggca
     2881 caaacaatgt agtcattgat tctactctag cagaaacaaa tgacctggca gtcggagata
     2941 ctttcacaat cacgagtact gaagatgaag ataccactta tgaaatgacg atcaaaggaa
     3001 tttatgaatc cagcgaaaca agcggcagta tgggtatgaa attcaacttc atgaatccgt
     3061 cgaatacact ttacacttct tacacttttg caaatgaact aaatgggaca tctgacgata
     3121 acacgataga ttctgctatt tacactctat ctgatccaga taaaatggat gagtttctca
     3181 aagaagctga gaagctgatc gacacagata catttagctt acaatcaaat gattccatgt
     3241 atcagtcaat gttggaacct ttaaacaacg tggcaagttt ttctaaaaat gttgttttac
     3301 tagtggctgt agccggtatt atcatactta ctctgatcat tatgattacc attcgggagc
     3361 gtcggcatga gttaggcgtc ttgctatctt taggagaatc cagaagtaaa atcattctcc
     3421 aattgtttac cgaagtggct atttgtatga ttcttgcatt aggagttgct tcgcttagcg
     3481 gaaacgtcgt cgcgaatgcc gtgggacagc agctacttga ccaacagaca gaaaccacga
     3541 cacaaaacca gcaagctcct ggcggtggac aaatgccagg taacagacaa gaacaaggcg
     3601 gtcaacgcga tggtcaacaa ggaaccacga ataatccatt tgctgtttct gatcaagtca
     3661 gcgaattgga aatcaatgtc aaacctgcac aattgggact attagccgga gtagcatttg
     3721 gaatcagtct gttttctgtc tttttagctt ctatagggat attaagatta aacccaagaa
     3781 aaatcctatt aaactaaagg aggaatttga tgttacggac agaacaattg ggattttggt
     3841 atcaagatcc gcaagatgcg ctttataaag atgtagaact gaatttcgaa gctggaaaaa
     3901 tgtacgctat tttaggagca agtggttctg gaaaaacgac ttttctttcg cttatttctg
     3961 gactagatgc accaaaagaa ggaaaggtat actatcaaga tcgttcactg aacaaaatcg
     4021 ggttaagaag ttatcgtaaa aatgatgtct cgattatttt ccaagcttac aacttgcttc
     4081 cttatttatc ggctctagac aacgtcatag cagcaatgga aatcactaag accaagcaag
     4141 agaattatcg acaagttgct ttagatcgac tggctcgtgt aggaattgat gaaatattag
     4201 caaaaaaaca ggtgaccaaa ctttcgggag gtcagcagca gcgagtcgct atcgttcgtg
     4261 ctatctgctg tgaacatcaa ctaatcgtag cggatgagcc tactggaaat ctagatgaaa
     4321 caacttcaca agatatcgtc aaacttttcc aagaaatcgc ccatgaacaa aatcgctgta
     4381 ttatcatcgt gactcatgag attgaagtag caaaaagctg tgatgaagtc tttgaactaa
     4441 aaaataaaaa atttcaaaaa atcgaagttt aaaaaacagg ataatgatca aataaaaaat
     4501 ccgaaccata tctgtctcgc agatatggtt cggatttttt atttgcttga ttcaattagt
     4561 aataagtggt ttttattttt tttcgtcttt tcgagaaaac ttgtctttga cttcgtcgcc
     4621 taaatttcga gctttttctt tgatgtcagc acctagtgat tgtgctttcc cttctgtttc
     4681 tttgctcttg tcgtctgttg ctttgccgta tgcttctttt ccttcaccga ctactttatc
     4741 tttcatatct ttagaacgtc cttttaaatc tgccattgtg cttcctcctc ttagtttgtt
     4801 tattgatcta ccttcagggt aacatcaaca acagatacag acaaacagaa cgctcgtttt
     4861 ctaaaaaaga tagttagagc tgttgattaa aaactttttt cgaaagtccc ccatactttg
     4921 acttcttttt cttggaccat tatttctcct ttagcgataa ctgtatcaat atcaagcgtt
     4981 tctttatcca agatacacag atctgcatca gcaccaattt cgatttttcc ttttttatcc
     5041 aatttcaata tacgtgctgg attactggtt atagctcgta aggcgatttc caaagggata
     5101 ctttcttttt gcacagcttc tttgatccct actagcaatg ccttggcact tcctactcct
     5161 aaccctagga aatgattgtt ttcatcaaaa taaggcaagc ttccttgtcc atctgaggtc
     5221 atcgtgaaat tatctaaaga aacatcttcc tcgatcaatc gtttcagtgc tttgctgaag
     5281 cgaacttcac catctgtctt ctcccaaaaa tcaggatctt cgctagcagt gaagtcaatc
     5341 gtgccaccac gtttggcaaa tgccacgcaa gcttcaaata attctggtgt gcgatttgca
     5401 tgagtaggca aaaattgtgt gatcggaatt tctgtttctt ctacgattcg tgtcaatagc
     5461 tctagctttc tttttcctcc gcctaagtgg acattgatga tcccagcttt tccggataac
     5521 atgcctccta cacgagcatc tgctactgca cgagcgaact cttcaaaact tggctgagaa
     5581 gaacggtgat cggatactgc gatttctccg attccgataa ttttatcaat tgtcaaaaag
     5641 tctttgatga tagaatctgt tactgttttt accggcaatc ggtacgaacc ttcgtataca
     5701 taagtggaga ttccttctgc ttccagacct ttcgctttgc tgatcaacgc agtcatatct
     5761 ctaccttctc cgtctgttcc caaacaaccg acaactgtcg ttacaccagc tgtagtcaat
     5821 tggctcaatg tgacttctgg cgttcgattt tgataaccgc cttctcctcc tccacctaaa
     5881 atatggaaat gacagtcaat gaaacccggg gttagtactt ttccctcacc tgaaagttct
     5941 tctacttcca ctccttcgta gccgccttct agctgttctt ctacagccaa aatcttccca
     6001 ccggcaatca gtacatccat ttttcctaag taatctggtg caaacacttc aatttgtcga
     6061 atgattttca tacatttttc ctctttcttt aagtataact gatgatagga tcttaaaaaa
     6121 taatccaaac gataggatct ttactccttt gattttaccg taaaatgacg gttcttggag
     6181 tccttatcta ctgtttggat tactttttta tttacaggtc tccagtacta ctgcagacct
     6241 attgcaatgg caatcatgat gaaaatagtt cctaaaacaa acaggaatcc ttgcatcttg
     6301 atttggaatc ttgcccattt tgcccattcg atccgtgcaa cacctagcac accaatcaag
     6361 ctggctgata cgggtgtaaa agcgtccata aaacctgaac caagctgata agcaagaact
     6421 gctacttgtc tggatacacc tactaaatct gccagtggag ccatgattgg catagtcaaa
     6481 gctgcttgtc ctgaatttga tgtaacaacc aagttgaaca aactttggaa gatgtacatc
     6541 gcccaagcac caatgacagc tggaacaccg gtcaacgccg tcccgatccc atgcaaaatc
     6601 gtattcaaag ctgaaggaac agatgcatca gatcctccca agacaagaag aatccctttg
     6661 gccataccta ctacgattgc tgtaccagct aaatcagctg caccagattg gaaagaagaa
     6721 gcgatgtcat tgactttcat tccatctaat ttgaaaagaa cagcaatgat tccagcaact
     6781 aatcccatca caaagaattg agaagcgatt tctggaatgt aatagccttt ttgagtcacg
     6841 ccccaaacga tccagacaag gacaactaac atctctaata agatcaattt atgcccaagc
     6901 atgaattttt tattttcatc agatgtcttt ttgatatgag aacggaaata atcatctgat
     6961 ttgtaagtca acgaactttc tggtttttta cggatttttt ctgcatatat catcatataa
     7021 ccagcggcta atgcagtaac aactacccac ataatcaatc ggaatgtcgc accagacaac
     7081 acggggattc cagcaatccc ttgagccacc gctacgctaa acgggctcat ccaagaggtc
     7141 gcatttccga cttgagatgc gacataagtc acggttactg ctacgatcga gtcatatcct
     7201 aacgcaatga caaatggaac catcaccatt gagaatggaa ttacctcttc tgccatcccg
     7261 aatgtagcgc caccgaatga aaaagcaaag aataatagcg gtaaagctaa acgctccagt
     7321 cccttagttt tactgataaa cgcatagata cctgcgtcga tcgctccggt acgcataata
     7381 ataccaaaag cacctccaac aacaaggatc aatgcagcga tccctacagc agatccatac
     7441 ttatctccag atactagtcc ttcaaaaaca aaatttaaga aaccaaagcc gccaaaatca
     7501 tctgttcccc atattttggc tgttttatgc aattttttag aagtatcata gatattttcg
     7561 ccgtactgat cgtaaagcac atcatctgtc aaggagattt catctagttt ttcctgcgta
     7621 agattttttt ctccgtcagc aatgactttt tccaatcctt tttccggaac atccagtttt
     7681 tcacgttctg ctggatgatc ttgcagttct tctaattgat caaacacata cgacttatcc
     7741 agctcgtaag cataacggaa ggaatcttga cgtaaaacag tacgagtact tgtttcgcca
     7801 tttgcatctt tgtattcaat atcttgcgtg ctgaactttc ctgctggaac gacaaaagtc
     7861 agtatccatg caaagatgac tacaccaaaa ataatgacat acgtatgggg tgtcgataat
     7921 ttagtgaagt cgcgtttcgg ttttcctgaa gaatttgttt tcttcaaatt tatttcttcc
     7981 tttctttttt cagtaatttt gatgaataaa aaatggataa tcaaatgaat tatacagtaa
     8041 aaatgacatt tccacatgaa taatttatta gaaaatcact tttttctatt ttgttttttt
     8101 tctcctatgt atgattattt ttttctcttt ccatttatat taagtatttt atttctctgt
     8161 ttttccttaa aattcttttt ttatttttag attagagaaa atctcgtcct gtttttttca
     8221 ttttacaatc attgaaaaat tgaatttcat tgcaaaaaaa ataataaaca cttataaata
     8281 tccattatct atccttcaat ttttgtgtat tttatttcta ttagaaaaag gtatcctgtt
     8341 ggacaatttt gttatatcag gtaaacttca ttgcaataat gataacaaat gtactataat
     8401 tactttgtaa agagttttgg ggaagactct ttcatcaacg tgtattaaga gacaagaaag
     8461 aatccatatg gattctttct tgtctctttt tccactactt tttatttttc tgacactaca
     8521 tattcttata actcatttct cataactgtg aaacaactta taaaaataac aaactttaaa
     8581 caaaacaagc ttaaaatcaa agatgatcca tcttaaaata actaaaacaa aaaaagtagt
     8641 cgttgttaat cctcattaat aatcgttttc tttttttcaa acgctccatt tttatgtgga
     8701 acattatttt tttaaggaac tttgtcaaca tgtggataac tattttccac ttgtgtcctg
     8761 gactagctgt tttgctgtaa aatacaaaac ttgctgcagc aaaaagatcg ttgcaagaga
     8821 ggctgttccg cagatcgctg gatctagatt tggcaaagtc aagactgcat catgtaaatt
     8881 ggcgtggttg tccaaaacca aatcagcaaa ttcaaataat cgcaaaccac tgctatgttg
     8941 cgatttgata cttcgtgaca aatcaaatcc agtaacaatg attaatggat gaccattttc
     9001 tttgatccac tgagctagtt cgatgattgc cgggtttctt ccttcattcg aaagaagaag
     9061 aaaaatgtct tctgatttga cagaaagctg atcaataatt gcctgtcctg caccttctag
     9121 cgtttcatag acacctccgg ctggattttc aatcaatata cttggtacaa gatccggggt
     9181 ttgatcccaa aattcaaatg ctacaccact tagtgtgcgg ctagcatata tctgcaatct
     9241 accaccttga ttaatttgtt tcgcgatcca agtgccagct tgaagcatca gcggctcttc
     9301 tatccttaat ttctcttcca attggtgata atagtcaaaa taacataaac tcatttatct
     9361 ctcccgccta gctatacttg acatgaatag aaacagctgc ctaatctaag gaagtacata
     9421 aaaaaacagt agttagacag taacacatgt ggtctttgct gtttcaaaca caaaaaaggc
     9481 attgaacgaa tacgcccaat accttgacat agcaaataaa acaacgtgca gaccatggaa
     9541 aatatctaca taggggtaga attttcaccc tagattaggt acaataaatt aggtcgatgc
     9601 actgcattga ctatggcaaa atgatcggtc agggtgtatg tgtgtgactg gtcattccct
     9661 gattcttagc gccaactaag ggtcagggag ccttttttta ttcagctgtt tctatctgaa
     9721 tttattgtaa gtaatctctt atccaagtgc aagcaagaaa atacaaaaaa acattggtat
     9781 gatttatata tatataaata acataaaaaa aggaatggct tatcccgata caacaagcat
     9841 tcctttaaaa aagattcttt tatataagtg aaaaaagctt ttttccacca attaaataaa
     9901 tctctcatct caatagttta tccattattt tatctttttt tgcgtatacc tactaaatat
     9961 taccgtcttc ttctcgttct tctactttgt tcgagagaat ctgtactaga aaaagtagtt
    10021 gtatgtctac cttttctgcc tatccgagac tttcttttca tatatgggat ataaatgatt
    10081 agatacagta cagcaaaaaa taaagcaaat acgcaagctt cccaactacc taacgccaat
    10141 tcaaccatca aggtagcaac cccaacggat gctgcatacc agataaaaat cagaaacgtt
    10201 tctttttttc tgaccatgcg aaacatgata aatagactaa taagcaatag tggcaacaca
    10261 aatatccaat tgcttccttc catcagccac ttgagtatat caagcagcga ctgtgcaaca
    10321 gcgactaatt ttcccatagt gaacacacac ctttttttat aattaaaaaa ttcgcctttt
    10381 tattctacta tgaatcttct ggcttggctt tcatttctct tatgtaatca ttttctttta
    10441 tacaacttaa aaaaaaatta aaccattagc ataatatttt ctgaatctat tcacgaaagt
    10501 ctttttctat ctttcgtttt ccacgactca actgatctag agtcaaaaaa ctaaaacgac
    10561 agttgcgcaa atgacgcaca agctgccgct ttaataacaa atagcctttc attctcagca
    10621 ggccacttat ttccagttaa ctttctgttc ttagcttttt actcaactgg ataatatatg
    10681 cacttaatga agtcccaatt tccgaatgtt gaagtccata ttcaatattt gtcttcatat
    10741 atcctaactt atcgcctacg tcgtatcttt ttcctttaaa ctctctcgca tagaccgcct
    10801 ctgtctggtt aagagtctga agtgcatccg ttagctgtat ctcgtttcct gctcctggtt
    10861 cttgagtttc taatatctca aatattttag gagtcagtag ataacgtccg ataatggcta
    10921 aattacttgg tgcttttccc atttcaggtt tttctacaaa cccttttact ctgcaacgac
    10981 ccttttcgct atctgtttta ggatcaataa ttccgtattt agatgtttca ttttctggta
    11041 cacgcatgac ggcaacagcg gaagcttgtg tttcttcata atccatcatc aattgttgag
    11101 tcaatgggat atcatctttc atcaaatcat cccccagcat gacgacaaac ggttcatttc
    11161 ctataaatgc ttttgcttga agcacggcat cccccagtcc tcttggatga gattgacgga
    11221 tgaagtgaag attgacttga gtcgtttctt caactaaagc gagtaattct gttttttcct
    11281 tttcccgcaa attgttttcc aattcgatat ttgcatcaaa gtgatcttca atgggtcttt
    11341 tttcttttcc cgttacgatc aagatgtctt cgattcccga atccaatgct tcttccacaa
    11401 taaactggat cgttggttta tccacgattg gaagcatttc ttttgccatg gcttttgttg
    11461 ccggcaaaaa acgtgttcct agcccagcgg caggaatgac tgcttttttg accttcactt
//
LOCUS       DARPZJ010000072        11428 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.075, whole genome shotgun sequence.
ACCESSION   DARPZJ010000072 DARPZJ010000000
VERSION     DARPZJ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.075"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..440
                     /locus_tag="SLE23_002405"
     CDS             <1..440
                     /locus_tag="SLE23_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HEI8469276.1"
                     /translation="TFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKAASEKQEATR
                     HLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEIIQNGRTSQSV
                     RGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            456..605
                     /locus_tag="SLE23_002406"
     CDS             456..605
                     /locus_tag="SLE23_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469277.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            681..1274
                     /locus_tag="SLE23_002407"
     CDS             681..1274
                     /locus_tag="SLE23_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEI8469278.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            1287..2186
                     /locus_tag="SLE23_002408"
     CDS             1287..2186
                     /locus_tag="SLE23_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEI8469279.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            2189..2662
                     /gene="ssb"
                     /locus_tag="SLE23_002409"
     CDS             2189..2662
                     /gene="ssb"
                     /locus_tag="SLE23_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8469280.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSTTSPSPTTFEQRDTNNGLDASQNPFGGQSIDISDDDLPF"
     gene            3028..3288
                     /locus_tag="SLE23_002410"
     CDS             3028..3288
                     /locus_tag="SLE23_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469281.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDQFTRLMGI"
     gene            3733..3939
                     /locus_tag="SLE23_002411"
     CDS             3733..3939
                     /locus_tag="SLE23_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEI8469282.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            3939..4190
                     /locus_tag="SLE23_002412"
     CDS             3939..4190
                     /locus_tag="SLE23_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469283.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTTETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTELEN"
     gene            4206..4622
                     /locus_tag="SLE23_002413"
     CDS             4206..4622
                     /locus_tag="SLE23_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469284.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGACYIMK"
     gene            4604..4876
                     /locus_tag="SLE23_002414"
     CDS             4604..4876
                     /locus_tag="SLE23_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469285.1"
                     /translation="MLHHEVIRRIQKDFSCMEEMKYFVQNVEEQLYLESETSQTKVTV
                     SHNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKSELVENFMD"
     gene            5043..5444
                     /gene="tnpA"
                     /locus_tag="SLE23_002415"
     CDS             5043..5444
                     /gene="tnpA"
                     /locus_tag="SLE23_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEI8469286.1"
                     /translation="MSEIHYGRGYVYSIQYHLVWCVKYRHDVLYGQVDIDVKQFLKQI
                     ADDNNIKIIEIESDKDHIHLLIECTPQHYIPSIVKVFKGASARLLFKKHPELKQLLWG
                     GHLWNPSYFVATVSENTEEQIRKYIQNQKKK"
     gene            5456..6601
                     /locus_tag="SLE23_002416"
     CDS             5456..6601
                     /locus_tag="SLE23_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8469287.1"
                     /translation="MLQHRAYKFRIYPNQEQEILMTKTIGCSRFVYNYFLNLWNHEYT
                     TTGKGLSYNSCSAMLPQMKRNAETIWLKEVDSIAIQSSLKNLSDAFSRFFKKQNKRPQ
                     FKSKKHPIQSYTTKNVNNSIEIRNNFVKLPKLGFVKFAKSQEPKGRILNATIRKNSSG
                     KFFVSILCEEEIVEFPKSNSAIGIDLGITDFAILSDGQKIDNNKFTSKMAKKLKREQR
                     KLSKRALLAKKKGVNLFEAKNYQKQKRKVARLHEKVMNQRNDFLNKLSTEIIKNHDII
                     CIEDLNTKGMLRNHKLAKSISDVSWSSFVTKLQYKANWYGRKIIKVDKWFPSSQICSN
                     CGHKDGKKSLEIREWTCPVCHAHHDRDINASINILTEGLRLHVMGLA"
     gene            6839..7102
                     /locus_tag="SLE23_002417"
     CDS             6839..7102
                     /locus_tag="SLE23_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HEI8469288.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            7096..7446
                     /locus_tag="SLE23_002418"
     CDS             7096..7446
                     /locus_tag="SLE23_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEI8469289.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(7470..8084)
                     /locus_tag="SLE23_002419"
     CDS             complement(7470..8084)
                     /locus_tag="SLE23_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8469290.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            8398..8820
                     /locus_tag="SLE23_002420"
     CDS             8398..8820
                     /locus_tag="SLE23_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469291.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            8830..9033
                     /locus_tag="SLE23_002421"
     CDS             8830..9033
                     /locus_tag="SLE23_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469292.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            9244..9828
                     /locus_tag="SLE23_002422"
     CDS             9244..9828
                     /locus_tag="SLE23_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8469293.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            9997..11322
                     /locus_tag="SLE23_002423"
     CDS             9997..11322
                     /locus_tag="SLE23_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEI8469294.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
BASE COUNT         4152 a         1802 c         2193 g         3281 t
ORIGIN      
        1 ctactttctt agctaatatc caaaaatttg tctctcactt gttggaagtc gtaccgggac
       61 aaatccagtc aacagatttt ggatcaacgt tacaagaggt gaaagcagcc agtgaaaaac
      121 aggaagcaac gcgtcattta ggtgtttgtc caaaatgtcg ggaacaagaa gtcttgcttt
      181 atcaaaatgt ggcggcatgt acgtctgaag cctgtgattt taaattatgg acaacgattg
      241 ccaaaaagaa actcacagcc acacaactga aagagatcat tcaaaacggc cgaacaagcc
      301 aatcagtcag aggactaaaa ggtcagaaag gttcgtttga agcaacgatc gttttaaaag
      361 aagactttac aacaggcttt gaattttctg aaaagaaaaa aacgaactat aagaaaagaa
      421 cacgccgcac tacaaaataa tgaaggggtt atcctatgcg aaatacaaca cacaaacaac
      481 aagaaatcga aaatcaaaaa gcaaaaattc gtttagaaca agagaaatta cgtgcaaata
      541 aaagaagact gcaacaatta aagaaccagc agcgcattca aaaagaaatc gaattagatc
      601 gatagacgtt aatcttgtta caaataaact actatgatat atttgatgta gtgtatttgt
      661 aacgaaggga ggggaagtaa atgcaagata aactgaaaga attgttggct attcgcgatg
      721 gaaatttatc tatgaaggaa gccaggaaat ttggaatcgc agcaaccact gtacaaagat
      781 tggtgaatca aggaaaattg atcaaagttg atcgtggtta ttatgtagag gatggtcatg
      841 gaatagatga tttattttgg cttcagcaac gattttccag gggaatcttc tctcatgaaa
      901 cgactttaga tatttaccag ctttctacga atatgccgaa attcattcac ttaacttttc
      961 cccatggcta taacgttgat cgttcaatta caaaagagca gcagttacaa tttcatttcg
     1021 tgaagaaaga agtttatgaa ctaggaaaag tagagggaac ttcctttcaa ggaaatccta
     1081 ttactatgta tgataaagag cgtacacttt gtgatatttg gaatccgaga tatgaatttg
     1141 aatatgaaat gaaattagaa gcattaaaag agtacatgga agacccattg agagatccaa
     1201 gtaaattaag agattacatg acaaaactac atgtagaaaa agaaatgaaa taccacatgc
     1261 aaagcttata ttgatggagg aaaaagatga caccgacaca atttgcagca aaaacaagaa
     1321 atttagcaaa gagtacagga ttaaatgcac agttagtgca acggcatttt atgatggatc
     1381 gtctaattga acaaatttct gaatcaaagt acaaaaatga cttcattttg aaaggcggct
     1441 ttttattagg atcaaaatat ggaatcgata gaaggacaac aattgatatc gatacgacat
     1501 ttagaaatag caaattaact gaagaaaaat tgaagagcat ttttaatgat ttaactagaa
     1561 aacccacaaa agaaggcatt gttttctcta ttcaaggaat gaaggaaaca agagaagccg
     1621 atttttatcc tggatttcaa attaaattgg tggctaattt agagaaagta cgtgtaccgt
     1681 ttaaaatgga cgtgacaaca ggagattcta tttatcctga agtagataca cactatcacc
     1741 aattaatgtt tgaagataaa aaagtggaga ttccagctta tccaacagaa caaattattg
     1801 cagaaaagct aagtgctacg ttcagctttg gcacagataa ttcgagagca aaagattact
     1861 acgacttatt taccattccg aaactagaaa atatcgatac gaaagagtta tacaaaagtg
     1921 ttcgaaatac atttacaaaa cgtggggata caaaaccgtt gtccttttat tatgaaagag
     1981 aaatggataa gatcagagga aatgactatt tggaaaagca gtgggaaaaa tatcgctcag
     2041 ttaacacgtt tgcgaattcc atttcattta cagatacagt caacgaaatt gatcacctaa
     2101 tgaaaagtgt gatcaaaatt gaaaatcaag aaagaaaacg gcagtttaaa agatcacaac
     2161 aaatgaatca agaaatggag agataaagat gattaataat gtgacattag taggacgctt
     2221 aaccaaagat cccgatttac gttatactgc aagtggcaca gcagtagcga cttttaccct
     2281 agccgtcaac cgaaatttcg cgaatcaaaa cggcaatcga gaagccgatt ttattaactg
     2341 cgtgatttgg cgcaaaccag cagaaacaat ggcgacatta gctaaaaaag gcggcttgat
     2401 cggtgttgtc ggacggattc aaacacgaac ttatgacaac cagcaaggac aacgtgtgta
     2461 tgtgactgaa gttgtagcag ataactttca actattagaa agtaaagcag cgacagagag
     2521 ccgtgcgcac gctgatcaat caaccaccag tccaagcccc actacctttg aacaacggga
     2581 tacaaacaat ggattggacg cttcacaaaa tccatttggt ggacaatcaa tcgatattag
     2641 cgatgatgat ctaccattct aagtagcatt ttctattggt tgcatttgct acggtttatg
     2701 ttataattta gtcaacaaaa agaattttca atctataacc aaaaaccact agctggcggg
     2761 ctagtggttt tcttttacgt ttctattata agaattaacg ggtaggctta ctgtctttct
     2821 tggcaaattt acaatcaagc catttgcaga tatagtgcgc ggctacttct gccatgattg
     2881 caaaaacaaa atcaaaaaga attttcaaac ctataacctc ctccccttgc cagattaggc
     2941 cggggtagca gacagcaaga ctattatagc ataattgaaa tattcaaatg attggatttt
     3001 tgctataatt ttagcgaggt gattgtgatg aacaaatatg ttggtttgct tgataaaatc
     3061 cgagtaataa aaacgcaacc gttattggtt cgctttactt tacaaacgat tcatgaatcg
     3121 attaattgtg tagttgcaga tattgaaatt atcgataaat tgctaattat ggatgatgga
     3181 aaatacaata ttgccgtcac aggtcacttc aataaacgaa accagctagt tattgctagc
     3241 atgtatgtta gaaatcccga tcagtttacg cgattgatgg gcatataaaa aaagaagagt
     3301 tgcaatccta atgtaggact gcagctcttt ttgttttaca tagaaacaag aaaaatgaaa
     3361 aggccttttt aggaaggcgc gagcgccttc tcaattgaaa aacctctctc actccaaccg
     3421 ccaccgccgt tcgagaagaa aggaagtgaa cgttgcacgt tcactaagat aaagggtctt
     3481 gcaaagcaag acaaaataga aaaaacttcc tctcaccaaa aggttcgttc ctgttcgtta
     3541 tctctttatt gatttgccag accggcaaca agttgccttt tatcaccaaa aagcgacaag
     3601 gacaagggta aatggcacgc tgcgcgccct tgtccttgtc gcttttcgtt gattcattct
     3661 ggccaacaaa tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag
     3721 gcagaatcaa tcatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc
     3781 ccaaactatc atgcaccaca tactgtcgaa tgcgattgtg gagaaagagc gaaatgtatc
     3841 aaaagctatc gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc
     3901 gattatattt tgattgatga gaaaggaaag aaacgttgat gaaaacacaa cacaaattat
     3961 tgactgtaaa agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag
     4021 cagaagcttt acttattccg cggtactgga cgacagaaac ccctttagta gaggatgcac
     4081 cgactatgct atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa
     4141 acttggaaac ttatgaaaac gaatattggt taaccgaatt agagaactaa aaaggagaaa
     4201 aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat aaaatggcac
     4261 aaaaaatgga ggatatgaca ttcctataca atgagacacg tgttccaaaa aaacattata
     4321 aggaaagatt gtcggtagct gtggaagaaa tgattgaatc aggtgtcgaa atgaatctca
     4381 ttgcgacgta ttatcgaaca ctggaagaac tgaaaaagca aaatgcaaaa tggtttttcc
     4441 aagccttact atgcttggaa gtaggcgtca aaccaagcac aatcaaacct tctgaatacc
     4501 aagctttaga actaacgtat gcgaaattta tcgaaacgaa aaaagctaag actgtttcaa
     4561 gtgaatggtt agattatttt gaaaatatca ataagtatgg cgcatgttac atcatgaagt
     4621 aatcagacgg attcaaaaag actttagttg tatggaagaa atgaagtact ttgttcaaaa
     4681 tgttgaagaa cagttatatt tggaaagcga aacgagtcaa acaaaggtca cagtcagcca
     4741 taatcgttta gatgtgtata aacgtcgtcc tgaatcatta aaaaaaggag cggagcttct
     4801 acgactagaa acagaaaaat acgtcatgaa tgtttaccta gaaaaaagtg agttggtcga
     4861 aaattttatg gactagccga gaacacccgt gattttaatc atgggatgaa tcggattcag
     4921 ttgtgaccta gctttagcta ggttaaacaa ctgacaaata taaactaaat aatagtgaaa
     4981 tgtcttgcaa taattgattt tgtagaaata catatattaa aataattgcg aggtgttttt
     5041 gtatgtcaga aattcattat ggacggggct atgtctattc tattcaatat catcttgttt
     5101 ggtgtgtaaa atatcgacat gatgttttgt atggtcaggt agatattgat gtcaaacagt
     5161 ttttgaaaca aattgctgat gataataata taaaaattat agaaatagaa tcagataaag
     5221 accatattca tttactcatt gaatgcaccc cacaacacta tattcctagt attgttaaag
     5281 tatttaaagg cgcatccgct agactgctgt ttaaaaaaca tcctgaactt aaacaactcc
     5341 tttggggtgg acatctttgg aatccaagct actttgtagc tactgttagc gaaaatacag
     5401 aagaacaaat tagaaaatat atacaaaatc agaaaaagaa atgaggtgaa tccgtatgct
     5461 acaacatagg gcttataaat ttagaatcta tcctaatcaa gaacaagaaa tattaatgac
     5521 taaaactatt ggctgttcaa gatttgtcta taattatttt ttgaatttgt ggaatcatga
     5581 atatacgact actggaaaag gattatctta taattcttgt tctgccatgc ttccacaaat
     5641 gaaaagaaat gcagagacaa tttggttaaa agaagttgac agtattgcga ttcaatcctc
     5701 attgaaaaat ctttctgatg ctttttctcg cttctttaaa aagcaaaata aacgaccaca
     5761 atttaaaagt aaaaaacatc ctatacaaag ttatacaact aaaaatgtga ataatagtat
     5821 cgaaattaga aacaatttcg taaaactacc taagttagga tttgttaaat ttgcgaaaag
     5881 tcaagagccc aaagggcgaa tcttaaatgc tacgattcga aaaaattcga gtggtaaatt
     5941 ttttgtttcc atcctgtgtg aagaagaaat agttgagttt cctaaatcta attccgctat
     6001 tggaatcgac cttggtataa ctgattttgc aatcctttct gatggtcaaa agattgataa
     6061 caataaattc acgtcaaaaa tggcaaaaaa actcaaacgt gaacaacgta agttgtcaaa
     6121 acgtgcatta ctagctaaaa agaaaggcgt caatctcttt gaagctaaaa attatcaaaa
     6181 acaaaaacga aaagtagcac gactacatga aaaagtaatg aatcaacgca atgacttttt
     6241 aaacaagttg agcacagaga ttatcaaaaa ccacgatatt atctgtatag aagacttaaa
     6301 tacaaaaggt atgttgcgta atcataaact agcaaaaagc atttctgatg tgtcttggtc
     6361 tagttttgtg actaagttac aatacaaagc taactggtac ggtcggaaaa tcatcaaagt
     6421 agataaatgg tttccatcta gtcaaatctg ttcaaattgt ggacacaaag acggcaagaa
     6481 atctctagaa attcgagaat ggacttgtcc tgtttgtcat gctcatcatg accgagatat
     6541 caatgctagt atcaatattt tgaccgaagg tctaagatta catgtcatgg gattagctta
     6601 gatccaatca tcaaaaaccg taggaactac ggggatagct tggtaaataa gagaaaccgc
     6661 tgtgagtaaa gaaatacgct tgcaagtatg ctctattccc aagaatctcg tgactttagt
     6721 catgagaggt tcaaggattc atggaatgtt aatctaattt aatagaaaag gataattaag
     6781 tatatacgtt ttttcttatg tatgttatac tatgtatata cagaaagagg tgtctactat
     6841 ggaaatgtta cctataaaaa aatggggaaa tagtaatggc cttagattgc caaagtatat
     6901 tatggaatat cttggaattc atacagaaga caaagtgaag ataatacaag aagaagtaaa
     6961 cggtcagaag cggctaatta tcgaagcggc taatatagaa aatgaattaa caattgaaca
     7021 gttatttgaa aattacactg atgaaagaaa tcatgtgacg attcaaaatt taggtgaagc
     7081 agtaggtaat gaaaaatggt gagaaaacct agacaaggcg atattctatt attgaataca
     7141 gcacctcgat ctggacacga acagacaggt aaaagacctt atattgtttt aagtcatgat
     7201 attattgcgg attatagtaa cgttgttaca gttgctccaa tttctagtac aactagaaac
     7261 tatccgctat atgtaaatat aaactcagaa tatgaaatga agacaacagg aaaagtatta
     7321 ttagatcaac taacgacaat tgattatgaa gccagagagt gtattttttt ggaaaaagcg
     7381 catgatagtt tagttgagga gttattgatg aaagttagaa cagtttttca aaaagtaagc
     7441 aaataaaata gaaacagcag catgatcaac tattcgtgat tgaccatgct gtcttttttt
     7501 attctatata cggtttgtct cgtaacattg tagtcttttg caatcttagc gatcgcaaca
     7561 ccttttttta gatcctcaac gatgttttta taaacaagac gacgttgggg atcttttgca
     7621 ttggcactgt atagcttagg acgtccttta taaacaccgt tcgcttttgc aatcttaatg
     7681 ccttgtgcct gacgtcgttt agattcggta cgttcttgtt cagcgatcat ggccaaaatt
     7741 tgaatgatca aatctttaat gaatttatcc aggagaggat tgccaattgc ttcggccatg
     7801 atcggtagac ttgtgatgat cagctgcaca tttttcttct tcaagtaatt gactgaagcg
     7861 atgatctcgt cgtaatttct tccaagtcga tcaatagctt ccacaataaa aatatcttga
     7921 tctcggacga aatccagtgc ttcttgaaaa acaggtcgat gagtaatcgt tgcgccagat
     7981 tgtttctcaa tgaaaattct ctctgcaccg aattttttca tttcttcaat ctgccgttgt
     8041 tcattttgat cgatggatga gacacgtatg tatgcaactc tcaaaatttt tacctacttt
     8101 ctgcaactat ttaaaaaaca ccctaatcat acacgagaaa accagatttt tcaatgtcgc
     8161 ggtcgtgtct agttagggta taccttatat agacaaaaac taatgatgga ggaaatagta
     8221 tgtgtcactt ttctttttaa atggcaatat tttttgtaaa taaatgtcaa tcaagaaaat
     8281 ttaaacgatt atgacattaa aaatatattt tatgaatttt ctagtatata acttgattta
     8341 tctgttaaga tttattaaga aaacgttttc ttatttttga tttcgaggtg atagacaatg
     8401 aaaaataagt ttattttatc tttaggtatt ttaactattg gaattagtgt aactggaact
     8461 acaattccta catttgctga tagtacaaat gaaccaacta ctgtagtaga taataaccaa
     8521 gaattaactc ctttagatag gaacggaata gccattggta acccaactaa cgacttaact
     8581 gttactgaaa attatttaat agtttctcca ttacttgctc gagcagcttc taaaacgata
     8641 cgagtgacag gaacgatgat ttttgataaa gttggttggc cttctagacc tcctcaatca
     8701 cggaattgga aagaaaaaag aaatggttat tggtactatg gaaaattgta tttacaaagt
     8761 tataaatcag ctggaaacaa ttggattgcg acttattcag gaaccttaac tagaaagtag
     8821 ggatttttta tgccagaatt tgtgaacaca ccaaattttt atcaagatag cgatattcta
     8881 agtaaaatta atttaccgaa agaagaatca gctttacaag ttcagcgaac tttacaggag
     8941 acacaaaaaa ttcaaaaatc aatttctaat ctagaagatt ctgaagaaaa aagaaaaaaa
     9001 agagaccaaa aaacatatca aaaagaaaaa taatgatttt aaaaaaagag tgtctagtcg
     9061 acattctttt tttctaattg aaagtgttca taaaatcacc catttctgga cactttcttt
     9121 ttttgcttta tttttcaaaa aaacaattca tttcatgttc ataaacccat aacaatatct
     9181 atgttcagtt aaactatatg gataaagtta tgttacaata aaattaatga aggagtgatt
     9241 tttttgaaaa taggatacgc ccgggtatct actggtttac aaaatttgga tttacaagaa
     9301 gacagcctaa ataaatttgg ttgtgaaaaa atttttactg atcatatgag tggggcaaaa
     9361 agtaatcgac caggattaga aatggccatt gattttgttc gctctggcga tacacttgtc
     9421 gtttggcgct tagatcgttt aggtagaaat atggaagatt tgatttcaat cgtcaatcga
     9481 ctgaatgagc gtggtgtgag ttttcatagt attcaagaaa atattacgat ggacaaatca
     9541 agttctacag gacagctcat gtttcatttg tttgcggcat ttgcagaatt tgagcgtaat
     9601 ttgatcctgg aacgatccgc agcaggacga gcagctgctc gtgcaagagg acggtttggt
     9661 ggtcgtcctg aaaaattgtc tgaacaagat ttggaattac tgaagacttt agtggatagc
     9721 ggtacaccta ttaagactat tgcggaacgg tggaacgtct caagaaccac catttatcgt
     9781 tatttggcaa aaatggagga gaaaaatgga aagacaaatt ctcattagtt tttgtcattt
     9841 aatgctgaaa atttttgcca tttatctaga aaagtgacaa tagtatgaga attttttgta
     9901 agtgtctact gataacttat tctcaaatat ttagctattt cttctttaca acatcgaaca
     9961 tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc aaaagagcca
    10021 gtaaatgatt actttttaat cgatatgaaa agcttttacg caagtgtcga atgtatagaa
    10081 agaaatttag atccattaac aacagaactt gttgttatga gtcgatctga taatactggt
    10141 tcaggattga tattagcttc ttctcctgaa gcaaaaaagc ggtatggtat tacaaatgtg
    10201 agtagaccac gtgacttacc acaaccattt cctaaaacac tacacgttgt tccaccacgt
    10261 atgaacctat atatcaagcg aaatatgcag gtaaataata ttttcagaag atatgtggct
    10321 gatgaagatc tactgattta ctcgatcgat gaatcgattt taaaagtgac aaaatcactg
    10381 aatcttttta cgactgaaga aacacgaagt cagcgaagga agaagctcgc tcaaatgatc
    10441 caagaacgta ttaaagaaga gttaggtttg attgctacgg taggcgtcgg cgataatccc
    10501 cttttggcta aattagcctt agacaatgaa gcaaagcata atgaaggatt tattgcggaa
    10561 tggacgtacg aaaacgttcc tgagaaagta tggaatattc ccgaaatgac ggacttttgg
    10621 ggaattggtt cgcgaatgaa aaaaaggctc aaccaaatgg gaattttgag cattagagac
    10681 cttgctaact ggaatcctta tacgattaag aatagattag gtgtgattgg attacagctg
    10741 tacttccatg ctaatgggat cgatcgaaca gatatagcaa tcccaccaga accgacaaag
    10801 gaaaaatcat atggaaattc acaagtgtta ccacgagatt atactagaag aaatgaaatc
    10861 gagctggtgg taaaagaaat ggcggaacaa gtagcgatac gcattaggca gcataactgt
    10921 aaaacaggtt gtgtccattt acacattggc acgtcgatct tagaaacgag accagggttt
    10981 tcacaccaga tgaagatccc tatcacagat aatacaaagg aattgcagaa ttattgtctt
    11041 ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat aacctatagc
    11101 aagcttgtgt acaccgattc gcttcagctg gatttattta gtgatccaca aaagcaaatt
    11161 aacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg ttttacgtcg
    11221 attgtacatg cttcttcaat gttagaaagc gctagaagca ttactagaag cacacttgtt
    11281 ggtggtcatg cgggcggaaa tgggggaatt aaaaatgatt gattacaatg atcgtggacg
    11341 tttaaagtgg gcagggtttt atttatctga tcatactgaa gaaattgatg ccgacaatga
    11401 acaacgaacc agtcaaaatt tagcaaaa
//
LOCUS       DARPZJ010000073        11275 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.076, whole genome shotgun sequence.
ACCESSION   DARPZJ010000073 DARPZJ010000000
VERSION     DARPZJ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.076"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(51..560)
                     /locus_tag="SLE23_002424"
     CDS             complement(51..560)
                     /locus_tag="SLE23_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469295.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(550..1275)
                     /locus_tag="SLE23_002425"
     CDS             complement(550..1275)
                     /locus_tag="SLE23_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469296.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(1498..3618)
                     /locus_tag="SLE23_002426"
     CDS             complement(1498..3618)
                     /locus_tag="SLE23_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEI8469297.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            3848..5026
                     /locus_tag="SLE23_002427"
     CDS             3848..5026
                     /locus_tag="SLE23_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEI8469298.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            5042..5800
                     /gene="aroD"
                     /locus_tag="SLE23_002428"
     CDS             5042..5800
                     /gene="aroD"
                     /locus_tag="SLE23_002428"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEI8469299.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            5823..6308
                     /gene="ybaK"
                     /locus_tag="SLE23_002429"
     CDS             5823..6308
                     /gene="ybaK"
                     /locus_tag="SLE23_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HEI8469300.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(6379..7632)
                     /locus_tag="SLE23_002430"
     CDS             complement(6379..7632)
                     /locus_tag="SLE23_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEI8469301.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            7749..9098
                     /gene="gdhA"
                     /locus_tag="SLE23_002431"
     CDS             7749..9098
                     /gene="gdhA"
                     /locus_tag="SLE23_002431"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEI8469302.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            9210..10556
                     /locus_tag="SLE23_002432"
     CDS             9210..10556
                     /locus_tag="SLE23_002432"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEI8469303.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(10864..11250)
                     /locus_tag="SLE23_002433"
     CDS             complement(10864..11250)
                     /locus_tag="SLE23_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8469304.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3666 a         2021 c         2292 g         3296 t
ORIGIN      
        1 atcatgaatc gatcttctat accgcttgtt tttactataa aatgattgat ttagcccgcg
       61 ggctctaaac gatcaatata aggactttga gcaatagtag catcatgagt aaagagtaag
      121 ataccttgat tttcttcatg agctaaataa gaaagcaagt ggagtagctc ttggatctcc
      181 aatacactaa gttcatcaaa tgtatcttca ataacaatat tgtttcgctt ggaaagcaag
      241 gcatgaagta attgcagctt tactttttca aaagacgtca actcagctgc cgcacaatta
      301 agcaaggaag gagagatatc aagtttttct tgataggcca aacgatcttg tttgatttct
      361 ttttccggta catccaacag gacatggtct ttaagattca gataaggaaa catcggccaa
      421 tttttttgga tgatcgcaaa attatccagt tttgcaacaa gaacctcttt tttcaagtgc
      481 tccaatattt tatgctgttt ttcgagagga cacaaaataa cggtcaagtg ttcagcatga
      541 atcaaatatt caggtttcat tacgtccagg cctcctactt tgcaaatgat ggataaaaaa
      601 agtgaaaggg aatagactaa gaatgagaca gcatccactg agcccaataa gagtttgggc
      661 aaatccctta agtatatctg tgaaaaaaag atcattttgg aaatcgatgg taaaaaaagt
      721 ctgttgatcc atcggaattg taagtccgct taccgaagtc aagatatcac ggatatctgg
      781 cagttcagta gtctttaaga caagaaaatt gatcctttga agaagcgctt cataaactga
      841 ctggaagctt acgatccaca ataaaaccaa gatacaacaa agaaagagag gaaagaacag
      901 ctgccagaaa ataaaaagga ataatttggt tttagaaaga ccagtcaggt gccaattgat
      961 caattcctgc ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa ggaaggcaaa
     1021 tagaaaaaat aaactgaata tgccttttat ataaaatcgg ctagctaatt ctaaagccgg
     1081 aagaagctct gtagatgcag aagcgccaat aaatgaaagc cgatcttgga cttgattggc
     1141 taaagccgat tgcaaatggt aaagagtcag gcatgctatc aataaaaaag cagaaaagct
     1201 tgaaaataaa caatagagta ttgtctgctt tttgtaataa attaatcgag cagtagcata
     1261 gcggattatt ttcatacttt tcacctctat aaaaagtata gaaaatgaat atgaataaag
     1321 tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa aatattttgt aaaaagcaag
     1381 aggttgtgaa gaagctgccc tattctatta ccgtagatgc aagcttttga acactgttta
     1441 ttcgaaaaga ggagcagcga caataatttt gtcgctgctc cttttaaatt tattttatca
     1501 ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac gtttgcgttt tataaagatc
     1561 aacagttgat tgtccgttgt gttcactaaa gacactagtt gacttgtcac caagagattt
     1621 ttcagcttct tttaatttct ctaagccatt cttgtagtca taatcactgg tatcaattgg
     1681 gtctaatcca ctattcgtat agaaccgaag aagatcacca ttattgattt ggtcagaaac
     1741 agctaactgt ttatcaactt tttctttcag tgaatcaatt tcattctgta cttcctcagt
     1801 aggttcagta atagcttcac cagtttcgtt actatagatc gtaccaccgt agtaagtata
     1861 ttttggtgta acaaaatcac catcacggaa agaaacaagc tgttcatgat ctttcgagaa
     1921 tagatcttgt cctaactgaa tataattttt tgtatctaca cctagtaagt gaagtaatgt
     1981 aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt ccgccctgtg tttgtccagg
     2041 gatatggatc atataaggga cacgctgcat ttgtgcattg tcgtagtttg tccaagtaga
     2101 acttgttttt ccaactaatt cagctagatt tttatttctt gaattcgaga caccgtaatg
     2161 gtcaccgtaa aggacgatga ctgaattatc atacaagccg ctttctttca aataattgaa
     2221 gaattcttgt acggcggtat ctaaataatt ggctgtcgca aagtaaccgt tgatcgtttc
     2281 atcatttgta ttggctaacg ggaatcctgc ttcgtcattg gtgaattttg aataaggata
     2341 atggttagat acagcaatga attttgaata aaatggttgt tgcagacgtt ccaagtattg
     2401 tacggattgt tggaaaaatg gtttatcatg caacccgtat tggaacgaat tgtcatcatt
     2461 aacatcataa taagaagaat caaagaaata atcatatcct aaattcttgt atgtctcgtt
     2521 tcgattccag aatgtaccag cgttcccatg gaataccgca ctaatgtaac cttgtgtttg
     2581 acttaaaata tcaggtgcag cttggaaagt attttttccg cctaattgtg tgaacaagga
     2641 gccttgattc aagccaaaca atgaattttc catcagcgtt tccgcatcgc ttgtttttcc
     2701 tgcttttact tgatggaaaa agttgtcaaa actgaacgtg ctgttgctgt ggtaaagact
     2761 attgatgaaa ggtgtaactt catgctggag accattctca tctgtcaatt tataatcgat
     2821 caggaattgc tggaagcttt ctaaatggat ataaatcaca ttttttcctc tagcgagccc
     2881 gaacaaatcg tcatttggtg ctgcataatg ttcttttaca taattttcta cttctttcat
     2941 atcattggga cttgcttctg cccgcacttg gtttgtctgg taagtttgaa caccgtcata
     3001 aaccatgaaa gcattcaagc caagatattt gaccaaataa tcacgagaga atgttcgagt
     3061 cagcaattct ggacgatcag cttccgccat aaaaagattt cctgagaaaa tcataactgc
     3121 taatgtagag atcgcaaaag ccattcttgc tcggatcggg cgagggtcca acttgatttt
     3181 ttttgcaatc agcagaacag tcaagataat aaaatcgatc caatagatca catcatatgg
     3241 gcgaaacagt cgaatggcac tttctcccag accactcgct actttcccag cacctaaaat
     3301 cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa gtgacattcg aaaaaacaag
     3361 caatgtcaaa agaaaataaa tgaccatcat cgtgatataa gcaactctag ggcgtctgat
     3421 ataaagagca attccaagta ataacaatgt agttgcaata gggttgataa acaagataaa
     3481 gtattgaatg ccactttcga ttccgagatg gaaatcaact aaataggcaa aaatcgtttt
     3541 caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc ctcttattca aaaaggcagg
     3601 tgtttttata catttcaaga taatcttcct ttctgcactt cttaatcaca gaagtgtcct
     3661 gaaaccatgt tacacagctc acttattctc atttatttta ctagtatgac aatatagtgt
     3721 caattgaaac cagaagttta tgctgtttca ttaaggtttt ctttaagctt catgaaaaaa
     3781 tgagcagtaa gacaagtcct atgttttttg ttatacttgg gaagagaaag ctaaagcagg
     3841 tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat cgattgaaaa aaggatatcc
     3901 actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa accacgcaat gggtggaatt
     3961 agttgattcg caaaaccaat ttatcgcaaa aggatatcta ggaaagcaga ataagggaat
     4021 cggttgggta ttgagccagc agaacatccc atttgatcaa tctttttttg aagaattttt
     4081 tgtgaagtca aaagaaaaaa gaactttctt tttttcagat gattctacta ccgcttttcg
     4141 tatattcaat ggagaaggag acgggatcgg cggtctgatt gttgattatt atgcaggtta
     4201 tgctgttttt tcttggtata acgaaacgtt atatgcacat cgtgaattat tgattcaagc
     4261 ttttcgtgaa atctacccgg aaatcatagg aggctatgag aaaattcgat ttgaatcagt
     4321 aaatctgcct gagagccagt tcatttacgg aaaagaggca ccggaaccct tgatcgtaaa
     4381 agaaaacgga gtaaaatttg ccgtttattt aaatgaagga ttaatgactg ggatcttttt
     4441 agaccaaaaa gaagtacggg gatcattagc agaaggtttc gcttctggga aaacagtttt
     4501 gaacatgttt agttataccg gcgccttttc tgttgctgcc gcaatgggag gggcaatcga
     4561 aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa acacaggaac agtttgaagt
     4621 gaatggtttg gatgtcgatc agcaaaaaat cattgttatg gacgtattcg agtatttcaa
     4681 atacgccaaa agaaaacaat ttttatatga catgattgta ttggatccac caagttttgc
     4741 cagaaataag aaaaaagtct ttcgcgtagc aaaagattat ggggaactgg tcaaggatag
     4801 tctggatatt ttagcagaag acgggatact tattgcgtct acaaatgctg cgaatgtctc
     4861 gatagaacaa ttccaaacaa tgattgaaga ggaattccat gccaaaaatg tttcttttga
     4921 acaacttgct ttatatcgtc tgccaaaaga tttccagacg acggatacct ttttagaagg
     4981 caattatctg aaagtgtttg tttatcaaat taaaaataac cattagaagg agcgatgcag
     5041 aatggttcgg gtaaagggat tgaatatagg aagcggtaga ccaaagattt gtgcgcctct
     5101 tatcggggcc gtccgagagg aagtattacg tgaagcagtt cttgcacgtg aagcaggggc
     5161 cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt ttttcttttg atgaagtagc
     5221 agaaacattg gttcttatcc atgagatgct tgatggactg ccgttattat ttacgtttcg
     5281 taccttagct gaaggcggag aacaagacat atcgatccgt cagtatcgcg acctttatga
     5341 acatgtgata cacacaggat tagtagatat ggtcgatatc gagttgttca aagtagaaag
     5401 tctaggaaaa agactgatag aggaaatcaa gtctttaaac attcctttaa ttatcagtag
     5461 tcatgatttt aaagaaacac cagcagaccc tgtcttgctt taccgattga atgttatgga
     5521 acattttgga gccgatatcg gaaaactggc agtaactccc aataatgaac gagatgtttt
     5581 gcggttgatg gagttgacta gacgggcaaa tgcttttgtc tccatgccta ttattacgat
     5641 gtccatggga aatcttggta aaatttctcg tctggttggc ggaacgacgg gttccgttat
     5701 gacatttggt tccttaagca gcgattctac ttctgctcca ggacaattac cggtcaaagc
     5761 attgaagcaa attattcaat tattaaatga accgttgtag aacaagtttg aggtgatatt
     5821 ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg tatggtcgaa caaaaaaaga
     5881 ttccctatac agagcacgaa tatgagtggg acgaaagcca cctaagtgcg tcatcggtcg
     5941 ctgaacagct tccagaaagc caatctcgta tatttaaaac actggttgct gtgggcaatg
     6001 tgacggggcc tcttgttgct gtgataccgg gagaagccga attgaatcta aaaaaattag
     6061 caaaagtttc agggaataaa aaagtagaaa tgctccattt aaaagatttg gaagcaacga
     6121 ccggatacat acgtggtggc tgctcgccta taggtatgaa aaaactattt cctacttatt
     6181 tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc ggctggcaga agagggctac
     6241 agatggagtt agcacctcaa gatatctgtg cattaacgag cggacaattt gcagatataa
     6301 aacaataaat catacgtata aaagaaagaa ggaggccggg atgttgtttg tccagtctcc
     6361 ttctttcttt tttatacatt atgctctttg cccggcattc attcctgcta catgccctgt
     6421 agcgaaagcc gctgtgatat taaagccgcc agtataacca ttgacatcca gtaattctcc
     6481 cgcaaaatac agaccatcaa tgattttact ctccaatgtt ttaggataaa tttcctttag
     6541 agaaacccct ccgccagtta caaatgattt ctcaatagga aaagttttgt tgattgatag
     6601 cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt ttttgagagg cttgttgtcc
     6661 tgtcagatga tccatttcaa gccgctcaag aaagaaaact aacaatcgct caggcaatat
     6721 accatgccaa gcattgacca agttcttttt ggttgcttta cttttttctg tcaatatatg
     6781 aataagctct tgtttggttt gtgtagggaa acaatccaga gaaagtgtca ctggttctcc
     6841 cgttttctct aattctttat tgacaaaact tgaacaacgc agtgcagccg gaccagaaat
     6901 accgaaatgg gtgaaaagta aatccatcgt atgttcagtc aatacacgac cttttttatt
     6961 taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga agtgttttct cctgaatata
     7021 cggttcatcc gatatcaagg gggactctgt cgcataaaga ggcgtcaccg tgtgacccac
     7081 tcgcttcacg atcttgtacc catctccagt agaaccagta gatggataag tccgtccacc
     7141 agttgttaag ataatggcag gagcatggaa ctcttcgaat tccgtgcgta taccgtaaat
     7201 tttatgttct ttgtggatca atttctctac tcgagtagag aatagaagcg tcacatctag
     7261 ttctttcaga cgattgagca atgcttcgat aatcgttttt gatttatttg ttacaggaaa
     7321 catccgtcca tgatcctctt cttttaaatg tacgccttgt gattcaaaga agttcatgat
     7381 atcgaaatta ttccattgcg caaacgtact atataaaaac tttccatttc caggaatatg
     7441 tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg caccgaccac cacctgtcat
     7501 cagtagtttt tttcctgctt ttttgttttt ttcgatcaag agtacgcgtg cgccttgttc
     7561 agctgcactg atcgctgcca tcatcccgct tgttccagcg ccgactacga tcacatcata
     7621 cagtttttcc attccctcac ctcaaggaaa gtgtagcata tctgaagaaa gaaaacagaa
     7681 aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga gggaagataa gcaaaggagc
     7741 gtggaacgat gacaaacgca acagaatatg ttcaagcaat tcaagaaaag ctacatcaaa
     7801 aggatcaagg gcaagaagaa tttttacaag caatcgatga attcatgccc acggttatgt
     7861 cttttttgga cactcatccc gaatatatcg aaaagaatat cttagaactt ttaacggaac
     7921 cagaaagagt tattcaattt cgagtgcctt ggcaagatga tgaaggaaac tggcgagtaa
     7981 atagagggta ccgtatccaa tacaactcag ctatcggccc ttataaaggt ggattgcgct
     8041 tccatcctag tgtcaatcta agtatcttga aatttttggc ttttgaacag attttcaaga
     8101 atagtttaac cggtctgcca atcggtggag gaaaaggcgg aagtgacttc gatcctaaag
     8161 gaaaatctga taatgagatc atgcgttttt gtcaaagttt catgctggaa ttgtcaaaac
     8221 atatcggccc atcgattgat gttcctgcgg gagatatcgg tgtaggagct agagaaatcg
     8281 gctatttgtt cggcgaatat aaacgattga aaaaatatga tactggtgtg ttgacaggta
     8341 aacctttgga tttttgggga agtaagatac gtacggaagc tactggttat ggattagtgt
     8401 attatgtcaa acatctattg aacgaagaaa aagattcatt taatcaaaaa acagtttttg
     8461 tttccggaag cgggaatgta gccatttatg caatcgaaaa agtgcaagag ctaggcggga
     8521 aagttgttac atgttcagat tctagcgggt acatctatga tccagaagga atagatgtga
     8581 aactattgaa agaagtcaaa gaaatcaata gacaacgttt gacggaatac gcaaaccaac
     8641 gtccttctgc tatttatcat gctggagaat ctgtttggac attgaaagaa aaagcggata
     8701 tcgctttgcc atgtgctact caaaatgaaa tagacgaaag cttggccgaa atcttagtag
     8761 aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc atgtacagta aaagctgttt
     8821 ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa agctgctaat gctggaggag
     8881 tagcagtatc tgctttagaa atgagtcaga acgtccagcg attgacttgg gaaagagagc
     8941 aagtggatga gcagctggat caaatcatgg aaacgattta ccatacgtgt cgccaaacag
     9001 cagccgagta cggcgacgaa aaaaatctgc ttcttggagc aaatgttgct ggatttgaaa
     9061 aagttgccaa agcaatggca gcagaaggtt tagtttgaaa aatgaaactt tcttggaaat
     9121 attgtcagca ttttgtttat ttgcttgaaa aataataaaa aaaaacgtaa agtattacct
     9181 gtagagtaaa cctataagga ggagaacaaa tggcacacat tcattttgac tattcaaaag
     9241 tagcaccgtt tgtcaacgaa caagagttag ggtacatgca aagccaagta acagcagccc
     9301 acaacgaatt acgggaaggt actggcgcag gaagcgactt ccgcggctgg atcgatttac
     9361 caacgaacta tgacaaagaa gaatttgcac gtatcaaaga agcagctaaa aaaatccaat
     9421 ctgattctga agtattagtt gttatcggta tcggtggttc ttatttaggc gctcgtgcag
     9481 cgatcgactt cttgaatcac acattcttca atttattaga tagcaacaca agaaaagcac
     9541 cacaaatctt ctttgccgga aattcaatca gctcaacata tattgctgac ttgatcgaag
     9601 taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa atctggaaca actactgaac
     9661 cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa gaaatatgga caagaagaag
     9721 caaacaaacg tatctacgct acaacagata aagcaaaagg tgcagttaaa gtagaagcag
     9781 atgcagaagg ttgggaaact ttcgtgattc ctgatgacat cggcggacgt ttctctgtat
     9841 taactgctgt tggtttgtta ccaatcgctg ttagtggtgc agatatcgat gcattgatgc
     9901 aaggtgccgc tgatgcaagc aaagcatact caagcgacaa actagaagaa aacgaagctt
     9961 accaatacgc agcaatgcgc aacattcttt accgtaaagg caaagtaact gagttgttga
    10021 tcaactatga accaggaatg caatacttct cagaatggtg gaaacaattg tatggtgaat
    10081 ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc aaacttctca actgatttgc
    10141 actctttagg acaattcatc caagaaggac gtcgcaatat ttttgaaaca gttgtgaagg
    10201 ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc agaagattta gacggtctag
    10261 gctacttgca aggaaaagaa gtggacttcg taaatacaaa agcatttgaa ggaacattgc
    10321 ttgctcatac agacggtgac gtgcctaact tgctagtcaa aattccagaa atggatgctt
    10381 atacattggg ttatacaatg tacttctttg aaattgctgt aggtatttca ggttacttga
    10441 atggaatcaa cccattcgac caaccaggtg tagaagctta caagaaaaac atgttcgcac
    10501 ttctaggcaa accaggcttt gaagatcttg ctaaagaatt gaacgaacgc ctgtaagata
    10561 agggtttttc gctagattta aataatcagt gatagaaaca tgttcgcttt aaaatgaaaa
    10621 ctggtaccca tttaggtact caaacatact gcatcgttta ttcagaataa ggggctgtga
    10681 caagacgttt gtcacagtcc cttgtttgta tagaaatcga ttgattgcct tgctctttag
    10741 tttgttttag gactttaaga acagtgaggc tgacttcgaa ggttaattct gtttttttgt
    10801 tttctagaat cagtaagcaa aaaagcactc acttcgagtg cttttttgcg atatattctt
    10861 agcttaagat aggcctaatt tttcttttac agatgagggt accttatcgc tggtaattac
    10921 ttttttctct atgatccgct tttcgcttgc tttcaactgc aagatcgttc cttcggggta
    10981 agcagaacca ttggcagagt caccagaagt aatgacatcg aaatctaact gtcttttttc
    11041 accgttttca gcataagcat ctacgttgta tttaaaacct cttccaatta cttccccatt
    11101 atctgctttg atatcagttt ctgcaggcat tggagctttg actaccgcat aataatcttt
    11161 acctacataa gtagactgat agtagtccca acctttccat cctataaaag caatcaatat
    11221 gataacgatc aaccctaaaa tttttttcat gaaagatctc cttttttatt tttat
//
LOCUS       DARPZJ010000074        11255 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.077, whole genome shotgun sequence.
ACCESSION   DARPZJ010000074 DARPZJ010000000
VERSION     DARPZJ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.077"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="SLE23_002434"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="SLE23_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEI8469305.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="SLE23_002435"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="SLE23_002435"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEI8469306.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="SLE23_002436"
     CDS             complement(2169..2906)
                     /locus_tag="SLE23_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEI8469307.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="SLE23_002437"
     CDS             complement(2997..3524)
                     /locus_tag="SLE23_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469308.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="SLE23_002438"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="SLE23_002438"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HEI8469309.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="SLE23_002439"
     CDS             complement(4401..4886)
                     /locus_tag="SLE23_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HEI8469310.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="SLE23_002440"
     CDS             complement(5039..5236)
                     /locus_tag="SLE23_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469311.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="SLE23_002441"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="SLE23_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HEI8469312.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="SLE23_002442"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="SLE23_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HEI8469313.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="SLE23_002443"
     CDS             9211..9423
                     /locus_tag="SLE23_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEI8469314.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="SLE23_002444"
     CDS             9425..11104
                     /locus_tag="SLE23_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEI8469315.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3266 a         2429 c         1971 g         3589 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaata
//
LOCUS       DARPZJ010000075        10748 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.078, whole genome shotgun sequence.
ACCESSION   DARPZJ010000075 DARPZJ010000000
VERSION     DARPZJ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.078"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     regulatory      92..136
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            160..1134
                     /locus_tag="SLE23_002445"
     CDS             160..1134
                     /locus_tag="SLE23_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HEI8469316.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     gene            1139..1714
                     /locus_tag="SLE23_002446"
     CDS             1139..1714
                     /locus_tag="SLE23_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8469317.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(1781..2920)
                     /locus_tag="SLE23_002447"
     CDS             complement(1781..2920)
                     /locus_tag="SLE23_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HEI8469318.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(3319..4617)
                     /gene="eno"
                     /locus_tag="SLE23_002448"
     CDS             complement(3319..4617)
                     /gene="eno"
                     /locus_tag="SLE23_002448"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEI8469319.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(4733..5488)
                     /locus_tag="SLE23_002449"
     CDS             complement(4733..5488)
                     /locus_tag="SLE23_002449"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEI8469320.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(5592..6782)
                     /locus_tag="SLE23_002450"
     CDS             complement(5592..6782)
                     /locus_tag="SLE23_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEI8469321.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(6892..7893)
                     /gene="gap"
                     /locus_tag="SLE23_002451"
     CDS             complement(6892..7893)
                     /gene="gap"
                     /locus_tag="SLE23_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEI8469322.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(7934..9025)
                     /locus_tag="SLE23_002452"
     CDS             complement(7934..9025)
                     /locus_tag="SLE23_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HEI8469323.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(9174..10508)
                     /gene="rpoN"
                     /locus_tag="SLE23_002453"
     CDS             complement(9174..10508)
                     /gene="rpoN"
                     /locus_tag="SLE23_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HEI8469324.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            10568..10639
                     /locus_tag="SLE23_002454"
     tRNA            10568..10639
                     /locus_tag="SLE23_002454"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10601..10603,aa:Arg,seq:ccg)
BASE COUNT         2856 a         2209 c         2034 g         3649 t
ORIGIN      
        1 ttctcctcaa tagatttact tgtaagagag catttacatt cgcaataaaa gccagtatac
       61 taatttcgtg cattataatc aagacgctcg tcttggactg gttcggaaac ttcccagaat
      121 aaaaaactaa gtatctctaa agaaaggaga ttggaaataa tgcgaaaagt aattattgat
      181 tgcgatccag ggatcgacga cactttagct ttatcattag ctgtcaaatc ccctgatatc
      241 gaagtagttg ctattaccgt agtttgtggg aatgtccctg cagatatagg tacgcagaat
      301 gtgctgaaat gcctggaacg ctgtgatcgt ttagacattc ctgtttatca aggaatggaa
      361 aaacctttga agcaaccttt catcagtgca caagacactc atggtatgga tggtttaggg
      421 gaaacaaatt tcccgatgat cttgagaaaa caggcagaac ctctccatgc cgttgatttt
      481 ttggctgatt atttcaaaga aaagacaaat acatcagtca ttgctttggg tcctttgacc
      541 aatatcgctt ctgctttgaa agtcaaccca aatattggga aacatatgga acgttttgtc
      601 tcgatgggtg gaacttacaa aagccatggt aactgttcgc cagttgctga atacaattac
      661 tggtgtgatc ctgaagcagc ttcttatgta ttcgagaatc tcaaacaaac gatagaaatg
      721 gttgggttag atgtgacaag agaaatcgtc ttgacaccga ctatcctcga atactgctgt
      781 caaatgaatc ctgaagaggg agagtatcta aaagcgatca ctcgttttta ttttgacttc
      841 cactggaaac aagaaagaat tttaggatgt gtcatcaatg atccgttagc tgttgcttat
      901 tttatcgagg aggccatctg tgaaggtttc aaaagcttca ctgctgtgga aactcaagga
      961 ataagtcgtg gacaaacatt ggttgatcgt tatgaatttt ggcagaaacc tgctaacagt
     1021 aaaattatga caaaagtaga tactcgtctt tttttccgaa agtttttaac cgttctttta
     1081 aatgcacaag aagaaacgat tatgaaagat ttggaaaggt taaagatggg ctaacaaaat
     1141 gaataaaaac aaaatggcaa ctcgcgtact tacagtgatg gctttgtgta ttgggatcaa
     1201 ttatattgga ggaacgattg ctttatggct tcgtttgcca atctatctcg attctatcgg
     1261 aacgattttt gctggtgcat tgcttgggcc tgtacctgga atgctgacag gattgtccag
     1321 cggtatttta agtggagtga ctacagatat tttttctctg tattattcgc caatccaaat
     1381 tctcacaggc ttgcttgctg gattgatttt gccaagatat ctcggcaaag ataaaaacag
     1441 cttgaaactg ttattactcg ctttgatttt gtcggtacct ggaacgatcg tttcttcgat
     1501 cattaccgtt cagttatttg gcgggatcac ctcctcagga tccagtatga tcgttcagct
     1561 attacatggg ttaggtttaa gtcagacaac aagtgtgatc ttggtacagg caggtacaga
     1621 ctaccttgat cgtttgttgt ctatcgtcgt tgtttcatta gtcatcacta tgttgccaca
     1681 acgcttgata tattcaaaaa gaaaaatagg ctgaataaac agagctggat tagcaaaata
     1741 atgctaatct ggctctgttt tttcatttat taaaaaaatc ttacgctaag taggataaaa
     1801 taattccttg atatttttcg atcatatcca aataattatc gatttcaaca tactcatcta
     1861 cttgatgagg caaagtaacg acaccaggcc caaagacgac aaagtcgaag gaatggttag
     1921 ctttcgtaaa ttcggctgca tccgttgttg ctgccgctcc aactaaaggt aatggctggc
     1981 tgaattgttg ctgaatgcaa tgaatcaaag gagaatctgg atcagctttg acaggtattt
     2041 tgttgtaatc gatcatcaat tccaaatgat agtctgtctc ttgattcaat tcattgacga
     2101 ttgattgcag caatgcaatg attttatcat ttgggtattc tggaatcgat cgaatgttcc
     2161 cttggagctg cgcatggctt gggatgctgt tgacttgatt cccgccactg atcaatgtaa
     2221 cattatggat tgtttttcct aggacaggat tctcgattgt ttcagcgagg tgattcattt
     2281 cagcatttgc tttcgtaatg aattcattta ggtgattgat tgcattataa ccttggtctg
     2341 gcatagagct atgcgcttct tttccgtgcg aggtgactgt atagttgatt gatcccatgt
     2401 gcgtatacat caaactgtaa ttggttggct ctccgatgat caaggcatct aagtcatcta
     2461 catagcctgc tttcgtgagc tgttccccac ctagttcacc cacttcttct ccgacagtgg
     2521 ctaataattt gactgttccg ttaaatggtt ttcctgactc tttcagttcg atcatggcaa
     2581 tcaccattgc tgccaagcca ctcttcatat ctgtagcacc acgtccgtac aaacggttcc
     2641 catggatttc tgctgcaaag ggtgcatagg tccaagacga ttcatcacca gccgccacga
     2701 catccatatg cccagatagg cctaacactt ttcctgattg gcccttttgg taacgagcaa
     2761 tcaaattatc tctaccatct ctgtaagaaa caatctctcc tgttatgtca tgttttgcca
     2821 aaagcttatt caaataggct gctacttcac cttcgtttcc attcactgat ttaattcgga
     2881 tgatctcttg taaaatcgcg attttttctt cttttttcat ctaatcctct cccttgccat
     2941 ttctttttat tgtatttgag tgtgctcgaa ttttcaaata ggagcaacca aagtaaaaat
     3001 gaagaaagag agccacttta tgaaaaatat gctgctactt ccctcctatt ttatttatac
     3061 gagaggactt gctcatagat tcctattcta ctgttctatc cttaaaagct cttatatgat
     3121 gctagttatt gttagctttc ctttttcaag gatgatcttt tcttgtacca ttctttgtaa
     3181 acatcatata cagaagctag ttgcaaaaaa actctctacc tgctgatatt tcagcaagta
     3241 gagagttcga ttacttaact aagtgatcat actcgactat ctttcaatag tcgatcatgt
     3301 atcttcatta gaaaagaatt atttgttttt taagttgtag aaagatttca aacctttgta
     3361 ttctgcaact tcaccaagtt ggtcttcgat acgtagtaat tggttgtatt tagcaatacg
     3421 gtcagtacgt gatagagaac cagttttgat ttggccagcg tttgttgcaa cagcgatatc
     3481 agagattgtt gaatcttctg tttcaccaga acggtgagat acaactgctg tgtagccagc
     3541 ttctttagcc atttcgatag cttcgaaagt ttctgttaat gtaccgattt ggttcacttt
     3601 gataaggatt gagttagcaa ttcctttttc gataccttca gataattttt gagtgtttgt
     3661 tacgaacaag tcgtcaccaa ctaattgaac tttgtcgcct aatacgtcag ttaatttctt
     3721 gaatccgtcc cagtcgtttt cgtctaatcc atcttcgatt gagatgattg gatatttaga
     3781 aactaattct tcgtagaatt tgatcatttc gtcagttgtt ttttcgcctt cgcctgagtc
     3841 agctagtacg taaacacctt tttctttgtc gtagaattct gaagaagcag catccatagc
     3901 aagaacaacg tctttaccag gtacatagcc agctttttcg attgcttcga tgattacttc
     3961 aaaaccttct tcgtttgaac caaggtttgg agcaaatcca ccttcgtcac caacagaagt
     4021 tgctaatccg cgagctttca agattgaagc taatgcgtgg aatacttcag cacccatacg
     4081 tagagcttct ttgaatgttg gagcgccaac aggcatgatc atgaattctt ggaagtcgat
     4141 tgagttatca gcatgtgatc cgccgttgat gatgttcatc attggtgttg gcaatacttt
     4201 tgtgttgaat ccgcctaggt agtggtataa aggtacttct aggtagtcag cagctgcacg
     4261 tgcaacagcg atagaaacac ctaaaatagc gttcgcacct aatttacctt tgttaggagt
     4321 tccgtctaaa gcgatcatag ctttgtcgat agccatttgg tcacgaacat cgtagccaat
     4381 gattgcttca gcaatgatgt tgtttacgtt gtcgacagct ttagttacac ctttaccgcc
     4441 ataacgagct ttgtctccgt cacgtaattc aactgcttcg tattcaccag ttgaagcacc
     4501 tgaaggaacc attccgcggc caaaagctcc gctttctgtg tatacttcta cttcgattgt
     4561 tgggttacca cgtgagtcta agatctcgcg agcgtaaaca tcagtaataa ttgacatgtt
     4621 ttgtctctcc tttgagtttg ttttttccta agggatttcc ctcatatacg attttagtta
     4681 attttgctca ttagtgcaaa catttcttgc atttttcaca aattttcaac aattatttta
     4741 cagcgtctaa caatgacaag aatgaatctg cttgcaagct tgcgccaccg actaaagcac
     4801 cgtcaacatt ttcttttgcc atgtattcag caatattttc tggttttaca gaaccgccgt
     4861 attggatacg aactgcttct gatacttctt ttccataaag tttttcaact gtttgacgta
     4921 caactccaca aatttcgtca gcgatttgtg cgtcagctga tttaccagta ccgattgccc
     4981 agattggttc ataagcaata accatgtttg acacttgttc agctgaaaga tcagctaaac
     5041 cagctgtaat ttgtccttcg atccattcag cagttttgcc tgcttcatag gtttctaaag
     5101 attcgccgca gcataggatt ggtgtcatac catttgcaaa gatagctttt gcttttttat
     5161 tgatgtcttc gtctgtttca tggaaatatt cacgacgttc tgaatgtccg atgatcacat
     5221 aatgaacacc tagatcagca agagctgctg gtgaagtttc accagtgaac gcacctgagt
     5281 tttcccagta gcagttttgt gctgagattt ttagttctgt accttcagct gatgtcatta
     5341 attcttgtaa gaataatgca ggagatccga tgactgaatc aactttgtca tttgaaggga
     5401 ttttgttttt tactgcttca gcaaattctt ttgcttctga tgcagttttg ttcattttcc
     5461 agttacctgc gataataggt ttacgcattg aggaacacac tccttaattt attgaaaaat
     5521 ggctagggag tcatgaaaac tcccttcacc ttttgatcga ttactcgtca gaattgagca
     5581 aacttggtcg tttatttatc gttgattgct gctagtcctg gtaattcttt accttcaagc
     5641 aattccaagc ttgcgccacc acctgttgag atgtgtgtga atttgtcagc gaatcctaat
     5701 tgttctgctg ctgcagctga gtctccgcca ccgatgattg ttgttgcgcc ttctaagtta
     5761 gcgattgctt cacaaacacc gattgtacct ttagcaaagt tactcatttc aaatacaccc
     5821 ataggtccgt tccaaacaac tgtttttgca ccttgtaatg tatcagcaaa taattttact
     5881 gatgctgggc cgatgtctaa agccatcaaa ccatcaggaa tgtctccttc gattacttgt
     5941 gtttcaacat catttgaaaa ttctggtgca cagacattgt cgattggcaa gacaagtttg
     6001 tcgcctgctt tttcgattaa ttcttttgct agttctactt tatcagcttc tactagagag
     6061 ttaccgatct tgattccttt tgcttcgtag aatgtgtaag tcattccgcc accgattaag
     6121 attttatctg ctttaggaat caagttttcg attacgccga ttttatcaga aacttttgcg
     6181 ccaccaagga ttgcaatcat tgggcgtttt ggttcttcta ctgcttcacc gatgaacttg
     6241 atttcttttt ccatcaagaa tccagcaact gttgggatac cagttgaagc gatacctacg
     6301 ttagaagcat gtgcacggtg agctgtaccg aaagcatcgt taacaaatac atcgcctaat
     6361 gaagcccagt atttacctag ttctgtatca tttttgcttt cttttttacc gtcaatatct
     6421 tcaaaacgtg tattttcgaa tacgacaacg tcgccgtcat tcatgttgcg gattgcttct
     6481 tctaattgtt ctccgcgagt ttcaggtacg aatgttactt ctttacctaa taattcgcct
     6541 agacgttttg caactggagc taaagatttt ccttctttat cttcttctgt ttttacacgt
     6601 ccaaggtgag agaaaaggat tgcttttccg ccttgttcta gaacgtagtt gattgttggc
     6661 aatgctgctt tgatacgagt gtcgtcagtg atcacgccgt ctttcaaagg aacgttgaag
     6721 tcaacacgga caagaacttt tttgtctttt aaatcgatat ctttcactgt tttcttagcc
     6781 attttatttc ctcctgaata aacttattat caaaaaaagc ggaagaagcg cgattgcttc
     6841 cccgctttta aatgtacatg tctataattt acacttgtac gtttgtctat cttataagtt
     6901 agcgaagtat tctaaagtac gtactaattg tgcagtgtat gacatttcgt tgtcgtacca
     6961 agcaacagtt ttaactaatt gtttgtcgcc aactgtcatt actttagttt gtgtagcatc
     7021 aaataatgaa ccgtaagtca taccaacgat atctgaggaa acgatttcgt ctgtgttgta
     7081 tccgtaagat tcgtttgaag cttctttcat tgctgcattg atttcgtcaa cagttacttc
     7141 tttttcaaga actgttacta attctgttaa tgaacctgtt ggtacaggaa cacgttgagc
     7201 agctccgtct aatttaccgt tcaattcggg aattactaaa ccgatagctt tagcagcacc
     7261 tgttgagtta ggaacgatgt ttgcagcagc agcgcgtgca cggcggaagt cacctttagg
     7321 atgaggtccg tctagagtca tttggtcacc tgtgtaagcg tggatagttg tcattaatcc
     7381 ttcaacaaca ccaaatttgt cgttcaatgt tttagccata ggagctaaac agttagtagt
     7441 acatgaagca cctgagataa ctgtttcttt accagttaat gtttcgtggt ttgtgttata
     7501 aacgattgtt ggaacatcgt ttccgccagg agcagagata acaacgcgtt tagcaccagc
     7561 tgttaaatgt ttttcagctg ctgatttaga agtgaagaaa ccagtacatt ctagaacgat
     7621 atctacgcct agttcgcccc atggtaattc ttctgggttg cggttagcta atactttaac
     7681 ttcttttccg tttacgttga atgaaccttc atgaacttca actgttccgt tgaaacgtcc
     7741 ttgagttgtg tcgtatttta acaagtgtgc caacatttta gcatctgtca agtcgttgat
     7801 tgctactact tcgattccat ctacatcttg gatacgacgg aatgctagac gtccaatacg
     7861 tccaaaacca ttaataccta ctttaactgt catttaagat ttcctcctta tgaaaatcaa
     7921 aaaaatattt attttaaagg gttacccctt ttaaaatctc atttgcagca gcttcatcag
     7981 tgatgagcca cgtttgtttt ggtgcatttt tcatataagc tcgaattgct ttagcttttg
     8041 attttccgcc cgcgattgcc atgatgatcg ggactttttc caaatcttgc aattctatgc
     8101 cgattctagg gaccttataa acgacttcac ctttttcatt gaaaaagtag ccaaaagatt
     8161 ccgcaacagc atttgcttgt ttcagcatga ctaattcttt ttcagtcatc ttacgacgtg
     8221 ctgccatgtg taatgcacgc ccaatactat gaataacaca attcgcttca ctaatcaagt
     8281 ttaagacttc ttggatagat ggctcattga gtaaagaatt gtaagttgcc agacttaatt
     8341 gttccggaac ataaagtgcg cggtggttac cgtttgcttt agcagccatt cttgcactga
     8401 cagaatttgc ctgtacagtt atcgcttcac caatcccgcc tcttgcaggg acaaacaggt
     8461 tatgccgttt cttattttcc agattagaca attgttcggc taccacagcc atagtagttc
     8521 ctcccatcac agcgatgata ttctcgcctt ctggaagtag tcggtctaag gcttcgctca
     8581 gcgcttcgcc gaatgcatca gccactttgg tctgctcttc gctgtttcct gaaacaacga
     8641 tacagcgttg gttaccaaaa tattctgcca actgttgttc ggtttgatgc gtacctaaaa
     8701 gctgatccat gaagttttca aggctttgat aaacttcttc gcccttagtt gtcagcgtca
     8761 taccgctttt tgaggtgtcg atcaaattca gatttttcaa aaggtctgtt tctgttcgta
     8821 agactcgttc tgtgatcccc atactttccg ataaacttcg acgcccaatc ggctgcatcc
     8881 aatagatatt tcgtaaaatt ttatagcgtt cttgcaacac ttcgataata tctggtgcaa
     8941 cagattcaat catttttatt tcatccagca tagcgatctc cttagttgga cactttacgt
     9001 ccaatgtaga cttaaaacga cccatatacg ataaaaaaag aaattaacta ttcgaatttc
     9061 acatcaataa agggaaatct caacctcacg actgtaagtc taacagtttt gctctcgttt
     9121 ttcaactaaa aagactagaa aaagtgaaat actttttcta gtcttttgac tgattagtta
     9181 tcataacgtt ttctttttga tgaactcggg attcctaata aatcacgata ttttgctact
     9241 gttcgtcttg agatcgctat ctcatctttt ttcagcaatt caaccaattt ctggtccgac
     9301 aacggcttgt ttttgtcttc ttgatcgact aattcctgca gctttttctt cgctgtatct
     9361 gctgaaaggt cttctgtctg ttctgtacta ttcgtaggaa ttcgtgtagt gaaaaatttt
     9421 tttaattcaa atacaccgaa atctgtttcc aaatatttcc cgttgactgc acgactgacc
     9481 gtggattcat gcacatctat ctcagttgca acttccttta acgtaagagg cttgattgga
     9541 cgttccttgt cgataaagaa agctttttgc cgggaaacaa tgacttgagc aacccgcaaa
     9601 attgtatccc cacgttggag gatcgttttc ttcaaccatt cgaattcctg tttccgttct
     9661 tttaaataat tttcagtttc tttatctgct tgttgtgaca tttgtttgaa gtaactctct
     9721 tgaaagcgta tatttggctg attttttcgg tttgagataa cttgtacatt tttatcgtcg
     9781 tccactaata cccggacatc aggaataatg tacaattcgc tgctacggtc gaaaatccgg
     9841 ccagggcttg gactcaacgt ttgtaaatag tcgaatatct gctgaacagc atgtagatca
     9901 acagaaaaac gttgtgcgat ttctttccat tttcgctcca ccagttcctc aaaacattct
     9961 tccaacacga tataagctaa ttccggcgca taatcatctc gttctgtttg aagcatgaga
    10021 cattcttgca aactacgtgc acctactcca gctggttcta attgctgaat cagagtcaac
    10081 gcatcgagca tttggatagg cgtagctcca atctcttttc cggcttcttc taaactaatc
    10141 gtcaaaaatc cgttcaaatc gatgtattct acaagataaa gaacgatttt cctcaaaaaa
    10201 gtatctcggt aattcaaatg gacttgttcg atcaatgaat caaataaaga cccttttgta
    10261 tcaggaatct gatttaggta atttgtctct tctccttcat aagaagatga agaagctttt
    10321 atgtaatctg gctgccattc cggctcaaca acttccacca atggattttc cattgcttga
    10381 ttctcaacga atgccaacag ctcctcactg ttatattgta aaacttggat ggactgttgc
    10441 aactgttgcg tcatggctag tttctgtgtc tgctgctgtt tttgtgaaaa attttgctca
    10501 aatttcattt ttttgtccaa tccccttgta attttttatc tgtttagtta caattatccc
    10561 agtgcttgcg tccttagtgt agtggatatc acgtaagatt ccggttcttg agacgggggt
    10621 tcgattccct caggacgcgt tctactgcta ttttagcata atttacgaat agttgcttct
    10681 ttatttttaa gtgaaaactg tccgccaaag agaattggtg gacagttttt tgttgtatct
    10741 gtatagat
//
LOCUS       DARPZJ010000076        10156 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.079, whole genome shotgun sequence.
ACCESSION   DARPZJ010000076 DARPZJ010000000
VERSION     DARPZJ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.079"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(560..1600)
                     /locus_tag="SLE23_002455"
     CDS             complement(560..1600)
                     /locus_tag="SLE23_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8469325.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="SLE23_002456"
     CDS             complement(1949..2275)
                     /locus_tag="SLE23_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469326.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3065)
                     /locus_tag="SLE23_002457"
     CDS             complement(2262..3065)
                     /locus_tag="SLE23_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8469327.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3418..3708)
                     /locus_tag="SLE23_002458"
     CDS             complement(3418..3708)
                     /locus_tag="SLE23_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEI8469328.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3844..4023)
                     /locus_tag="SLE23_002459"
     CDS             complement(3844..4023)
                     /locus_tag="SLE23_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469329.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4020..4370)
                     /locus_tag="SLE23_002460"
     CDS             complement(4020..4370)
                     /locus_tag="SLE23_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469330.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4363..5688)
                     /locus_tag="SLE23_002461"
     CDS             complement(4363..5688)
                     /locus_tag="SLE23_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEI8469331.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6138..6752
                     /locus_tag="SLE23_002462"
     CDS             6138..6752
                     /locus_tag="SLE23_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8469332.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6917..7921)
                     /locus_tag="SLE23_002463"
     CDS             complement(6917..7921)
                     /locus_tag="SLE23_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469333.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(8380..8637)
                     /locus_tag="SLE23_002464"
     CDS             complement(8380..8637)
                     /locus_tag="SLE23_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEI8469334.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8630..8899)
                     /locus_tag="SLE23_002465"
     CDS             complement(8630..8899)
                     /locus_tag="SLE23_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8469335.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9030..9209)
                     /locus_tag="SLE23_002466"
     CDS             complement(9030..9209)
                     /locus_tag="SLE23_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469336.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(9590..>10156)
                     /locus_tag="SLE23_002467"
     CDS             complement(9590..>10156)
                     /locus_tag="SLE23_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469337.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3101 a         1855 c         1458 g         3742 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgttac taataattcc cttcttatag tgcattttct tagaaaaaaa
     3361 caatattacg atatcatgat attaagatat cgtaatatta tacaattgtg attgatatta
     3421 tatatgtttt tttatttttt tatcatgttt aatcttgaag gaatcatatt ctttttctaa
     3481 agacaggagc ttttcataaa catcagacat gtttaaacta gaggccaggc ttaaatcata
     3541 aacgaatgaa gcaggtaatg attttattct acgttgtcgg gttatccagc ttgcaaccgt
     3601 tccttgtggg taggcatata actcacaaaa ttgttctaca gtgattccta aattcttgat
     3661 aatgtaaaca ttgatcgggt gcgagtaaac aaatgtattg atagacatgg tgcgtaagcc
     3721 tactttcttt tattattgcg tttgcaataa tagtttaaca cacgcattat tctagtatct
     3781 actcctattt gtaaaaacaa aaaaggattc atagagataa ctctatagaa tccgtaaaat
     3841 accttatata tataacggga agatataaaa cctaaaatta tgataacctg ctgcagcttc
     3901 tacatagaaa gagaagcgct caacaccaac ctcatttatc aaacgttggc cataacccca
     3961 aatctcttct gatagctgat caaaggttat atactttagc tcatattgct ggataatgtt
     4021 cattctaatc gactccattt attatcctgg taaaattcga tatgacgtat ttcgtcgtag
     4081 tgaattttgt cttttccaac gtagatcccc agctcatcac tacctaagat cttgccaatg
     4141 atatcttctg gatagtatcc ttcagcgttt cgttcttctt tttgaataga tactgatcta
     4201 ttttttatga ctgcagcgtt caatacttcc gcaatctctt cagtcgtcat ttgttctttt
     4261 gctaaatttt gactggttcg ttgttcattg tcggcatcaa tttcttcagt atgatcagat
     4321 aaataaaacc ctgcccactt taaacgtcca cgatcattgt aatcaatcat ttttaattcc
     4381 cccatttccg cccgcatgac caccaacaag tgtgcttcta gtaatgcttc tagcgccttc
     4441 taacattgaa gaagcatgta caatcgacgt aaaaccatat ttttgccgaa tcttgtcaat
     4501 aattttatct aaattttctt cgtcaatttg cttttgtgga tcactaaata aatccagctg
     4561 aagcgaatcg gtgtacacaa gcttgctata ggttattcca acatgcctta cttcttgtcc
     4621 ttcataatac ttatcaaaca agaaaagaca ataattctgc aattcctttg tattatctgt
     4681 gatagggatc ttcatctggt gtgaaaaccc tggtctcgtt tctaagatcg acgtgccaat
     4741 gtgtaaatgg acacaacctg ttttacagtt atgctgccta atgcgtatcg ctacttgttc
     4801 cgccatttct tttaccacca gctcgatttc atttcttcta gtataatctc gtggtaacac
     4861 ttgtgaattt ccatatgatt tttcctttgt cggttctggt gggattgcta tatctgttcg
     4921 atcgatccca ttagcatgga agtacagctg taagccaatc acacctagtc tattcttaat
     4981 cgtataagga ttccagttag caagatctct aatgctcata atccccatct gattgagtct
     5041 ttttttcatt cgagagccaa ttccccaaaa gtccgtcatt tcaggaatat tccatacttt
     5101 ttcaggaacg ttttcgtacg tccattccgc aacaaatcct tcattatgct ttgcttcgtt
     5161 gtctaaggct agtttagcca aaaggggatt atctccgaca cctactgtag caatcaatcc
     5221 tagctcttct ttaatattct cctggatcat ttgagccagc ttctttctcc gttgacttcg
     5281 tgttccttca gtcgtaaaaa gattcagtga tcgggtcact tttaagattg attcatcgat
     5341 cgagtaaatc agtagatctt catcagccac atatcttctg aaaatattat ttacctgcat
     5401 atttcgcttg atatataggt tcatacgtgg tggaacaacg tgtagtgttt taggaaatgg
     5461 ttgtggtaag tcacgtggtc tactcacatt tgtaatacca taccgctttt ttgcttcagg
     5521 agaagaagct aatatcaatc ctgaaccagt attatcagct cgactcataa caacaagttc
     5581 tgttgttaat ggatctaaat ttctttctat acattcgaca cttgcgtaaa agcttttcat
     5641 atcgattaaa aagtaatcat ttactggctc ttttgaataa tccatcataa ataacactcc
     5701 attctttcac attatacaaa catatgttcg atattgtaaa gaagaaatag ctaaatacat
     5761 aaaaaaagaa gcataggtat gctatcaccc tgcttcttct tttgatttgt atgatcaatt
     5821 tattctatca ctttactaat taatttgaaa atctaataaa aactctcact ctaaaagagt
     5881 gagagactgc aaattagagt acggactttt ttggagttcc gttctttaat attaacaaat
     5941 gaataaaatc cttacaacat ttgagaataa gttatcagta gacacttaca aaaaattctc
     6001 atactatttc ctccatcatt agtttttgtc tatataaggt ttaccctaaa tagacactgg
     6061 tataacattg aaaaatatgg cttcctcgtg tatgattagg gtgtatttta aatagttgca
     6121 gaaagtaggt aaaagttttg agagttgcat acatacgtgt ctcatcgatc gatcaaaatg
     6181 aacaacgcca gattgaagaa atgaaaaaat tcggtgcaga gagaattttc atcgagaaac
     6241 aatctggcgc aacgattact catcgacctg ttttccaaga agcattagat tacgtccgag
     6301 atcaagatat ttttattgtg gaagctattg atcgacttgg aagaaattat gacgagatca
     6361 tcgcttcagt caattacttg aagaagaaaa atgtgaagct gatcattact agtttaccga
     6421 tcatggctga agcaattggc aatcctctcc tggataaatt cattaaggat ctgatcatcc
     6481 aaattttggc catgatcgct gaacaagaac ggactgaatc gaaacgtcgc caggcacaag
     6541 gaattaagat cgcaaaagca aacggcgtct acaaagggcg gcccaaatta tacagtgcag
     6601 acgcaaaaga tccccaacgt cgccttgttt acaaaagcat cgttgaagat cttaaaaatg
     6661 gtgttgcgat tgctaagatt gctaaagact acaatgttac gagacaaacc gtgtatagaa
     6721 taaaaaaaga cagcatggtc aatgacaaat agttgatcat gctgctttta ttatcttctc
     6781 atctttaatt tcctacatat aattactatc tataaaatta agtcttactc agaacagata
     6841 aagcataaaa ttccaacaaa ccatttttta cttaactaaa taaagagtct gttaatataa
     6901 tcttcactta tttacgttaa tcccctactg tatttgttgg ttccttatct atattttcta
     6961 caaaatcctt attatcttgt gatttagctt cgtataattc tttgtatgtc gacacattgg
     7021 ttatactaat tcctatagct agttcttgag actctacttt tctctctagc tcctttgaca
     7081 aagtgatttg agatttattt ggttccgttg gagtcaattc tatagattct tcataaaaat
     7141 ctctatacat aaagctatca ttaattttat aaaaaaaatt aaatgttttt agcactgcca
     7201 tataacattc aaaacattct tctatagttg gtttacttcc ttgaggagaa tgaaccaatt
     7261 tattacgttt ttctatgaaa tttttaattt cctttcttat ttctttcgga aactcaatat
     7321 taaagtaccc tttaaacatg ctccctaata atttgtctac agggggagat tgtaaattct
     7381 caaatattag agttaaatca ggtttctctt gttgataaaa ttcctttacc cctatttcac
     7441 aggctgtaat tatcgaaata aacctatctc tagtatttga tatattttta cttcttttaa
     7501 ggagtataag agaaaagggg atactttcgt gtccatgcat gtaattaact aattgttgag
     7561 cttcagaagt tatatctcta attatatagt taacggaatt aggaagtgtc tttaactcta
     7621 atgaaatttc tatccaatta ctatcttcta atctgtatat gctcgaagta taatttgatt
     7681 cgtcagcaag catcgctaca tcccaaacac tgatcataaa atcttttaaa cgttcaatca
     7741 tttcagcaat attgctaaaa tcagctaatt tttctttaga ataaaaaaaa acatttatat
     7801 cagaatcaat aaattctatt ttttttatta ctatatcgtc atcattatct tgaccattta
     7861 tgtttattgt tccctgagtg gggagtactt ctttcaaatt caagttaaat ttatattcca
     7921 ttacttctcc tccaatatat aaaaattact taactgtatc caaatttaat atgtaaataa
     7981 atcattaatt tttagctaaa ttctatgaga agtttatttt tgttgttttt gctaattaac
     8041 taaaactagt acaaaaaatt taaaatagat tattaaacct attgcttatt ctattcagtc
     8101 atatatataa gcgtcatcct ttagtaacta acatcccaca ctacaatagt attataacat
     8161 atctattcaa cttcaaattg ttgaaattta agccatttat atttactttt cctcaacttt
     8221 agaaatgatt ttactaacct tatatccgta atacgcgtaa caaacacatt cattaataac
     8281 aatcaacact aagctatatt agctttttaa atgactaggg taaataaaat aaggatcaaa
     8341 aacttttaag tttctgaccc tttccttact tccgattggt taatagtgat cttttgcaga
     8401 ataaataaat atcgtttcat tttcaactct atatatcagt ctatgttcat ctgtaattct
     8461 tctggaccat tttccagata aatcatgctt taatggctca ggttttccta atccagcaaa
     8521 gggggaacga tcgatatctt ttattaactt gttaatcttt tttatattgc ttttgtttcc
     8581 ttgctcatgc caataaagat aatcatccca agcatcatca gaccaagcct taatcatcag
     8641 attcaacctc gattaagtca tgtgttttaa atgcaccttt ggagaattgt tcatctcctc
     8701 gacgaatttt ttccatgacg taattattag aaagtgttct caacgtttct tgcatagaat
     8761 cataatctct ttttgataat acaacaactg tatcttctac atctttactt gttacaataa
     8821 gtgtttcagc atcctcatta acttgtttca tataactacg taaattttgg cggaaatttg
     8881 aataagctac tgcttccatt cctttcaccc cttatttatt tctataaaac aattgtacat
     8941 tatattgtac aattaagcaa atgattaata ttctaacttc ttataattaa aagtgctatc
     9001 acttttagtt tttaggataa aaagtgacgt cactttttga gtgctggtac ctcaaatcct
     9061 gctttttctt gggcaatcaa taaatctaac gcaatacaca taatcctgga ttcacttttg
     9121 ccgtacttct gctttagttg ctgcaattct ttttgtctct tttcatccaa cgtaacgggt
     9181 aaccgtttat ttcctattgc aattggcatt agtactctct cctttcatcg aaataaccct
     9241 atgaaaaata tggctgcaat catcttgaat agtagactca caagggctaa tacaaagcgc
     9301 caaaagatca aacaaaatac cagtattgcc aaaaatacta cgaagtttaa atgcacagct
     9361 gcagcatggc gcataagtat ttcgccaaca aataggacta acaatagagg aatgatttta
     9421 ttcatatgga tctccttctt tctcttaggt tatcgggtgt tgcccgctta tttcgcacca
     9481 cctaagcggc gggggcggtt ggagcgattg gtgcgaaata agaaccattc ccttagttac
     9541 taggtttttt gtccttattt cacacattct cacttttcgg tataaatgat tattgccttt
     9601 ttttcctttc aaatcgttga tatggcattc gtttacggtc aagttcattt tggatttctt
     9661 ctgtatcgtc gtaagtatag gtgtctaaaa aatcagttaa agtcgtgtac cagtcgtcgc
     9721 ctgggttatc tacttcttct acatattccc tcaaaaatgc ttcgggtaca gcgagttcat
     9781 aatccattcc cattaacacg atagattccg ttccacacgt caaaaatcta gtaaatacaa
     9841 ggtaataatc gtctatcgtc gcatctttgc tgtttagctc ttccatttct tcttccatta
     9901 attccatgct ctcaaaaatt gaataatatt ctgattctga gtaatagtgt ttcctgcaaa
     9961 tcgtgtagct gacaaagttt tcgaccagct cactcctttc taggtaaaca ttcatgatgt
    10021 atttttctgt ttctagtcgt agaagctccg ttcctttttt taccgtttca ggacgacgtt
    10081 tatacacgtc taaacgatta tggctgactg tgaccttcgt ttgactcgtt tcactttcca
    10141 aatacaattg ttcttc
//
LOCUS       DARPZJ010000077         9965 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.080, whole genome shotgun sequence.
ACCESSION   DARPZJ010000077 DARPZJ010000000
VERSION     DARPZJ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.080"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            8..81
                     /locus_tag="SLE23_002468"
     tRNA            8..81
                     /locus_tag="SLE23_002468"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="SLE23_002469"
     tRNA            101..173
                     /locus_tag="SLE23_002469"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="SLE23_002470"
     tRNA            201..274
                     /locus_tag="SLE23_002470"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="SLE23_002471"
     tRNA            288..361
                     /locus_tag="SLE23_002471"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="SLE23_002472"
     tRNA            385..474
                     /locus_tag="SLE23_002472"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="SLE23_002473"
     tRNA            487..560
                     /locus_tag="SLE23_002473"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="SLE23_002474"
     tRNA            579..654
                     /locus_tag="SLE23_002474"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="SLE23_002475"
     tRNA            656..726
                     /locus_tag="SLE23_002475"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="SLE23_002476"
     tRNA            740..813
                     /locus_tag="SLE23_002476"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="SLE23_002477"
     tRNA            838..925
                     /locus_tag="SLE23_002477"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="SLE23_002478"
     tRNA            947..1018
                     /locus_tag="SLE23_002478"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="SLE23_002479"
     tRNA            1041..1130
                     /locus_tag="SLE23_002479"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="SLE23_002480"
     tRNA            1143..1216
                     /locus_tag="SLE23_002480"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="SLE23_002481"
     tRNA            1235..1307
                     /locus_tag="SLE23_002481"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="SLE23_002482"
     tRNA            1311..1383
                     /locus_tag="SLE23_002482"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="SLE23_002483"
     tRNA            1388..1458
                     /locus_tag="SLE23_002483"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="SLE23_002484"
     tRNA            1471..1544
                     /locus_tag="SLE23_002484"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="SLE23_002485"
     tRNA            1556..1627
                     /locus_tag="SLE23_002485"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /locus_tag="SLE23_002486"
     CDS             1893..3086
                     /locus_tag="SLE23_002486"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEI8469338.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="SLE23_002487"
     CDS             3216..4688
                     /locus_tag="SLE23_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8469339.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="SLE23_002488"
     CDS             4771..5559
                     /locus_tag="SLE23_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEI8469340.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="SLE23_002489"
     CDS             complement(5626..6294)
                     /locus_tag="SLE23_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEI8469341.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="SLE23_002490"
     CDS             6409..8121
                     /locus_tag="SLE23_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469342.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9896
                     /locus_tag="SLE23_002491"
     CDS             8124..9896
                     /locus_tag="SLE23_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469343.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2900 a         1781 c         2279 g         3005 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa agttaaatta
     9901 aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt ttttataagg
     9961 ggcag
//
LOCUS       DARPZJ010000078         9316 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.081, whole genome shotgun sequence.
ACCESSION   DARPZJ010000078 DARPZJ010000000
VERSION     DARPZJ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.081"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..2122
                     /locus_tag="SLE23_002492"
     CDS             <1..2122
                     /locus_tag="SLE23_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469344.1"
                     /translation="KKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQYK
                     DDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKY
                     GTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFD
                     TIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTL
                     SIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLKYW
                     ERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQENN
                     KEFFIGQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTTYI
                     LVPKKYKEYAKMIEKNYLEDIQFRLEDSPPQAPYKNPNLKNLKIKLIFVNNNQKYFSF
                     NTLYGKAKDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQIN
                     PYIKEFNLENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIFVS
                     FTINSKKIALKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFMIF
                     LINLITSIIIYKKNSFKYFKENIL"
     gene            2119..2739
                     /locus_tag="SLE23_002493"
     CDS             2119..2739
                     /locus_tag="SLE23_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469345.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            2853..2990
                     /locus_tag="SLE23_002494"
     CDS             2853..2990
                     /locus_tag="SLE23_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469346.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            3432..3812
                     /locus_tag="SLE23_002495"
     CDS             3432..3812
                     /locus_tag="SLE23_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEI8469347.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            3794..4708
                     /locus_tag="SLE23_002496"
     CDS             3794..4708
                     /locus_tag="SLE23_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEI8469348.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            4948..5637
                     /locus_tag="SLE23_002497"
                     /pseudo
     CDS             4948..5637
                     /locus_tag="SLE23_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5757..5843)
                     /locus_tag="SLE23_002498"
     CDS             complement(5757..5843)
                     /locus_tag="SLE23_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEI8469349.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            6488..7225
                     /locus_tag="SLE23_002499"
     CDS             6488..7225
                     /locus_tag="SLE23_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEI8469350.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            7253..7792
                     /locus_tag="SLE23_002500"
     CDS             7253..7792
                     /locus_tag="SLE23_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEI8469351.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            7808..7978
                     /locus_tag="SLE23_002501"
     CDS             7808..7978
                     /locus_tag="SLE23_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469352.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(8290..8751)
                     /locus_tag="SLE23_002502"
     CDS             complement(8290..8751)
                     /locus_tag="SLE23_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8469353.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPD
                     IETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNIFVTILGLFELIQMNFFS
                     FTHGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
     gene            8884..9258
                     /locus_tag="SLE23_002503"
     CDS             8884..9258
                     /locus_tag="SLE23_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEI8469354.1"
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
BASE COUNT         3596 a         1413 c         1455 g         2852 t
ORIGIN      
        1 aaaaaaaata aacgctgttt tatcactttt tgtctgcatt acaatactat ttttttctac
       61 taatgttata aatggtataa agacttctga agcgctatat aaaaataccg ctgaaattca
      121 tatgcaatat aaagatgata tggactttaa cagttatata aacgctttgt atgaaatatc
      181 tacacaagaa aatattaata tttctcaata tagttttact gctgttaacc aactaactat
      241 tcttgctaca aaccctaacg ctaacaaaca ctggaaattt tctaaaaaaa atatattagc
      301 aagaaacgat tctaaagtcc attatactaa taacaaaaat tctaagtacc aattaaaact
      361 tccaaataat tttttaaata taaatattta tcctttttct catgtggaaa atattggatt
      421 aagtgaaata ttatatgtac aaggaaactc aaacaaatta attcctgtac tgaaaaaata
      481 tggaacacct actatttcca atatcaatca atcagatact tttcaaatta atactaatat
      541 tgttcttgtt atctgctatc ttagtatatt tattgtaatt actacaatta tatttgcttt
      601 ttcaaaaatg aaagaaatca ctctaaaaaa aatgttaggc tataactctt ttgatactat
      661 aaaagattct attaaagagt taaacctctt attttgttct ttgattataa ctttcatttt
      721 atctattttt ttgagcatat attacagtaa cgaaaatttt ttcctatcat ttcttctatg
      781 tagtattttt cattttataa ttagtttttt atttatcata gttactctaa gtatctatca
      841 tttatctagt ataaaaaatt atctaaaaaa ttcacgacca cttaagttaa atctttgtat
      901 attaaatatc tgtctattct taagcatgat ccttctgtta atagcttcta caaaagtaat
      961 aaatacccat aatgaagccg aaaataattc tcttaaatat tgggaaagaa ctactaattt
     1021 atacaaaaca aatattacta atcaattaaa tagaaacaac accgtagaag aaaataacta
     1081 cttgaaaaaa gctagtaaat ttgtttataa aatacagaag aattataaaa cttttattat
     1141 cgcgccatac aattacgcaa ctatccaaga gaataataaa gaatttttta ttggacaaaa
     1201 agtttatcca aattttgaag actatgttag tcaacctgct ggtgcaggaa tatgtgttga
     1261 tttaaactat ctaaaatatt acaatcctat ttcttttgaa gaatctactg acttaaattt
     1321 aataaactct gatccactaa ctacttacat tctagtacct aaaaaatata aagaatatgc
     1381 aaaaatgatt gaaaaaaatt atttagaaga catacagttt agacttgagg actctcctcc
     1441 tcaagctcct tataaaaatc ctaatttgaa aaatttaaaa ataaaactaa tatttgttaa
     1501 taataaccaa aagtatttta gttttaatac cttatatgga aaggcaaaag ataactatac
     1561 aataactgat cccatagtta gagttattaa tccagaaata acagaatcat tattttgggg
     1621 aaatatattg actagtgatg gtggattatt ttttgatcag aaacatactt caaaccaaaa
     1681 cttttttaat caaattaatc cgtatataaa agaatttaac ctagaaaata tcataaattt
     1741 ttcttattct gtttttcaag aaactggtga attattatct caaaaaaaag taaataaatt
     1801 aaatgcatat ctacaatatc ttttaatatt aggattattt ataataatta attttcaaat
     1861 gatttttgtt agttttacta taaattcaaa aaaaatagct ttaaaaaaaa tatttggata
     1921 ttcaccaata agtcaagttt tagatttatg tttactccct tttacaatag agttatttgc
     1981 tactatgtgt tttcaattga tattttcaaa aaacacttac ttgtatttta taatttttat
     2041 gatcttttta ataaatctaa ttacttctat tattatttat aaaaaaaata gttttaaata
     2101 ttttaaggag aatattttat gatattatca gttgagaatt tcaccctgtc aattaataaa
     2161 aaaaagatca aacaaaattg gaacttttca atatcagaaa aagattttat tatagtaaca
     2221 ggaaaaagtg gtagtggaaa aactactctg ttaaataatt taagcctaat agataaacaa
     2281 tataccggta acttattcta ttttgaaaag aaagtttcta aacatgatat acaacgtcta
     2341 cgaagaaatc atattagcta tttatttcaa aactatgctc ttcttgaaaa tcaaacagta
     2401 caatacaatt tcgaattagc aaaaaagttt aacagtaata tttccaatga tcatatttat
     2461 aatttattaa cagatttttc tttgccaaaa gatatcttaa aagaaaaaat ctttctctta
     2521 agcggtggag aacaacaaag aatagcatta attagaaata tgttaaaacc atttgatata
     2581 ttatttgcag atgaacctac aggaaattta gataaagaaa actcaacttt tataatgaac
     2641 tttctgaaaa atttaacaga aaaagaaaaa aaagccgttg tactagtaac acatgactta
     2701 aatgttctaa actatggaac taatattata gaattataat ttttacccgt gatgctagct
     2761 gatttaaaac tagcaccacg ggtatttatt ttatattcca tctctcctat cccaaaattt
     2821 aaataatcac ttaataaaaa ggaggcaccc aagtgatttt attgaaaaaa gagtatgaaa
     2881 aattttatga tagacttatt tattctttgc aattgccaaa aaaattaaac cgtcaattac
     2941 aaaagactta tgaaactaaa tcaactgaag aatgggagag ttattgctag atttttggta
     3001 gaagtaacaa aaagtggaca tattatcata atgactcgcc gaaagtctga taaaaaattg
     3061 gctaaaaata ttgctgaatg tttaataaaa ctatcagttt tagctaaata gttagtagtt
     3121 tacacaaaaa agcatttatg ttttttgttg caaagcaaca atttcatctt cggtgaaata
     3181 agcgaaactt tacaaaaagt ggctagcatt tgctagcttt ttttgtattg tggagcgtgg
     3241 cttttgaggg ggattcaagg gggagcttgc gcccctttga caagcggtta tttgcactaa
     3301 atacgtaggt atttggctag caaatataga gcttgccaaa cccttttagt gagctttact
     3361 cattgtacct ttttaggtac aatggtattg cgaacgatac gtccgtagga cgtactgaaa
     3421 gggtgggact tatgagcgaa caaaatcaaa atttggctag caattcttct aaaaaatata
     3481 cctatcgatc cgagccaaaa caaatcagtt ttcgagtgag cgaatccgaa tttgcaaagc
     3541 tgaagcaatc ggctgaagct ttgcaaatga gtgtgccggc tttcgtgaaa gccaaggcac
     3601 aaaacgcgcg tctggtgaca ccgaaagtgg cgccagacat tgcccaggca atcgcgcgcg
     3661 atttagccaa agctggaggg aatatcaatc aaattgctaa gtggtgcaat acacaccaac
     3721 atgacgttgc ttctggtgac gctcaacgtt tatccgaaaa cctaaaaatc atgcaaaagg
     3781 agctacaaaa gatatggcaa caattaaggt aagccgaacc acttcttgta gtcgtgcaat
     3841 taattacgca gaaccacgag caaccattaa aacaggaata aactgtgacg tcgattatgc
     3901 caaaagtgaa atgaaacaaa ttcgcatgct gtatggaaaa gacgaccgtg tacaggcaca
     3961 cttattgatt caatcttttc gaccaggaga aattaccgct gaaaaagcta atcaactagg
     4021 ggcagagtat gcaaaaaaaa tagcccccga tcaccaaata gctatttaca cacatacaga
     4081 caaagaccat attcataatc acattgtcat taactccgtt aatctggaga ctggaaaaaa
     4141 atttcaagct catggtcaag catttctaaa caaatgttat gacctaaatg acgagatttg
     4201 tcttgcacat aacttaccaa tcactgagcg aggaaagaaa ccagaaaaac gaaccatgtc
     4261 tgaaataaaa ttaaaagaaa aaaatgaacc tgtttggaaa gacgaaattc ggattgcgat
     4321 cgatcaaaca atgaaaaaca aaaaaaccag aacctatgac caattttgta attccctcaa
     4381 aacattgggg attcattgct tcaatcgcgg gaaaaatttc acttacgaat tgatccacaa
     4441 aaagaaaaaa gtacgatcca acagactagg aaaggactac gaaaaggaga cgattttaca
     4501 tgagctggac agacgagaac gaacctataa ccaacagcga accaacgagc tacgaagagc
     4561 tcgagctagc attcgcgaaa ctgcagaaga agtacgaaga gaacaacgaa ctcttacgcc
     4621 tgaacaaccg gaaattagac cggctcgaag aaaccatgaa caacacgttg aaagaggaac
     4681 agaccaccaa caagaattat cgctctaaaa cgttaaaaga catagaaaac gaaataaaga
     4741 aacaacgtgc ttttctcgtt ccttatacgc aagaaaggat acaaactacg attgatttac
     4801 aagttaaaaa actccatcaa gagctattag accagcgaaa taaggaacag aaaaaggtgc
     4861 ttattcaacg atcattggat tttcttgccc ccttatgttg cttagtcctg acactgttcg
     4921 cattttggtt agtatgggga ggctaaaatg gcattttatt taccctatct actcattttt
     4981 gttagtattt caggaagtat ttggctcatc tataaaattt tttaaacaag atattcatta
     5041 aaaggctcta aaattcgatt taagcgattt ttctttcttg gctgtatatt ttccttgata
     5101 atcgtttcaa gcggcttatt cggcgtttta gagggaaata agcgcgtttc tagaagtatt
     5161 ttattaggaa atgtcactca aaagtatgaa tcagcgcgtg ataaaaagaa aaaagagcaa
     5221 gcattagcac aaaaaatgga agagtttacc acttgttatg aggaaatgaa cgatattttt
     5281 gtgaatcaag aaaaacgttt gacggataaa aacatggaaa aactcactcg tctttatcaa
     5341 aacttgccag aaaaacagca aaaagaggtt caagacaact atgagcgaac caaaaaagac
     5401 gtgcaatatg taaaagatac aaagatagaa gaagcctgta gtgatctatt tggagacaca
     5461 aacccttggt ttgccagtga agaagaaaaa aaagaaaaac aacaatctgt cacatatgaa
     5521 cgctatgaaa tcttacttca acaagcaact aacatgcaaa atccgacaaa aaaagaaacc
     5581 gccttaaact atctaaaaag tgtcaaggaa tggttagatc agcaacaaca aaattgaatt
     5641 tgatttaaaa tcatgttaaa ctgaatgtgc aaatgatcaa acattagata cacgaaagcc
     5701 ccagagaggt cggattctct ggggcttttt tcaggttgat gtcgccttta ttgattttac
     5761 ttcttgtttc ggttattcaa ccaataactg aataaagaga cacaaactcc tacaagaagg
     5821 gggcaaatga acagttcaaa cattagatac acctccttcc agtcgcaaga ctgtcggata
     5881 ggcgacaagt tattatatct taaaaaatta aatttgtgtg gtgtttttaa gtatcacttg
     5941 ttttagggtt gttagggctt gccctgaccg cctgtaaggc gcttctcgac tagattaagg
     6001 gaaattaatc aagaattgtc ttagaacggc ttagacaagc tttcagagtc tcacacctcc
     6061 tctttgaaca acggttttag caaaggagcc ggaggcgact gcgcagtata atatgagagc
     6121 atagcgatca caccttttta gcgaccgtag ggagcaagtt ttccagttta gaaaaattcg
     6181 cgaacctttt tggaggaaaa agtaggagtt ttttaggcgg gaaattcaat gtgctcttaa
     6241 gatatactgt tagatatact gttagatata ctgttaataa taactgttag ggattagcaa
     6301 ccttatggga gagtaagtat tgacataggt agtgggggat aaattgtcac actatggggg
     6361 ataaattgtc acactatggg ggataaattg tcacactatg ggggataaat tgtcacacta
     6421 tgggggataa attgtgtttt acatcctctt atgtctatga taacataatt tattgaggtg
     6481 atttttattg agtaacgata tagttcgata taataatgga ttaaattctg tccctttaag
     6541 aaaatttacc cctatagata tggatttatt ttggggaata tgttctaaaa tgaaaagaaa
     6601 aggtacaaaa gaagaaattt ttacatttaa acaaataaaa gaattaattg attacaatat
     6661 aaatgcacgt ggcgaccgtt ttgctaatga tttaataaaa atgtcaaaaa aaatcattac
     6721 tttgtctttt atttatgaag acgaaaaaac atatgaacaa ttaaatctgt ttcaaaaatt
     6781 taaaatcgat aaagtgaatg aaacattatt aataaaggtt tctgaagaat ttgaatatat
     6841 acttaattca atcggaacta attttactcg tttcgaatta gaaaatatga caaacttaaa
     6901 gagtagctac gttaaagagt tatatcgcca acttatggct cataaagaca gaagatctaa
     6961 aaaaggtcac tggtttgtaa aaatagaaga ttttagagct ctattagcaa taccagaaag
     7021 ttatcgcatg agagatattg ataaacaaat ttttgcccaa gcgaaaaaag aatttttaaa
     7081 cgttaattca actcaccctg ctatttttaa aacttttgaa atcaaaaaaa ttaaagccta
     7141 caaaggaaat aagataggat ctctgcaaat ttattttgaa gaaaatatac cttcaattac
     7201 cttagataat tggttagaga aataatacct aacaatttag gaggcaatta tcatgcaacc
     7261 caaagaaacc tttacaataa aggaattatc tgaattattt gaaataagta ggcaagcaat
     7321 ctctaaacat gttgataaat tagacccgtc cttattagct aaaaatgagc gtggttataa
     7381 ggttgtatta cgttctggag tattgcaact tgctagcaac ttaggtaacc aaaggttact
     7441 atataggttg catgagtatg aacaagaaaa cgataaaaac gtttatatat caagcaaaaa
     7501 cgtgattgta aacgagttgc tagataagtt gcgtgaagaa aatgaatttt tacgagaaca
     7561 actttccctc aaagagcaaa ataattctaa tatgcaaaaa ttactcgacc agcaacaaca
     7621 gctcacccta caggcaaatc aacagatcga aaaactgcaa gaacagttac aattagctta
     7681 tacggaagaa actccagaag atgaatcaac tactattctt tctgaagaaa cagaatcgat
     7741 agaaaaacac acaaaaaaga agaagcaaaa atggtggcaa ctttggaaat aactggaggg
     7801 aacattcatg acaagaaaaa atcttctatt cggttctatt ttactaggaa ttctaggctt
     7861 cagtccgatg ttattgtcag taatcaataa agggaataaa catggtgaat tgaaattgaa
     7921 tccaaattat tacaacagtc ctaacgaaga attgtttgta aaagagacgg ataaataata
     7981 aaaaagactg ctcttccgag cagccagtta aaaaataatg agtgtttatt cttgaaaaag
     8041 cacgcgctta tgaagcgcta ccaaaaattt accatatttt acaaaaaata acaagtctta
     8101 aaaaaatgac agataaaaat gcacaaagaa ttagatatag ataaccgcga aaaatcaagc
     8161 tttagaaagt tgcttttagc tagaccaatt aaaaatcaca aagtgagcgt ctctatccat
     8221 tggtagaggg gctacttggc atagtgtaca ttatgtcaac tatgcaatta aataactaac
     8281 tacttcatat tagcttaata aaataatcaa aataactagg gggaaaaaca ttgtataaaa
     8341 aaatttttca ttttttaaat aagaatagta aatataaaaa taatttaaga tatctattac
     8401 tattaatcca gatagagcaa accaagtaaa tattccatgt gtaaagctaa aaaaattcat
     8461 ttgaatcaat tcaaataaac ctaatatagt aacaaatata ttaaaaataa tagctgtcaa
     8521 taccagtaaa ttattttttt tattttttga attatcttca tttaaaatag aatttatgtt
     8581 agtactataa aattcacaaa ttttttttag tgtctctata tctggtgttg ttttgttatt
     8641 ttcccacttt gaaatagttt gacgtgtaac gttaaatttt cttgccacat attcttgagt
     8701 ataccctttt ttcactctta attctcttag cttagatcct aaatcctcca ttttttctcc
     8761 tatgtaaacg attatttaca taaaatttta tcataaaaat actaacgcgc caaaaaagtt
     8821 ctttatttta taaaacacac taaaataaaa taattctagt aaaaaagata ggagaaataa
     8881 gttatgaaaa aatttttatg tctttctgct ttaatgggtg tcttattaac tagtggagga
     8941 atagctagtg ccacagaagc tttaaatcta gatgtacccg aagaccatac cgccatttac
     9001 ggaggaggaa tggaagctac agaagaagga ttttcttcta gtaaattgag atatgctgct
     9061 ggcggcgggg atttcaactg tggggttaat ggatttaaag tttatgcaaa ttactaccat
     9121 gctagagcta aacatagtgc aacagctaaa aatggacgag gcggtcaagt acgatcagtt
     9181 cagaaagctg gagtaagagc ttatgcaaca tgcaatgcca cacttactgg aaatactggt
     9241 tggtggaatg tttattaaaa aagagagttt aaactctctt ttttatttac atttgaaagg
     9301 aaattcaaaa tatgtt
//
LOCUS       DARPZJ010000079         9106 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.082, whole genome shotgun sequence.
ACCESSION   DARPZJ010000079 DARPZJ010000000
VERSION     DARPZJ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.082"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(51..1517)
                     /locus_tag="SLE23_002504"
     CDS             complement(51..1517)
                     /locus_tag="SLE23_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HEI8469355.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1904..2500
                     /locus_tag="SLE23_002505"
     CDS             1904..2500
                     /locus_tag="SLE23_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEI8469356.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2558..3040)
                     /locus_tag="SLE23_002506"
     CDS             complement(2558..3040)
                     /locus_tag="SLE23_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469357.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3146..3343)
                     /locus_tag="SLE23_002507"
     CDS             complement(3146..3343)
                     /locus_tag="SLE23_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469358.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3638..4396
                     /locus_tag="SLE23_002508"
     CDS             3638..4396
                     /locus_tag="SLE23_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEI8469359.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4456..4884
                     /locus_tag="SLE23_002509"
     CDS             4456..4884
                     /locus_tag="SLE23_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469360.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4930..5002
                     /locus_tag="SLE23_002510"
     tRNA            4930..5002
                     /locus_tag="SLE23_002510"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4963..4965,aa:Gln,seq:ctg)
     gene            complement(5152..5523)
                     /locus_tag="SLE23_002511"
     CDS             complement(5152..5523)
                     /locus_tag="SLE23_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEI8469361.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5738..5923
                     /locus_tag="SLE23_002512"
     CDS             5738..5923
                     /locus_tag="SLE23_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469362.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6006..6194)
                     /locus_tag="SLE23_002513"
     CDS             complement(6006..6194)
                     /locus_tag="SLE23_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469363.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6218..6481)
                     /locus_tag="SLE23_002514"
     CDS             complement(6218..6481)
                     /locus_tag="SLE23_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469364.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6639..6896
                     /locus_tag="SLE23_002515"
     CDS             6639..6896
                     /locus_tag="SLE23_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HEI8469365.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6967..7158)
                     /locus_tag="SLE23_002516"
     CDS             complement(6967..7158)
                     /locus_tag="SLE23_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469366.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7299..7619)
                     /locus_tag="SLE23_002517"
     CDS             complement(7299..7619)
                     /locus_tag="SLE23_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469367.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7642..8076)
                     /locus_tag="SLE23_002518"
     CDS             complement(7642..8076)
                     /locus_tag="SLE23_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEI8469368.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8411..9049
                     /locus_tag="SLE23_002519"
     CDS             8411..9049
                     /locus_tag="SLE23_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEI8469369.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         2898 a         1815 c         1464 g         2929 t
ORIGIN      
        1 aaaaacagga actgctgcaa ataagcaatt cctgttttta tgttcattga ttaatgaata
       61 gagcccatta gttttttgat tggttctttc acagtaaata gcaagatacc accgacgatt
      121 gctactgcac cgataatacc gaagtaagca gattctgttc ccggtgtgta gaagcgtgca
      181 atttgtgcat tgattgcttg tgaagaagca tcagctaaga accaaatagc gattgtttgt
      241 gattcaaatg ctcgtggtgc taattttgtt gtcacagaca aaccaactgg tgaaagacac
      301 aattcagcaa taaccacgat gaagaaactt cccaacaacc acaatggact tacttttcca
      361 cttgtaccat aaagcatacc cggcaacatc aatagcaagt acgataatcc tgcaaataaa
      421 agtccaagag agaatttcac tactgtagat ggttgacgtt caccaagttt cgtccacatc
      481 gttacgaata ctggtgtcag aataaagatg aaaattggat tcaatgattg ataccagctt
      541 gcttggatcg ttacaccaaa tagcgtagat tgtgtacgtt cactagcaaa taaagctaag
      601 atagatgaac cttgttcttg taatgaccag aaaatgattg ctgcaaggaa taatgggata
      661 taagcccata ctcttggttt ttcttcagca gttacatctt ttgaagtcag cattttgata
      721 aagtaataca acggtaagat aatccccaat acactgattg tattgacaaa aaagtcaatt
      781 gtcagatgac cagttagttg tgccccgccg aataccgcag cgataacaac aagtgcgatg
      841 atcaagttac ggatgaatcc tttacgttct tcagttgtca aaggattcgg cggtgttgta
      901 cccactccgt ctaatgtctt gcgtccttgg atgatgtatt gtaataatcc aaagaacatc
      961 ccaatagcag ctaaagagaa ccctaaatga tagttatatt cttgaccgat tgtaccaacg
     1021 attagtggtg ctaataatgc ccctaagttg acacccatgt aaaaaatcga aaatcctgca
     1081 tctcttcgca agtcagtctt tgaataaaga tgtccgacca tgccagaaac atttggtttc
     1141 aaaaaggcgg ttccgataat aatcaatgcc atcgaaacaa acaatgtact tacaccaaat
     1201 ggtaaagcca agacgatgtg gccaagcata atgaaaactc caccgaagaa tacagtgcgt
     1261 tttgctccta acactcggtc agatacccat ccgccgacga tactagacat gtagatcaaa
     1321 gatccgtaga tcgacatgat agctaatgct gttgctcgtg gtaatccaag tcccccgttg
     1381 gcaactgtat cgtacatata atagataagt aatgcacgca taccgtaata actaaatcgt
     1441 tcccacatct cagtgaagaa caaagttgac aatcccttcg gctgcccgaa gaagcccttg
     1501 tcttgctgtt tttccataat ctatacccca attctttaaa ttttcagaaa atattataca
     1561 tctttaccga aaaatttaac taaaaaactt atttaagaaa tataaactaa ttttctataa
     1621 aagcaagtaa tttttaatgg caatatcata aaaaaaagaa gatagagatt taataattat
     1681 atatcagctg tttttttcaa ataagcaaaa attcctaaaa cacaacaatg aaagcgataa
     1741 ctaagaaaat ccttacataa cgatttttct tattaaaatt gttttttgaa cttcgcttat
     1801 tttttgtgag catatctgtt tacttacttt ttgtaaggtg ctatacttca tttcgtaatc
     1861 aattaaaaaa atgcaaaacg caaatcaaag gagaaatttt attatgacaa cttttactga
     1921 cactttgaaa aaccgccgtt caatctatca tctaggacgt aatgtttcac tttctaatga
     1981 agaattaaca actttgatca aagaagcaat taaagaaagc ccaactgctt tcaatgctca
     2041 atcaacacgc gcagttatcc ttttcggaga tgcacatgaa aaactttggg aaatcactga
     2101 agaagcactt cgcccattga ctccagcaga agctttccca aatacacaaa acaaattagc
     2161 tggtttcaaa aatggttatg gtacagtatt attcttcaaa gatactgacg tggtaaaagg
     2221 tctacaagaa caatttgaat tatatgcaga caacttccca gattggtcag aacaatcaaa
     2281 cggaatcgca acagctaata cttgggtagc attagttgat aaaggattgg gcgcaaactt
     2341 gcaacattac aacccagtta ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa
     2401 ctggaaacta cgttcgcaat tagtattcgg ttcaccagaa acaccggctg gggaaaaaga
     2461 atacatgaac gatgccgatc gcttccgcgt atttggataa ttttatttga aataaaaaac
     2521 agaggttgtg acaaacatct tgtcgcaacc tctgttttta ttctggatca atcataatat
     2581 caatctctgc ctcatcgttt aagcgttggg acaaaaatgg aactaattct tctaatgatg
     2641 cagaaaattt cagcatcggt cctcgccatc cgtttcggaa aaaattcatt tttacgattt
     2701 tagaaccttt tggctgatat aatacaattt tattgatctc agaaaaagga acaccttttt
     2761 tgtcaaagct attcaaaaca agtccttctt ctgtgattcc tctactgtcc aacaaaaaac
     2821 taataaaaat cattgctgac aagatccctt ttgccaattc atctgctgta ggatgactga
     2881 tgagtgtata ccaaatgact agtgacacta agaagggtat caccaagtag acccatcgat
     2941 ttcgcacagt ccgataaata atttcttttc gaaccagcca aagaaataaa aacatcacaa
     3001 caacgaataa aaacaataga accgtaaaga atgttaccat gacaactcgc ctcgcttttt
     3061 cttctccaga aaataggaaa agaatactga tttaccttct caaagaaatt ggacttgcag
     3121 cacgccgcac gtccaattgt tttctttatt caaatgtatc atattttgca acaaccatgc
     3181 ttgctttttc atctaataat tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg
     3241 cgcagtttgt catttttgat acaacttcac caatgaccgt ttttgtaaaa ccaattggtt
     3301 tgcatgcata ttgttctcct aaattaatca tttcttccgt catcaaaatc ctcctaaact
     3361 gctggaactt ttctccacat taccactgct atttctttgg agatttaact cattgatttt
     3421 tatttacagt taaaaatcaa ccttacaggc attatagcgt actgttttcg ttttcacaat
     3481 taaaacagct gttgtattta gaagaatttt tttcaaaaaa ttaaaacata ttccttaaaa
     3541 actaattatt tcctacatat taaaatataa tacttccatt tccaataaaa atacatttat
     3601 aataggaaag ataaacagct gaaaagggag atttcaaatg aagaaaaaaa cgttcaaaaa
     3661 actattgttt ctagggggca cagctgctct tttattaagc ggtacaagtt attacctaca
     3721 tatccattct ccagaacata caatgaacac tgcacaaaaa agttcaacac aaaaaacgaa
     3781 aaagacaaaa gagaaagcag aagttttact agatgttcca ttagagagcc agtttgattc
     3841 tccttcttta gaaaatggct gtgaagtcac ttcgctttct atgcttttat ctttttatgg
     3901 ttatgaaaca actaaaaacc agttagctga gcaattggat tacgtccctg ttttcaatgc
     3961 agatgggact catggcgatc ctaatgaagg atttgttggt gatatcagtg gcggagactg
     4021 ggctatggtc gtctatgttc ccccagttgc ctcccttgct cagcaaatcg tccaaacgga
     4081 ttatcacact tttccaaaaa ccgatgctca actcgatgat atcaaaaaag cactatctaa
     4141 aggaaatcct gtctggactt ctgtgactat caattttgaa gtcccagatg aaactgattt
     4201 tatgacttgg accacaaata atggagaagt aagagtcact cctcttgttc atgcttgtgt
     4261 agtcactgga tatgacaaag aaaatattta tgtcaacgat ccctatggtg taaaaaatcg
     4321 agcagtaccg atcaacgatt tttcggcgat tttcactgca atgggtggac agatgctaac
     4381 tttggagaaa agctagtaat tcaaacaaaa atcccttata ctcaagatac caaacctttg
     4441 aagggagcgt agataatgga aaaattcaca cataaaaaaa tggatccaaa tgaaattccg
     4501 attatttttg tccgtgactg caagggaaat gttcaaggta aagtctctat taatgagtgg
     4561 aacgagcgtc gcagacctgc taccctcaat gaactggaaa tcaaattgta tcgtcaatct
     4621 cttgtttatt acgcagatca agagtacgag aaagccaccg atttattgaa atttctaatt
     4681 gctcgaacag agtatactcg ctttgaatat attgaacgtt tagcaaacat ctatcatatt
     4741 atgaatgaac ctgtcaaaga atatcagtta ttggacaccg tcttgtcagt agcagaactg
     4801 attgcccttc ctgctggatt agaaaagaaa ctagtacgcc gccttttacg agtaaagcaa
     4861 caactatccg atcaagaaaa ataacttgcg tttttttagg aaagtgctat gattattttg
     4921 ttgaataaat gggatgtagc caaactggta aggcacttga ctctgaatca agcaattgta
     4981 ggttcgaacc ctgccatccc aatttgatgt gcttgctgaa aaaatgaacc ccctgtaaaa
     5041 gaacaatctt tttgcagggg gattattgta ttatttttac tacttgtatt tagtttacat
     5101 aattaaatta tgaataataa aatcgggcgt attcttaata caaaaactga tttacccaat
     5161 aattgctaat gctttctccg gaactttttc tctaggaact tcctcatacg tttctatgtg
     5221 tgctccttta ttgctaattt tcaaataatg attttctttt aacacagaaa gaccattaaa
     5281 ttcaaccgtt cgttctttcc cattggcatc agcagctttc tgcacatacc ttgctgtacc
     5341 atattcattt acttcctctg gtttttgtgt ctttacatag acctctcctt tttcaactaa
     5401 tggatttagc tgatcaagta taccagggat ttctccataa cttccttcag tataatattt
     5461 cagtccaaat agcaaaatac cactaatcgc cgccagtcca atcaaatatt taatcacttt
     5521 catctttcta cctccttgtt atatattcag tatatgggtc agttaaagaa attccatccg
     5581 tcccaagttg gagatttttc tcctacttta gaagcgagaa tcgagtgttt ttttagtaaa
     5641 aatgatcgtt atttgatatt attgacgtgt ggataaatca gtttttctcg ttttgtccat
     5701 gtaaaaaatc atgttgatag caaaggatgt gttcaaaatg aatcaagaag aattatttca
     5761 aaaagtcaag gaaatgatta agaacggcaa tttcgatggc gcaaaacgat ttatcgaaga
     5821 acataaagaa caattaggac cttataaaga gaaagcccaa aatcttttaa aagatgtaaa
     5881 tatcgacagt gtcaaaaaca aatttaaaaa tctattcaaa taagtaaaac tttcactttt
     5941 gtaaaatcaa aggaggacaa tgctgctgca tcgtcctcct ttggttcttt tctgaatact
     6001 tcatactaaa ataaacgtgt cggatcgtaa tgataagtca cattgccgtt cagtgaggct
     6061 tttcccacca catatttacg attctccaac ttcagccacg cttctcgaaa agccattaat
     6121 tcttctcttt ttacatcaat cttttcgatt tttccatcga tcaaatcttg aataagttgt
     6181 tcatatggat tcattttttt cctccatctg ctgtcaatca ataagttgta aaaataggtt
     6241 catatgcttt tttggtatct agatcttctc tgactttgac tgtcgtataa ataatttttt
     6301 ctactgggat actataataa cttccttcac cattattgaa tcggtgaacg tctttctttg
     6361 ctaaaatacc atttatttta ttcgtcagta cacgttgttc gacactgtta cttacaacat
     6421 agtaaatcac ccgaatatta ttgatcaaat gcaaatcgat ttctaacact acatgatcca
     6481 tgaaaatccc actccttctt tcactttgat tatagcaagt ttctcctcta atttcaaaat
     6541 cgatacagat tttaccggat aaatccacaa aactgcttgc gccatttcgc acaaagtgtt
     6601 attttgtatc atggacttta tttatcggag gcaatagtat gatcgcgatc ggtcaatttg
     6661 ttttttatat tccttttttt attatgataa gcattctttt ctattacata aaatggacaa
     6721 aaaagaagtt ttcagtttta ctggcctctt tacctgctgt atattttact tatcaaattt
     6781 tttcttttag gcattgggaa acaacgtctg tattaataac acacatcatc gaattgacgc
     6841 tttcagtaat ttttcttatt atttggatct attttttata taagaatcag aattgaatcc
     6901 ctcgcatgtt taaaaagaaa acgattaaag atgcagcaaa tttctgccga tctttaatcg
     6961 ttttttctat tctgttatac caaaaaaatg tttgaatcgg tgaaggatcg ttccttgttt
     7021 taattctata aattcttgtg cgatcgggta cttttcttcc aaattttctt tgttcttttc
     7081 gatcaggctt ttcgcttctt catatttttt atctgcacat agtgctttta cttcctgtaa
     7141 tacttttcct gcttccattt gcctcaccct cttgccattt tattgcttta agttttattt
     7201 aagttatacg cattattcta gtttcatccc aaataacctt ttttcatttt tactcctcga
     7261 actaatcagt tttctaaagg ctgattggtt cgtctttttt atttttcctc catttcattc
     7321 tgctcttctg ttaatttatc taatgctttg attgatgctg cggctcttgc ataatcatag
     7381 ctgtataatt ccataaattt atcaggcaga acaaaccacg ctggatgata accgttagct
     7441 gtgacaggga atcctttatc ttgttggtta tctccatccc atctcagagc aacacctttt
     7501 tttcctttcc actttactaa agcgatcgag tatcccttct ttgtttgtgt gccgtcttca
     7561 ataattgcta aaatttctat tttttctttt ggcgcacgga cttcttgagg acgaaccatt
     7621 ttctattcct cccttatctc attacttcac gaccaacaca ctgcaagggg catgtgatac
     7681 gacataagaa gcggtcgatc caactaatgc ttgttgtata gcaccttttc ctgtcgctcc
     7741 cataacgatc aaatcaatat tttcttgtcc agggatgaca ttggcaatca aatttcttgg
     7801 atctccagtt tcaactattg cgtggatctc agcaatgccg tactctttgg catcattgat
     7861 ttttttcagc atggctactt ctgttctttg tttttcatct gcatagattt ttgaaaaggc
     7921 ataggcacta tgggtcagct caactttgtt gatgattgac acgataaata agtgggcttc
     7981 attgtccttt gctaagtcaa gggcttcagc gaacgctttg atcgattgtc ttgatccgtc
     8041 aactgctacc atgatgttct ggtatctttt actcattgga accgcctcct ttttctttta
     8101 ttgtaacatc tcaagcaaaa atacaaaaaa tatacgcaat atgtaaataa aatgatgaac
     8161 aaaagcaatt tctttcaagt tatttataca tttcttttct catcagaaca cctgttctaa
     8221 tcccattatt tctgcattat gtgaaattcc tcatcatttt tcacatcgag cgaacatcat
     8281 tctgttacaa aaaacgtgga tttgtcataa attgtcatgc ttcttttacc tatgaaatat
     8341 tttcacgtgt taaagtattc ctcgttgaac acaacaaata aaacttttta acgaataaag
     8401 gagatttttc atgacatcac ttaaaacttt actttttgga acaactttgg ctgccggcgc
     8461 tgcattcttc atgggaacga ctgctcatgc ggacgaagct tataccgttc aatcaggtga
     8521 tactctatca acgatttctc aaaaatacgt tggtgataac tccttgatca atgccattgc
     8581 agaatcaaat tcaatttctg atattaacct gatctactca ggacaacaat taacaatccc
     8641 aacagaaggc tctgcacaag cagctgctga acctcaagca gccgttcaag aagcaccagt
     8701 ccaagctgaa cctgttcaag ctgaacaacc tgttgtacaa gaaacggttc aaacggaaac
     8761 acaagcagcg cctgttgctg aaacacaacc tgctcctgct gtaacagaaa ctgctgctac
     8821 tccagcaagt acaagctctg caaaagaatg gatcgcacaa aaagaatcaa gcggttctta
     8881 cacagcaacg aacggacgtt acatcggccg ttaccaatta gattcttctt acttaaatgg
     8941 tgactactct gctgcaaacc aagaaagagt agcagaacaa tatgttactt cacgttatgg
     9001 ttcttgggaa gcggcgaaag cattctggga agcaaacggt tggtactaag attcattatt
     9061 tgaacgttta aacacattca aaatatagta agaggtcatg cgattt
//
LOCUS       DARPZJ010000080         8969 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.083, whole genome shotgun sequence.
ACCESSION   DARPZJ010000080 DARPZJ010000000
VERSION     DARPZJ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.083"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(57..350)
                     /locus_tag="SLE23_002520"
     CDS             complement(57..350)
                     /locus_tag="SLE23_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HEI8469370.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(378..1043)
                     /locus_tag="SLE23_002521"
     CDS             complement(378..1043)
                     /locus_tag="SLE23_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEI8469371.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1183..1815)
                     /locus_tag="SLE23_002522"
     CDS             complement(1183..1815)
                     /locus_tag="SLE23_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8469372.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1822..2889)
                     /locus_tag="SLE23_002523"
     CDS             complement(1822..2889)
                     /locus_tag="SLE23_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEI8469373.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2886..3617)
                     /locus_tag="SLE23_002524"
     CDS             complement(2886..3617)
                     /locus_tag="SLE23_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEI8469374.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3786..4265)
                     /gene="greA"
                     /locus_tag="SLE23_002525"
     CDS             complement(3786..4265)
                     /gene="greA"
                     /locus_tag="SLE23_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEI8469375.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="SLE23_002526"
     CDS             complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="SLE23_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEI8469376.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5780..6949
                     /locus_tag="SLE23_002527"
     CDS             5780..6949
                     /locus_tag="SLE23_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEI8469377.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7216..8850)
                     /locus_tag="SLE23_002528"
     CDS             complement(7216..8850)
                     /locus_tag="SLE23_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469378.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2856 a         1701 c         1333 g         3079 t
ORIGIN      
        1 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
       61 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
      121 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atcaatttcc
      181 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
      241 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
      301 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
      361 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
      421 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
      481 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
      541 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
      601 gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa attatgcgca
      661 atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat cttttcaagt
      721 actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc catttccttt
      781 accatcagag taactaagat actggcttga atatcttctc caatagcgac aattacatga
      841 tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt tgccacaaca
      901 gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc aatagccagt
      961 acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg tccaagacct
     1021 acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt ctcagtataa
     1081 caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
     1141 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
     1201 tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag ccaatatatt
     1261 ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta tttcctgatt
     1321 actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta gttcttcatg
     1381 taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttctggttc
     1441 taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat gtgcggtaga
     1501 ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt tttcgtcatc
     1561 aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga ttgcttttgt
     1621 tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt ccggtcgaag
     1681 tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta cttcaatgtc
     1741 ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt catctactaa
     1801 taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga tttctacact
     1861 tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
     1921 tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa accctgttcc
     1981 gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata cctctaattc
     2041 attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc ggaacaagtg
     2101 atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg aaatctggat
     2161 tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt tctcttctaa
     2221 attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
     2281 ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt tttctgcttg
     2341 ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa ctgaatcatg
     2401 cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg tttgtccatc
     2461 tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa tcattttttc
     2521 ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg atgcacttgg
     2581 gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac gcagcttttc
     2641 ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga caattaatcc
     2701 tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata aacgtgcacg
     2761 cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga aaagtgaaaa
     2821 tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc tggatatttt
     2881 tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat aatcttcaat
     2941 ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt tttcaaagaa
     3001 aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa tcggatggct
     3061 acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
     3121 tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga aatgacggcg
     3181 atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc gaataattgc
     3241 tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat catgatctgt
     3301 ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac acctttcaga
     3361 ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt gactaagcta
     3421 aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt acgaggatgt
     3481 ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa aagtccagta
     3541 ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac cacaaaaaaa
     3601 cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc atcataccta
     3661 tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa atctaaaata
     3721 cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta gatctttcag
     3781 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggagtagca
     3841 atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg agaatcattg
     3901 gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta ctcttcttct
     3961 tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc atctgcatct
     4021 acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt tgtgattctt
     4081 ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc ggaaagatct
     4141 ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac tgtttttagt
     4201 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
     4261 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
     4321 atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct aaaaatgatc
     4381 aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa ttccatatgt
     4441 tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
     4501 tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg attgtcaaaa
     4561 ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac agctgtatct
     4621 tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat atctgactga
     4681 agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt acgatcattt
     4741 tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg tacagtcaaa
     4801 tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt gttcaccatt
     4861 tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc tgggaataag
     4921 taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa cagttctggg
     4981 aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa aaattctttc
     5041 ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc gtacccttct
     5101 ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc ttcttgcaac
     5161 tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc agcttgaaag
     5221 ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt aataatattg
     5281 tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat ctcgacttgg
     5341 actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata acgatacacg
     5401 gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa aatgatcttc
     5461 ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
     5521 gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca
     5581 actcctcctt actatcaagt tcgtaacttt attcattata catgatattt gaattggcgt
     5641 gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt actataagat
     5701 taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt aaaaaagaaa
     5761 ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa aatattcatt
     5821 tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa ctattcttgg
     5881 atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat cagctcaaaa
     5941 aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc aactattaag
     6001 aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca tcatggaaaa
     6061 aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc tttattatca
     6121 gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag tcgagcgtgg
     6181 gcacctttct ttagatacta agctggctca attctatcca caaattgctg gcagccagca
     6241 aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg cttctccaac
     6301 cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa aatttacaga
     6361 ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa ttttgatcaa
     6421 attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac ctttaggatt
     6481 acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac tatcctatca
     6541 aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag agatccataa
     6601 cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc tgtttacaca
     6661 agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc gtgaaaatgc
     6721 gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc tgtcgcaagg
     6781 aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg atgctatcat
     6841 catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg atctaagaaa
     6901 ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat atgatgaaaa
     6961 gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg actaaacgta
     7021 ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa ttccaaataa
     7081 acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa gatttctctt
     7141 taccaacatt atttgacaaa gggcctatta aatctaaaat agtatcttta gattgctaaa
     7201 atatgtgcta gcaaatcatt catggcttgt tcttattttt aattttatgc aataaaaaag
     7261 aagaacaatt agcgtgatta tagaaataaa taatgagatt ttagaaaaaa atgtgtatga
     7321 atacctgatt gttactttat ttattccact ttcacttttt actgtaacaa aaggacctcc
     7381 ttgttttagt actgtagcat tttttgaatt aacagtaacc gttaatcctt tataccggaa
     7441 tacaggtaaa actattgttt tgccttttga agatttaagc gtaaatgtaa tttcatcttt
     7501 atttggagaa aagctactat aaataacttg accatcttct gtaacttgat ggtttttcaa
     7561 aagcaattga tcttttttat agcctatagg tacataatca aaattctcaa attcttcaag
     7621 tttattttcc atttgttcat tagaataagt tccttgaaaa ttcatttctt tcaccatgtt
     7681 aactactgat gaataattta aaattgaaat agctaatatt aataatagta taaaatttct
     7741 tctccttgta taagaaaatt tttccaactg tggagaaata aatagagata ctgaaaaaga
     7801 tatgaacaat gttgaaaata tcataaaacg ccaaggagct tgaataatat ttaaaggagt
     7861 attttgtaag gcaaaccatg gaaatatttt tgtacaaagt agaatagata ttatacccat
     7921 tatataagtg attttagata agattcctaa ttttttaaag ttaaatgtta gtataattaa
     7981 acaaataagc aaagttaagc caataccaaa tgatagtaat tctgaatcta tacttccaat
     8041 caaaaactct ttacccagat aaattgctct tttttgtaat atatccacat aaggtctatt
     8101 cagatcttga tacaatgtct gctcaatcat aggacctata aacgctagtg aaagaagtaa
     8161 agtaactata gcagctttta ttaatttaat aattaagaag atttctattt tctttttccg
     8221 ataaaattga ataattaaag caattataat cattaccata gtcatagcta cagaaagaac
     8281 atgagtgtaa attaataaag tcatgctaat cgccaacata acccaagatt ctttttttga
     8341 gtcgtaaagc tttataaacc cgagtaaaat aagaggaagt attgacattg cgagtaattc
     8401 ccccattgcc cctcgaagaa atatttctac actcctaaaa gaagatgttg tatatataat
     8461 agcgaaaaag gagctagtaa catgtttttt ggtaatttca tacattacat aatgacatat
     8521 aaatagagta atgagcgtaa caatataaag aaaaaggtta tagcctattg ctaaattagt
     8581 aaacttgatc aataaaaata aaggatatag agttaaccat gggtaaaaat tatttacttg
     8641 catgccatat gatctaaacg tttcaaaatt aataggggag ctaaaaatag attctaaact
     8701 taacgcacga ttaatgtgaa atgccgtatc ataaaagcca aatatttcca tgtttttaaa
     8761 tgctggaaat aaatataata aactaacaaa tgcataaact ataaatattt ttacagaaaa
     8821 aatttttttc aaattcatat accacctcat gtttttttat attacatata gtatcattta
     8881 tttttttaaa acactagatt agtcactata taaaatgtga ttaattttat tattaataaa
     8941 atatttttta tattacaaaa gtagtgttt
//
LOCUS       DARPZJ010000081         8818 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.084, whole genome shotgun sequence.
ACCESSION   DARPZJ010000081 DARPZJ010000000
VERSION     DARPZJ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.084"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            161..391
                     /locus_tag="SLE23_002529"
     CDS             161..391
                     /locus_tag="SLE23_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEI8469379.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            488..1789
                     /gene="murA"
                     /locus_tag="SLE23_002530"
     CDS             488..1789
                     /gene="murA"
                     /locus_tag="SLE23_002530"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEI8469380.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1802..1978
                     /locus_tag="SLE23_002531"
     CDS             1802..1978
                     /locus_tag="SLE23_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEI8469381.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2113..2409
                     /gene="yidD"
                     /locus_tag="SLE23_002532"
     CDS             2113..2409
                     /gene="yidD"
                     /locus_tag="SLE23_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEI8469382.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2594..3061
                     /locus_tag="SLE23_002533"
     CDS             2594..3061
                     /locus_tag="SLE23_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8469383.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3146..4030
                     /locus_tag="SLE23_002534"
     CDS             3146..4030
                     /locus_tag="SLE23_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8469384.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4144..4380
                     /locus_tag="SLE23_002535"
     CDS             4144..4380
                     /locus_tag="SLE23_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEI8469385.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4468..4548
                     /locus_tag="SLE23_002536"
     tRNA            4468..4548
                     /locus_tag="SLE23_002536"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4502..4504,aa:Tyr,seq:gta)
     gene            4555..4626
                     /locus_tag="SLE23_002537"
     tRNA            4555..4626
                     /locus_tag="SLE23_002537"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4587..4589,aa:Gln,seq:ttg)
     gene            4751..4921
                     /locus_tag="SLE23_002538"
     CDS             4751..4921
                     /locus_tag="SLE23_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469386.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5141..5848
                     /locus_tag="SLE23_002539"
     CDS             5141..5848
                     /locus_tag="SLE23_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8469387.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5907..6551)
                     /locus_tag="SLE23_002540"
     CDS             complement(5907..6551)
                     /locus_tag="SLE23_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEI8469388.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6677..6964
                     /locus_tag="SLE23_002541"
     CDS             6677..6964
                     /locus_tag="SLE23_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469389.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7072..7392
                     /locus_tag="SLE23_002542"
     CDS             7072..7392
                     /locus_tag="SLE23_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8469390.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDT
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7473..8786
                     /locus_tag="SLE23_002543"
     CDS             7473..8786
                     /locus_tag="SLE23_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEI8469391.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
BASE COUNT         2905 a         1437 c         1900 g         2576 t
ORIGIN      
        1 tttgtctcag tccctttttt tgcatatttt tagcatttat ttcctaaaaa atgtaagggg
       61 attcctatat ttttaagtat acttgttttt ccttttatac attttatggt attatcattt
      121 tattagttat tataaaacaa tcgttagaaa ggacgtcatt atgcaagtat acggaattga
      181 tgcggtgctt cgaatcgtga gtcatttggc gtttatctac ttagccttct ggtctttacg
      241 ttcgttacgc attgaaactt ttttcagacc aatgcataat acgcaaatta gaatggcaat
      301 cgtacttttt tcaatttttt tagggtacac tgcaagtaat tttttcttag aagttatcgc
      361 tttatgccga aatcttttcg ttagcctgta aattttaaaa aaaggtacta ttttaaaagc
      421 aaggatgtta taatagaaaa gattttgagt aagtgtatgc tcattggaat tttttggagg
      481 gaacaacatg gaagagatca tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat
      541 tgaaggagct aaaaatgctg ttttgcctat tttagctgct agtttgttag cagaagaagg
      601 tattacgaca ttagacaacg ttccgattct ttctgatgtc ttcactatga atcaagtgat
      661 tcgtcactta aacgtagatg tagattttga tgaacaaaag aatcaagtaa caatcgacgc
      721 ttcaagacaa ttagaaatcg aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat
      781 cgttgtgatg ggtccgctac ttgccagaaa tggacatgca aaagtagcta tgcctggtgg
      841 atgtgcgatt ggtaaacgac caatcgattt gcatttaaaa ggatttcaag ctttaggagc
      901 aaaaattatt caaaaaaacg gctatatcga agcaattgcg gatgaattga tcggtaacac
      961 gatttattta gatttcccta gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa
     1021 agcaaaagga acaaccatca ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc
     1081 aaacattttg aataaaatgg gcgctcaagt ctatggagct ggtactgaaa caatgcgtat
     1141 tgaaggcgtg gatcatttac atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc
     1201 aggtaccttt atggttgctg ctgcaatgac acaaggcaat gtgctgattg cagatgctat
     1261 ctctgaacat aaccgcccat tgatttctaa attgatcgaa atgggtgcag aaatcattga
     1321 agaagaaggc ggagtccgtg tcatcggacc aaaacatatc ttacctacag atgtaaaaac
     1381 gatgcctcat cctggtttcc ctacagatat gcaagctcaa atgacagcta tccaattagt
     1441 tgcagaaggt acaagtgtag tgactgaaac agtgtttgaa aatcgtttcc aacatttaga
     1501 agagatgcgc cgtatgaacg ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg
     1561 aaaccatgaa ttgcaaggtg cagaagtata tgcaacagac ttgcgggcag cagcagcatt
     1621 agttttagct ggcttgaaag caaatggaat cacacgtgtg cgtaacttga attatctaga
     1681 ccgtggatat tataatttcc atatcaaact acagcaatta ggtgcagacg ttgaacgtgt
     1741 agacatggat caaacttctg ctgaaaaaac agcacaaacg attgcttaag gaagtggctg
     1801 aatgagtaac caacgatata tcttattaac tttgataaag attttaatgg tgatcttatt
     1861 gcttatcctt ctttttgtgg ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa
     1921 tccatttaaa gtatttcagc caagtttgtg gattcatatt cgagactttt ttcattgata
     1981 aataagaatc acagtggttc tagtcgatat gaagtgagcc atgaagcaga acatgataaa
     2041 agaaaacaga agggaacgtt gacgttagtc gcgatccctt tttttagtaa aagaaaagaa
     2101 ggaatctaat tgatgaagaa gatattgatt tatttagtta gaggatatca gcgctttatt
     2161 tcgcctgcat ttccacctag ctgccgttat tacccaacct gttccaatta tatgataaaa
     2221 gcaattcaaa cccatggcgc gctaaaaggg acggtaatgg ggactgcacg gatcttacgc
     2281 tgtcatcctt ttgtcaaagg cggtatcgat tatgtaccat tgacattccg attaacgcga
     2341 aataagaaag ataaaaaaga accagattat aaaaaggttg tgaaaaatac gggtagcact
     2401 gagcgataaa gaaacaattt ggaaaatagc ttcttatatt ttgcaaaatt gtgagttatt
     2461 gccgaagtgt tggattttga acaccgtcaa aaaaaaggtt gtgaaaaata cggctagcac
     2521 tgagcgataa agaaaaagag gaaatttatt gtcaaagtaa caactccgca actacttata
     2581 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2641 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2701 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2761 cgaaatcgtc aatgtagcag taaccccaac gtatcaagga aaggggattg gcggaaaatt
     2821 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2881 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2941 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     3001 agatcaatta agggatcaag tgattttagc aattcactta cctaaaaata gctttaacta
     3061 ataaaatttc aattcaagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3121 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3181 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3241 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3301 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3361 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3421 aactctgttt caacttccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3481 attttatgaa ggtgctgccc gcgattatca agatgttgct tttgttgtgg caggaactgg
     3541 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttacggtgg
     3601 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3661 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa
     3721 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3781 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3841 cgtattaggc ggcggggttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3901 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3961 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     4021 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     4081 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4141 aaaatgatgt caaaaaaaaa taaagatatt gaagtgcgta tagaagaagt gaaaaaagat
     4201 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4261 atcttagcct atggaccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4321 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4381 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4441 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4501 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4561 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4621 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4681 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4741 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4801 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4861 ccgggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4921 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4981 ctaggttgga catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     5041 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     5101 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5161 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5221 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5281 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5341 tacatatgtt gcacgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5401 aattatggaa tcacaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5461 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5521 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5581 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5641 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5701 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5761 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5821 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc gtattagaaa
     5881 taaaagagaa tcagaatcac ctgtttttat atatgatcag ttaccagttg ctcgtgataa
     5941 gaaacaggac cctcttcaaa ttggacttgt ccgttcagca gctcaatgat ggattcttta
     6001 aagtggtcag cacttttttc atctacagca cagatgacgc taacttgatc agtatattgg
     6061 atttctttta taaaaaaatg ttggagttca agataattct gtaattttcc tagttgcgga
     6121 tacgtgatca tcacagagat ctcctgttgc aaggtacctt ctacgattcc aatgtcagac
     6181 aatgcttgag agaccgcatg agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt
     6241 cctccaaaat atcgagtgac tactgcagct acattgatca gttgattttt tttgaggact
     6301 tccaacatcg gtatgcccgc cgttccactt ggttctccat catcgctgct tcgctggatt
     6361 tcattttttt ctccaatgat gaaggcgctg cagttatggt tcgctttcca atgttctttt
     6421 tttatttctt gaatgaaact ttttgcttcg tcctctgatt ctattcgtct aagagaacag
     6481 ataaagcgtg attttttgat ctcgatctca ctttgtccat tttcttttat tgtacgatag
     6541 cgctcgatca tcttgtcacc tcttttttca ttttctttat tcagtataaa taaagttcta
     6601 ggttgtttca acactgtaac ggttgcgcaa ttgctgtagt atgcgataat aaagacaaag
     6661 gcaggtggat ctggggatgc aggaacgaat gaaaaagtac gatgcaatta cgcattattt
     6721 gaagaacaat ggcggctctc aagtaacgtt gacctttacc caatttgacg aactgctgtt
     6781 tcccagtaac ggacttccca aaacagcaag ggaaagtaca gattggtggg caaatgatta
     6841 taaacaccct gaaaaaggtg cctatggctg gataaatgca ggctatgaag tagttgtcat
     6901 caatttggac aaagaatatg tcgtgttcaa taaattagtg aaatctagtt ggctatttga
     6961 ttaaataaac cgcgtttaga aaacgttgac aaatttcttt ctttttatat aatagagtaa
     7021 cagacgcgaa gaaaacgttt gcgtagtttg ttttaaaaag gagagaaaag tatggctaaa
     7081 aaaacaatca tgcttgtatg ttcggctggt atgagcacaa gtttactagt aacaaaaatg
     7141 caaaaagctg ctgaagcaaa aggaatcgac tctgatattt tcgctgtgtc cgcttctgac
     7201 acagataaca atcttgcaaa taaagacgtg gatgtgttgt tattaggccc acaagttcgc
     7261 tttatgaaag ctgattttga gaaacgtctg gaaccaaaag gcattccttt agatgtcatc
     7321 aatatggctg attatggtat gatgaatggc gaaaaagtgt tagatcaagc aatcacgctc
     7381 ataggtgaat aaatagaaca gtataactat cgaacaagcg atccaaaaaa tagatcgctt
     7441 gttttttcgt atattttttt agggcgaata atatgaatca tttttggggt agaaggcttc
     7501 tgacgagaga tattaaagca atagactgtg aggaggtaaa tttaccaaat tatgagaaga
     7561 tcgcagcagt ggaacgtttg agcaactgga ttctttgtca tcgctgtgga atgagaacgt
     7621 ccgtcattga tggacagctt gcagattacg gttatttttg tacacattgt ctatatttag
     7681 ggcgatgcga cactcaacaa gatttatatt tgtttgatca gcctgaagca aaacctcgag
     7741 aagtcgtctt tttttggaca ggacagctta ctgaaaaaca aacggaaatc tcaaagagaa
     7801 tactttgcca ttcagaaaaa agacatcatc ttatttgggc tgtaacaggt gcagggaaaa
     7861 cagagatgct ttatcctatt ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt
     7921 gtacaccgcg agtcgatgtt tgtaatgaat tgtttttacg ctatcgttat gtttttccag
     7981 aagaaaaaat cacgttgctc catgggaata cagcaacggc ttataccttt acttcttttg
     8041 ttatctgtac gattcatcag ctataccgtt tttatcggtc ctttgattta atagtgatcg
     8101 atgagatcga tgcgtttcct tataacgggg atgcaggatt agctcatgct gtgcaaacag
     8161 cgattaaacc agacggacga ttcatctact taagtgccac acctgataaa aagttactaa
     8221 aggagatcaa gcagacgttt gacatccaca aacttgcttt acgctttcat cggcgtttgc
     8281 ttcctgaacc cgtcttggtt ttcatgaata attggcgaca aaaatgcaag aacaagaaga
     8341 agataaaatc tttggtgcgg atcattcatc aattaattaa agaaaaccat atccttttat
     8401 tttgtccaag tatcacgatg atgcatcgtt tgaaagccac acttcaagag gctcttccga
     8461 gatatgagat cacagatgtt tcttcaagag acaatcagcg ggcggaaaaa gtccagaaaa
     8521 tgcgagaagc aaaatatgac atactgttaa ccacgatgat ccttgaacgt ggagtcacat
     8581 ttgaaagaat atccgttatc gttttaggag cggatcatcc ggtttttact aaatcttctt
     8641 tggtacaaat cgcaggaaga gccgatcgta aagggcctta tacgaacagt caagtatatt
     8701 ttttctatga agaaaaaact gcagctattc gaaaagcttg tcaggaaatc aaagaaatga
     8761 atgaagaagg gaagaagata ctgtgaggtg cagttgctgc agtaaagata tcgtccaa
//
LOCUS       DARPZJ010000082         8661 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.085, whole genome shotgun sequence.
ACCESSION   DARPZJ010000082 DARPZJ010000000
VERSION     DARPZJ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.085"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="SLE23_002544"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="SLE23_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEI8469392.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="SLE23_002545"
     CDS             complement(738..1460)
                     /locus_tag="SLE23_002545"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEI8469393.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="SLE23_002546"
     CDS             complement(1596..2477)
                     /locus_tag="SLE23_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEI8469394.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="SLE23_002547"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="SLE23_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEI8469395.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="SLE23_002548"
     CDS             3717..4196
                     /locus_tag="SLE23_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HEI8469396.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="SLE23_002549"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="SLE23_002549"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HEI8469397.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="SLE23_002550"
     CDS             5497..5625
                     /locus_tag="SLE23_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEI8469398.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5629..6174
                     /locus_tag="SLE23_002551"
     CDS             5629..6174
                     /locus_tag="SLE23_002551"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEI8469399.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="SLE23_002552"
     CDS             complement(6628..8319)
                     /locus_tag="SLE23_002552"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEI8469400.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
BASE COUNT         2410 a         1771 c         1568 g         2912 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaaccca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa a
//
LOCUS       DARPZJ010000083         8492 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.086, whole genome shotgun sequence.
ACCESSION   DARPZJ010000083 DARPZJ010000000
VERSION     DARPZJ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.086"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..173)
                     /locus_tag="SLE23_002553"
     CDS             complement(<1..173)
                     /locus_tag="SLE23_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8469401.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="SLE23_002554"
     CDS             complement(593..1714)
                     /locus_tag="SLE23_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HEI8469402.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="SLE23_002555"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="SLE23_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HEI8469403.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="SLE23_002556"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="SLE23_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HEI8469404.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="SLE23_002557"
     CDS             complement(4304..5215)
                     /locus_tag="SLE23_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8469405.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="SLE23_002558"
     CDS             complement(5232..6239)
                     /locus_tag="SLE23_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEI8469406.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="SLE23_002559"
     CDS             complement(6236..8365)
                     /locus_tag="SLE23_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEI8469407.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8492)
                     /locus_tag="SLE23_002560"
     CDS             complement(8370..>8492)
                     /locus_tag="SLE23_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8469408.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1729 c         1486 g         2678 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattccca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tt
//
LOCUS       DARPZJ010000084         8350 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.087, whole genome shotgun sequence.
ACCESSION   DARPZJ010000084 DARPZJ010000000
VERSION     DARPZJ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.087"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..897
                     /locus_tag="SLE23_002561"
     CDS             <1..897
                     /locus_tag="SLE23_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HEI8469409.1"
                     /translation="FERYQRNEKALMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSF
                     VSSLTEQLEPMVNEWQNRLLSEKNYPYLMTDVLYIKVREENRVLSKSCHIAIGITKDG
                     DREIIGFMIQSGESEETWTTFFEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQ
                     RCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKA
                     CASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIG
                     AVLMDLHDEWIYSSRKYINFDK"
     gene            946..1248
                     /locus_tag="SLE23_002562"
                     /pseudo
     CDS             946..1248
                     /locus_tag="SLE23_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1393..2133)
                     /gene="truA"
                     /locus_tag="SLE23_002563"
     CDS             complement(1393..2133)
                     /gene="truA"
                     /locus_tag="SLE23_002563"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEI8469410.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2324..2959)
                     /locus_tag="SLE23_002564"
     CDS             complement(2324..2959)
                     /locus_tag="SLE23_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEI8469411.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3106..4347)
                     /gene="sstT"
                     /locus_tag="SLE23_002565"
     CDS             complement(3106..4347)
                     /gene="sstT"
                     /locus_tag="SLE23_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEI8469412.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4545..5541
                     /locus_tag="SLE23_002566"
                     /pseudo
     CDS             4545..5541
                     /locus_tag="SLE23_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            5557..7575
                     /locus_tag="SLE23_002567"
     CDS             5557..7575
                     /locus_tag="SLE23_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEI8469413.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(7635..8327)
                     /locus_tag="SLE23_002568"
     CDS             complement(7635..8327)
                     /locus_tag="SLE23_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HEI8469414.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT         2729 a         1610 c         1369 g         2642 t
ORIGIN      
        1 tttgaacgtt atcaacgaaa cgaaaaagcc ctcatggctt caatgttgga aatgtatgta
       61 tcaggcgttt caactcgtaa agtatcaaaa attgtggaag aactttgtgg taaatccgtc
      121 tctaagtcct tcgtttctag cttaacagaa cagctagaac ctatggttaa cgagtggcag
      181 aatcgtttat tatcagaaaa aaattatcct tacttaatga ccgatgtact ctatataaaa
      241 gtacgagaag aaaatcgagt actctcaaaa agctgtcata tagcgattgg aataaccaaa
      301 gatggcgacc gtgaaattat cggcttcatg attcaaagtg gcgaaagcga agagacctgg
      361 acaacatttt ttgaatacct aaaagaacgc ggtttacaag gtacggaact cgttatttct
      421 gatgcgcaca aaggattagt ctctgccatt agaaaatcct tcaccaacgt aagttggcaa
      481 agatgccaag ttcacttcct aagaaatatc tttaccacca ttcctaaaaa aaattcaaaa
      541 tctttcagag aagctgttaa aggaattttt aagttcacag atattaactt agcgcgtgag
      601 gctaaaaatc gattgattca tgattatatc gatcaaccaa aatattcaaa agcttgcgca
      661 tcattggatg atggattcga agacgccttt caatataccg tacaaggaaa ttcccacaat
      721 cgactaaaga gtaccaatct aattgaacga ctgaatcaag aagtacgcag aagagaaaag
      781 attattcgca tcttccccaa tcaaacatca gccaatcgct taattggagc cgttcttatg
      841 gacctacatg atgaatggat ttattcttca agaaaataca tcaattttga taagtagaaa
      901 tggtaaaaac attgtatagc attttacaca ggagtctgga cttgacttac aattgaatta
      961 gataattcga ataataaaaa tactgtcttg acgacaccta tttatcgtta taaagggcaa
     1021 gtggcttcta ttaatggcaa actagtacaa acaaaattat ctaagtttgg cacaactgaa
     1081 ttaactattc ctccaggtat aaataaagtc gttattactt atcagtacac aaaactagca
     1141 attgcttcaa gatatttatc tatcgttact ttgattttat ttttacttta tcgatttact
     1201 ttttctaaac aaaaacaacc gagaagagaa gtacaacatt ctcactagat ttttatttaa
     1261 gaaagacttt ttagctgtac acataaacag gctaaaaagt ctttttttat atttctttaa
     1321 tttgcttcat acattattta acatcgatat ttatactgtg aaacatgcgt ttcatccatt
     1381 atcaaagtat ttttatcgat aataaacttc atccaaaaac agaccttgtg cagggacggt
     1441 ttctcctgca tgttgccgca ctttgctttc aaatatttca tcgattgttt ctatcggcat
     1501 ggcacctgtg ccgatttcta gtaatgtccc catgataatc cgcaccattt tatataagaa
     1561 tccgtctccg acaaaagtaa aatgaagcat ttctcccttt cgttcgatag ataattcatc
     1621 aatcgtacgc actgtggatt tttttgattt tttcaatgca gaaaaaccaa tgaaatcatg
     1681 tgtacccact aatttttcgc aagctgcatt cagcttgtcc atatccaact cttgagggaa
     1741 ataaaagctg tggtttcgct caaatgctga aggaatcacg ttgttccaaa cataatagct
     1801 gtattttttg cccaccgcat tatatcttga atggaagcgc tcaggcattt cttcgattct
     1861 tttgatgaca atatcccgcg gaaggtaacg attcataaag tcgatcattt ctgccagtcc
     1921 aatttctgtg tttgttttaa aatttgctac ttgtcctcgc gcatgggtgc cagcatctgt
     1981 tcttcctgat ccaataattt ctatctcttc atttgtcatc tgatgcaata ctttttcgat
     2041 ttttccttga atggttttat cgtcatctcc aagtctttgc catcctgaat atctttttcc
     2101 gtcatattcg attgtcaact tgatgtttct catattttag tggctcctct gtcttccatt
     2161 tggtcttctc tctacctttt taagattgta gcacaaaata tagctccttt cttctctaaa
     2221 acagaagcta tacaagaaaa ctgtggaaat atatatttca gaaaaacaaa aaacagccac
     2281 cggatgaagt atccgctgac tgttcaattt gacggctcaa gttttactgt ttgagatgca
     2341 agatactcaa ccaggcaatg ggcacataat taaagaaaaa actgattctt tggcaaaaac
     2401 ctattttatt cagtaatggc caagaattta tagaaggaat tcttgccagt ccataaatcg
     2461 ccgcaaaaag caaactgatc acagacagtc caaggtataa gtggcttacg tccatttgcc
     2521 cattttttcg atagatcaag aaaagaagaa ctggaaacaa taaaaaacca ctgtaaccta
     2581 aacctgatcc gatattatgg acccatgtcg agacattcca cgaagattca tgggtattga
     2641 tactgaacaa acctgtaaag atacaatcac ctataccata gaacgcgatg gctgctgtaa
     2701 ctagggtagc taacacacga gatgtactta caaatgcagc atacaatgca ggcaatgaca
     2761 ggatgaaaaa gatccctgaa accacagacc aaataagaaa cgcttttctt acaggactgg
     2821 aaacctctcc aaatacactg atcacgctct tcatttgatc taattcagga taatacaatc
     2881 ctaatacgta cggagtcaaa aaatcactca gcacgcctaa taataaaaag aaaaaaccaa
     2941 atttacgtaa aaaatccatg atacgcctcc aataacaatt acctatgctt ttaattgtta
     3001 ttataaacga ctttatcttg atttaacaga aacctctatt tacacgaaca tctatataac
     3061 tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct aacgttcaac gttcacttaa
     3121 tccatctaaa caatctttca atttgatttt ttccccactt cttttacgcg cgcctagctc
     3181 tcctattgca gtaaacaaca gatcacttga cgaatttaag gcagtttcca ttgaatcctg
     3241 gataacaccg ataataaatc caataccgac gatttgcatc gcgacatcat tagagatacc
     3301 aaacaaacta catgctaatg gaatcaataa cagtgaaccg cccgcaacac ctgaagctcc
     3361 acaagcagct aaagcagaca aaatacataa aaggactttc aaaacaaaag gtgcttcaat
     3421 ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg gtaatcgcgg caccgcccat
     3481 attgatcgta gcacctaacg ggatcgatat ggaataagac tcttttgtca atttcaatct
     3541 ttcagccaac atcatgttta tcgggatatt tgcggcagaa cttcgggtaa agaaagcggg
     3601 aagtgcgctt tctttcaaac aaaagaaaat caatggatag ggattttctt taataaacaa
     3661 aaacgtgagg aatgggtaca caactaatgc gacaaacagc atcgtaccga tcaaaacaag
     3721 taaaagctgc agatactctg ccaatccagc gattccagtc gtagcaattg attgataaac
     3781 caatcctaaa atccctatcg gagcaaatgc aataatcact tgtacgactt gtgacaacgc
     3841 tatagatatc tgatccacca actcttttgt cgattctgaa cgtgctcgaa aagctagtcc
     3901 caacaataca gcccagaata agacgccaag gtaattcgca tcaataagag attgaacagg
     3961 attttgtgtg acattcgtca acatagtaga taaaacactt tccaaacttt gcggtgcttt
     4021 ttcagatact gtttcttgta aagtaatagg aacagtaaaa attgaactta caataactgc
     4081 tacaagtgca gaaagcaatg ttcccactaa atataagatc aaaataggct tcacgaatgt
     4141 cttattccca attttatgct tggcaattga cgccatcgtc aagaaaaaaa ccagaatagg
     4201 tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat attgaaataa atgtccatgt
     4261 ggggaaaaag ataccaaaca atattccgac taaaatacca acaacaatac gttgaactaa
     4321 cgacatatcc aaaaacttct ctaacaaatg accacccttt cacaatttta acaatcattg
     4381 tatcatttta tgcaaagaaa ctaaaggtat aattttctaa aaattctaac aatacaaaca
     4441 accatttctt gctaattttg tactttttct gtctacacgt tgttttttga gatattctaa
     4501 gttaggatgt tattaatggg caacttatca ggaaacgttt tcttatgttt ttgtccaatt
     4561 tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga gagttatggc ttcctgacaa
     4621 tctttgtcgc ttgtataatg atggttttac agcgtatatt gatttcagca gtcactattc
     4681 ctacatatgc aacaaaccct ggtcgattct acatctatac atttttacaa acttccgttg
     4741 ttattggtgc aaatttgatc ccactttaca tgggttacca atatcaaaaa atcgcccgtt
     4801 taaaagtttt acattattta agtcgttttg cctttatatt cctaatagcc acactagttt
     4861 gcaatatctt ttttttacgt acaagctggc agcttgaata ttcgtgatta ttggcttatc
     4921 ctaacaccta tcagtcagaa ttactttact tatgctgttt cttgtacttt gcttttttgt
     4981 agtattcctt atacagttgg atttttaaat aaattatcga aaacaacaat taaatatcta
     5041 ctattatttt taacaattgg attagttggc tgctctactc tatttaataa agacccgttt
     5101 gcattacaga atggacagag tattttatgg attttttatt tatttttaat gggttatggt
     5161 ttgaaagaat ggaactggaa agaaaaggtc cgctataagc ttcctcaagt atttatcagc
     5221 ttgattgttt tattcggttt gattattttg atgacacaaa tttcactcat catcagagga
     5281 aatacagata cagcgctgag gttttctaaa ccatattctc tcttcgcaat gtattatact
     5341 ttctcttcgt ttttattttt agaaatgcta tctgataaat taggtataaa aggaagagga
     5401 aattttcttg ctgtattttt gattgtcact caagttatat gtaatttccc tttagtttct
     5461 tatcgcgtat ctacatttat gaaacgtgaa tttccaaact cagggaaggc atggctgata
     5521 aatatcgggc agttttttat ttgctattta ttagcagtgt ccctcctagt tatcttttta
     5581 ttttatatac aaaaaatccg tttcattcat cgtttcatcg aatacttcgc ttttgattcg
     5641 attgaacaat taactcagcg ttggaaaaaa agaattcatt ggctttttgt tcataaaagt
     5701 tattttttag ttgcagcatt tttttactgc tttaccttcg tgcagatttt cgttttagaa
     5761 ccaaaagaag gttggaaaga aactatccag gttgccttaa aaatatttac tcagcgacaa
     5821 gcacccatga tcctgacaat catcattatt atgggatttt tcttcttact attgttgatt
     5881 tccaatcgtt tttggtacgc cttgactgct accttgatca ttaacttact gctcactatt
     5941 tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct ttccttcaga tttaaaaatg
     6001 ctgaccggat tgtcagaact attatcgatg gttagcccag tcttattaat cgtgggcgga
     6061 ttgatccttc tcctattatt gattactagt attattgtac aacgtagact acaaaaacag
     6121 tattccttga agattcattg gaaacgtcga tttatcagta tcgctgtatt attaggatgt
     6181 ttttcgggtg tctttttcat taatcacaaa aattcgcctt ctttcttgct gtttaattta
     6241 tttaaagtaa acaagacttt ctttaaccag caaggcgccg taaaagataa cggaccagtc
     6301 attcaattcc taaacaatat cgacattaaa atcatggaag aacctgctgg ctattcgaaa
     6361 gaaaaaatta atggaataat gaaaaagtac aacacaaagg cagatgaaat caaccaaaca
     6421 agaagtgact ggttaaacaa tcagacgatc gttctcaatt taagtgaaag cttcagtgat
     6481 cctgcacgtg tccctaatct gacagtacct acagacccta ttccttacat caaaagcatt
     6541 ataacagaag gaacaggagg attgatgtta tccgtcggtt atggtggcgg aacagctaac
     6601 atggaatggg aaggactgac aggcttgagt atcagtaacc tgtctgcttc gttagttaca
     6661 ccttataccc agctagtgga gcgtcagaaa ataagtccaa atattaccga tctattcgat
     6721 gaaaaaatag ccatccatcc ttttacagct gctctttatc gcagaaaaca agtgtttgat
     6781 aaatttggtt ttgacaggtt ctattattta gacagtccgg ataaattaac ttatacggat
     6841 aaaatagaac aaagcccacg catatcggat gattcagcat acaaagaaac cttgaaagct
     6901 ttacaaagca atacagaaac gtcacaattc atccaattat ccactatgca aaaccatatg
     6961 ccttatgatg attactatag tgaattgaac tacactgctg aaggaactgc tgtcattcct
     7021 aatagaagaa aagaattaca aacttatatg caaggccttc actataccga tacagcagta
     7081 aaaaaattca tccaagaaat cgacaaaatc gataaaccga ttacctttgt tttttatggt
     7141 gaccatttac ccgcaatcta tagtgggaat gattcgaaaa aatatggatt agaacagcac
     7201 cagacagatt atttcattta taacaacaag tatagtcgtg aacaagcagc tacgttaaat
     7261 aaagaagttg ttgctcctaa taactttggt gctatggctc ttgagcatgc gaatatcaaa
     7321 gtaactcctt actatgcgtt gttgacagaa gtatctaatc atctacctgc attaacaatt
     7381 gatcctacag aaagcttgtc taatcgtttt aatggaaaac aggtctttgt tacagaggat
     7441 agtcaaatta tccaagaaaa aaatttaact gagaaacaaa aagaaattct agaagattat
     7501 cgtctgatac aatatgatct tgttgcaggt aaccagtaca gtgcaacatg ggcgacacaa
     7561 aaaataaaag actaacaaat aaactgagca aggggttgtg ataaaagaca tgtcacaacc
     7621 ccttgtttat ctcattaatt tgcttgtcca taaacgattt gattaaagcc atttttcaat
     7681 tcattattcg ctgtctcgtt gaagtaaaga taattatcgg gattcccctg attttgttgt
     7741 gtcaccaata cttttggctg attttgctga aacccgaata gatagacgtg ctttttcaga
     7801 tatggttctg tctctgcatc ggaatagacg gctgtgattt gatagtctgc ttgacctgtc
     7861 ccactttctg accattctgc agaaacaggc actccaccaa tagccatctt ccactccccg
     7921 ttcaaaatag cttgagggac tttaagacca tataagtcca cactcatttg attcgtataa
     7981 cttttgtatt gttgtcccat tgtttggccc catttggtca taaatgcctc taattgtgcg
     8041 gatttgtctg cattccacag tgtttgttca acttgttcgc tgctttctga agaggaagat
     8101 gaagcctcta cagaagaact tgaagtagat gtttgagttg tttcagtcgt tttggaagac
     8161 tctgacgaag tagaggtatc tgctgtttct gtacttgctg cagttgactt gctctctgtg
     8221 ctagttgttg tagtagttgc aactgttgct ttcgctgttt cttttgttga ttcttttttc
     8281 gattcattcc cgttggtaca accagctaac aaaaaagcta gaccaattgt tactaaaatc
     8341 ctttttttca
//
LOCUS       DARPZJ010000085         8248 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.088, whole genome shotgun sequence.
ACCESSION   DARPZJ010000085 DARPZJ010000000
VERSION     DARPZJ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.088"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(367..1158)
                     /gene="msrA"
                     /locus_tag="SLE23_002569"
     CDS             complement(367..1158)
                     /gene="msrA"
                     /locus_tag="SLE23_002569"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEI8469415.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1349..1984)
                     /locus_tag="SLE23_002570"
     CDS             complement(1349..1984)
                     /locus_tag="SLE23_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEI8469416.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYRLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2250..3302)
                     /locus_tag="SLE23_002571"
     CDS             complement(2250..3302)
                     /locus_tag="SLE23_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8469417.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3315..4253)
                     /locus_tag="SLE23_002572"
     CDS             complement(3315..4253)
                     /locus_tag="SLE23_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEI8469418.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(4704..5354)
                     /locus_tag="SLE23_002573"
     CDS             complement(4704..5354)
                     /locus_tag="SLE23_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469419.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5454..5963)
                     /locus_tag="SLE23_002574"
     CDS             complement(5454..5963)
                     /locus_tag="SLE23_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HEI8469420.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(6048..6527)
                     /gene="rlmH"
                     /locus_tag="SLE23_002575"
     CDS             complement(6048..6527)
                     /gene="rlmH"
                     /locus_tag="SLE23_002575"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEI8469421.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            6955..8244
                     /locus_tag="SLE23_002576"
     CDS             6955..8244
                     /locus_tag="SLE23_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEI8469422.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENIKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         2617 a         1674 c         1319 g         2638 t
ORIGIN      
        1 tatagttatt gtttgcgctt ttatacggaa tttagttcat cattaatgtg gaattcgatt
       61 aggtgtctat taattatcaa gatgattctc tacaaaattc catagaaaaa tcaagattct
      121 acaattcgaa ttctctttca catggaaata aaggctagta aaaaaacagg agttgtgaca
      181 aaagacttgt catacctcct gtttccttgc gacttgaagc tgaatgcttt gcgccacaac
      241 cttttcctcg gtgttctcaa agcaactcct cgaaataatt cataactgtc caaaaatatg
      301 aaaagctatt tttgtcagtt gctcattatt ttgtcggagc tgaacgcttt gcgccacaac
      361 cttcctctat ctatgtcgct gaaaaaataa atgaagctga tgcgaatgct tgatcttttt
      421 atatctttta ggttgcttct gataaaattg ttgatgatga ttttcagctg gccaaaaagt
      481 ctttgcttgg cgaatctctg taacgatagg acggctaaat cggttagatt gaatcagttg
      541 ttctcttgat ttttcagcca attgcctttg cttttcatta acaacaaata gaattgaacg
      601 atattgtttc ccccgatctt gaaattgacc aaaggcatct gtagggtctg aaatttgcca
      661 ataaatctcc aacagctctt cataggttat ttgacgtgta tcaaatatga tctcaacagc
      721 ttcaacatgc ccagtatatc caccactgac ttgatcgtaa tttggttttt tggtctctcc
      781 acctgtataa ccagataaca ctgagattac acctggtttt gtttcaaaag gctcaaccat
      841 acaccagaaa cagccaccgg caaaaatcgc ccgttcttgg tataagggtg aagttatctt
      901 atgtttggca taatcataag cctttgcact cgctgactcc cctgtgattc ttaaataaaa
      961 atccatcgca tctggtgtca aattatctcg tagtgctagc ggacgcaagt tgacctctag
     1021 tttttctatc acctgcttta tcgacatttt tgctaggtct tcttttgcct cttcaaattg
     1081 tgttctttcc cattctcttg tatttcgatt taaaataata ttataaaggt ctatttccat
     1141 ctgctccaca tctaacatga agtcaccctc tttcaagttt tcttcttatt cattcaaaaa
     1201 atgactacct gaaatttagc acaacgcata acaagttaag actaacttgc ttttcgctct
     1261 cctcatctct attcttagtc gaacacatcc acacgaatgg ttacccatag agaaattctt
     1321 ttacttaatc agcttcacac tgctttttct actttcgtag ttgaaaaaaa cttaaacaaa
     1381 tcatcggcaa atagttaaag aaaaaactta agcgttgaaa gaagcccaat tgcttaaaga
     1441 aggcaaactg actaatcgac ggaatccgtg ctaatctgta aagacctgca attagtaaac
     1501 taataactgt taaaacaaga taaaaatggc taagcgtacc ttgaccactt tgacgataaa
     1561 gcagaacaag taacaatggg aaaagtagaa agcctgcata gcctagccca gaacctatat
     1621 tatggatcca agtcgataga ttccaagagc tttcattcgt attgatactg aataacccag
     1681 taaaaataca atcacctatc ccatataaac caactgttgc aacagcaagt attgcaagtg
     1741 tttttgatgt tccaataaat aggtgataca acgcaggcaa cgaaagaaca aaaaaaagtc
     1801 cagatacaac tgaccagacc aagaaagcac gtctgactgg actatctacg tcaccaaaca
     1861 cactaattac ggtagtcatt tgattcagtt tgggataaaa aaggccaagg atatacggtg
     1921 tcgataaatc actaatcaca cctaataata aaaaataaaa accatatttt tgcaaaaaaa
     1981 tcattttctt ctcctacttt ttagtgatta ttcgatacat ccaacaatca aattttttct
     2041 cattttaaca catattttta ttctagttgc cttttgaaca atcaataaca taaaggtgag
     2101 tttcttctac attttaaaaa atcgaatggc actgaagagt tcagttgtca gcatcaatct
     2161 cctactcaaa aaggcaaaaa aacgtaagtc agatgttgtt gacatctcac ttacgcatcc
     2221 attgattgaa aatttcttag taaaatctac tagcctaaaa atttgaagac ttcttctcga
     2281 tcatacagtt taaatacttt ctcgcataaa aattgagtaa ttagtgccgc aaaaacaggg
     2341 atgactaacc aacaaagaac aacaagaaag ccatttagcc ctgcatctaa agaagccaac
     2401 ggaccaacaa gtccgaccac gccgaaacca gcagaagcag gcgtacctga aatagaaaat
     2461 agagcgacag gaatagctgt aatcactgca ctaactaaac aaggaataag aatcacaggt
     2521 tttctaaata gattaggcat catcatcttc atagcgccta aagcaatcgc aattgtcaca
     2581 cctgacttat taaccttcca agagttcact actaaaacaa aagtggttgc agctacgccc
     2641 atcgcagccg caccagcaga aacaccatct agttggattg ccattccgat tgctactgtt
     2701 gaaataggag agataatcaa aaaggcaaag gaacaaccaa tcaagataga cattaacagc
     2761 ggttgtaagg tagtgaagtt attaatcaat gatccaattg cagaagtaat tgctgttaca
     2821 aaagggaata aataaaaacc aagtaaacct gcacctacac ctacaacaat cggtgttaac
     2881 acaatcgaca ctgacccaaa actatttcca atcagtaaaa tcagcccgac agcaatcgat
     2941 gctgtcagca tcgtattaat aatatcgcct gtaccagcac caacgtaaac acccgtttca
     3001 cccaaatcag gtgtgaattt gactacacca gaaccaacaa aagaagctcc ggctacaacc
     3061 atcattctca tcggatcaaa tccaaattgt aaggcaatca aaccaccaat gatcaaaggt
     3121 gttgctagtt gaaaaataac tgctaactgt gcgatcgtta ccgcaaaggg atacgcacta
     3181 aaatatttta aaatggcacc taatactgca ttaggaatca atccaataat gattcctgtt
     3241 gctgtaccag cgaggacttt attcagaaaa attttcggtg atattttttg tgaagtttcc
     3301 attcaatctc tcctttattt tacgttcaaa ctatcttctt ttgcatggac aagctcagtc
     3361 aagaaatcac aataaggcgt cgcaacacca tatttcttcc cttttctaga aattgcgcca
     3421 ttgatataat cgatttctgt taatcgatgg ttcttaatca agtcttgata cattgaagga
     3481 taatgtaacc caattgtttc cgggtcaaaa caagattcac aatgtgcaat gacttctggg
     3541 acatctagtt caatcttctc tactgctgct actttggcaa actcattgac aatcgtcgcc
     3601 accattttat gagcagtcga tgtttttcct agctcagcca tattaacgtc taagattgtg
     3661 catagtccgt tcattgttcc gttcacacat gctttgcgat aaatagaata gtgaatattg
     3721 tcagaaaaat gagcatttaa tcctgattca gacaatttgt ctgctaattt ttttgcagct
     3781 gcttcttttc catcacctaa attttgtaat tctactgaac cacttccaaa taatttgacc
     3841 tgaccaggac cttcaagacc tgccgtccac atggtatttc caatatagat attttccatt
     3901 ggtacaaatt tctcaataat atcttcatgc ccgataccat ttaatagaca taagacctct
     3961 gtatcttttt tgattaatga ttggatatcc tgcagcattt tttccagctg catcgctttg
     4021 gtaaatagaa taatcagatc aacttgatct tctttttcta cttcggattg aagaacgatt
     4081 ggtagttttg cttctacctc tttaccatta aaatttgctt gtaatccatg ctctttgatt
     4141 tgttggacat gttctgccca gccatcgatt aataatactt cgttcccact ttggtgaagc
     4201 attaacccaa agcgacttcc cattgcgcca gcgcctgcaa ttgctatttt cattgattct
     4261 tcctcctttt tctttctatt atattcattt gagaatcatt tcacaacctt gttttgttat
     4321 tcttctctta tttatcatgt ttatatccac cattcaagtt attttatcag caaatcaata
     4381 aaaactggaa tagaatccca atttcatcgt aagagaaact agactagcaa taagaaaata
     4441 gaaacattca tagaaaaaac ctcactcctc tgattataaa agagggggca ttaacctcgt
     4501 gtatactaaa accttccatt cattcgatgg atgattttct ttttgtgaaa aaatattcat
     4561 tgtagtacga tgttgcgcaa cacagacgga tggtattgct tattatttat taaaatcgaa
     4621 caatacactt atttaaaaac ttctttccca gattttcttc catttttaca gttataacta
     4681 gtattatcat gaaaaatagc cttttattgt ctatgggaat aataatttaa aattggtact
     4741 tttttattaa ttagttcatc gcccaataat ctctccagtt tcttagcatc tcctgactca
     4801 accggaatta tccaagccca gtccaaataa ttttttaaaa tctcatcata ttttgcaaat
     4861 atttcattgc catattccgt ccttaaaatt atattttcag tgccagacaa gtgatttgta
     4921 ttgagttgat aaaaaagatc tccatctaaa aaaatatcat tagaagaaga tttccccaca
     4981 gtaatgacca ttccatcagc tctatgtgtt acatacaaat aattgtatga cctcatttca
     5041 cctaatgaat caattatttc ttgcccttta gctctaatat attgatctct attacctatc
     5101 tcactcttat ttaacaaaag ttttttcatg tcaaatttaa tcggctgttt tatttttgta
     5161 aattcgcttc tactactaat ccaatccgag attaattttt caacatgtcc cagagtaaac
     5221 tctgatttat tcgctaaata ctttttttgt tgtattaaag acatctttcc ccgaagctca
     5281 aaattgagcc tacatcgatt ctctatctct tcaaaaagca tcttatcttc atcattctta
     5341 tattcatcat tcataaaacc aatccagctc ctcgattaag ataatatttt aatctcatac
     5401 aaaaactagc tctcatcaaa acaaccattg ttttgatttc tcatgaaatt tctttatact
     5461 tttctccgat tataaattcc taaccccttg agaaaattac gcatatattt atctccgcaa
     5521 ggcttaaaat ttcgttggcc ttcttttctc aaaaatgccc cgatttcgcc ttttgatgga
     5581 tagatttctg cctcagcaaa aacgtctaaa atatcatcag tggtcataga caaggcgatt
     5641 tttaattttt ttagcaacac attgttgata tatttgattt ccttgctttt ttgcggcgtg
     5701 tctactatcg gcttatcttt ttgcggacca cgcgccaaga gaatcaggcc atttaggaat
     5761 gcgtcaaaaa cttggttgtt gatggttttt tcatacacat tattttctgc attatctttg
     5821 ttcttatcct gtactttggt cagtaccgcc tgagcttctt ctttagtcag tggtacaccg
     5881 cctagctcaa aagctttaat caaatccgta tctttcaaat caatcgcata acgcaatcgc
     5941 aataacctat cattgttatt catttgttcc tccgaagtat ttagtcttta ctttcttacg
     6001 tactttttgt cttgctaaga tttttaggat caatgataaa aaccgcatca cttatgataa
     6061 ggcgcccccg cattgatccg gaaggcacgg tagatttgct cgacaaggat cagacgcatc
     6121 aattgatgtg gatacgtcat ttttccaaaa gagatctgag cattgcttct tttcatgacg
     6181 gcttcgctga gtcctaaaga gccgccgata acaaaaacaa ggtggctttt tccttggata
     6241 cctaattggt cgatttgttt agcaaaagat tcacttgtag gatttttccc ttcaattgct
     6301 aaggcataga cgtattcttg ttctttgatt ttcgctaaga tccgttcccc ttctttttct
     6361 tttacttgtc tcatttgcgc ttcgcttaaa ttctccgggg ctttttcgtc aggaacttcg
     6421 atcaattcga tttttgcata ggcattcagc cgtttgacat actcattgat accttggatc
     6481 aggtattttt cttttaattt tcctactgag ataattttga tattcatgtt ttctctcctt
     6541 tggtcttcat gctcactttg tttattataa tcaatttttt cgtctatatg tttattttgg
     6601 ctatttttgt taaaaagatt tccccaacag ttatgcacaa catccacagg tttatccaca
     6661 gaaaacagtg ttattttacc ttatttcatc acattcatta ggcaaacata cgttttataa
     6721 gaatttatcc actttataca caggctgtgg atatgtttta tcccttattt ttccaatcct
     6781 atccgcgtag ttttacacag tatctgtgga aaaagaaaat caaatatttt catctgaaaa
     6841 caatgatttt tcctaaagtt tttcataaaa agttcacagt ctcaaagtag actaaagtca
     6901 acaaataaga ctatactaac agtagataaa tgaatgtaat tggaggagga acacatggat
     6961 agaaaaaatg tgacaccaaa gatgaaaaaa agtaaaaata atagcctctg gcgtaagtta
     7021 ggtctggggc ttgttggagg gatcgttgga ggactactga cagctggcat tttttatgca
     7081 gcgatgggca ctggcaacaa tagttctact gctacaagcg gcaatcagaa ttctgccggt
     7141 gaaacagttg tggaaaatat caaagtcaat gtagattctg atatcaccaa agcggtagat
     7201 aaagttcaag acgctgtcgt ttctgttatc aacttacaaa gtcaaaacca atcaagcggt
     7261 tttggcggac tattcgggca gcaagaagaa agtagcagct cagatgatag taatttggaa
     7321 gcttatagtg aaggaagcgg cgtgatctac aaaaaagacg ggaatactgc ttatgtagtc
     7381 acgaataatc acgtagtaga tggccagcaa ggtcttgaag tcttgatgaa agacggtacg
     7441 aaggtaaaag ctgaattagt tggaacagat gcttattcag atttagcggt gttgaagatc
     7501 aattcagaca aagtcgaaac agttgcctct tttggtgact caagtgctct gaaggttggt
     7561 gagcctgcga ttgcgattgg ttccccacta ggatctgaat atgcaaattc tgtcacttca
     7621 ggaatcattt cttccttgaa ccgacaagtg acaagtacga atgaatcgaa cgaaacagtc
     7681 aatatcaatg cgatccaaac agatgcagca atcaaccctg gaaattctgg tggtccttta
     7741 gttaatatcg aaggacaagt tatcggtatc aactcaagta agatcgcaag tacttctgaa
     7801 tctacttcta atgtaagcgt agaaggaatg ggatttgcta ttccaagtaa cgatgtagtg
     7861 aatatcatca atcaactgga aaaagacgga aaagtgacac gtccagctct aggtatcaca
     7921 atggtcgact tatctgccgt ttctactcag caacaagaac aaatcttgaa gattccttca
     7981 tctgtaacta acggtgtcat cgtgacaaat gtccaaacag ctacaccggc tgaaaaagct
     8041 ggattgaaac aatacgacgt cattactaag atcgatgaca aagaagtttc ttctggtgta
     8101 gaacttcaat ctgctttgta taagaaaaaa gtgggagatt ctgtcaaaat cacttactat
     8161 gaaggctcga aagaaaaaac aactactgtt gaattgacga tcgatcaatc ggcattaaaa
     8221 caaaatcaaa atagtgaaaa ttaataaa
//
LOCUS       DARPZJ010000086         7837 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.090, whole genome shotgun sequence.
ACCESSION   DARPZJ010000086 DARPZJ010000000
VERSION     DARPZJ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.090"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..813
                     /locus_tag="SLE23_002577"
     CDS             <1..813
                     /locus_tag="SLE23_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HEI8469423.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="SLE23_002578"
     CDS             807..1229
                     /locus_tag="SLE23_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469424.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2399..3367
                     /locus_tag="SLE23_002579"
     CDS             2399..3367
                     /locus_tag="SLE23_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEI8469425.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3384..3908
                     /locus_tag="SLE23_002580"
     CDS             3384..3908
                     /locus_tag="SLE23_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEI8469426.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            4284..4565
                     /locus_tag="SLE23_002581"
     CDS             4284..4565
                     /locus_tag="SLE23_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469427.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            4567..4983
                     /locus_tag="SLE23_002582"
     CDS             4567..4983
                     /locus_tag="SLE23_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469428.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            5316..5720
                     /gene="tnpA"
                     /locus_tag="SLE23_002583"
     CDS             5316..5720
                     /gene="tnpA"
                     /locus_tag="SLE23_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HEI8469429.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            5737..6885
                     /locus_tag="SLE23_002584"
     CDS             5737..6885
                     /locus_tag="SLE23_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8469430.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            7496..>7837
                     /locus_tag="SLE23_002585"
     CDS             7496..>7837
                     /locus_tag="SLE23_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HEI8469431.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2942 a         1322 c         1304 g         2269 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggt ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaaac
     1441 actttagtga gttttgtaga aagtaccttt aaaggtactt tcacattacg aacgatacgt
     1501 ccgtaggacg tactgaaagg gtgggattta tgagcgaact aatgcaaaat ttggctagca
     1561 aaaaaagtta aaaaatatat gctaataatc gagcgaaatg aacacttttt caagtgagcg
     1621 aatccgccat gacaaagctg aagcagttta tttcagcttt gtcatggcgt gtgcctagac
     1681 ttttaaaaaa gtcggcacac gagcaaatat ctttatcaag ctctaatttg cgttttaaga
     1741 cgtttgaaac gtctaagtat ataaatatat aagagtaggt ttaagagtgc ttaaatcgaa
     1801 ttttagaggg cattcagaca actttagggt tgttagggct tgccctgacc gcctgtaagg
     1861 cgctttaaga acaagataag ggatttatac taagactgtc ttaaaacgtc tcaaacgaag
     1921 gctcatagct tctcaaagag ttccttatga acatttttag caaaggagcc ggaagcgact
     1981 gcgcagtata atgtgagagc agagcgatca caccttttta agcgactgta gggagtaaga
     2041 ttcccagttg agaaaaatgc gcgaatctgt ttggagaaaa aagaagtggt tttttaggcg
     2101 ggaaattttg tccccctctt ttataatctc tttttaaacc tctttttaaa cctctttacc
     2161 gtcggctata tccttactct cccaagggaa tgacgctttt atctacatcg ttttgtctgt
     2221 ttatctacat cgttttgtct gtttatctac atcgttttgt ctgtttatct acatcgtttt
     2281 gtctgtttgt acattgaatt agtacatcga cgatgttaat ataagatgta gataaacagg
     2341 cattttgtat ttcataacgt gtatctcttg tgcgagtaag aaaggagcta ttttaaatat
     2401 gtctaatgaa atcgtaaagt atcatcatga attaaataca attccgttgc gaaaatttac
     2461 accagtcgaa atgaatttgt tcttttctat cgtatcaaga atgcgtgatg taggtgataa
     2521 aaaagtacaa tttacattcg agcaattaaa agatttaagc aattataaag caactgcaaa
     2581 tgttcgattc atagatgatt tagaaacaac gtatgacaaa ttaatggatt tacgttttgg
     2641 tagaagaagt gctgacggtt tgcaacgtga acgttttgtt ttatttaatc aatttaaaat
     2701 cgacggaaaa tctgatattc cttttgctga aatacaagtt catgaaaaag ccttaccctt
     2761 acttaataat cttgaagaat gggtgcgcta ttctctccaa caattcaatg aattagaaag
     2821 cagttattca aaaacaatgt ttcgattact aaaacaatac agaaccaaag gtttcgctta
     2881 tttttcaaaa gaagactttc atgaattact tgatattcct aaaagttaca accaaggtac
     2941 gattgatcaa cgtgtgttca atccaatacg acaagaacta accgcaatct ttaaaggttt
     3001 aacaatcaaa aagaaatacg gaaaaggacg gggaaagcct gtcattggct atcaatttac
     3061 atttaaacct gagataaaaa aatcagacga ctttaacaaa catgccccaa caaaagaaga
     3121 acaaaacaaa gcattagaac tagctaacca acaagttcaa tctgaaaaag cacctacttc
     3181 attacaagaa aaaatcaaag aacaaaagcg aaaattggaa cttttacaac agttagaaaa
     3241 gttagaaaga gaacaaaata cccaaaataa agaaaataat gcacaaaaat cagagataaa
     3301 ttccgatatt ccttcagaac taaaaaaaga cttattagac aatcttcaaa acttattcaa
     3361 agattgaggg gtttttagat tttatgacag aaaaaacaat caaagaactt gctgaagaat
     3421 taggagttag taaaacagca attaacaaaa aagtttctga cgaaaatcga aaactttggt
     3481 tttcgaaaat cggaaacaag tttgtgatta atgaaaccgg acaaaaggct ataaaatcaa
     3541 tgttttttaa cgaaaacgaa aactcaaatc aacaactagt tggcgaaaaa acgaaaaccg
     3601 aaaaccacaa aaacgccaac caagttcccg aattagaagt cctttctctc ctagaacaac
     3661 agttaaatca aaaagatatg caactacaag aaaaagacga gcaaataaaa caaatgcaaa
     3721 aattactcga ccaccaacaa caactcaccc tgcaagccaa ccaacaaatc gagaaactgc
     3781 aggaacaact acagttgact tatacggaag aatcttcgga aaataaatca acgactcttt
     3841 ctgaagaaac agaatcgata gaaaaacaat caaaggcgga gaaaaaatgg tggcaattct
     3901 ggcaataaaa ccagcaattt aaattaataa aaattgctgg ttttattctt ctttttgctt
     3961 ttgcgagcag agcaacatgg acccatgttg cgatattttg gtggcgcccc aatccccgtt
     4021 ttttcgttga atcttactcg gactgcactc gttttacagc tgatttttct gaattttgaa
     4081 agagcataag gaaacgtggt atcactttct tacgaaaggt gctagatagg ctgtgcctat
     4141 cacgtttctc agaaaaaaat ttgctatcac ttttttgcca ttgtggctag gctatgtata
     4201 gtgttttggc gaaaaatagc tatacaaata ctatatttgt atggtataca taaattatac
     4261 gctgatacga aaggaaaatt tccatggaca ttttagttcg aaatatcaat cccaaaatta
     4321 ttgcaagaat agataaacgt tgtcaggaac tcacaaccaa aacgggcaaa aaatggagtc
     4381 gaaataaata tctaaaagtt ctaatcgaaa gtgattttga ccgtcaactt atgaattaca
     4441 aaaaagatca attcgattta ttactcgaaa aatttattgc cattcaaaca gaaaatacga
     4501 acatactgaa tgactatgtt cacacaaaca accaactcat tgaaacactt atcggaggaa
     4561 tataacatga gaaaaacttc tgttcaaaaa cacgtaaccc tttatcccag tcacgttgac
     4621 gttttagatt ccatcatcga aaaaaatcca gacgtcaaca attattcaga agccattcgt
     4681 tttttatgta tgagttatga acctgatacc aatacaacca caaccagtaa ccaagcaaaa
     4741 ctcaatgcca tgggaaaaga aatttctatc atgacagaaa tcatggcaga atttgctgat
     4801 ttatatctaa aagatactgg tgttcttatc ggtacaaatt ctaaagtgta tcaagaagtg
     4861 aaagaaaaaa ttgaaaatca actcaatcct tcccgacgaa atcaacccaa aaatcgtcaa
     4921 aaagaaacca atcaaacctt tacttctgga aattttgacc caacaaactt tctaaaaaga
     4981 taaaaaaaga aaccgatccc taaaaaaatt cctcgatttc tttttaggga tcagtcttcc
     5041 agcaagattt gcaagttggt accaacttgc gaaaaaaaag aaaaatccgc ttatgcaact
     5101 tcttcttttt gtattttggg gcgctacccc aatccccaag tatcggttat ttaacagaat
     5161 taggcagaag tcgcccatcc tctataggtg ggtgatgaat gccgttcggt atgagggtta
     5221 ccgttggtaa ctcgaagacc gacaactaag gcgtattgcc tttttatttt gttccatgtt
     5281 acaatcagtc tatacaagaa atgagttgat ataacatgga attagataca aataatcatt
     5341 cagtatttct tctttattac caccttgttt tagtaacgaa atatcgtaga caagtgattg
     5401 atgatgaaat atctgattat gccaaaacta cttttgaaag aatttcagaa tcgtatcaca
     5461 ttactttagt ggagtggaat catgataaag accacgttca tattatgttc aaagctcaac
     5521 ctaaaacaga attgacaaaa ttcatcaatg cctataaaag tgccagctca agattgataa
     5581 aacgtgactt tccaagagtc aaacaatttc tttggaaaga aatgttctgg tctaaaagtt
     5641 tttgtcttct gacaactggt ggcgcaccaa ttgatgtgat taagaagtat atccaaaatc
     5701 aaggaaacaa tcataaatag aaagtaggtg aactttatgg aacaactaaa agcatacaaa
     5761 ttcagaatct atccaacaga ggaacaagaa atcttctttg ccaaatcttt tggttgtgtc
     5821 cgtaaggtct acaatctaat gcttgatgac cgaaaaaagg cgtatgaaga agttaaaaat
     5881 gattcttcta aaaaaatgac ttttccgaca ccagctaaat acaagaaaga atttccgttt
     5941 ttgaaagaaa ttgatagcct tgctttagcc aatgcccaac ttaatttaga taaagcatac
     6001 aagaattttt ttcgggataa atccgttgga tttccacgtt tcaaaagtaa gaaaaatcct
     6061 gttcagagtt atacaacgaa taatcaaaat ggtacagttg ctttgattga tagtaaattc
     6121 atcaaagttc ctaaattgaa gtcattagta agaattaagc ttcatagaca accaaaaggg
     6181 attatcaaat ccgctacaat atcacgtcat tctagcggta aatactatat ttctttgttg
     6241 tgtaaagaag aaattatcga attacctaaa actaattcca caattggtat tgacttaggt
     6301 attatggact ttgcgattct ttctgatgga caaaaaattg ataataataa attcacgtcc
     6361 aaaatggaaa agaaactaaa gcgtgaacaa cgcaaattgt ctaggcgtgc tttattggct
     6421 aaaaataaag gtaccaatct atttgaagct aaaaattatc aaaaacaaaa acgcaaagta
     6481 gctagattgc atgaaaaagt aatgaatcaa cgtactgatt ttctgaataa gttgagtaca
     6541 gaaatgatca aaaatcacga tattatctgt attgaagact taaacacaaa aggtatgttg
     6601 cgaaatcata aattagctaa aagtatttct gatgtttctt ggtcaaagtt tgtgactaaa
     6661 ttacaataca aggctgactg gtatggacga aaaatcatca aagtagataa atggtttccg
     6721 tctagtcaga tttgttcaga gtgcggacat aaagatggca agaaatctct tgaaattcga
     6781 gaatggactt gtcctgtttg tcatactcat catgatcgtg atatcaatgc tagtatcaat
     6841 attctgaccg aaggtctaag actacattct atgggattgg cttagatcca atcatcaaga
     6901 accgtaggaa ctacggggat agcttggtaa ataagagaca ccgctgttag taaagaaata
     6961 cgctatcaag tatgctctat tcccaagaag ctcccacttc aagcgttaag aaccgtcagg
     7021 tttagctaag tggtgagtag ttcactagcg cggaaatcca aagaatagga cgtaccctga
     7081 aacaaaaaaa gactgctctc acgagcagcc caaaatgaga ttatcctatt catcaacata
     7141 aaaatattac aaagtgaaga actagagaaa gacaaaaaaa gcatatcaaa tcctctcaaa
     7201 aataacaagt ctttaaaaaa tgacagataa aaatgcacaa agaactaaaa aagagaaatc
     7261 gcgtaaaatc aagcattaga agctagtaac tagctagacc aattaaaaat cacaaagtga
     7321 gcgtctctat ccattggtag aggggctact tggcatagtc gacattatgt taactaacgc
     7381 tataaataac gattatgttc ccaaaacaat attttatgaa ctataacaaa aatttgttat
     7441 cgcatattgt atattttaat tataggtgta taccacttaa atttaacaca aaggcgtgat
     7501 tattttgaaa cccaaaaaga aaatttatct aggtctcctc ttttccttga tgattggaat
     7561 ttttagtata ggaattacaa atacctatgc ttcagaaaat tctaatttca atatcaactc
     7621 ccaaccaatt gaagaacaag caattaattt tgcgaaaact gattttgaac actccataac
     7681 ttcaattctt ttaatggaaa ataacaccga aactgatatt aactatactc ttggttcgcc
     7741 atttaaaatg ctcgatggag aaaatacggc aaatagttct attttctttc cagtattttc
     7801 agacgctgat aatacgatta aatatattta taccgtc
//
LOCUS       DARPZJ010000087         7701 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.092, whole genome shotgun sequence.
ACCESSION   DARPZJ010000087 DARPZJ010000000
VERSION     DARPZJ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.092"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            198..1004
                     /locus_tag="SLE23_002586"
     CDS             198..1004
                     /locus_tag="SLE23_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469432.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1016..2236
                     /locus_tag="SLE23_002587"
     CDS             1016..2236
                     /locus_tag="SLE23_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469433.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2226..3812
                     /locus_tag="SLE23_002588"
     CDS             2226..3812
                     /locus_tag="SLE23_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEI8469434.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3851..5989
                     /locus_tag="SLE23_002589"
     CDS             3851..5989
                     /locus_tag="SLE23_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEI8469435.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(6357..7340)
                     /locus_tag="SLE23_002590"
     CDS             complement(6357..7340)
                     /locus_tag="SLE23_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEI8469436.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         2558 a         1279 c         1542 g         2322 t
ORIGIN      
        1 acgagagagg ctgtgacaac cgtcgcagcc ttttttggtt tattgcaatt gtctagcatc
       61 ttctgtaaaa tagaaacgtt agagaaaatc ttgtatcata gaaaattaag aaagaaataa
      121 gaacgcagct cggtaccaaa aatatggtaa aatggcactt gactgtaatt cactgaaaat
      181 cgcttggagg aacacaaatg tttaaagatt tgtatttatt tatgaaggac atttatcaga
      241 acagaaaatt attgctacag ttttcgatca atgacttcaa atcaagatat gcaggatcgt
      301 ttttaggaat cttatgggcg tttatcaatc cgctatttac tgtattgatt tattggctgg
      361 tatttggtgt tggactgaaa gcacaaatga tcgatgcaaa atacccattt atcgtatatt
      421 tagttaccgg gatgattccc tggttcttct tctcagatgc atttgcatca actacggttg
      481 tttttcggga atatacttat ttagtaaaga aagtcgtatt caatattcgt atcttgccca
      541 cgacgaaaat cctatccaat ctgtacaccc atttattctt cattctgatt ggcatagctg
      601 tcgcgcttat aaatggtata tatccttcag caatgtcttt acagctgatt tattatttat
      661 tttgcatgtg tgctttcttg acaggattga cttggctgac ggcatcgatc caaccatttt
      721 tacctgatat catgcaatta attacgatcg tgctgcagtt gatcatgtgg acattaccga
      781 tattatggag ccctaatcag tttgattcag gtcttgtaag catattgaaa ttaaatccgc
      841 tgtactatgt tgttcaaggt tatcgtgagt catttttaag tgaagcttgg ttctgggagc
      901 atggaacata tactttgtat ttctgggttt tcacgttagt aatgttcgta atcggctctg
      961 cagtgttccg tagattgaaa ccacattttt cagatgtgct gtaaggagaa tagctatgac
     1021 agaatatgca attagactaa aagatatcac aaaatcttat aatatgtacg caaaaccttc
     1081 ggatcgattt cgtgaagccc tcaatccttt taagaaatcc tatcatgatg tattttatgc
     1141 gttgaaaaac gtgaatgtag aaataaaaaa aggtgagatg atcggtttcg tgggagaaaa
     1201 cggatcggga aaatctacaa tgttgaaaat cattacggga gtactgacac caacatccgg
     1261 cacgatggaa atcgaaggaa aaatctcagc tttgctagaa ctaggatcag gattcaatcc
     1321 tgagtattct ggctatgaaa atatctattt aaatggaatg gttctaggat tttcaagaga
     1381 agaagtcgat gaaatggtcg atgatatcat tgaatttgct gacatcggag accatattta
     1441 tcaacctgta aaaacttatt caagcgggat gttcgttcgt ctagcttttg ctgtagcaat
     1501 caatgtgaat cccgatattt tgattgtgga tgaagcattg gcagtaggcg atcttgaatt
     1561 tcaactaaaa tgtatggaaa aatttacaga aatcaagaac tcgggaaaga cgattttatt
     1621 cgtttctcat gatatcagtt cgattcgtcg tttttgtgat cgttcctatt ggttgaaaaa
     1681 cggagaagtc gtcgaatatg gcgatacgat ggaagtaacg acgaattatg aaaacttttt
     1741 aaagaaaaaa tcagttaaaa cagtggatcg gaataaaaac caagtagaac ggttcgccgc
     1801 tccagatatc gtcgacgtga cgaaagcgga attgttggat aaagacaaaa atccggtgga
     1861 tatgctggaa caaggagaaa aactatacgt taaagtaact tatgaagtaa aagatgatac
     1921 aatcaaaaat ccggttttag gaattgcgct acgaacagtc gacaattttt atgtatgcgg
     1981 acttaatact ctactagatg gtatcaagat tccttggaaa aaaggagaga atatctttta
     2041 tctggagtat gaaaagttag gtttgttagc tggtgaatat tattttgacg ttgcggtctt
     2101 tgaagaaaat gcaacggttc ctttggtata taagacaaag tacatgaact tgtttgtcag
     2161 cggttcttat atcggagaag gcatcgtggt cttagaccat aaatgggaag aagggactca
     2221 tagcaatgaa atatgatttt gaaatggacc tagatgaaca aagcagtgtg ggaaaaattg
     2281 ccgcacagat caaaccagga agtaaagttt tagagtttgg tcccggaaac ggccgattaa
     2341 cgaaacattt aatcggagca aaacaatgtg aagtgagcat tgttgagtta gataaggaat
     2401 tgttcgattt tgtcagcgaa tttgctcaag atggatttta tggtgatatc gaaagttttg
     2461 agtgggcaaa ctattatgct ggacagacat ttgattacgt cttgtttgcg gatgttttag
     2521 aacatttggt agatcctgga aaaacattga agaaagtcag agaatttttg aatgaagaag
     2581 gagagatcct gattacattc cctaacttgg cgcataattc tgtcatgatc gatttgttca
     2641 ataaccaatt gccgtgggct tcttatggtc tcctagatga aacccataat tctttttata
     2701 ctcatgatgg cttccaaaaa gtttttgaaa aagcgggatt attcattaat attgaagatt
     2761 atttgtactt agctgtaggt gatacagaat taaaatcaac ttatgaagaa ttgccggaag
     2821 ctgtacgcta tgatttcaaa atgcgaccat ttggtgaagt ctaccaatac tttttctcat
     2881 tgatgaaaca tccagtagca caaagttcca ttgcagagcc acaaaattct aattatgtaa
     2941 aagtgttaga agtaacccag caaacgaaac aagatgaaac aatccaacaa ataccattca
     3001 ataatttcac aggggaaaat gagacactaa gtttccccgt atcagaaaca acagaaagaa
     3061 tggtgtttcg cttcgcgcaa caacctagct ttatcgaatt cagcgcagaa gctgccggag
     3121 aaaaactaac atttatcgat tcgaatgctg tagtcaaaac agtaaatgat tgttatttgt
     3181 ttgatgggaa agaattacca gagttcgttc taacggatat ttctgggaaa gaagtgacta
     3241 tccattgtca ctatcgcttt atcggggaat tgacaccaac aatgaaagaa ttgttggaaa
     3301 cgattcgtcc catggctgaa gtcacaaagc agctttctga gaaaaatgac gaattagaaa
     3361 gagaaaatca tcatcttctt gaggaaaata caagactaga ccatacgtta aaaacaacca
     3421 caaatcgcta ttgcacattg ttggaaagtg atgaatggac aataaaacat agactaggac
     3481 gacgtaagaa agaaacttcg aaaaaaatcc aagaaaaaga actttctata tgtattgacg
     3541 agaaaatctg ggatgcagaa acaaaaatat taaaaatcat cggatgggga atcgctaatt
     3601 cggatcgcca gcccttgtcc tataagttat cagctgacca atcgccattt ttcgaagcaa
     3661 ttcctgtttc acgagaagaa gtcaatcaag cagaacagct cgcaaaagga acagaagcgg
     3721 gatttgagtt acgaatcctt tgcgagcaag aacgttcatt cttagtggaa gcagtagctc
     3781 aaaatggcca atcatggatc attgaaatgt aaataatgat taacttataa agataaggag
     3841 taaacgaatc gtgcaaaaaa aagaaattgc cgtatttatc gatcaaatca ctcgtgaacg
     3901 ggccactggc gatttgctta ttgtgggctg ggcaattgat gaagtgacca aagaaatccc
     3961 tacgataaag gtagaaaaag aaaatgtgat tgctgaagca acacatgtcg taagattgga
     4021 tatcaatcat ttatataatc ttgatgttaa gacccaaagc ggttttaagg tacgtttatc
     4081 agggaaaatg agaggaaaag ccatcttaga cttccaaaca gcgagacatc aaaatggcat
     4141 agctgtgaaa ttaaacggta aataccctta tgatgacggc attgaatctt catgggaaag
     4201 aaaaaaaaga ttactgaaaa aagggataaa ttatgcaagg actcatggcg taaaaaaagc
     4261 gatccgtcgg gtcaaattgg aattgaagcc aggatcgatc gactatgcag agtggatcag
     4321 tcgtcatgag aaaccagatt tgaaagagca aaggaaagaa gcacaaggat ttgcgtaccg
     4381 tccattgatt tccatactta tgcctgtcta taacgttgaa atcaaatggc tcgaaaaatg
     4441 cattgattcg gtactggatc aaacgtatga tcattgggaa ctatgtatca gtgatgatgc
     4501 ttctactgat ccagctatcc gaaagtgtct ggaatcctat caagcaaaag atgatagaat
     4561 caaagtcgtt ttccgaaaag aaaatggaca catcagtctg gcaactaatt ctgcattgga
     4621 aatagcagaa ggagaattta tagcactctt agataatgat gatgaattac cgccatttgc
     4681 attatatgaa gtggcaaaag tgctaaacgt acatccagaa ctggatgtga tctacagtga
     4741 cgaagataaa atcgatgcag atggcaatcg ctttgatccg catttcaaag cagactggtc
     4801 gcctgataca ttgatgggaa ataattatat ctctcactta ggcgtatatc gaacaagcat
     4861 tgttaaagaa cttggcggtt tccgtaaagg ctatgaaggt tctcaagatt atgatttggt
     4921 ccttcgtgtg acagaacaaa tccctgcaga tcatatttac cacattgacc gagtcttgta
     4981 tcattggcgg acgatcccag gatcaactgc aagtaatggc gaagccaaaa gttatatcta
     5041 tgattccgga gtgaaagcat tgacagatgc cctgtctaga agaaacatca aaggaagcgt
     5101 acgtcctggc agaatttctg gattttatga gattgcttat gacgtcttgc aagaggattt
     5161 ggtcagtgtg atcattccaa cgaagaatgg ctatgaagat ctaaaaactt gtgtggattc
     5221 gatcatcgaa aaaacgtctt attcaaatta tgaaatcatt attgcggata acggaagtac
     5281 agatccaaaa atgcaagaat tatttgcaga atacaagcat cagctgaaag accgctttat
     5341 cgtagaattg attgacattc cattcaatta ttctcgaatt aacaatttag cagcagaaaa
     5401 agcaaacggc aaatactttt tattcttgaa taacgataca gaagtgattg agccagattg
     5461 gatgacggtg atggtttctt atgcacagtt tgatcgaatc ggctgtgtag gagcaaaact
     5521 gttttatcca gatgatacaa cgcagcatgc aggagtatta ttaggaatcg gtggtgttgc
     5581 agggcatgca ttgaataact atgatcgaac acattgtggt tatttcggcc gattggtcat
     5641 tgacgtcaat tacttagcag tcactgcagc ttgtatgatg gtcaaggcag ctgacttcaa
     5701 tgctgttaac gggtttgatg aaacattaga agtagcattc aacgatgttg acttgtgctt
     5761 gaaagtttat gaactgggtc gttacaatgt ctatgcacat caagcagaat tgtaccattt
     5821 cgaatctaaa tcaagaggtt atgaagatac tccagaaaaa caaagacgtt ttgctggtga
     5881 aatcaaaaaa atgcaagata aatggccagc atatattgcg catgatccat tttacaatga
     5941 taatttaaca aaagaaggaa tcggcgactt ttcgttgaga ccagattaaa ctataataaa
     6001 aagctgttat gttgtgattc gctcgcacat aacggctttt tatagttttt tgtcaaaaaa
     6061 aggcagaagg tgccgactca aaaaaataag tcgaggttgg gacagaagtg tttaactccg
     6121 agaaataaga agaaattcac gaaaattgct tttcaaattt ttgtgaattt cggcttattt
     6181 aagaagaagt tgcttctgct cccaccgttt attcgttttt aaagaatgag acaaaagtgt
     6241 ttcttacttt tgtcccacgc tcttattcat gctcagagcg ccaatagata caaaatcata
     6301 gccaaagttt cacgaaccct agctgtcaaa gaatcgatat tttattttaa tataggctat
     6361 tttaaaataa atggtttaag gtattcctct acaaaagcca ctctatcaat tatcatgggt
     6421 ttaaaataag aagtgatgga gataaccaga ttgttcttag cgtcaatata aagaacattt
     6481 ccactattac caattgctga atatatttcg ttctcagaat ctaataccca ccataaatag
     6541 ccatatctca tattttgtaa gtcttctaaa gcactggttc taggtttgaa catctcgttt
     6601 atccacatgg gtggtacgat ttgttttcct ttatacatcc ctttatttag gcataataca
     6661 ccaatttttg ccagatcact tgccgataaa cacaaaccat atcctgccgt cccgatattt
     6721 agtggatcac aaaaccagac attggtttta ggagacttat ccattgtaaa ctgcttatgt
     6781 tcttcagctg tttcagcata ataattgaca tggtttggta tccctatagg atcaaataga
     6841 tacttattgg caaaatcaac agttgttagc ttacttgtct gatacaacaa gccagttaat
     6901 atgtgtaaac agacagtttg atagttgaat tcgccggtta taccttttct tcctcccaat
     6961 aaatctagtg atgtttttgt ccaatcttca cttgaacaga cttttgtcca tggatcgcct
     7021 ttacatttgt agggtgcttt cattgttagc aagtgcttga ttgtaatagc gtaaatagtt
     7081 ttctccccgc gtttcacttt atactctgga aaataatcta atactttatc atcgatactt
     7141 ttgattaatc cttgctctaa agcaatgcca atcagcaaag atacaatact tttcgttgct
     7201 gacatgatat gacaagtatc gtctttttta taaccattcc attcatctgt ataaacttct
     7261 accccatcct tatatgcgac aatttgacat atatttggtt gtcgaaaacc aataaaatca
     7321 tgcaactctt gtttattcat aagatattac ctcactttct tctataagca taatgtcatt
     7381 aaaaatcgat ttcaattttt tcgattcttc acgtaataca ggtattctta tggactagac
     7441 agcgctttgg gaagatggat tctctgaaaa atataaaggt tcactttatg agtggataaa
     7501 aaaagcagca aatacttcga cttctttaat ttaccaacat tagtgaaaat cgattcatct
     7561 ggagatttgt aatttagagt ccttgtcttg attagaggtg tataaagctt tttattagac
     7621 atttttaaat tccattacaa tttgcttata aactaggttt ttaaaggtga ctatggtaag
     7681 ataatagaga tattattttg t
//
LOCUS       DARPZJ010000088         7699 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.093, whole genome shotgun sequence.
ACCESSION   DARPZJ010000088 DARPZJ010000000
VERSION     DARPZJ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.093"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            544..1107
                     /locus_tag="SLE23_002591"
     CDS             544..1107
                     /locus_tag="SLE23_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8469437.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="SLE23_002592"
     CDS             complement(1386..1673)
                     /locus_tag="SLE23_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8469438.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="SLE23_002593"
     CDS             complement(1663..1992)
                     /locus_tag="SLE23_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8469439.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="SLE23_002594"
     CDS             2297..2626
                     /locus_tag="SLE23_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8469440.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="SLE23_002595"
     CDS             complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="SLE23_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEI8469441.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="SLE23_002596"
     CDS             complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="SLE23_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEI8469442.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4890..5498)
                     /locus_tag="SLE23_002597"
     CDS             complement(4890..5498)
                     /locus_tag="SLE23_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEI8469443.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="SLE23_002598"
     CDS             complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="SLE23_002598"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEI8469444.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6528..7496)
                     /locus_tag="SLE23_002599"
     CDS             complement(6528..7496)
                     /locus_tag="SLE23_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEI8469445.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2352 a         1532 c         1280 g         2535 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ataggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tagttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatatttcta gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc
     4561 cccgtaaatt acagtcaatt atttcgccct actggattta ctattatcac caatgtagat
     4621 gaattttcat aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
     4681 ggcggtgtga aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca
     4741 gcgcacgcag ataatgaccg caatatcgct ctgccttaca tcttcaatac tatctactat
     4801 atataaattc cctaagaacc agttacatac gtcgggtttc ctgccgaaag agttagctta
     4861 tatagtttgt ccgtgcaacg gttaaaagtt tatttaacgg ggaaatcaaa atagctattg
     4921 gggtatggtt cgtctcttaa tacatagtgc caccattcga ggctatatgc ttcaaaccca
     4981 ctgttttcca tgatggagcg caaacgtctg cgattttgcg cttcattgca tgatattcca
     5041 tttgccgcat gatgagagcg ttcatccata aaatcaaatc ggctccccat tggtacaagc
     5101 tcacccgtgt ctaatcgata aagcgtaaga tcaatggcac tgccgcggct atggcttgat
     5161 tttgaagcca cgtatccttt tgaaatcatc tcagttcggt caatattggg ataataactt
     5221 tcctttgtca ggttattttc cggctgtgca gcccattgca taaaacagtt tacagcacga
     5281 ttaggacggt aaccgtccca tagaagcaat ccgtaccctt gggtagcagc cagttctttt
     5341 gccttcaaaa gcgattcagc caactcgtat gtccctacaa tgcgatttac ttcataaccg
     5401 tcaaccggtt ttccggtgaa attatcccaa gtggcatatt tagcgtccca acgaacaccg
     5461 tgtactattt catctaaaaa agtaaatcct atttccatgc ttatcacccc tttaacgcta
     5521 atacgatcaa gcggtcaatc agttcgggaa gtgcaatacc tgcagcggcc atcatacggg
     5581 gataacgact gtatgacgtg aaaccgggca gagtattgac ttcgttcagt acaatgcggc
     5641 cgttatcttg taaaaacata tccacacggg ctagacctct acagccgagc gctttatata
     5701 ttttttttgc cgtttcctgt atccgtcctc gctcctctgc tgaaaggtct gcgggaacgg
     5761 ttataactgc gttttcagag cctttttccg gctcgacttc ctgatgaata cgaaagattc
     5821 cgtactgcag cctgatttgg tccacctcgc caacagctaa cgcggcactg tttcccaata
     5881 ccgcacaacc gacctcacag cccgaaacag cctgctcaat taagattttg ctgtcatatt
     5941 gtcttgccga ttcaattgcg tagtccaatt cgtccgcgct attgactttt ttcacaccga
     6001 aggatgagcc tgaacgcgcc ggcttaacaa aaacaggata ggtaaacgta gctgccaccg
     6061 gcctatcatc tttattaata acccaaaagg cgggagtagc tatcccagca tttttcgcaa
     6121 cgatgtatgt caacgatttg tccatacaaa ttgctgagct ttgaatatcg cagcctacaa
     6181 aagggatacc ggacaattca aacagacctt gtatggatcc atcttcacct gacttgccat
     6241 gcaaagctga aaatgctaca tcaacatggt tgatttcata ttcatggttc tttttaacaa
     6301 gtaatccgtg cattttttta tccggcgaga gtacagctga atagcaattg tcgttttccc
     6361 attccgcgca aggtttttcg cacattttcc atacaccaga tttcgtaatt ccaatgtata
     6421 acggctcgta tttttcttta ttaatgttag cggctatctc tattgcagat tttaccgata
     6481 cgtcatgctc ctctgagcaa cccccaaaca gtattgcaac ttttattcta ttcatgctcc
     6541 tgtctccttt caaaatccaa acagttttta atggtttttt caacggtatc acgcaacgct
     6601 tgctcggtat aataggccgt atgcggtgtg attatcacgt taggcattct ttgaagttta
     6661 agtaaaaatt gattatcaat tggtttttgg gtgcaatcag agtagaaaaa ctcttcctct
     6721 ccttccaata catccaatgc ggcaccgccc agtttcccgt tttctaatgc tttaaccaac
     6781 tcataggtat ctacaagtgg accgcgccca gtattgataa gaaatgctcc ttgcttcatt
     6841 ctctgtattt gttcgtggct gataatatag tgcgtatccg tattgagcgg cacatgaagc
     6901 gtaacgatat cgctattttg cagcaactca tcaaacggta catagtttac ctctatactt
     6961 cggctgcgac tataagccaa cactttacat ccaaatcctc gcagccgctc aataaccgct
     7021 ttgcctatct ggcccgttcc caccacacca actgtcatgt cgctgagtac cttgccacgg
     7081 tcgctgtcca acctgaaatc atgtttttcc acagagcgca caatcgattt tacgttgcgt
     7141 actgccataa gaattagcat catagtataa tcggcaacgc tatccggcga gtacgccaca
     7201 ttgtcgacag tgatgcccat tctcttagca gcagttgtat ctatatgatt gcagccgatg
     7261 cttcgggtag aaatatattt cacaccggct ctcttcagcg caagaagaat agaggcggaa
     7321 atctctgatt tatgtcccac actgatacat tgattgaaag gcgcggattt ggcgttggat
     7381 tccgacacgt tggcgttaat tatcgttgcc ataacgccaa agcgaggcga aagagcatgg
     7441 aatgcatctg cctcatcctg ctcacatcca taaacagtaa tgccgatgtt attcataatt
     7501 aagaccaacc ctttctgtga aaggcaccaa ataaaacggg gatgccaatg gtaatcttgt
     7561 caaatctttc tctgaagaac gaaaacggct cgttcttacg gtattaagtc taccgtgtaa
     7621 gaacgagccg tttcttaata ttaaattgtt aatttcctaa gaaaaagtaa agataacctt
     7681 gagattttcc taaaaaatt
//
LOCUS       DARPZJ010000089         7625 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.094, whole genome shotgun sequence.
ACCESSION   DARPZJ010000089 DARPZJ010000000
VERSION     DARPZJ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.094"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(14..706)
                     /locus_tag="SLE23_002600"
     CDS             complement(14..706)
                     /locus_tag="SLE23_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEI8469446.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="SLE23_002601"
     CDS             complement(1143..1712)
                     /locus_tag="SLE23_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEI8469447.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="SLE23_002602"
     CDS             complement(1786..2109)
                     /locus_tag="SLE23_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469448.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="SLE23_002603"
     CDS             complement(2263..3075)
                     /locus_tag="SLE23_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469449.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="SLE23_002604"
     CDS             3429..4277
                     /locus_tag="SLE23_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HEI8469450.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="SLE23_002605"
     CDS             4422..5363
                     /locus_tag="SLE23_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HEI8469451.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="SLE23_002606"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="SLE23_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1371 g         2470 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacct
//
LOCUS       DARPZJ010000090         7596 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.095, whole genome shotgun sequence.
ACCESSION   DARPZJ010000090 DARPZJ010000000
VERSION     DARPZJ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.095"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(940..1353)
                     /locus_tag="SLE23_002607"
     CDS             complement(940..1353)
                     /locus_tag="SLE23_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HEI8469452.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="SLE23_002608"
     CDS             complement(1809..2294)
                     /locus_tag="SLE23_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469453.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2678)
                     /locus_tag="SLE23_002609"
     CDS             complement(2433..2678)
                     /locus_tag="SLE23_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HEI8469454.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2871..3671
                     /locus_tag="SLE23_002610"
     CDS             2871..3671
                     /locus_tag="SLE23_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8469455.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3690..5558
                     /locus_tag="SLE23_002611"
     CDS             3690..5558
                     /locus_tag="SLE23_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEI8469456.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNAVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5551..6042
                     /locus_tag="SLE23_002612"
     CDS             5551..6042
                     /locus_tag="SLE23_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HEI8469457.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6030..6584
                     /gene="srlA"
                     /locus_tag="SLE23_002613"
     CDS             6030..6584
                     /gene="srlA"
                     /locus_tag="SLE23_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEI8469458.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6602..>7596
                     /locus_tag="SLE23_002614"
     CDS             6602..>7596
                     /locus_tag="SLE23_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEI8469459.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2706 a         1215 c         1442 g         2233 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaag
     2641 ttttcattag aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca
     2701 ttgcttatat aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg
     2761 ctcttccatt agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt
     2821 agtgagcttt tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt
     2881 ggttggatat tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa
     2941 gtatcgtcga aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat
     3001 gccgtataca gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca
     3061 tagaagaagg gatatataaa gtaatgaaac atttcaagac gatcgatggt ctagtcaata
     3121 atgcaggaat aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg
     3181 aattatcaga acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga
     3241 tgagccaagc agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatcttt
     3301 cttctgaatc aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag
     3361 cgatgaacag ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg
     3421 taggtgttgc accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag
     3481 ctctttctta tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa
     3541 gtacgatccc tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt
     3601 atctttcaga aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa
     3661 caagaggata aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat
     3721 tgaaattact agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa
     3781 ccagtaatca aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg
     3841 caaaaatcat ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg
     3901 atgagatcat gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa
     3961 tcgcttattt actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt
     4021 ctgaagaagt cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga
     4081 tgatcaatga ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag
     4141 gagatgagct agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga
     4201 cgaaaacaga acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga
     4261 atgctagtaa acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa
     4321 tctctagtaa ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata
     4381 tccaagaatt caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc
     4441 aatatgaaaa agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga
     4501 taaggaaagc taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac
     4561 gattagatct cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct
     4621 ctttattgat aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga
     4681 tagaaaaaaa gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag
     4741 ctatcttgca acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt
     4801 tagcatttcg atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga
     4861 caggaaaagg aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata
     4921 tacaaataac acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg
     4981 ctgtttttac aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttga
     5041 ctaatctttt tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat
     5101 tagccgggtt tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc
     5161 aagaatattt aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat
     5221 ttgaaaaaag gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg
     5281 cttttcctca cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa
     5341 ctgatcaagg tttagcagaa acaggaggaa atgcagttat ttttttattt gccatacctg
     5401 aagaaatgac ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac
     5461 tcataaaaat gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa
     5521 aactaatcaa aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc
     5581 gcagcttcag cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat
     5641 caaacatata gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa
     5701 atccgttcag gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc
     5761 agaaaaatgc aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt
     5821 gaagatatcc attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca
     5881 caagcagctt tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa
     5941 agtgaacaac cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt
     6001 acgatcaaag aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat
     6061 ttatgaggct gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac
     6121 cagttgtctt gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc
     6181 gagtaacgaa agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac
     6241 cgttcttatc tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc
     6301 cagaatacta caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg
     6361 gtgtattccc ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga
     6421 tcgaaacctt agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc
     6481 tgatgaactt tattggtggt tggataactg attttactac tggatttgta tgcagacagc
     6541 aaggaatcgt tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta
     6601 aatgtatggt gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat
     6661 taggccgaca aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat
     6721 gatcgtagat aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc
     6781 aatacctgat agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg
     6841 aatttatcct aaaaaaggga taccaaccat caatatcgtt cccacaggaa aaagtggccc
     6901 attagcacaa tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca
     6961 gccactaatg gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa
     7021 gtacaaatat gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat
     7081 agcaaaaatt ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga
     7141 agcagtagat acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat
     7201 tggtgtgata caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc
     7261 aggaaatgca gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc
     7321 tttgcttggt ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat
     7381 tgggaaagga aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca
     7441 aaatgcatgt gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt
     7501 agaagtaggt gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat
     7561 cattgcttgg gtagcaagtt ttggattata tagctg
//
LOCUS       DARPZJ010000091         6962 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.096, whole genome shotgun sequence.
ACCESSION   DARPZJ010000091 DARPZJ010000000
VERSION     DARPZJ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.096"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..193
                     /locus_tag="SLE23_002615"
     CDS             <1..193
                     /locus_tag="SLE23_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469460.1"
                     /translation="GRMSELGYSMMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPL
                     VPKGYDFLDSISKLEKMND"
     gene            271..945
                     /locus_tag="SLE23_002616"
     CDS             271..945
                     /locus_tag="SLE23_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEI8469461.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            938..1102
                     /locus_tag="SLE23_002617"
     CDS             938..1102
                     /locus_tag="SLE23_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469462.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            1178..2320
                     /gene="dcm"
                     /locus_tag="SLE23_002618"
                     /pseudo
     CDS             1178..2320
                     /gene="dcm"
                     /locus_tag="SLE23_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            2310..2600
                     /locus_tag="SLE23_002619"
     CDS             2310..2600
                     /locus_tag="SLE23_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469463.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            2859..4043
                     /locus_tag="SLE23_002620"
     CDS             2859..4043
                     /locus_tag="SLE23_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8469464.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            4040..4177
                     /locus_tag="SLE23_002621"
     CDS             4040..4177
                     /locus_tag="SLE23_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HEI8469465.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            4923..6833
                     /gene="ltrA"
                     /locus_tag="SLE23_002622"
     CDS             4923..6833
                     /gene="ltrA"
                     /locus_tag="SLE23_002622"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEI8469466.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         2437 a         1118 c         1539 g         1868 t
ORIGIN      
        1 gggtcgtatg agtgaactcg gatattccat gatgtttggg gaggtcgaaa aaaacttctt
       61 tatgaagcac atcaaaggtc gaggttatgt ggatacaggt ggcagtgtga ttagtgagtt
      121 ttatacgcca cttgtaccaa aagggtatga tttcttagat tcaattagta aattagaaaa
      181 gatgaatgat tgagtgatct tcaatactga ctttatactt caagtaacgt ataatacttt
      241 tatatagtag gaagaaaggg gataattaat atggaaagta atgattctta tttagagtat
      301 gcaaaagcaa ataaggataa gtttatttct tatattatca aagggaaatc ccccgaagtt
      361 ggacgagacg cagtttttat ggcagggagt cctggggctg gaaaatcaga ggttgccatt
      421 ggattagctg agaattatga taaccatgtg attattgatg cggattactt tcgcacccag
      481 tttcctgatt ataatggaaa aaactctagt ctctttcaaa aagcatcttc ttggttggta
      541 gagcaggcat ttagatatgt cttagatcat ggctattctt ttattctgga tgcaactttt
      601 gcaatattaa gtgctgaaaa aaatatctcg cgggcgttga aaaaacattt tcgagtgacg
      661 attttctatg tttatcaaga ccctaaaatc gcttggaaat ttacacaaga acgtgaaatt
      721 gcagagggac gtcatgtgcc gaaaaaggca tttattaacg cttttttcaa atcaagagag
      781 aacattgcaa aagtaaagag taaacatcca gatgtattgc ttcatatcat aataaaagat
      841 tatacgaata atatttccga agttcattat gctacggata atctagaatt atttttacca
      901 ctagggtata gtaggaaaga tttggaggtt caattacatg actgagaaag aacaagtaac
      961 gaaaattgta aagaaataca ataagagcat tgcggattta tcggaaaatg ctactgcaaa
     1021 agagttcaaa acggtgatta aatatgtagc cgatcaggcc aatgaaaaac aacggaaatt
     1081 agttggatta aataaaaaat agtaggacaa attaataatg tatgagccaa gagcaaaatg
     1141 ttcttggctt ttttctttgc aatgaatgag gtaatgtatg agatttttag atttattcgc
     1201 cggtattggt ggctttcgtt taggtatgga acaggcgagc catcattgta tcggtttttg
     1261 tgaaattgat aaatttgcta gacgtagtta taaagcaatt catgatacaa gtaaggaggt
     1321 ggaaatgcat gacatcacaa gtgtatcaga tgagtttatt caatccctcg gaccagtgga
     1381 catcctttgc ggcggatttc cgtgccaagc tttttcaatt gcgggaaagc ggcaaagatt
     1441 ttccgatact cgaggtactt tattctttga aatcgctcgg ttcaccactc ttctccgacc
     1501 taagctttta ttccttgaga acgtccgagg attgctcaat cacgaaggag gggctacgtt
     1561 cgagacgatc ctccgaacgc tggatggatt ggggtatgac gtggagtggt aggtgcttaa
     1621 ctcaaaggcc tacattcccc aaagccggga gcggatattc cttatcggac attctcgaga
     1681 cgcatgtacc gaacaagtat ttcctatcat tggaccgtct tcaacatctg atcaaaacat
     1741 cagaaatttg gtaaatatca atccttccaa tcgaggaatg ggtggacaag tctatggttc
     1801 agatggcgta gcgccaacct taacaggtga tgaaggaatc aaaatcgcac tgccagcaag
     1861 ggatggaatc tctgtagcag gactattacc gggaaagttt gaacaaggta atcgagttta
     1921 tgaagttact ggaaccgccc ccaccttgtc aacgaaacaa ggtggtacaa aaatcatgat
     1981 tcgaaaaaat gaaacagaat atcaagaggt gaagccagaa gacagtgtga atctggcttt
     2041 tcctaattcc acaagtcgcc gaggtcgtct gggaaaacag agtgttcata ccttactaac
     2101 aggagaccaa caagcgatcg tcacggatca gtatcaaatt cggaagctaa cacctagaga
     2161 gtgttggcga cttcagggct ttcccgattg ggcttttgat cgagattctc aagtcaattc
     2221 agatagtcag ttgtataagc aagccggaaa ctctgtaaca gttccggtca tttttgatat
     2281 tgccagaaga ttaaaagagt tggatgtaca tggtttatga tgagttgatt ggagaaattt
     2341 attgggtgat tggaaagatt cagtcagacc cagaattaga agaacaattg cgacggttaa
     2401 aatttgatat tcgcaagaat ggtgtcaaag tcgctggcga tccatattta atgaatgagg
     2461 agacggatgc tcgaattgaa ataaatcaag taattgcaga atttgagcgg attgcggacc
     2521 aagcaaaaga accagatatt cgtcaatact tgttagaaat gaaagcagag ttggaagtaa
     2581 atggtattac agatgagtaa cctaaaccaa cacaactgac tgttaggcgc tgaccgcgga
     2641 ggattcgcga agcagaaatc ctccgtggtg ctgtgcctgt tcatggacgg cgttagccga
     2701 ccatgatgtc tcacccccgt atctaacagg ggggtacaaa aacacaaaaa ataagtaagc
     2761 aaccattaag aatgcttgtt gtatcaaaga tagtaagtaa tttgtatagg tgttaactca
     2821 tttgaaaaag ttaacacctt gaatttggag gtgagaactt ggcacaacgg aatttagatt
     2881 atcggctatt aaaagaccga cgcaacgaat acggcgtttc acaaaataaa ttggctacgg
     2941 cttgtggact tagtcggccg tacttaaatc agatagaaaa tggtggcgta accgcatcta
     3001 taaaaaccat gaggaaaatt tttgaccaac tggaaagctt taatcccgat ttgcctttga
     3061 cgttactgtt tgactatgta aggattcgct ttcccacaac ggatgcacga aaaattattc
     3121 aagaaattct ccatttgaaa tttgagtata tgctccatga agattatgcc ttttactcct
     3181 atcaagaaca gtatgtcatg ggtgatattg tggtgatgtt gtctcatgaa gaagataaag
     3241 gtgtgctttt agaattaaag gggcgaggtt gccgacaatt tgaaactttt ttactcgctc
     3301 aaaagcgtag ctggtacgac tttttcgagg attgtctaaa ggccggtggc gtgatgaaac
     3361 gcttggactt ggcaatcaat gatcgagtgg ggctattgga tatacctgag ctaacgaaaa
     3421 aatgtcagaa ggaagaatgt atctccttgt ttcgtacctt taaaagttat cgttccgggg
     3481 aacttttaaa ggctgatgaa aaggacggca tgggcaatac cttatatatc ggcagtctca
     3541 agagtgaggt ttatttctgt ttgtatgaaa aagactatga acaatatatc aagttaggga
     3601 ttccattaga ccaaactgag acgaaaaatc gttttgagat tcgactgaaa aatgaccgtg
     3661 cttttcatgc gattcaagat ttgttaaaag gtcgtagcat tgagagcacc acgttttcca
     3721 ttatcaatcg ttacttgcga tttgcggata aagtagaagg taaaaggcga accaactggc
     3781 ccttgaatga acaatggggg cgttttattg gacggaatcg gaaagagatt caattaactt
     3841 ccgagccaaa accgtatacc attgaacgaa ccttgaattg gctaggccga caagtcgccc
     3901 ctacgtggaa aatggctaag gagttggatc gattgaatcg gacaacctat atccaggata
     3961 tggtacagaa tgcacgctta tcagaccgac ataaaaagat tttggagcaa caaagtatgg
     4021 caattgaaaa tttgattata tgaaaagagg aatcgtcatg ggaattgtaa aagatatttt
     4081 tttggtattt ggtggcagta tgcttggtgt tactgtgatg tgcttgatga atgcaagtgc
     4141 agcagcggat cgagcaatgg aaaagaaagg aaagtgacaa gatgaatttc ggacaaaatt
     4201 tatgtgcgac tcgttcctta gtgaaaagct aaggcactaa taaaagaacg aaaaagtttg
     4261 gttattagga gaactgataa tctgacaggt ggaatgatga agtaacgctc tgaaacgcct
     4321 gccctgagcc tccgacaagc attgtatgag gaaactcaga atgtttgaag ctcggtaaag
     4381 acggctgaaa gataccgtaa tagttgatga acatatatct tctatcgaaa actatccaga
     4441 ggtgggtagc gtatccaaca ggtcgggggt ctataaaata tctatggtta gaatgttcta
     4501 taaggaactg acgaaacagc gaatgtacgg gtctaaattt gaactttgta gaaatgcaaa
     4561 ggtacgagaa atcgtagctg gtgtggcaaa gtaagaatat aggttatgaa atgccatata
     4621 acgttacagg cggtatcaag ccagcaggct tatagctagt gacctaagga tatatatgta
     4681 tagataagat tatcggaacg aggaaaggta ttgggttctc atcaagagaa taaactgacg
     4741 aagaacaata agcagttgaa ctaatgctga aaagcagagg gcgaacctaa gaaattcttg
     4801 taatgagaat ggaggaatgc cctcaagtcg tgtatatatt agaaaagtat tatgttgttt
     4861 caataaggat tacgagtaag ataaaaaagc tcactcaatt tcaagtaaag gagtgaagcc
     4921 ttatgcctaa aaataaaaat gaaacattgt gtgtagaaga tttaagacac gctgaatatt
     4981 acgaaatgca aaacaccttt gatgatttat atgccaaaag taagaatgga gatattttca
     5041 ctcatcttat ggatattatc ctatcgagag aaaatatatt actggcatat cgaaatatca
     5101 aagcaaatgc aggcagtaaa acagcaggaa cagacggtac aataattaaa gatattggca
     5161 aattgccagc agaaacagtt gtcaaaaaag taagatacat tgttgcaggc agtccacatg
     5221 ggtatcgacc taagccagtg aggcgaaaag aaataccaaa accaaatggt aaaaccagac
     5281 ctctaggtat tccttgtatg tgggacaggc ttatacaaca atgtataaaa caagtattag
     5341 aaccaatctg cgaagctaaa tttagtgaaa acagctatgg ttttagacct aataggtcag
     5401 ttgaaaatgc aataaaagca acctataacc gcctacaaat cagccagcta cattatgtga
     5461 ttgaatttga tattaagggt ttctttgaca acgtgaacca ttccaagctg ataaaacaga
     5521 tatgggctat gggaatacgg gacaagcact tgatattcat tttaaaaagg atattaaaag
     5581 ctccaatcaa aatgactaac ggtacaataa catatccaga gaaaggaact ccgcaagggg
     5641 gaataatatc cccactacta gcaaacattg ttcttaatga gttagaccat tgggtagaaa
     5701 gccaatggca ggaaaatcct gttacaaaaa actatgtggt tcatatcaat aaaagcggta
     5761 gcccatgtaa aagcaacgct tacaaagaaa tgaagaaaac aaagttaaag gaaatgtata
     5821 tggttcgtta tgcagatgat tttagagttt tctgccgcta caaggaaagt gctgaaaaag
     5881 ccaaaatagc aatcactcaa tggattgaac aacgattaaa attggaagta tcacaagaaa
     5941 aaacaagaat tgtaaatgtt agaaaaagat actccgactt tcttggtttc aagattaaaa
     6001 tgataccgag aagaaagaag ttagttgtta aatcacatat aagtgataaa caattcaaaa
     6061 accaaaaaga caagctggta tcacaggcaa agaaaattgc ttctccctca aaagggaaaa
     6121 cggaattaga agaaacaaga ctttataatt caatggtatt aggtatgcaa aattattatc
     6181 agattgcaac gaatgtaaat ctggattgta tgaaactgaa tagagctgta atggctatct
     6241 tcactaacag attaggtaca aacaaaaggg gcagattgag aaaaacaggc agacaactta
     6301 cgacaaagga ggcaacaaga tatggtaaat ctaaaatgct tcggtatgtt gctggcgagg
     6361 gcgaacctat tttccctgtt ggatatatcc aacacagaaa accaatggca aaggtgtatt
     6421 tagcgaattg ctacactcta gagggaagaa aatttatcca caccaatcta agtgttgata
     6481 aattactgat gtaccagtta atgaaattat ctttggaaaa tcgcacaata gaatacgcag
     6541 acaatcgaat ttcgctattt tctgctcaac atggaaaatg tgctataact ctggaagaat
     6601 ttcaacaagc taatgaaata cattgtcatc atattgtacc aactggagct ggtggaaatg
     6661 acgattataa aaatcttatt ttggtaaaag aggcggtaca ccgtctaata cacgctaaaa
     6721 cagaagaaac aatacaaaaa tatatagctc tattgaagct aaataaagtc cagctcataa
     6781 gactaaataa atatagagta ttagctggca atcaagaatt aaacttgata taggtctact
     6841 acataaatac ttttcaatat aaacacgatg gaacgcggag tgcggtgaaa gtcgcacgct
     6901 ccgtgtgaat ggggggaaaa gtttgagata tttataatat caggaactta cctatccata
     6961 ta
//
LOCUS       DARPZJ010000092         6901 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.097, whole genome shotgun sequence.
ACCESSION   DARPZJ010000092 DARPZJ010000000
VERSION     DARPZJ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.097"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            1..345
                     /locus_tag="SLE23_002623"
                     /pseudo
     CDS             1..345
                     /locus_tag="SLE23_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
     gene            361..510
                     /locus_tag="SLE23_002624"
     CDS             361..510
                     /locus_tag="SLE23_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469467.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            591..1187
                     /locus_tag="SLE23_002625"
     CDS             591..1187
                     /locus_tag="SLE23_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEI8469468.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPEKTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            1200..2099
                     /locus_tag="SLE23_002626"
     CDS             1200..2099
                     /locus_tag="SLE23_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEI8469469.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            2102..2233
                     /gene="ssb"
                     /locus_tag="SLE23_002627"
     CDS             2102..2233
                     /gene="ssb"
                     /locus_tag="SLE23_002627"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8469470.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            2255..2587
                     /gene="ssb"
                     /locus_tag="SLE23_002628"
     CDS             2255..2587
                     /gene="ssb"
                     /locus_tag="SLE23_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8469471.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            2632..2865
                     /locus_tag="SLE23_002629"
     CDS             2632..2865
                     /locus_tag="SLE23_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469472.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(3024..3146)
                     /locus_tag="SLE23_002630"
     CDS             complement(3024..3146)
                     /locus_tag="SLE23_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEI8469473.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            3336..3560
                     /locus_tag="SLE23_002631"
     CDS             3336..3560
                     /locus_tag="SLE23_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469474.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            4003..4209
                     /locus_tag="SLE23_002632"
     CDS             4003..4209
                     /locus_tag="SLE23_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEI8469475.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            4209..4460
                     /locus_tag="SLE23_002633"
     CDS             4209..4460
                     /locus_tag="SLE23_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469476.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            4476..4631
                     /locus_tag="SLE23_002634"
     CDS             4476..4631
                     /locus_tag="SLE23_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469477.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            4641..4913
                     /locus_tag="SLE23_002635"
     CDS             4641..4913
                     /locus_tag="SLE23_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469478.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            5358..5537
                     /locus_tag="SLE23_002636"
     CDS             5358..5537
                     /locus_tag="SLE23_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469479.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            5596..5952
                     /locus_tag="SLE23_002637"
     CDS             5596..5952
                     /locus_tag="SLE23_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469480.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         2469 a         1114 c         1369 g         1949 t
ORIGIN      
        1 ccacttttct agccaatatc caaaaatttg tctctcactt attggaagtc gtaccagggc
       61 aaatccaatc cactgatttt ggatcgacgt tacaagaagt gaaagcagcc agtgaaaagc
      121 aagaagccgc gcgtcattta ggaatttgtc caaaatgcca ggaacaagaa gtcttactct
      181 atcaaaaggt ggcagcttgt acgtctgaag cctgtgattt taaaaggtca gaagggttca
      241 tttgaagcaa cgattgtttt aaaagaagac ttcactacag gctttgaatt ttctgaaaag
      301 aaaaaaacga acttcaagaa aagaacacgc cgcactgcaa aataatggag ggttaatctt
      361 atgcgtaata ccacacacaa acaacaagaa atcgaaaatc aaaaagccaa aattcgttca
      421 gaacaggaaa aaatgcgtgc cagcaaacga agactgcagc aattgaagaa ccagcagagg
      481 attcaaaaag aaatcgaatt agatcgataa aatcttccta actattgtat acgtataaac
      541 ttatgttata ctgtttttat aagtttatac gtatacaaag gagggagaaa atgacaaaag
      601 caatggtata caagctgcta gaagaattta atggaacttt ggctttgaag gatgccaaaa
      661 aagcgggcat ttctcctgta acgatcaaac gtatggtaga tcgaggggag ctggatcgag
      721 agtatccagg ttttttcacc ttacctggtc aatttcctga tgaattgttt atggcgcaaa
      781 aaaaatatga acgcggcatt atttcacata ttaccgcgtt agatttgtat gatttaacag
      841 atatgatccc tagacagatc gatctgactg taccttacgg ttatcacgtt tctgaaaaag
      901 gattgaagga attcgcagtt gagctacact atacaaaagc ggaatggtat gaattaggta
      961 agattgaaat aaaaagtcgc tatgggaatc ctattatagc ttatgatcca gaaaaaacct
     1021 tgtgtgacat ttggaatccc tggtataacg ttgaggatga aatcaaagta aaagcaatca
     1081 aaaactacat ggagtcggac agaaaaaatc ttagaaaatt gaatgagtat cgacgaattt
     1141 tgcctacaga taaaacgatg cgctcttata ttatggcttt aaattaaagg agaatacaca
     1201 tgacacctac gcaattaaaa gcaaaagtga agaatatttc tagagaaaaa gaagttgatc
     1261 cgcagcttgt tttaagacat tttatgatgg aaaaattctt ggaaaaaatc tcagagtctc
     1321 cttatcgtga aaattttgtg ttaaaaggcg gcttcttaat tggctcaaag tatggcattg
     1381 aaaatcgaac aactaaagac attgatacga ctttacggga aatgaaagta accaaagaaa
     1441 cattgacaac ggttctaaac gatatttttt caacgccgac gaaagaaggc attcaatttg
     1501 agattcaagg aatgaaagaa acgagggaag ctgattatta tccagggttt agcttacgtg
     1561 tactggcaca tttggaaaac atgcggccag attttaaggt agatgttact acaggtgact
     1621 cgatctatcc tgcgacgatc actcacagtc ataaattgat gtttgaggat cgaacgattc
     1681 ctttggaatc ctatcctaca gaacaaatta ttgctgaaaa attaagtgca acctttgatt
     1741 ttttaacaga taattcgaga ggaaaagatt tttatgatct ctatactatt cctaaaatgg
     1801 agaagatcga tgagaagacc ttgaaagata gtgtgagaaa tacatttaca cgtcgaggaa
     1861 aaactgatcc gttaaagata tactatgaaa aggatatgga tgtactgaaa aatagtcacg
     1921 agctaaaaga tacctggaag aaatatcaaa aaagcaatcc ttatgctgcg tcgatcacgt
     1981 acgatgagac aatggattcg attagtaatt tgatggaaaa agtgattcac gtcgaagaaa
     2041 aagagcgaaa actagcttat caaagacacc aacagatgaa tagagaaatg gagagataaa
     2101 gatgattaat aatgtgacat tagtaggacg cttaaccaaa gatcctgatt tacgttatac
     2161 cgcaagtggt actgcagtag cgacttttac cctagccgtc aaccgaaatt tcacgaatca
     2221 aaacggcaat tgagaagccg attttattaa ctgcgtgatt tggcgcaaac cagcagaaac
     2281 aatggcgaca ttagctaaaa aaggtagctt gattggtgta gttgggcgga ttcaaacgcg
     2341 gacttacgac aaccagcaag gacaacgtgt atatgtgact gaagttgtag cagataactt
     2401 tcaactatta gaaagtaaag cagcgacaga gagccgtgcg cacgctgatc aatcgtccac
     2461 cagtccaagc accgccacct ttgaacaacg gaatacagcg acgcctaaca acaatggatt
     2521 gaacgcttca cagaatccat ttggtggaca atcaatcgat attagcgatg atgatctacc
     2581 gttttagttt gagaaagaag gagtaagcat ggcaaaaaaa ttagtctgac gatggatcta
     2641 ttgatacccg taattgcatt tatagacggg atttctttgg gcgtcactga aaatcctttg
     2701 gtaaatagaa ttgcgaaagg atcactattt cttgtattcg tgtatcttgt ctgttcttat
     2761 cttttaaaaa gagcaggaaa ggataattcc ttttggcgat tgactaaagt cacagtagca
     2821 gcgacagctg ttatacttac ggctattcta ccgctttata tgtagagtta acgggaaatc
     2881 gttgaacttc ttgcgaaata ttgctataat gaacatgaaa aagaggagtt gcgctaacaa
     2941 cccctcatta acagcaccga ttaaagaacg gtggcagaat attagttatt tggaaataac
     3001 cgctgacctg ctaaagtaga cggttatttc tttttgtcat ttttaagcat atttacaatc
     3061 aaactaatca aagcaatggt aaacatacca aaaccaagaa tggtttgaat tgtctcatat
     3121 gcggacaaaa ggcttactcc tttcatagat tttagcactt acattcataa gcaccaccac
     3181 ctttccagaa gtcgccaccg tcttcaaact ttactgtctt gactattata gcatatctaa
     3241 aatcgaataa aaattctcaa ttttagctgt ttttgctata attttagcga ggtgatcgtg
     3301 atggaacaat atattggttt actcgataaa ttagggtgat caagacacag ccattgcttg
     3361 tgcgatttac attacgcacg agtcatgaac caatcaattg tgtagtggcc aatatagaaa
     3421 tagcggataa attgctgatt ttggaagaag gcaagtatac tatttcagtg acaggtcact
     3481 tcaataaacg aaagcaacta gtcattgaat caatgcaaat tagaaaccct gatcatttta
     3541 cgcgatcgat gagcatataa aagaagagct gcagtcctaa atgaggattg tagctctttt
     3601 tgttttacat agaaacagta aaaatgaaaa ggcctgttta ggaaggcaca agcgccttct
     3661 caattgaaag acctttctct cactccaacc gccaccgccg ttcgagaaga aaggaagtga
     3721 acgctacgcg ttcactaaga taaagggtct tgcatagcaa gacaaaatag aaaaaatttc
     3781 ctctcaccaa aaggttcgct cctgttcgtt atctctttat tgatttgtca gaccggcaac
     3841 aagttgcctt ttatcaccaa aaagcgacaa ggacaagggt aaatggcacg ctgcgcgccc
     3901 ttgtcttgtc gcttttcgtt gattcattct ggccaacaaa tcaataaaga aagaactaac
     3961 gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat
     4021 tattggggtg ttcccttcag cgaattattc ccaaactatc atgcaccaca tactgtcgaa
     4081 tgcgattgtg gagaaagagc gaaatgtatc aaaagctatt gtttgtatca atgtccaaca
     4141 tgcgggaaaa aatatacctt gtcttatggc gattatattt taattgatga gaaaggaaag
     4201 aaacgctgat gaaaacacaa cacaaattat tgactgtaaa agaagtcgtt caaattttgg
     4261 tggacaaaga agtcatttct gaaaaagtag cagaagtttt acttattccg cggtactgga
     4321 cgatagaaac ccctttagta gaggatgcac cgactatgct atttgaagac ctagtgaaga
     4381 ttgcaggata tgaactgcat tatcaagaaa acttggaaac ttatgaaaac gaatattggt
     4441 taaccaaatt agagaactaa aaaggagaaa aaaatatggc tcaaaattac tatgacgaat
     4501 ttgtcaaatt acctttggat aaaatggcac aaaaaatgga ggatatgacg ttcctataca
     4561 acgaaacacg tgttccaaaa aaacattata aagaaaaatt gtcggtagct gtggaagaaa
     4621 tgattgaata aggtgtcgaa atgaatctta ttgcgacgta ctatcgaaca ctggaagaac
     4681 tgaaaaagca aaatgcaaaa tggtttttcc aagccttact atgcttggaa gtaggtgtca
     4741 aaccaagcac tattaaacct tctgaatacc aagctttaga actaacgtat gcgaaattta
     4801 tcgaaacgaa aaaagccaag actgtttcaa gtgaatggtt agattatttt gaaaatatca
     4861 ataagtatgg cgcatattac accatgaaaa aggaagacaa cgaaaatgaa taaggtgatt
     4921 tatcaactaa caacggattc catatcaacg atttgaaaga aaaaaaggtc aataatcatt
     4981 tataccgaaa agtgagaatg tgtgaaacaa ggacaaaaaa agcctagtaa ctaaggaaat
     5041 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataaa
     5101 cgggcaaagc ccgataactt aagagaaaga aggtgatcca tttgaacaag attattccct
     5161 tattgttagt actgtttgtt ggcgaaatac ttatgcgaga tagtgcagct gtacagttaa
     5221 acctcgctgt atttttggta atactggtgt tttgtttgat cttttggcgg tttgtattag
     5281 tcctcgtgag tctactattc aagatgattg cagccatatt tttcataggg ttatttcgat
     5341 gaaaggagtg agtaccaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
     5401 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtatggcaaa agtgaatcta
     5461 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatgtac
     5521 cagcgctaaa aaagtgacgt cactttttaa tttgatctat ataagtgata tcacttttac
     5581 caaggaggga attaaatgtt aaaaactaaa aagaattcgt acaaattaaa gcttagtata
     5641 ctatctatta tttgtctttt aggcatgata attagtggtc atttgtatag agtggcatat
     5701 acgcagttta ttgagtacaa ggttcactct ttaggattag ctggggatcg atacgttgaa
     5761 tatgtccatt attcattaaa atgttcttca tatattcttc tttggcttat tttttcattg
     5821 tttgaattgc taaatttaat agcaatatct tcatatcact tagataagct aaataccaaa
     5881 tctagccgtt ataacgaagt gtttaaggaa aatgtgaagt tagaaagtga cttaaacaag
     5941 ctaaaaaaat aaaaagaaga aaacataagt taactaaaat tattttatta agaatgatgg
     6001 aatataagga taaggttacc aacataacga tcattacttc tctgatatgc tatggacttc
     6061 tatcaatcag tattttgtct atagattatg gagtaactat actgcaagcc ttagttttgg
     6121 ctatgcctat gtatctatct ttgtttatca tgcatgaaat atataagcta tttgttttat
     6181 caaaaaatgt agaaatacgg gtaaatattt tggtgaatag ttatcaaaaa gaactcaaag
     6241 aaagaagacg gtggcggtat ttattgaaag gatgaaaaag taggatttga catactggta
     6301 ttcagaaagt gccgtcactt ttaaaacaat ggaaaaggtg gagataagat gaagaaaaaa
     6361 caaactaaac tatcattagc agatatttaa cacagttaac cgcaactgaa gatggtgttg
     6421 ttgaatttga acaatctgaa attgcggtag tagatgatcg ttaccttaaa atgccttact
     6481 tctttgacca agcaaaggtc atttgccttt gtcactacga tggggtacgt gattttaggc
     6541 gttaaaaagt agtgattata tcaactttac gagtaaatat aaatttagac atgaaactga
     6601 attatccaat ggaaaatcat ggtttataat ctagaaaaat tatagtaatg attggattat
     6661 atatattctt tcgtattttc gtacaactgt agcttgtcaa aattgagaaa tttaaccgat
     6721 taggtacttt acatcgttat ttgggtaatt tctaaaacat gaagcttacc aacgaataaa
     6781 ctgagactat cttattaatt gatcaatata agaaaatatc tttgaggaga tgatgtacta
     6841 tgttttcgtc tatccacgat tggttaggtg gtcttttcgg cggtggaggt aaaggttttt
     6901 a
//
LOCUS       DARPZJ010000093         6673 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.099, whole genome shotgun sequence.
ACCESSION   DARPZJ010000093 DARPZJ010000000
VERSION     DARPZJ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.099"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            71..154
                     /locus_tag="SLE23_002638"
     CDS             71..154
                     /locus_tag="SLE23_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEI8469481.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            279..1016
                     /gene="erm(B)"
                     /locus_tag="SLE23_002639"
     CDS             279..1016
                     /gene="erm(B)"
                     /locus_tag="SLE23_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEI8469482.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1186..1446
                     /locus_tag="SLE23_002640"
                     /pseudo
     CDS             1186..1446
                     /locus_tag="SLE23_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1609..2274
                     /locus_tag="SLE23_002641"
                     /pseudo
     CDS             1609..2274
                     /locus_tag="SLE23_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2310..2555
                     /locus_tag="SLE23_002642"
     CDS             2310..2555
                     /locus_tag="SLE23_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8469483.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2658..3527
                     /locus_tag="SLE23_002643"
     CDS             2658..3527
                     /locus_tag="SLE23_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEI8469484.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3508..4242
                     /locus_tag="SLE23_002644"
     CDS             3508..4242
                     /locus_tag="SLE23_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8469485.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4275..5190
                     /gene="ant(6)"
                     /locus_tag="SLE23_002645"
                     /pseudo
     CDS             4275..5190
                     /gene="ant(6)"
                     /locus_tag="SLE23_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5187..5729
                     /gene="sat4"
                     /locus_tag="SLE23_002646"
     CDS             5187..5729
                     /gene="sat4"
                     /locus_tag="SLE23_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEI8469486.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5822..6616
                     /locus_tag="SLE23_002647"
                     /note="aph(3')-IIIa"
     CDS             5822..6616
                     /locus_tag="SLE23_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEI8469487.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2340 a         1005 c         1393 g         1935 t
ORIGIN      
        1 ttttgtgtat aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga
       61 gggattcgtc atgttggtat tccaaatgcg taatgtagat aaaacatcta ctgttttgaa
      121 acagactaaa aacagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg
      181 actaatctta tgacttttta aacagataac taaaattaca aacaaatcgt ttaacttctg
      241 tatttattta cagatgtaat aacttcagga gtgattacat gaacaaaaat ataaaatatt
      301 ctcaaaactt tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa
      361 aagaaaccga taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg
      421 ctaaaataag taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt
      481 cagaaaaatt aaaactgaac attcgtgtca ctttaattca ccaagatatt ctacagtttc
      541 aattccctaa caaacagagg tataaaattg ttgggagtat tccttaccat ttaagcacac
      601 aaattattaa aaaagtggtt tttgaaagcc atgcgtctga catctatctg attgttgaag
      661 aaggattcta caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc
      721 aagtctcgat tcagcaattg cttaagctgc cagcggaatg ctttcatcct aaaccaaaag
      781 taaacagtgt cttaataaaa cttacccgcc ataccacaga tgttccagat aaatattgga
      841 agctatatac gtactttgtt tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta
      901 aaaatcagtt tcatcaagca atgaaacacg ccaaagtaaa caatttaagt accgttactt
      961 atgagcaagt attgtctatt tttaatagtt atctattatt taacgggagg aaataattct
     1021 atgagtcgct tttttaaatt tggaaagtta cacgttacta aagggaatgg agataaatta
     1081 ttagatatac tactgacagc ttccaagaag ctaaagaggt ccctagcgcc tacggggaat
     1141 ttgtatcgat aaggggtaca aattcccact aagcgctcgg gaccccttgt aggaaaatgt
     1201 cctaagtgtg gcaacaatat tgtattaaaa aaatcgtttt atggttgttc aaattatcct
     1261 gaatgtaagt ttactttagc tgaacatttt agaaagaaaa aactaaccaa aacgaatgta
     1321 aaagaattac tggagggaaa agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag
     1381 ccctacaatg ccgttgtaaa aattggggaa aagggatata ttgattttat ctctttttca
     1441 aaataaacat ggggctgacc caaaagtagc tcctatatga aaaatagagg tctttccatt
     1501 tagatagtag tggaaagacc tctatttatc ttttgaaagt gaatacaaaa ataaagcaca
     1561 ctctgctata atataggtga ttaatccatt tgagagaggt gctttatcat gtatcaaaat
     1621 tataccataa accaactttg tttgcctata gatcttgaaa ttaaattaga agaaaatgat
     1681 tttgctcatg ccattgtgca gtttgttgac tctattcccg atgaagtctt tcttccttat
     1741 tatcaatcta tgggtagacc ccaatatcat cctcgtatgc tactttccat tattctttgt
     1801 gcctatattc aaggggttta ttcgggccgc caaatacaaa atatgctgat agatagtatt
     1861 cggatgcgct acttatctca agagcaattc cctaactttc gtactattaa tcgttttcgc
     1921 gttcatccga ttatgaacga tattctagat cattcatttg ttcaatttcg tgagctactg
     1981 gttcaaagtg gcttaatcag tggcagtgct ctatacattg atggtacaaa aattgaagcg
     2041 gatgcgaata aatactcttt cgtttggaaa aaaagtattt taaagtataa ggatagcctt
     2101 gatcaaaaag cccttgaaaa ctaccaacaa atggtggaaa caaaaatctt acctgagtta
     2161 atagatgatt taaaggatga actttctata gaagagattg aaaggattcg tcaatctttg
     2221 gaagaaaagg aaaatcaatt aattgaagcg attgaccaaa ccgaaacagt agaagggggc
     2281 tgacccatta ttaataagga gtggacaaca tgattgatgt aaatgagcta ttggaagaag
     2341 ctattagaga aactgaaaat ctaaatgatg gcgaagtttt tcttgttaaa gatttattca
     2401 agggatatgt ggggaatagg atacccagaa aggatcgact tctgcttgga acgttatttt
     2461 taaaccatgt tagcaaaatg aatggtaatt taaaggctat tgaaaagact tcatctaatc
     2521 agcagaggta taaaaagaca attgataagt tttaactatc ttttgtgaaa ttaaaaaaat
     2581 tataaatatg ttgagtagaa gcaaaagatt tggcttggaa tttttacagc agtgaatcga
     2641 taaaaggagc atgcttgatg gtagataata ttattaaatc agtagcagag aaattatcct
     2701 ctctgtctta tatagaaggt attgttttag gtggttcacg tgcaaggggc acccatacag
     2761 aggattcgga tatagatatc ggcatctatt acaattcaga atcatttgac ataaatacta
     2821 ttaatcaatt cgctacaaag ctggatgatg agcatagaaa taaccttgtt gtacctcccg
     2881 gagcatgggg tgattggatt aatggcggcg gatggttagt cataaacggg tatcatgtgg
     2941 atttaatttt acgtgatatt aaacgtgtgg aacaaataat gaaagataca gagcacggaa
     3001 ttgttactgc caattatcag actgggcatc cccatggtta tattagtgca atgtatcgag
     3061 gagaattagc gattagcaaa atactatatg ctaagaatga aagcttatgc gaattaaaaa
     3121 aacaggcaga aacttatccc aatgctttgc agaaaagttt agttaacttt tttatgtttg
     3181 aagcagggtt ctctttaatg tttgtaaaag caaattcggg aacagacgat aaatattata
     3241 ttgcgggtca tgtttttcgt atagtttcat gtttaaatca agtgttattt gcatgtaata
     3301 atgcttattg tatcaacgaa aagaaagcta taaaactgct tgaaactttt gaacataaac
     3361 ctgaaaaata taccgagaag gtaaatcata tttttgaagt actcggtatc tcactttttg
     3421 aatgctacga catgaccgag aagctttata atgaagtgaa tgaaattgta tcggagataa
     3481 ataacttttt aaacgaggag agttcagatg aaagaaaaca aatatgatga taatatattt
     3541 tttcaaaaat acagtcaaat gagtcgctcg cagaaaggac tggctggtgc gggagaatgg
     3601 gagactttga aaaagatgct acctgatttt aagggtaagc gtgtgcttga tttaggatgc
     3661 ggctatggat ggcactgtat atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt
     3721 gatatttctc ataaaatgct cgaagtagca aaaggaaaaa cccattttcc acagattgaa
     3781 tatgaatgct gtgccataga agatgtggat ttcccagagg agagctttga tgtaatacta
     3841 agttcgcttg cgtttcatta tgtagcagac tatgagaatt taataaaaaa gatatatagg
     3901 atgctgaagg ctggtggcaa tttagttttt acagttgaac atcctgtttt tactgctcat
     3961 ggaacacaag actggtatta taacgaaaaa ggagaaatac tgcatttccc ggtggacaat
     4021 tattattatg agggcaaacg gacagctatg tttttggaag aaaaggttac aaaatatcat
     4081 agaacactga ccacatatct aaatacactg ctttcaaata gttttataat aaatcagatt
     4141 gtggagccac agccgccaga gaacatgatg gatattccgg ggatggcgga tgaaatgcga
     4201 cgcccaatga tgctgattgt atcggcaaaa aagaagatgt aataatatag aaaaaataaa
     4261 cgaggagtat gtaaatgaga tcagaaaaag aaatgatgga tttagtactt tctttagcag
     4321 aacaggatga acgtattcga attgtgaccc ttgaggggtc acgcgcaaat attaatatac
     4381 ctaaagatga atttcaggat tatgatatta catattttgt aagtgatata gaacctagaa
     4441 ccgtttatat ctaatgatga ctggcttaat caatttggga atataataat gatgcaaaag
     4501 ccggaggata tggaattatt cccacctgaa gaaaagggat tttcctatct tatgctattt
     4561 gatgattaca ataaaattga tcttacctta ttgcccttgg aagagttaga taattaccta
     4621 aagggcgata aattaataaa ggttctaatt gataaagatt gtagaattaa aagggacata
     4681 gttccgactg atatagatta tcatgtaaga aagccaagcg caagggagta tgatgattgc
     4741 tgcaatgaat tttggaatgt aacaccttat gttattaaag gattgtgccg taaggaaatt
     4801 ttatttgcta ttgatcattt taatcagatt gttcgccatg agctgctgag aatgatatca
     4861 tggaaggtcg gcatcgaaac aggctttaaa ttaagtgtag gcaagaacta taagtttatt
     4921 gaaaggtata tatccgagga tttgtgggag aaacttttgt ccacctaccg gatggattcc
     4981 tatgaaaaca tatgggaagc attatttcta tgccatcaat tgttcagggc ggtatccggt
     5041 gaggtggcgg aaaggcttca ttatgcctat ccggagtatg ataggaatat aacaaaatat
     5101 accagggaca tgtataaaaa atacactggt aaaaccggct gcctggatag cacatatgcc
     5161 gctgatatag aagagaggcg ggaacagtga ttacagaaat gaaagcaggg cacctgaaag
     5221 atatcgataa acccagcgaa ccatttgagg tgataggtaa gattataccg aggtatgaaa
     5281 acgagaattg gacctttaca gaattactct atgaagcgcc atatttaaaa agctaccaag
     5341 acgaagagga tgaagaggat gaggaggcag attgccttga atatattgac aatactgata
     5401 agataatata tctttactac caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa
     5461 attggaaccg gtacgcttat atagaagata tcgccgtatg taaggatttc agggggcaag
     5521 gcataggcag cgcgcttatc aatatatcta tagaatgggc aaagcataaa aacttgcatg
     5581 gactaatgct tgaaacccag gacaataacc ttatagcttg taaattctat cataattgtg
     5641 gtttcaaaat cggctccgtc gatactatgt tatacgccaa ctttgaaaac aactttgaaa
     5701 aagctgtttt ctggtattta aggttttaga atgcaaggaa cagtgaattg gagttcgtct
     5761 tgttataatt agcttcttgg ggtatcttta aatactgtag aaaagaggaa ggaaataata
     5821 aatggctaaa atgagaatat caccggaatt gaaaaaactg atcgaaaaat accgctgcgt
     5881 aaaagatacg gaaggaatgt ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa
     5941 cctatattta aaaatgacgg acagccggta taaagggacc acctatgatg tggaacggga
     6001 aaaggacatg atgctatggc tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga
     6061 acggcatgat ggctggagca atctgctcat gagtgaggcc gatggcgtcc tttgctcgga
     6121 agagtatgaa gatgaacaaa gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag
     6181 gctctttcac tccatcgaca tatcggattg tccctatacg aatagcttag acagccgatt
     6241 agccgaattg gattacttac tgaataacga tctggccgat gtggattgcg aaaactggga
     6301 agaagacact ccatttaaag atccgcgcga gctgtatgat tttttaaaga cggaaaagcc
     6361 cgaagaggaa cttgtctttt cccacggcga cctgggagac agcaacatct ttgtgaaaga
     6421 tggcaaagta agtggcttta ttgatcttgg gagaagcggc agggcggaca agtggtatga
     6481 cattgccttc tgcgtccggt cgatcaggga ggatatcggg gaagaacagt atgtcgagct
     6541 attttttgac ttactgggga tcaagcctga ttgggagaaa ataaaatatt atattttact
     6601 ggatgaattg ttttagtacc tagatttaga tgtctaaaaa gctttaacta caagcttttt
     6661 agacatctaa tct
//
LOCUS       DARPZJ010000094         6644 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.100, whole genome shotgun sequence.
ACCESSION   DARPZJ010000094 DARPZJ010000000
VERSION     DARPZJ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.100"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(1..859)
                     /locus_tag="SLE23_002648"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="SLE23_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="SLE23_002649"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="SLE23_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEI8469488.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="SLE23_002650"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="SLE23_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="SLE23_002651"
     CDS             complement(2143..2373)
                     /locus_tag="SLE23_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HEI8469489.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="SLE23_002652"
     CDS             complement(2603..3421)
                     /locus_tag="SLE23_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEI8469490.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="SLE23_002653"
     CDS             3582..4271
                     /locus_tag="SLE23_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEI8469491.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="SLE23_002654"
     CDS             4285..5787
                     /locus_tag="SLE23_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8469492.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="SLE23_002655"
     CDS             5800..6276
                     /locus_tag="SLE23_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8469493.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="SLE23_002656"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="SLE23_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DARPZJ010000095         6462 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.101, whole genome shotgun sequence.
ACCESSION   DARPZJ010000095 DARPZJ010000000
VERSION     DARPZJ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.101"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(109..564)
                     /locus_tag="SLE23_002657"
     CDS             complement(109..564)
                     /locus_tag="SLE23_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469494.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(718..1926)
                     /locus_tag="SLE23_002658"
     CDS             complement(718..1926)
                     /locus_tag="SLE23_002658"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEI8469495.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2038..2370)
                     /locus_tag="SLE23_002659"
     CDS             complement(2038..2370)
                     /locus_tag="SLE23_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEI8469496.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2518..3393
                     /locus_tag="SLE23_002660"
     CDS             2518..3393
                     /locus_tag="SLE23_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEI8469497.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3475..4056)
                     /locus_tag="SLE23_002661"
     CDS             complement(3475..4056)
                     /locus_tag="SLE23_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HEI8469498.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4062..5321)
                     /locus_tag="SLE23_002662"
     CDS             complement(4062..5321)
                     /locus_tag="SLE23_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEI8469499.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5323..6369)
                     /locus_tag="SLE23_002663"
     CDS             complement(5323..6369)
                     /locus_tag="SLE23_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469500.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1799 a         1338 c         1102 g         2223 t
ORIGIN      
        1 aaatcttgtc acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag
       61 taataagaca catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa
      121 ttccccgtat acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt
      181 tttttcgctg atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag
      241 atatgggaag tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat
      301 atcttcgtat ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc
      361 atgtgtcgca actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg
      421 gatttcaaca aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca
      481 aagatcgccg atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt
      541 tagcgctgtc atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta
      601 ctacctcagt ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg
      661 acgtatctgc ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta
      721 aatcaatttt tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg
      781 ttctacgacg gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt
      841 tccagtttct tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg
      901 taaacgatca taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat
      961 caattcttct acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa
     1021 agctccagtt tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt taatcatttg
     1081 gttagaacac ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg
     1141 gctgatcaat aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc
     1201 aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt
     1261 ttcaataaat gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc
     1321 cacatttata cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta
     1381 gaaggtttct tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat
     1441 tcgtaaggca tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc
     1501 ttctagatct tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa
     1561 cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac
     1621 atgatctggt ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata
     1681 ttgttcatca ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt
     1741 tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat
     1801 tggctggttc agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc
     1861 attctctaat tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa
     1921 tttcattttt ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg
     1981 gtgactgttt gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta
     2041 ctcgtcctta cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc
     2101 aaaaacttca gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac
     2161 atcaccaagt tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc
     2221 ataagtgtgg ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg
     2281 agctaatgga gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg
     2341 catactgtat aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa
     2401 ctttaacgca aatcctagat aagagcactt gagaaaatcg aatttccatg ctacatttag
     2461 gaaggaattt ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg
     2521 gtcaaacgaa aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca
     2581 tttggtcttg tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc
     2641 accttgatct taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac
     2701 atcccattga ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt
     2761 ctaggtacac tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc
     2821 aatttacagc atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga
     2881 agcgggatcg tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt
     2941 ttagaacaaa attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc
     3001 ttacttgctt cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg
     3061 tatgttttca gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta
     3121 cttgtcgtct ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga
     3181 ggtgtgactt tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat
     3241 atggtcgtta gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa
     3301 aaagctttcc tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg
     3361 aagccacaga caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg
     3421 aaagattcca catccagctg acctttgtct tttttagtac tatactattt ttaactaatt
     3481 gttatgttca cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac
     3541 ttcatcagat aatttcaaaa aagcatccct atctccatct tctagtgctt gatcgatttg
     3601 agcataaagc atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa
     3661 ttcagtatct tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat
     3721 agatagatat tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt
     3781 tttccaattc aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg
     3841 caaaaacaat ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc
     3901 cgcaaaattc gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag
     3961 ataattcaag atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt
     4021 taaaaaattc ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca
     4081 tctaataatg acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat
     4141 tcttgcgctc ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa
     4201 tctggttcat gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag
     4261 tcttctaatt cattataagc atgggctagg ttccattctg cataaggatt agcagtttct
     4321 tccatctgat tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta
     4381 cttaaagtaa gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt
     4441 tcttctgctc gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt
     4501 tcgacttggt aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc
     4561 atttcttctt cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta
     4621 acttctcgaa gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc
     4681 gtaaaagcta gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa
     4741 ggtacgatag ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc
     4801 atcgagattc ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct
     4861 gcctctttga aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt
     4921 tcatcaggaa gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg
     4981 ataacttggt acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta
     5041 tccacttttt ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct
     5101 gctaacggga tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc
     5161 tgttttgctt cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata
     5221 tctgctgggt cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca
     5281 tctgataaag cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc
     5341 actgacgatt tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg
     5401 gtatccgtct attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa
     5461 aaaaagaact ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata
     5521 gccaagcaag tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg
     5581 gagattccac acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag
     5641 atggccattt tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt
     5701 ttctgcctct aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt
     5761 cgttaattgc tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca
     5821 aatcattccg caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc
     5881 gctgattgtt tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg
     5941 atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga
     6001 tacagggatc atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag
     6061 atccatgatc ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg
     6121 tttgacgaaa tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca
     6181 aatataccag tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa
     6241 atcataatag cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag
     6301 ctgactgact agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc
     6361 aagttccata cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta
     6421 gaaaagataa gagcaaagct cacctcataa cttggaaata aa
//
LOCUS       DARPZJ010000096         6447 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.102, whole genome shotgun sequence.
ACCESSION   DARPZJ010000096 DARPZJ010000000
VERSION     DARPZJ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.102"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..115)
                     /locus_tag="SLE23_002664"
     CDS             complement(<1..115)
                     /locus_tag="SLE23_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEI8469501.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="SLE23_002665"
     CDS             246..698
                     /locus_tag="SLE23_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469502.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="SLE23_002666"
     CDS             712..1401
                     /locus_tag="SLE23_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469503.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="SLE23_002667"
     CDS             1526..3877
                     /locus_tag="SLE23_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HEI8469504.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="SLE23_002668"
     CDS             3957..4352
                     /locus_tag="SLE23_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469505.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="SLE23_002669"
     CDS             4677..5294
                     /locus_tag="SLE23_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8469506.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="SLE23_002670"
     CDS             5335..5634
                     /locus_tag="SLE23_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HEI8469507.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="SLE23_002671"
     CDS             5668..5835
                     /locus_tag="SLE23_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEI8469508.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6443)
                     /locus_tag="SLE23_002672"
     CDS             complement(5880..6443)
                     /locus_tag="SLE23_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8469509.1"
                     /translation="MIFKLRNRTEGLNIDKLFQEKASGKDTERPEFQKLLNYIREGDC
                     VIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLDTAMFDMFLSL
                     LSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQ
                     GIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2210 a          903 c         1276 g         2058 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttcggtt
     6421 ctgttgcgaa gtttgaaaat caaacgc
//
LOCUS       DARPZJ010000097         6288 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.103, whole genome shotgun sequence.
ACCESSION   DARPZJ010000097 DARPZJ010000000
VERSION     DARPZJ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.103"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..177
                     /locus_tag="SLE23_002673"
     CDS             <1..177
                     /locus_tag="SLE23_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469510.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..691
                     /locus_tag="SLE23_002674"
                     /pseudo
     CDS             190..691
                     /locus_tag="SLE23_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
     gene            788..2635
                     /locus_tag="SLE23_002675"
     CDS             788..2635
                     /locus_tag="SLE23_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HEI8469511.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2638..3534
                     /locus_tag="SLE23_002676"
     CDS             2638..3534
                     /locus_tag="SLE23_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8469512.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3584..3973
                     /locus_tag="SLE23_002677"
     CDS             3584..3973
                     /locus_tag="SLE23_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8469513.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3960..>6288
                     /locus_tag="SLE23_002678"
     CDS             3960..>6288
                     /locus_tag="SLE23_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8469514.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1350 g         1887 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg ggggcatggt ttaccccacc cgtcgatttt gatgaagtga aagaacggat
      301 tggattaaat gacgaatatg aagagtacgc aattcatgat tatgaactgc cttttgagat
      361 tgatgagtat acaccaattg aggaaattaa tcggttgtgt ggtttagcgg aagagcttaa
      421 aggaacgcca attggtgagg tcgcttcaga gattcaacat gccttcttca attctttcga
      481 ggaaatggta gagcatgtgg atgatatcat ctattatccc gattgtaatg acatgagtga
      541 tgtagcgtat tacttgattg tagaagctgg tgatttaggc gaagtaccag aacacttgaa
      601 gacgtatatt gattttgatg cgtgtggtcg agacttggag attggcggga attatttggt
      661 tacgagtcga ggggtttttg aactaatgta aatcatttgt tagaattgac cagaaatttc
      721 tatcgtactt ttacttttct atttgatata ctgaaataga aaatatttgt tgataggggt
      781 gttactaatg gttggcaata agtggtacaa atgtgatctt catattcatt caactgcgag
      841 tcagtgcttt caggataaaa aggttactgc taaggaatgg gtagaagaat gtttaaacaa
      901 aggactcgat tgtgttgcat taactgatca caatacaggg gaaaatattg atgaatataa
      961 gaaagtggct atcgaaaatg gcttagattt ttttcctgga gtggaattaa cgtgtggaga
     1021 aaatggaact catttactag tcctatttga taaaagtgca tgtacaaatg atatctctga
     1081 tttcttaacc aagatgggta taaaaagaga ggattgggcc agcgctgcag cttgctcaat
     1141 gaaatcagtt ttagaagtta ttgattttgc tgagcacgag ggcttgctcg ttattcctgc
     1201 acatatagat gagtttaatg gaatttcttc agcaaaattt ggaaatctag gaaagatatt
     1261 tgaatcagaa aatatatatg cagtacagac ggttcaaaaa gaattttttg aaaatcgctc
     1321 acaaatgatt ccctcatcta agcgtgacac tatctatgat agtgtgaatg ccagatatga
     1381 tggtagagtt ggaaaagata ctttggaatc ttggtataaa tcagttgttg aggcagaaaa
     1441 aaataatatg acatttctta gcttttctga taacccacac tcgaaaggaa attcaaaaca
     1501 tggactttgg ggaataggca caagatattc ctatataaaa atgaaggacg aacctgactt
     1561 gggatcactt cgcgatgctt taatgctagg cgaaactcga gttcattctg atttttctaa
     1621 tttctccatt aatgaaaatg aagttttatt ggaaaaatta agcttttctg ggaccactct
     1681 tagcacaaaa gaagttgtag tcgaattcag cgataattta acttcaatta ttggaggaag
     1741 aggaacaggc aaatcttgta ttacaagatt cttggtctat gtccttggaa aggaagcaga
     1801 acttgatcaa ttttctgaaa tacaaagtga ttatcagaac tttgcacaaa ttgaacataa
     1861 tggctctgga atatttttga aggatacaat tgtgaaactg aatattttct ataaggggac
     1921 aaaatatcaa ataataagaa cacaggatag acattctatt tatgaattta cacaagagaa
     1981 tggtctggtt gaaaaagaaa cagaacggtt gagaatgatt tccgataagg tgagtatata
     2041 ctctcaaaaa caaatttatg aaatttcaaa aaatcaaact agtatactag aattactaga
     2101 tggatataac tctgatttga tttcagagta taaaaatgag attgaaacat gtgtaaacga
     2161 aataagaaaa ttaaattggg atattgtttc tgtgaaaaaa gaaatacaag ataaggcgaa
     2221 ggtagagctt gaaattgaag atttaaaaaa acaagtagaa aagctatctc ataagagtta
     2281 taaagatgtt tatgatgagt attcaaaaga gacagatatt tatagggaac tgaaacgtga
     2341 tgtggaggca cttaaggaaa ttcccaaaaa tctaactgat agtgttgaca aaattgactt
     2401 tggcaatggt ataaaagtta cagacgaaat tgatgaacac cgcggagaat tgattaagaa
     2461 tttagtgacc aatcgggcta agattcaaac aataattaat gaaatgtcag atgaaattga
     2521 tagttataga gcagagctga ataaatcaga ttggaaagtt aactataatg aggtttcaaa
     2581 gaggtatcaa agaggtatca aaaacttagt gaagagttat ctcaagatga attaaaaatg
     2641 ttacaaaacc ttgattcttt atatcaatct ttatcaaaaa ctgaagagcg attggaagaa
     2701 attattcaac aagaaataaa gcttaaagat taccaagttg aggttgactc agcaatgtca
     2761 agaatgaata aatcatatca aaatctctat tctgagagaa gtagttcctc gcgcgaaatt
     2821 ttttctgata ttacaggaat agaggctact attcaaccaa atagggattt caataattat
     2881 gttaaagagc tcagagcttg tattaataag gaggacactt ttgacagtga gtttggatct
     2941 cttattgata agctgacaaa aaattccatt actaatcaag atatatataa tgacatactt
     3001 gatataagag ttagtgggga aagtagtatt ttttcagata aaaaattaat caattctata
     3061 agaaaattga atgatgcaca agttcttgaa ttacaaaccc ttaagccaaa tgatttagta
     3121 gttatccgac ttgaactaaa tggaaaaaaa gttagtttat cgaatgctag tgctggtcaa
     3181 aagacatctg caattctttc tatgattttg gcgtatggaa attcaccact catattggat
     3241 cagcctgaag atgatttgga tagtcaatta attaataact taatcgtaag aagtatcatt
     3301 acaaaaaagg aaaacagaca aattttaatt gtaactcata atgcaaatat cccagttaat
     3361 ggtgattcag aatggttgat tagcatggga gattcaaaag aaatatcggc tgatcagtgc
     3421 gggtcggtag atgaacccaa tatcaagcca agaatatgta ctgtgatgga aggtggcgag
     3481 gatgctttta caaatagagc gaaacgctat ggttttaaac aaattgtaga ataacactag
     3541 agggtgagac atattattat gtccgccctt tttaggagga aaaatgaaaa aaataaaaag
     3601 ctataccagt atctgggcag ttgaaaaagt catttacgca atcaatgatt ttcagttgcc
     3661 ttttcctgtg acttttaacc aaatggcttg gttcgtttta tctttactgt ttgtcatcgt
     3721 atttgcccat gtgcctccac tatctatgat agaggaggtc tttttaaaat acttaggcat
     3781 accggtggct gtcacttggt ttatgtcgca aaagacgttt gatggcaaga aaccactggg
     3841 atttttacga tcctttatca gctatcactt gcgatttaag gtgacttttg caggaaagaa
     3901 agtcaaagaa cagaagaaac gatgggatga acccagtact cttgtaagga gtgtgaacta
     3961 tgtatccgat taagtatatt gaaaataatc tcgtctttaa ccaagaaggc gagtgttttg
     4021 cctactatga attagtgcct tacaattact cctttttgtc acccgaacag aaatttcaag
     4081 tgcatgataa ctttcgccaa ctaattgcgc aaaatcgtga aggcaagatc catgcgttac
     4141 aaattgccac agaaagtagt attcgcgcca cacaagaacg atcaaaaaaa gaaattaccg
     4201 gtagactcaa agaagtagcg aaacaacgaa ttgatataca gacagaggca ttagtatcca
     4261 tgattggcga tagtcagatt gattatcgct tttttattgg ctttaaacta attgcgacag
     4321 atgaagaagt caatctaaag agtctcaaga aatctttctt ttctgggctt caagaatttg
     4381 tctatggagt gaatcatcat ttgatgggcg attttgtttc cttatccaat gaagaaattc
     4441 gctgctattc taagcttgaa aaattaatgg aaagcaaatt ggctcgaaga tttaaagtca
     4501 ggcgagtcac accgagtgac ctgacgtatt tgattgaaca tatttatggc gaaaaaggga
     4561 taccgtttga agaatacgaa tttcagctac caaagaaaaa gctaaaatca gaaacactgg
     4621 tgaaacgtta tgacttatta cgtccaaatc gttgtttaat tgaagaaaaa ccaaggtgct
     4681 tacggatgga acatgagaat catgagtcgt acgtagcgta tttaacaatt aatacaattg
     4741 tgggggagat ggaatttcct tcctcagaac ttttctatta ccagcaacaa caatttacat
     4801 tcccaatcga cacaagtatg aatgtagaga ttgtgacgaa taaaaaggct ttagctaccg
     4861 ttcgtaataa gaaaaaagaa ctgaaagatt tagacaatca tgcttaccaa tctgacaatg
     4921 aaacgaattc caatgtctta gatgctttgg attccgtgga tgaattggaa accaccttgg
     4981 atcagtcaaa agaatctatg tacaaactga gttatgtggt tcgagtgagt gccgaatcag
     5041 tggatgaact aaagcgacgc tgtgatgaag tgctcgattt ttatgatgat accaatgtaa
     5101 aactagtccg gccctttggc gatatgatgg ggctacatga agaattctta ccctcaagta
     5161 aacgatatat gaacgactat attcagtatg ttacgtctga ttttttggcg gggcttggtt
     5221 ttggggctac tcagatgcta ggagaattag aagggattta ctttggctac aatgtggata
     5281 caggtcgtaa tgtttacctg aaaccggcat tggcttcaca aggagtcaag ggttcagtaa
     5341 ccaatgcgct ggccgccgct ttcctgggtt ctcttggtgg aggtaaatcc tttagtaaca
     5401 atctcttagt ctactatgct gttttgttcg gtggtcaagc tgtgattgtc gatccaaaag
     5461 gggagcgagg agggtggaaa gaaaccttgc cagaaattgc ggatgaaatc agtatcctca
     5521 acttgacgag taagtcagaa aatcaaggtc tgcttgatcc ttatgtgatt atgaagaaaa
     5581 agaaagactc ggaaagttta gcaattgata ttctgacttt tttaacagga atttcaagtc
     5641 gagacgggga gaagtttcct gtgttacgta aagccattcg aacggtgact caaagtgatc
     5701 aacgggggtt attacaagtt attaacgaat tgcgaaaaga cgggtcacca atcgcggaaa
     5761 atatcgccga tcatatcgag tcctttaccg attatgattt tgctcatttg cttttctcag
     5821 acggctcgat tacccaatcg attagtttag ataaacagct aaatatcatt caagtggcgg
     5881 atttggtttt accggatgca gaaacgactt ttgaagaata taccaccatg gaattgctta
     5941 gtgtttcgat gctaatcgtc atttccactt ttgccttgga ctttatccat agtaaccgag
     6001 aaatcttcaa aattgtcgat ttggatgagg cttggagttt tcttcaagtg gctcaaggaa
     6061 aaacgttatc gaataagctt gttcgtgctg gtcgggccat gaatgctggg gtctatttcg
     6121 tcactcaaaa tagcgacgat ttattagatg aacgtttaaa aaataatatc gggttgaagt
     6181 ttgcttttcg cagtaccgat attcatgaaa tcaagaaaac cttggaattc tttggtttgg
     6241 atcaggagga tcaaagcaat caaaaacgcc tgcgagattt ggaaaacg
//
LOCUS       DARPZJ010000098         6262 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.104, whole genome shotgun sequence.
ACCESSION   DARPZJ010000098 DARPZJ010000000
VERSION     DARPZJ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.104"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(92..664)
                     /locus_tag="SLE23_002679"
     CDS             complement(92..664)
                     /locus_tag="SLE23_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8469515.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(671..1333)
                     /gene="rpe"
                     /locus_tag="SLE23_002680"
     CDS             complement(671..1333)
                     /gene="rpe"
                     /locus_tag="SLE23_002680"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEI8469516.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1349..1864)
                     /locus_tag="SLE23_002681"
     CDS             complement(1349..1864)
                     /locus_tag="SLE23_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HEI8469517.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1866..2150)
                     /locus_tag="SLE23_002682"
     CDS             complement(1866..2150)
                     /locus_tag="SLE23_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8469518.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2184..3512)
                     /locus_tag="SLE23_002683"
     CDS             complement(2184..3512)
                     /locus_tag="SLE23_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEI8469519.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(3526..3981)
                     /locus_tag="SLE23_002684"
     CDS             complement(3526..3981)
                     /locus_tag="SLE23_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8469520.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(3984..5930)
                     /locus_tag="SLE23_002685"
     CDS             complement(3984..5930)
                     /locus_tag="SLE23_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEI8469521.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         2058 a         1205 c          875 g         2124 t
ORIGIN      
        1 tattaagtta tgtctaatca aataaaaaaa ccattctcat atttgctgaa taattagcat
       61 ttagagaatg gttttttatc tttaaaatct actactcaaa atctgcatgt cgagcaaaca
      121 tcgtttctga gctttcacct gttttatcca ttaaagataa cactaaacta tcaaaggtga
      181 gaaatgctaa ttgttcaaaa cttgaaccca taggttgtga aaaagtatct tcttctcgtt
      241 gattttcatc tttggtaata cctggtaata caagaacaga atctgctaat tgaccaatcg
      301 acgagtcttt tttcatggta actaaagcaa tgcttacacc actttgattt gctttggccg
      361 ctaaattttt taaactacct gtttcacctg agccagaaca gataattaat aaatctccag
      421 gttgcgaatg tggtgaacta atttcaccga caaggctgac tgaaaaacct aaatgcatta
      481 agcgattcgt aaatgcttgc atggcaattc cagagcgtcc tgcaccagct agaaagatgt
      541 gtttagcttg aacaattttc tcactaaatt gttctaactc tacagaatta atacgttttg
      601 agttattttg taattctaag ataatcgctt ctaaatagtt tttattttgg tctttattgg
      661 tcatgatctt ttacttcact tcctctaatg attgatttag tttatcaatt tgttcttgcg
      721 gggtattttt cccattgaag atgaaaccgc ctgatacaaa aatatccgcc cctgctttag
      781 aacaaacttt aatcgtttga ttatcaatct tgccatctac ttcaatatca tacgtataat
      841 cattttgttt gcgtattaca tctaactgtt cgattttaac tactgtctct tgaataaaat
      901 gcttattctc tgttcctgga ttgattgtca ttactaatac ttgatcgact aaagataata
      961 ctggttcaat aaaactgact ggtgttgcag gattaaaagt aatccctact tttgctcctg
     1021 cttccttgac taactgaatg accttcattg cgtgtttggt agcttcaatg tggaaggtaa
     1081 caatatctgc tcctgcttct acaaatcttg tgacaatttt ttctggtgta tcaatcatca
     1141 aatgaacatc aaacacaacg tctgttagtg gacgaatatc tttaataaca cttggtccaa
     1201 aagccatatc tggtacaaaa cagccatcca ttacatcaat atgcaaataa tcaacattct
     1261 tttcttttaa gatttcaaat aactctttaa cttctgcgat aggtgcattt aacaatgatg
     1321 gagcaattgt cattctctat tcccccgttt attctcccat aatcatgaga ttgattgttc
     1381 tagttcgctc tcttagttga tcccaatcga caaaatagac acggcccatt tctcctaata
     1441 aaagtttacc ttcttgaaca attaaagtca ttgagttggt tccataaata gatgaacgta
     1501 aatgtgcatc ggtatttagc atgacccatt tttctgcagg gtaattggga tcagataatc
     1561 ttgttccaaa atcaatgtgt tttggccccg gactgttgta ttgattttca ctcgtcattt
     1621 ttggaataat cgtttccatt acattgttga tgtctacatg taaataatca tcaccaaaaa
     1681 agtttgtgtc atgcatcgtt tcttcaaaaa agagtgagca agttgtatgc gggctcgaaa
     1741 ttactaacat tccattctca atacctgctg tatcaactgt atctaaaagt tcttttcgaa
     1801 tatcatgata cgaaggacgc cctgaaactg tttcaatagt caaagtgtca tgatgaaaac
     1861 gcatattaaa cacctaatct ttcttttaca tctgcataaa tggcatctgt accaatacct
     1921 gttaataagc ccaagccatt cgttacttta gctttaatta catcagggac aattgttgta
     1981 cttactacag catcatattc atcaatttta tttagctcat cagcaatttt agattgataa
     2041 attttcactt gatctgttaa tccttcttct tccaaccatt ttgataattt tgctactgca
     2101 attgtagaag tagcatgacc tgctccacaa ataactaata attttttcat attgatctct
     2161 tctttcttat tttaatttta tgattaagct ttcttcactt tgttcatgta gatagaagca
     2221 cctactaaaa caactcctaa tccacctatt ccaattacac caaagtaaga tgctaataaa
     2281 acaaacaacc ctactggcca taatccacat aacaacatag ttactaatcc tgctgtcccc
     2341 acatcgaaac ttgctaatgt aaacacatca gtgataattg gtgccaacca tgttgccata
     2401 tataatgttg taacaacata caacgaacat cctactaatg atctcacaat atttccttta
     2461 aaataaggaa tcattaaaca gatggcgaaa gcaaagaatg ctaaatctcc aaaaggtaat
     2521 actttatttc ctggaagaat tagtgctagc aataatgaga ttggtacaag caatagagaa
     2581 gttgacataa tagttggatg acccacagtt aacgctgcat ccattccaat gtttacttgg
     2641 cgaccattta actttttatt cgtaaattct ttcgccgctt ctgcaattgg cattaaacct
     2701 tccataaaca ttgctaccat tttaggcata atcttcatca ctgccgcagt cataattcct
     2761 aagtttccaa ttcctgctac gtcatagcct gccataatac ccactacaat accgataatt
     2821 aggccaataa caactgtgtc acctaaaaca ccgaaacgtt ttgttaatgt ttctgcatct
     2881 gcatctattt tattaaatcc aggaatacga tcaaaaaccc aatttactgg tttggcaaat
     2941 agtactcctg ataatcccat catatgtgtg atagagattc ctggatagcc gaaaaattcg
     3001 ctaacagttt tttgtgtacg atctgctaag aaccattgta aaattactgc gacaatcgcg
     3061 ccaattaagc caaaccaaaa gtttcccgta acagattgag taatcatacc taggaaaatt
     3121 gcgaaccaaa agttccaaat atcaacattc aatgtttttg tccaacccaa aaccacaaat
     3181 atgaagttaa gaattaatga aattggaatc attaaaattc ccaatgatgt agagtaagcc
     3241 aaaggtccac caacacctac gccaatatct aggatattca ggccaccacc gtattgttcc
     3301 cccatttgtt gaattgctgt tcctaaacca tctgataata aacttaaaac taatcctaaa
     3361 ccaatagaac cgataccaac agtaacgccg gaaacaaatg ctttaccagg ttttaatcca
     3421 aataatatcc cgattacaaa aataatcagt ggtaaaaaga cgtttgaccc taatccaata
     3481 aaccattcaa aggcatttaa tacaatatcc atctctctat tcctcctaat aaactcctgc
     3541 agaatgtact aactcaataa atgcttcttt cgtggtacat gcaagtaatt catttacttt
     3601 ttcttcattt tgaaataggc taactaagtt ttgtagtgta tcaatttgtt catgaggttg
     3661 tgacattgcc aacataaaga ctaaacgtac aggtatttca tgagatttat ctgtcatatc
     3721 tgaaaatacc agtggttcct ttaatgaggc aaaacagatt tgagagctat ttacatgtgc
     3781 ggaatctgta tgtgggatag caaacccaat ttgatttact tctaatccag ttggaaattc
     3841 ttgttcacgg ttggtgatac cttctaagaa actatctttc acgcaaccag cgttttttaa
     3901 ttgttcagac attacttgaa acaattcttt ttgatctttc acttctaatt gaaataaaca
     3961 taattcttta tctagataca tttttattct cctttttgtt gaaaaattct tagtaatttt
     4021 tcgctatcat gaacttgtaa caagcgatcg accatttctt tttgcccaat aaattggtaa
     4081 agttcttcat atactcctct aatctcagat acatcttctt cagctaaact aaccataatg
     4141 actaatttga cttttcgatc gccccaatta atcgcatttt ttaatgctac aataaaaatg
     4201 ttggattcaa tgaccattga tggattcgca tgcggtaaag caacaccact ttctaaatta
     4261 gtattcccca ttttctctct agagaagata gaagcacgaa actcttcagt aactaatgaa
     4321 ttggcttcta gttcggaaat catcaaatcc aaacattctt ctttgctttc cacctgtact
     4381 cctgttttta ctaaagatga ttgaacaaat ttagatatgg tgggaacttt aaccgcttta
     4441 ggaatcagtt cattttgaat aaatcgcgaa ggttcttcta ttaaatattt agtataagct
     4501 tccataatat tcatataatc tgttttactt accaatggag atacccttac taagggtata
     4561 ccacctgcat caaaggaaag agaggaaata atcaaatcaa cttccccaat ttcagctaaa
     4621 tgaaacttat ctaaagttga tatttctaca ttatcttttg ctggtaaaaa ccgtcgaact
     4681 ttattgtaaa ttaattgcgc agaagaaata ccgtattggc aaataatgat gatattattt
     4741 gctttggact gatcttcaat agcaatctga aaatgaatca aaattaagga aacttcatcg
     4801 tccgttaaag tcacatcaaa ttcttcttca aggatggaca tggcgtacca tactatgcta
     4861 aagagttctg aatattgaga tttgatattt tctaataacg gattttgaat tttaatacct
     4921 ttttttaaac gaaggaccat tgctggcaca tgatacaata aggattgata taatcgatca
     4981 ttttgagtca aatcaatttt ttcaatctca ctcattcttt caatcaattt atgaacgctc
     5041 atagcgtact cttcattgct ggtttttaaa ttatttgtca cacgatgtgc aaatagttga
     5101 cgacatagat attctttatc tgcgtcataa aatggaagat tcaattttgc cttcaattct
     5161 tcaattaaac catttgccac aatgtacgtt tccatatagc gaatgctatt gaagaggaat
     5221 tcttcttcaa cagttaaatg atgacctttc agtaaacggt tacattggat aactaaagta
     5281 gaaatcaatg accgaacata gtaatcagaa accttttcag tcagttcact gtaatcattg
     5341 aatagcaaat catgaatgac actaataact tttgaatcaa acaacatatt taaaacttga
     5401 aaaaatgttt ttgattccat gtcattcgca taatagaata caagttgctt gattgctcgt
     5461 tgaattgctt gttcattacc agtaaaacta attccttctg cagatgactg caacttaact
     5521 tctccactgc caataatttt attgataatt ctcaggtcat tgtataacga tgttttacta
     5581 accataaaac tttgagacaa atgagttaaa gaaacaggct tatcaccaaa caaaacttct
     5641 ttaatgatct cgacacgtct tttttctgga gaataaatat ctttttcaag ataattttct
     5701 accgatgaaa tcaaatgttc aacgtttttc ctatcaccta tgagtttgat acccaaagaa
     5761 ggtaatcgct caattgttac ttggtaatta actacataat cttccaacaa ttcaatatct
     5821 tgataaatgg tcttggtcga cactgccaat ttatcactaa aaaaagaagc gggtttaaag
     5881 tcttcttgtc gacttaataa ttttaataaa tttacatgtc tttcaatcaa acttgttcac
     5941 ctcttaacgc tagcatttgt tacctctttt cattatttat tctagcactg gaaccccctt
     6001 ccctcaatta catctatgtc aataatactt gtggaagttt gttgtaaagg aaatccaaat
     6061 aatcttaaaa aatgagaaac aaaaaaggag aaatccttaa aagagctaag atattccaat
     6121 agaaaatact ccttattatg gaagtaatat gaaatattac aattgaaaaa taaaaacaat
     6181 ataatggcgt cactaaaatt cgtatttttt tattataata taacttaatt acaaatgctc
     6241 atctatgaac aattgagtcc ta
//
LOCUS       DARPZJ010000099         6202 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.105, whole genome shotgun sequence.
ACCESSION   DARPZJ010000099 DARPZJ010000000
VERSION     DARPZJ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.105"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            191..709
                     /locus_tag="SLE23_002686"
     CDS             191..709
                     /locus_tag="SLE23_002686"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEI8469522.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            837..1520
                     /locus_tag="SLE23_002687"
     CDS             837..1520
                     /locus_tag="SLE23_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEI8469523.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1829..1902
                     /locus_tag="SLE23_002688"
     tRNA            1829..1902
                     /locus_tag="SLE23_002688"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1863..1865,aa:Arg,seq:tct)
     gene            2061..2420
                     /locus_tag="SLE23_002689"
     CDS             2061..2420
                     /locus_tag="SLE23_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HEI8469524.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2543..4174
                     /locus_tag="SLE23_002690"
     CDS             2543..4174
                     /locus_tag="SLE23_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HEI8469525.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4236..4877)
                     /locus_tag="SLE23_002691"
     CDS             complement(4236..4877)
                     /locus_tag="SLE23_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEI8469526.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5063..5139
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5159..5467
                     /gene="rplU"
                     /locus_tag="SLE23_002692"
     CDS             5159..5467
                     /gene="rplU"
                     /locus_tag="SLE23_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEI8469527.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5494..5838
                     /locus_tag="SLE23_002693"
     CDS             5494..5838
                     /locus_tag="SLE23_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEI8469528.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5851..6144
                     /gene="rpmA"
                     /locus_tag="SLE23_002694"
     CDS             5851..6144
                     /gene="rpmA"
                     /locus_tag="SLE23_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEI8469529.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1951 a         1023 c         1313 g         1915 t
ORIGIN      
        1 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
       61 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
      121 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
      181 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
      241 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
      301 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
      361 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
      421 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
      481 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
      541 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
      601 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
      661 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
      721 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
      781 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
      841 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
      901 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
      961 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
     1021 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
     1081 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
     1141 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
     1201 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
     1261 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
     1321 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
     1381 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
     1441 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
     1501 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
     1561 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
     1621 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
     1681 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
     1741 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
     1801 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
     1861 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
     1921 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
     1981 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
     2041 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
     2101 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
     2161 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
     2221 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
     2281 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
     2341 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
     2401 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
     2461 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
     2521 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
     2581 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
     2641 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
     2701 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
     2761 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
     2821 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
     2881 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
     2941 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
     3001 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
     3061 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
     3121 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
     3181 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
     3241 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
     3301 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
     3361 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
     3421 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
     3481 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
     3541 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
     3601 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
     3661 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
     3721 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
     3781 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
     3841 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
     3901 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
     3961 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
     4021 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
     4081 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
     4141 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
     4201 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
     4261 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
     4321 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
     4381 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
     4441 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggctgg
     4501 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
     4561 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
     4621 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
     4681 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
     4741 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
     4801 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
     4861 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
     4921 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
     4981 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
     5041 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
     5101 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
     5161 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
     5221 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
     5281 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
     5341 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
     5401 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
     5461 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
     5521 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
     5581 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
     5641 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
     5701 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
     5761 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
     5821 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
     5881 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
     5941 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
     6001 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
     6061 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
     6121 tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt gacaagactt
     6181 ttgtcacagc cttttttgtt ta
//
LOCUS       DARPZJ010000100         6135 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.106, whole genome shotgun sequence.
ACCESSION   DARPZJ010000100 DARPZJ010000000
VERSION     DARPZJ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.106"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(207..1169)
                     /locus_tag="SLE23_002695"
     CDS             complement(207..1169)
                     /locus_tag="SLE23_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEI8469530.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="SLE23_002696"
     CDS             complement(1171..2610)
                     /locus_tag="SLE23_002696"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEI8469531.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="SLE23_002697"
     CDS             2795..4741
                     /locus_tag="SLE23_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEI8469532.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="SLE23_002698"
     CDS             5005..5877
                     /locus_tag="SLE23_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEI8469533.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1947 a         1054 c         1083 g         2051 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttaatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttctt
//
LOCUS       DARPZJ010000101         5878 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.107, whole genome shotgun sequence.
ACCESSION   DARPZJ010000101 DARPZJ010000000
VERSION     DARPZJ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.107"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            642..1376
                     /locus_tag="SLE23_002699"
     CDS             642..1376
                     /locus_tag="SLE23_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8469534.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1392..2561
                     /locus_tag="SLE23_002700"
     CDS             1392..2561
                     /locus_tag="SLE23_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8469535.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2577..3572
                     /gene="lacD"
                     /locus_tag="SLE23_002701"
     CDS             2577..3572
                     /gene="lacD"
                     /locus_tag="SLE23_002701"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEI8469536.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3651..4577
                     /locus_tag="SLE23_002702"
     CDS             3651..4577
                     /locus_tag="SLE23_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEI8469537.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4596..5846
                     /locus_tag="SLE23_002703"
     CDS             4596..5846
                     /locus_tag="SLE23_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8469538.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1968 a          955 c         1204 g         1751 t
ORIGIN      
        1 agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt gactaaacga
       61 agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat tcagataaac
      121 tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc ttaagagaga
      181 acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat ttattctcat
      241 agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga tttgaaacca
      301 aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca ctggtaagta
      361 gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta aaaaaagata
      421 ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa aagttggaaa
      481 attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat attaacaaga
      541 ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa ataccactac
      601 tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat acctttcaat
      661 caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa aacagtatgg
      721 tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc gttagtcgca
      781 cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat cgacaacatg
      841 gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct ggcgcatata
      901 gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata ttggccttca
      961 agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta ggtgagcctt
     1021 tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc gagaaatcct
     1081 atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg aaacctttat
     1141 ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag gaattttatg
     1201 ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga tcaccagtgc
     1261 tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt acattaagtg
     1321 tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact aactgaattg
     1381 gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga gcagaaaata
     1441 ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac cgttatcaag
     1501 aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct ggagagcgac
     1561 caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat acactaattc
     1621 cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt ggttcgaccg
     1681 atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc ttggtctcat
     1741 ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc aatcagctgg
     1801 tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg gctacacaaa
     1861 tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat gacgctggtt
     1921 ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt tttgatcaag
     1981 caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga gaagaagtca
     2041 tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc atcatttact
     2101 taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt ctcgagttaa
     2161 ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat ggtcccaaat
     2221 cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca tatacgcaga
     2281 aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa cgcgttgttg
     2341 gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt gcagattcgt
     2401 tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg atcgcattac
     2461 tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga acagtcaatc
     2521 gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg tgaagcatgt
     2581 tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca gaaggcatta
     2641 ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg gctttaggga
     2701 tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa gaattgactc
     2761 cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca cagaagcgtg
     2821 cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa accgtacccg
     2881 gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag ttaggtgcgg
     2941 atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc aatcggcaaa
     3001 agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg ccattttatt
     3061 tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc tatgccaaag
     3121 caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag tataaagtag
     3181 atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat gcaacagggg
     3241 agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc gatgcaacag
     3301 atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg gagacattgc
     3361 gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga gcaacttgga
     3421 aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa tggctgacag
     3481 aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact gccatcccat
     3541 ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt agtgataaga
     3601 gatatgtgtg attataattt atcattattg aaactgggag gatattttat atgaataaaa
     3661 gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa ttaaagcagg
     3721 caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt agctgtcctt
     3781 acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct gatttaattt
     3841 tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta actctaaaag
     3901 agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta aatttagaac
     3961 ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt ggtagaatcg
     4021 tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt tgtttaactg
     4081 gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca ttatccaaat
     4141 caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt gatgaaccaa
     4201 ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt ttattagttc
     4261 ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc gttgattata
     4321 taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta acggctaatg
     4381 gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta gcatcaaaag
     4441 catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt cttccagaaa
     4501 atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt atgttaggaa
     4561 aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt caaaaaatag
     4621 ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg gctgcagtta
     4681 tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg atagaaggat
     4741 ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca tcagattcaa
     4801 catttggtat tattggatta gctgttacct actctttggg acacaatcta gcaaagactt
     4861 atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt ttacttacac
     4921 ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt acctcgggtc
     4981 tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg tttgtactta
     5041 aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga gctttcgttg
     5101 ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta atttgttata
     5161 aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa ccactatctt
     5221 tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt ttcttttgga
     5281 tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta ttattgcaaa
     5341 actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac attataactt
     5401 atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt gcacttgcca
     5461 ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag ttatcaatcg
     5521 ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact atattaaata
     5581 taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt acttattttt
     5641 caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg acaactccac
     5701 cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg attcaagtaa
     5761 taacaattgc aataaatgtt ttgatatact atccattctt taaattagat gataatgcca
     5821 agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt agttaagt
//
LOCUS       DARPZJ010000102         5650 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.108, whole genome shotgun sequence.
ACCESSION   DARPZJ010000102 DARPZJ010000000
VERSION     DARPZJ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.108"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            4..2376
                     /locus_tag="SLE23_002704"
     CDS             4..2376
                     /locus_tag="SLE23_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469539.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="SLE23_002705"
     CDS             2437..3897
                     /locus_tag="SLE23_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEI8469540.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..>5650
                     /gene="topB"
                     /locus_tag="SLE23_002706"
     CDS             3908..>5650
                     /gene="topB"
                     /locus_tag="SLE23_002706"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEI8469541.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKI"
BASE COUNT         2160 a          951 c         1228 g         1311 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgct tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaga agatgtttga acaccagaga
      121 aagaccaacg gtcagccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcggc
      301 ctggatatga caatcgaaaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc agaaaaagga aaagaaaatc ttcttcctga agtacaagca
      481 attattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 gactatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctttgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgaa
      961 aaggaacaaa aacaaacggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taagcaagaa
     1081 gtcaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtgaaag aacttttgaa ttttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc tgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacggggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac ttcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagcg
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaaca tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaatg agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagttaaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac taaatcgtga tcagttaaac
     3181 gatacgtggt tagtttcgat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagttgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aagtcattta tgaagaagtc gcaaaagaag aaaagatcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaatt ggtttccgct
     3541 cacaaagtaa atgcgtcttt tggtcagcag ctttctgtta acgattcaat agaagctatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagcttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc tcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggattg gaatgatcaa ttgaagcatg aaatctacca acaagagatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggtagac agcaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaaaccgtca caagcgaagg cttatgccga
     3961 tagcttttct aaagctaccc gaaaagatgg gtattttgag atccaagatc gattgttttc
     4021 aggagaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agagcatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatagcttg
     4261 gacgatcatt caacaagcag gcgccgatca tggaaagata tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagatg cagaagagac
     4381 ctacccaaaa tttgaagaag cacaagcacg ccagatcgcc gattggttga tcggcatgaa
     4441 cggtagcccg ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gtttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttacaggaaa agattagaaa
     4561 cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggtacg atccaccaag ttgaaaccga
     4741 gaaaaaaagt gcggcaagtc cacgtctttt ttctctatcc agccttcaat ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt tgtatgaagg
     4861 gaaatatcta agctacccac gaacagatac cccttatatt acagaagggg agtatgcgta
     4921 tctgttggat cacttagacg aatacaaaca ctttttaaag gccgaagcca ttcctactcc
     4981 tattcataca ccgaatagtc gatatgtgaa taataagaaa gtccaggaac attacgcgat
     5041 cattcctaca aagacggtca tgacggcagc ggcttttgaa caattaagtc cactgcagca
     5101 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     5161 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ctaaagacag tcggaaaagt
     5221 accagtagat ctaggttgga aaaagctgtt tggcaaagag agcgacagaa aagaaaagga
     5281 agaagaaccg ctacttccta aagtgacaaa aggagaagcg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaacgaagc caccacaacc ttataccgaa ggtacgttga tcacagcgat
     5401 gaaaacagct ggaaaaaccg tggatagcga agaagcacaa tccatattga aagaagtaga
     5461 aggaatcggt acagaagcaa cacgagcaaa tattattgaa actttgaaac aaaaggaata
     5521 tatcaaggta gaaaaaaata agcttgtggt gacaaataaa gggattttac tttgccaagc
     5581 cgtggaaaaa gagccgctgc taacaagtgc cgaaatgacc gccaaatggg aaagttactt
     5641 attaaagatt
//
LOCUS       DARPZJ010000103         5501 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.109, whole genome shotgun sequence.
ACCESSION   DARPZJ010000103 DARPZJ010000000
VERSION     DARPZJ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.109"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            153..1142
                     /locus_tag="SLE23_002707"
     CDS             153..1142
                     /locus_tag="SLE23_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEI8469542.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1124..1585
                     /locus_tag="SLE23_002708"
     CDS             1124..1585
                     /locus_tag="SLE23_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEI8469543.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1635..2099
                     /locus_tag="SLE23_002709"
     CDS             1635..2099
                     /locus_tag="SLE23_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEI8469544.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2113..2862
                     /locus_tag="SLE23_002710"
     CDS             2113..2862
                     /locus_tag="SLE23_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEI8469545.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2862..3692
                     /locus_tag="SLE23_002711"
     CDS             2862..3692
                     /locus_tag="SLE23_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEI8469546.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3692..4339
                     /locus_tag="SLE23_002712"
     CDS             3692..4339
                     /locus_tag="SLE23_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEI8469547.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4437..5213)
                     /locus_tag="SLE23_002713"
     CDS             complement(4437..5213)
                     /locus_tag="SLE23_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEI8469548.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5295..5438
                     /locus_tag="SLE23_002714"
                     /pseudo
     CDS             5295..5438
                     /locus_tag="SLE23_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1882 a          747 c          979 g         1893 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctggcatttt attatataaa attgttataa
       61 aaaatttttt ttgaaaaata gtattgcaaa ataaagcaat ttcatagata ataggtatcg
      121 taaagttata taactttata atacctatta gagtgaggga taaagaaatg agacaactac
      181 acaaagaaca gattgaaaca gcaatggcag cgttaaagga aaagacaatt gatcatgtat
      241 attttacagc atgtgggggt tcacaagccg ttttaatggc tggtcaatat ctatttgata
      301 aagaattaac tgtaccttgt catgtttata ctgctaacga atttaactat gctataccaa
      361 aaggattatc tgaaaattct ttagttatca cttgttccca ttctggcaca acaccagaaa
      421 ctgtagaagc aacaaaaaaa gcaagagaat ttggagcaat gactatttgt ttatctaatg
      481 aagaaggatc tcctctatgg gaagcagctg aatatcctgt tcactatgat tggggtaaag
      541 atgttgatgc tagtgattta aataaaggaa ttctttatgg tttattattt aatattttac
      601 ttgttttaga tggctctaaa aaatgggaaa cttgcttgaa tgaatttgat aagttaaatg
      661 atcttgttat tgctgaaaag agcaaatttg aaataactgc taaagaatgg ggtaaaaacc
      721 aaaaacgaga taaaattatt tacacaattg gtagcggtat taattacgga gaaatttact
      781 ccacagcagc ttgctggttc atggaaatgc aatggattaa ttctaatgct attcattctg
      841 gggaattttt ccatggtcct tttgaaatca ctgattatga tgtaccattc atcttagtga
      901 aaagtattgg agatacaaga tttttagatc aacgggtaga agacttcact aaaaaattca
      961 gtaataaatt aatggtttta gaccaagctg attttgactt agaatctata gatagtgtag
     1021 cgaaagaata tattgcagct gtacttagtg gcgttgttat tcgccaaatg gtagaagcga
     1081 ttgcttttga aagaggccat tccttagatg ttagacgcta tatgtggcaa atgaaatatt
     1141 aattaatagg aggttgcaaa agatggcaaa tcaattattt cacattgtga ttacaacaca
     1201 ttctaccctt tgtgagggtt atttaaaggc aacaaaatta attttaatga atgacgccac
     1261 aggtattagt gctgttccat ttaaagaaaa tactagtcca gatgattttg aggagagtat
     1321 gaaagaaata attagtcagc atcatttgca acctctaatt attttaacgg atttaattgg
     1381 aggaacacct aataatgttt ctattaaaca gttgaacaac aatagaattc aaattattgc
     1441 tgggattaat ttacctcttt tactggagtt attaatggcc cagtcagctg gtaaatctat
     1501 agaagaaata gattttaagg aattactgaa taactctcaa aaaagtatgg ttcatattaa
     1561 ttcgctttta aaagatgtca gttaaggtgg caatttctat tctataaatt ttaaaaattg
     1621 aaggaggaaa tagaatgatt aaattagtgc gtgtagacca cagattactt catggacaag
     1681 taatattttc ttggactaaa cagtatgata ttaaccatat tattgtggct gataacaaag
     1741 ttccaggaga tccaatgtct gtgatggctt tgacaattgc taaacctgct gattgcaaat
     1801 tagacattgt taaaattagt gatgttaaag ggattatgga aacatcccca aatgataatt
     1861 acatgatttt aattaaagga cctaaggaag cttttgaatt agttcaaaat ttaccagaaa
     1921 ttaaagaaat taattttggc ggtgtgtcta agaaaagcga gtccaaacaa tatggaaagg
     1981 cagtcttttt aactcctgaa gaattagaag ccacaaaaaa aattcttgat caagaagtga
     2041 aaatatttgt gcaacaagtc ccatcttcaa gtattgaaaa tgtagatttt agtaagtaag
     2101 gggggaaaat aaatgttatt aaaagccatt ttattaggtt tagttggtgt ggtagctgtt
     2161 attgactcca ggttaattgg tcgacaaaat attggtagac cactaatttt gagtacactt
     2221 gccggacttg tgctaggtga cttgcataca gggattgttc ttggggcatc tttagaatta
     2281 atttctatgg gattcgtctc aattggggcg gctggacctc ctaatatgca acttggtagt
     2341 attattgcca ctgcttttgc aattttaact aatagtagta cagaaacagc cttaacaata
     2401 gctatcccag tggctgtagc tggtgaattt atgagtatta tcatgcgtat gataattgct
     2461 caatttggac atgctgcaga taaagccatt gaaaataata aatttagaaa agctcaaatt
     2521 attcatattt attggtcatt tatttttaat gcttttgttt actttattcc aatcttttta
     2581 acagtatatt ttggtgctga cgttgtggca gatttagtag ataaaattcc agaaatgatt
     2641 acagacgcct tgactgtctc tggaaatatg ctttccgcat tagggtttgc aatgctatta
     2701 agcacaatgt tgagtaaaaa attatatcct tactttattt ttggattctt tattgttgcc
     2761 tattcaggtc tttcactaat tggcgtgaca atttttgcag ctctgattgc ctttgtaatg
     2821 gatcaagtta aatatggaaa aagagaagag gcgcatggtt aatggaaaat agtacagaaa
     2881 aaaaacgttt aatcacaaaa aaagatcttc ataagatgtg tcttcgttca tggacaatca
     2941 tgtgttcgtg gaattatgaa agacaaatgc atatgggatt tatgtatggg atggcgccaa
     3001 ttttaaataa agtttataaa aatgatgaag agaaaaaaag agaagcttat actcgtcata
     3061 tggcattttt taactgtacg cctcaaatga ctccatttat tatgggactt tgtgcttcta
     3121 tggaagaaca aaatgctcaa gcagaagaag gaaactttaa tactgaatct atctccatga
     3181 ttaaaaccag tttaatgggt ccttttgctg gaattggtga ttcatttttc caaggtactt
     3241 taagaattat tacatttggg attggattgt cttttgctaa gcaaggtagt attttaggac
     3301 cgattttagc tgttggcctt tttgctatac cttctatttt agctgttttt tacggcggta
     3361 aattaggata tgagtctggc aataaatacc ttactaaatt gtatcaagaa ggtcttatgg
     3421 atcgagtaat gcaatttgct tctatcattg gtttggctgt agtaggtgga atggtggcta
     3481 gcatggtgcc aattgtcacc cctttaaaat tcactacagg gggaacagaa cttgttttac
     3541 aagacttact tgattccatt attcctggat tattaccact tgtatgtact ttgggaatat
     3601 ataaattgat taagaaaaat gttagtacaa atatgctctt attaggttgt attttggcag
     3661 ggtttgtttt aagtataata ggtatcttat aatgattaag gctctaattt ttgatatgga
     3721 cggagtttta attgatagcg agattatgta tcaaaagtgg gtatttaatt ttttaaaaca
     3781 agaaaattta agctatcctt tgtattctta tcaaaaaaag attggaacta cagcaagtat
     3841 ttttgatgat atagaaaagt acaatgaggg atgtaacagt ttagaattga agggaaaatt
     3901 tactaaatat tggaaatcgc aaaagattga ttacttggat atttttccta atatactaat
     3961 tgaacagctt gaatggttaa aaaagaaaaa aataaaaatg gcaattgctt cttccagtcc
     4021 aatggatact ataaatgaag ttgttaccac ttgtaaaata gagtcatatt ttgattgttt
     4081 aattagcgga agagatttgc cagaaagtaa acctaatcct actatattcc ttaaagcttc
     4141 agaacagctc agaattccag ttgaagaatg tctggtgata gaagattctt ataatggtat
     4201 aaaagctggt aaaagagcaa atatgaaggt tcttgcaatt aaagataaac gtttttctca
     4261 agatgtaagt ctagcagatg atgttattta cgatattaaa tatctgcgac aagaagtaca
     4321 ggtgaaattt ggaatataaa taagtttttt gatgtattta gagaatatta gtaaaaataa
     4381 aaatcatgcc caaatctaat caaaattgat tgctttgggt atgatttctt ttaatatcaa
     4441 tctattactt taggatctga atcattttta tgcaccgtat ctaaagtgat attttctgtg
     4501 acttcaataa cataactaat tctatcacaa cgaactgtgg attgagaata atgaaatggt
     4561 tgattatttt tatctttgcc aaccttttct aaaataaata gcggatctcc tactatacat
     4621 tgcaataagt cggaaagctc aggtgttgca gataaaccgt ttatttccat aatagagctc
     4681 gtagctttga catcatagtc atcttctaga agtttatata atgaagtata ttggctacct
     4741 ttttcaaata aagttggaaa tttttcttct gatgcgaaaa aattatcaat tcccatcggg
     4801 gcaccgtctt cccacattaa acgtttaata ttgtaaactc tatcagttac attgatttgt
     4861 aatttattag ctaaaaactc atcagccttt ataattttag aatgtaaaac agtatatcta
     4921 attttatgtc ctcgggtaga aagagaatcg ctaaatccat gaactccagc taattttaaa
     4981 ctttcttttt tttgagttac aaaggtccct ttccccctta atcgttcaac tgttccactt
     5041 tctgttaaaa gtttaaaagc ttttcgaatg gtaatcttac ttactccata aattttacat
     5101 aattcttctt ctgtaggtaa ttgctctcct ggaagatatt ttttttcacg aatatcgtta
     5161 cgtatagaag cttctacttg tagatataat ggtctattat cttgaaaatt catagtacac
     5221 tccctaaaaa gttatacttc attatatcac aatttattaa aataaaagat taagatataa
     5281 atataaatga actagtcttt gactaaccaa tgcccgcttt tgaaagaaaa caaattcatt
     5341 ctgttttaag taaaaatcct tatgttacca ctcattctga aggggatgag ccttatcgct
     5401 acttggttgt ggaaccaagc gataagacaa ttttataaat tcaatattaa ttaaaataaa
     5461 aacaaacaaa gtagattatt ttactttgtt tgttttttta t
//
LOCUS       DARPZJ010000104         5347 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.110, whole genome shotgun sequence.
ACCESSION   DARPZJ010000104 DARPZJ010000000
VERSION     DARPZJ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.110"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..376
                     /locus_tag="SLE23_002715"
     CDS             <1..376
                     /locus_tag="SLE23_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HEI8469549.1"
                     /translation="WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLK
                     EYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTR
                     KEGTLFGFSVCTEIKVLLGIPA"
     gene            471..1022
                     /locus_tag="SLE23_002716"
     CDS             471..1022
                     /locus_tag="SLE23_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HEI8469550.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1698..1952
                     /locus_tag="SLE23_002717"
                     /pseudo
     CDS             1698..1952
                     /locus_tag="SLE23_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            2022..2534
                     /locus_tag="SLE23_002718"
     CDS             2022..2534
                     /locus_tag="SLE23_002718"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8469551.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2531..3568
                     /locus_tag="SLE23_002719"
     CDS             2531..3568
                     /locus_tag="SLE23_002719"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEI8469552.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
     gene            3728..3904
                     /locus_tag="SLE23_002720"
                     /pseudo
     CDS             3728..3904
                     /locus_tag="SLE23_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            3959..5269
                     /locus_tag="SLE23_002721"
                     /pseudo
     CDS             3959..5269
                     /locus_tag="SLE23_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
BASE COUNT         2037 a          790 c         1017 g         1503 t
ORIGIN      
        1 ttggttacgt aaaaaacggg acacacaagc agcctatgct tttcttaagc ggttagtgaa
       61 gcagtttgat gaaccgaagg ttgtagtcac agataaagcc ccctctatta caagtgcctt
      121 taagaaacta aaagaatacg gcttttatca agggacagaa catcgtacca ttaaatacct
      181 gaataatttg attgaacaag accatcgtcc agtaaagaga cgcaataaat tctatcgaag
      241 tttacgcact gcctctacca cgattaaagg catggaagcc attcgaggat tatataagaa
      301 aacccggaaa gaaggcactc tcttcgggtt ttcggtctgt actgaaatca aggtattatt
      361 gggaatccca gcttaaatca tagataccgt aagggatttt attctttatt taaaactttg
      421 caacagaacc gaagagcgag caagacagga acgagagaac aaacatactc atgaaaagac
      481 tagaggcttc gacctcgaac tttaataata agttagatgt ttttgaagaa aagactaagc
      541 atgcaagatt aaactttgaa acaactgcaa agcactatat taaacgactt gatgaagata
      601 atttgaaatt agattttcaa caagctattc aagatgaatt aagcgatact aaagacgaaa
      661 tacgtgaagt gacgaaacaa gcgagagaag aaacaaaaga gtataaagaa atcttagaaa
      721 gtaaaataaa agaccataac aaagtggttg ataaatcgaa tacagcgcta aaagtgatga
      781 caaaaggcgt tacaaatata ttttttgtgc taattatttt tgtacttgta atgcttgtga
      841 caggtccgat aggtcatttc tttggtattg aacatttata tagctttatt aatggtttta
      901 ttgatgacca cgaaagtgca tggcgatatt tgatgttgat actttatgca gtaccctatg
      961 tattcttcgc tatcattctg tggctcatag cattgttttt tagagtattt aatgaccttt
     1021 aggtagattt atatataaaa agggctaaat acgcaaaata cccccttaaa atgcaaaata
     1081 aatgcaaata agggggtaac tccttatgaa aaaacaacta atagtattat aacacgtttt
     1141 tatgccgaga aaacttattg gttggaatgg gctatgtgtt agctaacttg ttagcgagtt
     1201 ggttggactt gaattgggat taatcccaag aaagtaccaa ctcaacaaca cataaagccc
     1261 tgtaggttcc gaccaataag gaaattggaa taaagcaacg aaaggagttg agtaaaatga
     1321 gtgagaaaac gaagaaaatc attcgagtat cattagcttt ttcacaagta gtagtgcaat
     1381 cattgatagt ttattatact taccagcaat ataaattatc taaagagaat taagttttga
     1441 ttatgtaata agttttggta ctaaaaaaga cttgatctaa ttagaccaag tcttttgtta
     1501 gtgttatatt aataacaaaa taaaaataag aagtcgctca ctccccgacc aaagtttgtg
     1561 agcaaaataa acagtcgatg tttgtttctt aattgtatat cttgatatta aacgatttaa
     1621 gattattctt caagatatat attcgcaaat gtaattggaa aagcgacttc ttaaacaaaa
     1681 ttaaggagtc gctttttatg gcaaaaataa cgaaaaatga gcaagaaaat ttggtggaaa
     1741 attacacaaa aaaaccggcg tactctaata gccggttaga cgcacatttc gtgtgcactt
     1801 ctaatccgaa attgagcttt gacgctatga cgatagtcgg aaaccttaat aaaaacagcg
     1861 ctaaaaagct atccgatttt atgagtttag atccacaaat tagactttgg gatatacttc
     1921 aaacaaaatt taaagctaaa gcactacaag accccctatg ttaggctagt tgtcgtatag
     1981 gataataagt tataataaag actatacgga ggatgattac catgacaaat aaaaacaatg
     2041 aacgttactc taccgaactg aaagcgacag ccatcaagaa aatgatgcca cccgaaaata
     2101 gggggattcg ccaattaagt caaactttgg gcattccaga agcgactctt tgttcttggc
     2161 gtaaaaaagc tagaattcaa gggaatacta cacccggaac gaaaaaaaat gtcgaaaaat
     2221 ggtcaagtga agataaattt ttaattgtga tggaatcatt ctcaatgaac caagtagaac
     2281 ttgcggaata ttgccgaaag aagggcttat ttaaagaaca aattgaggct tggaagaaaa
     2341 cgtgcttatc tgcgaatgaa caggaagaaa atcgaacgag agaacttgca actgaactaa
     2401 aagaagagaa aaaacaagcg cgtcaattag agaaagaatt acgtcataag gaaaaagcat
     2461 tagcggaagc cgctgctctc ttattactaa gaaaaaaagc acacgcgatt tggggggacc
     2521 aagaggaaga atgatttcat cttcagatcg caaacaagct gttgaactta ttcaagaagc
     2581 caatcgcaat ggggcccgtc tcacctatgc ctgtaatgag ctgaatatta gcgttcgaac
     2641 ctacgaacga tggacgcgtg aaggtacgat agcgcatgat caacgccctt tggcgaaacg
     2701 tcctgtaccc aaaaataaac tgacggatca agaacgcgaa aaaataatag aaaccgtttc
     2761 aaaaaaagaa tttatgaatt tgccacctag ccaaattgta ccaaaacttg cggattgctc
     2821 gatttatatt gcatcagagt ctagcttcta tcgtgtattg cgagaaaaaa atatgcaaca
     2881 tcaccgtggc cgaagtcaag tttcacaaaa acgcataccg ccaagtcacc ttgcgacgaa
     2941 gccaaatgaa gtttggactt gggatattac ttggctaaaa ggtccaataa aaggactctt
     3001 ttaccggtta tatctcatca ttgatttatt tagccgtaaa atggtaggct gggagatttg
     3061 ggaatcagaa gaagctcgtc atgccgaaaa acttattaaa cagacggtgc ttaaggaacg
     3121 tatccaagga cagccgttgg ttttacactc cgataatggc agccctatga aagccgcgac
     3181 ttttcaagtc ttactcgaaa aattaggaat tcaaagttct tattcaagac cacgagtgag
     3241 taatgacaat ccttattcgg aagcggcttt ccgaacgtta aaatatcgac cagaatatcc
     3301 caataacggc tttaaaacaa tagatgatgc tcgaaaatgg acgaaagagt ttgtcgattg
     3361 gtataacgat tctcatttgc atagtgggat tcaatttgtg tctcctgcag cgtgtcatga
     3421 aggacgacat ctcgctattt tagagaaacg aaagcaggtt tacgaggacg ctaaaaagcg
     3481 ccatcctgaa cgctggtcaa aaggtgttcg aaattggact ccacatcaat cggtggcgtt
     3541 gaatccttta aaagaaacag aaagttaaca ggagcataat ctttcaagat tatcaaataa
     3601 ccctcgtcac ccaatagggg aaaaagttat tcttccccta ttggataacg aggccaaccg
     3661 accataggga ggttctgctt tttgataggt ggaaaataaa aatacgacaa ctatattgac
     3721 aaacaccgac catcgtccag taaagagacg caataaattc tatcgaagtt tacgcactgc
     3781 ctctacaacg attaaaggca tggaagccat ccgaggatta tataagaaaa cccgaaaaga
     3841 aggcactctc ttcgggtttt cggtctgtac tgaaatcaag gtattattgg gaatcccagc
     3901 ttaaatcata gataccgtaa gggattttat tctttattta aaactttgca acagaaccga
     3961 atcattaaaa aaacattata cagagccttg ggaagatgaa gtttttagag taattattga
     4021 atataacaat gttcctattg gatatggaca aatatataaa atgtatgatg agttatatac
     4081 tgattatcat tatccaaaaa ctgatgagat agtctatggt atggatcaat ttataggaga
     4141 gccaaattat tggagtaaag gaattggtac aagatatatt aaattgattt ttgaattttt
     4201 gaaaaaagaa agaaatgcta atgcagttat tttagaccct cataaaaata atccaagagc
     4261 aataagggca taccaaaaat ctggttttag aattattgaa gatttgccag aacatgaatt
     4321 acacgagggc aaaaaagaag attgttattt aatggaatat agatatgatg ataatgccac
     4381 aaatgttaag gcaatgaaat atttaattga gcattacttt gataatttca aagtagatag
     4441 tattgaaata atcggtagtg gttatgatag tgtggcatat ttagttaata atgaatacat
     4501 ttttaaaaca aaatttagta ctaataagaa aaaaggttat gcaaaagaaa aagcaatata
     4561 taatttttta aatacaaatt tagaaactaa tgtaaaaatt cctaatattg aatattcgta
     4621 tattagtgat gaattatcta tactaggtta taaagaaatt aaaggaactt ttttaacacc
     4681 agaaatttat tctactatgt cagaagaaga acaaaatttg ttaaaacgag atattgccag
     4741 ttttttaaga caaatgcacg gtttagatta tacagatatt agtgaatgta ctattgataa
     4801 taaacaaaat gtattagaag agtatatatt gttgcgtgaa actatttata atgatttaac
     4861 tgatatagaa aaagattata tagaaagttt tatggaaaga ctaaatgcaa caacagtttt
     4921 tgagggtaaa aagtgtttat gccataatga ttttagttgt aatcatctat tgttagatgg
     4981 caataataga ttaactggaa taattgattt tggagattct ggaattatag atgaatattg
     5041 tgattttata tacttacttg aagatagtga agaagaaata ggaacaaatt ttggagaaga
     5101 tatattaaga atgtatggaa atatagatat tgagaaagca aaagaatatc aagatatagt
     5161 tgaagaatat tatcctattg aaactattgt ttatggaatt aaaaatatta aacaggaatt
     5221 tatcgaaaat ggtagaaaag aaatttataa aaggacttat aaagattgat tatataatat
     5281 atgaaaagct attataaaag acattagtat taaatagttt aaaaaaatga aaaataataa
     5341 aggaagt
//
LOCUS       DARPZJ010000105         5336 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.111, whole genome shotgun sequence.
ACCESSION   DARPZJ010000105 DARPZJ010000000
VERSION     DARPZJ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.111"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(59..277)
                     /locus_tag="SLE23_002722"
                     /pseudo
     CDS             complement(59..277)
                     /locus_tag="SLE23_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(543..737)
                     /locus_tag="SLE23_002723"
     CDS             complement(543..737)
                     /locus_tag="SLE23_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469553.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(837..923)
                     /locus_tag="SLE23_002724"
                     /pseudo
     CDS             complement(837..923)
                     /locus_tag="SLE23_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2089..3129
                     /locus_tag="SLE23_002725"
     CDS             2089..3129
                     /locus_tag="SLE23_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8469554.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            3953..4285
                     /locus_tag="SLE23_002726"
     CDS             3953..4285
                     /locus_tag="SLE23_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEI8469555.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4904..5245
                     /locus_tag="SLE23_002727"
     CDS             4904..5245
                     /locus_tag="SLE23_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HEI8469556.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1941 a          728 c          899 g         1768 t
ORIGIN      
        1 gtatttttat tatatataga tttaacatat gtcggtcggt tgattgatat agctaaagtt
       61 ataactcaac cgaagccgat tcatctacac gaataaagtt gcgagtgttc tcggctaatt
      121 cataaaaatt gttatgtgtt ccatatagca atactggaat aactttattt tcttgaatct
      181 cataagcaac tctatacacg gtgaccgcat acttaaatcc attagaccaa ttacctgata
      241 aacctccagt tttttgctct tacttaaatg gatcaatggc aatttcatca caaacctata
      301 gaggatgagt gacttctgcc taattacgtt aaaaaatatt gaaagtaact ctatgtagca
      361 aaaaatatct agaatttcat ttcctcaaaa ctgatcgata ttgtatctaa aaatatatac
      421 tacctaaaat aggtagtata tattaaaata tgtgcttttg ttagaaaaat caatacataa
      481 attatcatat ctgtatatgt catttaggta tttcagttat gttataatag ttttgctgtc
      541 tgctaccccg gcctaatctg gcaaggggag gaggagatat aatgaaatac ctttttgatt
      601 ttgtttttgc aatcaagcca cttgcagatg tagtgtgcag ttacctctgc aaatggcttg
      661 attgcaaaat tgccaaaaaa gacagtaagc ctacccgtta attctataat atagaaacgt
      721 aaaaaaaacc ccatcagcct gcacgctgat ggggtttggt gatataatga aatacctctt
      781 tgttactcat aattgtacca taattagtca cgaatgcaac caatagaaaa aactacttag
      841 aacggtagat catcgctaat aacaatgcat tgtccaccaa atggattttg tgaagcatta
      901 aatacattgt tattaattgt cgctgctttt aactaggcct ctccccttct attataaaag
      961 aagatatata tcatttctta attacctact accttaaacc aaaatttaag tactacctaa
     1021 tttaagtatt acttaaacaa tctaaaaaat agttatccca attgttatgc ttttataata
     1081 cgattatttg taacaaaatg aatattatat aattaaacac taccatattt aggtagtgtt
     1141 taattattag caaaacaaaa aatatttatt ctattctctt aacttcaact aagttatgct
     1201 gcacaccttt atataaatca tatgcaactc attagctaga caaactacaa gcatgtagtt
     1261 ttatctgtta attatgtact acctaaataa agtagtttat aattagcaag tatatatatt
     1321 taaaaattta agattaattt ttttatgact tgtacaaatt tatctgatat tctcttatta
     1381 agaactacct aatttgggta gttcttattt tttacatttt aagtagtatt taattgcaat
     1441 ttggtagtat ttttttatta tcttattctt agaacggtag tacttaatat aaatataggt
     1501 agtatctaat ttaagtatta atggtagtat ctaaattaac aggtagtatg taactacttt
     1561 aaagtaattt ttttcagatt aacacagtag tatcttatta aataagttaa ttttaatggt
     1621 agtacataat tattatatat atctgacatt ggtagtactt attgtatttt ttagtagtat
     1681 ataatctatt gttttctagc ctaaagcctt gtcttataag aataatataa tatatactac
     1741 tgaaataagg tagtatatat tactagtaat ggtagtatgt tttatatgca taaggtagtt
     1801 cttaatttat tttttgtttt gacactggta gtacttaatt atctttaatt ttaaaactaa
     1861 attttattca tacgtttttc tggtagtatt taattataaa taatatttat ttaaagtagt
     1921 tcttaatgac tttaaaggta gtacataatt cattttattt ctgattttag gtagtattta
     1981 attaaaaaac agttttaatg cgtttgcatt ttttatttat ctttgctatt ttcgaaaaga
     2041 gtaggtaatt ttacataaat aaaacaacgt gaaagtagag gatctacaat gactgatttt
     2101 aaatttttta aggcggatag agtttacaac gaattatttt atcaatttcc aaaagtcttt
     2161 attgtttctg acgaatacaa aaaaatgaaa gattcaacta agattgccta tatgctttta
     2221 aaagcaagat tagagatcgc aatcagcaaa cggcaaatcg atgaagaagg taatgtttat
     2281 tttacttata cgacaaatga actatgtaga gtattaaact gccaaaaaca aaaagcgata
     2341 gcaatcaaaa aagagttgga atcctttggt ttattattac aaaagcagat gggatttaac
     2401 aaacagttag ggaaaaataa tcctaataga ctatatctag cagaattaaa agtctcagaa
     2461 aatgatatct acttactcga aaaatttgat agagagaata gggaaaacgt tgataaatca
     2521 gagggtatga aaatcatacc caccctcgac gaaaaatcag acgctgaatc ccttggggct
     2581 caagagggta tgaaaatcat accgtgccaa aacgttgata aatcagaggg tatgaaaatc
     2641 ataccagaac ttaataataa tatattagac actaatagac acaatataga cactgaaaaa
     2701 gaccgcctac aagatcaatt gttgttagac aattttgaga caattatgac aaacgacagc
     2761 attgctacgt ttgtccctga acgagtatta aatttgataa aaacattttc ttcaagttac
     2821 agtgaagctc aaaaaaccgt ccagactatt cataatgcaa agaaaaaagc tgaaatagaa
     2881 agtggtattt cgatagtttt tgaagaactc gatagttatt atgtcaatgc agaacaagaa
     2941 ttatacacga cactgttaaa agcctatcaa aaattaaaaa ccgaaaaagt cgaaaatatc
     3001 cagaacctga tttttgtcta tgtaaaaaat tggtttatcg aaaaaccaat agctgctaaa
     3061 gtatcaagtg aaaaacgttt gaattatgaa agctccccaa gcactattac gaaagactgg
     3121 ttagagtgaa actttactga caaagtgatt gttgcttcat ggagtaacat taaaattaaa
     3181 aattttttat tattctaatt atattacgaa tattacaaaa taatagctat tttaatagaa
     3241 tttataagtt aaaatattat gataaaaatc acaaacgtag ccttttacgt cataagtgtt
     3301 aaaagaaata attaatttca aatatagaaa agggaacgta tgtttgcata ctcctttttt
     3361 ttgagttata ataatacgcg aagagagata atttcattat ttaaacaagc taaaaatctt
     3421 gatattactt cttttcaggc aatacgaata ttattcgctt acattttttg tataaattta
     3481 attgtctgct atgcttgtga tgaattgatt ttcgttctgc acttttggat gataaatttg
     3541 gacaattgaa aatacaaaaa aaagaaaggc ggtatgaact cggaaggctg gtaaccttcg
     3601 tcagcgttca tacacggcat taagatttgg cccttaatgc gttaaccttt cagtgttacg
     3661 gtattacccg caatggattt agtataacag atattcaaaa gtgataccac tttttttggc
     3721 tgtgttaagg ttaaaaatac gtgatattac gatgaatcta tgcctaagca caatgttata
     3781 aaaatgtccg tgtggctctt tgccgtatga cgaacgctga aattagaggg aacgcatgtt
     3841 tggatgcgtt ccctcttttt tgtttgtcat gaacgaaaat caattctcta tttttgaaaa
     3901 ataacaagaa aaacttgtta aaaatattta aagaaattgg gtggtttatt ttatgtcata
     3961 tacaggaatt ttgagtctca aagatatttg tcactacggt aaacggtgta ccgctacaga
     4021 gaaaatcacg aagaaactat caactggcca aagtaaaacc gttgtgcagt gtaagaaata
     4081 tataatccag aaagacaaag tctcagagga aatgatttat tacattggga aacaaaagca
     4141 aataatttta aaagatccta tccccttaaa agagctatat ccaacaatca aacatgttta
     4201 tgaccaaaac ggtgtactga ttggtcgaag aaaaaatgga gtcttgcgtt gtaccgcaaa
     4261 agggatgggg cgtttgatcg gctgaattga tcattctcat aacttgtatt ttatcgtttt
     4321 tcgcttgctt gaaaatattg tcgagacttc taaaggaact tagagtcact agaaaaataa
     4381 ggagtagact tgatctatca acaattccct tcggggagtg acggggtagg ttttaacgat
     4441 tggtaacgta aaaaattggt caatcgagta aatgcgcttg tttggatagt ggtgaaatga
     4501 atttgtgtaa ataataagcg cagagtaaac aagagggaat ttagaagtta gacaagttag
     4561 aatagcgtct agattaatca tgagcagcta ctaagggatc tagactttga cgcaaactca
     4621 tggaataagg agtaggtctt ctcgtaatgg ggaggacgca caagaaattg tgtcgtgtgc
     4681 tgcagtacat gtagatactt gcgaggacgt tgattattgg atcaatcgag catttaccgc
     4741 tgtctactag ggtttctcgt ttcggacgcc ataaacgagt cgaaattttt tatgtatttt
     4801 taagtaaacg aaaaacgata aaatatgaac aagtcctgaa taaagtgaaa aaattgatat
     4861 aaaacataga gaaaatgaaa tttacgtaat ggaggaatga caaatgaaaa attatgatcc
     4921 gaatatacga ttgggcacac atactattaa ggtttctttc caacgttggg attacaaagg
     4981 atttgtgacg tttagaagag gcggaaattg taaaggatta gatgttttag cattagacga
     5041 ggatgattta tacgatcaaa cattgactga taatccaatt ggattcggct tgctacctga
     5101 agatgatgaa ggtaatgaat ggtttaaaat gacgcttatg aatgataatg gagacgaatt
     5161 atctgttgaa gatacttggt catatttgag tgattatatt gtcagctttg aaatcattga
     5221 atttgtagcg gataaagaag aataaaaact ggaggaataa attttacaga taaaggctta
     5281 gaaggagtca cgatgattaa taaaaaggta gtattacctt aggcattgag taagga
//
LOCUS       DARPZJ010000106         5318 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.112, whole genome shotgun sequence.
ACCESSION   DARPZJ010000106 DARPZJ010000000
VERSION     DARPZJ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.112"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(178..681)
                     /locus_tag="SLE23_002728"
     CDS             complement(178..681)
                     /locus_tag="SLE23_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEI8469557.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(804..1568)
                     /locus_tag="SLE23_002729"
     CDS             complement(804..1568)
                     /locus_tag="SLE23_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEI8469558.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            1676..1951
                     /locus_tag="SLE23_002730"
     CDS             1676..1951
                     /locus_tag="SLE23_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEI8469559.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(2152..2499)
                     /locus_tag="SLE23_002731"
     CDS             complement(2152..2499)
                     /locus_tag="SLE23_002731"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469560.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            2667..3596
                     /gene="yidC"
                     /locus_tag="SLE23_002732"
     CDS             2667..3596
                     /gene="yidC"
                     /locus_tag="SLE23_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEI8469561.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            3699..5047
                     /locus_tag="SLE23_002733"
                     /pseudo
     CDS             3699..5047
                     /locus_tag="SLE23_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            5145..>5318
                     /locus_tag="SLE23_002734"
     CDS             5145..>5318
                     /locus_tag="SLE23_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8469562.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDK
                     LKQRDTVIIACVIW"
BASE COUNT         1705 a         1009 c          989 g         1615 t
ORIGIN      
        1 caaaagtcgt gtcaaagtcc cttgtttcga atgaatggtg ttcaaaagct tgcatctgca
       61 gtaataagcc gaaacttcac aaaaatttga gaagtaattt tcgtaaattc cttcttattt
      121 cttgaagctg accacttctg tcacaacctc aatatggtct attattggtt ttacctgtta
      181 aatcgaggat tctttcccaa agtaacgttg ccatctctta cgcatacttg cagacatggg
      241 ctgagccgct tctttgactg cgcagtattt gtccacgaat gtcacaatat atccttcttt
      301 atacttaggc ggtgcgatcg ttgcacccca catgtgcttc aaaatgatat ctcgctcaag
      361 atccgacaaa tcggtgattt tttctgcatt ctttacagca attcttggat ggatatacgc
      421 atgtgtcccc tcgtcaaatt tcgtcgtacg ccaatcatag tagaacagat catgcaaaag
      481 tccagcacgc gctgttgctt tagcattgcc accccatttt tttgcgagca gataactata
      541 gtaagaaaca ctgatggaat gctccaaacg agtggaatga acatgctgtg tgtaattcgc
      601 taattttttc actgcttctg tttctaaaag atcttgtaca taagacatat attcttcgtc
      661 ttcacgccat ttttctgtca taattatcga tctgccacct ttttgaattt cattttcttc
      721 tgaaattgat ctaagtatac caccagtgtt cggattattc tagtcgctct agataaaata
      781 gctaaagctt aatagttcct taatcataaa gaaaaatgat aaagaacgat ccctgctgcg
      841 actccgacat tcaatgattc cgcatttcct ttcattggga tatatacgtt ctgatcagtc
      901 aaagacaaga tttcctgact gactccctga ccttcgtttc ccatgattat agcgaaatcc
      961 tctgtttttt ctactttgtc taatgcatgt gcttcttcat ttaattctgt accgtacacc
     1021 gtaaaccctt tgcctttcat tacagggatt acatctgcca aatctttttg taacacaggc
     1081 aaatgataat tgcttccctg catgcttcgc agcacctttg tactataaat atctgccgtt
     1141 cctttaccta ataaaacacc agccatacca aacgcatctg ccgtacggat catcgttccc
     1201 acatttccag gatcctgtac attatctagt aaaagccagc ctcctgaaaa atctggcgta
     1261 tcttcagatg ttaacgtcat cactgctaag atcccttgcg gtgtaggtag atctgacata
     1321 gcggtcatga cctcatctga aactagaaaa gtagaaatct ctttgtttac agccagccag
     1381 tctccccatt ctttcatacc tctctgtgtc acaaaaagtt cttttatttc tgcatcagac
     1441 gacgcagctt cttcgatcag atggaaccct tccaaaagat attctgcctt ttcttctctg
     1501 tatttctttt tatgtagttt ttttaattct ttgattcttg gattttttgc tgattggatc
     1561 tctttcacat tccttcacct cacctgatta tatcatggaa taggtgcttg agcttgtttc
     1621 atcctaaaaa aatcggtatc attgatttat aaaacaggaa agaaaggtga cgaacatgcg
     1681 caaagttaaa atgaatgtcc aaggacgtgt ccagggcgtg ggatttcgct atatgaccaa
     1741 gatggttgct gatcagttag gcgtgaccgg aacggtaaaa aacgaagacg acggctcagt
     1801 cacaatcgaa gcaatcggaa atgacgacat catccaaaaa tttatcgaag aagtcaagaa
     1861 gtctccgagc ccaagtggac gagtgcagta tgtggatgtc caagaagatc cgatgattga
     1921 ggaacgaaag aaatttgatg tggtgggata aggttgtgaa aaggtcgctt agttttgagt
     1981 attaaggaaa attttgtgaa aatggctttc cacatttttg cataaatttg acttaatacc
     2041 gagaaactga cttttgaaca ccgtcgataa ggttgttttt gaagcgcttt gcctcgagta
     2101 ttaaggagaa acattttcaa aatagcttct catattttga aatgtaatga cttaataccg
     2161 agaggcagct gataaaacac cgtcaataag gttgtgaaaa agctggtctg catcaagcat
     2221 taaggactgg ttgtgaaaaa gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2281 ggctttccac atttttgcat aaatttgtct taataccaag aaactgactt ttgaacaccg
     2341 tcgataaggt tgtttttgag gcgctttgcc ccaagtatta aagacaggta gtaaaaaagc
     2401 tgatctatca cttgcagtga gttcatttga ctcctctatt tcgggcagaa taaaaaaagt
     2461 ttttagtttt ttaaataaga aagaaacact tggaatcact cttttctttc caagtatttc
     2521 tttcttgatt ttttgtcttt tttcaaaatt tttcgctacg aaaaagaaag aatatttata
     2581 tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt aagtttgtgt
     2641 aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta ttgggatccg
     2701 gacttgtcag tatcctgctc tttttatctg gctgtgtgcg gatggattca aacggaaacc
     2761 ctgacacttc aggaatcgtt tatcgagtac tcgtccatcc tatgggccaa gcgattacat
     2821 atctagttga gaatttcaat tggtcttacg gctgggcagt tattgcaatg actgtgatcg
     2881 tccgtatcat catcttgcca ctaggtatca gtcaatcaaa aaaaacaatg atccaatctg
     2941 aaaaaatgca agcgttaaaa ccacaagttg aagcagcaca acaaaaacta aaagctgcaa
     3001 caacacgtga agaacaaatg gcagcacaag cagaaatgca acaagtatat cgcgaaaacg
     3061 gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg ccgatcttct
     3121 ctgccttgta ttttacggct cgctacacag aaggtatccg tgaatcatct ttttacggca
     3181 tcgatctagg ctcaccaagt atggtgcttg ttgccattgc aggggtcgct tatctgcttc
     3241 aaggatatat ttcaacaatc ggtattcctg aagaacagaa aaagacgatg cgtacgatgc
     3301 tgatcgtctc tcctgctatg atcgttttca tgtcgatcag tgcgccagcc ggtgttacac
     3361 tttactgggt agtgggtggt gtgttcagtt gtctgcaaac attcatcaca aacgttatga
     3421 tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaatccg ccaaaacaag
     3481 tcgtcactcc aagaaaagac gtgacagaat cggcaaagcc agctgacaat aaacaaccaa
     3541 aaaacagtac aaacaacaaa ggccgcaacg caggaaagca gcaaaagcgg aaataaaaat
     3601 atatgacaaa aaactgtaga caaataaaaa aatttctttg ttctacagtt tttttgttac
     3661 aatcaaagaa aacgtcgctt ttcgaggagg aatgtataat gatgtccaaa taatcaatgg
     3721 atagtcgaat ggaagaagcc aaaatttcgc tagatgcact tgttcctaaa aatcatttgg
     3781 tccataaaat tgacaaaata ttgttatttg attttattta tccaattgtt gaatcaactt
     3841 actcgaccat tggtcgtcct agcgttgatc ctgtcatctt agtaaaatta gtattcattc
     3901 aatatttatt taggattcgt tcgatgcgtc agtccattaa agaagctgaa acaaacctag
     3961 cttatcgttg gtttcttggg cttagtttaa tcgataaaat tcctcatttt tcaacgtttg
     4021 gtaaaaacta tgtacggcat ttcagagaaa ccgattgttt gaacagatat ttatcattat
     4081 ccttgaacaa gcagttgaag ctagatttat tcatgaagaa attttgtata tggattcaac
     4141 ctatattaaa gcgaatgcga aaaaacatat ttttacaaga gaaatggtac ataaataagc
     4201 cattttatac caaaaacaat tgaaagaaaa aattaatgaa gcaagaattg cagaaggcaa
     4261 acgtcctttt ggttcaatca ttcatcagga ggtggtagaa gggaaaatta gtgtcgcaga
     4321 tccagaaagt ggttattatg taaaaacaga acaagaaaaa cagtttgctt attctgctca
     4381 taccgtttgt gatgaaaatg gttttgtatt agatgtcatg attacgcctg gaaatctaca
     4441 tgacagccga atgctcgtgc cacaaatcga acgtgttaaa tcatgttgtg gtgtagctgc
     4501 tgatgctgcg tacaaaacac cttggaacgc caagtattta atcgatcgaa aactacgacc
     4561 catttttcct tatactcgac ccaaaagaag caaagaacgt tttaaaaaga aagattttta
     4621 ttatgatccc tattataact ggtacctatg cccaaatgat caaacacttc agtttcgcac
     4681 aactactcga gatggttata aaaaatatgt atctaaatct tttatttgtg aaagttgtct
     4741 attattgaaa aattatacag aaagccagaa acaccagaaa gaaatacatc gacatattta
     4801 ggaagactac ttagatgaag cagaacattt acgccatacg gtgtacaatc gcgaaaaata
     4861 taaaaaaaag aaaagaaacg attgaacgcg tttttacaga cgcaaaggaa aagcatggaa
     4921 tgcgctacac caaatatcga ggcttggaaa aaaccaggtg catacgatgc ttgtttttgc
     4981 cgcaatgaat ctgcaaaaat tagccatttg gcagtggggg catatgtctt tatacccgtg
     5041 gtgctagtta attttttcct agaggaaaat gtctaaacat gttggtaaat caacaaaaaa
     5101 acgcatatag tagtctcaaa actcccaaga aatgaggact acatatgcgt tcatcaaaat
     5161 atactgaaca ttatacagat acttttataa cattcaagga aattatgaga actgtttcta
     5221 acatatacca caattgtgta ccagataaga ttaaaaaccg aagaaatact gataaactga
     5281 agcaacgcga tacagtgatt attgcttgtg ttatatgg
//
LOCUS       DARPZJ010000107         5256 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.113, whole genome shotgun sequence.
ACCESSION   DARPZJ010000107 DARPZJ010000000
VERSION     DARPZJ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.113"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(47..367)
                     /locus_tag="SLE23_002735"
     CDS             complement(47..367)
                     /locus_tag="SLE23_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEI8469563.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(515..2749)
                     /locus_tag="SLE23_002736"
     CDS             complement(515..2749)
                     /locus_tag="SLE23_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8469564.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQKAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3228..3494
                     /locus_tag="SLE23_002737"
     CDS             3228..3494
                     /locus_tag="SLE23_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEI8469565.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3494..5221
                     /gene="ptsP"
                     /locus_tag="SLE23_002738"
     CDS             3494..5221
                     /gene="ptsP"
                     /locus_tag="SLE23_002738"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEI8469566.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
BASE COUNT         1580 a          984 c         1057 g         1635 t
ORIGIN      
        1 ctttactttt gtcccacgct ctttaattat tatgttcaaa atttgtttac acggctaatg
       61 tagcgcctaa ttcatgtttt ggaatcgaga tttcaacaag gcctgccaat tcgattactt
      121 tgatttcatc ctcgtggtaa acggcgtctt tgattttatc taagaaataa tttttagcat
      181 cttcgatttc tttcggctgg attttacgtt tgtcattgat cagcagaatt tcattatgtt
      241 caggggcttc agtgtagaca atagtggtat ttccggctgt gtagaccttg actagatggg
      301 catcagtgtt ttcaagctgg tttaatacaa gacgggaatg gctgtttgtt acatttacca
      361 atttcatggc gctcacctct tttatgtatt tttaattgct tgtttctctt attataattt
      421 cttttttata aaatgaacag tattttgact tttctgaaaa aagaatgaga cggcatttct
      481 caaagaaata ccgtctcacg ctataaaact ggatttattc agccgtttct tcggctgatt
      541 ctttagccaa acgttctggt ttagaagtaa cgatgatttt tccatcttta tccagttttg
      601 ctttcaactc atggatagaa gggtgatcaa gataaaattc agcgatacca tcttcgattt
      661 gttcttggat cgtgcgtcga agaggacgag cacccataga tggatcatag cctaagtcaa
      721 ctaatttttc tttgacattc gtaggaactt cgatgtgaag ttgctgtgct gccagcattt
      781 ggttgacatc gtctagcatt agtgtgacga ttgtcatcaa gttttctttt gataatgcac
      841 tgaattcgat gatcccgtca aaacggttca gaaattctgg tgtaaagtag ttgtttaatt
      901 ggttcaatac agaacgagta acaccttcgc gtgccgcacc aaaaccaacg tttgcttcta
      961 ctttaccagt tccggcatta cttgtcataa tgatgatcgt atctttaaag ctgaccgttc
     1021 ttccttgtgc atctgtcaat cgaccatcat ctaagatttg caagaacata tgcaaaacat
     1081 ctggatgagc tttttctact tcatctaaca agacaagact gtaaggattt ctccgtactt
     1141 tttctgttaa ttgaccagct tcttcgtatc cgacataacc tggaggagaa ccaatcaatt
     1201 tagagacact atgtttttcc atatattcag acatatcgaa acgaatcatt gaatcttgtg
     1261 aaccgaatag ttcgtaggca agttgtttcg caagctctgt tttacctaca ccagttggtc
     1321 caacaaataa gaaggagccg attggacgat tctgtttgtt taatccaaca cggtttcggc
     1381 gaatcgcttt cgctactcga tctacagcgt tatcttgtcc gatgacatga gctttcaagt
     1441 catctgctaa gtttttcagt tgtgtctgtt ctttttcttt taattcaccc actggaatac
     1501 ctgtccgttg ttcaacgatt ttttccatat ctttttcggt aatcacaggt gtttcctctt
     1561 cagtgagctg acgttctttc attttttgaa gtttattgat ctgatcgcga taataagctg
     1621 ctttttcgaa atcttcttct cgagaagcta aaactttttg ttcttctgct ttttgcagtt
     1681 ttttctcgat tgttttagga tcaacgattt ggatcgtcaa gtttttctta gaacctgttt
     1741 catctagcaa atcgatggct ttatccggca agaagcgatc ttggacgtaa cgattggata
     1801 aagttgcggc tgcttcgatg gcctcatcag tatattttac atgatgatag tcttcataac
     1861 gtttttgcaa acctttcaaa atactgatcg tttcttcgac agttggttca tctacccgta
     1921 caggttgcat acgacgttct aaagcagcgt ctttttcgat gatgcggtac tcatttaagg
     1981 tagtagcacc aaccatttgc aattctcctc gagctaaagc tggttttaaa atattaccag
     2041 catccatatt tccatcacca gcagaaccag caccgactat ttcgtgaact tcatctatga
     2101 ataggatcac attttctgct tgacggatct cttcaatcaa tttttgcata cgttcttcaa
     2161 attgtcctcg tataccagta ccttggacta aagatacgac atctaaacga atgacttctt
     2221 tgtccattaa tttttgcggt acatcaccat ctacgatttt ttgtgctaaa ccttcaacaa
     2281 ctgctgtttt accaacacct ggttctccaa tcaagacagg attgttcttg gttcggcgat
     2341 ttaaaatttc aatgactcgt ttgatttcgt catcgcgtcc gatcacagga tcgatatcac
     2401 cttgtcgtgc ttgttctgtg atattgattc cgtattctcc caataaacct tctgtattgc
     2461 cttgaggtgg ctgaccacca ttgaagttgt tgtttccgcc aaattgtgtt ggtggtgttt
     2521 gctcataatt tccttgctgt tgcatttggc gagacatgga acggaaaaga tcgtccaaac
     2581 tgccaaatcc aaatggatca ttttgggcca tattagtcag acctccattt tgttgatttt
     2641 tgattttttg ataacagctc tgacagtaat cgagttgtgt ccgctgacca ttgacagtgg
     2701 catacaagtg aatcgttgcc tcattcttgc cgcagttttg acaaagcatg aatcattcac
     2761 gtcctttcac aaaaatgggt acatccatat tttacatctc gtttttcatg aggtaaaaga
     2821 ataaccccta gttttttaag agatttatga ggtagaaaag gtgaaatctc tattgaccat
     2881 tcctgacctt tgactcttat tatactaaaa ataaaaaggg aagcaagtaa ttcgtttcat
     2941 atgaaaacaa agagggtcaa aggaaagaat gataaacgtc aggagaagag aaagcgacaa
     3001 gaaaaaggaa ataaacacgt ttgttataaa atgtgaagaa aaggatgaaa aagaatccgg
     3061 aataatttga atacttttat ctgaaattga atgaaaactg ttgtatctaa cgaaaaaaaa
     3121 tgttaatctt tacagatgaa agggtggcat ttgttaggat tctctgaatt actaaaaaag
     3181 aaaaccctca cataaaaaca acactcactt aaaggagacc gattaatatg gaaaagaaag
     3241 aatttcacgt agtagcagaa actgggatcc acgctcgtcc agctacacta ttagtacaaa
     3301 cagcaagcaa atttaactct gatgtaaact tagagtataa aggtaaatca gtaaacttga
     3361 aatcaatcat gggcgttatg tctttaggtg taggtcaagg ttctgatgtt actattactg
     3421 cagaaggtgc tgacgaagct gatgcaatgg cagcaatcgt tgaaacaatg aagaaagaag
     3481 gcttatctga ataatggttg aaatgctaaa agggattgcc gctagtgacg gtgtagccgt
     3541 tgcaaaagct tacctgctag ttcaaccgga tttaacattc agtaaggcaa cagtagaaga
     3601 tactgcggct gaagaagctc gtttggatgc tgcattagct aaatctactg aagaattgca
     3661 gcaaattcgt gaaaaagcag cgcaaagctt aggtgaagca gaagcgcaag tatttgatgc
     3721 ccatttgatg gttctttcag atccagaaat ggtaggtcaa atcaagcaaa atattaaaga
     3781 caacagcgta aatgctgaat cagcgctaaa agaagtaacg gatatgtata tcggtatgtt
     3841 cgaagcaatg gaagataatg cttatatgca agagcgtgct gcagatattc gtgacgttgc
     3901 taaacgtatt ttagcgcact tattaggcgt tactttacca aatccatcaa tgatcaacga
     3961 agaagtggtc gttgttgcac atgacttgac tccaagtgat acagcacaat tagatcgcaa
     4021 ttttgtaaaa gcgtttgtaa cagacattgg tggacgtact tcacattctg ctatcatggc
     4081 acgttcttta gaaattccag caatcgttgg gacaaaagaa attactgcta aagtcaaaga
     4141 aggcgatatt ttggctgtca acgggatcga aggcgatgta atcatcgatc ctacagatga
     4201 acaaaaagct gaatttgaaa aagcaggtgc agattacgca gcacaaaaag cagaatggga
     4261 aaaattaaaa aatgcagaaa ctgtcacagc tgacggcaag cattttgaat tagctgcaaa
     4321 catcggaaca ccaaaagatc tagttggtgt ccataataat ggtggagaag cagttggtct
     4381 gtaccgtact gaattcctgt atatggattc tccagacttc ccaacagaag atgaccaata
     4441 tgaagcttac aaagctgtat tagaaggtat ggaaggaaaa cctgtagttg ttcgtacaat
     4501 ggacatcggt ggagataaag aactaccata tctgcaatta cctcatgaaa tgaatccatt
     4561 cttaggatat cgtgcattgc gtatcagttt atctgaacaa ggcgacgaaa tgttccgtac
     4621 acaaatgcgt gcattgcttc gtgcatctgt tcatggtaat ttacgtatca tgttccctat
     4681 ggtagctaca ctcaaagaat tccgcgcagc aaaagcgatc tttgaagaag aaaaacaaaa
     4741 attgataagt gaaggcaagg aagtatctga tacgatccaa gtcggcatca tgatcgagat
     4801 tccagcagca gcagtcttag cagacaagtt tgcaaaagaa gtagatttct tctctgtagg
     4861 tacgaacgat ttgattcaat acacaatggc agcagaccgt atgaacgaac gcgtttctta
     4921 cttgtaccaa ccatataacc catcaatttt acgtttgatc aaaaatgtaa ttgatgcagc
     4981 acacgctgaa ggaaaatggg caggtatgtg tggagaaatg gctggagatc aaacagctgt
     5041 tccattgcta gtaggtatgg gtctagatga gttctcaatg agtgcgacat ctattcttaa
     5101 aacgcgtagt ttaatgaaac gcttggacac agcgaaaatg gctgaacttg ctgatcgtgc
     5161 attgaaagaa tgcgatacga tggaagaagt cgttgaactt gttcatgaat atgtaaaata
     5221 aacaacgtat caaaagctgg tgtggcttgt aaaaga
//
LOCUS       DARPZJ010000108         4807 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.114, whole genome shotgun sequence.
ACCESSION   DARPZJ010000108 DARPZJ010000000
VERSION     DARPZJ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.114"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="SLE23_002739"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="SLE23_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEI8469567.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="SLE23_002740"
     CDS             complement(3250..3768)
                     /locus_tag="SLE23_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEI8469568.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          730 g         1712 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa
     4021 aatcatgtta actactatca attactaata aaaactacca ctttaagcgt taagaactgt
     4081 taagtttagt taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta
     4141 aaactcaaaa tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt
     4201 aaaaaatatt atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa
     4261 cagctacaaa aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca
     4321 tattcacgcc tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt
     4381 taggaaattg aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca
     4441 ccagatattc ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac
     4501 cgcgaattta ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt
     4561 aagggatcaa gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa
     4621 acaattatag aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact
     4681 ttcttattct gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta
     4741 cgagtactat tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc
     4801 ccactta
//
LOCUS       DARPZJ010000109         4791 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.115, whole genome shotgun sequence.
ACCESSION   DARPZJ010000109 DARPZJ010000000
VERSION     DARPZJ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.115"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(75..1073)
                     /locus_tag="SLE23_002741"
     CDS             complement(75..1073)
                     /locus_tag="SLE23_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HEI8469569.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="SLE23_002742"
     CDS             complement(1148..1444)
                     /locus_tag="SLE23_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEI8469570.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="SLE23_002743"
     CDS             complement(1437..1730)
                     /locus_tag="SLE23_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469571.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="SLE23_002744"
     CDS             complement(1876..2427)
                     /locus_tag="SLE23_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HEI8469572.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="SLE23_002745"
     CDS             complement(2601..2900)
                     /locus_tag="SLE23_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HEI8469573.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEIGTLPKDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3235)
                     /locus_tag="SLE23_002746"
     CDS             complement(2927..3235)
                     /locus_tag="SLE23_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEI8469574.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQLPLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY
                     "
     gene            3540..4223
                     /locus_tag="SLE23_002747"
     CDS             3540..4223
                     /locus_tag="SLE23_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469575.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIE
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4260..4757)
                     /locus_tag="SLE23_002748"
     CDS             complement(4260..4757)
                     /locus_tag="SLE23_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8469576.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1424 a          908 c          700 g         1759 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttt aggaagtgta cctatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaagttgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3241 ttccctcctt tgctataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc gtggtgctag
     3421 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
     3481 tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat ggttacgtcg
     3541 tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat atccccgatt
     3601 atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat cgtgttttaa
     3661 aaggcatcga aatcggttac atcgcttctg aaaaggatcg gatcatcgac tatttagccg
     3721 ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt gattatttag
     3781 atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt gcacaacttt
     3841 cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat ggttttcggg
     3901 tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta ccgattctag
     3961 atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct tacttgtatg
     4021 acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt ggtaccttgt
     4081 ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc gatgatcttt
     4141 ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa ggaaagcgaa
     4201 ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag gacgtttttt
     4261 tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg aaaatgtttg
     4321 atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg atttttttca
     4381 taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt cgcttcatcg
     4441 agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag ccgttgaatc
     4501 tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg atgatcctta
     4561 ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc agttgtcaat
     4621 tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa cgattcataa
     4681 aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa atacgctagt
     4741 gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa t
//
LOCUS       DARPZJ010000110         4663 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.116, whole genome shotgun sequence.
ACCESSION   DARPZJ010000110 DARPZJ010000000
VERSION     DARPZJ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.116"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            4..165
                     /locus_tag="SLE23_002749"
     CDS             4..165
                     /locus_tag="SLE23_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HEI8469577.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            184..1461
                     /locus_tag="SLE23_002750"
     CDS             184..1461
                     /locus_tag="SLE23_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469578.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1471..2127
                     /locus_tag="SLE23_002751"
     CDS             1471..2127
                     /locus_tag="SLE23_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469579.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2127..3503
                     /locus_tag="SLE23_002752"
     CDS             2127..3503
                     /locus_tag="SLE23_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469580.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3789..>4663)
                     /locus_tag="SLE23_002753"
     CDS             complement(3789..>4663)
                     /locus_tag="SLE23_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8469581.1"
                     /translation="DSQVAFQLVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRP
                     CLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTRERYREYKSNPKECVN
                     CPLLNQCTKSKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKE
                     KHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQ
                     ARVTSLEQLLSTVCDVGDISFSIRNQLRFKRSLPVSGNINVYFTKARFKRLIAITVSS
                     IVMFLWLFRMGVIP"
BASE COUNT         1790 a          574 c          823 g         1476 t
ORIGIN      
        1 ccgattcagg ataaggataa gtgtattaat tgtggaaaat gtaaaaaagt ttgccaaatg
       61 aataaagatt cagttgagaa ttgcaatcat ctggagtgta tcagatgtgg acgatgtaaa
      121 aatgcttgtc cagtggatgc aattagttat ggagtaagaa aatagagagg agtagttagg
      181 aaagtgataa aaaatgctat agcatatatt acaagaaaga aaaatagaac tttaataatt
      241 tttatcatat taactatagt tctttcttgc ttgtattctt gtttaacaat aatgaaatca
      301 agcaatgaaa tagaaaaggc tttatatgaa agttctaatt cttcaatatc aataacaaaa
      361 aaagatggta aatattttaa tgttaatcaa tttaaagata ttgaaaaatt aaaagaaatt
      421 gaagaaaaaa taattcaata tgatggatta gcaaaattaa aagatgctaa agtagttagc
      481 ggagaacaaa gaataaatag agaagattta tctgacgaat ttaagaatgt tgtttcactc
      541 gaagctacaa ataatactaa aagaaatatt ttatttagta gtggagtatt tacaattaaa
      601 gaaggtaaaa atatagaaga aaatgataag aattcaatta ttgttcatga agaatttgct
      661 aaacaaaaca atctaaaatt aggtgatgaa gttgatcttg aattactaga tattgaaaaa
      721 agtggaaaaa taaaaagtca taaatttaaa attataggga tcttttctgg taaaaaacag
      781 gaaacatata caggattatc ttctgatttt agtgaaaata tggtgtttgt agattattca
      841 acaagccaag agatattaaa taattcagaa aataatgaaa ttgcaaataa aattttaatg
      901 tattctggta gtgcagaatc tacagactta gccttaaaca aattgaaaga gcttaaaatt
      961 gatgagtcaa agtattttgt tgaaaaagat tctaatgcgt ttgaagagtc tttagagtca
     1021 gtgagtggaa taaaatatat aataaaagta atgacttatt ctattatgtt aggtgggatg
     1081 gttgttcttt cattaatctt gattctatgg ttaagggaaa gaatttatga aataggtata
     1141 ttcttatcta ttggaacatc taagatacaa attataatgc aatttatatt cgagttaata
     1201 ttcatatcga taccaagtat aatatcttcc ttatttttag gaaatgtatt actaaaagta
     1261 attgtagatg gattcattaa ctcagaggat tcaatgattt ccggtggaag tttaataaat
     1321 aatagtagtt ttatgtcaaa tataacaaca cttggacaaa gttatttaat attaataagt
     1381 attattgttt tatcagttgt atttgcttct tcattaatgt taatcaagaa gcctaaagaa
     1441 atcttatcaa aaataagtta ggagaaaata atggatatat tagaaataaa gaatgtagca
     1501 tatagttatg caaattctaa agaaaaagtt ttgtcaggag taaatcaaaa atttgaactt
     1561 gggaagtttt atgcgatagt aggaaagtca ggaacaggaa aatctacact tctttcctta
     1621 cttgctggac ttgataaacc tcaaacagga aaaatattgt ttaagaatga agatatacaa
     1681 aataaaggat atagtaatca tagaaaaaat aatatatctt tagtatttca aaactataat
     1741 ttaatagatt atttatcacc aattgaaaat attagattag taaataaatc agcagatgaa
     1801 agtatcttgt ttgaactagg tttagataaa aaacaaataa aaagaaatgt tatgaaatta
     1861 tctggtggac agcaacaaag agtagctatt gctagagcat tggtatcaga tgctccaata
     1921 atactagctg atgagcctac tggtaatcta gacagtgtta ctgctggaga aataattaat
     1981 atattaaaga cattagctaa agatagaaat aaatgtgtaa tagttgtaac acatagtaag
     2041 gaagtagcag attctgcgga tatcatttta gaactaagtg gtaaaaagtt gaaaaaagta
     2101 aataaaatga atttggaggt tgaataatga taaaaaatgc atttgcttat gtaactagaa
     2161 aaagtttaaa atcattaatt atcatattag ttattttatc tatgtcaact ttaagtctca
     2221 ttagtttatc tattaaagat gctacggaca gagcttcaaa agaaacattt gctaatataa
     2281 caaatagttt ttctatggag ataaatagac aagtaaatcc aggaacacct agaggtgggg
     2341 gaaatgtaaa aggtgaagat attaaaaaga tatctcaaac agatagtata gactcctatg
     2401 taaaaagaat aaacagtgtt gcagatttag ttgattatga tattattgaa actcaagaga
     2461 ctcttgcgaa tcaatcacct gaaagagcaa agaattttaa aagaacagtt atgttaactg
     2521 gggttaacga ctcaacaaaa gaaacaaaat ttgtatcaga agcatataaa ttagtagaag
     2581 gaaagcattt agaaaatgaa gataaaaata aaatcttaat gcataaagat ttagctgaaa
     2641 aaaataacct taaagttgga gataagataa aaataaaatc taatttattt gatgctgata
     2701 atgagaaagg tgcagatgaa acagtagaag tagaaattaa aggtctattc gatgggcata
     2761 atagcggtgt agtaagtgca gcacaagaac tatacgaaaa tacattaatc actgatattc
     2821 atacagctgc taaagtttat ggtaataccg aagatacagc tgtataccaa gatgcaacat
     2881 tctttgtaaa aggtgataag aatcttgata gtgtaataaa agatcttggg aaattagata
     2941 taaattggag agaatataat ttgattaaaa gttcatcaaa ttaccctgca ttacaacaat
     3001 ctatatcagg tatttactca atttcaaata aattattttt tggctcatta atatttgcag
     3061 gagttgtagt ttcattatta ttattcttat ggatgaatgc tagaaagaaa gaaatagcag
     3121 tattactatc attaggtata tcaaaattag aaatttttgg tcaattccta attgagatgg
     3181 tatttatatc aatccccgca ttcgttggtt cctatttctt agctcaatat acagctgaca
     3241 agcttgggaa taatatattg aataaggtta ctggtgatat agctaaacaa atagctaaac
     3301 aatctgcatc tagccaatta ggtggtgggg cagaagctga aggatttaac aagacattat
     3361 caagtttaga tatcaatgta ttacctaaat tcatgattta tgtagttata tttatgagtt
     3421 tagtacttct tgtatcattg attatttctt cattcaatat attaagaagg aatccaaaag
     3481 aattattaat tgacaataat taaaattttc ggtgcttttt agcaccaaaa atgagagtgt
     3541 aatataaacc gtgtaagtaa ccatcaatcc taggcgggtg gttgcttcac ggtttttatt
     3601 tttctaaaat aagatcaaga ggtgattaca cgatggctag aaagaaaaga aatcctgatg
     3661 ctgagaagtt agctgaatcc attttgaata cttatcaacc cgaatctgta gaggatatgc
     3721 aagatgtttt aaaagatgtg tttggtccct tatttgaaaa aatgcttcaa ggagaattga
     3781 ataaccattt agggtatgac gcccattcta aagagccaaa gaaacatgac aatcgacgaa
     3841 acggttatgg caataagacg cttaaaacga gctttggtaa agtaaacatt gatgttccca
     3901 gagaccggga ggcttctttt gaacctgagt tgattcctaa tagaaaacga gatgtctccg
     3961 acatcgcaga ctgtagacaa aagctgttcc aaactcgtaa ctcgagcttg gaacagcttt
     4021 ttatctactt cgtttcgaat ttttgaacaa aaaaataaag gctccttgcc tttccatagc
     4081 caggtggcta atttctttaa attcattgca gcaaacacta gcatcgtatg cgtcgcgact
     4141 ttttccaagc ctcgatactt ggtccaacgc atcccatgct tttcttttgc atccgcaaat
     4201 attcgttcaa tcgtttgttt ccgttttttg taaattgatt tattcagatc tgttaggcga
     4261 agatgttcca cttcatccat cagatctccc caaacatgtc tcgtgatgac tcgttgatga
     4321 tttttacttt tggtacattg gtttagcaga ggacagttca cacattcttt tggattggat
     4381 ttgtattctc ggtacctttc tcgagtaacc gttgaaaaag cgagcatttg atcttgcgga
     4441 caaatataac aatcaaaata ctcgtcatag agaaactcat tttttgataa tagccccttt
     4501 ttccctttgg gccttgaata aggcaaacaa ggtcgaaggt tcaaatgagt caaaaagtga
     4561 acaaacttag gtgtcttata cccagcatca gcgacaacac aattgatttc aggaaaaagt
     4621 ctcttcgatt gtttgacgag ctgaaaggcg acttgactgt cat
//
LOCUS       DARPZJ010000111         4662 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.117, whole genome shotgun sequence.
ACCESSION   DARPZJ010000111 DARPZJ010000000
VERSION     DARPZJ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.117"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(172..474)
                     /locus_tag="SLE23_002754"
     CDS             complement(172..474)
                     /locus_tag="SLE23_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469582.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="SLE23_002755"
     tmRNA           complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="SLE23_002755"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1231..2004)
                     /locus_tag="SLE23_002756"
     CDS             complement(1231..2004)
                     /locus_tag="SLE23_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEI8469583.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2148..2498
                     /locus_tag="SLE23_002757"
     CDS             2148..2498
                     /locus_tag="SLE23_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEI8469584.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2479..3195
                     /locus_tag="SLE23_002758"
     CDS             2479..3195
                     /locus_tag="SLE23_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8469585.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3195..4643
                     /locus_tag="SLE23_002759"
     CDS             3195..4643
                     /locus_tag="SLE23_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8469586.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
BASE COUNT         1550 a          822 c          900 g         1390 t
ORIGIN      
        1 ttataattgg agtggtagtt aattagtgac ttatttttga ttttatagca ctgatactat
       61 aaaatataga tatcatcata ttacacaatc ttaatactaa cttaaaaaat atccctttta
      121 taagtatggt gataaaatcc gttccgggct acctttttta ggtagcctac tttaatcttt
      181 atacctttct ggatcaacga aagtatactt caaatagtca taacgccgat gatcgctccg
      241 tgcgtctggc acatcagtca cgatatcaaa caaaaaatac acatctttct tcattctggt
      301 ttttgttgcc ggaattttaa agtagttctt attagagtaa tagagattga ttaataagct
      361 atcttcgatt gctaaaaaga aaacttctga atcccacacc ttataaaaat ctttgacaaa
      421 tctattcgaa ggatcaaatt taaaccataa ttgtgttttt ccttccatca acataatgtt
      481 cacctcaaaa agagtatacg aactaatgtt ctttttgtaa agtaggaata tcattgataa
      541 tatggatgga acatatatat taaaaagtgt tctttttgaa tgctattttg aatgccattt
      601 tcattcattt aacgaaaatc tgcgaaaata aaaaatgctc aaacccttat aaaataagga
      661 tttaagcatc tagcgaaatc tgctgaaatc tcacaatgga gacggcggga gtcgaacccg
      721 cgtccaaaca catcgccact taaaaatcta cgttcatagt caactcattt aaggattcac
      781 tttacagctt gccgagtgac aggcattctg tatcgctagt ctgatgttct ctttttcaac
      841 ttacagacgg aaagttgaaa cgtatcccac taaagttagg acccttactc gagcacatgg
      901 gcgatgccga gaggatctac gctaactgtt tttaggcagc taaagcgtaa gagttgtttt
      961 cgtttttagc agttatattt aactgtaacg tttttacgta gacgtaacct acgaaacgca
     1021 attcaagctc gactgtgcct gtcgaatccg taacgtcccc gttagctaac aagggttacg
     1081 tgtatttttc atacaaaatt agtatagcat atattgggat aaattcaata aaaaagcgaa
     1141 tcatatccca ttatttatat aataactgcc cctttcttaa gaaaaaataa gcgattttct
     1201 taagaaaaga ggtagcttca aaaaaagatc ttaaatcaga tcaaaatact tcaatgcgtg
     1261 gacaattccg ccttctgtat ttttctttgt gataaaggta gaaagttctt ttaatccgtc
     1321 ataggcgttg cccatagcga ttttgttgtc gcaagcttcc aacaaggcaa aatcattcgg
     1381 accatcgcca aatccaaaag taggaacttt ttccagctga agttcttttt gcagacgttt
     1441 gacacctgcc ccttttgaga ttcctttctt cactgtatcg atcgagtaag gaccattccg
     1501 ataaaaagtt agctcaggaa aatgttcgtg atagtattcg tcacctgatt gagataagat
     1561 cagcaacata tttactgtgt tttctttaaa gcctaaagga tcaatttccg gaacatctga
     1621 atgaatgaag tcgtaagcat tgatcattgt ttggctatga ccggtacacc agattttctg
     1681 atcgttatag taagaaagtt catgaccgtt caactgtaca tgatcataca ttttttgaca
     1741 ttcttctgaa gaaaatgttt gagaatagat ttcttcgccg tctactcgaa tgaaagaacc
     1801 attcatggtg accgcagaag taatgcccgc atcttccatg atagagtgga tttctgcttc
     1861 tgtacgtcct gtagcgatga cggggagaac attgttttct tttaatgcgt tcatagcttt
     1921 tgccacttcg ggtgtgattt ttgatttcgc atctagtaat gttccatcaa gatcaaagaa
     1981 agtgattgca cgataatttg acacaaataa aactcctttt ttattggaat aagtttatct
     2041 taacaaagaa tgaacaaaag acaaaccttt cgtgaagaat tcctgaacat attggttcag
     2101 tcaacaattt agagtatact ataagaagag aatttaggag ggaaagaatg atttttttca
     2161 gtattggtat cttattctta ataattggca gtctttttcg gattctgccc tcaaaaggaa
     2221 atctgccttt ttatgggtat cattcgcctc ttgccgcaaa aacagacgct cattggcggc
     2281 tggctcaaaa gacaagcgga aactggtttt ttcttatggg cttactgatg gcattgatcg
     2341 gctattattt aaagacatct gggcatacga attattttct gattgaaatg cttctgctag
     2401 tatttccaat tatgcctatt tttattatga cagaaaagaa attacagaaa tatgacctgg
     2461 aaactggagg gaacgataat gaatatttta atgattgaag ataatcaatc tgtttctgaa
     2521 atgatgcaga tgtttttctt aaatgaaggt tgggaagcaa ctttcaagta tgatggaaaa
     2581 gaagggctcg atgccttttt agaaaaccca caacattggg atatgattac actagacctg
     2641 aatttgccca cactggacgg tatgctagta ggaagagaga tccgcaaagt ttcaagtact
     2701 gtgccgatta tcatgctgac agctagagat tctgaaagcg atcaggtgat cggcttagag
     2761 atgggggcag atgattatgt cacaaaacct ttcagtcctc tgacgcttat tgctcgaatg
     2821 aaagctttgc atcgccgtag tgagttggca gaagcaagag aagaagcagt agtttcagat
     2881 gatcattttg atatcgagac tagtcatttc aagatgaata cgaaaacacg agaagcgtat
     2941 ctggacaacc ggccaattga aggactgacg cctaaagagt tcgatctatt gtttacttta
     3001 gcaaaaaaac cacgtcaagt attctctcgg gagcagttgc ttgaattagt ctgggattat
     3061 cagtactttg gtgatgaacg gacagtggac gcccatatca agaaattacg acaaaaaatc
     3121 gaaaaggtcg gaccacaagt catccaaact gtttggggag tcggctacaa attcgatgat
     3181 tctggtgttg cctaatgcgt tatttgtatc agcaactctt agctttctgc ggaatggtcg
     3241 cgttgatctt attgatcgtt ggagtttctt ttacacaact gacaaaacaa acgattgaag
     3301 aaaacaatta ccagcaactg tttggatatg ctgaatcagt tgaaaagaca acgcaaacct
     3361 atgccgatac gctcccgcag tttagtcaag atcaggcgtt tcaaaatgca ttgctgctga
     3421 cagagcaagt actgacagaa caaaatgtga actttatatt tatcgataaa aacgaacgtg
     3481 tcatttatcc gactaataca gctttactga attttacctt aacagctgat caatggaaaa
     3541 atctgaggaa tggacgtcaa gaaaaattca catcgaataa aaatatttta ggacaagcac
     3601 aggcgacctc ttacgcactt gtgccattta atttgaatca tgaattctat ggagcacttg
     3661 tagttagtca acctgcgcga aatatcgata acagcgttcg tccaattaca ctgaacctgt
     3721 tcaaaggatt tattttttcc agtatcgttg cagttattgc cagctatgct tttgcagcat
     3781 tccaagttaa gcgtatcaat cggttaagga atgcgacgaa agaagtgacg aatggtaatt
     3841 ttgatgtaca gctccccgta catgacaaag atgaatttga tgagttagca gatgatttca
     3901 ataaaatgac gaattcattg aaagaatctc aagcagaaat tgaagaacaa gaaaatcgtc
     3961 gaagacaatt tatggcagat gcttctcacg agatgagaac acctcttacg acaatcaacg
     4021 gacttctgga agggttagaa tacaatgcaa tccctgaaaa tcagcgagaa aacgcgatta
     4081 aattgatgaa aaatgaaaca gagcgtctga tccgtttggt gaatgaaaac ttggattatg
     4141 aaaaaatccg tacgaatcaa atcagtatgg tcattaaaaa attcaatgga acagaaacat
     4201 tgaaaaatat tgttgcacag ttagaagcta aagcagaagc agcaggagat acattgacat
     4261 tgaaagccgt tgatgatatt gatgtttacg ctgattatga ccgatttgtc caaatcatgg
     4321 tcaatattat tcaaaacgcg atacagttta ctgaaaacgg ccaaatcacg attactttag
     4381 aaaaaggcta tcttgaaacg atcatcacga ttgaagatac gggaattgga atgtctgaac
     4441 aacaaatgaa aagtatctgg gatcgttatt ataaagtaga tccttcaaga aaaaatacaa
     4501 aatatggtga atcaggatta ggtttaccaa tcgtgcagca acttgtacgc ttgcataaag
     4561 gaaaattaga agtagaaagc gaactaggaa aaggaacaaa attcgctgtt cgtttgcctg
     4621 acgtagaaat caaaaaagag taaaaaacaa gcggtataaa ag
//
LOCUS       DARPZJ010000112         4617 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.118, whole genome shotgun sequence.
ACCESSION   DARPZJ010000112 DARPZJ010000000
VERSION     DARPZJ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.118"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(15..962)
                     /locus_tag="SLE23_002760"
     CDS             complement(15..962)
                     /locus_tag="SLE23_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HEI8469587.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="SLE23_002761"
     CDS             complement(1140..1943)
                     /locus_tag="SLE23_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEI8469588.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="SLE23_002762"
     CDS             2089..3003
                     /locus_tag="SLE23_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEI8469589.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="SLE23_002763"
     CDS             3051..3521
                     /locus_tag="SLE23_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEI8469590.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="SLE23_002764"
     CDS             3606..4214
                     /locus_tag="SLE23_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEI8469591.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="SLE23_002765"
     CDS             4348..4548
                     /locus_tag="SLE23_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8469592.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1512 a          716 c          912 g         1477 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttaga
//
LOCUS       DARPZJ010000113         4434 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.120, whole genome shotgun sequence.
ACCESSION   DARPZJ010000113 DARPZJ010000000
VERSION     DARPZJ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.120"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(543..2048)
                     /locus_tag="SLE23_002766"
     CDS             complement(543..2048)
                     /locus_tag="SLE23_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEI8469593.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="SLE23_002767"
     CDS             complement(2045..2731)
                     /locus_tag="SLE23_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEI8469594.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="SLE23_002768"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="SLE23_002768"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEI8469595.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1547 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attt
//
LOCUS       DARPZJ010000114         4401 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.121, whole genome shotgun sequence.
ACCESSION   DARPZJ010000114 DARPZJ010000000
VERSION     DARPZJ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.121"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(99..1619)
                     /locus_tag="SLE23_002769"
     CDS             complement(99..1619)
                     /locus_tag="SLE23_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEI8469596.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1862..2047)
                     /locus_tag="SLE23_002770"
     CDS             complement(1862..2047)
                     /locus_tag="SLE23_002770"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HEI8469597.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(2031..2213)
                     /locus_tag="SLE23_002771"
     CDS             complement(2031..2213)
                     /locus_tag="SLE23_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469598.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2454..2672
                     /locus_tag="SLE23_002772"
                     /pseudo
     CDS             2454..2672
                     /locus_tag="SLE23_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3167..3766
                     /locus_tag="SLE23_002773"
     CDS             3167..3766
                     /locus_tag="SLE23_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8469599.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3830..>4401
                     /locus_tag="SLE23_002774"
     CDS             3830..>4401
                     /locus_tag="SLE23_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HEI8469600.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIG"
BASE COUNT         1403 a          799 c          785 g         1414 t
ORIGIN      
        1 ataattcagt agttttgagc gtaagcgtgt catagaatgg tacctaaaca caaatagccc
       61 gatttgatac actcaaatca ggttatttgt ggcttatatt atttacagat ttcttgtatc
      121 tgctgattcc atggcaaata agcgcgtagc gcttcaggtg tcatcgaaga cagattggga
      181 atctctgtaa aaagatgatt taaatatttg cggatgttta acccattcgc aacagctgtc
      241 tggataatac tcaatataat tccatttgat ctagcgcctt ttaagctttt agaaaatagc
      301 cagttttttc gaccgatcac taactctttg atggcacgct ctgctcggtt atttgaaagt
      361 tccaagcgtc catcaagcaa cacaatctga agtccgtctt tatgattgac tgcgtattga
      421 accgcctttc caagctgcga ttttggcaaa taagcaaaac tctcacacca atgaaaaaat
      481 tcagtcatca caggctgcaa cgtttccttc ctcgctacaa acctttcttc tgcgctaagc
      541 ttattaaagg tccgttcgat tcgaaacatc ttgtcacaga agtctaatcc tattttggca
      601 tgactttttg gggacggttg tttacccaat gcttcaaaaa actttctgcg aacatgcgcc
      661 caacaataaa cattgtttac cggcagcttt ccataggccg cgtaaccatc agtatgcaag
      721 aaaccgctaa atgattctaa aaaacttttt ggctcatcaa cggaacgcga atttgcgtgc
      781 tcgtagagca caacttgttt ttcttcgctt ttacctgaag catataacca gtaaaaggtc
      841 ttttctttat gagtattcaa tacccgatag cttgtctcat ccgcgtgtaa gacctcctga
      901 ttgcttaatt cttgatgaag gcaattgtag attggctcta aaaccatttc acttaccttg
      961 atatgccaat tagtgatttt tttacgatca agagggaaac caagtgcatg ccattctttt
     1021 tcttgtcgat atgccggcac ctttttaaca aatttttccc aaatactctg tgtcacaatt
     1081 gaagaggaac ctagactatt attgatcaac ggtttaggaa caggcgcttt tttgattttt
     1141 gtttctccta atgcttcaca ttctctgcaa tgataggcat gttggtagat gacttgtttt
     1201 tctatatggg caggaacata caatggctct tctctaagcc ttgtcgcacc gatatcatgt
     1261 aaagtatgac cacagtcttc acacaaacaa tcggcacctt ttaattcata atgaatagga
     1321 acttcaggca gaccttctaa tgaaagtgct ttgagtccct tgcgttttct gcgtttaaaa
     1381 gaagataccg taatgggttc ctggctttct tgtccagtgt gctctggttc attaaaagtt
     1441 gagtcgtcta ataaatcgat ttgcccatct acgggtggtg tttctttttt tcgtccaaac
     1501 aagcgtcgat tcatttcagc aatttgttct ctaagaagag tattttcctg ttgctggatt
     1561 tcaagcaact gtgttaattg cttgatttgt acaagaagtt cagattccat ttttgtcatt
     1621 tttacaccac cattctagcg attttcttac atctattata ccattttatg acaacgaaaa
     1681 acagacaaaa tccttgattt aacaaggttt tcgtctaata tatcgcacct tttttcgttt
     1741 cttttagcgt acatttttct tcgattgaaa ggccagtcag taagacttct tttctggaac
     1801 gcggccattg aaggtaccca ctttcaaatc ttttgtacat taatacaaat ccattttgat
     1861 cctagtaaag agccttgaag cgatctttct tcgtaccgca aaataagaaa agcgcttgat
     1921 cgtaaacatc aaggtcatat tcttctataa cgaaagctgc tagtccatca attccttttc
     1981 gaagatctgt ttttccacaa acgataaaaa tatgtttcaa tgcagttgca tcaatgagca
     2041 ttggcattca actcttttaa caaggtatac aaaagatatt tatccattcc attataaata
     2101 aatatttcct tatcttccga tttgattctg caagctagtt ttggcttggt gtcaatttgc
     2161 gatttttgag ccgcacttga aaattgaact ggtacaatat cttttttatt cattcgtttt
     2221 tctccttcta tatttgatag tttaattata gaagaaagat aatcggcgta cgagatacta
     2281 tcctatgaca cgcttacatt taatttaata ttttgcctca aattagccac actttttata
     2341 gaactaagag gaaaaatgaa gttttcttcc tattaatata gttgtttgaa atcttaaata
     2401 tagcgtttta cgatgtaatg ggaagtatgg tgaataaatc aactatgttc gtacgaagca
     2461 tttactcaac taatttaatc gaatctttca ataaacaaat caagaaatac agccaccgca
     2521 aggaacagtt ccaaaatgaa gagtcgatgg aacgtttctt agtctcgtct tttgatactt
     2581 acaaccaaaa attcctaggt cgcagtcata aaggtttcca acaggccgaa ggcgagctcg
     2641 aacaaatgct gagtcaaccg atggagaatt agaaacaatc tacagtaggg aagaaccatt
     2701 gacacaaaat tattgacgct cccaactaaa agtgtcaaaa taatgatgaa atcatttagt
     2761 tcttataaat tagaaaagag aaaataaata ttccatatct actttattgg atccgtaaca
     2821 tgactaaatt ctgaatactt tttaaagctt atcatttggt aaaactgaat ataagttaat
     2881 tatatagact gaaaattttg aattttcaga atagaataac ttaaaagtac tgacaaaatt
     2941 ttttaaaggg gcaatattaa tgttctgaga taatcaaatc ctaccgaaaa tatcaaaaat
     3001 ccaatgtgac acaatcagat tgtgtctcat tcgagggaat cacacaatcc cacgtggctc
     3061 taggcagaat tgaatttttg cttggggctt tttccttata ttgattttga atgagactta
     3121 ttatatgtta taatgcaatt aagtatcatt ggagagggcg aagaaaatga agacggtaga
     3181 acctattcga gacaaaaaaa agatcgatgc gatgaaggca atcttggctt cgggaaaata
     3241 tggccaacga aatttggttc ttttttcgat tgggatcaac accgcctatc gcatttctga
     3301 tttgcgtcaa ttgaagctgg ccgacgtgct ggaaatttca cgcggtcgcg tggtggtcaa
     3361 agatcgatta gcgatgaagg aacaaaaaac agctaaacat aattcggtct atatttccaa
     3421 caaattgcga aaaacgattt tggagtacgt tcaacaggaa tttcctgatc aactccttca
     3481 gcaagatttt gacggttatt tgttccctag tcgaaaaggg acgaatgaac cgctcaaccg
     3541 ccaaagtctg tggcgaatca ttcatgatgc tggcacggca atcggattga aagacattgg
     3601 cccacattcc atgcgaaaaa cgttcggtta ctttctctat aaacagggga ccaaaacaga
     3661 aatcattcag tccttgttga accattcttc tcagcgcgaa acattgcggt atattggtat
     3721 tacacaagaa gacaaagata cagctgtaaa aagcttagat ttataatata aaagttaagt
     3781 ttaaacatgg atagttttaa attagtagat tgagtgttgg gaggaaagaa tgagtacatt
     3841 atatattata ggaaacggtt ttgatttaag tcatggttta aaaactagat acactgattt
     3901 ttcaaaatgg gttgaaaaaa gtcatagtga aatattcgat aaaatagaca caatgataaa
     3961 tgaaaataat gaggtgagaa gtacagctga tgataagata ggttggttta attttgaaag
     4021 tagtttgcat gagttaattc aaagtccagt ctttgaagat tatgtagaag agtctaagga
     4081 ttatctcata ggttatggac atgaagattg gtcagattct gcccatcatg attttcaaaa
     4141 tatggtttat gattatgttg tttctctaga agaattacaa caacttttca aggaatggat
     4201 acgcaaagaa atacagccga caatagaaca taaaattcca aaataccaat tttcgtccga
     4261 tgtactattc tttacattca attatacaga tgttttggaa attctataca agcaaccgaa
     4321 agaaaacata tatcatattc atggcagtta tgacgatata ataatcggcc actccgagaa
     4381 ttttgacaac tttataggag a
//
LOCUS       DARPZJ010000115         4382 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.122, whole genome shotgun sequence.
ACCESSION   DARPZJ010000115 DARPZJ010000000
VERSION     DARPZJ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.122"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(306..836)
                     /locus_tag="SLE23_002775"
     CDS             complement(306..836)
                     /locus_tag="SLE23_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8469601.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1018..1674)
                     /locus_tag="SLE23_002776"
     CDS             complement(1018..1674)
                     /locus_tag="SLE23_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEI8469602.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1801..2274)
                     /gene="dfrF"
                     /locus_tag="SLE23_002777"
     CDS             complement(1801..2274)
                     /gene="dfrF"
                     /locus_tag="SLE23_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HEI8469603.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2693..2911)
                     /locus_tag="SLE23_002778"
                     /pseudo
     CDS             complement(2693..2911)
                     /locus_tag="SLE23_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2942..4156)
                     /locus_tag="SLE23_002779"
     CDS             complement(2942..4156)
                     /locus_tag="SLE23_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HEI8469604.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1340 a          932 c          645 g         1465 t
ORIGIN      
        1 gaaatcaact gtctttctca tatttactat tcaattttca tagtgatata ggtacaattt
       61 atatcactac tgtaaaaatg gggttttgcc ttataaatac agcgttttcc gcttgttagt
      121 gtatagtgtt tcttgttttt tgtgcccccc ttgttagata acgggggctt tgaacggctc
      181 gcaagctcgc cgaaccgccg aagcgaaccg cccccttgca agcatggcgg aaaaatctta
      241 aggattttcc cgccaacgtg gtcggatcgc tccgtcggtt taacagcttt tctgtttctc
      301 tctagttatc tacgcatata aatcaaatcg gttattccgt tataagtctg tgttttacaa
      361 agccttaact ttatttccct gtctatgttg cccaaaagac gaaccccatt tcctaacaga
      421 gtaggaataa cagaaatgta atatttatca atcatatttt tgcttaccaa ctgctgaaca
      481 agatttgctc cgccacaaat ccaaatatcc tttcctgctt cttgttttag ccgttccaat
      541 aataaaacag gattttcact tgtaaaatga atttgttggg aagaattgca ctctttatgt
      601 gttaatacat aagttgtaaa tttattatat acccattctt gcggagaaag ttcagtaaca
      661 acctgatgag aagtattcca ccccattaag acagtatcta tatctttggt aaattctgta
      721 taagtgtcga tgttttcatt gtcatttcca tgaccattta gccaagctac tccaccatta
      781 ccgtccgcaa tatatccgtc aaggctcatg gcaataaata aaactacttt tctcattttt
      841 tctcttttat aaatacaaac aggaatttat ttctcttttt tactcataag ggaacaactg
      901 attgctacaa ataaacccat taaaatccat ggaaatgctg ctcttataaa atcactaacc
      961 atactttatt cctccttaaa ttccaatttc cttagttcta caaactgaaa tttttgccta
     1021 tgaatgtatc ttgttcttta tacgcaaaca ggcttctgtg tgcataatcc aatgtcttga
     1081 aaacggcatt tgaattagtc cacaaatatc tttattacac caataatcaa tcagccaaat
     1141 tgctttttca ttgtcgttta ctacattcaa cgattctaag tatccttttc tttctttcgg
     1201 tatttttctt ttcaattcat cataagataa ccgttcaagc attttctcag tgctttccca
     1261 tacttcgaaa atatataaat ataattcttc cagattaagc tgttttgaaa agtctgcaat
     1321 ctgctgtttc atgagttcat ttcctgttgt aatgataggt gaattgatac gctcttgata
     1381 attgcctgca aaaaatactt gttcatcttc atttatcact gtatgcacaa ctatatcttc
     1441 aatgcggaaa atatgccaaa tagaataagc aatcgtctta ctatgataac catcagcgtt
     1501 tatgaagggg attgagttaa aatcttctct gcataattct tctttgaaag atactaaggt
     1561 ttgtattaac tgacttcgta aagtaagtaa agtatcaata cccctcttat aagtatcttt
     1621 cttttttatt tgtgcctgca ttgttttatt aagttcagac cattccttat tcatattcaa
     1681 tcctctctca aattctgatt ttatcgcccc atacaaactg gaatttgtct tacaacaatt
     1741 tatatatgca taaaaagcaa tatatttatg aaaacaccct aaatccaaaa tttactcaat
     1801 tcattttttc cttacataaa atgttctcgt atatttcact tcctcaccaa gtgtttcccc
     1861 tatcaaaact tcaaaatcat tgatatcaaa ttctggaaag aatgtatctc catcttcaat
     1921 atttaaatct acttctgtga tatacatttt atctactatt tgcaaagctt ccttaaatag
     1981 tccatatcca ccagatatgt atacatctcg tcctttagcc aataataatg catcttctaa
     2041 tgatttaact gaaactaaat tatctccttg atactctgtt gtggtggaaa caacaatatt
     2101 cattctatta ggcaacggat gaccgatttc ttcataagac tttcgcccca taataaccac
     2161 attacccgtt gttaactctc taaattgctt ttgttctccc tttattttcc atggtatatt
     2221 accattcttg cctataacat tattctttga cctcgcaaca atcaaaccta tcatctattt
     2281 catcctccat aatatgatgt cgtacctgtg attccatcaa gtgcaccaca tcttaacaaa
     2341 ctcaaaatta tctcgaacta accagctcga caaattcctt ttttgtcttc atctgcatta
     2401 tatcatattg ttataagcat tgccatttct tttctgcttt tgaaaagtta cttatcagcc
     2461 tatgttttgt aaagggtgat attcagcatt tctcacgcaa caagcccttg acaaaccata
     2521 gactaataag ttttaaggta atcaagcaga aatgaaatag tctgctgttt cacggcaaca
     2581 aaaaagagat accaacacac ttatgtagta tctcttagtc tagtagcaat attcttttgt
     2641 ttgcaagcag gtaaacatgg gctgtttctt aatatctttt tgtttgggaa acaccttttt
     2701 cccatccttt caccgttgcc atctctgctg cgcacaatgc cacagggata aaccatagca
     2761 aaccgcctaa taacaagaaa aatactaagc tgaagcctga ggtcgcgaat gtgggatatt
     2821 catataatga aacgaccatt gagatggtca tagccaaaaa gccaaagaac gttaattttt
     2881 ttgcaggaat tttcgttttg ctttgttgca tgaatcttcc tcttttctat ttgaatttgt
     2941 ttcaattgag tttgttgcca aagaagaaaa agtccaatcc ttcttcttgt tcttcttttg
     3001 tagtagtgat cgttgtaaag tgcatcgccg attttaaaat cactgttgtc agcacatagg
     3061 catacacggc agtaatgatg acaccaatca cttgaatccc taagaagtac cagctgcttg
     3121 gattcgttag taaatggctg ttagatgcaa agatccctat cagaatcgta cctgtgaatc
     3181 cgcccatgcc atgaacaccc cacacatcaa gtgcatcatc ccattgtttc tttttacgaa
     3241 aatcaacagc agcatgacag acgatacccg caatgatccc aatcagcatg gcactttttg
     3301 cttctacata accggcacaa ggcgtaatgg ctgccaatcc agcaacggat cctgttagta
     3361 cgtcgacaaa atcaaagcca tttcctttta cttttgcaat gatcagccaa gtaatcatcg
     3421 caaatgcaag agcgatgaat gttgaaccaa atgcattgac tgcttgttca tctgctcgaa
     3481 gtgcaccacc ggaattaaaa ccgaaccagc caaaccaaag cagtcctgta ccgatagcag
     3541 ctgccataag actgctatgc tgacttcttt ctcctaaagg aatctttctt tgaccaagtg
     3601 tgaggataca tgctaaagag ccgaatccag ctgtcgtgtg gatgactgct ccaccagcga
     3661 aatctctaaa tcccatctga tccaaaaatc cgccacccca tatccagtgg caaacaggga
     3721 aataaatcag cagattccaa aaaataacaa gtataatata gccttttaaa ttcaatctcc
     3781 ctgcaaaagc tcctgtcatc aaaggaacgg taatcacgat aaacatcagt tggtaaagaa
     3841 agaacattaa aaatggaatc gttgcaccat gaaacatgtt ggggaagctt gtaacatgtc
     3901 tcatcaaaaa gaaatctgcc gggtttccaa taacaccgcc gatatcccgt ccaaaggcca
     3961 atccgaatcc accaaatacc cacataatcg ttgttatccc aacggagaga aaagattgag
     4021 acatgatcgt tagtatatta ttcttccgtg ctaatccgcc gtaaaaaaaa gctagaccag
     4081 gagtcatcag gcaaaccatt gctgtacata aaatcatgaa tgctgtatct cctgtattga
     4141 taggtaatgt attcattttt ttcgcctcct ttctacgatt acgagtataa aagaaggtgt
     4201 agttgttttt ttcttctgtt tttttgaatt aatacttgca tttataaaag acagacaatt
     4261 aataaaagct tgatgtgttg tgctcttttt cgtttttcac acaaataaag acaaaaaata
     4321 aacggtcttc tttttataga aaaccgttta ttttcgtctt tttttatttt taaagatatt
     4381 tt
//
LOCUS       DARPZJ010000116         4178 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.123, whole genome shotgun sequence.
ACCESSION   DARPZJ010000116 DARPZJ010000000
VERSION     DARPZJ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.123"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            134..1327
                     /locus_tag="SLE23_002780"
     CDS             134..1327
                     /locus_tag="SLE23_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEI8469605.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            1320..3047
                     /locus_tag="SLE23_002781"
     CDS             1320..3047
                     /locus_tag="SLE23_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEI8469606.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            3441..3638
                     /locus_tag="SLE23_002782"
     CDS             3441..3638
                     /locus_tag="SLE23_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HEI8469607.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            3640..3951
                     /locus_tag="SLE23_002783"
     CDS             3640..3951
                     /locus_tag="SLE23_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEI8469608.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            4055..>4178
                     /locus_tag="SLE23_002784"
     CDS             4055..>4178
                     /locus_tag="SLE23_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HEI8469609.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
BASE COUNT         1459 a          645 c          897 g         1177 t
ORIGIN      
        1 atttagccaa gtttttttca gtttggacaa gcaaatttct ttcatttttg acaaagtgac
       61 tacatgatgt taacatagtg tggtcacttt tttcagaaag aaaaatgaat ttacataaaa
      121 aaggagaatt tgtttggtaa aagtagaagt aaaacattta acaaagatat ttggtaaaaa
      181 gacacaagcc gctttagata tgatgaatga tcaccagccg aaaacggaga ttttaaagaa
      241 aaccggtgca acggttggtg tgtatgacgt gaattttgac gtaaaagaag gagaaatctt
      301 cgtgatcatg gggctttccg ggagtgggaa atccacattg atccgtctat tgaatcgtct
      361 gattgagcca acttcgggca gtatctatat tgatggagaa gatgtatcga agttaagcaa
      421 agaagaattg cgagaagtcc gtcgtcataa aatcaatatg gttttccaaa acttcggtct
      481 gtttccacat cgaacgatct tggaaaatac agaatacggg ttagaagtcc gtggtgtacc
      541 taaagaagaa cgacaagaaa aagcagaaaa agcattagaa aattctagtt tgctttcatt
      601 taaagaccaa tatcctagtc agttatctgg tgggatgcaa caacgggttg gcctagccag
      661 agctttagca aatgatcctg agatcttgct gatggacgaa gcgttctcgg ctcttgatcc
      721 gctgatccgg cgagaaatgc aagacgaatt actggacctg caagccaatg ttcaaaaaac
      781 gattattttc attacccatg atttgaatga agctttacgg attggggaca gaatcgcctt
      841 gatgaaagac ggcgaaatca tgcagatcgg aacaggtgaa gaaatattga ccaatccagc
      901 aaatgattat gtacgtgaat ttgtggaaga agtcgatcgt tccaaagtgc ttacggctca
      961 aaacatcatg gtacctgcat tgacgacgaa tatcgaatct gatggaccaa acgttgcatt
     1021 gacaaggatg cgtaatgaag aagtcagcat gctgatggct gttgacagaa agagacacct
     1081 gaaagggatc atcactgcag atcaagcgtt agaagctagg aagcaaaaac gtccattgat
     1141 cgacttccta gatgaaaatg tgacggtgat tgggaaagac atggtggtaa gtgatatttt
     1201 caatattatt tatgactcac cgactccact tgcagttgta gaggatggaa aattaaaagg
     1261 tgtcgtcatc cgaggtagtg tgattgaagc attagcagaa acaagcgagg tgagtgaaca
     1321 tgaataatct attgaactat caattaccag tggcaaactg ggtagaaaat atcacagaat
     1381 ggtttacgac aactttttct ggcctatttt catttttaca aacgattgga caggcagtga
     1441 tgtcggggat tacaaattta ctgttagtga ttccagctcc tttgtttatc ttgttattga
     1501 cggtagcagc tttctttatt tctaagaaac gtccaggact tacgttgttc acattaatcg
     1561 gtctatggtt tatttataac caaggtctat ggaatgattt gatgaatact gtcacacttg
     1621 ttcttttatc tagtgtgatc tcgatcatca ttggggtacc attagggatc ttgatggcaa
     1681 aaagcagtaa agcccaaagt attatcaaac cgatccttga ctttatgcag acaatgccag
     1741 gattcgttta tttgattcca gcagttgcat ttttcggtat cgggatggtt ccaggggtat
     1801 ttgcctcagt catctttgct ctgccaccaa ccgttcgttt tacgaattta gggattcgac
     1861 aagttcctaa agaattagta gaagcttctg attcattcgg gagcacaagt cgtcaaaaac
     1921 tattcaaact agaattgcct ttagctaaaa gtacgatcat ggcagggatc aatcaaacaa
     1981 caatgctgtc actttcaatg gtcgttattg cctctatgat cggtgcaccc ggcttaggac
     2041 gcggcgtatt atcagcattg caaagagcac aagtcgggaa tggatttgtc aacggggttg
     2101 cattagttat cttagcaatc atcattgacc gttttacaca gcatttgaac cagccaaaca
     2161 ataaaaaagc tgcaggagca acaacacaga aaagtaaaaa acgtcaagga ctgatcattg
     2221 gtgctgtagt agtagtgatc ttaggtgcga ttggtatagg gagtttttca tctgccaaag
     2281 aaacaaaacg tatcaactta tcttatgttg aatgggatac agaagttgct tcaacaaatg
     2341 tagtcggtga agtattgaaa caaatgggct atgatgtaac gatgacgcca ttagataatt
     2401 caatcatgtg gaaatctgtt tcaaatggcg agtcagatgc catggtttca gcttggctac
     2461 ctaaaactca tggttcacaa tatgcacaat ataaagatca agtcgaagac ctaggtgcca
     2521 atttgacagg agcaaaagtt ggtttagcag tgccagccta catggatgta aattcgatcg
     2581 atgagttaac cgatcaggca ggtaagaaaa tcataggaat cgagccagga gctggtgtag
     2641 ttacggctgc tgaaaacacg atccaaaaat atgacaactt gaaagactgg aaagtagaga
     2701 catcttcttc aggagcaatg accgttgcac taggtcaagc gatcaaaaaa cacgaaccaa
     2761 ttgtagttac aggatggaca cctcattgga tgtttgccaa atatgatctg aaatacttag
     2821 aagatcctga aaacggaatg ggaagcgaag agcagatcca tacgatggtt cgaaaaggat
     2881 tgaaagaaga ccagccagaa gcttacaaag tattagacaa tttccattgg tcagaaaaag
     2941 atatggaaaa agttatgttg gaaatcaaca atggaaaaga tccacagcaa gcagcaaaag
     3001 actggatcaa agagaaccaa gaattagtcg aaagctggaa aaaataaaaa gacagacacg
     3061 aaataaatgg agcttccaaa attggatcaa atatccaaat ttggaagctc catgttcgtc
     3121 tctatctttt ttgtctataa aaaaagagaa tgcgtagctc atcttcgaaa cgttcaaaga
     3181 cgccgacaaa ctattatgaa tttatgggtg cgagtcaaag agatcgatcg taggtatgaa
     3241 agactaatgt gattaaagtt tattatgtac gaagtgcatt ctcaaaaaat attaaagaat
     3301 atacatagtt tatatactta aaagtgatta aattcttatt caggaattat tttgctacgt
     3361 ttcaagaagg aattgttttt tgaaatttaa tgaatgttag aataatagtc taaaaacatt
     3421 aatttagggg tgattagatt atgaaacatt taaaaatttt gtctattaaa gagacacaac
     3481 ttatctatgg gggtaccact catagtggaa aatattatgg aaatggagtg tattgcacta
     3541 aaaataaatg tacggtcgat tgggccaagg caactacttg tattgcagga atgtctatag
     3601 gtggtttttt aggtggagca attccaggga agtgctaaaa tgaaaaaaaa tgctaagcaa
     3661 attgttcatg aattatataa tgatatatct ataagtaaag atcctaaata ttctgatatt
     3721 cttgaggttt tacaaaaggt atatttaaaa ttagaaaaac aaaaatatga attagatccc
     3781 agtcctttaa taaatagatt ggtgaattat ctatatttta ctgcttatac taataaaata
     3841 agattcactg aatatcaaga ggaattaata agaaatttga gtgaaattgg aagaactgct
     3901 ggaataaatg gtttatatcg agcagattat ggagataaat ctcaatttta atgatactta
     3961 taatattaaa tatgtctcaa aattttttga ttagaaaaat aggtatattg aatcagtgac
     4021 ataaaagtat ttatagtttg tagggggaat cgtaatggaa gaaaaaaata gactaaatgc
     4081 taaacaatgt tcagatcaag agcttaaaaa aattaaagga ggtgctggaa caaaacctca
     4141 aggaaaaccg gcatcaaatt tagtggaatg tgtttttt
//
LOCUS       DARPZJ010000117         4157 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.124, whole genome shotgun sequence.
ACCESSION   DARPZJ010000117 DARPZJ010000000
VERSION     DARPZJ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.124"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            179..775
                     /locus_tag="SLE23_002785"
     CDS             179..775
                     /locus_tag="SLE23_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEI8469610.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="SLE23_002786"
     CDS             899..2698
                     /locus_tag="SLE23_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEI8469611.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="SLE23_002787"
     CDS             complement(2976..3188)
                     /locus_tag="SLE23_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469612.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="SLE23_002788"
     CDS             3650..3799
                     /locus_tag="SLE23_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469613.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="SLE23_002789"
     CDS             complement(4052..>4157)
                     /locus_tag="SLE23_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8469614.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          706 c          729 g         1494 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca tttcaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DARPZJ010000118         4112 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.125, whole genome shotgun sequence.
ACCESSION   DARPZJ010000118 DARPZJ010000000
VERSION     DARPZJ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.125"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(39..281)
                     /locus_tag="SLE23_002790"
     CDS             complement(39..281)
                     /locus_tag="SLE23_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEI8469615.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(313..870)
                     /locus_tag="SLE23_002791"
     CDS             complement(313..870)
                     /locus_tag="SLE23_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEI8469616.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(883..1071)
                     /locus_tag="SLE23_002792"
     CDS             complement(883..1071)
                     /locus_tag="SLE23_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEI8469617.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="SLE23_002793"
     CDS             complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="SLE23_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEI8469618.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2067..2240
                     /locus_tag="SLE23_002794"
     CDS             2067..2240
                     /locus_tag="SLE23_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469619.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2880..3353
                     /locus_tag="SLE23_002795"
     CDS             2880..3353
                     /locus_tag="SLE23_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HEI8469620.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3362..3589
                     /locus_tag="SLE23_002796"
     CDS             3362..3589
                     /locus_tag="SLE23_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8469621.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1234 a          740 c          617 g         1521 t
ORIGIN      
        1 ttgttcttca tttcaacata agtttttctt caatttgctt ataatttacg tgcaaagaat
       61 gaaacgacta atactaaaat gattgcaccg atcaatgatg gaatgatagc cattcctgca
      121 attgttggtc cccaagttcc tagtaaagct tgtccaattg ctgaacctac taaaccagca
      181 atgatgtttg cgatgatccc cattgatgat cctttattcg tgattgctcc tgcaattgct
      241 ccaatgatac cgccgacgat taatgcccaa ataaatccca ttttaaattc ctcctaactg
      301 acttcttact tcttattgta cacgtggttc gttattttct ttgacttttt gtgcaccttt
      361 gcctacagca gattttgctt tatctgtttg gcgtgaagca aattgtcctg tggattttgc
      421 tgcttctgtt actttgtctt gtactgtttc ttgatctttt tggtattctt cttgtgtttt
      481 gatgtctgca acattcacat tcacttcgat aacatctaaa tgtgtcatat tgtttacttc
      541 agtactgatc aattctttga tttggttgta aatatcttcg atgtctttac cgtattctac
      601 gatcacatct agatccacag ctacttgttt cttacctact tctgtattga tacctgctgt
      661 tacgttatct gtgttgacta atttttcagc catatttgag aaaaatccgc catctaatgt
      721 caatagacca tctacatctt tcaatgcata accgatgatt ttttggatga ctttgtcttc
      781 ataagtcaat tcaccattca tcatgcggtt ttctcctttt tcatttgcca aaactgatcc
      841 atttgttgta ttcatgtttt tgttttccat ctttgtttcc tcctatgatt taaaaaattg
      901 atcaactatt cctgactgtt tcaaataaaa accgattcct gcgccaattg ctgtcatgat
      961 tatgatcaac aatgtcttga aaaatccaat cgttaaccat aaaacagcta gcagtagtcc
     1021 aagaccccca aagataatag ggagcttgta tgctgaaaat agttctttca ttatttggcc
     1081 ctcctattcc actcgagagt gcttgtagtc tcttgtatct tcttgttctt cataaccgct
     1141 gtatgtgact gccactttga ccgtttcttt tgttccgagt actttagtta cttcttcttc
     1201 gatatcttgc atcaatacac ctgttttccc tactaatgaa gaagttcgtt tcaagtctcc
     1261 gttgacatgg atatggattc gatttttcgt tgaacgtatc cgtactttag gtgaatgaat
     1321 gaactcttct tcgtgtaaat gggaacgtac caacccttcg atcgcttttt tgtcgattgt
     1381 tagtttgcca tcttcccgtt tcataacgaa agttcctctt gactttggat agaaaagaac
     1441 gactagcaag atgataatag caagaacggc aaatactaca gctgcccaga aaatatattg
     1501 ttgcatgtag taattcgtta aagtaaagaa gcgaaatcgt tccaattgtt caggcataat
     1561 atacggcgca ttgatcaacg caatcgctag aaatactgaa agtagcagta aactcatgat
     1621 aacaccgatt atttttaacc ccttattcat tttccacctc ctataaactt atttttaccc
     1681 tgtaaataac tctaccgaca atcacagtat agatagcgaa cagttagcat agcatcagta
     1741 aataaagcgc taccaaacat tgctggatca taacggcgtt ttattgccag tctgatactg
     1801 aaataacaat tgcttactta ttctctattt acttttgatt gctggctata cttaaaggat
     1861 attattcaag attaaaaatt gcaaagatta tgctcagtta ttattacaag attctattta
     1921 tttattaaat tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc
     1981 gttcttactt tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc
     2041 ttataaataa aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa
     2101 cgattggcta tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat
     2161 tcagttggac tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac
     2221 aaaattatcg aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta
     2281 tggtactttt tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac
     2341 ttttgattta taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga
     2401 tagtaccacc ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata
     2461 aaggacaaat aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa
     2521 taaacatgaa cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct
     2581 catacagttc tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta
     2641 ttgtccaata taatcccagg catctaaact agcattatag aagagacaca catagaatct
     2701 aaaataactg gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac
     2761 cttcatactc tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag
     2821 ttgttttaca ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa
     2881 tgaaatttaa aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt
     2941 tgttcggcgt acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt
     3001 ggcagaccac attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg
     3061 cttatttctt attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa
     3121 gcttaaacat actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg
     3181 gcttacttcc taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg
     3241 taggaatcgc tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa
     3301 aactgcttga acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga
     3361 catggcaatt atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga
     3421 attgagtgag aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc
     3481 aaaagccatc cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg
     3541 tgatttgttg acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga
     3601 acaaacagta aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt
     3661 acgtctatta ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat
     3721 gtactgactc atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca
     3781 actggtttcc tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca
     3841 ccagactgat agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt
     3901 tcataccttg aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat
     3961 tcttttttag taagctccca tatatactgt aaagccttct atatattatg tcatgttgct
     4021 ttttaacatt tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct
     4081 tttttatttt taacattatt ttgataataa tg
//
LOCUS       DARPZJ010000119         3873 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.126, whole genome shotgun sequence.
ACCESSION   DARPZJ010000119 DARPZJ010000000
VERSION     DARPZJ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.126"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(717..3866)
                     /locus_tag="SLE23_002797"
     CDS             complement(717..3866)
                     /locus_tag="SLE23_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEI8469622.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYNTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          799 c          636 g         1362 t
ORIGIN      
        1 gactaataca ggtagtcctc ttttttgtta ttttgatatt ctaaatcatt ttttattgga
       61 ttattccctt gttcgatata gacccaaatt gatctatcaa taattatcaa actgagtcat
      121 atagagacaa aaatttcaaa aatgacctgt taaatggtca tcgaatatca tttaaaatca
      181 atacgacgga gtcagacacg gagtcaaaac aagcccgctg agagtaaaaa atatatacag
      241 tcccataggt aaagtgccac aggactgtat atttttttat ttgagattac ctgaaatgat
      301 tccatttact ttttatctca ttttttccta ctagttagta tcaaatactc tcctattttc
      361 tcaataaact attttgggtt acatggtatc tgaaacagct aaaaccttgt cattacagca
      421 aaaaatcact ttatctccgt ttcatttcag atacatttca cttaagcgga ttccaaaaaa
      481 acaaaagaaa aaggaacccc tagttagcct atgcttttta ttggttcctc tcaaaacacg
      541 gtcatataac aacggggtgg ggtaaatgaa tgaaaaaggt ggaggaaaca ttattcaata
      601 gctgtcttaa atacttcgtt ataaaatgtg aacaaataaa agacatctat ccctattttc
      661 tacacttcca ctttactacc atctttgaat cgtacaattt tcttaactct tctcgtttac
      721 ctcaattcat tttcaagtgg aatcagctca tcatctaaca ttttacgcca tgctcgcttc
      781 atttcttgtg ggtatttaaa tggcttcgct tctggatggt tggctttata tccttcgtaa
      841 tccttactgt tgataattgc tttcatatta ggaattggat cttcacctgg catatattgc
      901 agattagaag catgtaattc tttctcagaa acaaaccact cattggaaaa gacatgaatc
      961 aaatcatcac tcgcttgtgt aaaatagcga cgtttaatga caaagatatc ttcattacta
     1021 tctaaagtcc ccacatcaaa cgcatttaaa atttgtcggt aaacttcttt gactccttct
     1081 gttttattca atttagccaa agctttttca atttcttctc gtgcatctga actattcgcc
     1141 gcataagttc ctagtaattg atcaatataa gtagaatcaa tatcatacaa cttcgtggta
     1201 ttttcactat aaaattcgat cgtggaaaaa tcttctccct ctttttctgg ttcttcctct
     1261 attaatgaac ccttcacggt ctcgtacacg ccaatttgtt cttccaaaag ttgaatttga
     1321 ttgttcaagg ttgaagattt caccatgtca tcattgtaat cgtcataagt cactaacgat
     1381 tcataagcac gattcaattc ttggaatgct ttgacgtact cgatacggat ttcaagtggc
     1441 gtatgttcat caatggattc catggatgaa acctctttta acttaccata tgcttgcttg
     1501 aatctttttt tggattcctg ataacttgga taaatcaaac ccgattcttc ttttgcttct
     1561 gaatacagtt ttgtcgcatc ctcgacattc ttctccattg tggctggctt tcggaaagta
     1621 acaattagtc cttttgtttt ttctggatac gtacggttcg tacgtgaaaa agcttggatc
     1681 aatcctgcat actctagatt acgatccaca aatagggttt gaatcgtagg tgcgtcaaaa
     1741 cctgtcaata gacgatccac tacgatcact aaatcaattt gtttcccaaa ttgtttgaat
     1801 tccgctcttt ttcgtgccaa acgattattg atgtctccgt tataacgctc aatgtctgct
     1861 aatgaccagg aagtattata atactgatta tattcctcaa taattttttg catttcttct
     1921 tgttggacac ttgaatctcg gctgttttct tctaatgaat aggtaatagc gattcgtgga
     1981 aaatcaggat cctccatcgt tcttccttca cgaatgggct gattaggaaa ctcttttgtt
     2041 aaccagtcag gttctttcgt catttctttg atcgctcgat aatacttttt ggccatgtca
     2101 atggaactcg tggttaagat cgcagacttc gttggacggc catttcgaaa atcaaatttt
     2161 gtataggcat tgtctggacg gaacatttta tgaatgactt tttggatatg ttcatctgct
     2221 tcaaaaacag tagggtccaa ataactttct tttttgacag gctccatttg atcaatcata
     2281 cgattgatct gttccggtga atactctgca tatgtttcta cttcttttaa tttccgatag
     2341 attttattct ctaatgaagt cggctccacg gtgttttcat gctctacttg aaatcctaaa
     2401 accgagccat cttctaatgc attcttgatg gtataggtat gcaagacctc tccatactga
     2461 tcatgggtcg tacgtgccaa ttgccctttg gcttgtttcc gattctcagg gaaaatcggt
     2521 gtacctgtaa agccaaacca agtggatttc ggaaacattt ttttgatttc ttccatattt
     2581 tcagcactta acgctcgatg acactcatct actacaaaca cgatatgttg ccccattaat
     2641 ttttggaagc gattggttcc ttttttctct tcttgttttt ttgcatattt caacgccgca
     2701 tctagctttt gacgggttgt aataatcaca acatttgcat tggcatctgc caacagagtt
     2761 tcacttaact ctttggcact tcctgttccc acgatcaagc tattcgcttt ggcgttcccg
     2821 gaagaaatcc cagtattaaa ttccgaagca aatttcgtaa actctgtggt ggtttgatta
     2881 tctaaatctt tgcggtccac taacatgatc gtccgatcga tccccgattt tcgtgctaaa
     2941 agcttagtag atacaaaact agtcaacgtt tttcctgaac cagtcgcatg ccacacatat
     3001 cctgattgat gtttatttgc agcaataaac aaggcttgaa tcgcatgtac ttgataagga
     3061 tgtaacacca tgaggatttt attgtcttga tcttcactga caatcgtata atccgcaatc
     3121 aagcgatgag catccgggat atttagcact tgtttgcaaa actcatataa gttttctacc
     3181 tttttattat ctttcgttcg ccaactaaat aaaaacttag gatgcaaatc ctttggtaag
     3241 gcatttgcaa aataccgagt ggtttgttca ttggaaacca caaacaactg taaggtcgaa
     3301 aagatattgt tccgaaacat accttcttct gcatattttt tgatttggtt aaacgcctga
     3361 taaaaactat cttttgcggt tacttgtttc agctcgattt ggacaatcgg taatccattg
     3421 atcagtaagg tgacgtcaaa acgtcgatcc cgtgcttcta tgttacttcc acgttttgca
     3481 atttgatgga ccacttcata ggtagagatt cctccaccaa tgtcttgatt agaataaaga
     3541 atgagcgaga cagaacccag ttgcggatct tcccgttcaa tcgtgatccg agccattcca
     3601 ttttcacctt ttaaccattt cgcagcatca aagggggttt tcgttcgtag taacaattct
     3661 gttttgatcg tttcaaattc tttatcggtc aaaggaaaat cattcagttc tgcttgatta
     3721 tttgagatga ttttttggcg taaattgacc caaagatctt cttctgattt tagatcggga
     3781 cgatacgtcc actgattatg cccttccccc aatacacgga tcaactgttc ttcgacttcc
     3841 gcttcctcac ggtgactaat tttcatttat ctt
//
LOCUS       DARPZJ010000120         3735 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.127, whole genome shotgun sequence.
ACCESSION   DARPZJ010000120 DARPZJ010000000
VERSION     DARPZJ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.127"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            11..478
                     /locus_tag="SLE23_002798"
     CDS             11..478
                     /locus_tag="SLE23_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469623.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="SLE23_002799"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="SLE23_002799"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HEI8469624.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="SLE23_002800"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="SLE23_002800"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEI8469625.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..3697
                     /locus_tag="SLE23_002801"
     CDS             3200..3697
                     /locus_tag="SLE23_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEI8469626.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT         1230 a          596 c          807 g         1102 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat gaaatcgatc aagcatttct agaaaaatat gtagatcttt tattagcaaa
     3661 ttttaatata aatgcttttt catttattaa taactaaaat cgtctattga aacaaaaaag
     3721 aagagaaatc aagaa
//
LOCUS       DARPZJ010000121         3697 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.128, whole genome shotgun sequence.
ACCESSION   DARPZJ010000121 DARPZJ010000000
VERSION     DARPZJ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.128"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(222..1307)
                     /locus_tag="SLE23_002802"
     CDS             complement(222..1307)
                     /locus_tag="SLE23_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEI8469627.1"
                     /translation="MSTENQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSETIDKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHKAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            complement(1627..2034)
                     /locus_tag="SLE23_002803"
     CDS             complement(1627..2034)
                     /locus_tag="SLE23_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469628.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     RNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            complement(2053..2871)
                     /locus_tag="SLE23_002804"
     CDS             complement(2053..2871)
                     /locus_tag="SLE23_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEI8469629.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
     gene            complement(3097..3390)
                     /locus_tag="SLE23_002805"
     CDS             complement(3097..3390)
                     /locus_tag="SLE23_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEI8469630.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSMNMTDVYEKLLILENEYDQFNSNQQRKVKKQID"
     gene            complement(3402..3581)
                     /locus_tag="SLE23_002806"
     CDS             complement(3402..3581)
                     /locus_tag="SLE23_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469631.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQLISMNPFLFLQIGVDTRI
                     MRVLNYYCKRNNKRK"
BASE COUNT         1110 a          588 c          514 g         1485 t
ORIGIN      
        1 tacatatgca aacactagtt ccctgttttt ttgaatgaaa aataactaaa atatctaacg
       61 attatgacat taaaacctac gtttgtgatt gttttcataa acttttaatc taaaaactcc
      121 ggaataataa ctatttattt gtaacatttg taataaaatt aaaattgtaa aaaagttcta
      181 atttaaaatt gatcattttt atagtgttcg ctttttatca actactctag ccaattttcc
      241 gtactaactg ttggtaattc gttaaatgtt tctctttgtt cgtttgcaag ctttgccgca
      301 atagcttttt caataaacca gttttttaca tacacaaaaa tcaaattctg caaattattt
      361 actttctcag tcttttgttt ttgataagct ttcagcaacg tcatatataa tcctttatcc
      421 gcatcaattc cgtaagattc aagttcttca tacacaacta ccgtcttctc aagttcctcg
      481 gctttatgtt ttgctttgtg tattgtggtg acggtttgtt gggcttcttc gtaagtgtta
      541 gaaaatgttt ttatcaagct taataccttt tctggtacaa atgtgtttat gctgtcttct
      601 ttcatgattt caacgaagtt atctagcaaa acttgatttt gtaattggtc tgtttcagtg
      661 tcttttaagt gtcttttagt gtctaaagat ttattaatat aataatcttg tgcgatttcc
      721 gcatttccag tgttatcaag ggtttcagct gttttttctc gacgtgcgat ttccgcattt
      781 ccagtgttat caagggtttt agcagtttcc tctcgacgtg cgatttccgc attccgagaa
      841 gaggttgatt tatcaatagt ttcgcttaaa tcgtcatcga aagaattttg aataaaaaga
      901 tcatcggcac ttatttcagg ttgaagtaaa tagtatttat ttttttcatt ttttttcgtt
      961 tttgggttaa attctccttt tacgactgaa atcaaattat atgtttctaa ctcgtttaaa
     1021 atggttttta ctttgccttg gtagcaattt aatttgtcca ttaggtctgc ttgtgtaaat
     1081 tccaaatata atagaccatc atcgtcgatc catttttcat gtaaggctct acgaaattca
     1141 tttttaaaaa gcatataggc tatttttgag ctgtctttca ttttagagta tttagaattc
     1201 tgaattaaaa aactaggaaa tttataatat ttttcaatat aaacattcgt tgctttatat
     1261 ccccaatttt taattatcat tttttgagat tgattttctg tagacattaa atttctcctt
     1321 cttcttagaa acttgtatat attcaggatt ttcaacaagt gaactatacc atgtattaag
     1381 ggtgaataaa acactttcag tatttaaggt ataagttata tattaaaaaa ataagtataa
     1441 gttatacttt aaatacaaat aatgtataac ttatacttta aataataatt ttataatgtt
     1501 gatttaatcg caaatttaca cgttgtttat taagttatac cttaaatatt taatgtataa
     1561 cttatacttt aatattcatt tatctagtat aacttatact ttaattgaat accgcatgaa
     1621 aaaaaattat tttggtaatt tttcaaactc ttcttgtatt tcttctctta tgtgttcttc
     1681 ttttgctact cctagtctat gctggatata tgagtctgct aatgtattaa caattttttc
     1741 gaaagaaatt ctcccttttt cactttgtaa ctccgtcata tagtcttgta aaattgagag
     1801 tttgctattt aatgccggag agatcttttt aggaactgat accttgtttc ttttatcagg
     1861 aattgaaact ggtcggcctc tttttttcaa tgtaatattt cttgtgttac tcaatgcact
     1921 attgctaaag ttatattcac cgcttatttt cacatcttgg cgtttgttat tgggtaataa
     1981 tggctcaaat tcaccattct ccatcatttt aggaatatca aaatctttag gcattactta
     2041 tgcaactcct tattatttat ttaaaaactc ttgtctagca tctagttctg ccaaaatatt
     2101 tataaatact tggtgtgctt tataatccca ttgatcaaaa tttccatttt tgtattttct
     2161 taaatgtata ccaattttag aataccttct caatcttttt tgataatgaa tgagattttt
     2221 ggataccacg gttccgtatt tttcaattgc ttcttctagg atttcttcat caaaatcatc
     2281 atttggttct accatacaag gtacaatatc tataatttgc aaatcaagat cgtatctatc
     2341 gaccatgaat ttttgataat ttacatattt gttgactccc tctaaggatt cttcagctgt
     2401 ttgaaatgaa attatcgaat agtctgaagc tgccatagca ttatcggaaa attcgctaat
     2461 ggttggtggt acatcaataa atatttcttg ataattgttc tttattggaa gaagtaattt
     2521 tttcaagaca gtaacttggt ctaattcatt ttcatgttta ttagcaaaag cggagaatga
     2581 tcgaaaacta gtgtcacatg ccagaaggtc aagattttca tttaccttaa taatactact
     2641 tgctaattct ccatttgcga caccatttgt tatagtggtt ttgatatcgg ttataccgaa
     2701 agttcttgct atgacttgtg ttaagttcgc ttgagggtct aaatcaataa taagcgtttt
     2761 tctatttctt atcattgcat tgtcataagc aagcatgctg actatcttag ttttacctac
     2821 tcctccttta aaattgccaa ctgtaaatgt agtcccttga aaagtatcca tgtaaatcct
     2881 cccaatcttt aattgataat taaagtataa cttatatatc ggaaatggtc aacattaaaa
     2941 gtataactta aataataata tctaaaaacg tttggatata gcggttttta ataataaaag
     3001 tataagttat accatatata tttatggtat aacttatact tttattatta aaggtataac
     3061 ttatacctta aatattgctt ttcgaaaata gctattctag tctatctgtt tctttacttt
     3121 tcgctgctga tttgaattga attgatcata ttcattttct agtattaata acttttcgta
     3181 tacatcggtc atattcatac tagaagcaag acttagatca tatacaaatg aagcaggtaa
     3241 tgattttatt ctacgttgtc gggttatcca gcttgcaacc gttccttgtg ggtaggcata
     3301 taactcacaa aattgttcta cagtgattcc taaattcttg ataatgtaaa cattgatcgg
     3361 gtgcgagtaa acaaatgtat tgatagacat ggtgcgtaag cctactttct tttattattg
     3421 cgtttgcaat aatagtttaa cacacgcatt attctagtat ctactcctat ttgtaaaaac
     3481 aaaaaaggat tcatagagat aagttggcca taaccccaaa tctcttctga tagctgatca
     3541 aaggttatat actttagctc atattgctgg ataatgttca ttctaatcga ctccatttat
     3601 tatcctggta aaattcgata tgacgtattt cgtcgtagtg aattttgtct tttccaacgt
     3661 agatccccag ctcatcacta cctaagatct tgccaac
//
LOCUS       DARPZJ010000122         3655 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.129, whole genome shotgun sequence.
ACCESSION   DARPZJ010000122 DARPZJ010000000
VERSION     DARPZJ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.129"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            116..976
                     /locus_tag="SLE23_002807"
     CDS             116..976
                     /locus_tag="SLE23_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HEI8469632.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            988..1815
                     /gene="panB"
                     /locus_tag="SLE23_002808"
     CDS             988..1815
                     /gene="panB"
                     /locus_tag="SLE23_002808"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HEI8469633.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1830..2678
                     /locus_tag="SLE23_002809"
     CDS             1830..2678
                     /locus_tag="SLE23_002809"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HEI8469634.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2688..3083
                     /locus_tag="SLE23_002810"
     CDS             2688..3083
                     /locus_tag="SLE23_002810"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HEI8469635.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            3285..3655
                     /locus_tag="SLE23_002811"
                     /pseudo
     CDS             3285..3655
                     /locus_tag="SLE23_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1425 a          412 c          722 g         1096 t
ORIGIN      
        1 gatattatga taaattaact atggatgata tttgaaaaaa acatactgta tatttgattt
       61 aatttttatt tttaagctca tatcgtaaga atgggacttg tagtctcact tctttatgga
      121 ggtgataatt atgaacgttg gttttattgg agccggcaag gtaggttgtt cattcgggaa
      181 gtatttccag gaacataaaa tacaagtaac aggattttat agtaaaagcg aagactcgtc
      241 attagcagct tcgaatttta catctagtaa acaatattta aacttaagag aattagtaga
      301 tgaaaatgat actattttca ttacgactcc tgatggtcaa attcaggagg tatggcaaga
      361 aattaaaaat tatcaaatca aaaacaaatt aatctgccat tgcagtggtg caatatcttc
      421 agatatcttt tcaaatatac aggactatgg tgcttatggc tattctgtcc atcctatgtt
      481 ttcaatatca gataaatata attcatacaa aaaattaaaa aaatctttta taacaattga
      541 aggcgatgaa aaatatgcaa agtttttatg tgatttcttc aaaaagttag gtaatagtac
      601 tgtaattgta tctaaggaga ataaatctct ttatcatgcc gcatcagtag tatctagtaa
      661 ccttgtgcta ggacttatta atacaagcgt tacatatcta attcaatgtg gatttactga
      721 aaaaatggca attgaagctt tatatccatt aattgaattt aatattagaa atataaaaga
      781 aaaaggaatt atagaaagtt tgacagggcc agttgaacgt tgtgatattt caacaattaa
      841 aggtcactgt gaagttttat cagatgaaga cagagcttta tatatgctat tatcaaaaaa
      901 tgtattagag atagctatgt taaaaaatat taatagagat tatagtgaat tagaaaagta
      961 tttaggagag agttaggaga gaaatagatg aaaaatacag cagttacatt taaagaatct
     1021 aaattaagaa atgaaaaatt aacaatgctt acagcttatg actattcaac agcaaaaata
     1081 attgatgaag ctgggataaa tggaatatta gtaggagatt ctcttggtat ggtatgtcta
     1141 ggacatgaag atacactttc agtaacaatg gaagacatga ttcatcatac tagagcagtt
     1201 acaagaggag ctaagaacac tttagttgtt gcagatatgc catttatgtc ttatcaaact
     1261 tcagtatatg attcagtagt taatgcagga agattaataa aagaaggacg agctcaggtt
     1321 gttaaattag aaggagggat agaagtatgc gataaaatag aggctatagt aaaggcttct
     1381 atacctgtta tggcgcatat aggtttaaca cctcaatctg ttaatgcatt tggaggattt
     1441 aaggtacaag gaaaggacaa ggaagctgct aaagaattaa taagagctgc taaagctgta
     1501 gaaaaagcag gagcattcgc tgtagtgtta gaatgtgttc caactaagct tgcagagtta
     1561 atttctaaag agatatcaat acctacaatt ggtattggag caggtgcagg gtgtgatgga
     1621 caaattcttg tatatcaaga tatgttgggg atgtatagtg attttacccc taaatttgtg
     1681 aagaaatatg ctaatttatc agaagagatg aataaagcat ttacaaaata tatagaggaa
     1741 gtaaaagatg gagtttttcc aggtccagaa catgggttta aaataagtga tgatgtttta
     1801 gaaaaattat attaaaaggg tcaagaaata tggttatatt taaaacagtg aatgatgtta
     1861 gaagtcaagt aaaagagtgg aaaaaacaag gcttaaaggt aggattagtt cctactatgg
     1921 gatatttaca tgaaggtcat gaaagtttaa ttagaaaagc atcaaaagaa aatgataaag
     1981 ttgttgtaag tatctttgta aatccaactc agtttgggaa aaatgaagat ttaggtagtt
     2041 atccaagaga cttagaaaga gatatagaag tatgcacaag aggtagagca acagcaatat
     2101 ttaatcctga agttgaagag atgtattgtg acaatgcaag tacttttgtt aatataactg
     2161 gattaacaga aggtttatgt ggagctagta ggccaataca ttttagaggg gtttgcactg
     2221 ttgtaagtaa attatttaac ataataccag cagatagagc ttattttgga gaaaaggatg
     2281 cacaacagtt agctgtaatt aaaagaatgg ttagggacct taatattgat atagacgttg
     2341 tagggtgtcc aattataagg gaagaggatg gactagctaa aagttctaga aacacatact
     2401 taagtttaga ggaaagatct tcagctacta ttttaaataa atctttaact ttagctaagg
     2461 aagctttaaa taatggagag agagacagct taaaaataat tgagataata agtaaaaata
     2521 taaatactta taatttggca aagattgatt atgtagaagt tgttgattct ttatcattac
     2581 aaagagtaaa ttatattgaa aaatcagttt tagttgcaat agcagtattt ataggaaaaa
     2641 caagattaat agataatttt acatttgaat tacaataggg ggctataatg aaagttacaa
     2701 tgttaaaagg aaaaatacat agagctacag ttgaacaagc tgagttagat tatgtaggaa
     2761 gtattactgt tgatatgaat ttattagaag cagcaggaat atatgaatat gaaaaagtac
     2821 aaatagttga tgttaataat ggaaatagat ttgaaactta tacaatagct ggagagagag
     2881 gaacagggat gatttgcttg aatggagctg cagctagatg tgtatcaact ggagataaaa
     2941 taattttaat ggcatattgt gaattaaatg aaaatgaggt taaggatcat agacctaagg
     3001 ttgtttttgt cgatgataat aataaagttg aaagagtaac atcatatgaa aaacatggaa
     3061 ggttatcaga tataattctt taggttttgt aatgttattt atatatagct agactattat
     3121 tgaaatattt attgattact aattggatag atgtcaataa agtagacaca aaaagagaag
     3181 atacagactg tagacaaagt ccattttatg tgaatcggct acactagact agacagaaaa
     3241 aataaggtgt gtagaataat aaaaaacaca ctggaggatt tttcatgtca agacgtcaac
     3301 gaagaaccta ttcaaaagaa ttcaaacaac aaatcgtcaa tctctatctc gctggtaagc
     3361 ctcgcgcaga aattattcga gagtatgagc ttacgccttc ttctttcgat aaatggatga
     3421 agcaagcaca atcaacgggc tcattcaaaa aaagagacaa cttaacacca gaacaagcag
     3481 aattgatcgc actaagaaag aaaaataagc aactcgaaat ggagaatgat attttaaagc
     3541 aagcggcgct gatattcgga cgaaaagaca agtaattgat gccaacaagc ataaatattc
     3601 catatcagcg atgtgcaaaa ttctaaatat ttctcgtcag acctactatt atcaa
//
LOCUS       DARPZJ010000123         3534 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.130, whole genome shotgun sequence.
ACCESSION   DARPZJ010000123 DARPZJ010000000
VERSION     DARPZJ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.130"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(184..741)
                     /locus_tag="SLE23_002812"
     CDS             complement(184..741)
                     /locus_tag="SLE23_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469636.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(920..1531)
                     /locus_tag="SLE23_002813"
     CDS             complement(920..1531)
                     /locus_tag="SLE23_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469637.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSARYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(1644..1901)
                     /locus_tag="SLE23_002814"
     CDS             complement(1644..1901)
                     /locus_tag="SLE23_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469638.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2498..2776)
                     /locus_tag="SLE23_002815"
     CDS             complement(2498..2776)
                     /locus_tag="SLE23_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469639.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(2810..3061)
                     /locus_tag="SLE23_002816"
     CDS             complement(2810..3061)
                     /locus_tag="SLE23_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469640.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1078 a          725 c          470 g         1261 t
ORIGIN      
        1 atttgccact ttgattcgta taaagctaac aactattaac tcctctcagc taatagttgc
       61 tctctttttt attcagattc atttttgctg atcacagcct agtatttcaa tggttttgaa
      121 cactaaacca aattgttcca ttacaacatt cactggctga tgaaatggat tagtagattt
      181 cgattattca aagcgatttt ctattggtgg atcgtgttcc caactaataa gacggattcc
      241 aaacctatcg tacagatctt ctaaaccact tataaatttt gcacctattt caggtgtttt
      301 attgcgtgga tattctattg ttacgccatt aaatggatac caattaggat taggctctct
      361 ttttttctgt acatctccca tagaatagtt agcactttct gggacataat atattcttcg
      421 accatcctct aattcatcta ataagatatt tcgtgatcgt ctatcacttg ctaaatgtag
      481 acgccacgtg cgataccatg ccatgctacc tgcatctgca gaaaatccat caaataatgc
      541 aacaattgta tcttctatca caatcctttc cccatctact tcatattcta atctaaaatc
      601 aaactcccct cgggtaattt ctggtcttgg tggcttagga cccaatatta ttctacttaa
      661 aaccgcattc gttcccagat gaaacacagc tataacaaca ataatgatta atattttgtt
      721 tctatttgat aaatttctca ttattcgcac atcacctcta cattctcaca tattagttcg
      781 taatactcct ttaatatcaa aatatctact ggtcgtaata atattcgcta tgaattccta
      841 ctactcgtat aagaaaggcc aaatcatcag cttttacttg ctgatgattt ggcttgtttc
      901 tatttatcgt aattgttttc taatcaccaa aattgttaac aatcggttca gatatttccc
      961 agttgattaa ggtaattccg tattgtgtca aaacttcttg cgcttctccg aaattaagta
     1021 cagttcttat gtatccactt tctcctaata taaagtctac ctctctttta aaaccttcct
     1081 cgagatttct aagggctata tgtggtttta atgacattga ttgtacattt tcccccatat
     1141 aatatcgcgc acttcctcga ctaaaataga ttcctagatc gtccccaaaa ggtagatctt
     1201 ctctaccact agctaatcta cttctccatc ttcgttctct tttcatagaa cctgcgctga
     1261 actcacaccc gttaaactca gctatgacag tatcttcaat tatgttaatc tgtccatcta
     1321 gttcgtattc aatcctaaat ggaaattctc cataggtgat ttccggttcg ggtattttag
     1381 gtgagattaa tgcaaagaaa ggaaatatta agcttggcaa catcaaaaaa actcctccta
     1441 tgatcacaat tcccgatgta atccaaaata taatttgtac aattctcatt gatccattgt
     1501 attccatttt attcccccta ttactattca tatccgccta tctatatcga tcttccaatg
     1561 cagagataat tgcttccata ccttgatttt ttactgagtt acctatgcga gatatcattc
     1621 tccactaagg tgcatcatat tgtctatcta acatgattaa ttctccaata ggtgtatact
     1681 cctccaaaaa caacatttaa tgcatctccc tcgacaacat aagctaccat gtttgctgta
     1741 tatgtgtttg agtctaattc ataagcagat aaatttactg tcgctggatt aaatataatc
     1801 gcattcgtat ttatagctac tgaatttgct gcttcagcac caccttttga atgtccgatc
     1861 attgtgattt caatagtagg atttacgtgg acagccctca ccgtttaccc tgaccattat
     1921 agaaatcgct tacttttttg aactacgcaa caaaggatac aatgctccta acttcactgt
     1981 ctccattttt gtccactaag gaatataaaa aataggcatt aattcattta attcggtcac
     2041 aacacgttac cttttaaatc attatactgt atctcataca ttattatcaa taaactatta
     2101 taaaaatgca aaaaatgctt tatcaatcta ttttgtaatt ggtcataata tcattgaaat
     2161 cataccctgt atcgattttt cctatgaatc tcgtctattt gtgattgacg aaaaagaggc
     2221 aagacagaca ctggaatggt aattttaccc actattttgc tccaactatt tgtaatcgta
     2281 cccacttttg aaataccgag atgatcattt taattgatat gctgattccc aagcaaaacc
     2341 ccaagaaatt aaatgctcta tcgcatctag cttcttgggt tttgcttata taaattccaa
     2401 catttaaatt ttttatgctg ttcggtctca gaaatgccgt ttttgcttat atcacaatat
     2461 caagatgtca aattattcgt gttgccgatg actttgatta atttttttca aattgtttat
     2521 taagactaat gctgtctttt tgcagatacc aatgttcgaa ctttttaaca ttatcatatg
     2581 atcctgcaag ttttaacttc ttaccattag atgttatcaa agttataatt aaccttgcct
     2641 ttttcccatt aggatctttt attttatgaa ttttctgcag gtaatctctc ctaatggcag
     2701 ctatttttac ctcatcagtg ctgataaacc attgatcatc cacatacata ctgcctgtta
     2761 tgttgtgttt ttccatttct tccgagaacg aaaagtttaa ggctcgttct tacttccaaa
     2821 gttgaatgag tccatggatt ggacttagtg tgagaattga gaacaacaat aagaatccat
     2881 atcctcccgc aaacatccct aaggctatac tgtctctcca tccataagta ggattagaag
     2941 agaaaagagt caccgtttgt aataatatga aaaggaataa tccagcacaa acaccaaaga
     3001 taacaactcc aaacattgaa tttttataca atgaccattt atttataggc ttttctttca
     3061 ttttacttcc ccctactgtt ctgttcacac ggaatgaatt caaagttcat aagccctcct
     3121 ctttgaacat atgaatacga cttgctaact atactttaaa aaagcttgtt ttaagcggtt
     3181 ataggcgagt tgtaatctct attcatctca ttagcaaata acttgccgaa aagtctactg
     3241 aaattaaagc agatagtgga agaattattt agccaggata gacactattt gtgaaacaca
     3301 tgtctttact tttgaaattc tatgatgaaa agccttggaa tacagtagct cttaattggt
     3361 aatacttttt ccattataaa taacctcttt tcattttata tttatcccct ctaaaaataa
     3421 tatctaatct aatattttaa acttatattt ccctcgctgt gctaatagag cattactaaa
     3481 taaatagaaa ctagaaaaaa gcattacgcc tgccagaata aaccaattat ttgt
//
LOCUS       DARPZJ010000124         3274 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.131, whole genome shotgun sequence.
ACCESSION   DARPZJ010000124 DARPZJ010000000
VERSION     DARPZJ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.131"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(368..1486)
                     /locus_tag="SLE23_002817"
     CDS             complement(368..1486)
                     /locus_tag="SLE23_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469641.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1957..3264
                     /locus_tag="SLE23_002818"
     CDS             1957..3264
                     /locus_tag="SLE23_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEI8469642.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         1026 a          679 c          589 g          980 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aata
//
LOCUS       DARPZJ010000125         3252 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.132, whole genome shotgun sequence.
ACCESSION   DARPZJ010000125 DARPZJ010000000
VERSION     DARPZJ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.132"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            3..587
                     /locus_tag="SLE23_002819"
     CDS             3..587
                     /locus_tag="SLE23_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEI8469643.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(664..1857)
                     /locus_tag="SLE23_002820"
     CDS             complement(664..1857)
                     /locus_tag="SLE23_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEI8469644.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1921..2301
                     /locus_tag="SLE23_002821"
     CDS             1921..2301
                     /locus_tag="SLE23_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEI8469645.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2375..2737
                     /locus_tag="SLE23_002822"
     CDS             2375..2737
                     /locus_tag="SLE23_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469646.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1102 a          528 c          615 g         1007 t
ORIGIN      
        1 atatggcatt cccacaacta gatttaaaaa gtgaaaaagg accaaaagct gttatcaaaa
       61 caaaccgtgg tgacattact gttcaattat tccctgaact agcaccgaag acggttcaaa
      121 atttcattga actttccaaa aaaggttatt atgatggcgt gatttttcac cgcgttattc
      181 ctgatttcat gatccaaggc ggcgatccaa ctggaacagg aatgggtggc gaaagtattt
      241 atggcgaaag ttttgaagat gaattcagtc gtgaactgtt caaccttcgc ggagctttat
      301 ctatggcaaa ttcaggtcca aacacaaacg gaagccaatt ctttattgta aataacacaa
      361 atgtgccagc taatatgctt ggacaactag aaggtgctgg attcccatca gaaatcattg
      421 aagcgtataa aggtggcgga actccttggc tagatttccg acatacagtc tttggacatg
      481 tactagaagg gatggacaca gtagatgaaa tcgcaaatgt acaacgtggt ccacaagacc
      541 gacctgtaca tgatgtagtg attgaaacaa ttgaaatttc agaatagttt ggtatggtac
      601 ggagtaatta tgaaaaagga cgaaacctag taaggtctcg tccttttatt ttgaataaat
      661 gatttaatcg attgtctcta aagcatactt gattcgatta agtccttcca gtaaagtttc
      721 ttctggacaa gcaatattca agcgcatatg cccatgaccg gaaggaccaa acgtgatgcc
      781 aggatttaat acgacttttc ctttccgaac aagagtgttc tccaattctt ggtcgtctga
      841 aatataggcg gtaaaatcta accacattaa gtaagttcct tcagggttca ttattctcac
      901 tttcggaaga tactgttcaa aaaactgatt aactgtttga acattttttt ctagataagg
      961 aatcagttgg cttaaccatt ctccacccgt ctcataagcc gcttgggttc caatcagtcc
     1021 aaaagtgttg atttcgtgct gttggttcat cactaaatgt ttttcaaaat cagctttcat
     1081 ctctggattt ttgataaata ccattgaatt tttgattgca gctagattga aagtcttggt
     1141 tgcggaagta aaagcaacta gtagatcatc taaattagga tcaatcgtta gcatggaagt
     1201 aaatgtatga tcgaataaag ttaaatcttg atggatctcg tcactaaaca gaatcacttg
     1261 atgttttaaa cacaattcgc ttaactgttt caattcttct ttgctccaaa cacgccctcc
     1321 aggattgtga ggattgcata aaatcattgc ttttacattg ttttcttcga tttttttctc
     1381 catgtcagac aagtccatga tgaaatgatt atttttttct agcaaagagc ttcgaacgat
     1441 gtgacgttga tttgtttcta taatagagga aaatggagga taaactgggt catgaatcaa
     1501 aatagaatcg cctggttttg taaaagtttg tactgctgca gctaaactgg ttaacacacc
     1561 acttgtaaaa acgatatttt ctttcgtcaa ctccacagca tggtgttggc gttcccaatg
     1621 aatgatagcc tgatatagtt tatcagacag agtggcataa ccaaagattc catgtttgat
     1681 gtattcacta aacgctttag ctaccccacc gggagacaag aagtccatat ctgctaccca
     1741 caaaggaagt aagtcatcca tttgatatgt ctcagcaatt gcgtcccatt ttacactttc
     1801 tgtatctttt cttgaaatct gtttatcaaa ttcgatcatc ttaagacctc cagtcatttt
     1861 cgtcgcttct ttttttgagc tatttacagt ataatgataa atgcgaagag agggaagtag
     1921 atgacttata aaattggaca aataattgaa ggaaaagtga cagggataca gccttatggc
     1981 gcattcgttt ctcttgataa cgagacgcaa ggacttattc atgtttcaga agtacaatcc
     2041 ggttatacga aaaatatcca ttcattgtta aaagtcggac agccagtaac agttcagatc
     2101 atcgacattg atgaatattc caaaaaaatc agtttatctt taagaacgtt agaaaaaaca
     2161 aatccagctg ttccatatcg cagaaaaagg tatttcacga ataaaaatcg taagatcgga
     2221 tttaccacta ttgcggagca gttacctatt tggatagaag aagcattatc tgaactagaa
     2281 cggaaagaaa ataagaaata aaaagtgtat tttttctgaa aatgtgctag aatttttatg
     2341 taagccatag aacaagttga tcgaggtgga aattttggca agcaaaagag ttgctggtac
     2401 aattatgttg catttggagg atggtactaa aaaatttttg gtccattcaa ttgatgacaa
     2461 gttggaattt gcgttagcgg aactttctga aggaaagact ggtttagcga atatacttaa
     2521 tttcttaaaa gaaatagttc atatcgatgt tagcaagatt agtttgatgg aattgacaaa
     2581 tacacatatt aaagaggaaa atgttccgtt gtttgtcttt gaaactgaac aaaagaatca
     2641 aagagaagaa ttaggcgaag gatatatttg ggaagaacca ggtcaaatgc gctctgttct
     2701 tggaacttac gaagtagagg gagtgccttt cttctaaaat acagattaag cgaacaaaga
     2761 agtttgaatt tttttcaaac ttcttttttt attgtttggt ccaaaaaata caatgaaatg
     2821 ttctgctaaa gatagttttt tagtgcattt tattttcaaa atatgttgaa aacggttgta
     2881 taacgaataa taataattga tcgaaaaatc atttcacaaa gtaatgctta atttatagtt
     2941 gaccaaggaa gaaatacatg ataaatttaa cagcgttgat tctgaagtgg atgttatatc
     3001 acatttctaa aaaatttaaa aaatagttat tgacatgtta ctaacgacat gataagataa
     3061 ctgagtcgtt aaaaaagaac cacttgcgaa gcttgattct atcgaaaaaa acttcaaaaa
     3121 agttcttgac aaataacaaa cgataagtta tgataaatga gttgctgaaa gatttcgaaa
     3181 aacgaaatcg aaaaaaactt ttaaaaaaga gttgacaatc gtttgtctct ctgatatgat
     3241 ataaaagttg ct
//
LOCUS       DARPZJ010000126         3221 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.133, whole genome shotgun sequence.
ACCESSION   DARPZJ010000126 DARPZJ010000000
VERSION     DARPZJ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.133"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            50..1438
                     /locus_tag="SLE23_002823"
     CDS             50..1438
                     /locus_tag="SLE23_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HEI8469647.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3221
                     /locus_tag="SLE23_002824"
     CDS             1776..>3221
                     /locus_tag="SLE23_002824"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEI8469648.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEEE"
BASE COUNT         1185 a          505 c          583 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaaga a
//
LOCUS       DARPZJ010000127         3194 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.134, whole genome shotgun sequence.
ACCESSION   DARPZJ010000127 DARPZJ010000000
VERSION     DARPZJ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.134"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            655..1635
                     /locus_tag="SLE23_002825"
     CDS             655..1635
                     /locus_tag="SLE23_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEI8469649.1"
                     /translation="MAKKKQDLINGTFREKKRNLKKIMAFGDGRISGKTLENMKACGS
                     FMEFIATVDKEKKKMVHGMFCKNRFCPVCAYRKARKDSYMLSIMMEAIQAEKGYEYIF
                     MTLTTPNVPADKLSEEIDRFNKALSKLFRRKRVTTSIKGYVRKLEITYNKSRNDYNPH
                     FHLIMAVPKHYFKMKGYYIKQSEWLDMWRDVTGLDGINEDGTDEICSLDVRKVNGYRQ
                     EKAVSEIAKYSAKDFEITYSQDVFDTFYFAMKGRQLMTFNGVFKEYRKKYESGELDHY
                     KKKDENDYFWFLTASWMQKDANYSVAVRELTDDEKKFFAERYDKEGDETG"
     gene            1745..2107
                     /locus_tag="SLE23_002826"
     CDS             1745..2107
                     /locus_tag="SLE23_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469650.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAEMGKALRKH
                     FGFESFDDFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNESDGLLGVIPSKK
                     SQMSESKFTSMFNDVSLR"
     gene            2329..>3194
                     /locus_tag="SLE23_002827"
     CDS             2329..>3194
                     /locus_tag="SLE23_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEI8469651.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELGYISRQREE
                     NEREKALVASERA"
BASE COUNT         1055 a          498 c          762 g          879 t
ORIGIN      
        1 taaattagag cgttctgaga atgagattga gtggtagcca cgatgtgcag tcaacggtac
       61 cggaggcggt ttgtgccgag gataaggagt tgacggctaa accactagcc tattaagctg
      121 acatttgcta aaaaatggcc agtccatttt ttggccaacc tagcgttagc gaagtttggg
      181 ggcgcccttt tcaaagggtg cggttttatg tttgcatgac taagaatgag tgggaaaaat
      241 taacagcccc ctctaacagg cggttaagtg tcccttttat ggacaccccc ctaaaaattc
      301 agtggtcaat cgatcgaatt ttatgcagaa gtgggttttt gagttttggg gtttgaaacg
      361 agaaaaaaga ggtcgatttc gacctctttt tttgatgttt cttcttatct tgatacatag
      421 ggtaactatt ttcgggagaa aatcgtgccc tatgtatggt cttatccctt gatttataag
      481 gatttataac aaaaaaaagt tgcaattccg atatggttgt tttatgcttt gagtgtctaa
      541 ttcaaaagtc ataattcaac gagaggagtg caaccttttt ttcgtgcatt tagaaaatgc
      601 gttttttaaa tgtttggacg gaactcttgt gttctgtaag gttcagtata gcatatggcg
      661 aagaaaaagc aagatttgat caatggcact ttccgagaaa aaaagagaaa tttaaagaaa
      721 atcatggcgt tcggtgatgg ccgtatttct ggcaaaacct tggaaaacat gaaagcctgt
      781 ggatcattca tggagtttat agcaacggtt gacaaggaga agaaaaagat ggttcatggc
      841 atgttctgta aaaaccgatt ttgtccggtt tgtgcatacc gaaaagcccg taaggacagc
      901 tatatgctgt ctatcatgat ggaagctatc caagctgaaa aggggtatga atatatcttt
      961 atgaccctca ccacacccaa tgtgcctgcg gataaattat ccgaagaaat tgatcgtttc
     1021 aacaaagcgc tgtcgaagct gtttcggcga aaaagggtga caacttcaat caagggctat
     1081 gtccgaaaac tggagataac gtataacaaa agccgaaatg attataaccc gcattttcac
     1141 ttgattatgg cggtacctaa gcattatttc aaaatgaaag gctattatat aaaacagtct
     1201 gaatggctag atatgtggcg ggatgtcacc ggtttggatg gcattaacga ggatggcacc
     1261 gatgaaattt gttcgttgga tgtccgcaag gtcaatgggt accggcaaga aaaggcggta
     1321 tcggaaattg ccaaatattc tgccaaagat tttgaaataa cctattccca agatgttttt
     1381 gacacgttct attttgctat gaaaggtcgt cagctgatga ctttcaatgg cgtgttcaag
     1441 gagtacagga aaaaatacga gagtggcgaa ctcgatcact acaagaaaaa agatgaaaac
     1501 gactatttct ggttcttgac tgctagctgg atgcaaaagg atgccaatta ctcggtggcc
     1561 gttcgtgagt tgacggatga tgagaagaaa ttctttgcgg aacgctatga taaggagggt
     1621 gatgaaactg gataagcaaa ggctatatga agctgaaaaa gaattttggt tgaaattaat
     1681 gagtcatgtt atgcagttaa accaaatttc cgttattaat tccaaagaaa aggggatgta
     1741 gtttatgggg atgactttag cagatattaa agcacaagaa gaaaaattga aaaaagaaca
     1801 ggcaaaactt cgtcaacaga aaaaacgatt gattgagaag gaaaatgctg aaatgggtaa
     1861 ggcacttcgg aagcattttg gatttgaatc ttttgatgat tttgagcggt ggttatcgtc
     1921 aatttctgac gatcagcaac acgaaaaatc agtggataat gagtggcttg ctgatgaaaa
     1981 atcagcgcca agcgaacgag attatcccaa tgaatctgac ggcttactcg gagtgatacc
     2041 gagtaaaaaa agtcagatga gtgagagtaa atttacgtca atgtttaatg acgtgagttt
     2101 acgataagcg attattttgc gtgaagcaaa ataaagcgta aaaggagttg agagcgtgac
     2161 acgctttcgg ctcctttttt cgttgtcact tgtgacagcg aataccctcg gagagcattt
     2221 ggaattgtga cagccatgtc acaattagga aaatgttact ctttgacaaa gagtaacaga
     2281 aaggtttaca ctctttttat tagcgacagc gcgaaggagg ggtttaactt ggggtttagt
     2341 atttcgttca aaaagggaac aaagaataca agcatttctc ataataatcg tgagttaact
     2401 gatagccaaa aaatcaatga ctggcataag catattgatt tcacaaaatc ggatgaaaat
     2461 atctatttgg aacaaataaa tattcgtgaa aaatatgaag aattattcgg tgaagccgta
     2521 gaaaaatata atgcaaagca gaaaagagcc gatagaaaaa tcgaggacta tttagcaaag
     2581 gttcgcaagg ataaaaaaat ggaaccacag cgagaattta tcgtgcaaat tggtactctt
     2641 gatgattttc gtactactcg tgatgatggt tcttctactg gcatatcgga acaacaagca
     2701 gaacaaaatc gagtgattgc caacaaaatt ttagttgagt atttcaaaga atttaaagaa
     2761 cggaatccta gtttatccgt ctacaatgct gttattcata atgacgaagt aagtccgcac
     2821 ctgcatttga atattgttcc tgttgctgaa gggtataaac ggggtgttca aaagcaacca
     2881 agcttcaata aagccttgca acagcagggt ttacgagcag ataaagagaa tggtcgagtg
     2941 atttggaata attttaggaa tcaggaagtt gagtcaattg aacgtttgat ggcagatttt
     3001 ggttgggagc gtgagttagt cggtactaac aaaatcaaag atattcatga atacaaagaa
     3061 atcatgagcg aaatttccga attgcgtcaa acggccgtaa aagagcgtga gagcgtttct
     3121 gatgagttgg ggtatatttc taggcaaaga gaagaaaatg agcgagaaaa ggctctggtg
     3181 gcttctgaga gagc
//
LOCUS       DARPZJ010000128         3167 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.135, whole genome shotgun sequence.
ACCESSION   DARPZJ010000128 DARPZJ010000000
VERSION     DARPZJ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.135"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(64..609)
                     /locus_tag="SLE23_002828"
     CDS             complement(64..609)
                     /locus_tag="SLE23_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEI8469652.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(632..1117)
                     /locus_tag="SLE23_002829"
     CDS             complement(632..1117)
                     /locus_tag="SLE23_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEI8469653.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(1107..1919)
                     /locus_tag="SLE23_002830"
     CDS             complement(1107..1919)
                     /locus_tag="SLE23_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HEI8469654.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(2058..>3167)
                     /locus_tag="SLE23_002831"
     CDS             complement(2058..>3167)
                     /locus_tag="SLE23_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEI8469655.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT          975 a          679 c          567 g          946 t
ORIGIN      
        1 gttaaagttc attagttgga ctttgcgagg aagtttttca gattgctctg tcaattactc
       61 atttcaataa ttcgctctag gaccaccgat atatttagga cgagagcgaa gggctgtcac
      121 gtgagcttgt ccaagggttt tcaaacgagg tctgacaggt acttggacat gtttgatatg
      181 cataccgatt gatgtgtcac cgatatcgat accggcttgt ccaactacgt gttccacttc
      241 gacaggatca ttgaactggt caaaagcagc aacagaacaa gcacctccag catgtagtgc
      301 aggaacaaca gagacaattt cgaaattttt tgcttctgcc actgttcgtt ctactactaa
      361 tgctcggttc aaatgttcac aaccttggac agctagcgca atttctttag gatccaacaa
      421 ctcttttaac gtacggatga tccattgacc aacttccgca ctggaatttt ttccaatatg
      481 tcctccaacg acttcgcttg tgctgcatcc taaaacaaaa agatcacctt ttttcaagtg
      541 tgcctcagcc aatatgtcat taactatttc agtcaattgg tcttttaatt ctttttctga
      601 caacttcatt ttctaaaacc ttctttttca attaatattg cttccgtgct tgaatacgtt
      661 gaagacttgc agttatagga aaggcaagtc ccattccaat cagattttgg aagatgtttc
      721 ctggtataga agccactcca gccggccaat catataaaat ccaaccggcg ataccatagc
      781 cgatgatcat aactaagctt cctaataaaa gccctaatcc ccacatacga gtagaagatt
      841 tgctgaaaga accagcaaca tatccttgta acccgtggat cactaatgaa aaaactgccc
      901 actgcggata tcctgaaatc aaatcgatca atagaccact ggaagcacca acaactaatc
      961 cacccgttgg accataaaga aaagcagcgg tatagatccc ggcctcgcat aatgtcacaa
     1021 atccattcgt agccggtaca gggatcaaaa ttgttaatga aagggcaact gtcaacgcaa
     1081 tcagcatagc atagatcgtt aattgcttag ttttcatttc tcattcctcc tttttgaata
     1141 ccgccagacc agacacttcc ggtatgatcg ttcatcagca cgccattaga aatacaatgg
     1201 gcaacaaatt ttttactttc tgctactgct ttggtaaaat ctgcccctaa cacaagattc
     1261 gctgttattg cagaagaaaa ggcacaaccg gccccgttta ctgttgtagt gtcgattttt
     1321 ttatgagaaa atacctcata atgatcaatt gaatagagaa gatccacagc ttcatctcca
     1381 gccatccttg tgccgccttt gatcacaatg ttttttgttc ctgaagcagt gagttcttta
     1441 gcgagatgga tcatttctgt taacgaagag ggaagagctt gaccagaaag taaagcagct
     1501 tctgccaaat taggcgtaat catcgtaaca agtggaaaaa gttcttcgat gagctgcgaa
     1561 atatacaatt gattgatcac agcttcagtt tctttgaatg ccaaaacagg gtctaaaatg
     1621 attgggatat tttgttttgt ttttatgaag tctcgaacaa ccatgattgc ttcacttgaa
     1681 ttcaataacc caattttgat accatctaat gaagtcattt tatcaatcga aactaactgt
     1741 cgtttaagca attccaaaga tatagattcc agcataaatc gctcattaat atctagtgcc
     1801 cctatagaag tcaaggcgct tagtccgaat agaccaaaat tctcaaaagt ttttaaatct
     1861 gtttggattc ctccaccagc aaatggatca gaaccgccaa ttgtcaagat tcttttcata
     1921 acattttcct ccatgaataa gagtataacg aaattttcaa aaaagaaaaa cagccaattg
     1981 gcatattttt atctcatcca atttaaaaaa acaaaaagaa aagaaagacc aaaatggatc
     2041 tttctttcct taaatagtta ggacttttgt gattttaatt ctttctcgat ttgaagccgt
     2101 tgcactttca ttgtagctgt tcgcgggatt gcatcaaaat cacggatgat agggacgttc
     2161 aagcgaggaa gttcatggac ttgctcccac catcgattcc aatccatttc tttatcagga
     2221 gctaaagcaa taatcggttg tggagaatga tttttatccc ttacaatcac tacttctgcc
     2281 aaaaaatcta acgaatctaa taaaaagtct tcaatagcta atgtactatt gatcgtttcg
     2341 atcaaatcca cttgccgatc tttcaaaaat aggtggccat gcttatccat aaaaccgtaa
     2401 tctccgctat cccaccaatc gccataaaca ttttcctgga accgtgcatc ttccttgtaa
     2461 taagtcaaag cccgtccttt agacagtaat tgtatatgac catctgtgtt ttcaggtagg
     2521 acattcccaa ctgaatctgt aatccgagcg cttgtcatgt cttccagtcc aacgcccata
     2581 tctcttgcat cacttgtttt caaactctct agtgtatgag ccttaagaat cattggtccg
     2641 cattcacttt ggccatatac ttgaagaaat accgcatcct gtgccatcga cgttcgcaaa
     2701 aatgtcttca ttgtctggtt gtttatagca tcaaaagtgg agtgatagta tcggataccc
     2761 gaaaaagctt ctggatgctc cttagcagta aaacgccact gaacaaagtt attcggatgg
     2821 gtctctagtg caattggccg gtgagcttcc aacatatgaa caacttttga actttgtgcg
     2881 tttgctaaag gcatcatagg aaatcccatg gacatcaaag aagagatacc aatattgaat
     2941 ctggaatgca ctggagagat gtgaaaagcg attaatttct tttccgaaat ttttgtgaaa
     3001 actgtttttt gccatttcgt ccgccatccc atagaatgag cagaatgaca aataagttta
     3061 gggataccag ttgtaccaga agtatgggtc atataagaaa tttcattttt gtctaaaaat
     3121 gattgagaaa cagacaaagc aggttgttcc attaaataaa gaatagg
//
LOCUS       DARPZJ010000129         2725 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.136, whole genome shotgun sequence.
ACCESSION   DARPZJ010000129 DARPZJ010000000
VERSION     DARPZJ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.136"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            27..377
                     /locus_tag="SLE23_002832"
     CDS             27..377
                     /locus_tag="SLE23_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEI8469656.1"
                     /translation="MSRLIIQTAFYKAIIPENLDEVKLYLWEDNGEIVGFSGVSAEEL
                     VMLFLDPDFIGKRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLD
                     GFGKPYPITHLVKK"
     gene            791..1609
                     /locus_tag="SLE23_002833"
     CDS             791..1609
                     /locus_tag="SLE23_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEI8469657.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1682..2041)
                     /locus_tag="SLE23_002834"
     CDS             complement(1682..2041)
                     /locus_tag="SLE23_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8469658.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          940 a          379 c          481 g          925 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgttttata
       61 aagcaatcat tcctgagaac ttagatgagg ttaaacttta tttatgggaa gataacggag
      121 aaattgtcgg ttttagtggt gtaagtgcag aagaattagt tatgctattt cttgatccag
      181 attttattgg taagcgatat ggtagtcaaa tattaattga gctgattgaa actgaagata
      241 taaaaagaat tgatgttaat agtcaaaata aatatgcaaa acatttttat ttaagccatg
      301 gatttgaaat tgaatctgaa gaagacttag atggttttgg taaaccatac cctataacgc
      361 atttagtaaa aaaataattc atgaatggtt tattacctga ttgaacatga ataaaagtaa
      421 tatttttatt ttgatggcct atttctaggt tatgaattat ccagatcaaa tttgtgtatt
      481 acattcagta ataaggtgct tatcttagga tcaacttatg atactagctg accaaggatg
      541 taccagttat agaaaatcag ttaaagtaaa aatgataaaa atcttatgtc aacactgatt
      601 taggctgacc tgtgggttag gagaaagaca ggtcggtagc ttttaataca aaaaatggct
      661 tgtatgtatc tagatagtta actgaaatta gaaatgttct tatttttaac ggagtaagaa
      721 aaataggctg ctttaggtct gaatactttt tcaatataat gaagatatca aaggcgacag
      781 gagtgttttt atgaataaga atcctcataa tctaaagttg gtagcagtag atatggatgg
      841 aacatttgct cgtactgatt acacatacga tatcccaagg ttcaaggctg ttttatcgcg
      901 aatgaaagct gttgattgtc aatttgttgt tgcaagtgga aatcaatact accaattgag
      961 atcgttattt ccaaattatt atgatgaatt aagttttgtt gctgaaaatg gtgcttttgt
     1021 taaagataaa acagaggtac tattttcagc cgatatgcct agaaaagcga tcgaggtggt
     1081 ccttgattta tgtaaagact atcctgaagt aaaaaatgtg atgtgtggtc tgaatagtgc
     1141 ctactgtgaa agaggaaagg tgagtcaagc attttttgat ctaaccaata tctattacca
     1201 tagattagaa tgggtagctg attttgcaga agttcaagat aaaattttaa aatttgctcc
     1261 gactatgcct gttgaaaaaa ccgaatttta cgttgaattg ttccgtgaaa aattagccgg
     1321 gctattagta cctaccagta gtggtcatgg ttctgtagac ttgattcttt ctgagtgcca
     1381 taaaactttc ggcttgaaaa tgttagttga gcgcttgggg attaatcctg accagtgcgt
     1441 tgcttttgga gatgggggca atgacattga gatgttggag tattgtggtc tgagttatga
     1501 aatggataat gcaacggaag ctgttaagca agttgctaag catcaatgtc cttcaaatga
     1561 cgaagacggt gttttagtga cgctcgatcg attgttccct aacacgtaaa cactaggtaa
     1621 ttcatcaaaa aacctcgata taagaaatat tcgaggtttt aaaactatat ttagaacaga
     1681 tttacgaagc gtctgatgag tcaaaataga cttggacatt gctatctaaa ataccacttt
     1741 cattctttaa acgaattgtt tgatttgatg gagttacctc taatactaaa tgcccattaa
     1801 taaaggtagt atcgtattca gatgttttaa ctgttgcttc ttcgcaaggt attgttaaat
     1861 catatgctgg aatataatgt tgtgtggaaa ctaataaaaa atgatcacca atcatacagc
     1921 atccctctgc tgaagaaaat tgattagagc catcatttaa agttaacaag aatccatcct
     1981 ttaaacgagg tacttgctta aatacttctg gttgtacttc taaaaataaa ttatcgctca
     2041 ttttcacgac caccatcgac ttccacagtt gaaattgaca ttttatttaa cacacctatt
     2101 cccccttaac tataactcaa ttctatataa aaaatattct attctcaaat aattgaactt
     2161 ttcaaatcgc caatttactt cggctttatc agagctcatt catatcaaga gcgattaacg
     2221 ctgtaaaaat taaaccgaag atctgataaa ttttctctat tttctacaat atttaaaacg
     2281 cttccttagt ctattatata tctatttctc ttaggagtat gtttagatgt ttgaataata
     2341 gttgcccaac tttaaaggtt attcttataa tattttactt cattttccaa tagaaaattc
     2401 aaaggattac tggtttttct aaaatagttt agtttaaata cataagtatc ctccgacact
     2461 gtattagttc ataatcatct aaatacaaaa ttttcaaata aaaatatttc aagctctatc
     2521 gttgacgaat gtaaacgata cttataaagt aatagaaatt gattacattt gtaaacttaa
     2581 aatggttaat ttatctcaca taaaactaag aataaaataa tgattaaaag tggttagttt
     2641 ttatacgatt tagcctatcg gtaaaaatga attagagagt gtaaaatatt ttgtgtaaat
     2701 gaaaaaatcc atacaaaaaa ggaag
//
LOCUS       DARPZJ010000130         2640 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.137, whole genome shotgun sequence.
ACCESSION   DARPZJ010000130 DARPZJ010000000
VERSION     DARPZJ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.137"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            112..1311
                     /locus_tag="SLE23_002835"
     CDS             112..1311
                     /locus_tag="SLE23_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEI8469659.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(1338..2606)
                     /locus_tag="SLE23_002836"
     CDS             complement(1338..2606)
                     /locus_tag="SLE23_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEI8469660.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT          791 a          573 c          469 g          807 t
ORIGIN      
        1 ataagaaaaa catctttcca tcggaaagat gtttttttgc tttttctagt ttaaataaca
       61 gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt tatgaatcta
      121 accagagatc tgatcttttt agttctctat cttattgggg tattctctat cgtttattgg
      181 cgaaaacaga agaaggatcc ttccttgttc ttttacggca gtacgtggac atttacggta
      241 atcttaactt attttgtcgt gttggaaatt ttttattcga ccttttattt tttgattcca
      301 ttgttgttct ttagtatctt tgctttttct tatttcacag aaaaacgaag gctactgaat
      361 ggtcttttat tcaatgtttt actcatcagt ttcggcatct acttgtttgt cttgctgtat
      421 gaaacgcaaa atatttttct tggcggactg atcgccttga tcacgattcc attgctactt
      481 gtccttttat ttggtattta tggattgatt gtttttcttt tttggaacgg ggtcacagtt
      541 ttacgtagag aatcgcattc attagctaat cttttaacgt tgatactagc catttttctt
      601 acactgtttc ttgtttttga ctttttcttg ttaaaatatt tgccgcaatg gataaatgct
      661 ttgtttttct gcgttcccct gatcttgatc tatctattta tcgtattcta caactttttg
      721 actgtctcat tcttgtatca gttcaaccgg cctcgataca atcaagactt catcgttgtg
      781 ttaggcgctg gattgatcaa tggagaaaca gtttctcctc ttctagccaa gcgaatcaat
      841 aaggcaattg ctttttatcg ggctcaaagc cgtgctacat taaatccgcc catcttattg
      901 atgtctggcg ggcaaggagc agacgaaaaa gtaccagagg ccattgcgat gaaacaatat
      961 gccatggaac aaggaatccc tgaaagagac attcttgtcg aaaccaattc gacaaccact
     1021 ttggaaaaca tgctctattc aaaggaaatc atggatcagc aaatgaaagg gccataccgc
     1081 gcgatcttta gttccaacaa ttaccacatt tttagagccg gtctttatgc gcggcaagcc
     1141 aaattgaaag caaatggtat tggtgcaaaa acagctttct actacttgcc taatgcgttt
     1201 ttaagagaat acctcgccat cttgatgatg aacaaaaaaa gacatatgat catttgcgga
     1261 ttgcttttcg caggctccgc attcttatcg ctgattactt tacttttcta aaaaaacaag
     1321 gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac tattggcaaa
     1381 aagagtatcc cttttttgac cgctacttgc tgagcagaat aaataccgct gttgcctgaa
     1441 cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga accgaacaat
     1501 tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa tactccgata
     1561 aagcccaatc ctgcaagaaa aggaacagaa acatggagca aaggcgctag tgctgcacca
     1621 agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc cgcgcctaaa
     1681 gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg tccattaaat
     1741 gattcttgaa gtaacggaag actcaatccg agataacgtt gtgtttgcaa aatcaatgct
     1801 gctgccacaa ctacagctcc acctatcgta tttcgacaaa caggatgagg aatccattgt
     1861 gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat caaaccaaaa
     1921 gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg aatcacaccc
     1981 atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc aaacagtgca
     2041 gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa cacttctaat
     2101 ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc actgattcca
     2161 ctgataatca agatttcccg ttctgattta tccaatcgga acaaacgtgc cgtattatct
     2221 gctaacgctc cccccatttg gactgctgtt ccttcacggc caacagatcc cccaaataaa
     2281 tgggtagtta tggttccaaa cagtgtaagt ggaataagcc gcaacgggat tttttcttct
     2341 ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagtcc gccgtgatac
     2401 gcatagagat aagcaaaaag cgcaccacta actggtagta gacaaaggag ccaaggatgt
     2461 gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga caagctcccc
     2521 atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatatacac taaaatgcgt
     2581 actggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa acgcctacta
//
LOCUS       DARPZJ010000131         2634 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.138, whole genome shotgun sequence.
ACCESSION   DARPZJ010000131 DARPZJ010000000
VERSION     DARPZJ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.138"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            5..1150
                     /locus_tag="SLE23_002837"
     CDS             5..1150
                     /locus_tag="SLE23_002837"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEI8469661.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="SLE23_002838"
     CDS             1321..1779
                     /locus_tag="SLE23_002838"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEI8469662.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="SLE23_002839"
     CDS             1938..2408
                     /locus_tag="SLE23_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEI8469663.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="SLE23_002840"
     rRNA            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="SLE23_002840"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          863 a          504 c          496 g          771 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgccttt
     2461 gcgtggcgac gtcctactct cacaaggggc aacccctcac tacaatcggc gctaagaagc
     2521 ttaacttctg tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt
     2581 ggtgttatct tttattgagt aaattttgtt cactcaaaac tggatttgaa gtca
//
LOCUS       DARPZJ010000132         2630 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.139, whole genome shotgun sequence.
ACCESSION   DARPZJ010000132 DARPZJ010000000
VERSION     DARPZJ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.139"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            1175..1729
                     /locus_tag="SLE23_002841"
     CDS             1175..1729
                     /locus_tag="SLE23_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8469664.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1983..2294
                     /locus_tag="SLE23_002842"
                     /pseudo
     CDS             1983..2294
                     /locus_tag="SLE23_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2405..>2630
                     /locus_tag="SLE23_002843"
     CDS             2405..>2630
                     /locus_tag="SLE23_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEI8469665.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVC"
BASE COUNT         1015 a          309 c          414 g          892 t
ORIGIN      
        1 ggaaaacgta gacgtaattt tctacgtttt ccttttcata tatattaaat attacggaaa
       61 tttatataaa ctaatttagt gttttgtttg taattcctaa ttttgctcca cttttagata
      121 atttttaggt ctatttaact catcagacat tctatgctca ttttctccaa atttgtttca
      181 actctttcgt acttaatttt gcgtatttga aaattcttct tttagagtac ttttattacg
      241 atactagtat gatatatatc tatagcaaac agttaaaatc ttcctaaaat aagcgaatag
      301 cattcctaaa acctataaaa tttttagatg aagcgacaag tggacaatta ataaactact
      361 tgaacatgaa attatggatc acctttcaaa tttagaaaat ggaattctta tacttattgc
      421 gcaacattta ttgattgcaa aattatgtga caaaaagaac tagtagaaga aggaataatg
      481 gcttgataat aaagtactac ctattaaagg tagtacttta tttaatttag tataaattaa
      541 catactacta tattttaagt ttcatattat ataaattaat aatatactac cattttttgg
      601 tagtataatt taaaggtaat aagttattct tttattacta tgtttgggtt ttatagcaag
      661 gaaagtttaa taagagtttg gacctagcaa acaatattaa tgaggtcatt aaatcttatt
      721 atctttagtg atataacgaa atatctacac agacaaaatt atgatcttgc gtaaagttat
      781 aaaatattaa taaaaatatt ttattaatga aaagcttggt agcacggtta ttcatatgct
      841 aatttatttc actttttata gtaaggggag ttcttagtat attgtccaaa tttaaatttc
      901 atataattta attatgtaaa ttagctattc taagaacttc tacggataac tgcccgtcta
      961 aaatttaatt aagagcttag aatcttcata taagtaaggt taattttttt gtacaaaata
     1021 gtcggaatat tctgagttac tgaaatgata taaaatcata aactaaaccc cttgattttc
     1081 ttcactttta acagagtata tatataagtt catgattatg gtaaaatata tatataatca
     1141 tgaactcaga atatttttaa gaagggaaac aatagtgagc tataatgtac aaccgttaag
     1201 gacaaatgaa gagatacaag attttcagtt ttggctaaga agaacaagta atccagaaag
     1261 agatagtttt ttatttttgt ttggaatcaa taatgggtta cgtatgtcag atattatagg
     1321 attaaaagtt ggagacatac gaggtaaaag taagcctatt attgttgaac ataaaacagg
     1381 taagcgaaaa ccgattttta tagataattt gagagaagag attttattat atactgaagg
     1441 taaagaagaa aatgattggt tatttccaag tcggcaacaa ggtcgacata taacaaggga
     1501 tcgtgtctat cagatatatg cagatatagc agaaaaatta ggaagagatg atataggaac
     1561 acatacatta agaaaaactt ttgggtatca ctactacaag aaaactagag acattgctac
     1621 cttaatgttt atttttaatc atagctcgca agcaattaca aaaaggtaca ttggtataac
     1681 tgaagatgaa ataggggcat cgttacgtgg ttttaaattg ggaggctaat tgagatatta
     1741 ggatatattt tttgtgtata atgaaaactt agaaggtgag attaatgaag ataactgaat
     1801 tttcggaagt atttaaaacg tttagtaaca tttacaatag aataccagag atagaacaaa
     1861 atgttgtagt tgataatgat tattatatag agaatgattt taataaacca agaaaatatg
     1921 acaacctata caattttata cacaatagaa caacaataaa taacaacagt aacactcgag
     1981 ttttgattaa ttcagcatat tttcatatta aatatttaaa gaaatatgag tatgaagaag
     2041 ttgtattaga ttatgggcta aatagacagt catttttaat ttatgcaata aataacggaa
     2101 atttgccaag caataaaaag aacataatta ttgaaacata tgcctatctg gaggggggat
     2161 ctaaaaaact aattaagtca tgtaatatag agtatcaatt atcagtagga gaaattaaat
     2221 gtgttttcga agaagattta gaacttgact taaaaaaaat ttttgccagc attcatgatt
     2281 atataggttt gatacccgtg gtgctagtta attttttcct agaggaaaat gtctaaacat
     2341 gttggtaaat caacaaaaaa acgcatatag tagtctcaaa actcccaaga aatgaggact
     2401 acatatgcgt tcatcaaaat atactgaaca ttatacagat acttttataa cattcaagga
     2461 aattatgaga actgtttcta acatatacca caattgtgta ccagataaga ttaaaaaccg
     2521 aagaaatact gatcaactga agcaacgcga tacagtgatt attgcttgtg ttatatgggg
     2581 cataattaat ggctatacta gccaaagagc cacgtataga gcggtttgtt
//
LOCUS       DARPZJ010000133         2618 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.140, whole genome shotgun sequence.
ACCESSION   DARPZJ010000133 DARPZJ010000000
VERSION     DARPZJ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.140"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(493..1785)
                     /locus_tag="SLE23_002844"
     CDS             complement(493..1785)
                     /locus_tag="SLE23_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8469666.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2059..2319)
                     /locus_tag="SLE23_002845"
     CDS             complement(2059..2319)
                     /locus_tag="SLE23_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469667.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          886 a          483 c          398 g          851 t
ORIGIN      
        1 ttatattata aattcacatg attatcgaat tttattaagt tagtttttct tgtaaatctc
       61 tgttcccaat gaaactcgag acacttattt taaagaggaa acaatgtggt atttaaatag
      121 ccctcttgta tgggctactc tgtgatactt attagccatt aaactatttt acccacatag
      181 catatatttt gaaatcgttc attccgtaaa ttcaactaaa tatgcctaaa aaaataaaaa
      241 atctaagata gaataagatt tattcagtct tagatggatt tatagcaact ttttcgtaac
      301 aactttaaaa aatacgaaaa gaaagagctg ttttactctg actacgttgc taaattgtcg
      361 tttaatcatt catttaaacc aaatcttttt ttatagaatt cgttttaatc ctcctgaatc
      421 caaaaactat gaaaaccgta attaaatagt taagagtttt taaccaccat aattctctcg
      481 gctattttga aatcagataa attttgatcg gacacatagt tgaataaacc taccgttgtt
      541 acggaaggta aatcgcatac ttttcattct agaggagaag gtctcgttga tcattaactg
      601 attaagcacc atagcccagt tttgaattcg accacctgac cacttcgcgt gtaattcttt
      661 cgtgcgtaaa taaagtagtt ttaggagtgc attctcatta gagaacgctc ctttttttgt
      721 gacttttctg aagctggagt ggacactttc aaccgcattg gtagtgtaca taatttttcg
      781 aatggcacta ccataatcaa atagttgttc aacatgtgca aagttccgtt tccagacatc
      841 tacagcacca gaataatgag accaccgatt ttgaaaactg tcaaaagcag catgtgcagc
      901 gtttagagaa gaagcaccgt agaacttttt catatctcgg cagacttcct tatagtcctt
      961 acttggaata tagcgcaatg catttcgaac aagatgaaca atacagcgct gaacaattac
     1021 cgatggaaag atcgcttttg cgccttcttc gaggccagaa acaccgtcca tcgaaatgaa
     1081 aaagacatct tcgacaccac gtgctttcag ttcatcaaat acttgcatcc agcgattttt
     1141 agattctgtt tgatttaacc ataatcctaa aatctcctta tttcctttga gatcatagcc
     1201 aagaatggtg tatacagcat attctttggc ttcataattt tctcgtaaag taacatacat
     1261 acaatcaacg aatagaaagg cataacactt tgctaggggg cgggcttgcc attcttccaa
     1321 ttcaggaagg acagcgtcag tgatatctga aatcatttca tgggaaatat caaagccata
     1381 aatagcttcg acggttgcgg caatatctcg ttgactcatt cctcgtgcat acatggaaag
     1441 aaccttccct tcgatgtcgg agacatctcg ttttctctta ggaattaact ctggttcaaa
     1501 ggaagcttcc cggtctctag gaacatcaat agctacttca ccaaaactgg ttttaagcgt
     1561 tttagttcca tagccatttc gacggttatc gtgttcctta ggctctttag aatgggcatc
     1621 ataacctaaa tgattattca attctccttg aagcattttt tcaaaaaggg gcccaaacac
     1681 atctttcaaa gcatcttgca tgtcatcgac agattcaggt tgataggcat tcagaatgga
     1741 ttcagctaac ttttcggcat caggatttct tttctttcta gccatcgtgt aatcacctct
     1801 tgatcttatt gtagaaaaag aaaaaccgcg aagcaaccac ctgcctagga ttaatggtta
     1861 cttacacggt ttatattaca ctctcatcat taaaaaagta tctttcgata ttactaaaca
     1921 atgaaattat ctatttgaaa tttaaatctg ataatatatt gagtgttcca atgagggctt
     1981 tgatcctatt atccatatct ttttcagttt taatattgat acacattata agaaaaagaa
     2041 acttttggtt aatttatttc atcccagtgc aaaatataaa aaagtaaaat agaccatagg
     2101 caatagatta acaattaata taatacaagc aaatattcta ttcattgtat ttctgctttc
     2161 aaaaagttct aatattgaaa gtataattcc acaaatgcct ataataagta tgggaataag
     2221 attagaaaat aacaccccga gccaatctgt gaaaattact atatttacta atatccctat
     2281 taacatacct atcatattta ttaaatcaat ttttttcatt agatatttct cctttattaa
     2341 atctgaagta cttatattaa aataattcta aactatttac ctcaaaaagt gcaataaatt
     2401 atttctgaac aataaaatga tagtcaaaac aaaaaaatat tgttaatcgt tcagagccat
     2461 ccgagagtgt aaaatatttt gtgtaaatga aaaaatccat acaaaaaagg aaggcgcttc
     2521 tgtagaataa agttaacgac aaccaattca cagaaaagag gacttcccta tgaatgattt
     2581 tactacagaa attgtgcaaa ctctagtcac taaaggcg
//
LOCUS       DARPZJ010000134         2592 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.141, whole genome shotgun sequence.
ACCESSION   DARPZJ010000134 DARPZJ010000000
VERSION     DARPZJ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.141"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            120..626
                     /locus_tag="SLE23_002846"
     CDS             120..626
                     /locus_tag="SLE23_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEI8469668.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            643..1542
                     /locus_tag="SLE23_002847"
     CDS             643..1542
                     /locus_tag="SLE23_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HEI8469669.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKARR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            1629..2514
                     /locus_tag="SLE23_002848"
                     /pseudo
     CDS             1629..2514
                     /locus_tag="SLE23_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
BASE COUNT          941 a          480 c          508 g          663 t
ORIGIN      
        1 ttttgtcaca ccttcttttt tgtatataaa aatcccaagt aaatacataa aaaataaaaa
       61 aattgaaact tttagcgcac cttgtacgtc atattaagtg aggcagaaag gagtggagaa
      121 tgatttttac tggatataag aaaaaacggc agatcgaaaa ataccgtcac ctgctgaatg
      181 gactcatcga aactgattat caaaaaatgt tccgtatcac gatgaattac gtacatgata
      241 aagaagaggc cttagatgtg atgcaagata gttttcataa agccttgaac tattttgaaa
      301 aagaaaaaga gatcgagcat tttagtgcat ggttttatcg gatattgatc cgcacggcat
      361 tagatagttg gcgcagacaa aaaaggacgc ctgtggactt atttgaaatt caagatatcc
      421 cccaacagtt acctttagaa acttccgttg cagagctcca tatgatttta gataaaatag
      481 acagtccgga aaaagagatt ctgatcctct acttttttga aggatttcgt ttgaaagaaa
      541 ttgcaactat cttggatatg aatgaaaaca cagttaaaac gaaaatgtac cgctcattga
      601 atgctttacg tcaaatccta gaatgaagga gagaagagtg ccatgtattc ccaaaaagaa
      661 aatttaaaaa aactaaagaa aacttataaa gaacaagcaa ttcccaaagg gcttaaagag
      721 gagatccgcc agcgttttat tatcgaagag caatcattta taaaagcaag gcggagaaag
      781 agacgtctcc aagggttcgg agtatctttg gctatcgtaa tgattacaac aagtagcctt
      841 ctttttaata gtcaagttcg aagctttgca gaagatttac ccatcttagg atcagtcatt
      901 gaattgatct taggcgaacg ctttactgat cgatctgaaa aaatcgatat tcaggtaccg
      961 aagatcaata cacaaaatga gaaagaaaat aaaacaattc atggattaaa tcaaaaatac
     1021 tttcgcgaag gacaagcaga ttttgaaaaa gctgaaaaag aatatggaaa ttttgaaacg
     1081 gatcattacc aagttttggg agattatcag aaaatcgtag acgataaccg gtttctcgtg
     1141 attgaaaggc agatcaccca aacagcagca gatagccatg ttgaaaaaag atacgacaca
     1201 atcgacaaga aaaacagtgt ccagctctca cttccacttt tattcaaaga tgacacttat
     1261 ctatctgttt tgacaaaaga agtcaaacgg cagatggccg aacaagtcaa ggaagatcca
     1321 tctaagtact attggactga gcaagatatt caagaaggga cgatagaaaa accaacactt
     1381 gttacgccta cacgaagttt ttatttgaac aaagagcatc aattagtttt gactttttct
     1441 caatacgaaa ttgctcctgg ttatatgggt acaccagaat ttgtcattcc taagtccgtg
     1501 acaaaaacga ttttggcatc ggaagattat ttggatcatt agacgagaag tagttgcgac
     1561 tagcagtttc aattttcaag taagtacaag taaataataa gaagagaaaa agagaaagaa
     1621 gagatatagt gaaaagaaat tatttagtca tcagtattat tgctttatcc gtgcttttgt
     1681 ttttcgaaat tacttcggtg gcctccttga tcaccgaagt aaaaggacaa acacactctt
     1741 cggagcattc gtcacaatct ttcaaacaat cagaacaatc aaccattaaa agccaatcaa
     1801 ctgaaacagc taacgtcaaa gaagccattc aagaatcagc ggaaaaggta caaagtcaat
     1861 catcacaatc aacacaagac agtacagaag caatccaaga cccgactgtc aaaagcgtcg
     1921 caatcagctt tgatgatgga ccaggagcga ccacaacgcc gcagcttctg cgaatcttaa
     1981 aagaaaaaaa cgtgcatgtc acttttttcg tcttaggaga aaatacggcg cagcatcctg
     2041 aaatcgtgaa gcagacagct gaagcagggc acgagattgg caatcacaca tacgatcatc
     2101 agaatctggc cactctttct gcccagtcga tgacggagga agtgacgaaa gcagacactg
     2161 agatcaaaaa aagtcactgg caaaaccccc gcttttgttc gtccgcccta tggttctgtc
     2221 acgaatgtag gagcaacgat catccagcga ccgatcatcg aatggtctgt tgattcagaa
     2281 gattggaaga caaggaatcc tgatttgatt ttgcagaaga tccaagcaac agtatacgat
     2341 gggtcaatta ttttattcca tgatatctat cctgaaacga ttcgtgccgt tcctcaagtg
     2401 atcgattatc tgaaagagca aggctatcgc atcacgacag ttagcgattt attagggcat
     2461 ccaacggctg tcgagaacta ttatggcaga aacgatcatc ggccagttca gtaagtgaga
     2521 caagtatctt taataaataa cacattttaa taagtagttg aacacataac taccttactt
     2581 gcaaaggctt aa
//
LOCUS       DARPZJ010000135         2581 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.142, whole genome shotgun sequence.
ACCESSION   DARPZJ010000135 DARPZJ010000000
VERSION     DARPZJ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.142"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            282..614
                     /locus_tag="SLE23_002849"
     CDS             282..614
                     /locus_tag="SLE23_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEI8469670.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            1205..1534
                     /locus_tag="SLE23_002850"
     CDS             1205..1534
                     /locus_tag="SLE23_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469671.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            1521..1862
                     /locus_tag="SLE23_002851"
     CDS             1521..1862
                     /locus_tag="SLE23_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HEI8469672.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            1976..2215
                     /locus_tag="SLE23_002852"
     CDS             1976..2215
                     /locus_tag="SLE23_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469673.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPTRPVIKRKKKITQD"
     gene            2282..2521
                     /locus_tag="SLE23_002853"
     CDS             2282..2521
                     /locus_tag="SLE23_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469674.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
BASE COUNT          956 a          325 c          557 g          743 t
ORIGIN      
        1 aacggattta gtataacaga tattcaaaag tgataccact ttttttggct gtgttaaggt
       61 taaaaatacg tgatattacg atgaatctat gcctaagcat aatgttataa aaatgtccgt
      121 ggggctcttt gccgtatgac gaacgctgaa attagaggga acgcatgttt gaatgcgttc
      181 cctctttttt gtttgtcatg aacgaaaatc aattctctat ttttgaaaaa taacaagaaa
      241 aacttgttaa aaatatttaa agtaagtggg tggattattt tatgtcatat acaggaattt
      301 tgagtctcga agatatttgt cactacggta aacggtgtac cgctacagaa aagatcacga
      361 agaaactatc aactggtcaa agtaaaaccg ttgtgcagtg taagaaatat ataatccaga
      421 aagacaaagt ctcagaagaa atgatttatt acattgggaa acaaaaacaa ataattttaa
      481 aagatcctat ccctttaaaa gagctatatc caacaatcaa acatgtttat gaccaaaacg
      541 gtgtactgat tggtcgaaga aaaaatggag tcttgcgttg taccgcaaaa gggatggggc
      601 gtttaatcag ctgaattgat cattctcata acttgtattt tatcgttttt cgcttgcttg
      661 aaaatattgt cgagacttct aaaggaactt agaatcacta gaaaaataag gagtagactt
      721 gatctatcaa caattccctt cggggagtga cggggtaggt ttttacgatt ggtaacgtaa
      781 aaaattggtc aatcgagtaa atgcccttgt ttggatagtg gtgaaatgaa tttgtgtaaa
      841 taatatgcac agagtaaaca agagggaatt tagaagttag acaagttaga atagcgccta
      901 gattaatcat gagcagctac taagggatct aggctttgac gcaaactcat ggaataagga
      961 gtaggtcttc tcgtaatggg gaggacgcac aagaaattgt gtcgtgtgct gcagtacatg
     1021 tagatacttg cgaggacgtt gatcattgga tcaatcgagc atttaccgct gtctactagg
     1081 gtttctcgtt tcggacgcca taaacgagtc gatttatttt atatattttt gagtgaacga
     1141 aaaacgataa agatattcgt tatgaagtaa aactaattta gtagatagca aaggtggtag
     1201 aggaatgatt caaaaatttg cgaaaatgag taaaactgca tggattgaaa agcttgaaaa
     1261 tgacttgagt gtcatgcgat tagctccaaa gaaattcaaa cgagagattg cagaaaaaga
     1321 agcaattttg tcggtattga atgcggtaga cgataaatgt ccagtaaaaa ttagtttttc
     1381 agatatagca acaattatcg aaggtattta ttatggtgaa gttgatgaag agatatcttc
     1441 tacaaaagat ttattagatt ttttggataa aaacaaagat acctttatag tactaactga
     1501 ttatgaggag gttacaacaa atgaaaaatt atgatccgaa tatacgattg ggcacacata
     1561 cgattaaggt ttctttccaa cgttgggatt acaaaggatt tgtgacgttt agaagaggcg
     1621 gaaattgtaa aggattagat gttttagcat tagacgagga tgatttatac gatcaaacat
     1681 tgactgataa tccaattgga ttcggcttgc tacctgaaga tgatgaaggt aatgaatggt
     1741 ttaaaatgac gcttacggat gataatggag acgaattatc tgttgaagat acttggtcat
     1801 atttgagtga ttatattgtc agcgttgaaa tcattgaatt tgtagcggat aaagaagaat
     1861 aaaaactgga ggaataaatt ttacagataa aggcttagaa ggagtcacga cgaataataa
     1921 aaaggtagta ttaccttagg cattgagtaa ggaatttatt taggaggaaa attagatggc
     1981 gcgaccagtt ttagaggcga tggatatgga tactttgaca aaaggaaggt atgtacagct
     2041 gttagctcgt ggttattcac ctaaagatgt attcaaatcc ctgtctaaag gaacagatat
     2101 ggaaaaagaa agattacgaa aagaattcga ttattggaga acccataatg gaatcaagga
     2161 tttgaaacca acacggccag taattaaacg aaagaaaaag ataacccaag actgaagtgt
     2221 agagcgtatg tgatcatagg cttttttatt tttgcaaaaa acaagaaagg taggaaaact
     2281 catgaattat gaagaaatcg aaaacagaaa aaaagtgtcg aaagaaatgg aagaaaagtt
     2341 gctaaaaatg atgaaacaaa aacaccttaa aagattatct gtcatgcaat atatcaatga
     2401 tatgaagata acaggaaaag agaaagcttg tttgttaggt tcaatgaaaa actttgaaca
     2461 gttgaggcga acttatgtaa aaacaggttc caattgccaa ctattattag aagtttcttg
     2521 acgattatga tatgaaaatg atcaattatg atgtggcatt gttattgaat aaaaagaata
     2581 g
//
LOCUS       DARPZJ010000136         2542 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.144, whole genome shotgun sequence.
ACCESSION   DARPZJ010000136 DARPZJ010000000
VERSION     DARPZJ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.144"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(452..751)
                     /locus_tag="SLE23_002854"
     CDS             complement(452..751)
                     /locus_tag="SLE23_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEI8469675.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            1102..1734
                     /locus_tag="SLE23_002855"
     CDS             1102..1734
                     /locus_tag="SLE23_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEI8469676.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            1857..2495
                     /locus_tag="SLE23_002856"
     CDS             1857..2495
                     /locus_tag="SLE23_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEI8469677.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT          851 a          406 c          343 g          942 t
ORIGIN      
        1 atcatctctc aaaaatcctt tcttcaattc ctcccccact catttccaat cttttaacta
       61 aaaaattgat agttatttta caaatattta taaaaaataa atatgccaaa aaactgtttt
      121 tacaaggttt ttcctaatgt aaattatttt ttcgcatata ttcattttat tttacttatt
      181 gctttcattt tttcaatcta tatttccaat ttttaactta caaaaatgca acattaataa
      241 ataacgatag tttcataaaa tacactttta attaacatta ttagtttata ctagctgttt
      301 ttgtgttaat taaaggataa aatacaatat aaagaaacat ctgtttcttt atttagaata
      361 aaaaaataca gactctgttc aaataaatga acctagcctg cattatgaga ttgactatac
      421 tttttaattc attgagatga ataactcgtt tttataaatg cccaaaagta atcggtgccg
      481 aagccattcc tcgacctaat tctttttcaa attttcctat tgttgatatc tccatataaa
      541 acggtgatac tggtttagac aattctcccc tgattgctaa cggacgtaaa ctacgttcca
      601 aattatttat gactttagga taatactgac ctttttctaa gcctgtcttt gcgtctatca
      661 aaagtatacg ttccttttct ttgatctctg gatttaaaac gagatcatat aattttagta
      721 ccatgttttc tatttcttca cttttagaca tcacgatttc ctcccaaaaa tatatttctt
      781 cccactacat tctataaaca aagtatacgc tacatctaga tttttttaaa tcattactgg
      841 attgttaaaa cctttcaata cactgttatg gcaacgattt ttattttaaa aacattctaa
      901 attaaatcag taaaaatttt tattctaaga tttttattag aattacgcct aatttgtgtc
      961 tctcagggca attctaagaa cgtttcaaga gatagcgaca ctatcgttat cgaaaaaggc
     1021 gaaaacctat ctcattttct gctaatgtaa gttggtttag cttttgttaa tatgacttta
     1081 tgaaaatgga ggtaattaaa tatgattttt cctaaagtta atgaagcaag cttgaataaa
     1141 ggatcctttt ttcatatcta tgaaaacgaa gattttgaac tgtataatat cctttcacaa
     1201 aaagaggtca tcgaaaacca aataatctgc catccaatta tttacaaatc tattttcaag
     1261 tatgcatttt ttgcttccaa tgattttcaa agaatggaga ttaccgactg tatattcgaa
     1321 aactgtgatt tttcaggctg tatattgaca aaaagcatgt tgcatcgcgt gaaatttgtc
     1381 aattgtaaat taacaggtac taaattgatg gaaagttata ttgggaacac gttattcgag
     1441 aattgtaaaa tggactatgt aaatttatct ggttcaaaca taaaagaaag tacctttgag
     1501 cactctgtct tatcaagcgc agattttgta gactgttccc tcactaaaat aatgttttct
     1561 actaatgatt tagaaaatgc tagctttttt gatactgatt taaaaaatat cgatttaagt
     1621 agcaactcct ttgaaatgat tgaagtacgc tcggaacatc taaaaaattg tacgcttaat
     1681 cagttgcaag cacttggttt tgctagaaaa tttttacaaa taaaagtagt ataatcaaaa
     1741 tgaatatata agataaattt ttagcaatac aaatatccat aaaaaaacat tgcctatttt
     1801 aactcttcat gtatactgac tctatcttca aaaactgaat agtaggagtt attatcatga
     1861 ataacatttt aggaaaaaaa atagaactta aaaaagggat attgggcact attgtcgttg
     1921 tactcggttt gttagggttg ctatttgcgc catccattat tagcattttt tctttaacta
     1981 tcactggatt tatagcattt acacttgttt ttggtaaaaa agatacgaaa aaaatgttct
     2041 cgaaacctgt cgctcctgtc aaaaatatag ccaaatattt ttttatcaat gtagtaatca
     2101 gtgccgcagt ctcggtattt ttgcaacaaa ttttgaaatg gggtttaaca ggcaatccaa
     2161 taaatgaggc tttcagcccg ttattattta ttattttgcc tatcatgata cttggagaag
     2221 aattgttctc agtgtatttt ctcgctattt tttctagtaa gttcagcatt cctgtcgcta
     2281 gtttcttgtc agcaatcatc tttggattta tccattacag tacttatgat aatggaaata
     2341 ttttacacac tgtagcacac atccttttga tacaaggggt ggcaagattg ttattcaacc
     2401 aagctgccat taaaagcaac tcgatcatta caagttgggc agttcatgtg atatttgatt
     2461 tcacagctat attgctagtc gttttattct cctaaatttt tatagaaata atacatgctc
     2521 tattgctaag aaagcatact tt
//
LOCUS       DARPZJ010000137         2399 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.145, whole genome shotgun sequence.
ACCESSION   DARPZJ010000137 DARPZJ010000000
VERSION     DARPZJ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.145"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            206..2068
                     /locus_tag="SLE23_002857"
     CDS             206..2068
                     /locus_tag="SLE23_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8469678.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2399
                     /locus_tag="SLE23_002858"
     CDS             2068..>2399
                     /locus_tag="SLE23_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8469679.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          715 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataatta
//
LOCUS       DARPZJ010000138         2281 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.146, whole genome shotgun sequence.
ACCESSION   DARPZJ010000138 DARPZJ010000000
VERSION     DARPZJ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.146"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..93)
                     /locus_tag="SLE23_002859"
     CDS             complement(<1..93)
                     /locus_tag="SLE23_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEI8469680.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSI"
     gene            1242..2261
                     /locus_tag="SLE23_002860"
     CDS             1242..2261
                     /locus_tag="SLE23_002860"
                     /inference="COORDINATES: protein motif:HMM:NF019371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEI8469681.1"
                     /translation="MKTSNRKYKVKTVNHRIPPKKALCVINNSKVINQELKPYLSEQE
                     MIKKISKDIFLTNSDTILLEKFLKKNSYFRFSIYVKLMKNIDKVTILDVIETYKLDSF
                     IRNQLHYFVNQIEIFWKKSLSDNMCVSYEETSIFPKNQCYLDKNIYSDLKWAEDIIGH
                     FNSFFYSNQSPTFKHHHIKKNHCLPIWALFEEITFGSLTTFINQLNTEYYNNWVMSCY
                     DNPKYKKAIRSWANVIRAYRNKIAHHSRIYAFKVTDAPTIIKNDSKSYFPENNLKETQ
                     KLYLYGGLYVIKHLLIYEDSMTQTLWNKFLIDLEKKIDKIPSLEKSNYGFPENWRNKL
                     KIMIV"
BASE COUNT          867 a          352 c          365 g          697 t
ORIGIN      
        1 tatagagaag aataaattca tttctactga cgtaaatttg cgtaaaggaa tcgtatttaa
       61 ttcatggtgg tatttcacaa tttcatttgc cataaaatcc tccttcaaga ttaactactt
      121 aacaaaatta taaagagctt tctaataggg gtcaagcccc taattaaaga cccctaaaaa
      181 cagacaaaaa gacccccaaa aacagacaaa aagaccccta aaaacagaca aaaagacccc
      241 taaaaacaga caaaaagacc cccaaaagat tctgcacacc ttgggagagt aagcatacag
      301 ccgacggtaa agaggtttaa aaagaggttt aaaaagagat tataaaagag gagaggggca
      361 aaatttcccg cctaaaaatt ttctgctttt ttagccaaac aggttcgcga attttactaa
      421 actgggaaac ttgctccctc tggtcgctaa aaaggtgtga gggaaaaaca ccctcacatt
      481 gtacctgcgc agtcgcctaa aggctccttt gctaaaaacg ttgtttaaag agattttttt
      541 agaggctctg cgcgctcgtt taagccgttt taagacagtt tagtatggat aacccttatc
      601 ttgttcttaa agcaccttac aggcggtcag ggcaagccct aacaaccctt aaagagcata
      661 aaaccatcct aaaattcgat ttaatctgtc ttatctatgt tcttgtatat tttatatacc
      721 ttgggtagta aaacgtctga aaacgcaaat aagagcgtat gaaacaaaac aataagcaac
      781 cgattcagca gaattccgga ggagccattt tcgtacgtta gcaaaaaagt gctgttgcta
      841 aaagctgctt gcggtgcgga gcgaacaagg tctcctagag cgagacgtgt acaaacaagc
      901 ttacaaattc gtgaaaggca ccggttttgc gccatttcca agcaaaaaaa ggtctatcga
      961 gcaagctcga tagaccgatc gcatttagcc ccccgcattc taacaggggg ggaataatgt
     1021 gaaaaattat ggtagtaatg cttgatatat aggcatttct tttggttgca cacttaaaaa
     1081 aaatcacgat tttgacaact aaatttttaa ataaaaaagc tttacagttt aattcaaatg
     1141 tgttttaata tatctatcag tacttgccac gcctctgatt taatatcatg cgcattatgg
     1201 tagggctttt tttttatatt tttttaagaa agaagattct tatgaagaca tcaaatagaa
     1261 aatataaagt taaaacagtt aatcatagaa ttccacctaa aaaggcatta tgtgtaatta
     1321 ataattccaa agtaattaat caagagttaa aaccatattt atccgagcaa gaaatgataa
     1381 aaaaaataag taaagatatt tttttaacaa attccgatac aattttatta gaaaagtttt
     1441 taaagaaaaa tagttatttt cgatttagta tttatgttaa attaatgaaa aatatagata
     1501 aagttactat tctagatgtt attgaaacgt acaaattaga ttcattcatt cgtaatcaat
     1561 tgcattattt tgtgaatcaa atagaaattt tttggaaaaa atctctttca gataatatgt
     1621 gcgtttctta tgaagaaact agcatatttc cgaagaatca gtgttatttg gataaaaata
     1681 tttattcaga tttgaaatgg gctgaagata taattggtca ttttaatagt tttttttatt
     1741 caaatcaaag tcccactttt aaacatcatc atataaaaaa aaatcattgt ttaccaatat
     1801 gggctttatt tgaagaaata acatttggta gtttaacaac atttattaat caacttaata
     1861 cagagtatta taataattgg gtcatgagct gttatgataa tcctaaatac aaaaaagcta
     1921 tacgaagttg ggcaaacgta attagagctt atagaaataa gatagctcat cattcaagaa
     1981 tatatgcatt taaagttact gacgctccaa caatcataaa aaatgattcc aaaagttatt
     2041 ttcctgaaaa taacttaaaa gaaacccaaa agttatattt gtatggagga ttatacgtta
     2101 taaaacatct gttaatatat gaagatagca tgacacaaac tttatggaat aaatttctaa
     2161 tagatttaga aaaaaagatc gataaaatcc cttccttaga aaaatccaat tatggttttc
     2221 cggaaaattg gagaaacaag ttaaaaataa tgattgttta attgttattt aaattgttag
     2281 t
//
LOCUS       DARPZJ010000139         2164 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.148, whole genome shotgun sequence.
ACCESSION   DARPZJ010000139 DARPZJ010000000
VERSION     DARPZJ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.148"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..111
                     /locus_tag="SLE23_002861"
     CDS             <1..111
                     /locus_tag="SLE23_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8469682.1"
                     /translation="YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            325..1020
                     /gene="vanR"
                     /locus_tag="SLE23_002862"
     CDS             325..1020
                     /gene="vanR"
                     /locus_tag="SLE23_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEI8469683.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            998..2152
                     /locus_tag="SLE23_002863"
     CDS             998..2152
                     /locus_tag="SLE23_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEI8469684.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          730 a          400 c          461 g          573 t
ORIGIN      
        1 tatgcggtaa agctatataa agaaggaaat atgactgtaa atcaaatttg tgaaattact
       61 aatgtatcta gggcttcatt atacaggaaa ttatcagaag tgaataatta gccattctgt
      121 attccgctaa tgggcaatat ttttaaagaa gaaaaggaaa ctataaaata ttaacagcct
      181 cctagcgatg ccgaaaagcc ctttgataaa aaaagaatca tcatcttaag aaattcttag
      241 tcatttatta tgtaaatgct tataaattcg gccctataat ctgataaatt attaagggca
      301 aacttatgtg aaagggtgat aactatgagc gataaaatac ttattgtgga tgatgaacat
      361 gaaattgccg atttggttga attatactta aaaaacgaga attatacggt tttcaaatac
      421 tataccgcca aagaagcatt ggaatgtata gacaagtctg agattgacct tgccatattg
      481 gacatcatgc ttcccggcac aagcggcctt actatctgtc aaaaaataag ggacaagcac
      541 acctatccga ttatcatgct gaccgggaaa gatacagagg tagataaaat tacagggtta
      601 acaatcggcg cggatgatta tataacgaag ccctttcgcc cactggagtt aattgctcgg
      661 gtaaaggccc agttgcgccg atacaaaaaa ttcagtggag taaaggagca gaacgaaaat
      721 gttatcgtcc actccggcct tgtcattaat gttaacaccc atgagtgtta tctgaacgag
      781 aagcagttat cccttactcc caccgagttt tcaatactgc gaatcctctg tgaaaacaag
      841 gggaatgtgg ttagctccga gctgctattt catgagatat ggggcgacga atatttcagc
      901 aagagcaaca acaccatcac cgtgcatatc cggcatttgc gcgaaaaaat gaacgacacc
      961 attgataatc cgaaatatat aaaaacggta tggggggttg gttataaaat tgaaaaataa
     1021 aaaaaacgac tattccaaac tagaacgaaa actttacatg tatatcgttg caattgttgt
     1081 ggtagcaatt gtattcgtgt tgtatattcg ttcaatgatc cgagggaaac ttggggattg
     1141 gatcttaagt attttggaaa acaaatatga cttaaatcac ctggacgcga tgaaattata
     1201 tcaatattcc atacggaaca atatagatat ctttatttat gtggcgattg tcattagtat
     1261 tcttattcta tgtcgcgtca tgctttcaaa attcgcaaaa tactttgacg agataaatac
     1321 cggcattgat gtacttattc agaacgaaga taaacaaatt gagctttctg cggaaatgga
     1381 tgttatggaa caaaagctca acacattaaa acggactctg gaaaagcgag agcaggatgc
     1441 aaagctggcc gaacaaagaa aaaatgacgt tgttatgtac ttggcgcacg atattaaaac
     1501 gccccttaca tccattatcg gttatttgag cctgcttgac gaggctccag acatgccggt
     1561 agatcaaaag gcaaagtatg tgcatatcac gttggacaaa gcgtatcgac tcgaacagct
     1621 aatcgacgag ttttttgaga ttacacggta taacctacaa acgataacgc taacaaaaac
     1681 gcacatagac ctatactata tgctggtgca gatgaccgat gaattttatc ctcagctttc
     1741 cgcacatgga aaacaggcgg ttattcacgc ccccgaggat ctgaccgtgt ccggcgaccc
     1801 tgataaactc gcgagagtct ttaacaacat tttgaaaaac gccgctgcat acagtgagga
     1861 taacagcatc attgacatta ccgcgggcct ctccggggat gtggtgtcaa tcgaattcaa
     1921 gaacactgga agcatcccaa aagataagct agctgccata tttgaaaagt tctataggct
     1981 ggacaatgct cgttcttccg atacgggtgg cgcgggactt ggattggcga ttgcaaaaga
     2041 aattattgtt cagcatggag ggcagattta cgcggaaagc aatgataact atacgacgtt
     2101 tagggtagag cttccagcga tgccagactt ggttgataaa aggaggtcct aagagatgta
     2161 tata
//
LOCUS       DARPZJ010000140         2156 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.149, whole genome shotgun sequence.
ACCESSION   DARPZJ010000140 DARPZJ010000000
VERSION     DARPZJ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.149"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            221..1591
                     /locus_tag="SLE23_002864"
     CDS             221..1591
                     /locus_tag="SLE23_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HEI8469685.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1612..1896
                     /locus_tag="SLE23_002865"
     CDS             1612..1896
                     /locus_tag="SLE23_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469686.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          741 a          315 c          455 g          645 t
ORIGIN      
        1 atatgtagtc ctcatttctt gggagttttg agactactat atgcgttttt tgttgattta
       61 ccaacatgtt tagacatttt cctctaggaa aaaattaact agcaccacgc gtattgttta
      121 tattaaatta gatgaccgtg ataatgcaca gcaaattttt gaaagtatca attctaccgg
      181 tgaaagattg actgcctcgg atttgattcg aaacttcatc atgatggata aatctaatga
      241 agagcagact acgctttata ctaaatattg gcgtaggttg gaagaagtct ttgataattc
      301 taaaggaatg gaagactttt tcagatacta ccttgctgca ataactgggg agtattcagc
      361 aaagcatatt ctttatcaag cattcaaaga ctattggcat aaagagcgcg atgtatcaag
      421 tgatgccgaa ttgctccaaa aattagtgcg atatgctggt tattttgcga gactttacta
      481 taacaaacct gaaggaaaat actcagaagt attgagcgat ttccaaagta tggaaagtat
      541 gatgcctgca ccttttgttt tgggattatc tgaatggtac tatcatgacc aatttatcac
      601 tgaagaccaa tatattgatg cgattaaggt agtgaatgat tatcagctta ggagatattt
      661 taatggggat gatacaagca gagtgtcaaa agcatttcct tcatatttga aaagtgttag
      721 gaagtacgct aaagctaatg gatatgaaaa tatcgttgat attgtaattt atgttcttgt
      781 tactagaaat caatcaaata atatggcact tccatctgac aaggcattga aatctaatct
      841 attgaatgcc aatgcttatg cgatgagatt ggcccgttgg ttacttgaaa aaatagagaa
      901 tcgagaaaat tcagcaacac ttgatatgag taacttgtcc attgaacaca tcatgccaca
      961 gactagtact tcatattggg aagagaaggc tggtacatcg ggggaagaat acacaggatt
     1021 agtaaatacc attggtaatt taacactcgt tacaaatcct gataattcgg ccgcgggaaa
     1081 taaagacttt gagaccaaaa agaaaatctt tgaagatacc cttcatattc gtatgaataa
     1141 agatttgtac gaattgactg agtggacatc atcggatatt tctgccagaa gtgaagctct
     1201 aatcaatgaa ctgattacta tgtatcccta tttgagatcg tcgggcgact atgaacacga
     1261 tgggaatagg gaaattttct tagaggcgca aggaataaaa gcaactgggt atttgaacga
     1321 agacgagacc gtgattatac attcaggttc agaaatttat tctaagatta aagatattgc
     1381 atctgattcg ctagatgaaa ctcgccaaga gctgttggat aatggaatca ttgaagaaac
     1441 aattggggga ctacaatttg ttcaagatta cactgcctca tctgtttcga atgcagcagc
     1501 tctgctatta gggggtagcc ggaatggttg ggactactgg aaatatgata acggaataag
     1561 tattaatgat tcgctaagaa ataagaaata gagcatagag gtggtgttag gttggataag
     1621 aacaaactaa gatatgcaat tcttaaattg cgtgatgaaa aaaagaatcc ttttattgag
     1681 cttaaagggc aagttccaga agaagatatt ttagaacaaa ctaaatttct ttcgcgcaat
     1741 ggcttactag aatccatggt ttgggcggat aacactgttc atatctgggg gagtgtttct
     1801 ctggaagggg aaaaatattt agttgaaaac tcaggtcttg ctaaggcgta tgcattggca
     1861 aaagaagtta aaaattggat tccattttgg ggctaagata agtttttaaa cggagaaggt
     1921 agcaaatcat aattggtttg ttgccttttt tgattgccca aaaagaaaaa tgacaaagta
     1981 tagagataaa tgacatagta cacgggaaaa atgacattgt atcaccgaca acgtctaaat
     2041 agatgttgat atatatacgt tccgtacaaa taattataaa aatttaaatg atttgagtag
     2101 aagtatcagt gaatatctca aggggaatag ctatctcaag attcgatttt cacata
//
LOCUS       DARPZJ010000141         1981 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.150, whole genome shotgun sequence.
ACCESSION   DARPZJ010000141 DARPZJ010000000
VERSION     DARPZJ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.150"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..196)
                     /locus_tag="SLE23_002866"
     rRNA            complement(<1..196)
                     /locus_tag="SLE23_002866"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(869..1225)
                     /locus_tag="SLE23_002867"
     CDS             complement(869..1225)
                     /locus_tag="SLE23_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HEI8469687.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(1239..1649)
                     /gene="spx"
                     /locus_tag="SLE23_002868"
     CDS             complement(1239..1649)
                     /gene="spx"
                     /locus_tag="SLE23_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEI8469688.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          591 a          379 c          299 g          712 t
ORIGIN      
        1 gattgttata cggtattagc acctgtttcc aagtgttatc cccttctgat gggcaggtta
       61 cccacgtgtt actcacccgt tcgccactcc tctttttccg gtggagcaag ctccggtgga
      121 aaaagaagcg ttcgacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga
      181 tcaaactctc ataaaaagtt cgaacaatct tgcgattgtt aagctcaatt tgtttgctag
      241 catattgctt gcttgttaaa aaatgtttgt tgtcttgaat tgaatcaaga cgccctacac
      301 atttggtttg tcttactttg ttcagttttc aaaggtctac ttcatcagga gtgttccccg
      361 attcgttttt ggctgccgta gcaactttta tatcatatca gagagacaag taattgtcaa
      421 ctctttttta aaagtttttt tgatttcgtt tttcgaaatc ttacagcaac tcatttatca
      481 taacttatca tttgttattt gtcaaggact tttttgaagt ttttttcgat agaatcaagc
      541 ttcacaagtg gttctttttt aacaactcag ttatcttatc atgtcatttc taacatgtca
      601 acaactattt tatatgtttt ttaaaatact attttattgc tttgctactt aaaacaacag
      661 aaatgaatat atcatgtaaa tttacacatg tcaatatatt tttaactcta tatccccacc
      721 tagatttgaa ttttgaccac ataaattgag catgtctcta tagtagaaaa ataaagtcaa
      781 aaaaagaaca cataacacgc ttgatgctaa gtgttcgact gttacaactg tatgaaatgc
      841 tcagtgactt gattaaaaca gttaaagtct atttatttaa gataagctgt tccatcaact
      901 gctcattgta tccaataaat agaacttcat cgataataat caaaggacgt ctgaggagat
      961 tggtatgttg tgtgcataaa aaaatcagtt gtttttttcc tacacaggaa aggtcaatcg
     1021 caatgttgtg aaaagcctca gaccaagtcg caaatagctg ttctgcttgc acttcttcaa
     1081 aactgcataa ttcttctgct tcttctgtac ttagatcgcg ttcttctaag tcaacaaatt
     1141 gataaggcaa ttgatggtgt tctaaccatt gtttcgcctt cagacttgtt acacagtgcg
     1201 ctgatccata gactttcact tccacgaagg ctccctccct atgaatttaa gatgttattg
     1261 ttttgtaaat agatcagatt tctggcaaca catcgaattt cacgagggac aaatgaccgg
     1321 atctcatctt cattaaatcc gattagtatt cttttttcat caatcaaaat aggtcgtctc
     1381 aataatgaag gatattcttt gaataagacg atcatttgct ttaaagttaa ttcgttaaaa
     1441 tctatgccca gcttttcgta aattttcgac cgagtggaaa taatatcttg aactcctcct
     1501 tcagtcgctg ccaagatctt tttgatctca ctttctgtta acggttcggc aaaaatattc
     1561 ttctcttcaa attcaagttg attcgcttgc aaccatgctc ttgcttttct acaggaagta
     1621 cagctaggcg aagtatatac ttttatcatt ttctcactcc tttttaatta taatccaatt
     1681 ctacagtaat ttcttttaaa ataccaatta ttagctaata aaatataaaa aaaatcaaaa
     1741 taactgatta tttacgtttg aataatgaga atttttctat atattctcta ttttgataat
     1801 agtattctca ttttcaaaat aaataaggga ggtgtgacaa aattcttgtc acacctccct
     1861 tttccgaata aactgtgttc cagaaatagc ttcttcgaaa ataagctgaa atttcacaaa
     1921 aatttgagaa gcaattttcg tacattcctt cttctttctt gaaactgacc acttctgtca
     1981 c
//
LOCUS       DARPZJ010000142         1980 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.151, whole genome shotgun sequence.
ACCESSION   DARPZJ010000142 DARPZJ010000000
VERSION     DARPZJ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.151"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(325..529)
                     /locus_tag="SLE23_002869"
                     /pseudo
     CDS             complement(325..529)
                     /locus_tag="SLE23_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(729..1745)
                     /locus_tag="SLE23_002870"
     CDS             complement(729..1745)
                     /locus_tag="SLE23_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEI8469689.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          558 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaaa attttcctaa ttgtgacatg gctgtcacaa
      541 ttccaaatgc tctccgaggg tattcgctgt cacaagtgac aacgaaaaaa ggagccgaaa
      601 gcgtgtcacg ctctcaactc cttttacgct ttattttgct tcatgcaaaa tattcgctta
      661 tcgtgaattt acgtcactaa acattgacgc aaatccactc tcactcatct gacttttctt
      721 attcggtatc acttctctgt cacatccaac cccaaaagcc acgtatccaa ttcttttttt
      781 aattcgtctg cagattcctt aaacgtctct cgtaaatgat tcgttaactc atcattttga
      841 ctttcttgct tcagcaaatt ccgatattta tattttgtat gtctagcaat tatcgaccaa
      901 ttagaaggct cagctatcaa accatcaata actattttat caataggttt tatatcaatc
      961 ggcaaaaaat gcgggcttgc aaaactatct aagctttcct gaaccatcgc atgccaatcc
     1021 gttgctttgc cacgtcttag ctgcatttct aaccgccacc acgtatcgat ttcttttggc
     1081 acgattactt tttttcgttc ctgctctagc tttttgttgt acagtcgcac ttggcgctca
     1141 ctggcacgac tgccccagta cgctgtttct agcttgccag aacggccgta gattggctta
     1201 aaagaaatcg ggtctacaat acgatactga gtaataaagt catccggcac atctacaata
     1261 tcgcaggcaa tatccgcccg ggaaaaatgc ggatctaaaa ataggtcatg aatgaatcct
     1321 ttcatggaac tagctaaaaa ctggcctatc ttattcggat taaaatcaat acgacctttt
     1381 ccttcatgaa atttaagtat ttcgatatac gcaatatctt ctccatattg atcgaataat
     1441 tgccagccgt ttatcccaac tgatttcaaa tatccctgat tttcgttcaa acgcattaat
     1501 tgctcgaaat cgacaaaaac aactccattt ttcgtccaat aagctatggt atcattcagt
     1561 tttccgacaa ttgtaattcg atcaatcgac caatttaatt ttaggggggt ggtcgtacct
     1621 tgcacactta accgcctgtt agaaatacgg ttaagttttt cgagctgatt tatcgttgtt
     1681 cttttttctg cccctcgacc ttcaattttt gattgaattt cactcaactg attttcattt
     1741 gccattttcg tcctccaaac gaaaaaagag acttttggaa agaatttcca gagttcacgt
     1801 aaccctaaaa attcatatcc aaaaatctct agcttgaaga aacctaaaaa tattcgtata
     1861 atgaacctga gttacggagc taggtgaagt agtttccgta aatagtcgag agtgttagcg
     1921 cactgctcgg cttttatttt gctctttttt ctcgttttct ttgattatag cactcctcct
//
LOCUS       DARPZJ010000143         1947 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.152, whole genome shotgun sequence.
ACCESSION   DARPZJ010000143 DARPZJ010000000
VERSION     DARPZJ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.152"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            217..1206
                     /locus_tag="SLE23_002871"
     CDS             217..1206
                     /locus_tag="SLE23_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEI8469690.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1203..1622
                     /locus_tag="SLE23_002872"
     CDS             1203..1622
                     /locus_tag="SLE23_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469691.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1601..1939
                     /locus_tag="SLE23_002873"
     CDS             1601..1939
                     /locus_tag="SLE23_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469692.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
BASE COUNT          694 a          251 c          433 g          569 t
ORIGIN      
        1 aggcaactat ttctgcgaag aaatcggggc tatagtatgg gtctatccct tgtggctcta
       61 aggaagaaca aaaaaaaaga ttgctttttc ttccctagta ttttatagtt ttaattgact
      121 agaaaaaaac taaactagaa aggagagcaa tctatttttt gttatcggct tttcagcctt
      181 ttttgtatac aaaatttgta gattcagtat agcaagatga aaaagaaaaa gcaagatttg
      241 attaacggaa catttcgaga aaaaaagaaa aatttgaaaa aagtggtggc atttagtgat
      301 aatcgaattt ctcccaaaat gcgtgaattg atgacaggct gtggttcata tttagaattt
      361 attgcaacga ttgataagga gaaaaagaaa ttggtccaag ctcacttttg taaaaatcgt
      421 ttctgtccgt tatgtgcttg gcgtaaagct cgtaaggatt cgatgatgtt gtcgattatg
      481 atgcaagcta ttgcggaaga aaagcagtat caatttattt ttatgacgtt gacgacaccg
      541 aatgtaaaag cggaatgttt gaacgatgaa attgatttgt ttaatcatgc attgaaaaag
      601 atgtttatgc gcaaacgggt taagacttcg attaaaggct atgtgcgaaa attggaaatc
      661 acgtacaaca aaaaacggaa tgactataac ccgcattttc acttgatttt ggcagtaaat
      721 aaatcttatt tcacggataa agattattat atcaagcaat cggaatggtt agatttgtgg
      781 cgggaagtga ccggaaaaac gggaattaat ccggatggta ccgacgaaat tacccagttg
      841 gatattcgca aggtcaaagg gttccaacaa gaaaaagcag tacaggaagt tgcgaaatat
      901 tcggcaaaag attttgaact gaccgaaagt caggaagtgt ttgacacatt ctatcatgca
      961 atgaaaggtc gtcagttgat tacgtttaac ggtgtattca aagaatacaa gaaaaaatat
     1021 gagtcgggtg accttgatcg ttataagaaa aaagatgaga atgaatattt ttggtttttg
     1081 actgcttcgt ggatgaggaa agaatcgaaa tatgcggttg attatcgtga gatgagtgct
     1141 gatgaaagaa attatttttc aggaatgtat gtcgatgaaa aatctgttga gggggaaaat
     1201 gaatgactga ttcaacggat aaaatgacaa ttaaggcgct tgctgatgaa ctaggaataa
     1261 ccaaaaatac agtgagaaat tatctagtca aagccggata tgatcttgct cggtacaaga
     1321 aaaatggaat tatcttgcta gacaaagagt tgattggtgt tgctcggtca atttatcggt
     1381 caaaaggtgg tcaattgact ggtcatttac cggtcaatag cacgggcagt gattttcctt
     1441 tggaaaaaga gaatgagttt ttgcgtgatc aattagctga gaaggacaaa catatttctg
     1501 aattaacaga aatgattcgt gatcaacaaa aattgaccct gcttcagcaa caaaaaaacg
     1561 atcagttgtt actagaaaat caagaattaa aaaatcgaaa atggtggcaa ttctggaagt
     1621 gagatgtgac atggataaaa ttgatttgag agaagaaaca gtcaatagaa ttgaagtgat
     1681 gtatgaacgg ttagctgatt atttgaatct ttcggatgaa gataattata gtgagatgct
     1741 tgaacgaatg atggatgttc tcaactcggt tatcaatgct gatctagcaa aatcttcagt
     1801 tttgactaat gaatttgttc ataagcattt agcgcaaaca actgatgaag ctgaaaaaga
     1861 attttggttg aaattaatga gtcatattat gcagttaaac caaatttccg ttattaattc
     1921 caaagaaaag gggatgtagt ttatggg
//
LOCUS       DARPZJ010000144         1932 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.153, whole genome shotgun sequence.
ACCESSION   DARPZJ010000144 DARPZJ010000000
VERSION     DARPZJ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.153"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            7..1185
                     /locus_tag="SLE23_002874"
                     /pseudo
     CDS             7..1185
                     /locus_tag="SLE23_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          659 a          364 c          322 g          587 t
ORIGIN      
        1 ttccatatga acgattttac tacagaaatt ctaaagactc tagcgaacaa aggcgatttg
       61 aatgaattat tccgtgtcca tttggaaaaa gctgtcaata cgcttctcaa aacggagtta
      121 acggctttcc tcgattacga aaagtacgat cgcattggtt ttaacacggg gaattctcgt
      181 aacggctcct atgaccgtac ggtcaagacc gagtacgggg aacttcatct ccagattccg
      241 cgcgaccgca acggcgagtt caagcaacag actgttcctg cttatagacg gacgaatgat
      301 accttagagg agaccgtcat tcacctcttc cgaaaaggta ttaccatgtc ggaaatcgca
      361 gacttgattg agaaaatgta tgggcatcac tacacgcccc aaaccatgtc caacatgact
      421 aaagtgctga ctgaagaagt aaatgcattt aaagttagaa ctctaaatga taagtatgtc
      481 gctattttca tggatgctac ttatattcct ttaaaacggc aaaccgtctc caaagaagca
      541 atctatattg ccattggtat acgagaagac ggcactaaag aagtactaag ttatgcgatt
      601 gctccgactg aatcgaccta cgtttggaat gagttgttac aggacattta ctccagaggg
      661 gttcatgatg tcttactgtt tattaccgat ggcttaaaag gcatgaaaga tacgattcac
      721 cagatttatc ctaaagctaa ataccaacat tgctgtgttc acgtttcccg taatattgct
      781 cataaagtac gtgtcaaaga tcgaaaagaa atctgtgatg attttaaggc tgtttatcaa
      841 gctagctcaa aggaagaggc aaataccttt ttagggagta tgattgagaa gtagcaaaaa
      901 acttatccta aagtgacgca gtcactgata aaaaatcaag atttattgac tttttatgag
      961 tttccgcctg gtatccgccg aagcatttac tcaactaatt taatcgaatc tttcaagaaa
     1021 caaatcaaga aatacagccg cagaaaagag cagtttcaaa atgaagaatc actagagcgt
     1081 ttcctagtat ccatctttga tacatacaat caaaaattct taaatagaag ccataaaggc
     1141 ttccaacaag tgacggatac attagcttca atgtttactg agtaacccat tattttgcag
     1201 aaggacgagt tatttacaca aaattattga cgctccctcc aaattacttc atcaaaacat
     1261 tgatataatt tttattatat cagtatttat tcttgataca taaatgagaa aataaatact
     1321 ttaaatctat tgactacaag tagtcattaa gtcttcataa gatgtacaat atgacattaa
     1381 aaaaataaaa gcttacgacc atccgttaaa tctgacacta aataatggac tgctttcttt
     1441 tgtattagca ggttacgttg actatgaata ttcaccagat tatttggaga aacctcttca
     1501 acacgagaac aatgatatta attttagatt tgtctacgag tcaaaaagta aaacatggtt
     1561 agttgatcaa ttaagcacga taaacacaag cttccatgaa ttacctaaac ctgaaaatga
     1621 agttgagatg gtcattaaaa tcttctaaaa aagaagcgtt gaaggggaaa tattcctttc
     1681 aacgctcttt tttatatgct tagaaacata aataaattgt atactttctt tttagcccct
     1741 attacttttc acgaaaaata tctttttttc gacgctagcg tttctctact tctaatactg
     1801 tacacagttt ttgtattatt gaaaaattac tcattattta gcattaatcc acatcgtttt
     1861 atcaatcgac cttcatacta aactacttta aagtcatctt ccttctcgtt tttcattaat
     1921 ggaatggcaa ca
//
LOCUS       DARPZJ010000145         1828 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.154, whole genome shotgun sequence.
ACCESSION   DARPZJ010000145 DARPZJ010000000
VERSION     DARPZJ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.154"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            131..505
                     /locus_tag="SLE23_002875"
     CDS             131..505
                     /locus_tag="SLE23_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEI8469693.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="SLE23_002876"
     CDS             complement(619..1248)
                     /locus_tag="SLE23_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEI8469694.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="SLE23_002877"
     tRNA            complement(1382..1454)
                     /locus_tag="SLE23_002877"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="SLE23_002878"
     tRNA            1668..1741
                     /locus_tag="SLE23_002878"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
BASE COUNT          629 a          267 c          317 g          615 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttt
//
LOCUS       DARPZJ010000146         1729 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.155, whole genome shotgun sequence.
ACCESSION   DARPZJ010000146 DARPZJ010000000
VERSION     DARPZJ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.155"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            129..1298
                     /locus_tag="SLE23_002879"
     CDS             129..1298
                     /locus_tag="SLE23_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8469695.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
     gene            complement(1638..>1729)
                     /locus_tag="SLE23_002880"
     CDS             complement(1638..>1729)
                     /locus_tag="SLE23_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEI8469696.1"
                     /translation="GLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          613 a          282 c          284 g          550 t
ORIGIN      
        1 aatatcccat attttaaaat aaaagatagc gtaaaatatt ttgtgtaaat agaaatttag
       61 ggtagaaaaa aaagtccatt ctgtaaaatt aaagttacca cacagaaatt ttataggagg
      121 actttctcat gactaaattt actatagaaa ttatgcaaac actactcaat aaaggggatt
      181 tagatgaatt atttcaggat catttagagc gagcgattaa ttcacttcta caagcagagc
      241 taactgcttt tttagattac gaaaaatatg atcgaaatgg attcaattca ggaaattccc
      301 gtaacgggaa ttattcacgt acatttaaaa cagaatatgg cgagttgaat ttaactattc
      361 ctagagatcg gaatggcgaa ttttctcaac aaacactacc agcatataag cgaaccaatg
      421 attcattaga aacgaccatt atccaattat ttcaaaaagg cattactatg gctgaaatct
      481 ccaaattaat tgaaaaaatg tatggtcacc actatacgcc acaaacaatc tccaacatga
      541 gtaaattggt ggctgaagat gttttagctt ttaaagaaag aacgttagaa gccaattatt
      601 ccgttatatt tatggatgcg acgcatatcc ctgtgaagcg acagactgtt tcgaaggaag
      661 cagtgtatat tacgattggt attcgtttgg atggaaccaa agaagttctt gggtttacta
      721 ttgccccaac tgagtctgct tatatttgga aagaagttct tcaagatctt agaaaacgtg
      781 ggttagaaga agttttatta gtagtgacag acggattaag ctgtattgaa gaaagtatcc
      841 atagtgtgta tccgaatgcc caatttcaac aatgttgtgt gcatgtatct agaaatatcg
      901 ctcataaagt tcgtgttcga ggtcgaaaag aaatttgtga ggatttcaaa ttggtttacc
      961 aagcgaattc aaaagaagag gcattggatc acatcgactt tatgactagg aaatggaaaa
     1021 agcagtatcc aagagtcgtc aatttactct tgaatcctgc cctattaacc ttttataatt
     1081 tccctcacgc catcagacga acaatttatt cgacgaacct gattgaaggc tttaataagc
     1141 agctaaaacg atatactcga agaaaagaac aattccctaa tgaagaatct ctagagagat
     1201 tcttcatttc tcaatttaat caatataacc aaaaattttt aggtagaatt cacaagggat
     1261 ttaaagaaat tcaggataca ttagagtcga tgatttaact gtaattaaca gaatggattt
     1321 tccatttaca tataattctt gacgctacca taatctaaat aaccatcata ttcatctact
     1381 acttatataa ttgagtttta ttaaactttt taagtttcta ttctatcaaa tatttaaaca
     1441 atctctgcat ccgaaaagac tacctcgtat agttttacta acaatatttt tattagcgtg
     1501 ttcaaatcct gatttcttgt atcaattatt ttctgttcac tttcaataag aaaaaagtct
     1561 ttacttccat ggataataat aagggttctg ttgcaaagtt ttaaataaag aataaaatcc
     1621 cttacggtat ctatgattta agctgggatt cccaataata ccttgatttc agtacagacc
     1681 gaaaacccga agagagtgcc ttcttttcgg gttttcttat ataatcctc
//
LOCUS       DARPZJ010000147         1686 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.156, whole genome shotgun sequence.
ACCESSION   DARPZJ010000147 DARPZJ010000000
VERSION     DARPZJ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.156"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(45..779)
                     /locus_tag="SLE23_002881"
     CDS             complement(45..779)
                     /locus_tag="SLE23_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEI8469697.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="SLE23_002882"
     CDS             1106..1516
                     /locus_tag="SLE23_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HEI8469698.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..>1686
                     /locus_tag="SLE23_002883"
     CDS             1509..>1686
                     /locus_tag="SLE23_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEI8469699.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYN"
BASE COUNT          537 a          294 c          325 g          530 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataata
//
LOCUS       DARPZJ010000148         1648 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.157, whole genome shotgun sequence.
ACCESSION   DARPZJ010000148 DARPZJ010000000
VERSION     DARPZJ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.157"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            97..390
                     /locus_tag="SLE23_002884"
     CDS             97..390
                     /locus_tag="SLE23_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469700.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            387..611
                     /locus_tag="SLE23_002885"
     CDS             387..611
                     /locus_tag="SLE23_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEI8469701.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            608..1633
                     /locus_tag="SLE23_002886"
     CDS             608..1633
                     /locus_tag="SLE23_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEI8469702.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPQR"
BASE COUNT          575 a          264 c          339 g          470 t
ORIGIN      
        1 tatgcattac agacgaagaa gcagataaaa tcattagcaa agaagagagc gcatcttaat
       61 tgatgtgctt tttattttga ttcaaggagt tgtcacatga ttaatttagg ggaatgggga
      121 gcgatagcag gatcaataac cgctatcgtt tctttgattt tattagtaat aaaaccaatt
      181 actgcatctt tctcgaagat tactgagact ctttcaaaag taagtcacaa tttagatttg
      241 ctgactaaag atttagaatc gagcaaatca gatcgattga tgattcatga agaactaaag
      301 aaacacgatg aaagattaga tacacatgca gaaaaattgg tagaacacac gcaacaaatt
      361 aaaactttat ttagggagag aagaaaatga ataataaaac gttcgaagta ctaaaatggt
      421 tcgcactggt aattattccc gcactagcta ctttcgtggg gttagttggt aaagcgctca
      481 attggcagta cacagatatc tgtgttgtca tcattactgg ttttggcgcg tttttaggga
      541 gtgtgttggg tgtatcaaat cgaacctaca aaatgttctc ggctgaaagc gaagaaggag
      601 gaaacaaatg aaaaagaaaa ttactattac tgcgatgagc ctgttaacgg ctcttttttt
      661 attacccatt aatacgtttg cttatactat taatgacgag tataatttag cgccgaatca
      721 aggagactcc agattagcaa ttcctaacaa aattattttg cacgaaactg gaatagatgc
      781 accagcaaga aacgtagccg ccaacatgaa aaataattat aacggaagca attcttatac
      841 tacagatgtt attggtgacg gtgggattgt ttaccgtgtg ggtgagcaag gatatgtttc
      901 gtggggagct ggtaacgcta atccttatgc gcctgtacag attgaattac agcgcacata
      961 tgataaagca ttgtttgaaa aaaactatcg agcttatatt gaatatacaa gagatagtgc
     1021 aaaaaaatat ggaattccat tgactcttga tcaaggaact tctttattta caaaaggaat
     1081 catttctcat ttgtgggtga caaattatgt ttgggggaac cacacagatc catatggtta
     1141 cttatcgcaa atgggagtta gcaaagaaaa gcttgcttat gatttagctc atggatttac
     1201 cgatgaaaat ccaactactt cagatgataa accagtcatt gatccaacta gagcaggtgc
     1261 agcaaatcct acgctgacag atggaacaaa tcacgcccac attgatcagt ttggagaaat
     1321 cgaaaacgca aacttgcatg tggctggatg gcacattgct aattataaat acgagtatat
     1381 tttcattatg gattacaata ctggaaaaga attagctcga gtaagagctg atggaattta
     1441 tagaccagat gtaaatcaag cttataatac ttctggaaac gttggttatc atgtatcttt
     1501 caatatgcgt aattttccta ataagaaagt ctatgtaatg atgcgtgcaa cgaatgatcc
     1561 agaagggaac actaaaggcg gagcacaaga ttttcatgat aaacgctggt atttaaatat
     1621 tccgcaacga taaaaaaagc ccctcgat
//
LOCUS       DARPZJ010000149         1622 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.158, whole genome shotgun sequence.
ACCESSION   DARPZJ010000149 DARPZJ010000000
VERSION     DARPZJ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.158"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            216..722
                     /locus_tag="SLE23_002887"
     CDS             216..722
                     /locus_tag="SLE23_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469703.1"
                     /translation="MDIKWLVQQNDSNLELAIKYLEETIFEDEHLTDNFLQVLKYLEI
                     YSVKKNKLIGENDSPIKTPIELSLRNRMGILQRSEIVKELFYHKFSYEIRLDDTYEHY
                     RIVFFVYNSIEDATATTALTFGFTKNGTINSDKTRQAATESDDICKKVCNGEENYWIG
                     EEKLNEIY"
     gene            709..1161
                     /locus_tag="SLE23_002888"
     CDS             709..1161
                     /locus_tag="SLE23_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469704.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            1154..1552
                     /locus_tag="SLE23_002889"
     CDS             1154..1552
                     /locus_tag="SLE23_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469705.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
BASE COUNT          644 a          190 c          270 g          518 t
ORIGIN      
        1 cgtaaactag tttggtaata caattgtaat ttattttcag tatttaaaca tttctacctt
       61 attacattat gttaactaaa ttgcttataa aataagctaa tttttattga caagcaggat
      121 gtactatagt taaacttaaa ataagataca aatatatata atatgcttat acatatagta
      181 atatttacta atattgaaac aggtggttta gtgagatgga cattaagtgg ttggttcaac
      241 aaaatgatag caatttagaa ttggcgatta aatatctcga agaaactatc tttgaagatg
      301 aacatcttac agataatttt ttacaagtat taaaatatct tgaaatttac tctgttaaaa
      361 aaaataaatt aattggtgaa aatgattctc caataaaaac acctattgag ctaagcttaa
      421 gaaatcggat gggaatactc caaagatcgg aaatagtaaa agaacttttt tatcataaat
      481 ttagttatga aataagacta gatgatactt atgagcatta tagaattgtt tttttcgtat
      541 acaattctat agaagatgct actgcgacta ctgcattaac attcggtttt acgaaaaatg
      601 gaacaatcaa ttcggataaa acccgtcaag ctgctacaga aagtgatgat atatgtaaga
      661 aagtatgcaa tggggaagag aattactgga taggggagga aaagttgaat gaaatctatt
      721 aatgatttat taaaaaaaca tcctgattta tataaaaaat taaattctga acaaagaaac
      781 ctgtccaaac aattacttaa aataagatta aaaaaacaaa aaaacgtgac agaattctca
      841 aaaatgttag gaataagtga aaaaaaatat cttgaatttg agttcggaga tatgcatatt
      901 cctgttgcag agtacaataa acttttgaaa caagttgaaa atttgtccta taaagattca
      961 atgaatttca ctattaaggt tgctggcggc cctattaaat atgaccgtat tgaaaataaa
     1021 ccttatattc ggaataaaag ttactcagta tttaaaagta gaaagagaaa agaagtatcg
     1081 tcaaatatgg tctatgctag tgttaattac caagatacga gccgctatat tgtagaaaaa
     1141 gaggtatatg tacatggata aaggaaatag tgttactttt gcacttgaaa atattagttt
     1201 gaataaaatt cattttgaat taactgataa ttttagttat ggagatttag agtttaatat
     1261 tgaacttgga tataaagaag acgaagcaga gtatctagaa aaaaaacttg tttctttacg
     1321 agctcacatt gtagggggga tggaaggagc accggtagat attttactct tttcagttat
     1381 tcgtgtttct acaaatgaac agccatataa aaaattagta gaagaatcta tgggagagct
     1441 agctaaacct atcctgaata aagcttctaa tttgatttct aatttatata gcgaagtagg
     1501 agttatgcct acagttattg atttatatca gctatatagt caacaaaaat aaaatacaag
     1561 taatagagtt atctatttaa atttgcaaga caaagacctc aaccagtcat ccttggttga
     1621 gg
//
LOCUS       DARPZJ010000150         1584 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.159, whole genome shotgun sequence.
ACCESSION   DARPZJ010000150 DARPZJ010000000
VERSION     DARPZJ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.159"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            292..1479
                     /locus_tag="SLE23_002890"
     CDS             292..1479
                     /locus_tag="SLE23_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEI8469706.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          467 a          296 c          316 g          505 t
ORIGIN      
        1 ttttaacctt ccggttttga ttggataacc ctatgaacca tcgttatttt aatttggtat
       61 taactcattt cttttgagat aatatattta ttggattgag aggctaagcc gttcccccct
      121 tgggccattg aacccgcact cgagagactg gctcctctct ctgataagtg gattgcgtat
      181 gagttagatg ttgaaagtcc ttactttact ccgtatctcg tacaaggtag tgacgctttt
      241 cagttgagtg gatttcaatc caaaattctt tttttgaaag gtcagatata catgtacttt
      301 ttaggcattg atatcggtaa acgcactcac gttgcttcta tcatgaacga ggaaggaaag
      361 gtattactaa aaggtttttc atttcctaac accactgaag gagcagagtc attaattgag
      421 cgaatggtcg actattccgg agcacccagt gactttgtta tagggatgga agccacgggg
      481 cactattggc tgtccatctt ttcatacctt cacgaatcag attatttgat tcacgttgtg
      541 aatccccttc aaacagacgg atggcgtaaa ggtacagaaa tacggaaacg aaaaaacgat
      601 attattgatt ctgttttgat tgctgactta atgcgctatg gctcatttgt cgaaacggtc
      661 ttatccgatg aaaatgtttt ttctttgaaa caactttctc gttaccgaac ttatttagta
      721 ggtacagcga gcgacttcaa aagaaaaatt atagccgtat tggatcaagt ctttccagaa
      781 tacgcgacga tttttaccaa gcagggcgtt ttcggaaaag cttctaaaga gttattgctg
      841 gcgtttagtg ccccgatcga cttagaaaac atttcctcag aaactttggc ccaatactta
      901 gctgagttaa gcaggaaccg aatcaaggca gaaaaagcgg accaattgaa gcaagcagct
      961 tctaactcct ttggagtaaa atttgctcaa gaagcgttca ccttccaact acgttcaatg
     1021 attgaacaat taaaattcat tgaaagccaa ataaaggaaa cggaaagaga aatcaagcac
     1081 ataatggaca ctttaaattc tgttattctc acaattcctg gaattggtcc tataaacggt
     1141 gcgactattc ttggtgagat cggagatatt caaaaatttt ctaacccgaa aaaactcgtt
     1201 gcttacgctg ggatagacgc ttccgtgaca caatcagggc aatatgaggc aacgcataat
     1261 gttatgagta aacgagggtc tccatatttg cgaaaagcct tgttttcggc ggctttagta
     1321 gcttctcaat gtgatcctgt ttttagtgcg ttttaccaga aaaaagtttc cgaaggaaaa
     1381 catcatctaa ctgccttagg tgcggtttct cgtaagcttt gttacgtgat tcatgctatt
     1441 ttgactaaaa acgagcctta tataattgtt tctgattagc tattgaacat tcaaaaaaac
     1501 taatggtaag aagcttattt gttgtaccct tttttcggaa ttatctgtta taaaatattt
     1561 tttgatttgg ctaattttta cttg
//
LOCUS       DARPZJ010000151         1577 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.160, whole genome shotgun sequence.
ACCESSION   DARPZJ010000151 DARPZJ010000000
VERSION     DARPZJ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.160"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            535..1554
                     /locus_tag="SLE23_002891"
     CDS             535..1554
                     /locus_tag="SLE23_002891"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEI8469707.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT          541 a          257 c          332 g          447 t
ORIGIN      
        1 attttttgca ttatctacag ttcaacttat aatctgttta atgggacatg tgggtgccaa
       61 ccattttttg ttatgcaata gtactattta gttgttgcat ggatccgtag taaaagtcca
      121 agtacaacga gttgcgccag tttacatagc gttttgtatc cagaatgttg actaaaacaa
      181 aagttcctat gtcaaccgtc aacagagaca atctgtccgt tgcaggacct gacagattta
      241 gaaatgttca atctgtctct tatgtatttt aaatcaatac tcactaggag aagtttccta
      301 acctcctaat agtaatgctg gtagtaacat tgtcaaaact gcttcctctt aggaacaagc
      361 aaagcataac gagtgtaaaa ataaaatgta gactattgta acatatcatt gattatttca
      421 agtaaaaacg ataaaagaag taaacaaaca cttaaaaaca atggaaatta gtcccaactt
      481 taagaaatgt atactataat ggaaattatc aattatttat ttggaggaat atccatgaaa
      541 caaaaaatcg cagttcttgg tcctggatct tggggcactg ctttagcaca aacattggca
      601 gaaaacgggc atgatgtccg tatttgggga aatgtacctg aacagattga tgaaatcaat
      661 aagtatcata caaatcagca ttttttacct gatttgacga tcccagaatc gattatcgga
      721 tataaagaat tggcagaagc agtggataac gcagatgcta ttttatttgt tgttccaaca
      781 aaagcgattc gttcagtcgc acaggaactt attggtaaaa tgaatactaa gccaatcatt
      841 atacatgcaa gtaaaggact agaacaagat acgcataaac gaatctcaga agttttggct
      901 gaagaaattc cagaagaaaa aagacaggca attgttgtat tatctggtcc tagccatgct
      961 gaggaagtgg cagtacatga tatcacaaca attacagctg caagtattga tcaaaaagca
     1021 gcagcctatg tacaaaaact gttcatgaat gattatttca ggatttatac aaataatgat
     1081 gtgattggcg tagaaactgg tgcagcactg aaaaatatca ttgcaattgg tgccggcgct
     1141 atccatggat taggattcgg agatgatgca aaagcagcaa tcatgactcg aggattggca
     1201 gaaatcagcc gtcttggtgt cgcgatgggt gccaatcctc tgacatttat cggtttgagt
     1261 ggtgtggggg acttgatcgt tacttgtaca agtgttcatt ctcgcaattg gcgtgccggt
     1321 aacttgttag gacagggaca taagctggaa gaagttctag aaaacatggg aatggtcgtt
     1381 gagggtgtgg caacgacaaa agcagcagta gagctagctc aacagctagg tgttgagatg
     1441 ccaattactc aaacaatcta taatgttttg tataatggag aagatatcaa aaaagcagca
     1501 aaagaaatca tgttacgtga cggaaaaatg gagaatgaat tttctcttcg ttaaatagat
     1561 gatcaatagt taatcgt
//
LOCUS       DARPZJ010000152         1504 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.161, whole genome shotgun sequence.
ACCESSION   DARPZJ010000152 DARPZJ010000000
VERSION     DARPZJ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.161"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(312..611)
                     /locus_tag="SLE23_002892"
     CDS             complement(312..611)
                     /locus_tag="SLE23_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469708.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(617..847)
                     /locus_tag="SLE23_002893"
     CDS             complement(617..847)
                     /locus_tag="SLE23_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469709.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1097..1297)
                     /locus_tag="SLE23_002894"
     CDS             complement(1097..1297)
                     /locus_tag="SLE23_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEI8469710.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          535 a          243 c          219 g          507 t
ORIGIN      
        1 attgtgagat aataataaag aagagtttaa agcgttcccc aaaaaccact gccccataag
       61 tgtgttacgc tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga
      121 aaaaaagtga gaaaaaaggc ttataattgg agtggtagtt aattagtgac ttatttttga
      181 ttttatagca ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa
      241 cttaaaaaat atctcctttc ataagtatgg tgataaaatc cgttccgggc taccttttta
      301 ggtagcctac tttaatcttt gtatctttct ggatcaacga aagtatactt tatatagtca
      361 taacgccgat gatcgcttcg agcgtctagc acatcagtca cgatatcaaa caaaaaatat
      421 acgtctttct tcattctagt tttcgcagca gggattttaa agtagttctt attagaatag
      481 tagagattaa ttaataagct atcttcgatt gctaaaaaga aaacttctga atcccacacc
      541 ttataaaaat ctttgacaaa tctattcgaa ggatcaaatt taaaccataa ttgcgtctca
      601 ttaaaaagca taaccattac tccgatctat ttttaaactt agtctctacc tctaatatat
      661 atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt acaggttgtt
      721 tattttcgga aaaagctaat atagctaaaa ttgaaacatc catctggaat ttgtcttttt
      781 cgttgctttg ctcataaaaa tctgcatatt catcactaat attttttcta ataaattctt
      841 ccatcataaa gatcacctcg aaaagagtat acgaacaaac gttctttttg taaaggtgga
      901 atttattata ctaaataaat aggtgaacaa gtacttgtgc caaattatgt gccaaaaaaa
      961 atcgaattta ataaaacaca aacaaaaaga aatcctatta tgataacatt tcttataata
     1021 acaaacacaa cagaagacgt gtaatagtta gtcaggaacg tacaaataac ccctgtatcc
     1081 tttgcggtac agggggttat tttgtataag tagacattgt agtttctaaa ctgctatgtc
     1141 ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgcg
     1201 tatgtcttag tccatcaata aacagtcgaa gagaaaatag ggaaaaattg attactaaag
     1261 aaaaacttac taggtcgacg gtgtagttga ttttcatact tcaatagatt cgaattaaac
     1321 gatttcgatt ggcttatacc agtcctatcc aacgaaagat atatcgttct taactctagc
     1381 ggtataactt gaagctttac gtaaagccaa tgggaatgaa ctggagatga ctttttatta
     1441 tttttagtaa tagctgatgg gttaatactt acaactttcc ttttcaaagt accatataaa
     1501 aaaa
//
LOCUS       DARPZJ010000153         1457 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.163, whole genome shotgun sequence.
ACCESSION   DARPZJ010000153 DARPZJ010000000
VERSION     DARPZJ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.163"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            109..1041
                     /locus_tag="SLE23_002895"
     CDS             109..1041
                     /locus_tag="SLE23_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEI8469711.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1113..>1457
                     /locus_tag="SLE23_002896"
     CDS             1113..>1457
                     /locus_tag="SLE23_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469712.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          228 g          420 t
ORIGIN      
        1 gatgaaataa atcaaaagta tgatgaaaca ttaaaaaatg tctattcttc acttatcgtt
       61 tcaaatatag aagaaacttc atcttctgaa ataaaaaata agctttcttt gttaaaatta
      121 aaagaaaagg aatatattat tgacgatgct gtttctgtcc ctcttatttt aaataaacga
      181 gagaaaaata atttaaagaa aaaaatgctc attccatttg attcagaagt gaaaggatta
      241 ctcaataaac taactatttc taatatagac tcgactaggg aaaaaatcat aaaaatattt
      301 gataaaatta ataatttatt caagaatgac aatgctgaat taaggaaggg tcttttagag
      361 tttaaacttc aagaactaga acttcattac tcttatttag tgaaaattac cgaagaaaaa
      421 gaacaacaaa aagcaataaa agaacagatg atagaagagg aaaaagttcg tagagaaatt
      481 gatcgtgaaa agaaacgtat tgataaagaa caacgtcaat tcaattctga aatttccaaa
      541 ttaatcgcat atatgcaaaa agctaatgca gatgtggaaa aagaattata tgcaaataaa
      601 attcaagaac tggaagaaaa attaaaagaa ttagaagtta tacgtgaaaa tgtattacaa
      661 agagaattaa atactagagc cggttatgtg tatgtaatta gtaatattgg gtcttttggt
      721 gaagacatat ataaaattgg tatgactaga agattagaac ctatggatag aataaaagaa
      781 ttgagtagtg catcggttcc atttgaattt gacgttcatg cgatgatttt ttcagaggac
      841 gctccgtctt tggaaactaa attgcataat cattttagaa aacaagaagt taataaaatt
      901 aatcaaagaa aagaattttt caaagtttca ctagacgaaa tagagaaagt tgttttagaa
      961 aattataatg gaacagtaac atttacaaaa ttagctaaag ctgaacaata tagacgatct
     1021 ttagaattgt caaaagatta aatatataaa aagccttcgg gctttttctt ttaacaatta
     1081 ataggaacgt atattcgaaa ggaatagaaa taatgtggtt agaaaaaata aatgacaaaa
     1141 aatttaagta caccgaacgt tatacggatc ccttaactga aaaaaagaga aaagtgtccg
     1201 ttactttatc tagcaattca cgccaagctt ggaatcaagc taacttactt ttgaatgaaa
     1261 aaatcgcaga aaaaataaaa cgaaatgaag aattaccact aacttttgga gaattaaaaa
     1321 ctaaatggga tgaaaaatac aagccaactg taaaagaaag ttcctatcga acaactcagg
     1381 tttatctatc attaatttca aaatatataa aagatgatgt acttgtaaaa aacgttaata
     1441 gtaatcttat acaagat
//
LOCUS       DARPZJ010000154         1417 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.164, whole genome shotgun sequence.
ACCESSION   DARPZJ010000154 DARPZJ010000000
VERSION     DARPZJ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.164"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            92..1384
                     /locus_tag="SLE23_002897"
     CDS             92..1384
                     /locus_tag="SLE23_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8469713.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          460 a          289 c          257 g          411 t
ORIGIN      
        1 gcatcttttt tattttccaa aacatataga aaagacacct tgaaatcctt tagaattaat
       61 ttggcgaacc aacccaaaag gaggaatcaa gatgtcttac actcacctta tcaaagaaac
      121 attagatatt ctagacttat cagttacttt taacgaaaat tgtctcacaa aagaaaaata
      181 caaagggcaa atctgtcata tttatcgtgg aaacttgatt tatacagccc aagaatgcat
      241 ccactgtaaa caccagattg cttcagatat tgtgcgttgg ggtacaacaa ccgtccggtt
      301 gttaatgaac gatgtttctg aataccgtac ctacctcgaa ttgaaaaagc aacgcttcaa
      361 atgcaaagct tgtcagcgga cctttgtcgc agatacttct gttgcgaaaa aacattgttt
      421 catcagtgag aaagtccgct ggtctgtcgt gactcgtctg aaaaaaaata cctcaatgac
      481 agagatcgcc gctcagaaaa atctatcggt ctcttctgtt taccgtatta tgaagcgatt
      541 ttatcgtccg ttgaatcctt ttcggacacc gttacctaag gtactttgtt ttgatgaatt
      601 caaatcagtt cggggtgttt caggtgctat gagtttcatc atgatggatg gacaaacaca
      661 gcgcttattg gacattgtcg agaaccgaca actgcctttt ttaaaacgtt attttagtca
      721 tttttcacga gaaattcgtg aagcggtcga atggatcgtg attgatatgt acgctcctta
      781 tgtatcgctc gttaaaaagc tgtttccaaa agcacagctg attattgacc ggtttcacat
      841 cgtccaacat attggtcgta cctttcgcaa tcatcgaatc aaagaaacga accaactatt
      901 aaaaagcaaa gaacaaaaac actatcaatt aggtaagcaa ttaaaaagat actggaaact
      961 tcttcaaaaa gatgaacgca agcttgatta tactcgacgc ctttggcgac ctggcttcaa
     1021 agctcattta acagagaccg atattgtgga tcgcttactg aaagggagcc ctgctttgcg
     1081 tgtaggctat cagttatatc aagactttct ttacgctgta aaggaacgag actacgtatc
     1141 gtttgaagaa ctacttacca ataatatcat gcttcccgaa ggctatcaga cgaccttgag
     1201 aacgttccag aaatttctgc cacaaatcaa aaatgcttta caacaaagtt attcaaatgg
     1261 cccacttgaa tgtctgaaca accatatcaa agtgttaaaa cgaaatgcat atggctttcg
     1321 tagcttttat aatttcaaat tgcgcatcat gattcgtcat ggcaacgcat tgattttcaa
     1381 ctaaaaaaga tcaagaggaa ctgatccact tgatctc
//
LOCUS       DARPZJ010000155         1406 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.165, whole genome shotgun sequence.
ACCESSION   DARPZJ010000155 DARPZJ010000000
VERSION     DARPZJ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.165"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(182..255)
                     /locus_tag="SLE23_002898"
     tRNA            complement(182..255)
                     /locus_tag="SLE23_002898"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(219..221),aa:Ile,seq:cat)
     gene            complement(444..1403)
                     /locus_tag="SLE23_002899"
     CDS             complement(444..1403)
                     /locus_tag="SLE23_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HEI8469714.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          416 a          279 c          255 g          456 t
ORIGIN      
        1 taaaaatcaa agtaaaactt ttcaaatata cagaaatata actatgtgaa acatcctttc
       61 attaatccat aaaaggatac ataaaaaagc cactcatttg agtggcaatg aagaaaagct
      121 ttagcttgta taatactctt caaaaaattc taacacagaa cgattcaaat ggctacgtta
      181 atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg ctctgaccaa
      241 ctgagctaag ggtactggtt gttgccacat aaagccataa acaatcaacc agtagaatgt
      301 gtggcaacaa acctgttatc gcatagcttg gagtgtgact attatgggtg atagtgaaga
      361 tatgcgataa catcactatt ttatcgaatg atttttatag ttgtcaatat agttatgtaa
      421 tgctcctcaa cgaggagcta tttttatcgt ttaggaatat ttaaatacca acgtttgtca
      481 tggaaatctt gcgcaccgcc tttagtgttt ccctctggat cattcgttgc ccgcatcatg
      541 acatagactt tcttattagg gaagttacgc atgttaaaag atacatgata gccaacattt
      601 ccagaagtat tataagcttg atttacatct gatctataaa ttccatcagc tcttactcga
      661 gctaattctt tcccagtatt gtaatccata atgaagatat actcgtattt atagttagca
      721 atgtgccatc cagctacatg caaatttgca ttttcgattt ctccaaactg atcaatgtgg
      781 gcgtaattcg ttccatctgt cagtgtagga ttagctgcac cagctcgtgt tggatcaatg
      841 acaggcttgt tttcagaagt tgttggattt tcatcggtaa atccatgagc taaatcatat
      901 gctaattttt ctttacttac gcccatttca gaaagataac cgtaaggatc tgtatgatcg
      961 ccccagatgt tttgtgttac ccataaatgc gatttgattc ccggttggtt ataaggagtg
     1021 tccaacgtta atggaatacc atatttcatt gctgaatctc tagccaattc aacgtatgcc
     1081 ttgtagtttt tctcaaacgt tgctttatca tgtgtgtgtt gtaactcaat ctgcacagga
     1141 ctgttggcat tagcatacga accagcaccg tactgtacat aaccaggttg accgacttga
     1201 taaacaattc cgccgtctcc cacaatataa gcagtataag cgctagtcca tgaacgttgc
     1261 atatactgcg cttcattgcg tcctgttgct gtttcattag ccgtttcatg cagtaaaata
     1321 tactgattat ttgctacttg tgagctacct tcatttgcgc ccaaattaaa ttcattgttg
     1381 atagtatagg caaatccgtt aattgg
//
LOCUS       DARPZJ010000156         1394 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.166, whole genome shotgun sequence.
ACCESSION   DARPZJ010000156 DARPZJ010000000
VERSION     DARPZJ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.166"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..397
                     /locus_tag="SLE23_002900"
     CDS             <1..397
                     /locus_tag="SLE23_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469715.1"
                     /translation="HWNAIEGKPTTVKGDKGDPGQAATITIGTVSSGSTASVTNVGTS
                     SAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDKTKLDGIAAGAQKNPGNAT
                     TTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            397..891
                     /locus_tag="SLE23_002901"
     CDS             397..891
                     /locus_tag="SLE23_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469716.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            905..1336
                     /locus_tag="SLE23_002902"
     CDS             905..1336
                     /locus_tag="SLE23_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469717.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          513 a          214 c          306 g          361 t
ORIGIN      
        1 tcattggaat gctatagaag gcaaaccaac aacggtgaag ggagataaag gcgatcctgg
       61 ccaagcagca acaattacca taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa
      121 tgtaggaaca tcatctgcag ctagatttaa ttttgtttta ccaaagggag ataaaggtga
      181 tcctggaata aatgccacaa ctacagctgt agctacaact acagcaaatg ggttgatgtc
      241 gtccacagat aaaactaagt tggatggaat tgcagctgga gcacagaaaa atccaggtaa
      301 tgctacaact acgacagcag gtttaatgtc agcaaccgat aaagtgaaac ttgatggatt
      361 agcgaatatt acatttgaga aagtggggac ggtttaatgg ctgatattgt tcaattaaaa
      421 gaagacggag ttgctaaata cttaaaaacg catgtagaag ctattgatgg taaagaagca
      481 ttggtgcaga cagatggaga ccaagccatt gcaggacata agaatttttc aggttctgta
      541 acaatcaata ataaacgtgt tttgacgact gatgataaca gatatgaagt ggtaaatctg
      601 gttgtcacta acggtaatac agggacagca aagctttatc gtgaaggaaa aacagtttct
      661 atatattttg tggctttaaa cggaaaaagt agtggcggga atgattcggt tattttaact
      721 gttccagaag gctatcggac accaattagt tttgaacaac tggttgggtc aatagaccgt
      781 tctactttga acagtgctca actatctatt ggcgcagacg gagccattaa atggagaaga
      841 aattcaagtt atggatcagc ttattcattt gttatcactt attcaattta agggaggaaa
      901 tctaatgaaa gtagtttaca aatcaatcaa gccttacgga ttcgagcaaa tcattttgaa
      961 caatcaagaa aatatccctg aaaactgtac agagattaaa ccaccagttc ctaactggag
     1021 accaagattt gattttgata aaaaacagtg ggttgagtta gctactgaag aagagaaaaa
     1081 agggaatgct gttgatagcg tagatgaatt ggctaatatt aaggcattat acgaaacgct
     1141 gaaggcagaa aatgatgaat tgaaacagct aaattctaaa gcaatgctaa acaatgtagc
     1201 aatcaagcaa gaaaatgtct tattgaaaga aaagtcagaa agtttagcgc agttgaattc
     1261 aaaaacgatg cttgcttctg tacaaaatac caaggaaatc gaagaaatca aaaaacaatt
     1321 acaaggtggg aagtaacatg tattcatatg aagatatcaa actaatgtat gactggggct
     1381 gtttcactaa cgaa
//
LOCUS       DARPZJ010000157         1383 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.167, whole genome shotgun sequence.
ACCESSION   DARPZJ010000157 DARPZJ010000000
VERSION     DARPZJ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.167"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            37..1338
                     /locus_tag="SLE23_002903"
     CDS             37..1338
                     /locus_tag="SLE23_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8469718.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          448 a          280 c          253 g          402 t
ORIGIN      
        1 ttgaatcacc acaacacaat caaaggagcg ttctgtatgc ctgatcttca tcatatcaaa
       61 ctactacttg gaatcaaaga taaaaacatt ttcatcacaa atgtggaatc gaagagcatt
      121 aagaatatca agagtcttgt tgtttctgcg acgttaagta aagaaattcg tcgctgtcct
      181 ttgtgtaaac agatgaatca tgaaggcatg atcgttaaga acggaaagaa aaaatcgctc
      241 attcaactta ataaatgtgc gaaccaactg acttatcttg ctttagcgaa acaacgctac
      301 cactgtcgtg gctgccacac ctattttacg gcgaatacct acattgtcga tagaaactgc
      361 tttatcgcta aacaagtgcg ctataaaatt ttagaagagc taactgaaaa acaagcaatg
      421 acgacaattg ctaagcattg cggcgtttct tggtcgaccg tttctcggac actcgcttct
      481 ctgatcccca tgacaaaagt aaaaagaaat tggttaccgc gttgtttatt aatggatgaa
      541 tttcgttcac tgaaaaatca agtcggtccc tactcctttt cttgtatgga tggcgatact
      601 ggaaaattac tggatattct tccttcacgg aagaaaaagg ctctcgtttc ttattttatg
      661 caatttgaac gacgcgcacg attgaaggta aaggtcatcg tgacggacat gaatgtttct
      721 tatgcctctc tgataaagga atgttttcca aaggcaaaac tcgttgtgga tcgttttcac
      781 attgtcaaac atctcattcg taaatttgag gatattcgcg tacgaatcat gaaaagcttt
      841 gatcgaaacg atccaacaca agccaaatat tatcgacaat taaaggcgtt gtctcggctt
      901 ctgatcaaac gacaggacaa gcttgtttat gacaaatgga ccaaatggcg caattttggt
      961 tgggcgtatc tcaccgaaag tgaagtggtg gatcgtctgc tttcgatctc tgacgaatta
     1021 cgaatcgcct atttttacta tcaagaaatt cttcaagcgt ttcacgacaa agaggcggac
     1081 actttcttta aacttgtaag aacgatgccc aattccgttc caaaagaact gcattctata
     1141 aaaaaagctt ttataaacta tgaatccggc attcgtttag ccctcgaatt gccttattca
     1201 aatgccaaaa tagaaaatct gcatacccac atcaaagcat tgaaacgagt cgcttatggc
     1261 tttcgaagct ttcggaaaat gaagaccaga attttcttac taaataatct gattacctat
     1321 gaatcaaaaa acatctaaag tagaaaagga attctacctt agatgttctt atctcactct
     1381 atc
//
LOCUS       DARPZJ010000158         1373 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.168, whole genome shotgun sequence.
ACCESSION   DARPZJ010000158 DARPZJ010000000
VERSION     DARPZJ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.168"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            191..445
                     /locus_tag="SLE23_002904"
     CDS             191..445
                     /locus_tag="SLE23_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8469719.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="SLE23_002905"
     CDS             446..763
                     /locus_tag="SLE23_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8469720.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          493 a          196 c          266 g          418 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaagacaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accttaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acttccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat ata
//
LOCUS       DARPZJ010000159         1352 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.169, whole genome shotgun sequence.
ACCESSION   DARPZJ010000159 DARPZJ010000000
VERSION     DARPZJ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.169"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            11..1350
                     /locus_tag="SLE23_002906"
     CDS             join(11..452,452..1350)
                     /locus_tag="SLE23_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HEI8469721.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          565 a          175 c          235 g          377 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DARPZJ010000160         1335 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.170, whole genome shotgun sequence.
ACCESSION   DARPZJ010000160 DARPZJ010000000
VERSION     DARPZJ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.170"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            209..751
                     /locus_tag="SLE23_002907"
     CDS             209..751
                     /locus_tag="SLE23_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469722.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            907..1257
                     /locus_tag="SLE23_002908"
                     /pseudo
     CDS             907..1257
                     /locus_tag="SLE23_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414636.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
BASE COUNT          537 a          157 c          258 g          383 t
ORIGIN      
        1 ccgattcaaa ttgatgaagc agatcccaaa gggctgcttc atcaattttt tcgtaagtgt
       61 ccgtacactt actgtgcttg ctcatatatt aatcgatcat atactaatcg tgtaagaaca
      121 actttaagca taatacttat attgttatac catagtttgg aaaaataaaa aattatattt
      181 catcaacgtt tcataaaagg tgtgtagaat gttattgaaa gtagctataa aatgctattg
      241 tgtaaaaaat aaaggaggaa taatttatga aaaaatagta ccaagaggag catgcctatt
      301 acttgcatta tgtttgagct taagcgcagt tgggtgtcaa aaaagtaatg aaaacaataa
      361 aataaaagaa ggacaatcca taagttctga agaggaaggc atgtcaatta atgcaaatgg
      421 caaaaatgaa acttttaagc catcagatta tacattggag gcaaagaaag aatatgttta
      481 tgaatattta gggcttaaat ttaaactctc agacaaattt agaaattata tagctgataa
      541 aaagatagcg atgttagatg atcaaagtcc tatagataaa gaactaaagt atgctatttt
      601 gacatttgag aaaatgacag aagaacaaaa gaatgcagtt atagaaaaga tgggcgatgg
      661 atataaaaat tggcaaaatg agcttgaaag aattgggact attggtatat ttgaaaaaaa
      721 tacatcagaa gaaaaaaatc taaaattata aaatgtgata ctcatactaa aataggagtt
      781 tcaagtgatg gaaaatacga ttgctattta agcacaaata gcggagctga aagtaatctt
      841 cttgatgaat taaaaagaac tgagattcaa attatagata aaaaagaacg tcctaaaaat
      901 ggttttgtgc tatcagaaaa aactgattta gaaaatacag aagcatttaa caaagaatcg
      961 gttaaagatt tacgtaaact accaacaaag gacataaatg gcaaggattt tacaagtaaa
     1021 gattttgaga agtatgatct tactatggta aatgtatttg caacttggtg tacagcttgt
     1081 gtaaaggaaa ttcctgattt ggttgaggtt cagaatgaaa tgaaaagcaa gggtgtaaat
     1141 atcgttggag ttgttacaga tcctgttgat gataacggtg aaaacaagga agcaattgaa
     1201 aagtcaaagt taatacatga aaagacaaag gcttcatatc ctttcttaat gccagatgga
     1261 atggcaacac tttttttgac aaaaattata aggtgttgtg aatgctgcgg tgttatggct
     1321 ccgattgccc ttgac
//
LOCUS       DARPZJ010000161         1334 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.171, whole genome shotgun sequence.
ACCESSION   DARPZJ010000161 DARPZJ010000000
VERSION     DARPZJ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.171"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            15..1310
                     /locus_tag="SLE23_002909"
     CDS             15..1310
                     /locus_tag="SLE23_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEI8469723.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          418 a          264 c          258 g          394 t
ORIGIN      
        1 taggaggatt caagatgtct catactcagc ttatcaaaga taccctaaat attctagacc
       61 taaatatcta tttcgaggaa aattgtttaa ctaaagaaaa atacaaaggg caaatttgct
      121 tgatttacaa aggaactctt ctgtacaagc cagaagagtg ttcccattgt ctttgtgtcg
      181 tcccctctag gatcattcgt tgggggacga caaccgttcg gttgttactg aatgatgtgt
      241 ctgagtatcg cacttatctg gagctgaaga aacaacgatt taaatgtaag tcttgccaaa
      301 gaacattcgt agcggatacc tctgttgctg aaaaacactg tttcattagt caaaaagttc
      361 gttggtctgt cattgctcgc ttaaaagaga atacttccat gacggaaatc gctcgtcaga
      421 aaaatatttc cacttcttcg gtctatcgtg tcatgaagcg attctaccgc ccattgaatc
      481 ctttcaaaca gactttgcca aaggtcttat gctttgatga attcaaatcg gttcgaagtg
      541 ttgccagtgc aatgagtttt atcatgatgg acggacaaag ccatgcatta ttggatattg
      601 tcgaaaatcg acgcttgcct tatttagaac gctatttttc tcggttttca ttagcgactc
      661 gtgaagccgt tcaattgatt gttattgata tgtatgcgcc ttatgtttcg ttggtgaaaa
      721 agcttttccc gaatgctcag ttgatcatcg atcgtttcca catcgtccaa catattggca
      781 gaactttctt gaatcatcga gtgaaagaaa ccacggtacg acttaaagga aattcccact
      841 ctcaacgagg gttagggaaa aaattgaagc gctattggaa actcctacaa aaagaagaag
      901 caaagttaaa ctatgaaaaa cgggtttggc gtgccagttt taaagattat ttgactgaaa
      961 gtgagattgc cgatcgactg ttagctgctt gtcccaactt acgccaaggc tatcagttat
     1021 accaagacat tctttatgcg gtaaagaaaa gagatcagtc actatttgag gattgtttaa
     1081 ctagagacat tagcggtctg ccagaaacct atacaaccac tttacgaacg tttaaaaagt
     1141 ttctgccaca gatccaaaat gcgcttcact acagctattc aaacggacca ttggaatgct
     1201 taaacaacca catcaaagta ttaaaacgca atgcgtacgg ctttcgcaac ttttacaatt
     1261 tcaaactacg aattatgatt cgtcatggca aaacattttt aaccaaataa acagaacaga
     1321 aagaggtttt cttc
//
LOCUS       DARPZJ010000162         1315 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.172, whole genome shotgun sequence.
ACCESSION   DARPZJ010000162 DARPZJ010000000
VERSION     DARPZJ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.172"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..228
                     /locus_tag="SLE23_002910"
     CDS             <1..228
                     /locus_tag="SLE23_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469724.1"
                     /translation="GFESFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPN
                     EYDGLLGVIPSKKSQMNESKFMSIFNDVNLR"
     gene            450..>1315
                     /locus_tag="SLE23_002911"
     CDS             450..>1315
                     /locus_tag="SLE23_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEI8469725.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQTAVKERESVSDELGYISRQREE
                     NEREKALVASERA"
BASE COUNT          452 a          197 c          310 g          356 t
ORIGIN      
        1 gggtttgaat cttttgctga ttttgagcgg tggttatcgt caatttctga cgatcagcaa
       61 cacgaaaaat cagtggataa tgagtggctt gctgatgaaa aatcagcgcc aagcgaacga
      121 gattatccca atgaatatga cggcttactc ggagtgatac cgagtaaaaa aagtcagatg
      181 aatgagagta aatttatgtc aatttttaat gacgtgaatt tacgataagc tattattttg
      241 cgtgaagcaa aataaagcgt aaaaggagtt gagagcgtga cacgctttcg gctccttttt
      301 tcgttgtcac ttgtgacagc gaaatccctc ggagagcgtt tggaattgtg acagtcatgt
      361 cacaattagg aaaacgttac tctttgacaa agagtaacag aaaggtttac actcttttta
      421 ttagcgacag cgcgaaggag gggtctaact tggggtttag tatttcgttc aaaaagggaa
      481 caaagaatac aagcatttct cataataatc gtgagttaac tgatagccaa aaaatcaatg
      541 actggcataa gcatattgat ttcacaaaat cggatgaaaa tatctatttg gaacaaacaa
      601 atattcgtga aaaatatgaa gaattattcg gtgaagccgt agaaaaatat aatgcaaagc
      661 agaaaagagc cgatagaaaa atcgaggact atttagcaaa ggttcgcaag gataaaaaat
      721 tggaaccaca gcgagaattt atcgtgcaaa ttggtactct tgatgatttt cgtactactc
      781 gtgatgatgg ttcttctact ggcatatcgg aacaacaagc agaacaaaat cgagtgattg
      841 ccaacaaaat tttagttgag tatttcaaag aatttaaaga acggaatcct agtttatccg
      901 tctacaatgc tgttattcat aatgacgaag taagtccgca cctgcatttg aatattgttc
      961 ctgttgctga agggtataaa cggggtgttc aaaagcaacc aagttttaac aaagccttgc
     1021 aacagcaggg tttacgagca gataaagaga atggtcgagt gatttggaat aattttagga
     1081 atcaggaagt tgagtcaatt gaacgtttga tggcagattt tggttgggag cgtgagttag
     1141 tcggtactaa caaaatcaaa gatgttcacg aatataaaga aatcatgagc gagatttcag
     1201 aattgcgtca aacggccgta aaagagcgtg agagcgtttc tgatgagttg gggtatattt
     1261 ctaggcaaag agaagaaaac gagcgagaaa aggctctggt ggcttctgag agagc
//
LOCUS       DARPZJ010000163         1306 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.173, whole genome shotgun sequence.
ACCESSION   DARPZJ010000163 DARPZJ010000000
VERSION     DARPZJ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.173"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            241..314
                     /locus_tag="SLE23_002912"
     tRNA            241..314
                     /locus_tag="SLE23_002912"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:275..277,aa:Ile,seq:cat)
     gene            694..855
                     /locus_tag="SLE23_002913"
                     /pseudo
     CDS             694..855
                     /locus_tag="SLE23_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            1005..1205
                     /locus_tag="SLE23_002914"
     CDS             1005..1205
                     /locus_tag="SLE23_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEI8469726.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT          419 a          207 c          266 g          414 t
ORIGIN      
        1 ttttttgctc tgtaattaac tcgtatagat cctgcaagat agtttgtttc tgaataaatg
       61 attgatatga agtatttaga tgactgtatt gacaactata aaaatcattc gataaaatag
      121 tgatgttatc gcatatcttc actatcaccc ataatagtca cactccaagc tatgcgataa
      181 caggattgtt gccacacctt ctactggttg attgtttatg gctttatgtg gcaacaacct
      241 gtactcttag ctcagttggt cagagcagac ggctcataac cgtccggtcg taggttcgag
      301 tcctacaggg tacataattt aatctatttg ataaaaaata aaattcaata atggtataat
      361 aaaatgtcgg ctcgtcgctt ccacagagat tttcgtggga ggaggtgtat gatttgtttg
      421 aattcacttt ggagcacgtg ctcttgccat tgttaattgg tttaactttg gcattattta
      481 gtcattggct agataaacat tagagccgac aatggcgctt actgtttcgc agcggtaagc
      541 gtcttttttt gaaaaagaaa aaaacacaac gtattcgcag gtacgttgtg tttatggtgt
      601 atatttgttt aaattcactt tcaattatta ttatacttgt taaataaatt gtgtcaatat
      661 aaaagatatt tttatacgtg tactaaccta tattatcctt ctggtaatgt tattccatcg
      721 cagcaggata tgaattttac caaaaggata caaaagtgtg gagaaatgat ggggatcact
      781 gtactggacc acttgatcat cggacgcaaa cgatatttta gtttgagaga agaaggaatg
      841 atggaagaga agtaagttgc tttcttgcaa aaaaaatgaa gcaagtgtac aattatattg
      901 taattttgtt tgggaataga agttgaaaca tctgttgcac ctctatcgta cacgagcaat
      961 gttacaattt aaattagtgc ttttggcacg aggaggatat tattatggaa aacggaacag
     1021 taaaatggtt caacgctgaa aaaggatttg gatttatctc acgtgaagat ggaagcgacg
     1081 tattcgttca cttctcagct atccaaggtg acggattcaa aacattagaa gaaggtcaag
     1141 cagtgacttt cgacgttgaa gaatcagacc gcggcccaca agctgcaaac gttgtaaaag
     1201 cttaatttta tctgtaaatc aaattgatgg tagacatcaa tttttacgag agaacaaagc
     1261 gagtaacaaa aatacctgcc acaagagaca atttctcttg tggcag
//
LOCUS       DARPZJ010000164         1294 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.174, whole genome shotgun sequence.
ACCESSION   DARPZJ010000164 DARPZJ010000000
VERSION     DARPZJ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.174"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1244
                     /locus_tag="SLE23_002915"
     CDS             <1..1244
                     /locus_tag="SLE23_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEI8469727.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DARPZJ010000165         1293 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.175, whole genome shotgun sequence.
ACCESSION   DARPZJ010000165 DARPZJ010000000
VERSION     DARPZJ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.175"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(523..>1293)
                     /locus_tag="SLE23_002916"
     CDS             complement(523..>1293)
                     /locus_tag="SLE23_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEI8469728.1"
                     /translation="AFDFQTSQQNRLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFIL
                     EEVNDNSVTFSIKPNAEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFI
                     GAHPAFNSPLVEGENYEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDL
                     DYSLFSHDAITLDQLKSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPW
                     SGLSTSLEEGNFLEDKRQVTKISPQETSRKIYDITILN"
BASE COUNT          438 a          242 c          212 g          401 t
ORIGIN      
        1 cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta actttaactg
       61 ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac aatcggaata
      121 gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt gccattccaa
      181 aacgctatat ttaagatttc aaacaactat attaatagga agaaaatttc atttttcctc
      241 ttagttctat aaaaagtgtg gctaatttga ggcaaaatat taaattaaat ttgccacaaa
      301 ttaatggctc cactattatt ttaaatcaag aagtagtaaa taatcttatt ttttactacc
      361 agactgtctt tagatattag cttttcgtca cccactacag ttgacataga cccacaaaaa
      421 acttaaaaac cttgcgatgt aagactggca cggagaagac caatctatca tcacaaggta
      481 agagtattca aatcttattg aagactcaaa taataacaaa ttttaattaa ggatagtaat
      541 atcatagatt tttctagaag tttcttgagg tgaaattttc gttacctgtc ttttatcttc
      601 taagaaatta ccttcttcaa gtgaagtgga gagaccactc caaggttcca aagcaatgaa
      661 tggactttta ttagttgtag accacagaat caagttcgga aaatcatcaa aatctactcg
      721 aagaccttta ccagacttcc ttgaccgaag cgttacgcta cgagacttga gctggtcaag
      781 tgtaatggca tcatgggaaa aaagtgagta gtccaaatcg agaatttttt gattttccaa
      841 aaaaggtgtc cgatcttgca aatctaataa tcctgtctca ggaaaactct ttggtatcga
      901 gcaagactca acctcactaa attcaatata ataatcctca tagttttcac cttctactaa
      961 aggactattg aatgctggat gggctccaat aaagtaaggc attgtttttt ccatttccaa
     1021 gttcgttacc tgaaattcgg ttctaattga tttaccattc aaggtataaa caactctcag
     1081 ttcaaactga tataggtaat tatcaagcat ctcagcattt ggtttaatac taaaggtcac
     1141 gctattatca ttgacttctt ccagaataaa ttcttctttt cgaacaaaac catgtctacg
     1201 aataagacct gtaaaaaagg gtctttcttg aggtctataa atagcccaat catttcgtaa
     1261 acggttctgt tgcgaagttt gaaaatcaaa cgc
//
LOCUS       DARPZJ010000166         1290 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.176, whole genome shotgun sequence.
ACCESSION   DARPZJ010000166 DARPZJ010000000
VERSION     DARPZJ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.176"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>1290
                     /locus_tag="SLE23_002917"
     rRNA            <1..>1290
                     /locus_tag="SLE23_002917"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          344 a          286 c          392 g          268 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa
//
LOCUS       DARPZJ010000167         1288 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.177, whole genome shotgun sequence.
ACCESSION   DARPZJ010000167 DARPZJ010000000
VERSION     DARPZJ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.177"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            282..521
                     /locus_tag="SLE23_002918"
     CDS             282..521
                     /locus_tag="SLE23_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469729.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="SLE23_002919"
     CDS             complement(883..1143)
                     /locus_tag="SLE23_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469730.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
BASE COUNT          426 a          235 c          175 g          452 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctcttttt
//
LOCUS       DARPZJ010000168         1282 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.178, whole genome shotgun sequence.
ACCESSION   DARPZJ010000168 DARPZJ010000000
VERSION     DARPZJ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.178"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(78..1067)
                     /locus_tag="SLE23_002920"
     CDS             complement(78..1067)
                     /locus_tag="SLE23_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEI8469731.1"
                     /translation="MTDKKQDLINGTFKMKKKNLQKVIDFGGGRFSERTVERMASCGS
                     YLEFIATADKEKKKLIQANFCTNRFCPLCAWRKARKDSLMLSIMMQAIAEEKNYQFIF
                     MTLTTPNVKADKLNEEIDLFNHALSKMFRRKRVMGAIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDPKYYIKQAEWLDLWRDVTGKTGINLDGTDEISQLDIRKVKGFQQ
                     DKAVQELAKYSAKDFEMTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYEAGELDHY
                     KKKDENEYFWFLTASWMKKESSYAINLRELTPDERKFFSGGLVEEKPVEGENE"
BASE COUNT          353 a          298 c          198 g          433 t
ORIGIN      
        1 cccataaact acatcccctt ttccttggaa ttaataacag aaatttggtt taatcgttat
       61 tttatcaggt gaatcagtca ttcattttcc ccctcaacag gtttttcctc aactaaccca
      121 ccgctaaaaa atttcctctc atcaggcgtc aattctcgga gatttattgc atacgacgat
      181 tcctttttca tccatgaagc agtcaaaaac cagaaatatt cgttctcgtc ttttttcttg
      241 tagtgatcga gctcgcctgc ttcgtatttc ttcttgtact ccttgaagac cccgttaaac
      301 gtgattaact ggcgcccttt catagcatgg taaaacgtat caaagacttc ttggctctcg
      361 gtcatttcaa agtctttcgc agaatacttg gcaagttcct gtaccgcttt gtcttgttgg
      421 aatcctttga cctttcgaat atccaactga ctgatttcgt ctgtaccatc aagattgatt
      481 cccgttttcc cagtcacatc acgccacaaa tcaagccatt ctgcctgttt aatataatat
      541 ttagggtcag taaaatacga cttgttcacc gccaaaatca aatgaaaatg cgggttgtag
      601 tcatttcgtt tcttgttgta cgtgatttcc aatttccgga catagccttt aatcgcaccc
      661 atgacccttt tcctacgaaa cattttggac aacgcatgat taaataaatc aatttcttcg
      721 tttagcttgt ctgcttttac attgggcgtt gttagcgtca taaaaataaa ctggtaattc
      781 ttttcttcag cgattgcctg catcataatc gacaacatca acgaatcttt acgggctttg
      841 cgccatgcac acagcggaca aaagcgattc gtgcaaaaat tcgcctgaat caatttcttt
      901 ttctccttgt cagcggtggc gataaattcc aagtatgaac cacagctagc catacgctcc
      961 actgtccttt ccgaaaagcg cccgcccccg aaatcaatca ccttttgtaa atttttcttt
     1021 ttcattttga atgtcccatt tattaaatct tgttttttgt ctgtcatatt gatatactga
     1081 acctacaatt ttgtataaaa aggctgaaaa gccgataaca aaaaaaatag attgctctcc
     1141 ttaatttggt tggtttttac ttagacacta aaagcttaat ccaatatgct aggaaaagca
     1201 atcttttttt tgtgcaaccc cttatgtatc aaggtcaaaa gcatactata cgcaactatt
     1261 tcctgccgaa aataattgcg ta
//
LOCUS       DARPZJ010000169         1258 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.179, whole genome shotgun sequence.
ACCESSION   DARPZJ010000169 DARPZJ010000000
VERSION     DARPZJ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.179"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            76..>1258
                     /locus_tag="SLE23_002921"
     CDS             76..>1258
                     /locus_tag="SLE23_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HEI8469732.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KI"
BASE COUNT          420 a          247 c          242 g          349 t
ORIGIN      
        1 ggtattaaaa aacatatcgt tctctagtat gattaaatca ccacaaaata aacaactgag
       61 aggacgatac gctatatgaa tgattctatc aaaaaaatgc tgagaataac agagaaagat
      121 ttgatgatta cagaggtctc ttacgagacc cttcagaaga aaaagacgtt ggtcgtcgat
      181 gctgttctct cgcctactcc tcgtgcttgt agaagttgtg gttctactgt ggtagatgga
      241 aacgggaaag caattatagt gaaaaatgga aaaaaggaaa cgattgtccg ttttgaacaa
      301 tacaatcata tgcctttggt tatgcgccta aaaaagcaac gctatacctg taaaaactgt
      361 cgcacccatt ggacggctca aagttatttt gtccaaccca gacattcaat cgcaaatcat
      421 gttagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      481 agctgtcagg tatctttgac caccgttatt cgtacattga aagagtttaa aagctattta
      541 ccaaagcaat ctaagaagat cctccccaga gtattgatgg ttgacgaatt tcgttcgcat
      601 gcttccatag aagataagat gagctttatt tgcgcggatg gcgaaacagg aaaattaata
      661 gatgttttgc ctacgcgtaa attacctcga ttaacaagct atttcttagg ttgtaccaat
      721 ccagaagaag tagaattctt ggtgacagac atgaacgccg cctacttcca gctcaccaaa
      781 cgtgttctgc caaatgcgaa agtcgtgatt gatcggtttc atattgtcaa acacatgaat
      841 caagcgttca atgagttgcg tatccgtgaa atgaatgaac ttcgtaaagc cggacagaaa
      901 agccaggcag aaaaactgaa aaagaactgg cgctttttgc taaaaaatcg tgcaaacatc
      961 aaccattatg aatacaaaac atggaaaagt ttccgagcac caaaataccc atttcttact
     1021 gaagcaatga tgattgatcg attgcttgag ttttctccgc ccctaaagga ggcgtatccc
     1081 ttttttcatg aattagttga agcctttcga gacaaagacc ctgacttatt tttctcctta
     1141 ttggcagaac ttcccgaaac gttagatgac agctttcggg aaaagcttca aaaccttctg
     1201 acctatgaag aaggcatcac caacgcaatg atctatcctt attccaatgg aaaaatag
//
LOCUS       DARPZJ010000170         1236 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.180, whole genome shotgun sequence.
ACCESSION   DARPZJ010000170 DARPZJ010000000
VERSION     DARPZJ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.180"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..782
                     /locus_tag="SLE23_002922"
     CDS             <1..782
                     /locus_tag="SLE23_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEI8469733.1"
                     /translation="TKSFTEEVTAFKGRELHDRYAAIYMDATYIPLKRKTVAKEAIHI
                     AVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERGLKNVLLFITDGLKGMVGAISR
                     FYPKARFQHCCVHVFRNISHKVRVNNRKEVCDDFKMVYQASSKEVALEARGAFAKKWK
                     TSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIESFNKQIKKYSHRKEQFQNEES
                     MERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQPMEN"
BASE COUNT          400 a          223 c          245 g          368 t
ORIGIN      
        1 taacaaaatc atttacagaa gaggtaacgg cgtttaaagg gcgagagctt catgaccgtt
       61 atgctgctat ttatatggac gcaacgtata ttccgttaaa gcggaaaacc gtcgccaagg
      121 aagctattca tatcgcagtt ggcattcgcc cggacggatc aaaggaagta ttgagctatg
      181 cgattgcacc gactgaatcc atcacgattt gggaggaaat tttattagac cttcaagagc
      241 gcggtttgaa aaatgtcctc ctgttcatca cggatggctt aaaggggatg gtaggagcga
      301 ttagtcggtt ctatcccaaa gctcgttttc aacattgttg tgtacacgtt tttcgtaata
      361 tcagtcacaa agtgcgtgtc aataatcgta aggaagtctg tgatgatttt aaaatggtgt
      421 atcaagcctc atctaaagag gtggcgttag aagcacgtgg tgcttttgcg aaaaaatgga
      481 aaaccagcta tccaaaagtg gttgaatcga ttctttcgaa cgatcacttg ctcactttct
      541 atgatttccc cttggccata cgcaagagta tttattctac gaacttgatt gaatccttta
      601 ataagcaaat caagaaatac agccaccgca aggaacagtt ccaaaacgaa gagtcgatgg
      661 aacgtttctt agtctcgtct tttgatactt acaaccaaaa attcctaggt cgcagtcata
      721 aaggtttcca acaggccgaa ggcgagctcg aacaaatgct gagtcaaccg atggagaatt
      781 agaaacaatc tacagtaggg aagaaccatt tacacaaaat tattgacgct cccaagctaa
      841 aactcctatt aatcgatcta ctaaaaataa ataaaaaaat tcttttcaat tttatttatg
      901 gtatgacata aataaagtaa agttattctt ctaggttaat cttattaata ctctttctca
      961 ctagtgttgc atgcaacact agtgagaaag agtattaaat atactgcaag gcaagacatt
     1021 tggtaattga agaataacaa gcaaaaaaat agcagtcagg tctcttgaca aagtatagtt
     1081 gctattcttt ttttaggccc tactttaatg aaatttttgt ttggagggaa cgacttcatt
     1141 cctttgatta tttcagttga atttaataga gaagcctggc gtctattaag aaatactttt
     1201 cttgatgagc gtcaattttt ttaacggaaa tctatc
//
LOCUS       DARPZJ010000171         1215 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.181, whole genome shotgun sequence.
ACCESSION   DARPZJ010000171 DARPZJ010000000
VERSION     DARPZJ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.181"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            2..>1215
                     /locus_tag="SLE23_002923"
     rRNA            2..>1215
                     /locus_tag="SLE23_002923"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          368 a          242 c          352 g          253 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat actccctagt gaccgatagt
      481 gaaccagtac cgtgagggaa aggtgaaaag caccccggaa ggggagtgaa atagaacctg
      541 aaaccgtgtg cctacaacaa gtcaaagccc gttaatgggt gatggcgtgc cttttgtaga
      601 atgaaccggc gagttacgat tgcatgcgag gttaagttga agagacggag ccgcagcgaa
      661 agcgagtctg aatagggcgt ttgagtatgt agtcgtagac ccgaaaccat gtgatctacc
      721 catgtccagg ttgaaggtgc ggtaaaacgc actggaggac cgaacccacg tacgttgaaa
      781 agtgcgggga tgaggtgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
      841 ctctccgaaa tagctttagg gctagcctcg gaattgagaa tgatggaggt agagcactgt
      901 ttggactagg ggcccatctc gggttaccga attcagataa actccgaatg ccattcattc
      961 atatccggga gtcagactgt gagtgataag atccatagtc gaaagggaaa cagcccagac
     1021 caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg atgtggggtt gcacagacaa
     1081 ctaggatgtt ggcttagaag cagccaccat ttaaagagtg cgtaatagct cactagtcga
     1141 gtgaccctgc gccgaaaatg taccggggct aaacatatta ccgaagctgt ggagtacacc
     1201 tttaggtgta ttggt
//
LOCUS       DARPZJ010000172         1214 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.182, whole genome shotgun sequence.
ACCESSION   DARPZJ010000172 DARPZJ010000000
VERSION     DARPZJ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.182"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            19..1197
                     /locus_tag="SLE23_002924"
     CDS             19..1197
                     /locus_tag="SLE23_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HEI8469734.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAV
                     YQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIE
                     SFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE
                     "
BASE COUNT          445 a          224 c          203 g          342 t
ORIGIN      
        1 agaaaagagg acttccctat gaatgatttt actacagaaa ttgtgcaaac tctagtcact
       61 aaaggcgatt taaatgaatt attccgttcg cacttagaaa aagcgataaa cacactccta
      121 cggactgaat taacggcttt tttagattac gaaaaatatg atcgcactgg ttttaattca
      181 ggtaattcga gaaacggttc ttactttcga tcaatcaaaa ccgaatatgg tgaattaaca
      241 ttggaaatac ctagagatcg taatggtgag tttaaacaac aaactttacc agcctacaaa
      301 agaacaaacg atacattgga aaccactatt atccatttat tcgaaaaagg tgttacgatg
      361 tctgaaattg ctgatttgat cgaaaaaatg tacggtcatc actatactcc acaaaccatg
      421 tccaacatga ctaaagttct gactgaagaa gtaaatgcct ttaaatccag agccttaaat
      481 gataagtatg tcgctatttt tatggacgct acttacattc cactaaaacg tcaaaccgta
      541 tccaaagaag cgatttatat tgccattggt atacgagaag acggcactaa agaagtactg
      601 agttatgcga ttgctccaac tgaatcaaca tacgtttgga atgagctgct acaggatatt
      661 aactccagag gagttcaaga agtcttgctt tttattacgg acggcttaaa aggcatgaaa
      721 gatactatcc atcaaattta tcctaaagca aaatatcagc attgttgtat ccatgtatct
      781 cgtaacatcg ctcataaagt acgtgtcaaa gaccgaaaag aaatctgtga tgactttaag
      841 gctgtttatc aagctaactc aaaagaagaa gcgaatacct tcttatccgg catgattgag
      901 aaatggaaga aaaactatcc taaagtgacg cagtcactca tagaaaacca agacttatta
      961 actttttatg attttccacc tagcattcgt agaaccattt actcaaccaa tctaatcgag
     1021 tctttcaata agcaaattaa aagatacagc cgtagaaaag agcagtttca aaatgaagaa
     1081 tcactagaac gctttctagt cagcattttt gatacataca atcaaaaatt tctaaacaga
     1141 agccataaag gttttcaaca ggtaaccgat acattagttt caatgtttac tgagtaacta
     1201 attattttgc agga
//
LOCUS       DARPZJ010000173         1201 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.183, whole genome shotgun sequence.
ACCESSION   DARPZJ010000173 DARPZJ010000000
VERSION     DARPZJ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.183"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            14..1141
                     /locus_tag="SLE23_002925"
     CDS             14..1141
                     /locus_tag="SLE23_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8469735.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          431 a          211 c          235 g          324 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 t
//
LOCUS       DARPZJ010000174         1193 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.184, whole genome shotgun sequence.
ACCESSION   DARPZJ010000174 DARPZJ010000000
VERSION     DARPZJ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.184"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1076
                     /locus_tag="SLE23_002926"
     CDS             <1..1076
                     /locus_tag="SLE23_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEI8469736.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DARPZJ010000175         1188 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.185, whole genome shotgun sequence.
ACCESSION   DARPZJ010000175 DARPZJ010000000
VERSION     DARPZJ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.185"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            141..398
                     /locus_tag="SLE23_002927"
     CDS             141..398
                     /locus_tag="SLE23_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469737.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="SLE23_002928"
     CDS             complement(630..1061)
                     /locus_tag="SLE23_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEI8469738.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DARPZJ010000176         1179 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.186, whole genome shotgun sequence.
ACCESSION   DARPZJ010000176 DARPZJ010000000
VERSION     DARPZJ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.186"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            70..1026
                     /locus_tag="SLE23_002929"
     CDS             70..1026
                     /locus_tag="SLE23_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469739.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
     gene            complement(1080..>1179)
                     /locus_tag="SLE23_002930"
     CDS             complement(1080..>1179)
                     /locus_tag="SLE23_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8469740.1"
                     /translation="ASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT          417 a          175 c          197 g          390 t
ORIGIN      
        1 ttgacaggga atcctaaaaa cattcggctt tttttatata atctttttaa ctcaacagag
       61 ataagttttg tggaattgta tacgctacct ataattataa aaacagaaaa aatgttaaaa
      121 gatttaaaac agtattatcc tctgtctgct tatgaaaaaa agaaattatt ccacttttta
      181 gcaatcaacc tgttggctga acaagctgat tctttagata ttgctagcaa tcagtcgcta
      241 tttttttcgg atataggatt ttaccactta aaaggagtat taggagaaaa atccgttatt
      301 tttatcaata agacactctc ttggctttat cttcatgata aattggatca aaaatacttg
      361 agaaaaaatg aagatgaaac aatcgaatgg ttgaatgaac gattcattga aagttttgaa
      421 aatcagttta atctgttgcg agaagagacg agccaattga tccgaagaga gttaaccaaa
      481 atacatttta aacttttgca ttacactatt aataaagctg atgaatttcc acttgatgtt
      541 tcttttttta gagaaaacta tccagcattt tattgctatt tgatagagta tataaatgat
      601 ctaacgtcaa aacgcaaaga gttgcttcaa gataaatttt ttcttttttt cagttattta
      661 ttattattga tcaatcacat acccattcaa ctgatttctg aaccagtaaa gatcatcatc
      721 gatttttctt atggtgctgc ctataatcaa tttatcaaga aaaatttaag cttgtacatt
      781 aatctgaaca cggaagtgat agaggcagga aagcctgagt tcccggatgt tataatcacg
      841 aataggaata atctatatga agaaagtgca tctcaagtag tggtttggct cgatccgcca
      901 agagcagtag actgggggaa tcttacaaag attttgttga ctatccaaga agagaaatac
      961 aaagacagca aaattgacaa gcaaatagac gattttcctg aagaaatcat cgacaggatc
     1021 gaatagtgaa cttcttttag aaagtccgac tgctttttct aaaaatatta tttgtcaaat
     1081 taagcgagac aaaactttcc atttacgtaa ctcaaaaaaa cttctaatgg tgtttggtaa
     1141 tttagtgatt ttctagggat atggtttctt ttggacgca
//
LOCUS       DARPZJ010000177         1091 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.187, whole genome shotgun sequence.
ACCESSION   DARPZJ010000177 DARPZJ010000000
VERSION     DARPZJ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.187"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="SLE23_002931"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="SLE23_002931"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEI8469741.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DARPZJ010000178         1009 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.188, whole genome shotgun sequence.
ACCESSION   DARPZJ010000178 DARPZJ010000000
VERSION     DARPZJ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.188"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(128..775)
                     /locus_tag="SLE23_002932"
     CDS             complement(128..775)
                     /locus_tag="SLE23_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HEI8469742.1"
                     /translation="MEQTIKPYQYFFIIREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
BASE COUNT          283 a          193 c          167 g          366 t
ORIGIN      
        1 agaaaggggc tgtccccaga ctttagtagg cgtcattagc tatctttcgt tagcatttaa
       61 aggcgaacac catcacctat tcacttccat taaaagatag catatttttc tgtaaaaaac
      121 aataaaatta tcgttctttc tttacacgtt cagcaaattc atagaaagga gccaatttcg
      181 ttaactgttg attacattgg tcactatcat gacaaatata attccccttt ttcgtatacg
      241 tgccatcaga acctgctttc gttgtagaaa gaaaaagcga aacattcgat gttttctgac
      301 agattgcaca gattccctta tttatcgttg gtgataaagt accgctaatc ccttttaatt
      361 tttcatcttc gtaatagacc atgaattttt tctgcgtacc tggatcattc cagccgatgt
      421 acgtatgttc ttgcaagtcg atttcattcc aagctggttg tttgagtttt ttcacttttc
      481 ggaataattt ctcgatttgt ggtttgctag gctgcataaa cggctgaacg atttgcttca
      541 gctcctccaa tgctctttct gcttgcgctt ttgtcagttt tacgtctaaa actgtcgtta
      601 aaaatgtatc gatttctggc agttcgtgat ctaatatgtc tcgaatcttt tcagctgcta
      661 gtgcctgaac tgtttgtacc gtttttggat cattgacaga tgagtacgca tttaataact
      721 gttctacttc tcttattata aaaaaatatt ggtatggttt tattgtttgt tccatgattt
      781 taaagtcctt tcttctaacc aaagtgcata ctttgtagaa aaaagtgatc ttctgcaaag
      841 tatgtgttac ctgaagatcc tggactcttt taaataagat acgttttgca tcttatcatc
      901 acccccttta atgcttatta ttctatgtac atgattcatt cgataaataa aagtaaaccg
      961 tatcttgaac agatagtcaa ctgcaaacag aaaaaaggac tgtgacaaa
//
LOCUS       DARPZJ010000179         1002 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.189, whole genome shotgun sequence.
ACCESSION   DARPZJ010000179 DARPZJ010000000
VERSION     DARPZJ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.189"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            52..307
                     /locus_tag="SLE23_002933"
                     /pseudo
     CDS             52..307
                     /locus_tag="SLE23_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            371..1002
                     /locus_tag="SLE23_002934"
                     /pseudo
     CDS             371..1002
                     /locus_tag="SLE23_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          344 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaaaa
      301 tataggctct ataatttatg ggactgatga atcaaaattg attcttcagt cccattgtta
      361 ttttaggtat atgattcgta cattgaaaga gttgaaaaac tatcttccga agccgtcaaa
      421 aaggaccctg ccaaaagtat tgatggtgga tgaatttcgt tcgcacgctt caattgtgga
      481 taaaatgagc tttatttgtg cggatggcga gactggaaaa ctcattgata ttttgcctac
      541 acgaaaattg tctcgattaa cacactattt tagtcgctgt gcaaatcctg aagcggtgga
      601 atatttagtg acagatatga acgccgccta cttccaactg acaaaacgtg tcttaccaaa
      661 tgcgaaagtc gtcattgatt gttttcatat catcaaacat ttgaatcagg cgttcaatga
      721 ttttcgtgta caagaaatga aaagattaca ccagttaggg caacgacggg aagccgagaa
      781 agtgaaaaag aactggcgct ttcttctaaa aaaccgtcaa aaaatcaatc actatgatta
      841 caaaacatgg cgcagttttc gtgcacctaa atacccgcta ctcactgaag caatgatgat
      901 tgatcgattg ctggcatttt caacgccttt aaaggacgcc tatacttttt tccatgagct
      961 gaccgaagcc tttagagaca aggaatcaga cttatttttt ac
//
LOCUS       DARPZJ010000180          901 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.190, whole genome shotgun sequence.
ACCESSION   DARPZJ010000180 DARPZJ010000000
VERSION     DARPZJ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.190"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..>901)
                     /locus_tag="SLE23_002935"
     CDS             complement(<1..>901)
                     /locus_tag="SLE23_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HEI8469743.1"
                     /translation="TIFERYQRSEKALIAAMIEMVISGVSTRKVTKTVELLTDGATVS
                     KSFVSNLMKQLDPFVFEWRNRSLEGSEYPFFMCDALYMKVRENHRIVSKGVYIGIGID
                     SDGRRTILGFDVQDGESEDNWDTVFQSFVQRGLFGVKLVISDAHKGLVKAVRKNFLGA
                     SWQRCQAHFLRNIFDKLPKKVSSDVKDELKSIFKASELELTRERKEHFLEKYGCDSKL
                     SAACDILENGFEDAIQILSFPENIRRRIRTTNVLERLNEEIRRRERVIRIFPNINSIT
                     RIIGTLLMEKDTEWLASPRKYLEF"
BASE COUNT          275 a          206 c          148 g          272 t
ORIGIN      
        1 taaattctaa atattttcgt ggagaagcca gccactcagt gtctttttcc atcaaaagtg
       61 ttccaattat ccgagtgatg gaattgatat ttggaaaaat ccgaatcact cgttctctcc
      121 ggcgaatctc ttcgttcaac cgttccaaca cattggttgt acgaatcctt cggcggatat
      181 tttcaggaaa agacaaaatt tgaatagcat cttcaaagcc gttttctaaa atgtcgcaag
      241 cagcacttaa ttttgaatca caaccatatt tttccaagaa gtgctctttt ctttcacgtg
      301 tcaattcaag ttcagaggct ttaaagatac tcttcaactc gtcttttaca tcagaagaaa
      361 ctttctttgg cagcttatca aaaatatttc tcaaaaagtg ggcttggcat ctttgccagc
      421 tcgcacctaa aaagttcttg cgaacagcct taactaaccc tttgtgtgca tcagaaatga
      481 ccagttttac accgaacaaa cctcgttgaa cgaacgattg aaaaacggta tcccaattat
      541 cttccgattc gccgtcttga acatcaaaac caagaatcgt acgtcgtcca tcagaatcaa
      601 tgccgatacc aatatataca ccttttgaga caatacgatg attttccctt actttcatat
      661 acagggcatc acacatgaaa aatggatatt ccgagccttc taggctccgg tttctccact
      721 caaaaacaaa tggatccaac tgtttcatca gatttgaaac gaatgattta gaaacagtcg
      781 caccatccgt tagcagttca actgttttag ttactttgcg agtggagaca ccagaaatga
      841 ccatttcaat catggcagcg atcaaagctt tttcgcttcg ctgatatctt tcaaagatag
      901 t
//
LOCUS       DARPZJ010000181          791 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.191, whole genome shotgun sequence.
ACCESSION   DARPZJ010000181 DARPZJ010000000
VERSION     DARPZJ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.191"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..782
                     /locus_tag="SLE23_002936"
     CDS             <1..782
                     /locus_tag="SLE23_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8469744.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DARPZJ010000182          775 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.192, whole genome shotgun sequence.
ACCESSION   DARPZJ010000182 DARPZJ010000000
VERSION     DARPZJ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.192"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(249..728)
                     /locus_tag="SLE23_002937"
     CDS             complement(249..728)
                     /locus_tag="SLE23_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469745.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          262 a          106 c           87 g          320 t
ORIGIN      
        1 tgacgctccc ttaacaataa atgaagactt ttttattgtt aattgtttat ttttctatta
       61 ttagatatga aaatcgcatt tagataaaat agaaaaatat gaatatattt taaatattaa
      121 gatgagagtc attaacttat gatagtagtc aatttgcttt tcactaatta caaaatatgt
      181 gatataggaa gtttagttat tgttctcata atgccatcct gtttttagat tatctagtaa
      241 tttttttgtt atttaaaatt aggagcagtg ccaattgttt taattttaaa ggcttttttt
      301 atatcttcta aattagaaga tatttgtata tcaatatgga atatattacc ttttttgtat
      361 ttttttatgt tatctttagc taaaacatca aatacatgtc cttgaaattg tatcgaggca
      421 gctggattta gtttaaattg aggaaacttt accacagctg attcaaaaca cttgtcacat
      481 ttttttattt ttttaccttt gtaaaaatat tcgattgaat attctatttg gcacgactca
      541 cttggcagta tatgtatgtc aatatttttc atctgtttca taggtatttc aaaatctaaa
      601 ctattaaaaa catataattc cctgtaatta tttacatcta actctactaa atttatcttt
      661 ggaacaatag atcctccacc cattccacca taataaaaaa aatcttgttc tctatcaaaa
      721 tagcacatat taagctcagt ttgtttatca tcctcaataa ttttataaat caaac
//
LOCUS       DARPZJ010000183          765 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.193, whole genome shotgun sequence.
ACCESSION   DARPZJ010000183 DARPZJ010000000
VERSION     DARPZJ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.193"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            660..>765
                     /locus_tag="SLE23_002938"
     rRNA            660..>765
                     /locus_tag="SLE23_002938"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DARPZJ010000184          734 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.194, whole genome shotgun sequence.
ACCESSION   DARPZJ010000184 DARPZJ010000000
VERSION     DARPZJ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.194"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            220..>734
                     /locus_tag="SLE23_002939"
     CDS             220..>734
                     /locus_tag="SLE23_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEI8469746.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMI"
BASE COUNT          255 a          114 c          162 g          203 t
ORIGIN      
        1 ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt tctaaaagtt
       61 cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt ttgtgagtat
      121 ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa gaacgcatag
      181 gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat taacagagta
      241 acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga aattgcacag
      301 cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga agaagccgga
      361 ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt cctacttccg
      421 ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa atttttaaat
      481 tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa aatcaaatct
      541 attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat taacgtgtac
      601 agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat tcagactgca
      661 atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca agaaccggaa
      721 agcagaatga taga
//
LOCUS       DARPZJ010000185          711 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.195, whole genome shotgun sequence.
ACCESSION   DARPZJ010000185 DARPZJ010000000
VERSION     DARPZJ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.195"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..>711)
                     /locus_tag="SLE23_002940"
     rRNA            complement(<1..>711)
                     /locus_tag="SLE23_002940"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          143 a          230 c          156 g          182 t
ORIGIN      
        1 gtttcaacct tgcggtcgta ctccccaggc ggagtgctta atgcgttagc tgcagcactg
       61 aagggcggaa accctccaac acttagcact catcgtttac ggcgtggact accagggtat
      121 ctaatcctgt ttgctcccca cgctttcgag cctcagcgtc agttacagac cagagagccg
      181 ccttcgccac tggtgttcct ccatatatct acgcatttca ccgctacaca tggaattcca
      241 ctctcctctt ctgcactcaa gtctcccagt ttccaatgac cctccccggt tgagccgggg
      301 gctttcacat cagacttaag aaaccgcctg cgctcgcttt acgcccaata aatccggaca
      361 acgcttgcca cctacgtatt accgcggctg ctggcacgta gttagccgtg gctttctggt
      421 tagataccgt caagggatga acagttactc tcatccttgt tcttctctaa caacagagtt
      481 ttacgatccg aaaaccttct tcactcacgc ggcgttgctc ggtcagactt tcgtccattg
      541 ccgaagattc cctactgctg cctcccgtag gagtttgggc cgtgtctcag tcccaatgtg
      601 gccgatcacc ctctcaggtc ggctatgcat cgtggccttg gtgagccgtt acctcaccaa
      661 ctagctaatg caccgcgggt ccatccatca gcgacacccg aaagcgcctt t
//
LOCUS       DARPZJ010000186          653 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.196, whole genome shotgun sequence.
ACCESSION   DARPZJ010000186 DARPZJ010000000
VERSION     DARPZJ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.196"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..635
                     /locus_tag="SLE23_002941"
     CDS             <1..635
                     /locus_tag="SLE23_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HEI8469747.1"
                     /translation="LSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQ
                     AKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEA
                     NLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFS
                     SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          233 a          117 c          112 g          191 t
ORIGIN      
        1 gcttaagttc aaacttagct tacactatca agattattcg atactttttc atcaagaagc
       61 tcaccaaagg tgaactagtc ggaattatag atagttttcc tagtccatta tgtaaaccag
      121 ttagaaatag acaagcaaaa ctattgaatc aaatagccaa agttggctat aactcaacaa
      181 aaaaatctta tttttatggt cttaaaattc atatgatcgt tactaagact ggctttccga
      241 ttacttactc aatcacgaat ccaggtgtcc atgacgtgaa agtgttagag actttatcgg
      301 aagaagcgaa tcttcccaat atcctagggg acaaaggata tattagccat aaaatccatg
      361 aaaagcttgc ccttaagggc attactatat ccgttccgcc acgtaaaaac atggataaat
      421 cagaaaaact agaccacagc ttacttggaa aacaaagaaa aacagttgag actgtttttt
      481 cttccttaga aaaattaggt tgtcaaaatt tcaactcacg ttctgttaaa gggctagaga
      541 gtagatttga aagcatatta ctggcttaca gtgttctatt aagtcgagca caacgacgtt
      601 ttgaaggaac tttgagatat tctttaggat attaaaatta actagcacca cgg
//
LOCUS       DARPZJ010000187          650 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.197, whole genome shotgun sequence.
ACCESSION   DARPZJ010000187 DARPZJ010000000
VERSION     DARPZJ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.197"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>650
                     /locus_tag="SLE23_002942"
     CDS             <1..>650
                     /locus_tag="SLE23_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEI8469748.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSV"
BASE COUNT          213 a          112 c          134 g          191 t
ORIGIN      
        1 caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag aatatattca
       61 aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat
      121 tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga
      181 cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac
      241 tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg
      301 tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt
      361 tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat
      421 tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac
      481 ttttgattgt ggaaaggaat tttcaaattg gaaacagatc agtaatgtca atgatattgc
      541 catttatttc gctgatccag gaacgccgtc tcaaagaggc ctaaacgaga attctaacgg
      601 attgttacgt agagatggtt tattgaaatc tatggatttc aattcagtag
//
LOCUS       DARPZJ010000188          599 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.198, whole genome shotgun sequence.
ACCESSION   DARPZJ010000188 DARPZJ010000000
VERSION     DARPZJ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.198"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(310..>599)
                     /locus_tag="SLE23_002943"
     CDS             complement(310..>599)
                     /locus_tag="SLE23_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469749.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          207 a           98 c           90 g          204 t
ORIGIN      
        1 attgtgagat gataataaag aagagtttaa agcgcacccc aagccacttc cccataagtg
       61 tgttacgctt taaactcttt tatatttgaa gctattaaaa ggcataccat atttttgaaa
      121 aaaagtgaga aaaaaggctt acaattggag tggtagttaa ttagtgactt atttttgatt
      181 ttatagcact gatactataa aatatagata tcatcatatt acacaatctt aatactaact
      241 taaaaaatat ctcctttcac aagtatggtg ataaaattcg ttccgggcta cctttttagg
      301 tagcctactt taatctttgt atctttctgg atcaacgaaa gtatacttta tatagtcata
      361 acgccgatga tcgctacgtg cgtccggcac gtcagtcacg atatcaaaca aaaagtatac
      421 atccttcttc attctagttt tcgcagcagg aattttgaaa tagttcttat tagaatagta
      481 gagattgatt aataagctat cttcgattgc taaaaagaaa acttctgaat tccatacttt
      541 ataaaaatct ttgataaatc tattcgaagg gtcaaattta aaccataatt gtgtctcat
//
LOCUS       DARPZJ010000189          577 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.199, whole genome shotgun sequence.
ACCESSION   DARPZJ010000189 DARPZJ010000000
VERSION     DARPZJ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.199"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="SLE23_002944"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="SLE23_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEI8469750.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          183 a          123 c           93 g          178 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttg
//
LOCUS       DARPZJ010000190          575 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.200, whole genome shotgun sequence.
ACCESSION   DARPZJ010000190 DARPZJ010000000
VERSION     DARPZJ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.200"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            312..>575
                     /locus_tag="SLE23_002945"
     CDS             312..>575
                     /locus_tag="SLE23_002945"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEI8469751.1"
                     /translation="MSAVVTDLTYVRVGTNWAYICLMIDLFNREIIGHSCGNKKDAQL
                     VKRAIQSIPYSLQEIELFHTDRGKEFDNQTIQNLMNGLVIKFLS"
BASE COUNT          195 a          105 c           82 g          193 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattcc tttcc
//
LOCUS       DARPZJ010000191          546 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.201, whole genome shotgun sequence.
ACCESSION   DARPZJ010000191 DARPZJ010000000
VERSION     DARPZJ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.201"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(271..534)
                     /locus_tag="SLE23_002946"
     CDS             complement(271..534)
                     /locus_tag="SLE23_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEI8469752.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          213 a           97 c           75 g          161 t
ORIGIN      
        1 actctcctga attttttcat gttgaaaaca tcactaatca aaggcaaatt ataatttaga
       61 aatagaatga aaacactaaa tgaaaataga acattagaaa aaatagaatc aaaaaaaccc
      121 aagactagtg ccgaaataag ggaaacaatc gaagctacaa aaaataatga tttcgttgaa
      181 caggaccaat ttatttgttt ccgatatttc tcaaaaagaa ctttctttgg gaaagttaaa
      241 ggcgactgta aagtcgcctt tagtcctttt ttaccaagct gctgcatatt tagctccata
      301 ttttttaatt aatgatttgg ctgtagcaac aataccagct gtaattaatc cgcctccaac
      361 aactgcagca acaatagaaa tgattgtagc aaccgtgcta ccagtattaa ttatgtcaat
      421 aactttttta gctgcataag aagaaattcc aatgttagca cttagcattg gtacaccaac
      481 aaagaatccc gcaaaaccta aaattggtaa aactaataat aaattctttt tcataataat
      541 tcctct
//
LOCUS       DARPZJ010000192          529 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.202, whole genome shotgun sequence.
ACCESSION   DARPZJ010000192 DARPZJ010000000
VERSION     DARPZJ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.202"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(5..90)
                     /locus_tag="SLE23_002947"
     tRNA            complement(5..90)
                     /locus_tag="SLE23_002947"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="SLE23_002948"
     tRNA            complement(107..178)
                     /locus_tag="SLE23_002948"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="SLE23_002949"
     tRNA            complement(190..262)
                     /locus_tag="SLE23_002949"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="SLE23_002950"
     tRNA            complement(280..361)
                     /locus_tag="SLE23_002950"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="SLE23_002951"
     tRNA            complement(369..441)
                     /locus_tag="SLE23_002951"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="SLE23_002952"
     tRNA            complement(445..517)
                     /locus_tag="SLE23_002952"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          136 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactta
//
LOCUS       DARPZJ010000193          509 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.203, whole genome shotgun sequence.
ACCESSION   DARPZJ010000193 DARPZJ010000000
VERSION     DARPZJ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.203"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..132)
                     /locus_tag="SLE23_002953"
     CDS             complement(<1..132)
                     /locus_tag="SLE23_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEI8469753.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DARPZJ010000194          508 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.204, whole genome shotgun sequence.
ACCESSION   DARPZJ010000194 DARPZJ010000000
VERSION     DARPZJ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.204"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>508
                     /locus_tag="SLE23_002954"
     CDS             <1..>508
                     /locus_tag="SLE23_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEI8469754.1"
                     /translation="HMNQAFNELRIREMNELRKVGQKSQAEKLKKNWRFLLKNRANIN
                     HYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHELVEAFRDKDPDLFFS
                     LLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNTHIKTMKRVSYGFK
                     SFENMRIRI"
BASE COUNT          181 a          101 c           97 g          129 t
ORIGIN      
        1 acacatgaat caagccttta atgagttgcg tatccgtgaa atgaatgaac ttcgtaaagt
       61 aggacagaaa agtcaggcag aaaaactgaa aaagaactgg cgctttttgc taaaaaatcg
      121 tgcaaacatc aaccattatg aatacaaaac atggaaaagt tttcgagcac caaaataccc
      181 atttcttacg gaagcgatga tgattgatcg attgcttggc ttttctacgt ccctgaagga
      241 ggcgtatccc tattttcatg aattagttga agcctttcga gacaaagacc ctgacttatt
      301 tttctcctta ttggcagaac ttcccgaaac gttagatgac ggctttcggg aaaagctcca
      361 aaaccttctg acctatgaag aaggcatcac caacgcgatg atctatcctt acaccaatgg
      421 aaaaatagaa gcgaagaata cccatataaa gacaatgaaa cgagtatcct acggatttaa
      481 atcatttgag aacatgagaa ttagaatc
//
LOCUS       DARPZJ010000195          488 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.205, whole genome shotgun sequence.
ACCESSION   DARPZJ010000195 DARPZJ010000000
VERSION     DARPZJ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.205"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..414)
                     /locus_tag="SLE23_002955"
     CDS             complement(<1..414)
                     /locus_tag="SLE23_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469755.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFF"
BASE COUNT          185 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaaacggc tttccaaatg atgaaatacc taaatctaac ttattaagaa agttgaaatt
       61 tttatattca ggaaaccatt tattaatttc atgtgcagca cgtaatgcat tccctggagt
      121 tgtcaaagag aaaattaatt ctgctaagct tattattgaa aatactgata acttataatt
      181 atatcgtcca ttgacaatca aatataaact aactatactt gttagaacaa aaaaacaggc
      241 gttgacttgt tcttgattag ttaaaaatat caataaagga atacttaccc aatatatttt
      301 tctatttatt tcttctcctc ttaagagttg aaaaaacgga taaaaagtta gtaaactaaa
      361 tgctactggc cactgatagt tcaaggtggt tgctctccaa ccggtttccc ccattactgt
      421 caatggtatt aaacagtata tagagcaaac caataataaa tttttaacat ttattttctc
      481 aaaaacat
//
LOCUS       DARPZJ010000196          487 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.206, whole genome shotgun sequence.
ACCESSION   DARPZJ010000196 DARPZJ010000000
VERSION     DARPZJ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.206"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(<1..>487)
                     /locus_tag="SLE23_002956"
     CDS             complement(<1..>487)
                     /locus_tag="SLE23_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HEI8469756.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DARPZJ010000197          460 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.207, whole genome shotgun sequence.
ACCESSION   DARPZJ010000197 DARPZJ010000000
VERSION     DARPZJ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.207"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..>460
                     /locus_tag="SLE23_002957"
     CDS             <1..>460
                     /locus_tag="SLE23_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEI8469757.1"
                     /translation="NMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDFVDLYQR
                     ATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQVENKKLK
                     EENRSLRQRLERLKKAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLF"
BASE COUNT          165 a           62 c          101 g          132 t
ORIGIN      
        1 aatatgctga atgtaaaaaa agagatggcg gtcattttcc aaaaagatat tgttccttta
       61 gaaagtttca agaggcttcc tgatggttcg tatcatttat ctgggaatga ttttgttgat
      121 ttgtatcaac gagctacgag agcaacaaat gccaagagaa atgctgataa catgagtgag
      181 caatatttac agatgcttga gcaaaataca gaattaaatg agtatgtagc tacattggaa
      241 gaagagcgtc atttgtctgg tagaaaacaa ttagcagatt tacaagtgga aaataaaaag
      301 ctgaaagaag aaaatcgctc tttacgccag cgtttagagc gattaaaaaa agcatttcaa
      361 aaatcgatca ctcgtttgtc tatccgtttt ggtcttgcag aaaaggatat ggggctttct
      421 gaggaattag aagtattaga gcaggagaaa accttatttt
//
LOCUS       DARPZJ010000198          450 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.208, whole genome shotgun sequence.
ACCESSION   DARPZJ010000198 DARPZJ010000000
VERSION     DARPZJ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.208"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
BASE COUNT          143 a           90 c           67 g          150 t
ORIGIN      
        1 acactcctct taatatacag tcctattgta taaagtgtta ctatatacat agtaactgta
       61 tacataaaaa aagtcaagta ttagaaaaaa gttcaaaaga tcaagtgtgc gcttcgctcc
      121 cactcccctc gacgttttag tagcctttcc ctcacttcgt tcagtccaag ccaactaaaa
      181 agttttcggg atacattctc cttctcttcc taataatcaa ttaaaatttt aatctttata
      241 tttctgctaa tcactcagga aacagtacag aaaaacaaac acgtatcata gatataaatg
      301 taatggcata gtgcgggttt tattttcagc ctgtatcata gctaaacaaa tcgagttgtg
      361 tgtccgtttt tgggcgttct gctagcttgt ttaaagtctc ttgaatgaat gtatgttcta
      421 agtcaaaaaa ctctgacagc gcctttatat
//
LOCUS       DARPZJ010000199          426 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.denovo.209, whole genome shotgun sequence.
ACCESSION   DARPZJ010000199 DARPZJ010000000
VERSION     DARPZJ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.denovo.209"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
BASE COUNT          151 a           83 c           68 g          124 t
ORIGIN      
        1 ttccgttttt tcatccattc ctttcttccc ccccttacaa ataaataata acctttaaca
       61 accaactcgt aaataggttg gttgttatta tacaaaagga tattagtact cagataaaaa
      121 gttgttagta ctcagataaa aagttgttag tactcagata aaaagttgtt agtactcaga
      181 taaaaagttg ttagtactca gataaaaagt tgttagtacc cttctgtatc cgttgggaga
      241 gtaaggctca actgccccct aaaaagggtt ctaaaaaatc tttaaaaaat aaataaaata
      301 aacgcgcgcg cgcgagcaaa atttcccgcc aaaaaatcac ccacttttta aaataaacag
      361 gttcgcgcat gatattaaac tgccaatcta gctccctatg gtcgctgtaa gaaggagtga
      421 tcgcta
//
LOCUS       DARPZJ010000200        39546 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.022, whole genome shotgun sequence.
ACCESSION   DARPZJ010000200 DARPZJ010000000
VERSION     DARPZJ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.022"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            196..2385
                     /locus_tag="SLE23_002958"
     CDS             196..2385
                     /locus_tag="SLE23_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEI8469758.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2382..4175
                     /locus_tag="SLE23_002959"
     CDS             2382..4175
                     /locus_tag="SLE23_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEI8469759.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            4375..4689
                     /locus_tag="SLE23_002960"
     CDS             4375..4689
                     /locus_tag="SLE23_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8469760.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            4710..5087
                     /locus_tag="SLE23_002961"
     CDS             4710..5087
                     /locus_tag="SLE23_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEI8469761.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            5097..5870
                     /locus_tag="SLE23_002962"
     CDS             5097..5870
                     /locus_tag="SLE23_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469762.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            5892..7295
                     /locus_tag="SLE23_002963"
     CDS             5892..7295
                     /locus_tag="SLE23_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEI8469763.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            7477..8661
                     /locus_tag="SLE23_002964"
     CDS             7477..8661
                     /locus_tag="SLE23_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEI8469764.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            8658..8948
                     /locus_tag="SLE23_002965"
     CDS             8658..8948
                     /locus_tag="SLE23_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469765.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            8945..9166
                     /locus_tag="SLE23_002966"
     CDS             8945..9166
                     /locus_tag="SLE23_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469766.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            9208..9987
                     /locus_tag="SLE23_002967"
     CDS             9208..9987
                     /locus_tag="SLE23_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEI8469767.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            10054..10548
                     /locus_tag="SLE23_002968"
     CDS             10054..10548
                     /locus_tag="SLE23_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEI8469768.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            10604..11242
                     /locus_tag="SLE23_002969"
     CDS             10604..11242
                     /locus_tag="SLE23_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469769.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            11314..11709
                     /locus_tag="SLE23_002970"
     CDS             11314..11709
                     /locus_tag="SLE23_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8469770.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            11693..14146
                     /locus_tag="SLE23_002971"
     CDS             11693..14146
                     /locus_tag="SLE23_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEI8469771.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            14143..16170
                     /locus_tag="SLE23_002972"
     CDS             14143..16170
                     /locus_tag="SLE23_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469772.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            16167..17189
                     /locus_tag="SLE23_002973"
     CDS             16167..17189
                     /locus_tag="SLE23_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEI8469773.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            17206..18135
                     /locus_tag="SLE23_002974"
     CDS             17206..18135
                     /locus_tag="SLE23_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEI8469774.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            18380..18496
                     /locus_tag="SLE23_002975"
     CDS             18380..18496
                     /locus_tag="SLE23_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEI8469775.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            18512..20431
                     /gene="tet(M)"
                     /locus_tag="SLE23_002976"
     CDS             18512..20431
                     /gene="tet(M)"
                     /locus_tag="SLE23_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEI8469776.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            20529..20717
                     /locus_tag="SLE23_002977"
     CDS             20529..20717
                     /locus_tag="SLE23_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEI8469777.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(20775..21128)
                     /locus_tag="SLE23_002978"
     CDS             complement(20775..21128)
                     /locus_tag="SLE23_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8469778.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            21659..22081
                     /locus_tag="SLE23_002979"
     CDS             21659..22081
                     /locus_tag="SLE23_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEI8469779.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            22078..22308
                     /locus_tag="SLE23_002980"
     CDS             22078..22308
                     /locus_tag="SLE23_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8469780.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            22806..23006
                     /locus_tag="SLE23_002981"
     CDS             22806..23006
                     /locus_tag="SLE23_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEI8469781.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            23033..24226
                     /locus_tag="SLE23_002982"
     CDS             23033..24226
                     /locus_tag="SLE23_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEI8469782.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(24294..25859)
                     /gene="guaA"
                     /locus_tag="SLE23_002983"
     CDS             complement(24294..25859)
                     /gene="guaA"
                     /locus_tag="SLE23_002983"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEI8469783.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(25918..26841)
                     /locus_tag="SLE23_002984"
     CDS             complement(25918..26841)
                     /locus_tag="SLE23_002984"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEI8469784.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            27037..27642
                     /locus_tag="SLE23_002985"
     CDS             27037..27642
                     /locus_tag="SLE23_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8469785.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            27950..28966
                     /locus_tag="SLE23_002986"
     CDS             27950..28966
                     /locus_tag="SLE23_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEI8469786.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            29107..30408
                     /locus_tag="SLE23_002987"
     CDS             29107..30408
                     /locus_tag="SLE23_002987"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEI8469787.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            30454..31116
                     /gene="deoC"
                     /locus_tag="SLE23_002988"
     CDS             30454..31116
                     /gene="deoC"
                     /locus_tag="SLE23_002988"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEI8469788.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            31137..31535
                     /locus_tag="SLE23_002989"
     CDS             31137..31535
                     /locus_tag="SLE23_002989"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEI8469789.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            31601..32683
                     /locus_tag="SLE23_002990"
     CDS             31601..32683
                     /locus_tag="SLE23_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HEI8469790.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            32895..34457
                     /locus_tag="SLE23_002991"
     CDS             32895..34457
                     /locus_tag="SLE23_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEI8469791.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            34450..35583
                     /locus_tag="SLE23_002992"
     CDS             34450..35583
                     /locus_tag="SLE23_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469792.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            35583..36539
                     /locus_tag="SLE23_002993"
     CDS             35583..36539
                     /locus_tag="SLE23_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEI8469793.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            36638..37804
                     /gene="deoB"
                     /locus_tag="SLE23_002994"
     CDS             36638..37804
                     /gene="deoB"
                     /locus_tag="SLE23_002994"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEI8469794.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            37828..38646
                     /locus_tag="SLE23_002995"
     CDS             37828..38646
                     /locus_tag="SLE23_002995"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8469795.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            38663..39370
                     /gene="deoD"
                     /locus_tag="SLE23_002996"
     CDS             38663..39370
                     /gene="deoD"
                     /locus_tag="SLE23_002996"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEI8469796.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT        13200 a         6723 c         8056 g        11567 t
ORIGIN      
        1 aaggtttcca acaggccgaa ggcgagctcg aacaaatgct aagccaactg attgagaatt
       61 agaaacaatc tgcagtaggg aagaatcatt tacacaaaat tattgacgct cccttataat
      121 gagaactttt actaacataa tttatgataa acttactata taatcatatt aattaaatag
      181 ttaggagatc tgcttatgtt tatatctact cttcaaattc gaaattttag aaattatgaa
      241 tccgaaatct ttcgattcga taatgagaca aatactatta taggtgagaa tgattcaggg
      301 aaaaccaatg ctcttactgc attgagaatc ttattagatg atagttatta ctatagtagt
      361 aaaacactaa aagaatcaga tttttttcat ggaattcaaa atgggtggca agggcattgg
      421 attattatct ctgcgacatt tgaaggaatc agcgaagaag aatttgacaa tgagatttgt
      481 gcttccattt ctttaaattc tgaaagtcaa acaatcttag aagaattgat ttcaaatgca
      541 gataaaggtg taggtagtat ttctctattt attagaccta acaaagctat tagaaagcaa
      601 ttatttgata tttccactga attagactct catcaattta acgaatttag aaattctatt
      661 cgtctatccg actatgaatt ttactacaca tctaaatcaa atctaaattt ctgtatcaat
      721 gaaaattatg ataaattggt aggaagactc aatgacaata tagctagtaa tcctgaagaa
      781 gacgatgaag ctctgttggg ctcaagaatt gacatgtcag atattttcaa gcatatttcg
      841 gttgtttatg ttgacgctct tcgagatgtt cttagagaaa tgaaaaacaa tcgaaaccca
      901 gtcaaaagaa tcatggaaac aattgaatca aaaatatcat cagataatgt tgagtcatta
      961 aaaacaatta tacagcaatt aaatgagact attaccagtg ttcctgaaat taggaaaatt
     1021 ggcgaaaata ttaatcggca actaaatagc ataattggtt cagtgtattc tcctaatctt
     1081 cttctttcct caactatgtc agatgatatg ggttctttag caaaatttct ttcaatgaag
     1141 ccagaacaaa atatcgactt agacttacta gggttaggac atctaaatat gatttattta
     1201 gctttgaaaa tagtcgaatt tgaagcgtgt cgttcaagag aactacttaa tattatgttg
     1261 attgaagaac cagaagctca tattcatcat catattcaaa aaactctgtt cgaaggatta
     1321 aatcttcaaa aaaactatac tcagattctc atgaccacac attctgtaca tttagctgaa
     1381 gtgtctgaaa tatctcggat gaatgtatta aaatcgttta atggcaaatc tatcgttatg
     1441 aatccagcaa ataatctgaa ctcatttgct aaagaaaagt taaaaaagaa caatctaaat
     1501 ctaataaacg cagtagagag atatttagat gttaaaagaa atggattgct tttttctaaa
     1561 ggtgttatct tagttgaagg agatgctgaa gaaatactta ttcctcaaat agtaaaaaaa
     1621 ttatttggta taaacttaga cgaacttgga ataggtttga ttaatgttgg tagtacttcg
     1681 tttgaatata tcgctagctt gtttgacgat gatagaatac agagaaagtg tgctattgta
     1741 actgatttag atgaacaggc aatcccatca gaacatcgat tgtataaaag cactgcacaa
     1801 gagaaaggtc aagcaagaaa agaaaaatta tcctcccttt ttaatgaaaa caattgggtt
     1861 aattgttttt atgctaatac aacatttgaa attgagtttt tagatgtgaa taaagaaaat
     1921 attctaactt atgtcagtcc aattatagat gacgcattca aagataaaaa aacaataact
     1981 gcttataaag aagaaataca aagtgaacaa tatttagaaa gaaatttagc gatgttaaaa
     2041 ctagccaatc atgttggtaa ggggtggttt gcaattgagt taggtgaaaa aattgacttt
     2101 ttaatcaaaa ttcctaagta tattcttaat gctattgctt ttgcatgtca ggaaatagta
     2161 gatctctcaa tttataaaaa aattctactc catacaatcg acttgtacga ggaaactaca
     2221 gaattgtcag ctttatcagc tagtttaaaa acaagtgata cagctgattt gaatatagca
     2281 ataatttctt tattagagta ctttggtaaa gatgaggatg ttgtgtatct aatcaatcag
     2341 atagaaaatt acacaaaaat actttatgct gaggtttcaa aatgacaaat atcttcgaaa
     2401 aaatcgtaaa tgatttaaat ttagaacaaa aagatgttgt ggaaagtgaa gataaccttt
     2461 atgtaaatgc atgtcctggg agtgggaaaa caagggtact tacaaggaaa attgcttacc
     2521 aagcaattaa acacgatgga tcactaaaaa gaataattgc tatcacatac actaatagag
     2581 ctgctgaaga aattaaggaa cgcctaagtt tacttagtat agatgatgat attaatattt
     2641 gggtggggac aatacatcag ttttgtcttg aatttattat ttatcctttt aaaatgaatc
     2701 tctcaagagt atcaaaagga tttacaatta ttgatgatta tactcaaaga gcttacgtca
     2761 gccaaattaa taatatgctg aatttaaatc tcaaaacgta tgaactgaac aaaattgatt
     2821 tgtcactttc tcatgatttt aaaattaatg aagttcagta tactcaagtt tctgaaatgt
     2881 atcacactat gttggaaaaa aataaagaaa ttgattttga tatgatttta ctagtagcgt
     2941 ataaaatttt aactgtaaac agtaacgttg cacgtaatat tgctagtaat ataagggcga
     3001 tttatgtgga tgaatttcaa gatactagag aattacaata caatgtaata gctaaattac
     3061 ttcaaaacaa ccctcaaatt cagtcaatgt ttgttggaga tattgaccaa gcaatttatg
     3121 gatcattaga tggtatagct aaatcagttg aagaactaga aatgctaact agtcacactt
     3181 ttcaatcaaa gacgctacat ggctgttaca ggtctaatca gagattagta gacttctact
     3241 ctaattttca gagttgtcct tacgagattg aaagcagagg gaataataaa aacgaccgtg
     3301 gttttataag ttatgattgc aaagttacta aggaggattt acccaacata ataaaaaata
     3361 taataaagga aaagattgaa agcggcattc atgaaaaaga tatttgtgta cttgctcctc
     3421 aacactatcc tctgttttca ctgggtgagt atttaaagaa agaattaccg tattgcaatt
     3481 ttgatgctat aaatatatca ccaattaagg taaataatca tagtttattt ttcaagttag
     3541 caattttgta ctttactgaa tcaggtgaaa aggttcgaag aagaaagcta attgcaaacg
     3601 atattttaat tatattaaaa aatgaatttg gaatagaagt taaagattat tttattgact
     3661 tagatttatt acagctaata aacagtgtga aaagaatgta tagtggagac gacaacggtg
     3721 ttgatttata caaatttgtt accaaacata tatttgttaa tcttaatatt gacgagaaaa
     3781 attacccgtc tatttttaag cactatctat tttttattaa cgaagtagaa gatcggataa
     3841 aaaataattc attatctagt agtgtatcta gttttaagaa gatgtttaaa tctcgagatg
     3901 gtatcacact tactacagca cataaagtta aaggaaatga gtatgatact gttatcgcta
     3961 ttaatcttct aaacgggaaa attcctcatt ggaatgaaat ttttaatgtt tctgataaag
     4021 gaattagttc agcgagaaaa ctactatacg taatttgttc aagagcaaaa aataatttat
     4081 ttcttttctc agaggtgggt tattttacga gtaaaggaga cttgctttat cccactcaat
     4141 tattagataa aatagaattt gattataata tttaaaatac ctaggtagtc gttgttttaa
     4201 atatagtagg aatcggacgc tcagtacgga gcgtctattt ttttacccaa ttttgaaagg
     4261 aagtgaactt atgaaaataa aaaatcaaga atcaaaaggt cgctctcccc cctttaaaac
     4321 catcacacaa ataagattca ttcaaacata aaaacagaaa ggataggtaa aaatatggaa
     4381 cttaaatatg tcattcccaa tatggaaaaa acatttggac aattagaata tgctggtgaa
     4441 gggaacattg aacaacgtcg aataaatggc agaccaacca ttctctctcg tagttacaat
     4501 ttatactcaa cgattcaacg agcagatgat attgttgtca ttcttccctc cgaagctggc
     4561 gagaaacatt ttgaatccga cgaaaaagtc aaactcatca acccacatat taccgcagaa
     4621 ggttataaaa ttggcaatcg aggatttacc aattacatta tgcacgcaga cgatatggtg
     4681 aaagcataag aaaggaaagg tgaaaaaata tgagattagc agaaggtatt gtgattgaaa
     4741 aagaccagac atttggcaca ttgaaatttt ccgccttgcg tcgtgaggtt cgtatccaga
     4801 atgaagatgg tacggtttcc gaagaaatta aagaacgtac ctatgactta aaatcaaaag
     4861 gacaaggacg catgatacaa gtcagtatcc ccgcttctgt tcctttgaaa gaatttgact
     4921 acaacgcaga agtggaatta atcaatcctg tggcagatac cgtagcgacg gctacttttc
     4981 gaggggcaga cgttgattgg tacgtgaaag cagacgatct tgtattaaaa ggacagacaa
     5041 aacctcatca gaaatataaa aaagaagcgt ccgaaagtga aaaataggtg ttgcttatga
     5101 caaacacacc attgattttg aaagaaattc cgaaggatga agccatttct tttattcggc
     5161 aataccatta ttcaaagata ctccctagat tgtgtaaata ctttctaggg attttttcag
     5221 aagaaaaatt attaggcgtt gtggaattag gctggggtac gcaaccccta caaaccatac
     5281 gcaaactctt tcccgacagt tcccttcaaa ccacagatta tttagaaatt ggaaagatgt
     5341 gttttcttcc agaaatgaat caaaccaatt attttggcag tcaagctctt tcagctctaa
     5401 ttaagtggtt gaaagaacat acggactgtc attttttata tacactggca gatggaattg
     5461 agggaaaatg tggctatgtc tatcaagcgt ccaacttctt ttactgcggg tatttcaaga
     5521 caagtgtcta tcgtgataag cagtcatggg aaaagataca ccctcgaagt gctcgccttt
     5581 tattagagga aaatgctcgc tttgaacagg tagagaaaaa gcattggctt tcccaggcat
     5641 tttgcgaata caaagggatt gagaaaatca atggacgcat gtttcgctat ctctatccgt
     5701 tgacaaaaga agcgaaaaaa ctgttaggac acactctcta tcgacgtcat tattatccga
     5761 aagaaaaaaa tttacgcttt gaaaagcgaa tcgcttatca gaaatatgaa gccatttctc
     5821 aaccaacttt tgataaacag gctcgtatct acaatacaca attattttga taggtggaaa
     5881 ggaggatttt tatgccattg cttcatgaca gaggagagcg aatcaaagcc aacgataagc
     5941 acttggtcta tcattttgta ctaatttcat tgctggtagt ttttctagtc gtcctactcc
     6001 cttttcattg gagagcgtta caatcggtga actggcaagc agttcagtta gatacatttt
     6061 tctatcaact tcatacgcca tacttttgga gcagtattct cactgctctt tttgtatgcg
     6121 gacttatcag ctggctttat tatcactatc gtatagattc tataaaacag ttagagcacc
     6181 gtcaaaagtt agctcgtatg attttagaaa atcattggta tgaagccgaa gaaactcaat
     6241 cagagggatt ctttaaagat ttacccagca agaaaaccaa acaacgaatc cgccattttc
     6301 ctaaaatata ttatcgaatg aaagatggac taatccatat tcatgtagaa atcaccttag
     6361 ggaaatatca agatcagctt ttgcacctag aaaacaaact agaaacagga ttgtattgtg
     6421 aattagtgga aaaaacgttg aaagattctt atgtagagta tgtcctactt tatgatacta
     6481 ttggcaatcg aattggcatt gaagacgtgg tagctcaaga tggacgtgtc aaattgatgg
     6541 aatcggtcta ttgggagttc gattctctcc ctcacatgtt aattgctggg ggcactggta
     6601 gtggaaaatc ctattttatt ctcacattga ttgaatctct cctgcataca aatgcaaagc
     6661 tttatattct tgaccctaaa aatgctgatt tggcagactt aggggcggtc atgaataatg
     6721 tctattaccg taaagaagat atgttggcat gtatcaatca attttacgaa gatatgattg
     6781 atcgcagtga aaccatgaaa caacacccta actataaaac aggagaaaat tatgcttatc
     6841 ttggtttgtc tgccaatttt cttatttttg atgaatatgt ggcaatgatg gatatgctag
     6901 gtcgtgaaag taccaccgtt attcataaac tcaaacaaat tgtaatgtta ggacgacaag
     6961 caggcttctt tttaattctt gcctgtcaac gtccagacgc aaaatatttt agtgatggga
     7021 ttcgggacaa ctttaacttc cgtgtggctt tgggtcgtat gtctgaaatg ggctttggta
     7081 tgatgttcgg aagcgataca caaaaacaat ttttcttaaa acccatcaag ggaagaggtt
     7141 acgtggatac aggaaaaagt gtgattagtg agttttatac accccttgta ccaaaaaggt
     7201 acgatttctt aggagaaata ggaaaagtca ttcaaaaaaa gcaatctgag cctgtaccgc
     7261 acgaagtgaa aggtacaggt tcagacttgc tttgattggt gtggcgttag ccacgccaat
     7321 cctttagccc cctctatcta acaggggggc acaaatacaa ctgaaaacag gcaattctca
     7381 tcaaccaatg ttgatggtac aaaggattgc ggaaaatatg aaaggtgtaa actcaagggt
     7441 catagtttac atctttttta gattggaggt ttgcgaatgg aaaacgaaaa aatttggatt
     7501 aaggaattga aagaaaagcg actggcttat ggcgtttctc aaaataaact ggcggttgct
     7561 tctcatatta ccagacctta cctatcggat attgaaacag gcaaggcagt ccctactcaa
     7621 caggtgaaag aagatttact gaacgctttg gaacgcttca atcccgataa cccattggag
     7681 atgttattcg actatgtacg gattcgattc cctaccaatg atgtggctca aattatcggt
     7741 gaggttttac gtttgaatat ggattatatg ctacacgaag actttggcta ttattcttat
     7801 cccgaacact atcgtttcgg tgatattgtt gtcctagtct ctcatgatgt aagtaaaggt
     7861 gttttattag aactgaaagg aaaaggctgt cggcaatttg aaaactttct attggctcaa
     7921 catcggagct ggtatgattt ctttcaagat tgcatggaac ataaaggtat tttcaaacgc
     7981 ttggatttag ctatcaacga taaaacaggg attttgaata ttccagattt ggcaaagaaa
     8041 tgtaaacagg aagaatgcat ttccgtcttt cgaagcttta aaaattatcg cagtggtgaa
     8101 ttggttcacc gtgatgaaaa accatacatg ggaaacacac tttatattgg ctcattaaaa
     8161 agtgaagtct atttctgtat atatgagaaa gattatgagc aatacgtgaa aaatgatgtt
     8221 cccttagaag acgcagaagt aaagaatcgg tttgaaattc ggttaaaaaa tgaccgagcc
     8281 acccaagcca tgaaagattt attggcacat caacaggcgg aaaaaacagc ctttgaaatt
     8341 atcaatcgct atatccgctt tgcagataaa gacgacacta aacgtcggag tgattggaaa
     8401 actaatgaac gttgggaatg gtttatcggt aaaaatcgtg gagcattacg cctaaccaca
     8461 cagccagagc cttattcttt tgaacgaaca ttgaactggt tacatcatca agtcgcccct
     8521 acattaaaaa tcgcaagcat tttagatgtt ctcaacggta caaccattat ctccaccatg
     8581 attcaggaag ccaaactgac agaaaaacat gagaaattaa ttgaacaaca acatctagcc
     8641 atggaggatt tgattacatg agccttttaa caaaagaatt aaagaagtta gggtttcagt
     8701 gtggcattga gtttcaagcg tatatacaaa atacagggaa atatacgtct ctcattattg
     8761 agggaaaacg gcaagctggt gataccatct atacctatga tttttacaag gtgagatttt
     8821 ataataatta taccaatcga gtaaccgtct atggagagca tttaacccct tttcaattat
     8881 taaggcgtgt aaaaagctat atctattatc gagaaaaata tcttaaggaa aggaggacaa
     8941 tcacatgaat tttgggcaga atttgtacaa ctggttcttg gataatgcac agtcattggt
     9001 attgttagcg attgttgtca ttggactgtt tttaggtttt aaacgagaat tttcaaaact
     9061 cattggcttc ttgattattg ctctaatcgc cgtcggactt gtgttcaatg cagctggcgt
     9121 gaaagatgtg ttattaaact tatttaaccg aatcattggt gcttaacaga tatttttcat
     9181 gataaaatag gaagtatata ttttgttatg aaaggattta tgaatatgtt tacaaatgat
     9241 caatttaaat ctcttttaat taaaacatta gaaagaaaga gctcttcaaa ttattatgaa
     9301 ggaggtaacg agattgtttc taaaatgaaa atatcagagg taactttaga tgagactgac
     9361 gattttactt attataaagg atataaaaag ggctggaata cgctttgcac atatcttaaa
     9421 ataagagttc cttttgatga tttagacttt tttgaaagtc ataaagattt gattacccag
     9481 acagcaagct ccatatatga taaacaaggt gataatgtat tagtggatac tattttagta
     9541 ccacttccag agaattacga agtaattaac tttagtcagt tgaaaattag tgatgtggtt
     9601 tcacaagcta ttgaagacgc tgagtctttt atgagtaatg gtgaatatca acgtgccttt
     9661 gacagagttc acactgcttt tcatggatat ttaattgaaa tactaaaaaa atatgaaatt
     9721 acagttccta gagacgaaaa tctatctaaa ttatatagta ggatacaaca attaattgaa
     9781 aaagaaattc aacctactga acttgctgat atagtgaaga caacgataag gtcatcaaat
     9841 ggaatgatta gctctcttaa tgaagcaaga aataggcatt cacttgcaca ccctaataca
     9901 aatattattg gaaagagaga agcaaaacta ataataggta tttcaagtac agttacagat
     9961 tatattagcg gataccttga taagtagcgt cattaactga ttgctacttt ttttatgact
    10021 atttttataa aaaggatgtg ataagaattg gaaatgaaag tctatgtggc aaatttagga
    10081 cggtataatg aaggtgaatt agtcggagca tggtttactc caccaattga tgaggaagaa
    10141 atggcagaaa gaatcggttt aaatgaggac tacgaagaat atgcaataca tgattttgag
    10201 cttccttttg atgtggacga atacacgccg attagtgaaa tcaaccgtct atgtgaagcc
    10261 attcaagaaa tcgaaggtac acctatttat aatgaactca aagaaattca aggcatgtgg
    10321 tttagtagct tggaagaatt actggaaaac aaagaggata ttcattgtta tagtgattgt
    10381 gattcgatgg aagatgtcgc ccgttattac gtggaagaaa caggacagct tggtgaagtc
    10441 ccttccaatt tacaaaatta tattgactac caatctttgg gacgtgatat ggaaatagag
    10501 ggtaattacc tagttacctc tcatggggta tttgaatatt gtcagtaagt ttaacaatcc
    10561 gtgttataat taaattaata aatagcacgg agaggtataa attatggtaa atgtatttga
    10621 aaatcttaaa ctattaaaac tagacatgaa agataaaggc tgggtgatag attcctttta
    10681 ctttcgttac aaacagcaaa attatattgt acttgttaag ctatttgaaa aagaggaaaa
    10741 agttccagaa tatgctctgt taaaactaga atttttaaag gaaaacgatt tttcagatat
    10801 gctagctgtc tatgctaatt cggtaaaatt atatacagac acgaaaacaa taagagaata
    10861 ttttggtatc gaatacagta gtaacttggg agatgtttta tttcaattta gccaaactct
    10921 tgctcgattt attccgacag aagttagtga gaagaaaaat gaagaccaaa aagaagccat
    10981 gtgtttctca ttaagtcaaa gtgattcaga agatcccaga aaaaaatatt gtttttcagt
    11041 tagaagaaat cctttaaagg gaaatggtga gctgggaaaa cgaagtcctt ttaatgacaa
    11101 taaaacgaga ttgtatagac ccagcttata tgaacgatta gggtcagata ccaatttaag
    11161 tttcagatat tcaatgaatc cagatgatga agaaactgat gaaggtatta ttgcaaaatg
    11221 gacaaaaaat aaaattgaat agttaaagca ttgaaagagc aatcacctat tttgattgtt
    11281 ctttttctat ttttacggaa aggacgtgaa gacatgaaaa aaataagaag ttacaccagt
    11341 atttggtcag tagaaaaagt gatttatgcg attaatgatt tacaactccc tttcccaatt
    11401 acctttacgc aaatgacatg gtttatcgtt tctttgtttg tcgtcatact ctttggcagt
    11461 ttaccaccac tttctctgat tgacggagca ctactcaaat acttagggat tcccattgtt
    11521 ctcactgggt tcatgtgcca aaagaccttt gacggaaaga aaccctatgg atttctaaag
    11581 tctatcatta cctatgctct acgccctaaa gtaacctacg ctggcaaaca aatacgatta
    11641 aaaaaagaaa caatgaatga atcgattacg attgtaagga gtgaacaact agatggcata
    11701 tccgattaaa tatatggaag ataatctcgt atttaatcat gatggcgaag tattcgctta
    11761 ttatgaatta attccctata attacagttt tttaagttcc gatgaaaaaa ttcaagttca
    11821 tgataatttc tgtcaattga ttgcccaaaa tcgtgatggc aagattcatg ctctgcaact
    11881 agcaaccgaa tcaagtattc gagccacaca ggaacaatcg aaaaaagaaa tcactggacg
    11941 attaaaagag atagcttacg aaaaaataga tgaacagacc gaagcgttaa tttctatgat
    12001 tggtgacaat caagtagact atcgcttttt tattggtttt aaactctacc tcaatgaaca
    12061 ggaagtatcc gtaaaaaatg ttgggaaaga aattcaaaaa gcatttgcgg aattctttca
    12121 tggtgtgaat cacaaattaa tgggcgattt tgtttctatg cctatggcgg aaatcgaacg
    12181 cttttctaag atggaacagt tgttagaaag taaattatcc agacgctttc agattcgtaa
    12241 attggagaaa gatgattttg gttatattat tgaacatctt tacgggcaaa caggtgtccc
    12301 ttttgatgac tacgactacc atttaccgaa acgatacgaa gataaaaaag tgttggtaaa
    12361 gaaatacgat attctcaaac ccactcgctg tttaatcgaa gaaaatcaac gctatttacg
    12421 gattgaacag gaagatacca ctacttatgt ggcgtatttt acaattaata gtattgttgg
    12481 tgaattggat ttccctaata gtgaaatttt ttattaccag caacagcagt ttactttccc
    12541 cgttgatacc agtatgaatg ttgaaattgt cgccaataaa aaagccttat ctaccgttcg
    12601 caataaaaag aaagaactga aagatttaga tagccacgca tgggaaagcg acaacgaaac
    12661 cagtactaat gtggtggacg ctttagaatc tgtcgatgaa ttagaaagta atttagacca
    12721 aaccaaagaa tctatgtaca aactaagcta tgtggtacgg gtatcagcaa agaatttgga
    12781 cgagctgaaa caacgttgtg atgaagtaaa agatttttat gatgatctgt ctatcaaatt
    12841 agtacgacct tttggcgata tgctaggctt gcataatgaa tttattccct caagcaagcg
    12901 atatatcaat gactatattc aatatgtcac gtcggatttt ttggctggtc ttggtttcgg
    12961 tgctacacaa atgattggtg aaaattctgg tatttacgtc ggttacaatc tcgatacagg
    13021 cagaaatatt tatctccaac ctagccttgc aagtcaagga attaaaggct ctgtaacaaa
    13081 tgcattagcg tccgctttta ttggttcatt aggtggcgga aaatcattct ctaacaatat
    13141 gctggtctat tattcagtac tctttggcgg acaggcaacc attgttgacc caaaagctga
    13201 acgtggtgaa tggaaagaaa ccttacctga tattgcccat gaaatcaata ttgttaatct
    13261 cacgagtgag aacgacaata aagggttact tgacccttat gtgattttaa aactcccgaa
    13321 agattcagaa agccttgcca ttgatattct cacgttctta acaggtattt ccagccgaga
    13381 tagcgagaag tttcctgtcc tgcgtaaagc tattcggagt gtaactcaaa gcaaacaacg
    13441 agggttgtta ttggtgattg atgaattgcg aaaagaagat acgcccatca gcaatagtat
    13501 tgctgaccat atcgaaagct ttgtcgatta tgattttgcc catctgttat tcagtgatgg
    13561 cagtgtcacc caatccatta gcttggaaaa acaactcaat attattcaag tggcagattt
    13621 ggtcttaccc gattccaata gctcttttga agaatacact accatggaat tattaagtgt
    13681 ggcaatgctg attgtcatta gtacctttgc tttagacttt atccactctg accgttccat
    13741 ttttaaaatt gttgaccttg atgaggcttg gagtttttta caagtggcac aaggaaaagc
    13801 tctatctatg cgattggttc gagcaggacg tgccatgaat gcaggggtct atttcgttac
    13861 tcaaaacgcg gacgatttac tagatgaaaa gatgaagaat aatattggct tgaaatttgc
    13921 ctttcgttcc actgacctag tggaaatcaa aaagacctta gaattttttg gtgtggacaa
    13981 ggaagatgaa aacaatcaga aacgcttacg tgaattagaa aatggacaat gtttagtttc
    14041 agacatctat ggtcgtgtag gggttatgca gtttcacccg atttttgaag agttgcttca
    14101 tgcctttgat accagaccgc ctgtgcgaaa tgaggtggaa gaatgacaca aaaacaaaag
    14161 aaatttcttc actatagttg gataacgctc ctttgtgtgg gcgttatttt acttttatta
    14221 ggcacgctgg gcaatgcagt acaagcgaca ggcttagttg atgaaaccat tgatacaagc
    14281 aatgaatact ccaagtatgg tttgaatcaa tatcagcttg attattatgt ggacaatagc
    14341 tggggctggc ttccatggaa ttggagtgat ggcataggac aatcggtgat gtatggattg
    14401 tatgccatta ctaattttat ttggacaatt tctctttatc tatcgaacgc cacaggttat
    14461 ttggtgaaag aagcctatgc cttagatttc attagtcaaa catcccaagc aattggcgaa
    14521 aacatgcaga cgattgcagg cattacaccg aatggctttt ccagttcagg gttttatgtc
    14581 ggtttcctcc ttctttttat tctcattgtt ggaatctatg ttgcctatac aggattggtt
    14641 aagcgagaaa cgacgaaagt gatacgagct gttttaaact ttgtcgtggt gtttattcta
    14701 tcggcttcct ttattgcgta tgcacccgat tatattgcga aaatcaatga tttttccaaa
    14761 gatgtcagta ccgccagtct gaatattggg acaaaaattg ttcttcctaa cacggatagt
    14821 caagggaaag acagtgtgga catgatacgt gacagcttat tctctgttca agtaaagcaa
    14881 ccatggctat tgcttcaata tggctccact gatgtagaag cgttagggga agaacgtgtg
    14941 gaaagtttat tgtctaccag tccagataca aacaatggtg aagatagaga aaatgtagtg
    15001 attgaagaaa ttgaagatca tgacaatacc tatttaaccc taccgaagac gatttccaga
    15061 ttaggaacag tcttcttttt gtttgtattc aatattggta tctcgatttt tgttttcctt
    15121 ctaacaggaa tcatgatttt ttcgcaagtg ctatttatta ttttcgctat gtttttgcca
    15181 atcagtttcc tattaagtat gttgccgagt tttgatggca tgggcaggca tgccattacc
    15241 aagttattta atgtgattat gacaagggct ggtattacct tgattattac cgttgccttt
    15301 agtatttcca ctatgcttta ttcgctgtca gcaagttctc cctttttcat gattatgttt
    15361 ttacaaattg tgacctttgc agggatttat tttaaactgg gcgatttaat gagcctattc
    15421 actttacaaa gcaacgactc tcaaaacatg ggcagacaag tgtttcgcag acctcgtcaa
    15481 atgatgaatc gacaaaccag aagatttcaa cgcagtatga gtaagatttt tcgtggaaaa
    15541 gcagggtcaa cgaagcaaaa gacaatgaca acaaagcaga atcaaaccaa taaagctaac
    15601 catactcgtc aaaatgaacg gactacacca aagaaagaaa cagcactttc caatgtgaaa
    15661 aagcaacaag gcggtatcgg gcaacgatta ggtgaaaaga cagcccatgt attggacacg
    15721 aaaaatcgtc tagtcaataa aagaaagcag gcaaaacaac agatacaggc gacaccaacc
    15781 catgtcaaat atgcccttca tcaaggaaaa gagaatgtca ctcataatgt aacagacttt
    15841 aaacaatcta tggcagatac caaagctcaa cgcaaacaac agcgtatgaa ccagcaggag
    15901 caaaaacgaa agaacattgc tcaaaagcgt ttggagctgg ataaagcaaa agaaaaaaga
    15961 cgaaaagaaa acccatcatc tcctgttcag aataaccagc agcatgttcg caagcgtcag
    16021 caaaccgtca cgcctgtttt gtcacaaaac actaaacgtg aaaatcatca gcgaccattg
    16081 aaaaaagagc aaaaacaaaa gacaccaccg aagcaattca atcagaggaa gctaaataaa
    16141 agaacggata agcgaggaca acaaacatga agctaaaaat aacagtgatt tgtagtgtgg
    16201 tcttctctct cttctttttt ctcttattat tcctagtcat tttctttgca gatgatacgg
    16261 acagtggcga aaacaacaag gattcttcta ttccacaagg cggtgtgacc gtttcaccag
    16321 aagtgttggc acaccgtccg ttgattgaaa aatatggtaa ggaatatggg attgaagact
    16381 atgtttctta tatcttagcc attatgcaag tggaatcggg cggtacagca gaagatgtta
    16441 tgcaaagttc cgaatctttg ggtttaccgc ccaacagttt gagtaccgaa gagtccatca
    16501 aacaaggggt taaatatttc agtgaattat taaccagtgc agaacaacaa ggagtggata
    16561 tagattctgt tatccaatct tataattatg gcggtggctt tttaaattat gtgaggagtc
    16621 atgggaaaaa atatacctat gaattagccg aacagttttc taaagagaag tcgggtggtc
    16681 aaaaagcaga ctatcccaat cctatagcca tacctgtgaa tggtggttgg cgatataact
    16741 atggaaatca gttttatgtt cagttggttt cacaatacct aaccgacact tccccaacag
    16801 aatttgatgg tgaaaccgtg caagtcatta tggacgaagc cttgaaatac gaagggtttc
    16861 cctatgtctt tggaggggcg tcgcctacca cctcttttga ttgtagtggc ttaatacaat
    16921 gggtgtatga caaagctggc atttctctcc ctcgtgtcgc ccaagatcag tatgacgcta
    16981 cgcaagaaat ctctatggaa gaagcccaag caggcgacct tatcttcttt cattcaacct
    17041 ataatgcagg cacatatgtg actcatgtgg cgatatattt agagggaaat cgcttttatc
    17101 atgcaggcga cccaatcggt tatggcgact taagcagtcg ttattggcaa gaccatctga
    17161 ttggggctag acgtgttatt cataactaag aaaggaatga atcaaatgat tataaaaatc
    17221 gagcgaaaag aaaagaagga gaaaccaaag aaatctaaaa aaccgagcaa gcaaagaaaa
    17281 gttccgatga ttaaagttgg cacgcataag aaattaacct ttgttttatg ggttttattg
    17341 attggtagtg tcggatttgg aatctataaa aattttactg ccattgacac tcatactgtc
    17401 cgtgaaacag aaatcattaa acagcagatt gtcgatacca accaagtaga aagttttgtg
    17461 aaatcctttg cgaaagacta cttttcgtgg caacaatccc aagaagccat tgataaacga
    17521 aatgaaaaat tgacccatta tttgacggaa gaattgcagg tattaaatga agaaatgatt
    17581 cgtaaggata ttcctactag ttctagtgtg aacgatatac aggtgtggca ggtttctcaa
    17641 gtgaatgaga acacctttga ggtactgttt tctgttgaac aagttattac cgaagacaaa
    17701 gacaaggaaa ctatatcgtc tagctttcat gtggttgtcc atatagatga atcagataat
    17761 atggttatta tcaaaaatcc gacaatgagt aagaaacctc aaaaatcgga ctaccaaccc
    17821 aaacagctag aaagtgacca tacagtagat acagaaacga tggacgaaat cactagcttt
    17881 ttagaaacgt tcttccagct ctatcctacc gccacagaaa aagaattgac ttactatgta
    17941 agtaatcatg tgttacctat gattaacaag gaatatgttt tcgaggaatt ggtgaatcct
    18001 atctttacca gaaaagataa ccaagtaatc gtgaatgtcg ctgtgaaata tttagatcaa
    18061 gaaacaaagg caacccaaat ctcgcaattt gagttgatat tagaaaaaca agataattgg
    18121 aagattgtaa aataacaaat attggtacat gattacagat actttgtaat catgtactct
    18181 ttttgataaa aaattggaga ttcctttaca aatatgctct tacgtgctat tatttaagtg
    18241 actatttaaa aggagttaat aaatatgcgg caaggtattc ttaaataaac tgtcaatttg
    18301 atagcgggaa caaataatta gatgtccttt tttaggaggg cttagttttt tgtacccagt
    18361 ttaagaatac ctttatcatg tgattctaaa gtatccagag aatatctgta tgctttgtat
    18421 acctatggtt atgcataaaa atcccagtga taaaagtatt tatcactggg atttttatgc
    18481 ccttttgggt ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc
    18541 tcatgttgat gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat
    18601 tacagaatta ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg
    18661 tcagagagga attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt
    18721 gaacatcata gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc
    18781 agttttagat ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg
    18841 tatattattt catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat
    18901 tgaccaaaat ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc
    18961 cgaaattgta atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac
    19021 cgaatctgaa caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat
    19081 gtccggtaaa tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa
    19141 ttgttctctg ttccctcttt atcatggaag tgcaaaaagt aatataggga ttgataacct
    19201 tatagaagtt attactaata aattttattc atcaacacat cgaggtccgt ctgaactttg
    19261 cggaaatgtt ttcaaaattg aatatacaaa aaaaagacaa cgtcttgcat atatacgcct
    19321 ttatagtgga gtactacatt tacgagattc ggttagagta tcagaaaaag aaaaaataaa
    19381 agttacagaa atgtatactt caataaatgg tgaattatgt aagattgata gagcttattc
    19441 tggagaaatt gttattttgc aaaatgagtt tttgaagtta aatagtgttc ttggagatac
    19501 aaaactattg ccacagagaa aaaagattga aaatccgcac cctctactac aaacaactgt
    19561 tgaaccgagt aaacctgaac agagagaaat gttgcttgat gcccttttgg aaatctcaga
    19621 tagtgatccg cttctacgat attacgtgga ttctacgaca catgaaatta tactttcttt
    19681 cttagggaaa gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga
    19741 gatagaacta aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata
    19801 taccattcac atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc
    19861 accgcttccg ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa
    19921 tcaatcattt caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata
    19981 tggttggaat gtgacggatt gtaaaatctg ttttaagtac ggtttatact atagccctgt
    20041 tagtactcca gcagattttc ggatgcttac tcctattgta ctggagcaag cctttagaaa
    20101 agctggaaca gaattgttag agccatatct tagttttaaa gtttatgcac cacaggaata
    20161 tctttcacgg gcatataacg atgctcccaa atattgtgca aatatcgtaa atactcaact
    20221 gaaaaataat gaggtcatta ttattggaga aattcctgct cgatgtattc aagattatcg
    20281 caatgattta acttttttta caaatgggct tagtgtttgt ttagcagagc taaaaggata
    20341 tcaggttacc actggcgaac ctgtttgcca gacccgtcgt ctaaatagtc ggatagataa
    20401 agtaagatat atgttcaata aaataactta gtgcgtttta tgttgttata taaatatggt
    20461 ttcttattaa ataagatgaa atattcttta atatagattt gaattaaagt ggaaaggagg
    20521 agattgttat tataaactac aagtggatat tgtgtcctat ttgtggaaat aaaacaagac
    20581 tacgaatacg agtggatact atacttaaaa atttcccttt atactgcccc aaatgtaaga
    20641 acgaaacttt aattaatgtt caaaaaatga atataataac aatcaaagag ccagacgcca
    20701 agacgcagag ccgataattt gagaaatgaa actctcatct tatcggctct ttttgtttat
    20761 ctgaatttta ctgactagcc ttcaatattt cttgcttcat tgataccttt tgctagtgct
    20821 tccattaagg atagttcttt gtctgtaaag ctatccatgt atttttctac ctgtaacctt
    20881 cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt catcaataga tacatggagt
    20941 aatgatacaa gatcatacag cacttgtgta cttgggtgtt gtcctttgtt ttctatattt
    21001 gttaaataac gtgggtcaat ttcaatcatt gttcccactt gttcacgagt gagaccccgt
    21061 ttcattcgag cctctttaat cgctaaacca acggctctaa aatcgtattt atcttctttt
    21121 ttacgcatac taaatcacct ctatacattt tactgttcct atataaccat aaacaggtat
    21181 agaaaaacat gttatatagt ttatgagttc ctatagaaca ctgtggaatt tattaatgcg
    21241 atgaatccaa tttcaaatag aaaggtcgct gattttattt acctatacaa ctttataaaa
    21301 tttagtcata ctcctagaaa gtagataaaa ttggcgactt aatggaggga aaagtcgcca
    21361 tgagaaagat aatctgtcat ctagttctct taattaagtt cttatcaaaa aaacttatcc
    21421 acctgtactg gatagatatg accatcaatg tggttttgca gattacatag atagaaaaat
    21481 caaagcatat gaacagagaa aacaatctgt ttatgtgctt ttttggtcac ttaataaata
    21541 tcttttagga tttctcttca tttatgcaac aaatccccct ttcgtgtcgg ggtttagtat
    21601 gaagggagat aaagaagcac atgccactcc ctttcacgac agaaaggggg tgaaaagcat
    21661 gaaaccatct tcttttcaag aaaccataga aaatcagttt gactatatct gcaaacaagt
    21721 tattgaagat gaacgaaaag attacttcaa acatctagac agactatcag caaaagaagt
    21781 ctcgttttct gatatagata actaccttgt caactctttt tctactgttg atacgtacgt
    21841 cactgatttc caactattta aattatttgg attaagaatc aatgttgaaa gtgatttatt
    21901 aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac attattttac ttcattactt
    21961 tatggatatg agtgatgtgg agattgcgga gttactaaat ttgaatcgtt cgactgttta
    22021 tcgtcatcga ataagtggac tagccatgat taaagaattc atgaaggagt gtaaagaatg
    22081 aaaacagctt atccaagggt tcccttcccc ctcattgtaa aggcgacaga tggcgacgtg
    22141 gaagcaatta atcagattgt taaacattat cgagggtata cctcaaaacg ttcattacgt
    22201 cgcatgacag acgaatatgg aaattctcat atggttattg atgaaaccct acgtggcaga
    22261 atggaaacga aactcatctc taagatttta tcgttcgaaa ttaaatagtc ccattttttc
    22321 gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg gaggtttgtt attccatcaa
    22381 agcatattgt gtgttcagta ggttttgata ggctaacaag ccaaacgttc tttgacaacc
    22441 aaataaaggc aatcgaatac gtttcggtaa gaaaagagct gatgaactaa cacgccatga
    22501 cctacaaaat tagtgagcga ttcatgttag taattcgaaa gtaatcttta gcaggattgc
    22561 tgccatgact ttcttatcgt gataatgata ctcccgtata gccatagtcc gagcgttaga
    22621 agcgtcacag gcaatgggta cggctacatg agaaccatgc agaagtgaaa ttcctgtgag
    22681 ctttgctaga gctgttcgat tgctaagata ttcttctctt gtcagtgtat tattataaaa
    22741 ctatttgata taattatagg tgaatattgg agttttccta gcctataatt gggaaaggag
    22801 taataatgat aacggtcaca aaaaaggatt tagttgagct aggatatgga acttcttttt
    22861 cagcagacat cataaaaaaa gcaaaagaat tgatgattac aaaagggcat atctactatc
    22921 aatctcgaaa gctagataga gtccctcgtg aagctgttga agaaattcta ggaattcggt
    22981 tttcaaatga aaacaggtct gagtagtttt tgcacagtaa ggagtaaaaa ctatggttaa
    23041 agacccaata aaaaaagcaa agaatggaac ctattatttt cgtgcaaatc taggttatga
    23101 ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc actactaaaa aagaagcaag
    23161 agaagaatat tcgaaactgc tattgatgaa accagaagaa ttaagtgaga ataaggataa
    23221 aatgacgttt aaacattata tctttgaaat tttccttcca tggtataaga cacaggtaaa
    23281 gctcagaaca tatgaaaatc gcttaccaac tattaagaag catttctctt attttgataa
    23341 aatggctgtt tccgatattg agcctattga tgtgcaaaat tggcaactaa aattatcaaa
    23401 gaagtgtaag tcttcttatg taagagctgt tcaaggacta ttttcagttg ctatggatcg
    23461 agcaattgtc cttgggataa ccaccacaaa tccatctaag attattggca atgtgaaaaa
    23521 gcaaaagtct aaaattgaat tttggacaaa agaagaattt gaaaaagtaa tctctctaat
    23581 ttacaaagaa gattactatc aacacttttt atttatctct ctgtggtttt tatttatgac
    23641 tggaatgcga attggtgaag ctactgccat tcaatgggaa gatattgatt ttgactcagg
    23701 agtactaacc atcaacaaaa cactctatta caagaatcaa tcgaattata gatttgttga
    23761 accaaaaaca aaggcgagcg ttcgtcatat tgtattagat aaatgcacat taacttattt
    23821 atccgaatgg aaggaagtac aacaaaatct aattcagaca gactttgtaa tgagctataa
    23881 cggtattcct acccaaaaac atacactatc atatgctatt gaacgctatg ctaagctggc
    23941 tggtatccat cgaatcagaa tccatgggtt acggcattct catgcttcct tgttaatcag
    24001 tatgggagaa aatccactta tcattaaaga tcgtctagga cacgaagata ttgagacgac
    24061 tttaggaacg tatggacatc tttatcctaa cagtaatttc gaggtagcta acaaattaaa
    24121 tggagccatt tcctttaaag aagcaaaaca aaattatgat acttcaccaa agaatcaatt
    24181 tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg caataaaagt gcagtaaaaa
    24241 gataagaaga gccagaaacc cttggtataa gaggatttct agctctccta caactattcc
    24301 cactccactg ttgctggtgg tttagaagtg atgtcataca cgatacggtt gacgtgggct
    24361 acttcgttta cgatacgtac agagattttt tgcaagactt cccatgggat acgggcaaag
    24421 tcagcggtca ttccgtcgat tgaagttaca gcacggatac cgactgtgta gtcgtaagta
    24481 cgtccgtcac ccataacacc gacagagcgg atccctggaa gaacagtgaa atattgccag
    24541 atatcacggt caagtccagc agctgcgatt tcttcacgca agatagcatc agattcgcgt
    24601 acgatttcta gcttgtcttc agtgatttcg ccaagaacac gaataccaag accaggacca
    24661 gggaatggct gacgccaaac gattgaatca ggcatgccta actgagtccc taattcacgg
    24721 acttcgtctt tgaataatgt gtttaatggt tcgatcaatt caaattgcat atcttctggc
    24781 agtccaccta cattatggtg agatttgatc gtctgtgctg tttctgtacc agattcgata
    24841 acgtcagtat acaacgttcc ttgtgctagg aaagagacgc cttcttcacc agcaagtttt
    24901 gttgcttcgt catcaaaaac atatacgaat tcattcccaa tgattttacg tttttgttct
    24961 gggtcagata cacctttcaa cttgtctaag aagcgatctc ttgcatcgac tttgatgatg
    25021 ttcaagccga attttccgcc tagactttcc attacttgtt ccgcttcgcc tttgcgtagc
    25081 agaccgtggt caacaaagat agatgtcaat tggtcaccga tcgctttttg taaaagaacc
    25141 ccaacgacac tagaatcaac gccacctgaa agaccaagca agactttttt gtcaccaact
    25201 tgttcacgga ttttttctac ttgcatatcg ataaagttat ccattgtcca gttaccttca
    25261 cagtgacaaa catcaaaggc aaagtggcgc agcaattcga ttccgtattc ggaatgacgt
    25321 acttctgcat ggaattggat accataaaaa ttacgtgttg tgtcttggat agaagcaatc
    25381 ggacaatctt tgcttgttcc gactgtttca aagccttcag gaactttagt taccaagtca
    25441 ccatggctca tccatactgt ttgttgtttt ggtgtttctt taaacaagac agcttgatcg
    25501 cttgttactt ctaacaaggc tttcccatat tcgcggtttt tagcaggctc tacggaaccg
    25561 ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc ctaatacagg aatacctaaa
    25621 ttgaagatct caggatcgat cccaaatgca ttctcatcat atacactgtt tggtccgcca
    25681 gaaagaatga ttccctttgg attcatcgct tttacttctt ctgcagtaat gcggtggctc
    25741 aataattcgg aaaagactcc aagatcacga atacgtcttg tgatcaattg gttatactga
    25801 ctaccgtagt ctaatacgat aatcttttca acgttcgtca tatcggcaac gtttgtcaaa
    25861 tttattaccc ctatcccttt aaattttatc tcaaaatagt caaactattt taaaatgcta
    25921 atattttcgc atgaaaatcg aatcgatgat atgattttca gttttatgga gaattatatc
    25981 ggctcttcct cgtgtaggca agatatattc ctgtaaattt ttcaaattca catttttcca
    26041 tacatctttt gccattttaa aggcttcttc acgatctccg atagcaaaac gataataata
    26101 attctctgga ttttggaaag ccgtatccag taacgcacca aaacgatcca aataccattt
    26161 ttcgatcagc acgggatcgg catcgacata gacagaaaaa tcaaaaaagt cgctgacgta
    26221 gatttgctga ttcgcaggta attgaagcgt attgatcccc tcaacgatca agatatcagg
    26281 ctgctggatc aattcgtact tgtctggaat gatatcatac acatcatgtg agtaaacagg
    26341 tacttttatc tcttcctgac cagattttac acggttcaag aaatcgatca gcatctccat
    26401 atcataactt tcaggaaatc ctttacggtc catgattcca cgctctttta atatacgatt
    26461 tggataaaga aatccgtcag tcgtgatcag ctgaacgttt cttcgtttga aggtacgaga
    26521 caaaatcgtc tgcagcagtc tggctgttgt actttttcca acggctacac ttccggcgat
    26581 cccgataata aaaggcggta cttctacgta tttatgaaga aataaacctt tactcaagaa
    26641 caaagattca aattctttca tataaagata aatcagatga gcaagaggta catagatatc
    26701 tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg atattatcta gttcatcttg
    26761 tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat tcttctcttg ccacacggta
    26821 gtagttcatt ggatcattca tattagcctc ctgcgttctc ccatcaatgg aactatttta
    26881 acacaaaata aacgcaaacc ccaccactta agagagattg ccgatctttt tgtataatct
    26941 ttataataga aagaaacgga gtcttattct tgacttgcgc acggatacat aaaaggatag
    27001 actgttgtca tgaaagaaat gagaaggatg gaagacatga caaatcatta ctattctgaa
    27061 cgcccagata cggcgcacga ttttgaacaa tgggcttttg agttaaaagg cagaaccttt
    27121 caatttgtaa cagattctgg tgtattttca cgtgaaacag tggattatgg ttcacgtgtc
    27181 ctgattgatg ctttcgattg ggaagagtta cctgatgaag gaaagatctt agatgtggga
    27241 tgcgggtatg gaccgattgg gttagctttg gcatttgcga cacagcggtt tgttgaaatg
    27301 gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa acgcaaagcg taaccaaatc
    27361 gaacatgttg atatccatca atcgaatatc tatgaagcag ttcatgaaga aacctatgca
    27421 gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag ttgtacatga aattttgaca
    27481 ggcgcatatc ctcggttgaa gaagggcggt acactgacaa ttgtgatcca gaagaaacaa
    27541 ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg gtaatgcaga aatcgtcaca
    27601 aaagataaag gatattatat catcaaaagt gtgaaagaat aactagctga aaaatagtgg
    27661 agcgacgaaa gagtggaact gggcgtgcat gtacgggtac gtatcagttc tttttttgtt
    27721 gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa agaaatagta ggaacagagt
    27781 cgttgttttt tacgataaaa taaataagat acagaacttg tatagaaggc tgccaagtcg
    27841 gtagataaag gaggttttta tcaaaaaaca tactttcctt ttttctctat tcttttcttg
    27901 ggggttttgg tacactgata gggaatttag atagaaggga gccaatagga tgaagctgac
    27961 catcagagat atcgcagaaa tggcaggcgt atcagtaaca actgtctcac agattttgaa
    28021 taacaaagga agcagattta gtgataagac aagaaaaaaa gtgttgtcga tcgtgaatga
    28081 acatcattat aagcccgatt atttcgcttc aaatgtgatc aatcgacatt caaagaccat
    28141 cggaatgatc gtccctgatg tcactgattt cttcttctcc aaactgatcg aaggtgtaga
    28201 gagctatttg aatcctttgg gctatgtgat catgttatgc aattctcgtc atagccaaga
    28261 aaatgagatc aagtatttac aagagctttc ccaccgctca gtggacggaa tcttgctggc
    28321 cacaccaaat attttacctg agaaatatgc attagacagc ggtttttatc aaaaaatgcc
    28381 aatcatttta atcgatcgcg gattgaatcg tcgggataac ggacggctta tcgtaaagga
    28441 atatgagggc gcctatcaag ctgtttcgct gtttattgaa aatggccata cgaagatcgg
    28501 catgctgaag gaaaccactg gatactatca attagaagaa cgtttcaacg gatatcgtca
    28561 tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt gttgaacatg gagagttgac
    28621 tgtccaaggt ggatatactg catcaaaaaa attactcaaa cataaagata tcacggctat
    28681 tttttgcggg aatgatgcca tggcgatcgg atgctatcag gcgatcgatg aattgggcaa
    28741 aaaaatccca gaagatatct cagtcatagg attcgatgga ttaaagctgt cagaatacat
    28801 gattccgcaa ttgacgacag tgcagcagcc aagttttgat attggatttt atgctgcacg
    28861 tttcctgatc gatacgatcg aatttcctca aagaaaagtt ccgaacaaag tgttcgaaac
    28921 aaaattaatt attcgtgaga gcgtaaaagt attgacaaag ggctaactcg gcggtatatt
    28981 gcttatgtaa gcatttacaa aggctagtta gtgctttttt tatttttagt aaaccagttt
    29041 actaaagtgg tttacctttc ctaaaaataa tgtataatac cgaatgaaga caaggaggat
    29101 caggcaatgc gaatggtgga tctgattgaa aaaaagaggg atggaaacga gctgtcgaaa
    29161 gaggaaatcg agtacatcgt cacgaactat acgaatggaa agattccaga ttatcaagtc
    29221 agtgcattat tgatggcaat tttttatcaa gacatgacaa atgaagaaat cacgaactta
    29281 acattggcga ttgctaattc tggtgatgtc atcgatttga gttctcttga aggaataaag
    29341 gtagataagc attcgacagg tggcgttggt gacacgacca cattgatttt agccccccta
    29401 gtagctagtg tcggagtgac agtggctaaa atgtctggac gcggtctagg ttacacaggt
    29461 ggtacactag acaagctaga agcaattccc ggatttcaga tcgagctttc ggatgaagaa
    29521 tttgtacgca ttgttaatga aagtaaagta gcggtaattg gtcaatcagg aaacttggca
    29581 ccggcggaca aaaaattgta tgccttgcgt gacgtcacag cgaccgttga ttctcttccg
    29641 ctgattgcca gttcgattat gagtaaaaaa atcgcggcag gagcagatgc aatcgttttg
    29701 gatgtgacca ctggagacgg tgctttcatg aagaacatcg aagatgcaag acgtctggca
    29761 aagaccatga cgagcattgg gaaactggct aaccgagaaa cagtggcggt tatctcagat
    29821 atgtcagaac ctcttggcga agctatcgga aatagtctag aagttgtcga ggcaatcgaa
    29881 acattacaag gaaatggtcc agaagatcta gtagaaatgt gctacgcctt aggaagccaa
    29941 atggttgttc ttgctggcaa agctaagaca accgatgaag caagaacgtt gcttcaagaa
    30001 gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa tgatccaaaa tcaaggggga
    30061 gacccagcga tcgtggaaca tccagaacga attttgactg cacgctacac aatggagctt
    30121 cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa atgaattagg aattgctgca
    30181 atgatgctag gtgctgggcg taaaaccaaa gaagaagata ttgatcacgc tgttggattg
    30241 aaactgcata aaaaaattgg tgacactgtg acaaaaggtg agtcactatt gacgatctat
    30301 agtaacgacg aagaaatcac ttctgtcatt gaattattat ataaaaatat tgaaattggt
    30361 gaatcggcaa tgaagccaac gttgattcat gacatcatca cagaataaag gaaaaaagcg
    30421 gactttaccg ttttaaagaa aaggggaaaa gaaatggaac taaaccgaat gatcgaccat
    30481 actattttga aagcagacgc atctaaagaa gctgtgatgc aaattatcga agaagcaaaa
    30541 aaataccatt tttattctgt ctgcatcaat ccagcatggg ttgcgctagc gaaagaacaa
    30601 ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt ttcctctagg agcaaacaca
    30661 cccgagacaa aagcatttga aacaacagat gccatcaata acggtgcaga tgaagtcgat
    30721 atggtcatca atatcggtgc tttgaaatca aaggatgatc aacaagtcca aaaagatatc
    30781 gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca aagttattat tgaaacatcg
    30841 ttattagata gagaagaaat catccgagct tgcgaaatag caaaagctgc aggcgctgat
    30901 tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa aggtagagga tgtccgtttg
    30961 atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt ccggcggtat ccataacgaa
    31021 gaagaagcaa tggcaatgat cgaagctggt gctacaagaa tcggaacaag cgcaggagta
    31081 gcaatcgtat ctggttcaac tggtgaaggc tattaatttt ttcaaaggag aagctcatgg
    31141 cagaactcaa acaagaatgg atcaacacag ctattgaagc gttagataaa gcctatgttc
    31201 cttattccca ttttccggta ggcgcttgtc tcgtaacgga atcaggcaag atttatcaag
    31261 gcatcaacat tgagaatgca tcatttggat taacgaattg tgccgagcgc acagcttttt
    31321 tcaaagcagt atctgaagga gaaaaaacat ttacgcatct agtcgtagcg gggcacaccc
    31381 ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat ggcagaattc tgttcccctg
    31441 atatgccggt tacgctagta ggagacaatg gtgtgacgaa ggcaacgacc gttcgtgcac
    31501 tgctgcctta tgcatttact gaaaaagatc tataactcat gttcattcag tcagctgact
    31561 gttgaaaaat aaaacaatta ttttaggagg ctttacagaa atgaaaaaag caaaattatt
    31621 tggtttaggt gctgtcgcac tagcagcagg gttattttta ggtgcatgcg gcaacaacgg
    31681 ctctactgat tcatccggtg gcaaaagctc atcagacaca acaactgcag cattgatcac
    31741 agacacaggt ggtgtagacg accgttcatt caaccagtca gcttgggaag gactagaaaa
    31801 atgggggaaa gatcaaggac tttcacgagg aaatgatggc ttccaatatt tccaatcttc
    31861 aaatgaatca gattacatcc caaatattga ccaagcattg aatgctggat tcaaaacgat
    31921 ttttggtatt ggttataaac taaaaccagc gatccaagaa caagcaacaa acaatacagg
    31981 tacgaacttt gttattatcg atgatgtcat cgatggatta gataacgttg tatctgcaac
    32041 tttcaaagac aacgaagctt cttatcttgc aggtgttgca gcagcttata cgactgaaac
    32101 aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta atcgatcgtt ttgatgctgg
    32161 attcaaagcc ggtgttgatg caggtgcgaa agaattagga aaagaaatca aagtattgaa
    32221 tcaatatgct ggtgacttct ctgctccaga taaaggacgt tcaattgctc aaggtatgta
    32281 tgcacaaaac gcagatatca tcttccatgc ttcaggcggt acaggtaacg gtgtattcca
    32341 agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt tgggttatcg gtgttgaccg
    32401 cgaccaatca gacgaaggcg aatacacatt aaacggcgaa aagaaaaact tcacattgac
    32461 atctacactg aaagcagttg gaacagtagt agaagatttg gcacaaaaat cagcggacgg
    32521 taaattccct ggcggcgaac acactgttta tggattgaaa gaagacggtg ttggtctaac
    32581 agaaggacaa ctttctgacg aagcgaaaaa agcagttgat gaagcaaaag aaaaaatcat
    32641 ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac taaaaccatt tctatagcct
    32701 tgttagacac atgtttgaca aggctatggt ttgattagaa caagaattgt tcatttatcc
    32761 aagctgcctt gtgacagttt ggataaggga acaactccct gaagtaatgt ttgtttcaaa
    32821 agaagaacgc tcactaagcg tgaatcttag tcaatcgttg ccctagatag aaatcgttag
    32881 gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga aatgcagaat attaccaaag
    32941 aatttggaac attcaaggca aatgacaaca tcaatttaca agtaaaggca ggagaaattc
    33001 atgcgttgct tggagaaaac ggtgctggca aatctacatt gatgaacgtg ctttccggat
    33061 tattagagcc gacatcaggg aaaattttga tgcgtgggaa agaagtaaag atcacaagtc
    33121 cgaccaaagc caaccaatta gggattggga tggtccatca gcactttatg cttgttgatg
    33181 cctttactgt aacagaaaac atcgtgttgg gaagcgagcc tagtcgcgca gggatgcttg
    33241 accataaaaa agcacgaaaa gagatccaaa aagtttctga acagtatgga ttgtcagtca
    33301 acccagatgc ttacgttcgt gatatttcag ttggaatgga acaacgggta gaaattttaa
    33361 aaacacttta ccgaggagca gatgtactga tttttgatga gccgacagct gtattgaccc
    33421 ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt agtcaaagaa ggcaagtcga
    33481 tcattttgat tacgcataag ttagatgaaa tcaaagcagt agctgaccgc tgtacagtta
    33541 tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga cgtaacctca caacaattag
    33601 ccgatatgat ggttggaaga acggtttcat tcaaaacgat gaaaaaagaa gcgaagcctc
    33661 aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga aaatcgtgga ttagaagccg
    33721 tgaaaaactt gaacttagag gttcgtgctg gcgaagtact tggtatcgct ggaatcgatg
    33781 gaaacgggca gtcggagttg atccaagctt tgactggttt gcgaaaggca gaaagcggac
    33841 atatcaagct aaaaggggaa gacatcacta ataaaaaacc ccgaaaaatc actgaacatg
    33901 gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt agtcctagat atgacattat
    33961 ctgaaaatat cgcactacaa acctatcatc aaaaacctta cagtaaaaac ggcatgctga
    34021 attattcagt aatgaatgaa catgccagag aattgatcga agaatatgat gttcgaacaa
    34081 cgaatgaact tgttcccgca aaagctttat caggcggaaa tcagcaaaaa gcaattatcg
    34141 ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc aaatccaact cgtggactgg
    34201 atgtaggtgc gatcgaattt attcataaac gtctgatcga acaaagggac aaatacaaag
    34261 cagtgttact gatcagtttc gaattagaag aaattttaaa tgtttcggat cgtattgctg
    34321 ttatccatga aggagaaatt gtcggtatcg ttgatccgaa agaaacatct gaaaatgaat
    34381 taggtctatt gatggcgggc tataccttag aagaagcacg aaaagagtta gaaaaggggg
    34441 ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt tattagtgcc tgtactttca
    34501 gttgttttag gattgatctt aggcgcgata ttgatggctg cttttggttt tcagcccatc
    34561 caaggttatt cttctatgct agatgcagcc cttggttcgc aaagagggat aggtgaaacg
    34621 ttaaggcaag caacgccgtt gatttttaca gcattaggtt tttctgtagc taactcagct
    34681 gggtttttca atattgggct ttctggacaa gcactttgcg ggtggatcgt cagtgtctgg
    34741 gtggcacttg cgtttccaga tctgccaaaa gttgttttgc ttccgttatg cgtgatctta
    34801 ggtgccttag ctggtgcgat ggcagcggct gttccaggtt tacttcgagc attttttgga
    34861 acaagtgaag tgatcgtaac aatcatgatg aactatatct tattatacgt aagcacattt
    34921 gctttacatg aagtgatgcc tgaaagctat cgctcaagtt tggactcttc caatatgatc
    34981 agtcaaaatg cctcactgcg gttaccatgg ttaacacaag cttttggcgg ctctcgcgta
    35041 aactcaggat tatttttagc aatcatcgcg cttattttcg tttggctgct gatgaagaaa
    35101 acgactttag gatttgaaat ccgttctgtt ggattgaatc cttttgcttc tgagtatgca
    35161 ggaatgagta gtaaacgtac gatcgttttg tcgatggtca tttctggcgc tttggcaggg
    35221 cttggcggtg tggttgaagg attaggaacg tatcaaaact tctttgttca aacgacttcg
    35281 ctatctattg gatttgacgg aatggctgtt tccttgcttg gttctggatc agcaatcggt
    35341 attcttttat cagcgatctt gttcagtatt ttgaagatcg gtggacttgg catgcagaca
    35401 ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg ctttgattat cttctttgtc
    35461 gggatcaact tcctgattcg tttcgtcatg gctaaagtct tccaagggaa aaaacaagaa
    35521 gagatcgttg cgacaataga atcgaaacca acgaatcaaa accatgaagg gggcgaacta
    35581 taatgtcgac tatcgaatta attgccttga tccttacttc tacactggtt tattcaacac
    35641 cgctaattct aacgtcacta ggcggaactt tttctgaacg aagcgggatc gtaaacgtag
    35701 ggctagaggg aatcatggtc atgggtgctt ttagttccat cgttttcaac ttgacgatga
    35761 gtccatcact tggttctatg acaccatgga tcgctatttt agtgggtggc gtcgtaggta
    35821 tcctattttc tctgattcac gcagtagcaa cagtcagttt gcgtgctgac catattatca
    35881 gcgggacagt aattaatctg atggcacctg ctttaggtgt tttcttgatc aaagcatggt
    35941 atggtaaagg tcaaactgat aacatcacgc agaatctggg gtatttttct ttcccaggat
    36001 tagcagatat tccggtcatt ggaccaattt tctttaaaaa tacattctta cctgcttatt
    36061 gtgctatttt gattgctgtc ctagcttggg tgatcatctt caagacgaaa ttcggcttgc
    36121 gcctccgttc agttggtgaa aatcctcaag ctgccgacac attaggtatc aatgtatatg
    36181 ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg cggtatgggc ggtgctgttt
    36241 ttgctcagtc gatttccggt aacttttcag ctggtacgat cgttggacaa gggttcatct
    36301 ccatggctgc tatgatcttt ggtaagtgga atcctttagg ggcaatgggt gcctcattgt
    36361 tctttggttt tgctcaaagc ttgagtatca ttggcgcaca attaccagtt atttcttcga
    36421 ttccgccagt attgctgcaa attgctccat atttgctgac aatcattgtg ctggttgttt
    36481 tcttagggaa agcttctggt ccaaaagcaa acgggaagaa ctatatcaaa tcaaaataat
    36541 cttttagcga ataaaaaggg tgggttacgg gaagtgtttt tcgtctcgcc ctttttgttt
    36601 taaaggcaat aaaaataaaa agaaagaagg aataatcatg tttaaacgcg tacatctgat
    36661 cgtcatggat tcagtaggaa ttggagaagc accagatgcc gataagttcg gtgatgttgg
    36721 ttctgataca ttaggacaca ttgcgaaaga agcaggattg aacgttccac atttagagca
    36781 gcttggttta ggaacgatcc gtcctcttga aggtgtggaa tcagtgaaag atcatcaagg
    36841 ctatgcgacg aaattagaag aagtttctgt agggaaagat acgatgacag gccactggga
    36901 aatcatggga ttgaatatca aaactccatt tcgtgtgttt cctaatggat tccctgatga
    36961 tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc gtatgtaaca aaccttatag
    37021 cggaacagct gttattgacg attacggtga acaccaaatg aaaacaggcg atttaattgt
    37081 atatacttct gccgatcctg tccttcagat cgcggcacat gaagaaatca ttcctttaga
    37141 agaattatat cggatttgcc aattcgttcg tgatataaca aaagatgatc cgtatatgat
    37201 tggccgaatc attgcacgtc cgtacgtggg tgaaccagga gacttcacac gaacaagcaa
    37261 tcgccatgat tatgcgttga atccattcgg acacacagtc cttgattctt tgaaagaagc
    37321 aggaaaggac gtgattgctg ttggaaagat caacgatatt ttcaacggac aaggaatcac
    37381 tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac cagctgctga aagttatgaa
    37441 aaacgatttt tcaggaatca gctttaccaa tttagtagat tttgatgcat tatacggtca
    37501 tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa tttgacttac gaattccaga
    37561 attgcttgaa gcgatggaag aagacgactt gctaatgatt acagccgatc acggaaacga
    37621 tccgacgttt actggtaccg atcatacgcg agaatatgta ccgttattgg tttacagtaa
    37681 aaaaatgaaa gaacaagggg cattgcctca aggatattat tcagatattt cagcaacgat
    37741 tgctgagaac tttagtgttt cttcgactga aaatggcgaa agcttcttga aattattaaa
    37801 ataatctttt taaataggag aaagcaaatg accaagttaa gcgagatgtt acaagaaacg
    37861 acccagttta tccttgataa aggagtaaaa gaaattgatt ttggtttgat tctaggttca
    37921 ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa tgatttctta tgatgagatc
    37981 ccgttctttc ctgtttcgac agtagttggg catgcaggaa agctagttta tgggtctctg
    38041 gcaggcaaga aagtgttagc catgcaaggg agattccact actatgaagg tcattccatg
    38101 caaacagtga cctatccagt acgtgtgatg gccggactag gggcccattc agtcattgtg
    38161 actaatgcat gtggtggtgt caacgaatca tttgtaccag gagatttgat gctgattacc
    38221 gatcatatca attttactgg tgaaaatcct ttgatcggtc cgaatgaaga tgcaatgggc
    38281 cctagatttc cagatatgag tcaagcttat acgcctgact atcaagcaac agcaaaagca
    38341 gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat atatgggcta ttctggacca
    38401 acttatgaaa cgcctgcgga gatccgaatg tctcggacaa taggagccga tgcagtaggg
    38461 atgtcgactg ttccagaagt catcgtagca gctcacagcg gattaaaagt gttaggaatc
    38521 tcttgtatta ccaacttagc agcaggtatg caagcgaatc tgagccatga agaagttgta
    38581 gaaacaactc agagagtcaa acaatctttt aaagcattgg ttaaagaaac attgacatta
    38641 ttgtaatagg aggaacaata aaatgagtgt gcatattgaa gcgaaagaag gcgagatcgc
    38701 cgataagatt ttacttccgg gagatccttt gcgagctaaa tatattgcgg agactttttt
    38761 ggaagatcca gtttgttaca atcaggtacg cggtatgtta ggctttaccg gcaaatataa
    38821 aggagaacgt atttctgttc aaggaacagg aatgggaatg ccatcagcca ccatctatgc
    38881 ccatgaattg atccagtcgt atggtgtaaa gaaattgatt cgagtaggta catgcggtgc
    38941 attgtcaaaa gacgtccatg ttcgtgattt agtactagca caaggtgcag cgaccagttc
    39001 ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct ccaatcagtg atttcaatct
    39061 attactgaaa gcatatgaga tagctaaaga aaagggctat acggttcatg taggaaatgt
    39121 tctttcggaa gattctttct acaaagatga tttgacagag acgttccaat tagctgaact
    39181 tggcgtttta ggagtggaaa tggaagcagc ggctctttat tacttaggcg cgaaatacca
    39241 tgtgcagaca ttaagtttga tgaccgttag cgaccatttg atcaccggtg aagaaacaac
    39301 agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa gtaggattgg aaacagcgat
    39361 agcagaataa gaaggaaatg aaaaagctgc cctgcattaa gtaataagaa catccaagca
    39421 aaaatagctc ctcatgtttt tgacttggct ggacttatta ttgcaaatgt aagcttttga
    39481 acaccgttta ccaagaggtt gtgaatctgc cgtttaactc tgagtcacaa ggaacaattt
    39541 caaaaa
//
LOCUS       DARPZJ010000201        20985 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.043, whole genome shotgun sequence.
ACCESSION   DARPZJ010000201 DARPZJ010000000
VERSION     DARPZJ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.043"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(134..577)
                     /locus_tag="SLE23_002997"
     CDS             complement(134..577)
                     /locus_tag="SLE23_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEI8469797.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="SLE23_002998"
     CDS             complement(795..2135)
                     /locus_tag="SLE23_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8469798.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="SLE23_002999"
     CDS             2404..3300
                     /locus_tag="SLE23_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEI8469799.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="SLE23_003000"
     CDS             complement(3450..4391)
                     /locus_tag="SLE23_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEI8469800.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="SLE23_003001"
     CDS             4517..5638
                     /locus_tag="SLE23_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEI8469801.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="SLE23_003002"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="SLE23_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEI8469802.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="SLE23_003003"
     CDS             7426..7992
                     /locus_tag="SLE23_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEI8469803.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="SLE23_003004"
     CDS             8203..9264
                     /locus_tag="SLE23_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEI8469804.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="SLE23_003005"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="SLE23_003005"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEI8469805.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="SLE23_003006"
     CDS             10177..12159
                     /locus_tag="SLE23_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEI8469806.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="SLE23_003007"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="SLE23_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEI8469807.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="SLE23_003008"
     CDS             12881..14305
                     /locus_tag="SLE23_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEI8469808.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="SLE23_003009"
     CDS             complement(14486..15259)
                     /locus_tag="SLE23_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEI8469809.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="SLE23_003010"
     CDS             complement(15256..16161)
                     /locus_tag="SLE23_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEI8469810.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="SLE23_003011"
     CDS             complement(16315..16635)
                     /locus_tag="SLE23_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEI8469811.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="SLE23_003012"
     CDS             17109..17795
                     /locus_tag="SLE23_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEI8469812.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="SLE23_003013"
     CDS             17797..18741
                     /locus_tag="SLE23_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEI8469813.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="SLE23_003014"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="SLE23_003014"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEI8469814.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="SLE23_003015"
     CDS             19663..20940
                     /locus_tag="SLE23_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469815.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6778 a         3784 c         4362 g         6061 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcgt tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcacta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaatagagg ctgggacaga agcgtttaac tccaagaaat aagaa
//
LOCUS       DARPZJ010000202        16775 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.053, whole genome shotgun sequence.
ACCESSION   DARPZJ010000202 DARPZJ010000000
VERSION     DARPZJ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.053"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            366..1229
                     /locus_tag="SLE23_003016"
     CDS             366..1229
                     /locus_tag="SLE23_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEI8469816.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1329..1811
                     /locus_tag="SLE23_003017"
     CDS             1329..1811
                     /locus_tag="SLE23_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEI8469817.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(2074..2541)
                     /locus_tag="SLE23_003018"
     CDS             complement(2074..2541)
                     /locus_tag="SLE23_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEI8469818.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            2664..3515
                     /locus_tag="SLE23_003019"
     CDS             2664..3515
                     /locus_tag="SLE23_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8469819.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(3766..5724)
                     /locus_tag="SLE23_003020"
     CDS             complement(3766..5724)
                     /locus_tag="SLE23_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEI8469820.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(5721..6593)
                     /locus_tag="SLE23_003021"
     CDS             complement(5721..6593)
                     /locus_tag="SLE23_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEI8469821.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(6935..7807)
                     /locus_tag="SLE23_003022"
     CDS             complement(6935..7807)
                     /locus_tag="SLE23_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEI8469822.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            7935..8504
                     /locus_tag="SLE23_003023"
     CDS             7935..8504
                     /locus_tag="SLE23_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEI8469823.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8571..9308
                     /locus_tag="SLE23_003024"
     CDS             8571..9308
                     /locus_tag="SLE23_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEI8469824.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            9539..10807
                     /locus_tag="SLE23_003025"
     CDS             9539..10807
                     /locus_tag="SLE23_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEI8469825.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            11294..11758
                     /locus_tag="SLE23_003026"
     CDS             11294..11758
                     /locus_tag="SLE23_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEI8469826.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            11742..12371
                     /locus_tag="SLE23_003027"
     CDS             11742..12371
                     /locus_tag="SLE23_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEI8469827.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            12725..14203
                     /gene="msr(C)"
                     /locus_tag="SLE23_003028"
     CDS             12725..14203
                     /gene="msr(C)"
                     /locus_tag="SLE23_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEI8469828.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            14250..14696
                     /locus_tag="SLE23_003029"
     CDS             14250..14696
                     /locus_tag="SLE23_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEI8469829.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(14895..15410)
                     /locus_tag="SLE23_003030"
     CDS             complement(14895..15410)
                     /locus_tag="SLE23_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEI8469830.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            15527..16729
                     /locus_tag="SLE23_003031"
     CDS             15527..16729
                     /locus_tag="SLE23_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEI8469831.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         5300 a         2989 c         3482 g         5004 t
ORIGIN      
        1 gatgaggttg aacttttaca caagattgtg gacttgactg caaagaaaaa tccaagcagc
       61 gttctgatca gcagtttgaa caacaatttg ctttgtacag taggtagtaa gcggattaac
      121 taagggaata aaagatattt ttaccgcttt gtttacttag aatctgtctt ccccaaaatt
      181 tatttttcta aaggtaaaac atagataggc agataatacc aattatccgt tacgaaacgc
      241 tgcttgagaa ttttctttag atccatacaa cattttctac atctgactaa attggttcct
      301 gattcatcaa gtaattgact ttctttgata atatgataaa aaggcaatca aggaggaaga
      361 taaatatgct taaagatctg aaccaattga tcgattacat cgaagaacat ttgacagaag
      421 gactttccta taaaataata gccgaaaata caggaatctc tgaatatcaa ttaaaacgca
      481 tctttacgtt tattgcaggg atgtcgctaa tggactatat caaaaaccgt agattggctt
      541 tggctaatcg cgatcttcta gatggatcaa gagtgacaga aacggcgttt agatatggat
      601 atgaaacagt cgaaggtttt tcaagagctt ttcgtgattg gtcaggatat ctgccttcag
      661 aaatcagcag atacggcata caaaaatctt ttccacgctt gacatttttt attgatgtca
      721 gaggaggaaa atcgatggaa tttcgtatcg aaaagaaaga acagttttat gtggcaggtg
      781 tggcgaaaaa agttcctgtc aaatttgaag gagtcaatca agaaatacaa aagttagcgc
      841 agacgatcac ggagactcaa agggaagaga tgcataagtt aggagattta tatccaaatc
      901 aagtaatcaa cgtttcttat ggatttgatg gagaccgctt ggaagaaaag ggcagtttga
      961 tgcacatgat tggctttgct acgacaaaag aaaatccgta cgctgattta gaaatgcttg
     1021 ctatagaaga acacacttgg gccatttttc ctaataaagg gccatttccc caaactttac
     1081 aagatacttg ggggaaaatc tatgcagaat ggcttccttc ttcagattat gggttagtcg
     1141 aagctcccga gatctctttt acaaaatggg gagaggattt cagtaatgtt tacagtgaga
     1201 tttggattgc agtgaaagca aaaaaatagt taaaaaataa aaatatccct agaaaaaaga
     1261 gcgtaatcgt gtcatttccc tttaatttta tgtaagatga acttaatata atagaaaggg
     1321 tgggagaaat ggcaaagtat aggatcgaag aaaaaccaga ttttacggtg acgggtattg
     1381 gtgtggaatt gaagagtagc aatacggatt ttgtcggttt ggctgcagag aaacaagcat
     1441 ttgagcaaaa agttatcggt aatggaacaa tagatgcatt gaaacaagct gctgaaaatc
     1501 attatttctt tacagtcaac gaaccctata acgggaaaat gatgtactat gtcggtgttc
     1561 aaacgagtca ggatgttcca aacactacgc gaatcatccc attcccaaaa ggaacgtatc
     1621 ttgttgtaag cgctttagca gaatcgcctg aagaattaag aaatgatttg acgaatacgg
     1681 cctttgggca tgttttaaga gaagtagaag attacgccta tgttgggggt ccaaatgctg
     1741 tagtcgaaat gggagttacc aacgggaaat atatgggaga aatctggata ccggtagtca
     1801 ataaaccatg ataatataga ggtcgtgaaa gtagcgcttt gacctgagca ttagagagga
     1861 aaaatgggaa atagctttcc atattttgca tttttcagaa ctaatgccga gggtcagcta
     1921 cttgaacacc gtttatcaag acgtcatgac ttcagcgctt tgacctgagc attagagagg
     1981 aaaaaggggc atgacaaggc ttttgtcccc cggagaataa aagaatttat gtagacgatt
     2041 ccgatcagaa aaatgcaggc acagtagaga gaattataaa aatctctcta cgaggcctgt
     2101 gttttctggt cttttttctt tttccaaaac ggctatttta tgtatcagac tatcaagtgt
     2161 gatcttagcc atttcttctt ctgccttttt ctgcagccga gcgtagcttt cttctaaagc
     2221 ttcttggata ttcgcaccaa cgacgcaatt tggatttgtt tttggatcga cttggataag
     2281 ctgtgtatta ccttcgatgc tgcgatagac atctagtaaa gaaatctgat ctggactttt
     2341 ggcaagggaa ggctgcggtt ttccggtttt tgtaaagatc aaaccggatt ttttgagctg
     2401 actcatgatt ttacgtacat ttgctgcatt tgtttcgata ctactggcaa tcatctcact
     2461 agaaagtgat cgggtatctt gaaacatttc aatataggca agtacatgga ttgcatcact
     2521 aaattgcaga gaatacttca tcagttgtca tcctttcatt ttttttgctt gacttatctt
     2581 accacactct ttatgataaa ggtgtaattt ataaatgtac agctgtaaat cttaacaaat
     2641 aaaaagaata gggagtggca aatatgcatt atttagtaac aggagcaact ggaggttttg
     2701 gtggttatgc gctggaattc ttaaaaaaga tggttccaca aaatgaaatc tatgtactag
     2761 tacgtagtga agaaaaagga gaagcactga aagaagctgg atttaatata cgtattggtg
     2821 attatgatga tttagactca atgaaagaag cgttgaaagg aatagatcga ttgctttttg
     2881 tctctggcgt tccaggaaat cgtcaagccg aacataagaa tgtagtgaag gcagcacaag
     2941 cagctggggt atcttatatc gcttatacaa gttttgcaga tgccgatcac tcgatcagtg
     3001 tattagcgcc agatcaccaa ttcactgaaa aaatgattaa ggattcaggt atttcccata
     3061 catttttacg gaataattgg tatgtagaga atgaattacc tatcattggg caggctttaa
     3121 aaactggtca attcgtttat gctgcaggaa atggaaaaac aggttgggca ttgaaacgtg
     3181 aatatgcaga agctgcagca aaagtactag tagaaagtga ctctccagaa atcttagaat
     3241 tatccggcaa tctaactgac tatgaagaat tagccaaggc attagagcgt gcgacaggta
     3301 aagagttaga aattattgaa gcaagtgatg cagcgtttgt cgaaaatcta aaagaagccg
     3361 gattccctca agaagcagct gacatgtttt tagcgatcca acatgatatt aaaaaggatc
     3421 agttagctat ttcctctgat gatttagaaa aagtattggg aaaaccatta acttctcttg
     3481 aagcagcatt aaaagaaata ttggatcagg aataatgtat aaagaggttg tgaaaaagcc
     3541 gattagtttt gagtatgaag aaaaattttg tgaaaaagct gttctgcatc aagtaataag
     3601 aagagtcaaa taaaaaatag ctcttcatat gtttcgttta gctggactta ttaccgcgga
     3661 gttggcagga gaacgccgtt tttattcgga aaaaggagct gagacaagat ttttgtctca
     3721 gctcctgttt gtttatcgat aaaaaagtct ggggaagacg atggctcagg ctttgttgga
     3781 aacagagccg attttatcat ttgcttttac atcacgtgcg ggttcgattt ctaagctttg
     3841 gactttgtcg ccatttgtga atacaacgac catatccgtg tttttgcctg cagattgaat
     3901 agcggcaaga tcaactaaag caatcaattg acctcttgcg actttttgac cttcttctac
     3961 atataaagtg aatggttcgc cttttaagtc aacagtgttg atgcccatat gaagcaagac
     4021 ttcgatacca gcatctgttt ggattccgac agcatgtttc gttgggaaaa tgtttgtgat
     4081 cgtaccagcg attggagaga agatttctcc attttctggt aatacagcat agccgtcacc
     4141 catcattttt tccgcgaata catcatctga aacttcagtg attggaatca gtttcccatt
     4201 tgcgatagcg taaatatctt gttcgatcgt ttcaccggca aatgtttctg ttttaaccac
     4261 ggtgtttgtt tgtgcaggtc gtgctgcagc accaccatgt agttttgcca tctcatctgc
     4321 aacgaattgt acttctgtac ctacgatgac ttgcgcattt tttccgtcga tgatcttcat
     4381 accaggtacg ccagtggctt tgattttatt ttgatcgatc aggcctgtat ctttgacttg
     4441 caaacgaagg cgtgtagtac agttatcgat cgaagttaca ttgtcggctc cgcctaatgc
     4501 agcgtagatt ttgcttgctt gtgccgcata tttattgtct gaattagtcg ttgcagtatc
     4561 gtcatctgaa agatctgctt cctcgcggcc aggagtcatc agatggaatt ttttgatagc
     4621 aaagttaaag ccaaagtagt aaatcactgc tgttactaat ccttggacga tcaacatcaa
     4681 tggctgattc gcaatcggat ttttcaaaga taggaagtaa tcgacaaatc cggcactaaa
     4741 ggcaaatcct gctgtccaat ggaagaatgc actcactgct aaagaaatcc cagtgaaaat
     4801 tgcatgcaag acatataatg gccaagcaac gaacataaat gaaaattcaa gtggttctgt
     4861 cacaccagta aagaatgaag caaaagctgc tgctagcatc aaggaagctg tttttgcttt
     4921 gttttctgga cgtgcatttc tgtaaatagc atatgctcct gctggaagcc cgaacatcat
     4981 gattgggaaa aatccagctt gatacattcc tgttacgcct tttgttcctt cagaagccaa
     5041 aaatttacca atatcattga ttcctgctac gtcaaaccag aacacggagt tcattgcttg
     5101 atgcaatcct gtagggatca gtaaacggtt gaagaagcca taaagacctg caccacccca
     5161 gcctaaactc aaaatgaatt tagcaaaaga aactaaagca gagtaaaccg gaggccatac
     5221 gagcagtagc actgcactga tcagcaacat gacaaaggca gccaagattg gcactagacg
     5281 cttgccgcta aagaaagata aagccatcgg taattttgct tcgtggaaac gattataaag
     5341 agctgccgca atcaatccgg caataatacc aataaatacg ttactgatct gagcaaaaga
     5401 tggatcaact gattctggtt tgatattcaa taaagtagct actgaatcag tttttaaaac
     5461 atttactgga acttcaaatg cgaccaaacc tgccaaggca gcagcacctg atttgtccac
     5521 tgacatccct agtgctaacc caacggcaaa cagcaaaggt aattgaccta aaactgcgtt
     5581 accgccagct tgtaaaaaat gagcgacaat gtcgttacta taagatgccc accagtttcc
     5641 gatccctact agtaaagcag cagcaggtaa gaccgcaact ggaagttgaa gggaacgtcc
     5701 cattcgttgt agatatgctt tcaatttttt tcctcctcat gattgttaac atttgtttgt
     5761 acgattgcgc ttcttaaacg ctcgatatgg atggccaagt aacccagttc ttctttcgtg
     5821 atcgcgagct ggtattcttt ggtcagcaac acacggattt ttttagaaat cttatagctt
     5881 tctgggtatt ttcgtttgac catttctacg atttccgtgt ctaaaacagc atattgttgc
     5941 gcatgggttc gttgtagaag tagtcgtaaa tgattcacca gtcttgaata attcagtgaa
     6001 aatggttctg aatggatatc tgtttccaat tctgattcca ctaaatggat gatgtcagat
     6061 acaatcgtca cttcacggat actgcgatgg ttattgttcc gaccgcttcg tccgctgtga
     6121 atatggattg cgatatatcc tgcttcgtca taagtatatg gaatcccaag ctcttttgtc
     6181 agatactcta ctgcccattg agcaatactg aattcatcac tgtaaagcac ttcgatttct
     6241 cttaaaagtt tgttgcggat gacgataccg ttattaatgt tctccgcaga aaaagcaatg
     6301 tggtcggtca aagcgatcaa tacatgttca ttcaactttt ccatcaaaac agtttccgca
     6361 tgatcaatga tcgtttctgc tgcaaataaa aagcgttcat caatctgatt aagtaaattt
     6421 tgcaacttga tttgaccttc tggttccatg acaaatatcc gttcgacatc acgatcaaaa
     6481 atcaaatcat ttctttttct gtcaaatcca atcccttttc caatagctac tttttcctgt
     6541 ccaccgtcat ctaccaatac tgcattttga ttaaagatct ttttgatttt catgcgcgca
     6601 ccctttttga agatttggtt ttcacgtttg ctagaccagt tgattgcggc caaacaaaaa
     6661 tagacacgaa aaacctccta gggaaaccat gttcctcaga gatttttcat gcctagtatg
     6721 atctagtcac atgaaacgaa ttattgttaa cgtaatcaat tttatataga cagttatgtt
     6781 ttgtcaattc tttttttata attatagtaa tttactggaa ttatcagaaa taaaaggaag
     6841 aaataaatta agaaacttat gttatttaat cgttggatct tttgcttatc ttattcgttg
     6901 ttaaaaagct gaaagcgaag gaaaaaaact ctacttaact gtatttctcc gttaggacat
     6961 ctaaaaattt acgagcagca ggagaaagag gctggtcttt tttccaaatg agattcagtg
     7021 aagcttgtaa tggcggatcg agtgggatga atattttttc cgtcccataa gtattgatga
     7081 tcccatctag agctaatgca ccaaaagtcc cgttatcgac catcaaagaa gcattgtaca
     7141 ataagttata tgttccgacg atcgataact gatctatgct gaaacctagc cattcagcta
     7201 gttgactgtc cactgacgtt tgccgggaaa tgatcaaagg aacagttttc agttcctgcg
     7261 gatggatgac ggtttgcttt gctaaaggat gatttcgatg tatcaaaagt ccccaacgat
     7321 cttgggctgg cagtcgaaat gactggtatt tttgtttgtt tgtcggttcg attacgagtc
     7381 caaaatcaag taatccgcta tccagtttgt ctatgatatc atctgcattc ccgctatata
     7441 aatgaaactg gatatcagga tgcgccttga tcaacgaatg aaggctatca gaaatgaaag
     7501 agattgcttt agtttcgcct ccgccaatgt agatttctcc agagatgatt gcgtcatttg
     7561 ttaaattgtt cgccgttttt tctaccaacg acaagatttc ttttcctttt gaataaagat
     7621 atcgaccaga atccgtcaac tgtatctctc gggagccccg agtgaaaagt gtcacaccaa
     7681 gttcttcttc taaatctttc agttgttttg agagagtagg ttgcgtgata tgcagagatt
     7741 ttgctgctcg gctgatattt ttttctctag ctactgctaa aaaatacgtc agtatacgaa
     7801 tatccatttt ttccctcctg tttttaaaaa agcataccac taagtatagt taaaaggaat
     7861 agttaagtat gttttataag tattagacat gataagccgt ccgttataaa gtaaggataa
     7921 aaggagggag caaaatgaca agcctcatcg aaaaacaaat cgtcaataaa gagattcgag
     7981 taacggatcc gctctttgaa gtgatccatc agatccaagc tgaaaacgaa gagcctttag
     8041 cagcgctgaa tactgggtac catgaaccag cagatatccg caaacggcta gaaaatatca
     8101 ttagtgacaa agtagatgat acggtgactg ttctgctgcc tttttataca gatttcggca
     8161 aacatattag tatagggaaa aatgtcttta tcaatcgtca agtgatgttc gttgacttag
     8221 gtggcatctg tttagaagat tcagtattga ttggtcctcg tgtcaacctc atcacggtga
     8281 accatctaac cgatccaaaa gaacgaagag gcttgtcagt aaagccaatc cacatcaaga
     8341 aaaatgcttg gatcggagca ggagcaacta ttctgccagg cgtaacgatt ggcgagaatg
     8401 ccattgttgc agcgaatgca actgttacga aagatgtccc agacaatacc atcgttgcag
     8461 gaatccctgc caaaatcgtc aaacctgtcg aacggattat ttgaacagta agatgaaata
     8521 agagatagtg agtataagca agagattttt caaaacagga ggagaataga atgaatgatt
     8581 tatcagaaaa agtgattgtc atcatgggcg cttcaagcgg aatcggtgaa gcaacaacga
     8641 agctattagc agaaaaaggg gctaaactag ttatagctgc acgccgagaa gatcgcctaa
     8701 aagcaataaa agaatcttta ccagaagctg agctatatat tcaaacagca gatgtaagag
     8761 attttgcaca agtccaagca gttatcgatt tagcgatgga aaagttcggt cgaatcgatg
     8821 tattgtacaa taatgcagga atcatgccaa ccgctccatt agttgaaggt caccgtgatg
     8881 aatggcaaaa tatgcttgat atcaacatca tgggtgtgtt aaatggaatt tccgccgtac
     8941 ttccaatcat ggaaaaacaa aaatctgggc atatcatttc aactgattct gtggcgggac
     9001 atgttgttta tcctgattcc gccgtttatt gcggaacaaa atttgctgtc cgtgcaatca
     9061 tggaaggatt acgtcaagag caacggcaaa ataacatcaa atctacgatc atctctccag
     9121 gagctgttca aactgaatta tatcaaacca tcagcgacaa aaaggctgct cttgaacttc
     9181 atgaagcgca aaaagaatgg ggattgacct ccgaagatat agcttctgct gtagcatttg
     9241 cgatagaaac gccagaccgg atgtctgtca gtaacatgat tatccgtccg acgacacagg
     9301 aagtataatc cataacggat aatatccaaa gagaattact tgttaaatag ttattcaaac
     9361 gaccatcaat ttaaggcgtg aatggagaag aatattcttc atttacgtct ttttatgtag
     9421 aaaaagcaaa ttcatcaaaa agaaacaaat gttatttaaa tatggacatt gacttgcttt
     9481 tactttttta gttacactgt tatttaggaa aagtttcata attcaaagga gaaaaaagat
     9541 gaaagcaaag aatttattat ttagcgttat tcttttagga aatctagcag ttgccaacac
     9601 aacagtgcta gctgaagaat cgacagaaac tgtcgcaact cagacatcga gttcttcaga
     9661 aacaggaatt gaaaacgata cagagagtac tttgcagtca gctactgtct cagaaaatac
     9721 aatttcaacc gaagaaccaa caactgaaac aacagaacaa acacaaaccg aagacagtac
     9781 atcagcagaa gctcagaaca atccagagaa tgcagaagaa atcacgaacc aattgacaga
     9841 tgggcaaaca ttgacacata cccatcaagc agatttgtct gaattcgaaa actatactgg
     9901 ctatgctttt tatgctcgct catctgctaa ttctcaacaa gcgttcattg atagtattgc
     9961 ctcaactgca caaagtttgg caagtgccaa tgacttatat gcatcagtca tgattgctca
    10021 agccatcgtt gaaagtggct gggggaacag tactttggct tctgccccta attacaatct
    10081 atttgggatt aaaggaagct ataatggcca atctgttacg atgcctactt cggaatatgt
    10141 gaatgggcaa tggattacgg tgaatgccgc ttttagaaaa tatccttcgt acaaagaatc
    10201 attgcaagat aacgtaacgg tattgaagac gacttctttt cagccaggcg tttactacta
    10261 ttccggtgca tggaaaagca atacgaactc ttacaaagat gctacggctt ggctaacagg
    10321 tcgttatgcc actgcgccta attatggttc tacattgaac aatgtaatcg aaacctataa
    10381 tctgacacag tatgatacag caccaacttc aacttctccg atgtatcgtc tgtataaccg
    10441 tcatacagga gaacatttat atacattgaa tgccggagaa aaaaattatc tgccaactgt
    10501 aggctgggaa tatgaaggga ttgcttggca agcaccaaac agcggacaac ctgtctaccg
    10561 tttatacaat ccttacagtg gagaccatca ttacacaatg gcacaatctg agatcaactc
    10621 tttaacaaaa atcggttggc gttatgaagg tctaagtttt tattctggtg gttccaagcc
    10681 aatttatcga ctatttaatc caaatgaaaa aactggtacc catcactata ccttgagtgc
    10741 taaggaaaga gattggctaa caccgatggg ctggagatat gaaggaatag gattttatgg
    10801 ttattaaaaa gaggtagtga aaaagctgcc ctgcatcaag tagtaagaac agccaaacaa
    10861 aaacagattt tcatgttttt tgtttggttg aacttattac cgcagatgca agtttttgaa
    10921 caccgtttac tcaaaaaagg ttgtgacaac atcttgtcat aactttttta ttactgttta
    10981 agcatactga tccaatttct aatattcgac gggattcttg caaaaggcga tttcggaaat
    11041 ttttggcggt gtaaaatttt ctactgcaga agagctatct tctatagttt gataagaatc
    11101 aataatcttg gttttagcgt tgtgctttct ttatcatttt ttccgttcat tctacaaaaa
    11161 atttcttttc tctatacttt tctattgaga gcgttttttt tattacacag ctgattcttt
    11221 gacttttttc tttttttatt ctattattga caagtcaatc gttgacgagt caattattag
    11281 aaaggaggaa attatgtctt tagaagagat tagtcacctt ttatatcaaa tcaaattagc
    11341 cgatcaaaaa atcgtccaga tctttgaaga aaatatcggt ataagtctta ctagatacga
    11401 gatcatgatg agactgaaag aagaaaatcc attgctacaa agcagtttgc aagaaaagtt
    11461 gcagattgat caaggagcag ttactcgtca tctgaaggta ttggaagcaa atggctatgt
    11521 ttcgcgtcag agaaatcctc agaacaaccg ggaagtgtat gtagcgctaa cagaaaaagc
    11581 ccagaagaaa atcgagcatt gtgaaatgga ccataaagat acaggttccg tgctatcccc
    11641 ggctttcagc gatgtagaaa tgaaacaatt tctaacactt ttagataaat tgaataccca
    11701 actttgcaat ataacaacag aaacgaaaga ggttaataat aatggaacaa aaaaatgatt
    11761 tttcaacaat tatgactggt agaagatccg ttcgcgtata tgatgaaaca tacaaaatcc
    11821 cacacgaaga aatgctggaa atgatcaaag aagcgacgac tgcaccttct tctgtcaata
    11881 tgcaaccatg gcgctttgtg gtcgctgaaa gcgaggaagc aaaagaaatc ttgcgtcctt
    11941 tgatccgttt caatacgaga caaaatgata cttcttctgc aatggtcatg atttttggcg
    12001 atatgcaatg ttacgaatat ggcgaagaaa tctataacca agcttacgaa tcagggaaga
    12061 tgccaaaaga agtcagagat caacaattag ctgcgatcat tccttattac aagagttttt
    12121 caagagaaga aatgaacgat gtagtcaaag tcgattctag cttagcggct atgcaattca
    12181 tgttagttgc gcgtgatcat ggctatgaaa caaatccaat tggtggattc gaagcagatc
    12241 agttggcaga ggcatttggt ttggataaag accgttatgt tccagttatt attttatcaa
    12301 taggaaaagc ggtagaagaa ggttacgagt ctgttcgttt agcaccagaa aagatcacta
    12361 cgttcgaata aaaggttttc agttactatt cagtagctat tgcttttttt gaatcgtgtg
    12421 tggtaaccta ataaaaaagg aggtcggaaa aatgactgca tcgatgaaat tacgtttcga
    12481 acttttgaat aacaactaaa taaattcaaa agacatgtat aaacaacaat ttcatggatg
    12541 gagtatgtcc attttttcga acgacagtag aataggtgaa agctatgaca gatttggtga
    12601 tttagtcata gttatttcgt tcagagtagg aaaagatgtg atgcagtttt tttgcaaaca
    12661 gatttttctg ctctttttta gtatcgataa ttgttgtttt acatgaaata ggagtgtaaa
    12721 acatatggaa aatttagcag taaatataac aaatctacaa gtcagctttg gcaaccagct
    12781 agaactatct attgattctc ttcgtgtcta tcagcaagat cgtataggga tcataggaga
    12841 aaatggtgtc ggtaaatcga ctttgctcaa actaatagcc ggtgaacttt ttcccgatca
    12901 tgggaaaatc caaacagaga tcaccttcaa ctacctgcct caattaacct atctcgctga
    12961 agcaaaggac ctaaatttgg aattagccag tcatttccag ttaagactgg aagaaacttc
    13021 agagcggaaa tggagcggag gggaagaacg aaagatcgag ttgatacgtc ttctttcttc
    13081 ttatgaacaa gggatgcttc tagacgagcc aacaacccat ctagatagaa aaagtattga
    13141 tcgactgatt gaagagcttc gttattatta tggtacgctg gtttttgtta gtcatgatcg
    13201 ctattttcta gatgagctag catcgaaaat ctgggaagta aaagacggag aaatccgaga
    13261 gttttcgggg aattatagtg cctatctcac tcaaaaggaa ttggagaaaa agactcagct
    13321 acgagaagca gagtcgatca tgaaagagaa aaaacgattg gaaaaatcga tccaagaaaa
    13381 gaaaaaacaa gcggaaaagt tggaaaaagt gtccagtaaa aagaaaaagc aacaaatcag
    13441 accggatcgg ttgtcttcct ctaaacaaaa agacagtgta caaaaagcca tccaaaagaa
    13501 tgcgaaaaca ttagagagaa gactccaaaa aataggagaa acaaccaagc cgcagcagat
    13561 gaaacaaatc cgttttccag taccaaaatc tcttgaactc cacagccgct atcccatcat
    13621 gggacaaaat gtccaattgg aaagaagtgg gagaacatta ctggtaaatg gtgattttca
    13681 gttttcttta ggtaaaaaaa tcgcgattgt cggtgaaaat ggttcaggta agacaacctt
    13741 attagaacat atccgcaaac aaggagaagg aatccttctc tctccgaaag taagctttca
    13801 agtatatcag caaaagggtt atcaaatgac atctgaagaa tccatcattc gttttgtcat
    13861 gagacaaaca gagttttcag aatcgcttgt ccgtagtttg ctgaatcact tagggtttgc
    13921 tcaggaaact ttgacgaaac cgttatgtac attaagtggg ggagaagcga cccgtctgac
    13981 gattgctttg ctttttacta agccaagtaa tgtgttgctg ttagatgaac cgactaattt
    14041 tattgatatg gcaacgatcg aagctttaga gaagctaatg caaatatatc cgggaacgat
    14101 tttgtttact tctcatgatt cttactttgt cgagcgtacg gctgatgaag tttatgaaat
    14161 aaaagggcag aaaataaaaa aagtacttac gagaaatttt taaatgtgct acgatgattt
    14221 tcgtgacaaa tttaaaggag tggtacagat tgcctacaaa taaaaaagaa ggaataattt
    14281 ttacaacaat gatgtgtttt ttgatggtct tggggatgag cgcgtataat ttatggctgc
    14341 atcaagatct tcatttatca agtttgttga ttggtctagt gcctggattc gtggtggctt
    14401 tcattttgga tgtcttcatc atcggtgtgc tggcgaaaaa aattgccttt aaactaccag
    14461 taaatccaga aagcaaggtc caaatgatct taactatttc atgcttgatg gttttaggaa
    14521 tggtgacatg tatgtcttta ttcggtgtga tcatggaaca aggaatacct gatcaattat
    14581 tctctgctta tatgaatgct tggaaaatga atgtgattgc cgctttaccg ttgcagttga
    14641 tcatcgttgg cccgctttca agaagtgtgc taaaagcaat tcaaagtaat gaatgatgga
    14701 acactgttat ttgaaaaaag gccttggcat gctttttgtc atagtctctt gaatgcagtt
    14761 ctagaaaaat agtgatccga acgataggtt ttggcctgtc gttcggatcg ctttttcttt
    14821 tccaactgta ttgctctttt attgaagata atttgctctt caatagatat ttctagaaag
    14881 gttctgttta tcccttactc aaaaaactgc tgcatttgtt ctcttacttg ctgacaccat
    14941 tggagttcct gctgacaaag cataattctg cgctggatca caacataacg tccaaattct
    15001 tgtttcttgt ctagcgagag gtcattcaat tttttttgat ttttttgcat gattttgttc
    15061 agctgttgtt ctctagtgaa tagcagtcca gtagctgttg ttttatcgag cgtcgaaaaa
    15121 gcatagattt ttgctagaaa ttcatctttt tgcgtaggag cgggagtttc ctctttgatc
    15181 cattcctcta caagagcacg tccttcatca gtcaagtggt agatcttttt ttgagagtgc
    15241 tcgtctttgt ccaaaacggt cacataaccc tgctggtcta acttggcaag cgttgtatag
    15301 atctgactgt gatgggcttc ccaaaaaatt gtgatcagct gcttcaattc atacccagaa
    15361 cgtggtttgg ataaaagcac gcataataat atataggcta aagtattcat aaaaatccta
    15421 cctctcgtct tattttcttt attatatcac agtaaagttt ccacgtttta catgtgcata
    15481 tttacatgta aaataaatca tgtatgatgc taatagagag aaagggatgg aaatattgga
    15541 gaatcaaata gatatacaag aacaaacaaa tgaagaaaca aaggggaaaa gttcagcgct
    15601 agttgtagca gctacctgta tgatcgcttt tatgggagtg ggtctagtag acccaatctt
    15661 aaaaacgatt gctgcacagt taaacgctac gccagctgaa acgaccctgt tatttactag
    15721 ttacatgtta gtcactggtg tggtgatgct atttacaggt ttcttatcta gtcggatcgg
    15781 tttgaaaaaa acattgatga caggattgtt tatcatcgtt gtattcgctg gtcttggcgg
    15841 attatctggg aatatcggaa tgctgattgg gttacgtgcc ggctggggtg tcgggaatgc
    15901 tttatttgtc tctactgctt tagcaacgat cgtcagtatt ttagttggta acacagaaaa
    15961 agcaatcatg atgtatgaag cagcacttgg ctgcggaatg gctgttggcc ctctagtcgg
    16021 tggggtcttg ggcagtggtt catggcgtta tccatttttt ggggtagcat ttttgatgtt
    16081 ttgcggtttt atagccctag cggtactttt acctgaaact gagaaaccaa agagaaaagt
    16141 aggcctttgg gaaggtgtca aagcgttaag caatcataaa cttcgttcag ttggactaat
    16201 cgcattgtta tataatttcg gattctttac tttacttgcg tatgcgccat ttttattgat
    16261 tggctattct gaattagaag tcggttttgt attttttggc tggggtgtgc ttctggctat
    16321 tgcttcgatt ttcgttgcac cggctcttga gcggaagttt acgacttatc ggacaatttt
    16381 agcagcattt gtcttattca ttatttgttt gctgttatta ggagctggaa cttctatgcc
    16441 agtccttgta ccgatcagca ttgtgttagc aggatttttc caaggaatta tcaatacact
    16501 gttgacgacg attgctatgg aaataccagg tctgcaacga aacgttgctt cgtccagcta
    16561 tagttttgtc cgctttttcg gtggagcttt agcaccattt attgcaggtg tgattggtga
    16621 acatattggt gaaagctatg cgttttattt tgcaggtgcc attgttctta tcagtgtatg
    16681 ttgtatcatt tatcaccgta attattttgc tacaaatgaa gaagaataag aaatcagagg
    16741 ttgtgaaaaa gctgtcctgc atcaagtcat aagaa
//
LOCUS       DARPZJ010000203         7959 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.089, whole genome shotgun sequence.
ACCESSION   DARPZJ010000203 DARPZJ010000000
VERSION     DARPZJ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.089"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            128..1564
                     /locus_tag="SLE23_003032"
     CDS             128..1564
                     /locus_tag="SLE23_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEI8469832.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="SLE23_003033"
     CDS             1753..4200
                     /locus_tag="SLE23_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEI8469833.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="SLE23_003034"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="SLE23_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEI8469834.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="SLE23_003035"
     CDS             complement(5690..6793)
                     /locus_tag="SLE23_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEI8469835.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="SLE23_003036"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="SLE23_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEI8469836.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DARPZJ010000204         7777 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.091, whole genome shotgun sequence.
ACCESSION   DARPZJ010000204 DARPZJ010000000
VERSION     DARPZJ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.091"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            242..1210
                     /locus_tag="SLE23_003037"
     CDS             242..1210
                     /locus_tag="SLE23_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEI8469837.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1203..2234
                     /gene="vanA"
                     /locus_tag="SLE23_003038"
     CDS             1203..2234
                     /gene="vanA"
                     /locus_tag="SLE23_003038"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEI8469838.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2240..2848
                     /locus_tag="SLE23_003039"
     CDS             2240..2848
                     /locus_tag="SLE23_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEI8469839.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3276..4187
                     /gene="vanY"
                     /locus_tag="SLE23_003040"
     CDS             3276..4187
                     /gene="vanY"
                     /locus_tag="SLE23_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEI8469840.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4340..4825
                     /gene="vanZ"
                     /locus_tag="SLE23_003041"
     CDS             4340..4825
                     /gene="vanZ"
                     /locus_tag="SLE23_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEI8469841.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5112..5441)
                     /locus_tag="SLE23_003042"
     CDS             complement(5112..5441)
                     /locus_tag="SLE23_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEI8469842.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5746..6075
                     /locus_tag="SLE23_003043"
     CDS             5746..6075
                     /locus_tag="SLE23_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEI8469843.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6065..6352
                     /locus_tag="SLE23_003044"
     CDS             6065..6352
                     /locus_tag="SLE23_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEI8469844.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6631..7194)
                     /locus_tag="SLE23_003045"
     CDS             complement(6631..7194)
                     /locus_tag="SLE23_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEI8469845.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2565 a         1297 c         1545 g         2370 t
ORIGIN      
        1 ctggtgtcat ccaccaacat caaaaagtat agagccataa ttttttagga aaatctcaag
       61 gttatcttta ctttttctta ggaaattaac aatttaatat taagaaacgg ctcgttctta
      121 cacggtagac ttaataccgt aagaacgagc cgttttcgtt cttcagagaa agatttgaca
      181 agattaccat tggcatcccc gttttatttg gtgcctttca cagaaagggt tggtcttaat
      241 tatgaataac atcggcatta ctgtttatgg atgtgagcag gatgaggcag atgcattcca
      301 tgctctttcg cctcgctttg gcgttatggc aacgataatt aacgccaacg tgtcggaatc
      361 caacgccaaa tccgcgcctt tcaatcaatg tatcagtgtg ggacataaat cagagatttc
      421 cgcctctatt cttcttgcgc tgaagagagc cggtgtgaaa tatatttcta cccgaagcat
      481 cggctgcaat catatagata caactgctgc taagagaatg ggcatcactg tcgacaatgt
      541 ggcgtactcg ccggatagcg ttgccgatta tactatgatg ctaattctta tggcagtacg
      601 caacgtaaaa tcgattgtgc gctctgtgga aaaacatgat ttcaggttgg acagcgaccg
      661 tggcaaggta ctcagcgaca tgacagttgg tgtggtggga acgggccaga taggcaaagc
      721 ggttattgag cggctgcgag gatttggatg taaagtgttg gcttatagtc gcagccgaag
      781 tatagaggta aactatgtac cgtttgatga gttgctgcaa aatagcgata tcgttacgct
      841 tcatgtgccg ctcaatacgg atacgcacta tattatcagc cacgaacaaa tacagagaat
      901 gaagcaagga gcatttctta tcaatactgg gcgcggtcca cttgtagata cctatgagtt
      961 ggttaaagca ttagaaaacg ggaaactggg cggtgccgca ttggatgtat tggaaggaga
     1021 ggaagagttt ttctactctg attgcaccca aaaaccaatt gataatcaat ttttacttaa
     1081 acttcaaaga atgcctaacg tgataatcac accgcatacg gcctattata ccgagcaagc
     1141 gttgcgtgat accgttgaaa aaaccattaa aaactgtttg gattttgaaa ggagacagga
     1201 gcatgaatag aataaaagtt gcaatactgt ttgggggttg ctcagaggag catgacgtat
     1261 cggtaaaatc tgcaatagag atagccgcta acattaataa agaaaaatac gagccgttat
     1321 acattggaat tacgaaatct ggtgtatgga aaatgtgcga aaaaccttgc gcggaatggg
     1381 aaaacgacaa ttgctattca gctgtactct cgccggataa aaaaatgcac ggattacttg
     1441 ttaaaaagaa ccatgaatat gaaatcaacc atgttgatgt agcattttca gctttgcatg
     1501 gcaagtcagg tgaagatgga tccatacaag gtctgtttga attgtccggt atcccttttg
     1561 taggctgcga tattcaaagc tcagcaattt gtatggacaa atcgttgaca tacatcgttg
     1621 cgaaaaatgc tgggatagct actcccgcct tttgggttat taataaagat gataggccgg
     1681 tggcagctac gtttacctat cctgtttttg ttaagccggc gcgttcaggc tcatccttcg
     1741 gtgtgaaaaa agtcaatagc gcggacgaat tggactacgc aattgaatcg gcaagacaat
     1801 atgacagcaa aatcttaatt gagcaggctg tttcgggctg tgaggtcggt tgtgcggtat
     1861 tgggaaacag tgccgcgtta gctgttggcg aggtggacca aatcaggctg cagtacggaa
     1921 tctttcgtat tcatcaggaa gtcgagccgg aaaaaggctc tgaaaacgca gttataaccg
     1981 ttcccgcaga cctttcagca gaggagcgag gacggataca ggaaacggca aaaaaaatat
     2041 ataaagcgct cggctgtaga ggtctagccc gtgtggatat gtttttacaa gataacggcc
     2101 gcattgtact gaacgaagtc aatactctgc ccggtttcac gtcatacagt cgttatcccc
     2161 gtatgatggc cgctgcaggt attgcacttc ccgaactgat tgaccgcttg atcgtattag
     2221 cgttaaaggg gtgataagca tggaaatagg atttactttt ttagatgaaa tagtacacgg
     2281 tgttcgttgg gacgctaaat atgccacttg ggataatttc accggaaaac cggttgacgg
     2341 ttatgaagta aatcgcattg tagggacata cgagttggct gaatcgcttt tgaaggcaaa
     2401 agaactggct gctacccaag ggtacggatt gcttctatgg gacggttacc gtcctaatcg
     2461 tgctgtaaac tgttttatgc aatgggctgc acagccggaa aataacctga caaaggaaag
     2521 ttattatccc aatattgacc gaactgagat gatttcaaaa ggatacgtgg cttcaaaatc
     2581 aagccatagc cgcggcagtg ccattgatct tacgctttat cgattagaca cgggtgagct
     2641 tgtaccaatg gggagccgat ttgattttat ggatgaacgc tctcatcatg cggcaaatgg
     2701 aatatcatgc aatgaagcgc aaaatcgcag acgtttgcgc tccatcatgg aaaacagtgg
     2761 gtttgaagca tatagcctcg aatggtggca ctatgtatta agagacgaac cataccccaa
     2821 tagctatttt gatttccccg ttaaataaac ttttaaccgt tgcacggaca aactatataa
     2881 gctaactctt tcggcaggaa acccgacgta tgtaactggt tcttagggaa tttatatata
     2941 gtagatagta ttgaagatgt aaggcagagc gatattgcgg tcattatctg cgtgcgctgc
     3001 ggcaagatag cctgataata agactgatcg catagagggg tggtatttca caccgcccat
     3061 tgtcaacagg cagttcagcc tcgttaaatt cagcatgggt atcacttatg aaaattcatc
     3121 tacattggtg ataatagtaa atccagtagg gcgaaataat tgactgtaat ttacggggca
     3181 aaacggcaca atctcaaacg agattgtgcc gtttaagggg aagattctag aaatatttca
     3241 tacttccaac tatatagtta aggaggagac tgaaaatgaa gaagttgttt tttttattgt
     3301 tattgttatt cttaatatac ttaggttatg actacgttaa tgaagcactg ttttctcagg
     3361 aaaaagtcga atttcaaaat tatgatcaaa atcccaaaga acatttagaa aatagtggga
     3421 cttctgaaaa tacccaagag aaaacaatta cagaagaaca ggtttatcaa ggaaatctgc
     3481 tattaatcaa tagtaaatat cctgttcgcc aagaaagtgt gaagtcagat atcgtgaatt
     3541 tatctaaaca tgacgaatta ataaatggat acgggttgct tgatagtaat atttatatgt
     3601 caaaagaaat agcacaaaaa ttttcagaga tggtcaatga tgctgtaaag ggtggcgtta
     3661 gtcattttat tattaatagt ggctatcgag actttgatga gcaaagtgtg ctttaccaag
     3721 aaatgggggc tgagtatgcc ttaccagcag gttatagtga gcataattca ggtttatcac
     3781 tagatgtagg atcaagcttg acgaaaatgg aacgagcccc tgaaggaaag tggatagaag
     3841 aaaatgcttg gaaatacggg ttcattttac gttatccaga ggacaaaaca gagttaacag
     3901 gaattcaata tgaactatgg catattcgct atgttggttt accacatagt gcgattatga
     3961 aagaaaagaa tttcgttctc gaggaatata tggattacct aaaagaagaa aaaaccattt
     4021 ctgttagtgt aaatggggaa aaatatgaga tcttttatta tcctgttact aaaaatacca
     4081 ccattcatgt gccgactaat cttcgttatg agatatcagg aaacaatata gacggtgtaa
     4141 ttgtgacagt gtttcccgga tcaacacata ctaattcaag gaggtaagga tggcggaatg
     4201 aaaccaacga aattaatgaa cagcattatt gtactagcac ttttggggta acgttagctt
     4261 tttaatttaa aacccacgtt aactaggaca ttgctatact aatgatacaa cttaaacaaa
     4321 agaattagag gaaattatat tgggaaaaat attatctaga ggattgctag ctttatattt
     4381 agtgacacta atctggttag tgttattcaa attacaatac aatattttat cagtatttaa
     4441 ttatcatcaa agaagtctta acttgactcc atttactgct actgggaatt tcagagagat
     4501 gatagataat gttataatct ttattccatt tggcttgctt ttgaatgtca attttaaaga
     4561 aatcggattt ttacctaagt ttgcttttgt actggtttta agtcttactt ttgaaataat
     4621 tcaatttatc ttcgctattg gagcgacaga cataacagat gtaattacaa atactgttgg
     4681 aggctttctt ggactgaaat tatatggttt aagcaataag catatgaatc aaaaaaaatt
     4741 agacagagtt attatttttg taggtatact tttgctcgta ttattgctcg tttaccgtac
     4801 ccatttaaga ataaattacg tgtaagatgt ctaaatcaag caatctgatc tttcatacac
     4861 ataaagatat tgaatgaatt ggattagatg gaaaacggga tgtggggaaa ctcgcccgta
     4921 ggtgtgaagt gaggggaaaa ccggtgataa agtaaaaagc ttacctaaca ctatagtaac
     4981 aaagaaagcc caattatcaa ttttagtgct gaggaattgg tctctttaat aaatttcctt
     5041 aacgttgtaa atccgcattt tcctgacggt acccccaaac taagatttca tagatagatt
     5101 ttctgataac tttaaaaaac acgaatagcg gaaaggatgt cttcattcgc taaagagtaa
     5161 taaactactt ttccatcttg acgtgatttt gccattccat gtttttttaa aaaacgtaaa
     5221 tggtgtgacg ttgtagcgac actagcagta agtatttctg ctaaatcaca gacgcacatt
     5281 tccttatagg tttctaaagc atagaaaatt ttaattctag aaaaatcgct gaaacatttc
     5341 cctaacacaa gtaagtttga aaaatctttt tgatccaatt tattttttat tccatttact
     5401 ttttctttat gtacgacagt cacttggcaa acttttttca ttcatctcac ctcacattca
     5461 aacgattatt tgaatgaagt atacctattt gatcactctt ttgtcaatct accttaattc
     5521 caatacacta ttataagcaa tttcatgtat tgaagtaaac ttacttgcaa gtgcgttttt
     5581 gattccaagt taaaaacata ttattattct acataatttc ctaatcaaat aaaactcctt
     5641 tgaaaattgt tctaaaggag ttttattatt ttgtatttct actaaaaata gcgtacaatg
     5701 taattactaa gtaattacga aatgtaaaat aatggaggaa ataatatgat tacaaaaaca
     5761 agaaaacaag gaaattctat tatgttaacg gtccctaaag aattcgatgt gcccaatggt
     5821 gttgaagtag aagctaagct tgtagagaat ggtatccttt atgagtttgt agagcctaaa
     5881 aaagaatttt ttgattttag tgaagatatt ttggctgata ttctttcaga aggttatagc
     5941 aaacaagaga tcttaaaaga atttagaaat agaaaaaatg cgttaacttc tgcatttaaa
     6001 tctattgctg aagatactgt tgcaaattct aaaccgatga caaaagagga gttggcagca
     6061 gaaattggct tatgagattc taccttctaa acacgtaata aagtatctaa aaaaattaaa
     6121 agagaaaaca ttaaaagaac aatttttaac gataatttat gatgagatag cagttcgtcc
     6181 tcattcggga gaacaaaaaa cgggtgattt atcaggaatt tgggctattg gattcaagta
     6241 tgcaggtacg acatatcgcg ttgcatatga aattaaagat aatgcagtga tacctatctt
     6301 actatgtgga acgcatgaaa atttttatga acaattaaaa aagattaggt aagaacccaa
     6361 tgtttcaact tgagaggata gacgacactt taaaagataa tttttaacag ctgagagttg
     6421 taatacccta taattttaaa ccactaacct atatatttat gaaaaataga aaaaattaaa
     6481 acgcatttta agcctctttc aaattaaaag cttcatcctt atgcacaaag agggcttaaa
     6541 atgcgttatt ttatattgtt ttttagtaat aataaaaaaa tcactctaat tctcccataa
     6601 atattataga ttcctaaaga ttaaaataga ttattcccta ttgtctttta agtagcggta
     6661 gagtgttgcc ttgctaatac cagtcatttc cgtaatttct tttacgctat aaacctgact
     6721 tttatacaat tttactgctc gatcaacatc tttctggttc actcgtggac ggccaccttt
     6781 acgacctctc gcacgtgcac ttttcaaacc ttctttggta cgttcaacaa ttaaatcacg
     6841 ttcgaactga ctaaatgctt ggaagacagt catcattaag cgtccgtgag gcgtgctggt
     6901 atcgaagttt tctttcaagc tcaccagctt aacatggtgt tcttcaaaat aggtaacaag
     6961 gtcaatcaaa tcctttgtac tacgacccaa tcgagaaaaa ctttctacaa ttaccgtatc
     7021 tcccggacga attttatctt ttaaacgatt tagttgggga cgaaccgctt tggttcccgt
     7081 cattttctca gttaggattt cattacaatt ttgttcattg agtaagtcta attgacgatt
     7141 tagttcttgt gaacgtgtac tcactcgggc ataaccataa atgtatccac tcatgctttt
     7201 cttcctttcg tactttaatt ctggcttgat tgtatcataa aagggagtta tagatacata
     7261 gttaatgcaa caagttatga tacaaaatat gacctctttt atttaataaa agaggtcatt
     7321 tcattttgtc tcataatcga ttgtttttga tacgagtgtg tatacgaaat aaacaaaaaa
     7381 atcttaagta aatttctaga tacctaattt aatcctaact agtgtatcct aaagttaata
     7441 acgagtttat cacaatgaaa attataaaat gctcccatat tagatataac atgcaatatt
     7501 tgaattagaa ctacaaaatt tattcgtttt ataaagtaaa taatgttgag atactaagga
     7561 atagaatatt ataaggaatt gagctgaatg tattggataa aaaaagaata actttattag
     7621 agatggacta taaaaatgct cgtaattttc ttctgaagtc tgaaagctat ttgaatgctc
     7681 agctaccaga atatattagt tttgacgaaa ctttaaaatc tgctaaaaaa gttttaactt
     7741 cgccgtttgt ataattaagc gagacaaata aaaaagc
//
LOCUS       DARPZJ010000205         6752 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.098, whole genome shotgun sequence.
ACCESSION   DARPZJ010000205 DARPZJ010000000
VERSION     DARPZJ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.098"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            111..194
                     /locus_tag="SLE23_003046"
     CDS             111..194
                     /locus_tag="SLE23_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEI8469846.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="SLE23_003047"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="SLE23_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEI8469847.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="SLE23_003048"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="SLE23_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1649..2314
                     /locus_tag="SLE23_003049"
                     /pseudo
     CDS             1649..2314
                     /locus_tag="SLE23_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2350..2595
                     /locus_tag="SLE23_003050"
     CDS             2350..2595
                     /locus_tag="SLE23_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEI8469848.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2698..3567
                     /locus_tag="SLE23_003051"
     CDS             2698..3567
                     /locus_tag="SLE23_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEI8469849.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3548..4282
                     /locus_tag="SLE23_003052"
     CDS             3548..4282
                     /locus_tag="SLE23_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEI8469850.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4315..5230
                     /gene="ant(6)"
                     /locus_tag="SLE23_003053"
                     /pseudo
     CDS             4315..5230
                     /gene="ant(6)"
                     /locus_tag="SLE23_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5227..5769
                     /gene="sat4"
                     /locus_tag="SLE23_003054"
     CDS             5227..5769
                     /gene="sat4"
                     /locus_tag="SLE23_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEI8469851.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5862..6656
                     /locus_tag="SLE23_003055"
                     /note="aph(3')-IIIa"
     CDS             5862..6656
                     /locus_tag="SLE23_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEI8469852.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2366 a         1016 c         1407 g         1963 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag tggaaagacc
     1561 tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata atataggtga
     1621 ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa accaactttg
     1681 tttgcctata gatcttgaaa ttaaattaga agaaaatgat tttgctcatg ccattgtgca
     1741 gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta tgggtagacc
     1801 ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc aaggggttta
     1861 ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct acttatctca
     1921 agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga ttatgaacga
     1981 tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg gcttaatcag
     2041 tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata aatactcttt
     2101 cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag cccttgaaaa
     2161 ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt taaaggatga
     2221 actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg aaaatcaatt
     2281 aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta ttaataagga
     2341 gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga aactgaaaat
     2401 ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt ggggaatagg
     2461 atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt tagcaaaatg
     2521 aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta taaaaagaca
     2581 attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg ttgagtagaa
     2641 gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc atgcttgatg
     2701 gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta tatagaaggt
     2761 attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga tatagatatc
     2821 ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt cgctacaaag
     2881 ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg tgattggatt
     2941 aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt acgtgatatt
     3001 aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc caattatcag
     3061 actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc gattagcaaa
     3121 atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga aacttatccc
     3181 aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt ctctttaatg
     3241 tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca tgtttttcgt
     3301 atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg tatcaacgaa
     3361 aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata taccgagaag
     3421 gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga catgaccgag
     3481 aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3541 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     3601 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     3661 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     3721 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     3781 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     3841 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     3901 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     3961 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4021 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4081 gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct
     4141 aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga
     4201 gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt
     4261 atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga
     4321 tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga
     4381 attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat
     4441 tatgatatta catattttgt aagtgatata gaacctagaa ccgtttatat ctaatgatga
     4501 ctggcttaat caatttggga atataataat gatgcaaaag ccggaggata tggaattatt
     4561 cccacctgaa gaaaagggat tttcctatct tatgctattt gatgattaca ataaaattga
     4621 tcttacctta ttgcccttgg aagagttaga taattaccta aagggcgata aattaataaa
     4681 ggttctaatt gataaagatt gtagaattaa aagggacata gttccgactg atatagatta
     4741 tcatgtaaga aagccaagcg caagggagta tgatgattgc tgcaatgaat tttggaatgt
     4801 aacaccttat gttattaaag gattgtgccg taaggaaatt ttatttgcta ttgatcattt
     4861 taatcagatt gttcgccatg agctgctgag aatgatatca tggaaggtcg gcatcgaaac
     4921 aggctttaaa ttaagtgtag gcaagaacta taagtttatt gaaaggtata tatccgagga
     4981 tttgtgggag aaacttttgt ccacctaccg gatggattcc tatgaaaaca tatgggaagc
     5041 attatttcta tgccatcaat tgttcagggc ggtatccggt gaggtggcgg aaaggcttca
     5101 ttatgcctat ccggagtatg ataggaatat aacaaaatat accagggaca tgtataaaaa
     5161 atacactggt aaaaccggct gcctggatag cacatatgcc gctgatatag aagagaggcg
     5221 ggaacagtga ttacagaaat gaaagcaggg cacctgaaag atatcgataa acccagcgaa
     5281 ccatttgagg tgataggtaa gattataccg aggtatgaaa acgagaattg gacctttaca
     5341 gaattactct atgaagcgcc atatttaaaa agctaccaag acgaagagga tgaagaggat
     5401 gaggaggcag attgccttga atatattgac aatactgata agataatata tctttactac
     5461 caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat
     5521 atagaagata tcgccgtatg taaggatttc agggggcaag gcataggcag cgcgcttatc
     5581 aatatatcta tagaatgggc aaagcataaa aacttgcatg gactaatgct tgaaacccag
     5641 gacaataacc ttatagcttg taaattctat cataattgtg gtttcaaaat cggctccgtc
     5701 gatactatgt tatacgccaa ctttgaaaac aactttgaaa aagctgtttt ctggtattta
     5761 aggttttaga atgcaaggaa cagtgaattg gagttcgtct tgttataatt agcttcttgg
     5821 ggtatcttta aatactgtag aaaagaggaa ggaaataata aatggctaaa atgagaatat
     5881 caccggaatt gaaaaaactg atcgaaaaat accgctgcgt aaaagatacg gaaggaatgt
     5941 ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa cctatattta aaaatgacgg
     6001 acagccggta taaagggacc acctatgatg tggaacggga aaaggacatg atgctatggc
     6061 tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga acggcatgat ggctggagca
     6121 atctgctcat gagtgaggcc gatggcgtcc tttgctcgga agagtatgaa gatgaacaaa
     6181 gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag gctctttcac tccatcgaca
     6241 tatcggattg tccctatacg aatagcttag acagccgatt agccgaattg gattacttac
     6301 tgaataacga tctggccgat gtggattgcg aaaactggga agaagacact ccatttaaag
     6361 atccgcgcga gctgtatgat tttttaaaga cggaaaagcc cgaagaggaa cttgtctttt
     6421 cccacggcga cctgggagac agcaacatct ttgtgaaaga tggcaaagta agtggcttta
     6481 ttgatcttgg gagaagcggc agggcggaca agtggtatga cattgccttc tgcgtccggt
     6541 cgatcaggga ggatatcggg gaagaacagt atgtcgagct attttttgac ttactgggga
     6601 tcaagcctga ttgggagaaa ataaaatatt atattttact ggatgaattg ttttagtacc
     6661 tagatttaga tgtctaaaaa gctttaacta caagcttttt agacatctaa tcttttctgg
     6721 ctctttgtca aatgatgttg gtaaagagaa at
//
LOCUS       DARPZJ010000206         4459 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.119, whole genome shotgun sequence.
ACCESSION   DARPZJ010000206 DARPZJ010000000
VERSION     DARPZJ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.119"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            263..1477
                     /locus_tag="SLE23_003056"
     CDS             263..1477
                     /locus_tag="SLE23_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HEI8469853.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1508..1726
                     /locus_tag="SLE23_003057"
                     /pseudo
     CDS             1508..1726
                     /locus_tag="SLE23_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2145..2618
                     /gene="dfrF"
                     /locus_tag="SLE23_003058"
     CDS             2145..2618
                     /gene="dfrF"
                     /locus_tag="SLE23_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HEI8469854.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2745..3401
                     /locus_tag="SLE23_003059"
     CDS             2745..3401
                     /locus_tag="SLE23_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEI8469855.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3583..4113
                     /locus_tag="SLE23_003060"
     CDS             3583..4113
                     /locus_tag="SLE23_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEI8469856.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         1495 a          656 c          946 g         1362 t
ORIGIN      
        1 ttctgattca tcagtcccat aaattataga gccgaaaaaa tatctttaaa aataaaaaaa
       61 gacgaaaata aacggttttc tataaaaaga agaccgttta ttttttgtct ttatttgtgt
      121 gaaaaacgaa aaagagcaca acacatcaag cttttattaa ttgtctgtct tttataaatg
      181 caagtattaa ttcaaaaaaa cagaagaaaa aaacaactac accttctttt atactcgtaa
      241 tcgtagaaag gaggcgaaaa aaatgaatac attacctatc aatacaggag atacagcatt
      301 catgatttta tgtacagcaa tggtttgcct gatgactcct ggtctagctt ttttttacgg
      361 cggattagca cggaagaata atatactaac gatcatgtct caatcttttc tctccgttgg
      421 gataacaacg attatgtggg tatttggtgg attcggattg gcctttggac gggatatcgg
      481 cggtgttatt ggaaacccgg cagatttctt tttgatgaga catgttacaa gcttccccaa
      541 catgtttcat ggtgcaacga ttccattttt aatgttcttt ctttaccaac tgatgtttat
      601 cgtgattacc gttcctttga tgacaggagc ttttgcaggg agattgaatt taaaaggcta
      661 tattatactt gttatttttt ggaatctgct gatttatttc cctgtttgcc actggatatg
      721 gggtggcgga tttttggatc agatgggatt tagagatttc gctggtggag cagtcatcca
      781 cacgacagct ggattcggct ctttagcatg tatcctcaca cttggtcaaa gaaagattcc
      841 tttaggagaa agaagtcagc atagcagtct tatggcagct gctatcggta caggactgct
      901 ttggtttggc tggttcggtt ttaattccgg tggtgcactt cgagcagatg aacaagcagt
      961 caatgcattt ggttcaacat tcatcgctct tgcatttgcg atgattactt ggctgatcat
     1021 tgcaaaagta aaaggaaatg gctttgattt tgtcgacgta ctaacaggat ccgttgctgg
     1081 attggcagcc attacgcctt gtgccggtta tgtagaagca aaaagtgcca tgctgattgg
     1141 gatcattgcg ggtatcgtct gtcatgctgc tgttgatttt cgtaaaaaga aacaatggga
     1201 tgatgcactt gatgtgtggg gtgttcatgg catgggcgga ttcacaggta cgattctgat
     1261 agggatcttt gcatctaaca gccatttact aacgaatcca agcagctggt acttcttagg
     1321 gattcaagtg attggtgtca tcattactgc cgtgtatgcc tatgtgctga caacagtgat
     1381 tttaaaatcg gcgatgcact ttacaacgat cactactaca aaagaagaac aagaagaagg
     1441 attggacttt ttcttctttg gcaacaaact caattgaaac aaattcaaat agaaaagagg
     1501 aagattcatg caacaaagca aaacgaaaat tcctgcaaaa aaattaacgt tctttggctt
     1561 tttggctatg accatctcaa tggtcgtttc attatatgaa tatcccacat tcgcgacctc
     1621 aggcttcagc ttagtatttt tcttgttatt aggcggtttg ctatggttta tccctgtggc
     1681 attgtgcgca gcagagatgg caacggtgaa aggatgggaa aaaggtgttt cccaaacaaa
     1741 aagatattaa gaaacagccc atgtttacct gcttgcaaac aaaagaatat tgctactaga
     1801 ctaagagata ctacataagt gtgttggtat ctcttttttg ttgccgtgaa acagcagact
     1861 atttcatttc tgcttgatta ccttaaaact tattagtcta tggtttgtca agggcttgtt
     1921 gcgtgagaaa tgctgaatat caccctttac aaaacatagg ctgataagta acttttcaaa
     1981 agcagaaaag aaatggcaat gcttataaca atatgatata atgcagatga agacaaaaaa
     2041 ggaatttgtc gagctggtta gttcgagata attttgagtt tgttaagatg tggtgcactt
     2101 gatggaatca caggtacgac atcatattat ggaggatgaa atagatgata ggtttgattg
     2161 ttgcgaggtc aaagaataat gttataggca agaatggtaa tataccatgg aaaataaagg
     2221 gagaacaaaa gcaatttaga gagttaacaa cgggtaatgt ggttattatg gggcgaaagt
     2281 cttatgaaga aatcggtcat ccgttgccta atagaatgaa tattgttgtt tccaccacaa
     2341 cagagtatca aggagataat ttagtttcag ttaaatcatt agaagatgca ttattattgg
     2401 ctaaaggacg agatgtatac atatctggtg gatatggact atttaaggaa gctttgcaaa
     2461 tagtagataa aatgtatatc acagaagtag atttaaatat tgaagatgga gatacattct
     2521 ttccagaatt tgatatcaat gattttgaag ttttgatagg ggaaacactt ggtgaggaag
     2581 tgaaatatac gagaacattt tatgtaagga aaaaatgaat tgagtaaatt ttggatttag
     2641 ggtgttttca taaatatatt gctttttatg catatataaa ttgttgtaag acaaattcca
     2701 gtttgtatgg ggcgataaaa tcagaatttg agagaggatt gaatatgaat aaggaatggt
     2761 ctgaacttaa taaaacaatg caggcacaaa taaaaaagaa agatacttat aagaggggta
     2821 ttgatacttt acttacttta cgaagtcagt taatacaaac cttagtatct ttcaaagaag
     2881 aattatgcag agaagatttt aactcaatcc ccttcataaa cgctgatggt tatcatagta
     2941 agacgattgc ttattctatt tggcatattt tccgcattga agatatagtt gtgcatacag
     3001 tgataaatga agatgaacaa gtattttttg caggcaatta tcaagagcgt atcaattcac
     3061 ctatcattac aacaggaaat gaactcatga aacagcagat tgcagacttt tcaaaacagc
     3121 ttaatctgga agaattatat ttatatattt tcgaagtatg ggaaagcact gagaaaatgc
     3181 ttgaacggtt atcttatgat gaattgaaaa gaaaaatacc gaaagaaaga aaaggatact
     3241 tagaatcgtt gaatgtagta aacgacaatg aaaaagcaat ttggctgatt gattattggt
     3301 gtaataaaga tatttgtgga ctaattcaaa tgccgttttc aagacattgg attatgcaca
     3361 cagaagcctg tttgcgtata aagaacaaga tacattcata ggcaaaaatt tcagtttgta
     3421 gaactaagga aattggaatt taaggaggaa taaagtatgg ttagtgattt tataagagca
     3481 gcatttccat ggattttaat gggtttattt gtagcaatca gttgttccct tatgagtaaa
     3541 aaagagaaat aaattcctgt ttgtatttat aaaagagaaa aaatgagaaa agtagtttta
     3601 tttattgcca tgagccttga cggatatatt gcggacggta atggtggagt agcttggcta
     3661 aatggtcatg gaaatgacaa tgaaaacatc gacacttata cagaatttac caaagatata
     3721 gatactgtct taatggggtg gaatacttct catcaggttg ttactgaact ttctccgcaa
     3781 gaatgggtat ataataaatt tacaacttat gtattaacac ataaagagtg caattcttcc
     3841 caacaaattc attttacaag tgaaaatcct gttttattat tggaacggct aaaacaagaa
     3901 gcaggaaagg atatttggat ttgtggcgga gcaaatcttg ttcagcagtt ggtaagcaaa
     3961 aatatgattg ataaatatta catttctgtt attcctactc tgttaggaaa tggggttcgt
     4021 cttttgggca acatagacag ggaaataaag ttaaggcttt gtaaaacaca gacttataac
     4081 ggaataaccg atttgattta tatgcgtaga taactagaga gaaacagaaa agctgttaaa
     4141 ccgacggagc gatccgacca cgttggcggg aaaatcctta agatttttcc gccatgcttg
     4201 caagggggcg gttcgcttcg gcggttcggc gagcttgcga gccgttcaaa gcccccgtta
     4261 tctaacaagg ggggcacaaa aaacaagaaa cactatacac taacaagcgg aaaacgctgt
     4321 atttataagg caaaacccca tttttacagt agtgatataa attgtaccta tatcactatg
     4381 aaaattgaat agtaaatatg agaaagacag ttgatttcaa aaaataggct ctttgtcaaa
     4441 tgatgttggt aaagagaaa
//
LOCUS       DARPZJ010000207         2565 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.143, whole genome shotgun sequence.
ACCESSION   DARPZJ010000207 DARPZJ010000000
VERSION     DARPZJ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.143"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            complement(39..341)
                     /locus_tag="SLE23_003061"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="SLE23_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1055..1345)
                     /locus_tag="SLE23_003062"
     CDS             complement(1055..1345)
                     /locus_tag="SLE23_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEI8469857.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..2244)
                     /locus_tag="SLE23_003063"
                     /pseudo
     CDS             complement(1553..2244)
                     /locus_tag="SLE23_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          759 a          472 c          356 g          978 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt gcttcgtcta
     1681 atttcttttg tgtatctgtt aactgatttc tacatttgtt ttttcttgtg tcagtgttgc
     1741 gatttgttga ttcaaaccat ttacagtatt ttgtaattct gaaagttttg cttgtgcttc
     1801 ttgtagtctt gctgtccaat ctgcattcag atgattgatt tcatcatttt tttggttgat
     1861 ctcatctagt ttgacattga tttcattttg tttgctttgt agttgtgcat ccttgctgac
     1921 taattgactt tctaagtttt gtttttctgc tgccgattga tttttttggt tttctaattc
     1981 atttactttt gtttggtatt cttggacatc tgcctttgaa tcttgcaatg tctgttcttt
     2041 ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct ttatctgtca atgtatgatc
     2101 aagctgtgtc agattctcat tgattgtatc aatatctgtc tctccacccc acaaaataat
     2161 ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat agaaatgcaa cgacaatccc
     2221 accagtaata aatttctttt tcatttgcat agctccttaa tccaatactt ttacatgcta
     2281 aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa ttacatatgt aattttaata
     2341 taaatactat caaatactca tttaatcctc cttttttatc tatttaaaaa atctttttta
     2401 tagagaaaaa tgcaggttaa tactttctta aataaatatt tatggtgaac aaaaacaaaa
     2461 aagcaagttt tattaaacgt aacccttttc atttcataga ttactgtatt tattacaaaa
     2521 aacgcggatt tgtcataaat tgtcatgctt cttttaccta tgaaa
//
LOCUS       DARPZJ010000208         2242 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.147, whole genome shotgun sequence.
ACCESSION   DARPZJ010000208 DARPZJ010000000
VERSION     DARPZJ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.147"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..148
                     /locus_tag="SLE23_003064"
     CDS             <1..148
                     /locus_tag="SLE23_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEI8469858.1"
                     /translation="LIVDLKLCNRTNYAVKLYKEGNMTVNQICEITNVSRASLYRKLS
                     EVNN"
     gene            362..1057
                     /gene="vanR"
                     /locus_tag="SLE23_003065"
     CDS             362..1057
                     /gene="vanR"
                     /locus_tag="SLE23_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEI8469859.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1035..2189
                     /locus_tag="SLE23_003066"
     CDS             1035..2189
                     /locus_tag="SLE23_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEI8469860.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          757 a          409 c          475 g          601 t
ORIGIN      
        1 tttgatagta gatttaaaac tttgcaacag aaccaattat gcggtaaagc tatataaaga
       61 aggaaatatg actgtaaatc aaatttgtga aattactaat gtatctaggg cttcattata
      121 caggaaatta tcagaagtga ataattagcc attctgtatt ccgctaatgg gcaatatttt
      181 taaagaagaa aaggaaacta taaaatatta acagcctcct agcgatgccg aaaagccctt
      241 tgataaaaaa agaatcatca tcttaagaaa ttcttagtca tttattatgt aaatgcttat
      301 aaattcggcc ctataatctg ataaattatt aagggcaaac ttatgtgaaa gggtgataac
      361 tatgagcgat aaaatactta ttgtggatga tgaacatgaa attgccgatt tggttgaatt
      421 atacttaaaa aacgagaatt atacggtttt caaatactat accgccaaag aagcattgga
      481 atgtatagac aagtctgaga ttgaccttgc catattggac atcatgcttc ccggcacaag
      541 cggccttact atctgtcaaa aaataaggga caagcacacc tatccgatta tcatgctgac
      601 cgggaaagat acagaggtag ataaaattac agggttaaca atcggcgcgg atgattatat
      661 aacgaagccc tttcgcccac tggagttaat tgctcgggta aaggcccagt tgcgccgata
      721 caaaaaattc agtggagtaa aggagcagaa cgaaaatgtt atcgtccact ccggccttgt
      781 cattaatgtt aacacccatg agtgttatct gaacgagaag cagttatccc ttactcccac
      841 cgagttttca atactgcgaa tcctctgtga aaacaagggg aatgtggtta gctccgagct
      901 gctatttcat gagatatggg gcgacgaata tttcagcaag agcaacaaca ccatcaccgt
      961 gcatatccgg catttgcgcg aaaaaatgaa cgacaccatt gataatccga aatatataaa
     1021 aacggtatgg ggggttggtt ataaaattga aaaataaaaa aaacgactat tccaaactag
     1081 aacgaaaact ttacatgtat atcgttgcaa ttgttgtggt agcaattgta ttcgtgttgt
     1141 atattcgttc aatgatccga gggaaacttg gggattggat cttaagtatt ttggaaaaca
     1201 aatatgactt aaatcacctg gacgcgatga aattatatca atattccata cggaacaata
     1261 tagatatctt tatttatgtg gcgattgtca ttagtattct tattctatgt cgcgtcatgc
     1321 tttcaaaatt cgcaaaatac tttgacgaga taaataccgg cattgatgta cttattcaga
     1381 acgaagataa acaaattgag ctttctgcgg aaatggatgt tatggaacaa aagctcaaca
     1441 cattaaaacg gactctggaa aagcgagagc aggatgcaaa gctggccgaa caaagaaaaa
     1501 atgacgttgt tatgtacttg gcgcacgata ttaaaacgcc ccttacatcc attatcggtt
     1561 atttgagcct gcttgacgag gctccagaca tgccggtaga tcaaaaggca aagtatgtgc
     1621 atatcacgtt ggacaaagcg tatcgactcg aacagctaat cgacgagttt tttgagatta
     1681 cacggtataa cctacaaacg ataacgctaa caaaaacgca catagaccta tactatatgc
     1741 tggtgcagat gaccgatgaa ttttatcctc agctttccgc acatggaaaa caggcggtta
     1801 ttcacgcccc cgaggatctg accgtgtccg gcgaccctga taaactcgcg agagtcttta
     1861 acaacatttt gaaaaacgcc gctgcataca gtgaggataa cagcatcatt gacattaccg
     1921 cgggcctctc cggggatgtg gtgtcaatcg aattcaagaa cactggaagc atcccaaaag
     1981 ataagctagc tgccatattt gaaaagttct ataggctgga caatgctcgt tcttccgata
     2041 cgggtggcgc gggacttgga ttggcgattg caaaagaaat tattgttcag catggagggc
     2101 agatttacgc ggaaagcaat gataactata cgacgtttag ggtagagctt ccagcgatgc
     2161 cagacttggt tgataaaagg aggtcctaag agatgtatat aattttggct ctttgtcaaa
     2221 tgatgttggt aaagagaaat ct
//
LOCUS       DARPZJ010000209         1467 bp    DNA     linear   BCT 20-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate C0517
            SAMN38330035-rid20277193.guided.162, whole genome shotgun sequence.
ACCESSION   DARPZJ010000209 DARPZJ010000000
VERSION     DARPZJ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38330035
            Sequence Read Archive: SRR26887595
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001992639.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001992639.1
            Genome Coverage       :: 366x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/20/2023 23:34:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,000
            Genes (coding)                    :: 2,923
            CDSs (with protein)               :: 2,923
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 38 of 77
            Pseudo Genes (incomplete)         :: 33 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38330035-rid20277193.guided.162"
                     /isolate="C0517"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Canada: Hamilton, Ontario"
                     /collection_date="2016"
     gene            <1..1348
                     /locus_tag="SLE23_003067"
     CDS             <1..1348
                     /locus_tag="SLE23_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HEI8469861.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          622 a          117 c          246 g          482 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgtt
//
